Visual Universitätsmedizin Mainz

Selected Publications



  • Nicolas Ruffini, Susanne Klingenberg, Susann Schweiger and Susanne Gerber. Common Factors in Neurodegeneration: A Meta-Study revealing Shared Patterns on a Multi-Omics Scale, Cells 9(12), 2642,, (2020)
  • Monika Chongtham, Hristo Todorov, J.E. Wettschereck, Susanne Gerber and Jennifer Winter. Isolation of nuclei and downstream processing of cell-type-specific nuclei from micro-dissected mouse brain regions – techniques and caveats. bioRxiv, doi(2020)
  • Susanne Gerber, Lukas Pospisil, Mohit Navandar and Illia Horenko:Low-cost scalable discretization, prediction and feature selection for complex systems, Science Advances, Vol. 6, no. 5, eaaw0961 DOI: 10.1126/sciadv.aaw0961 (2020).
  • Laura Domingo-Rodriguez, Inigo Ruiz de Azua, Eduardo Dominguez, Eric Senabre, Irene Serra,Sami Kummer, Mohit Navandar, Sarah Baddenhausen, Clementine Hofmann, Raul Andero, Susanne Gerber, Marta Navarrete, Mara Dierssen, Beat Lutz, Elena Martín-García & Rafael Maldonado: A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction. Nature Communications 11, 782 (2020).
  • Caroline Fischer, Heiko Endle, Lana Schumann, Annett Wilken-Schmitz, Julia Kaiser, Susanne Gerber, Christina F. Vogelaar, Mirko H.H. Schmidt, Robert Nitsch, Isabel Snodgrass, Dominique Thomas, Johannes Vogt, Irmgard Tegeder. Prevention of age-associated neuronal hyperexcitability with improved learning and attention upon knockout or antagonism of LPAR2. Cellular and Molecular Life Sciences (2020).
  • Klytaimnistra Kiouptsi, Giulia Pontarollo, Hristo Todorov, Johannes Braun, Sven Jäckel, Thomas Koeck, Franziska Bayer, Cornelia Karwot, Angelica Karpi, Susanne Gerber, Yvonne Jansen, Philipp Wild, Wolfram Ruf, Andreas Daiber, Emiel van der Vorst, Christian Weber, Yvonne Döring, Christoph Reinhardt. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice.  Gut Microbes (2020).
  • Malena dos Santos Guilherme, Hristo Todorov, Carina Osterhof, Anton Möllerke, Kristina Cub, Thomas Hankeln, Susanne Gerber, Kristina Endres: Impact of acute and chronic amyloid-β peptide exposure on gut microbial commensals in the mouse.  Frontiers in Microbiology 11:1008. doi: 10.3389/fmicb.2020.01008 (2020).
  • Hristo Todorov, Emily Searle-White and Susanne Gerber. Applying univariate vs. multivariate statistics to investigate therapeutic efficacy in (pre)clinical trials: A Monte Carlo simulation study on the example of a controlled preclinical neurotrauma trial. PLOS ONE, 15(3): e0230798; (2020).
  • Hristo Todorov, Bettina Kollar, Franziska Bayer, Inês Brandão, Amrit Mann, Julia Mohr, Giulia Pontarollo, Henning Formes, Roland Stauber, Jens M. Kittner, Kristina Endres, Bernhard Watzer, Wolfgang Andreas Nockher, Felix Sommer, Susanne Gerber and Christoph Reinhardt. Alpha-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine. Nutrients. 12, 732; doi:10.3390/nu12030732. (2020).
  • Marlon Wendelmuth, Michael Willam, Hristo Todorov, Konstantin Radyushkin, Susanne Gerber and Susann Schweiger. Dynamic longitudinal behavior in animals exposed to chronic social defeat stress.  PLOS ONE. 15(7): e0235268 (2020).


  • Klytaimnistra Kiouptsi, Sven Jäckel, Giulia Pontarollo, Alexandra Grill, Marijke Kuijpers, Eivor Wilms, Christian Weber, Felix Sommer, Magdolna Nagy, Carlos Neideck, Yvonne Jansen, Stefanie Ascher, Henning Formes, Cornelia Karwot, Franziska Bayer, Bettina Kollar, Saravanan Subramaniam, Michael Molitor, Philip Wenzel, Philip Rosenstiel, Hristo Todorov, Susanne Gerber, Ulrich Walter, Kerstin Jurk, Johan Heemskerk, Emiel van der Vorst, Yvonne Döring, and Christoph Reinhardt: The microbiota promotes arterial thrombosis in low-density lipoprotein receptor-deficient mice. mBio, 10 (5) e02298-19; DOI: 10.1128/mBio.02298-19 (2019).
  • Charlotte Hewel, Julia Kaiser, Anna Wierczeiko, Jan Linke, Christoph Reinhardt, Kristina Endres and Susanne Gerber: Common miRNA patterns of Alzheimers disease and Parkinsons disease and their putative impact on commensal gut microbiota. Frontiers in Neuroscience, doi: 10.3389/fnins.2019.00113  (2019)


  • Susanne Gerber, Simon Olsson, Frank Noe and Illia Horenko: A scalable approach to the computation of invariant measures for high-dimensional Markovian systems. Nature Scientific Reports, 8,  Article number: 1796, doi:10.1038/s41598-018-19863-4 (2018)
  • Hristo Todorov, David Fournierand Susanne Gerber: Principal components analysis: theory and application to gene expression data analysis, Genomics and Computational Biology,  4(2) p. e100041, jan. 2018. ISSN 2365-7154 (2018)
  • Anna Wierczeiko, David Fournier, Hristo Todorov, Susanne Klingenberg, Kristina Endres and Susanne Gerber: Decoupling of DNA methylation status and gene expression levels in aging individuals,  Genomics and Computational Biology, 4(2) p.e100040, jan. 2018. ISSN 2365-7154 (2018).
  • Stanislav J. Sys, David Fournier, Illia Horenko, Kristina Endres and Susanne Gerber: Dynamics of SNP associations in relation to Alzheimer’s Disease captured with a new measure of linkage disequilibrium. Genomics and Computational Biology, 4(2) p. e100045, jan. 2018. ISSN 2365-7154 (2018).


  • Susanne Gerber and Illia Horenko: Towards a direct and scalable identification of reduced models for categorical processes, Proceedings of the National Academy of Sciences of the United States of America - (PNAS),114 (19) 4863-4868,doi:10.1073/pnas.1612619114 (2017).
  • Susanne Gerber, Martina Fröhlich, Hella Lichtenberg-Fraté, Sergey Shabala, Lana Shabala and Edda Klipp:  A Thermodynamic Model of Monovalent Cation Homeostasis in the Yeast Saccharomyces cerevisiae PLoS Comput. Biol. 12 (1), e1004703. doi: 10.1371/journal.pcbi.1004703, PMID: 26815455  (2016).
  • Susanne Gerber and Illia Horenko:  Improving clustering by imposing network information. Science Advances 1(7), e1500163; DOI: 10.1126/sciadv.1500163  (2015).
  • Susanne Gerber and Illia Horenko: On inference of causality for discrete state models in multiscale context.  Proceedings of the National Academy of Sciences of the United States of America -  111 (41) 14651-14656, doi:10.1073/pnas.1410404111,(2014).

Full list of publications: