Visual Universitätsmedizin Mainz

Pulmonary Embolism Thrombolysis Study (PEITHO)

  • Studienleiter: Prof. Dr. Stavros Konstantinides
  • - ID.Nr.: NCT00639743

A prospective, randomized, double-blind, placebo-controlled, international, multicentre, parallel-group comparison trial evaluating the efficacy and safety of single i.v. bolus tenecteplase plus standard anticoagulation as compared with standard anticoagulation in normotensive patients with acute pulmonary embolism and with echocardiographic (or spiral CT) and laboratory evidence of right ventricular dysfunction.

Sponsor: Assistance Publique d’ Hôpitaux de Paris

Weitere Informationen zu den Inhalten der PEITHO-Studie (Pdf-file, 118,9 KB)

Study Type


Study Design

Endpoint Classification: Efficacy Study


Intervention Model: Parallel Assignment


Masking: Double Blind (Subject, Investigator)


Primary Purpose: Treatment

Official Title

Bolus Tenecteplase Plus Standard Anticoagulation as Compared With Standard Anticoagulation in Normotensive Patients


Pulished; 2-Year Follow-Up Recruiting

Steering Committee

Stavros Konstantinides, Mainz, DE (Chair), Guy Meyer, Paris, FR (Co-Chair), and the PEITHO Investigators