Visual Universitätsmedizin Mainz

Retz group

 

 

Univ.-Prof. Dr. Wolfgang Retz

curriculum vitæ

Department of Psychiatry and Psychotherapy

University Medical Center Mainz

Untere Zahlbacherstr. 8

D-55131 Mainz

wolfgang.retz@unimedizin-mainz.de

 

Group leader:

Univ.-Prof. Dr. Wolfgang Retz

 

Researchers:

Dr. med. Sergiy. Davydenko

M.Sc.Psych. Priscilla Gregorio Hertz

Dipl.-Psych. Marcus Müller

Dr. med. Dr. biol. hum. Dipl.-Psych. Daniel Turner

 

Forensic psychiatric research at the Department of Psychiatry and Psychotherapy focuses on psychopathological patterns and mental disorders that are important in the development of social adjustment disorders and delinquent behavior. These comprise above all impulsive and aggressive behavior, disorders of emotion regulation, personality disorders, as well as the attention deficit-/hyperactivity disorder (ADHD).

In terms of methodology and content, the main goal is to utilize the psychiatric and psychological research skills available in the Psychiatric and Psychotherapy Clinic for investigating relevant questions from a criminological point of view.

ADHD as one of the most frequent developmental disorders is often associated with conduct problems in childhood and delinquent behavior in later life. Therefore, we have set us the task to distangle the relation between ADHD and social maladaptation and delinquency, in particular. The group is also involved in the development of diagnostic tools and the evaluation of treatment programs for adult ADHD in general psychiatry.

 

Major research topics:

  • Neurobiological correlates of aggressive-impulsive behavior and emotional dysregulation in offenders

  • Interactions of genetic and environmental factors for social adaptation and the development of aggressive-violent behavior

  • Impact of ADHD in the development of different forms of delinquent behavior


Research collaborations:

  • Institute of Forensic Psychology and Psychiatry of the University of Saarland (Prof. Dr. Rösler),

  • Department of Child and Adolescent Psychiatry of the University Medical Center Mainz (Prof. Dr. Huss),

  • Laboratory for Psychiatric Neurobiology of the Psychiatric University Hospital Würzburg (Prof. Dr. Reif).

  • Center for Children Youth and Families at the University of Vermont (Prof. Thomas M. Achenbach)

Important publications:

1. Fernàndez-Castillo N, Gan G, van Donkelaar MMJ, Vaht M, Weber H, Retz W, Meyer-Lindenberg A, Franke B, Harro J, Reif A, Faraone SV, Cormand B. RBFOX1, encoding a splicing regulator, is a candidate gene for aggressive behavior. Eur Neuropsychopharmacol. 2017. [Epub ahead of print]

2: Philipp-Wiegmann F, Rösler M, Clasen O, Zinnow T, Retz-Junginger P, Retz W. ADHD modulates the course of delinquency: a 15-year follow-up study of young incarcerated man. Eur Arch Psychiatry Clin Neurosci. 2017. [Epub ahead of print] PubMed PMID: 28612143.

3: Philipsen A, Jans T, Graf E, Matthies S, Borel P, Colla M, Gentschow L, Langner D, Jacob C, Groß-Lesch S, Sobanski E, Alm B, Schumacher-Stien M, Rösler M, Retz W, Retz-Junginger P, Kis B, Abdel-Hamid M, Heinrich V, Huss M, KornmannC, Bürger A, Perlov E, Ihorst G, Schlander M, Berger M, Tebartz van Elst L; Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS) Consortium. Effects of Group Psychotherapy, Individual Counseling, Methylphenidate, and Placebo in the Treatment of Adult Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2015;72(12):1199-210. Erratum in: JAMA Psychiatry. 2016;73(1):90.

4: Retz W, Retz-Junginger P, Römer K, Rösler M. [Standardised psychopathological rating scales for the diagnosis of ADHD in adults]. Fortschr Neurol Psychiatr. 2013;81(7):381-9.

5: Retz W, Boureghda SS, Retz-Junginger P, Philipp-Wiegmann F, Rösler M. Clinical symptoms of ADHD and psychopathy in perpetrators. Atten Defic Hyperact Disord. 2013;5(1):47-57.

6: Philipp-Wiegmann F, Rösler M, Römer KD, Schneider M, Baumgart S, Retz W. Reduced cortical inhibition in violent offenders: a study with transcranial magnetic stimulation. Neuropsychobiology. 2011;64(2):86-92.

7: Retz W, Rösler M. Association of ADHD with reactive and proactive violent behavior in a forensic population. Atten Defic Hyperact Disord. 2010;2(4):195-202.

8: Retz W, Rösler M, Ose C, Scherag A, Alm B, Philipsen A, Fischer R, Ammer R; Study Group. Multiscale assessment of treatment efficacy in adults with ADHD: a randomized placebo-controlled, multi-centre study with extended-release methylphenidate. World J Biol Psychiatry. 2012;13(1):48-59.

9: Rösler M, Fischer R, Ammer R, Ose C, Retz W. A randomised, placebo-controlled, 24-week, study of low-dose extended-release methylphenidate in adults with attention-deficit/hyperactivity disorder. Eur Arch Psychiatry Clin Neurosci. 2009;259(2):120-9. Erratum in: Eur Arch Psychiatry Clin Neurosci. 2009;259(6):368.

10: Reif A, Rösler M, Freitag CM, Schneider M, Eujen A, Kissling C, Wenzler D, Jacob CP, Retz-Junginger P, Thome J, Lesch KP, Retz W. Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology. 2007 Nov;32(11):2375-83.