My Bibliography

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Göllner M, Ihrig-Biedert I, Petermann V, Saurin S, Oelze M, Kröller-Schön S, Vujacic-Mirski K, Kuntic M, Pautz A, Daiber A, Kleinert H. NOX2ko Mice Show Largely Increased Expression of a Mutated NOX2 mRNA Encoding an Inactive NOX2 Protein. Antioxidants (Basel). 2020 Oct 26;9(11). doi: 10.3390/antiox9111043. PubMed PMID: 33114493; PubMed Central PMCID: PMC7692237.

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Käfer R, Schmidtke L, Schrick K, Montermann E, Bros M, Kleinert H, Pautz A. The RNA-Binding Protein KSRP Modulates Cytokine Expression of CD4(+) T Cells. J Immunol Res. 2019;2019:4726532. doi: 10.1155/2019/4726532. eCollection 2019. PubMed PMID: 31511826; PubMed Central PMCID: PMC6714327.

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Gather F, Schmitz K, Koch K, Vogt LM, Pautz A, Kleinert H. Regulation of human inducible nitric oxide synthase expression by an upstream open reading frame. Nitric Oxide. 2019 Jul 1;88:50-60. doi: 10.1016/j.niox.2019.04.008. Epub 2019 Apr 18. PubMed PMID: 31004763.

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Schmidtke L, Schrick K, Saurin S, Käfer R, Gather F, Weinmann-Menke J, Kleinert H, Pautz A. The KH-type splicing regulatory protein (KSRP) regulates type III interferon expression post-transcriptionally. Biochem J. 2019 Jan 31;476(2):333-352. doi: 10.1042/BCJ20180522. PubMed PMID: 30578289.

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Bros M, Youns M, Kollek V, Buchmüller D, Bollmann F, Seo EJ, Schupp J, Montermann E, Usanova S, Kleinert H, Efferth T, Reske-Kunz AB. Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State. Front Pharmacol. 2018;9:915. doi: 10.3389/fphar.2018.00915. eCollection 2018. PubMed PMID: 30174602; PubMed Central PMCID: PMC6108336.

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Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kröller-Schön S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Münzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res. 2018 Feb 1;114(2):312-323. doi: 10.1093/cvr/cvx197. PubMed PMID: 29036612.

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Käfer R, Schrick K, Schmidtke L, Montermann E, Hobernik D, Bros M, Chen CY, Kleinert H, Pautz A. Inactivation of the KSRP gene modifies collagen antibody induced arthritis. Mol Immunol. 2017 Jul;87:207-216. doi: 10.1016/j.molimm.2017.05.003. Epub 2017 May 13. PubMed PMID: 28511090.

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Waisman A, Hövelmeyer N, Diefenbach A, Schuppan D, Reddehase MJ, Kleinert H, Kaina B, Grabbe S, Galle PR, Theobald M, Zipp F, Sahin U, Türeci Ö, Kreiter S, Langguth P, Decker H, van Zandbergen G, Schild H. Past, present and future of immunology in Mainz. Cell Immunol. 2016 Oct;308:1-6. doi: 10.1016/j.cellimm.2016.09.001. PubMed PMID: 27719802.

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Härdle L, Bachmann M, Bollmann F, Pautz A, Schmid T, Eberhardt W, Kleinert H, Pfeilschifter J, Mühl H. Erratum: Tristetraprolin regulation of interleukin-22 production. Sci Rep. 2015 Dec 18;5:17160. doi: 10.1038/srep17160. PubMed PMID: 26681449; PubMed Central PMCID: PMC4683574.

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Härdle L, Bachmann M, Bollmann F, Pautz A, Schmid T, Eberhardt W, Kleinert H, Pfeilschifter J, Mühl H. Tristetraprolin regulation of interleukin-22 production. Sci Rep. 2015 Oct 21;5:15112. doi: 10.1038/srep15112. PubMed PMID: 26486958; PubMed Central PMCID: PMC4613560.

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Bollmann F, Jäckel S, Schmidtke L, Schrick K, Reinhardt C, Jurk K, Wu Z, Xia N, Li H, Erkel G, Walter U, Kleinert H, Pautz A. Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice. PLoS One. 2015;10(6):e0130401. doi: 10.1371/journal.pone.0130401. eCollection 2015. PubMed PMID: 26076475; PubMed Central PMCID: PMC4468253.

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Bollmann F, Art J, Henke J, Schrick K, Besche V, Bros M, Li H, Siuda D, Handler N, Bauer F, Erker T, Behnke F, Mönch B, Härdle L, Hoffmann M, Chen CY, Förstermann U, Dirsch VM, Werz O, Kleinert H, Pautz A. Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity. Nucleic Acids Res. 2014 Nov 10;42(20):12555-69. doi: 10.1093/nar/gku1033. Epub 2014 Oct 28. PubMed PMID: 25352548; PubMed Central PMCID: PMC4227754.

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Scherer O, Steinmetz H, Kaether C, Weinigel C, Barz D, Kleinert H, Menche D, Müller R, Pergola C, Werz O. Targeting V-ATPase in primary human monocytes by archazolid potently represses the classical secretion of cytokines due to accumulation at the endoplasmic reticulum. Biochem Pharmacol. 2014 Oct 15;91(4):490-500. doi: 10.1016/j.bcp.2014.07.028. Epub 2014 Aug 12. PubMed PMID: 25107704.

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Henke J, Erkel G, Brochhausen C, Kleinert H, Schwarting A, Menke J, Pautz A. The fungal lactone oxacyclododecindione is a potential new therapeutic substance in the treatment of lupus-associated kidney disease. Kidney Int. 2014 Oct;86(4):780-9. doi: 10.1038/ki.2014.109. Epub 2014 Apr 9. PubMed PMID: 24717299.

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Bollmann F, Wu Z, Oelze M, Siuda D, Xia N, Henke J, Daiber A, Li H, Stumpo DJ, Blackshear PJ, Kleinert H, Pautz A. Endothelial dysfunction in tristetraprolin-deficient mice is not caused by enhanced tumor necrosis factor-α expression. J Biol Chem. 2014 May 30;289(22):15653-65. doi: 10.1074/jbc.M114.566984. Epub 2014 Apr 11. PubMed PMID: 24727475; PubMed Central PMCID: PMC4140920.

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Siuda D, Wu Z, Chen Y, Guo L, Linke M, Zechner U, Xia N, Reifenberg G, Kleinert H, Forstermann U, Li H. Social isolation-induced epigenetic changes in midbrain of adult mice. J Physiol Pharmacol. 2014 Apr;65(2):247-55. PubMed PMID: 24781734.

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Reifenberg K, Cheng F, Twardowski L, Küpper I, Wiese E, Bollmann F, Kleinert H, Blessing M, Lackner KJ, Torzewski M. T cell-specific overexpression of TGFß1 fails to influence atherosclerosis in ApoE-deficient mice. PLoS One. 2013;8(12):e81444. doi: 10.1371/journal.pone.0081444. eCollection 2013. PubMed PMID: 24339930; PubMed Central PMCID: PMC3855303.

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Oelze M, Knorr M, Kröller-Schön S, Kossmann S, Gottschlich A, Rümmler R, Schuff A, Daub S, Doppler C, Kleinert H, Gori T, Daiber A, Münzel T. Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression. Eur Heart J. 2013 Nov;34(41):3206-16. doi: 10.1093/eurheartj/ehs100. Epub 2012 May 3. PubMed PMID: 22555214.

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Casper I, Nowag S, Koch K, Hubrich T, Bollmann F, Henke J, Schmitz K, Kleinert H, Pautz A. Post-transcriptional regulation of the human inducible nitric oxide synthase (iNOS) expression by the cytosolic poly(A)-binding protein (PABP). Nitric Oxide. 2013 Sep 1;33:6-17. doi: 10.1016/j.niox.2013.05.002. Epub 2013 May 25. PubMed PMID: 23711718.

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Xia N, Strand S, Schlufter F, Siuda D, Reifenberg G, Kleinert H, Förstermann U, Li H. Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol. Nitric Oxide. 2013 Aug 1;32:29-35. doi: 10.1016/j.niox.2013.04.001. Epub 2013 Apr 10. PubMed PMID: 23583951.

