2016

Herrtwich L., Nanda I., Evangelou K., Nikolova T., Horn V., Sagar, Erny D., Stefanowski J., Rogell L., Klein C., Gharun K., Follo M., Seidl M., Kremer B., Münke N., Senges J., Fliegauf M., Aschman T., Pfeifer D., Sarrazin S., Sieweke M., Wagner D., Dierks C., Haaf T., Ness T., Zaiss M., Voll R., Deshmukh S., Prinz M., Goldmann T., Hölscher C., Hauser A., Lopez-Contreras A., Grün D., Gorgoulis V., Diefenbach A., Henneke P., Triantafyllopoulou A. (2016) DNA damage signaling instructs polyploid macrophage fate in granulomas, Cell, 167, 1264-1280

Zahnreich S., Ebersberger A., Karle H., Kaina B., Schmidberger H. (2016) Quantification of radiation biomarkers in leukocytes of breast cancer patients treated with different modalities of 3D-CRT or IMRT, Radiation Research, 186, 508-516 

Christmann M., Kaina B. (2016) MGMT - A critical DNA repair gene target for chemotherapy resistance, in 2nd edition, M.R. Kelley and M.L. Fishel (edts), DNA Repair in Cancer Therapy, Molecular Targets and Clinical Applications, 55-82

Dietrich, C. (2016) Antioxidant functions of the aryl hydrocarbon receptor, Hindawi Publishing Corporation, Stem Cells International, volume 2016, 1-10

Roos W., Krumm A. (2016) The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair, Nucleic Acids Research, 44, 10017-10030

Fahrer J., Kaina B. (2016) Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens, Food and Chemical Toxicology, in press

Christmann M., Boisseau C., Kitzinger R., Berac C., Allmann S., Sommer T., Aasland D., Kaina B., Tomicic M. (2016) Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations, Nucleic Acids Research, 44, 10727-10743

Kaina B. (2016) DNA repair in cancer therapy with methylating anticancer drugs: improving therapeutic efficacy and reducing side effects, Carcinogenesis, Teratogenesis and Mutagenesis, 28, 333-347

Berte N., Piée-Staffa A., Piecha N., Wang M., Borgmann K., Kaina B., Nikolova T. (2016) Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugs, Molecular Cancer Therapeutics, 15, 2665-2678

Berte N., Lokan S., Eich M., Kim E., Kaina B. (2016) Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence, Oncotarget, 7, 67235-67250

Mimmler M., Peter S., Kraus A., Stroh S., Nikolova T., Seiwert N., Hasselwander S., Neitzel C., Haub J., Monien B., Nicken P., Steinberg P., Shay J., Kaina B., Fahrer J. (2016) DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP, Nucleic Acids Research, 44, 10259-10276

Fahrer J., (2016) Food-borne carcinogens, Encyclopaedia of Cancer, M. Schwab (ed.), Springer Verlag Berlin-Heidelberg (Buchkapitel), DOI 10.1007/978-3-642-27841-9_7235-1

Mikhed Y., Fahrer J., Oelze M., Kröller-Schön S., Steven S., Welschof P., Zinßius E., Stamm P., Kashani F., Roohani S., Kress J., Ullmann E., Tran L., Schulz E., Epe B., Kaina B., Münzel T., Daiber A. (2016) Nitroglycerin induces DNA damage and vascular cell death in the setting of nitrate tolerance, Basic Research in Cardiology, 111:52,  DOI: 10.1007/s00395-016-0571-4

Ebert F., Thomann M., Witt B., Müller S., Meyer S., Weber T., Christmann M., Schwerdtle T. (2016) Evaluating long-term cellular effects of the arsenic species thio-DMA^V: qPCR-based gene expression as screening tool, Journal of Trace Elements in Medicine and Biology, 37, 78-84

Allgayer J., Kitsera N., Bartelt S., Epe B., Khobta A. (2016) Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine, Nucleic Acids Research, 44, 7267-7280

Krumm A., Barckhausen C., Kücük P., Tomaszowski K., Loquai C., Fahrer J., Krämer O., Kaina B., Roos W. (2016) Enhanced Histone Deacetylase activity in malignant melanoma provokes RAD51 and FANCD2-triggered drug resistance, Cancer Research, 76, 3067-3077

Switzeny O., Christmann M., Renovanz M., Giese A., Sommer C., Kaina B. (2016) MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response, Clinical Epigenetics, 8:49, DOI 10.1186/s13148-016-0204-7

Motzek A., Knezevic J., Switzeny O., Cooper A., Baric I., Beluzic R., Strauss K., Puffenberger E., Mudd S., Vugrek O., Zechner U. (2016) Abnormal hypermethylation at imprinting control regions in patients with S-Adenosylhomocysteine hydrolase (AHCY) deficiency, Plos One, 11:e0151261

Heylmann D., Kaina B. (2016) The γH2AX DNA damage assay from a drop of blood, Scientific Reports, 6:22682

Faust D., Nikolova T., Wätjen W., Kaina B., Dietrich C. (2016) The Brassica-derived phytochemical indolo [3,2-b] carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation, Archives of Toxicology, in press 

Roos W. P., Thomas A.D., Kaina B. (2016) DNA damage and the balance between survival and death in cancer biology, Nature Reviews Cancer, 16, 20-33

Dörsam B., Fahrer J. (2016) The disulfide compound α-lipoic acid and its derivatives: a novel class of anticancer agents targeting mitochondria, Cancer Letters, 371, 12-19

Sonnemann J., Kahl M., Siranjeevi M., Blumrich A., Blümel L., Becker S., Wittig S., Winkler R., Krämer O., Beck J. (2016) Reverse chemomodulatory effects of the SIRT1 activators resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity,  Cancer Research and Clinical Oncology 142, 17-26