Visual Universitätsmedizin Mainz

Information on the Study

Characteristics of the Gutenberg Post-COVID Study

The interdisciplinary nature of the concept

…allows for a systems medicine approach to the disease process of Post-COVID and differentiation from other diseases.

The study includes individuals with various severities of the course of acute SARS-CoV-2 infection

…unknowingly infected individuals who did not require any treatment in regards to acute COVID-19 illness and individuals who required outpatient or intensive care treatment.

The study will capture subclinical changes…

…that are not currently (yet) manifesting in symptoms.

The development of the still missing objectified diagnosis and needs-based therapy

…shall be supported by the study. 

For the first time, data on Post-COVID will be available for Rhineland-Palatinate…

…which will serve as a basis for establishing targeted care for affected individuals.



The comprehensive characterization of people with a history of COVID-19 is a fundamental requirement for the breakdown of the still poorly understood clinical picture of Post-COVID.

The goal of the Gutenberg Post-COVID Study includes the determination of the frequency, severity and risk factors of persistent - subclinical and clinical - changes in health with consideration of the organ systems and psychiatric/psychosomatic effects. In addition, possible pathomechanisms in the development and course of Post-COVID can be determined with an extensive bio bank.

Examination Program of the Gutenberg Post-COVID Study

Within the framework of the Gutenberg Post-COVID Study, comprehensive physical and psychological examinations are performed in various departments of the University Medical Center Mainz, which are relevant for the research of Post-COVID.

Project Duration

A project duration of 10 months is estimated for data collection. The project started in December 2021.

Study Funding


The study is funded by the Ministry of Science and Health Rhineland-Palatinate.

Further Information

Presentation on late effects of a SARS-CoV-2 infection at the press conference on December 20, 2021