Selected Publications


  • Lin, C.P.*, Levy, P.L.*, Alflen, A.*, Apriamashvili, G.*, Ligtenberg, M.A., Vredevoogd, D.W., Bleijerveld, O.B., Alkan, F., Malka, Y., Hoekman, L., et al. (2024). Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness. Cancer Cell.
    *These authors contributed equally

  • Alflen, A., Aranda Lopez, P., Hartmann, A.K., Maxeiner, J., Bosmann, M., Sharma, A., Platten, J., Ries, F., Beckert, H., Ruf, W., et al. (2020). Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis. Immunobiology 225, 151867. 

  • Ries, F., Alflen, A., Aranda Lopez, P., Beckert, H., Theobald, M., Schild, H., Teschner, D., and Radsak, M.P. (2019). Antifungal Drugs Influence Neutrophil Effector Functions. Antimicrob Agents Chemother 63. 

  • Kuemmel, A., Alflen, A., Schmidt, L.H., Sebastian, M., Wiewrodt, R., Schulze, A.B., Buhl, R., and Radsak, M. (2018). Soluble Triggering Receptor Expressed on Myeloid Cells 1 in lung cancer. Sci Rep 8, 10766. 

  • Alflen, A., Stadler, N., Aranda Lopez, P., Teschner, D., Theobald, M., Heß, G., and Radsak, M.P. (2018). Idelalisib impairs TREM-1 mediated neutrophil inflammatory responses. Sci Rep 8, 5558. 

  • Alflen, A., Prüfer, S., Ebner, K., Reuter, S., Aranda Lopez, P., Scharrer, I., Banno, F., Stassen, M., Schild, H., Jurk, K., et al. (2017). ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis. Sci Rep 7, 7184. 

  • Lopez, P.A., Denny, M., Hartmann, A.K., Alflen, A., Probst, H.C., von Stebut, E., Tenzer, S., Schild, H., Stassen, M., Langguth, P., et al. (2017). Transcutaneous immunization with a novel imiquimod nanoemulsion induces superior T cell responses and virus protection. J Dermatol Sci 87, 252-259. 

  • Stadler, N., Hasibeder, A., Lopez, P.A., Teschner, D., Desuki, A., Kriege, O., Weber, A.N.R., Schulz, C., Michel, C., Heβ, G., et al. (2017). The Bruton tyrosine kinase inhibitor ibrutinib abrogates triggering receptor on myeloid cells 1-mediated neutrophil activation. Haematologica 102, e191-e194. 

  • Hasibeder, A., Stein, P., Brandwijk, R., Schild, H., and Radsak, M.P. (2015). Evaluation and Validation of the Detection of soluble Triggering Receptor Expressed on Myeloid Cells 1 by Enzyme-linked immunosorbent Assay. Sci Rep 5, 15381. 

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