Junior group leader
Deputy Head Preventive Cardiology and Medical Prevention, Senior Physician Cardiology I
DZHK PI
06131 17-2594
Weitere Informationen
The goal of the „Fellowship Clinical Epidemiology“ within Module B “Clinical Epidemiology” of the Center for Thrombosis und Hemostasis (CTH) is the synergistic combination of epidemiological training („Master of Science in Epidemiology“ program) and scientific work on the field “Oral Anticoagulation” (OAC). OAC with vitamin K antagonists is an established therapy for decades, although evidence on the quality and management of anticoagulation with phenprocoumon – which is predominantly applied in Germany – is limited. In recent years, new direct oral anticoagulative drugs (factor Xa and thrombin inhibitors) have been successfully investigated in randomized clinical trials and are now available for clinical practice. Increasing life-expectancy and the demographic change will lead to a growing need for oral anticoagulation treatment in the future as most of the diseases like e.g. atrial fibrillation – the most frequent indication – and venous thromboembolism are more prevalent in the elderly. An expanding complexity of hemostaseology results in high demands on the physicians in charge: Multi-morbidity of older patients and new diversity of options for OAC available by novel anticoagulative drugs require a careful consideration of benefits and risks of the treatment. Major efforts are needed to provide scientific evidence to cope with these clinical challenges.
The main subject of this Epidemiology Fellowship application is to comprehensively evaluate oral anticoagulation therapy in the clinical setting. We aim to get insights from the thrombEVAL study program on the physicians´ perception of current oral anticoagulation therapy, the clinical application of bridging therapy and the long-term follow-up of anticoagulated patients. In addition, we will investigate (potential) effects of oral anticoagulants on hemostasis and the course of cardiovascular disease in an epidemiological study. This will contribute to enhance our current knowledge of the pathophysiological mechanisms involved in the development of cardiovascular diseases and the complex interplay between hemostasis, inflammation and immune system.
Mentors of the Epidemiology-Fellow are Professor Philipp Wild, Head of the Module Clinical Epidemiology at the CTH and Head of Institute for Preventive Cardiology and Preventive Medicine, and Professor Hugo ten Cate, Professor of Clinical Thrombosis and Hemostasis at the Cardiovascular Research Institute (CARIM) Maastricht and Fellow of the Gutenberg Forschungskolleg (GFK) of the Johannes Gutenberg-University Mainz
07/2001 | German secondary school diploma (Abitur) |
2001-2002 | Civil service, Hospital Pegnitz |
10/2002- 06/2009 | Medical studies, Julius-Maximilians-University Würzburg |
2005-2008 | Research assistant and Doctoral Fellow, AG Neuroimmunology, Department of Neurology, University-Hospital Würzburg |
| Doctoral thesis: “Regulation of Junctional Adhesion Molecule A in cerebral endothelial cells under proinflammatory conditions” |
Since 09/2009 | Clinical resident at the Department of Medicine 2 (Cardiology / Angiology) |
Since 04/2010 | Head of project management of the thrombEVAL study program |
Since 2011 | Research fellow Gutenberg Health Study |
04/2013 | Chair of poster session „Cardiovascular risks” and member of the jury for the “Rudolf-Thauer-Posterpreis” at the annual meeting of the German Cardiac Society (DGK) 2013 |
05/2013 | Young Investigator Grant for the “CTH Spring School on the Science and Practice of Venous Thromboembolism” |
Since 10/2013 | Postgradual studies “Master of Science in Epidemiology” at Institute for Medicinal Biometry, Epidemiology and Informatics (IMBEI) Mainz |
Since 02/2014 | Postodoctoral Fellowship Clinical Epidemiology |
Since 03/2014 | Member of the Working Group "Thrombosis" of the European Society of Cardiology |
Since 07/2014 | Scientific Advisor for CTH Platform Biodata Banking |
Since 10/2014 | Research Fellow of the German Center for Cardiovascular Research (DZHK) |