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Bollmann F, Fechir K, Nowag S, Koch K, Art J, Kleinert H, Pautz A. Human inducible nitric oxide synthase (iNOS) expression depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation factor 4E (elF4E)-mediated nucleocytoplasmic mRNA transport. Nitric Oxide. 2013 Apr 1;30:49-59. doi: 10.1016/j.niox.2013.02.083. Epub 2013 Mar 5. PubMed PMID: 23471078.

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Schmidt N, Art J, Forsch I, Werner A, Erkel G, Jung M, Horke S, Kleinert H, Pautz A. The anti-inflammatory fungal compound (S)-curvularin reduces proinflammatory gene expression in an in vivo model of rheumatoid arthritis. J Pharmacol Exp Ther. 2012 Oct;343(1):106-14. doi: 10.1124/jpet.112.192047. Epub 2012 Jul 5. PubMed PMID: 22767531.

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Siuda D, Zechner U, El Hajj N, Prawitt D, Langer D, Xia N, Horke S, Pautz A, Kleinert H, Förstermann U, Li H. Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cells. Basic Res Cardiol. 2012 Sep;107(5):283. doi: 10.1007/s00395-012-0283-3. Epub 2012 Jul 13. PubMed PMID: 22791246.

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Daiber A, Oelze M, Wenzel P, Bollmann F, Pautz A, Kleinert H. Heme oxygenase-1 induction and organic nitrate therapy: beneficial effects on endothelial dysfunction, nitrate tolerance, and vascular oxidative stress. Int J Hypertens. 2012;2012:842632. doi: 10.1155/2012/842632. Epub 2012 Mar 7. PubMed PMID: 22506100; PubMed Central PMCID: PMC3312327.

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Torzewski M, Wenzel P, Kleinert H, Becker C, El-Masri J, Wiese E, Brandt M, Pautz A, Twardowski L, Schmitt E, Münzel T, Reifenberg K. Chronic inflammatory cardiomyopathy of interferon γ-overexpressing transgenic mice is mediated by tumor necrosis factor-α. Am J Pathol. 2012 Jan;180(1):73-81. doi: 10.1016/j.ajpath.2011.09.006. Epub 2011 Nov 1. PubMed PMID: 22051774.

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Schuhmacher S, Oelze M, Bollmann F, Kleinert H, Otto C, Heeren T, Steven S, Hausding M, Knorr M, Pautz A, Reifenberg K, Schulz E, Gori T, Wenzel P, Münzel T, Daiber A. Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy. Diabetes. 2011 Oct;60(10):2608-16. doi: 10.2337/db10-1395. Epub 2011 Aug 15. PubMed PMID: 21844097; PubMed Central PMCID: PMC3178293.

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Oelze M, Knorr M, Schell R, Kamuf J, Pautz A, Art J, Wenzel P, Münzel T, Kleinert H, Daiber A. Regulation of human mitochondrial aldehyde dehydrogenase (ALDH-2) activity by electrophiles in vitro. J Biol Chem. 2011 Mar 18;286(11):8893-900. doi: 10.1074/jbc.M110.190017. Epub 2011 Jan 20. PubMed PMID: 21252222; PubMed Central PMCID: PMC3058968.

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Hausding M, Tepe M, Ubel C, Lehr HA, Röhrig B, Höhn Y, Pautz A, Eigenbrod T, Anke T, Kleinert H, Erkel G, Finotto S. Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma. Int Immunol. 2011 Jan;23(1):1-15. doi: 10.1093/intimm/dxq451. Epub 2010 Dec 6. PubMed PMID: 21135031.

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NPB . Effect of KHSRP KO in adult mouse neocortex (CTX). 2021/02. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA698976. NCBI:BioProject: PRJNA698976.

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Department of Molecular Medicine (MOMA), Aarhus University Hospital. Total RNA-Seq of KHSRP knockdown (KD) and control samples in HepG2 and K562. 2020/02. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA608915. NCBI:BioProject: PRJNA608915.

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Semmelweis University. Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell based in vitro disease-modelling: Convergence of schizophrenia and autism-related cellular phenotypes. 2020/02. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA607812. NCBI:BioProject: PRJNA607812.

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Gallouzi . Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy. 2019/07. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA554451. NCBI:BioProject: PRJNA554451.

