DRUCKEN

2013

Heylmann D., Bauer M., Becker H., van Gool S., Bacher N., Steinbrink K.,  Kaina B. (2013) Human CD4+CD5+ regulatory T cells are sensitive to low dose cyclophosphamide: implications for the immune response, PLoS One, 8, e83384

 

Christow H., Lillich M., Sold A., Fahrer J., Barth H. (2013) Recombinant streptavidin-C3bot for delivery of proteins into macrophages, Toxicon, 75, 144-147


Ng D.Y., Fahrer J., Wu Y., Eisele K., Kuan S.L., Barth H., Weil T. (2013) Efficient delivery of p53 and cytochrome C by supramolecular assembly of a dendritic multi-domain delivery system, Advanced Healthcare Materials, 2, 1620-1629


Cabezas-Wallscheid N., Eichwald V., de Graaf J., Löwer M., Lehr H.A., Kreft A., Eshkind L., Hildebrandt A., Abassi Y., Heck R., Dehof A.K., Ohngemach S., Sprengel R., Wörtge S., Schmitt S., Lotz J., Meyer C., Kindler T., Zhang D.E., Kaina B., Castle J.C., Trumpp A., Sahin U., Bockamp E. (2013) Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model, EMBO Molecular Medicine5, 1804-1820

 

Eich M., Roos W.P., Nikolova T., Kaina B. (2013) Contribution of ATM and ATR to the resistance of the glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide, Molecular Cancer Therapeutics, 12, 2529-2540


Fahrer J., Kaina B. (2013) O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer, Carcinogenesis34, 2435-2442

 

Christmann, M., Kaina B. (2013) Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation, Nucleic Acids Research, 41, 8403-8420

 

Faust D., Kletting S., Ueberham E., Dietrich C. (2013) Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells, Toxicology Letters, 223, 73-80

Kosan C., Ginter T., Heinzel T., Krämer O. H. (2013) STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis, JAKSTAT, 2, e26102

 

Shehata M., Durner J., Eldenez A., Van Landuyt K., Styllou P., Rothmund L., Hickel R., Scherthan H., Geurtsen W., Kaina B., Carell T., Reichl F. X. (2013) Cytotoxicity and induction of DNA double-strand breaks by components leached from dental composites in primary human gingival fibroblasts, Dental Materials, 29, 971-979

 

Fahrer, J., Rausch J., Barth H. (2013) A cell-permeable fusion protein based on Clostridium botulinum C2 toxin for delivery of p53 tumor suppressor into cancer cells, PLoS One, 8, e72455

 

Hristova R., Hadjidekova V., Grigorova M., Nikolova T., Bulanova M., Popova L., Staynova A.,  Benova D. (2013) Chromosome analysis of nuclear power plant workers using fluorescence in situ hybridization and Giemsa assay, Journal of Radiation Research54, 832-839


Fritz, G., Kaina B. (2013) Rac1 GTPase, a multifunctional player in the regulation of genotoxic stress response, Cell Cycle, 12, 2521-2522

 

Tomicic M.T., Aasland D., Nikolova T., Kaina B., Christmann M. (2013) Human three prime exonuclease TREX1 is induced by genotoxic stress and involved in protection of glioma and melanoma cells to anticancer drugs, Biochimica et Biophysica Acta, 1833, 1832-1843

 

Hinterleitner C., Huelsenbeck J., Henninger C. (2013) Rac1 signaling protects monocytic AML cells expressing the MLL-AF9 oncogene from caspase-mediated apoptotic death, Apoptosis18, 963-979

 

Korfei M., von der Beck D., Henneke I., Markart P., Ruppert C., Mahavadi P., Ghanim B. ,Klepetko W., Fink L., Meiners S., Krämer O.H., Seeger W., Vancheri C., Guenther A. (2013) Comparative proteome analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP) and organ donors, Journal of Proteomics, 85, 109-128

Roos W.P., Kaina B. (2013) DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis, Cancer Letters332, 237-248


Faust D., Vondráček J., Krčmář P., Smerdová L., Procházková J., Hrubá E., Hulinková P., Kaina B., Dietrich C., Machala M. (2013) AhR-mediated changes in global gene expression in rat liver progenitor cells, Archives of Toxicology, 87, 681-698


Krämer O.H., Stauber R.H., Bug G., Hartkamp J., Knauer S.K. (2013) SIAH proteins: critical roles in leukemogenesis, Leukemia27, 792-802


Fahrer J., Schweitzer B., Fiedler K., Langer T., Gierschik P., Barth H. (2013) C2-streptavidin mediates the delivery of biotin-conjugated tumor suppressor protein p53 into tumor cells, Bioconjugate Chemistry24, 595-603


Thomas A.D., Jenkins G.J., Kaina B., Bodger O.G., Tomaszowski K.H., Lewis P.D., Doak S.H., Johnson G.E. (2013) Influence of DNA repair on nonlinear dose-responses for mutation, Toxicological Sciences, 132, 87-95

 

Bopp A., Wartlick F., Henninger C., Kaina B., Fritz G. (2013) Rac1 modulates acute and subacute genotoxin-induced hepatic stress responses, fibrosis and liver aging, Cell Death & Disease, 4, e558


Krost C., Petersen R., Lokan S., Brauksiepe B., Braun P., Schmidt E.R. (2013) Evaluation of the hormonal state of columnar apple trees (Malus x domestica) based on high throughput gene expression studies, Plant Molecular Biology, 81, 211-220


Tomicic M.T., Kaina B. (2013) Topoisomerase degradation, DSB repair, p53 and IAPS in cancer cell resistance to camptothecin-like topoisomeras I inhibitors, Biochimica et Biophysica Acta, 1835, 11-27

 

Knizhnik A.V., Roos W.P., Nikolova T., Quiros S., Tomaszowski K.H., Christmann M., Kaina B. (2013) Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage, PLoS One, 8, e55665

 

Popp O., Veith S., Fahrer J., Bohr V.A., Bürkle A., Mangerich A. (2013) Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions, ACS Chemical Biology, 8, 179-188