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Clinical Registry Unit (CRU)

The 1st Medical department of the Johannes Gutenberg University Medical hospital is a department of internal medicine specializing in treatment of patients with hepatological diseases, gastrointestinal tumors especially primary liver cancer, endocrinology, rheumatology and nephrology.

History

Starting in 2003 we have established a clinical registry to document the clinical history of patients with hepatocellular carcinoma. The registry data enabled us to identify the liver function as a critical factor for the prognosis and the feasibility of sorafenib in treating HCC after recurrence following liver transplantation.

Building upon this foundation we extended the functionality to support liver disease, other tumor entities and rheumatological and kidney diseases.

Advantages of the CRU for the patient

  •           Continuous reevaluation of therapy effectiveness and side effects to support shared decision making

  • Identification of patients for clinicalal trials
  • Continuous improvement of the clinical documentation

 Scientific benefits

  • Availability of large clinically validated datasets for

    • long-term outcome research
    • generation of hypotheses
    • validation of basic science results

“Learning from clinical practice for better treatment decisions”

Team

Head

PD Dr. Arndt Weinmann, MBA
E-Mail:  weinmann@mail.uni-mainz.de
Telephone: +49-6131-17-2666

Bioinformatics

Sandra Koch
E-Mail: sandra.koch@unimedizin-mainz.de
Telephone: +49-6131-17-

Cooperations

Data from the CRU has be used to externally validate clinical scores. If you are interested in a scientific cooperation using data of the CRU please contact Dr. Weinmann and we will check the feasibility of a cooperation.

Structure of the CRU

Aufbau_Clinical_Registry_Unit__CRU_.png

Coordinators

Coordinator

Collective

Email

Dr. Annette Grambihler

Autoimmune liver disease

annette.grambihler@unimedizin-mainz.de

Dr. Roman Klöckner

TACE

roman.kloeckner@unimedizin-mainz.de

Jun.-Prof. Dr. Jens Marquardt

Hepatocellular carinoma
Cholangiocellular carcinoma

jens.marquardt@unimedizin-mainz.de

PD Dr. Martin Sprinzl

Hepatocellular carcinoma
Liver transplantation
Viral hepatitis
Infectious diseases

martin.sprinzl@unimedizin-mainz.de

PD Dr. Arndt Weinmann

Hepatocellular carcinoma
Cholangiocellular carcinoma
Gastrointestinale cancer
BiobankLiver cirrhosis

weinmann@mail.uni-mainz.de

PD Dr. Julia Weinmann-Menke

Systemic lupus erythematodes
Vasculitis
Rheumatology
Renal transplantation

julia.weinmann-menke@unimedizin-mainz.de

PD Dr. Marcus Wörns

Hepatocellular carcinoma
Cholangiocellular carcinoma
Gastrointestinale cancer
Liver cirrhosis
Autoimmune liver disease

woerns@uni-mainz.de

PD Dr. Tim Zimmermann

Liver transplantation

tim.zimmermann@unimedizin-mainz.de

Publications based on data of the CRU