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Kochi Medical School. RNA immunoprecipitation (RIP) of KHSRP from pancreatic cancer cell extracts cultured on fibronectin. 2018/10. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA494712. NCBI:BioProject: PRJNA494712.

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Yale_Giraldez_Group. mRNA structure dynamics identifies RNA remodelers and functional elements during embryogenesis: KHSRP iCLIP. 2018/05. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA473836. NCBI:BioProject: PRJNA473836.

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NIH. Genome-wide profiling of cervical RNA-binding proteins identified HPV regulation of RNASEH2A expression by viral E7 and E2F1. 2018/05. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA454568. NCBI:BioProject: PRJNA454568.

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Charles Craik . KH-type splicing regulatory protein controls colorectal cancer cell growth and modulates the tumor microenvironment. 2018/03. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA445699. NCBI:BioProject: PRJNA445699.

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sichuan university. Homo sapiens, Thyroid cancer: tumor vs. precancerous lesions. 2017/08. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA400625. NCBI:BioProject: PRJNA400625.

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National Taiwan University. Homo sapiens, Expression data from KSRP knockdown lung cancer cell. 2017/07. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA395685. NCBI:BioProject: PRJNA395685.

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Department of Human Genetics . Homo sapiens, KH-type splicing regulatory protein (KHSRP) is involved in esophageal squamous cell carcinoma progression through regulating a subset of microRNAs [mRNA]. 2017/05. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA388433. NCBI:BioProject: PRJNA388433.

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Department of Human Genetics . Homo sapiens, KH-type splicing regulatory protein (KHSRP) is involved in esophageal squamous cell carcinoma progression through regulating a subset of microRNAs [miRNA]. 2017/05. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA388432. NCBI:BioProject: PRJNA388432.

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Department of Human Genetics . KH-type splicing regulatory protein (KHSRP) is involved in esophageal squamous cell carcinoma progression through regulating a subset of microRNAs. 2017/05. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA388429. NCBI:BioProject: PRJNA388429.

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Peking Union Medical College. Homo sapiens, RNA binding protein KSRP mediated miRNAs processing reciprocally regulates granulocytic and monocytic differentiation. 2016/09. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA344330. NCBI:BioProject: PRJNA344330.

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Peking Union Medical College. Homo sapiens, KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression. 2016/09. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA343476. NCBI:BioProject: PRJNA343476.

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National Taiwan University. Homo sapiens, Expression data from KSRP overexpression and knockdown lung cancer cell. 2016/06. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA325776. NCBI:BioProject: PRJNA325776.

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San Raffaele Scientific Institute. Mus musculus strain:NMuMg, Mus musculus NMuMg Cells TGFb treated transcriptome. 2016/02. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA312702. NCBI:BioProject: PRJNA312702.

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915 . Mus musculus, Destabilization of Nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fiber formation. 2014/04. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA245448. NCBI:BioProject: PRJNA245448.

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GFU . Mus musculus, KSRP-mediated Transcriptome reshaping. 2012/06. In: BioProject [Internet]. Bethesda, MD: National Library of Medicine (US), National Center for Biotechnology Information; 2011-. Available from: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA169319. NCBI:BioProject: PRJNA169319.

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Pautz A, Art J, Hahn S, Nowag S, Voss C, Kleinert H. Regulation of the expression of inducible nitric oxide synthase. Nitric Oxide. 2010 Sep 15;23(2):75-93. doi: 10.1016/j.niox.2010.04.007. Epub 2010 May 8. Review. PubMed PMID: 20438856.

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Schmidt N, Pautz A, Art J, Rauschkolb P, Jung M, Erkel G, Goldring MB, Kleinert H. Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes. Biochem Pharmacol. 2010 Mar 1;79(5):722-32. doi: 10.1016/j.bcp.2009.10.012. Epub 2009 Oct 23. PubMed PMID: 19854161; PubMed Central PMCID: PMC3951130.

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Bros M, Wiechmann N, Besche V, Art J, Pautz A, Grabbe S, Kleinert H, Reske-Kunz AB. The RNA binding protein tristetraprolin influences the activation state of murine dendritic cells. Mol Immunol. 2010 Feb;47(5):1161-70. doi: 10.1016/j.molimm.2009.11.002. Epub 2009 Nov 28. PubMed PMID: 19945750.