DRUCKEN

2011

Bauer M., Goldstein M., Christmann M., Becker H., Heylmann D., Kaina B. (2011) Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress, Proceedings of the National Academy of Sciences of the USA, 108, 21105-21110

 

Christmann M., Verbeek B., Roos W.P., Kaina B. (2011) O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry, Biochem Biophys Acta, 1816, 179-190

 

Efferth T., Kaina B. (2011) Toxicities by herbal medicines with emphasis to traditional Chinese medicine, Current Drug Metabolism, 12, 989-996

 

Dietrich C. (2011) The AHR in the control of cell cycle and apoptosis, in the AH receptor in Biology and Toxicology, (ed R. Pohjanvirta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140574.ch32

 

Frank H., Funk M., Oesch F., Platt K.L. (2011) Synthesis, absolute configuration, and bacterial mutagenicity of the 8 stereoisomeric vicinal diol epoxides at the terminal benzo ring of carcinogenic dibenz[a,h]anthracene, Chemical Research in Toxicology, 24, 2258-2268

 

Berdelle N., Nikolova T., Quiros S., Efferth T., Kaina B. (2011) Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells, Molecular Cancer Therapeutics10, 2224-2233

 

Quiros S., Roos W.P., Kaina B. (2011) Rad51 and BRCA2 – New molecular targets for sensitizing glioma cells to alkylating anticancer drugs, PLoS ONEDOI: 10.1371/journal.pone.0027183


Hamalukic M., Huelsenbeck J., Schad A., Wirtz S., Kaina B., Fritz G. (2011) Rac-1 regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors, Plos One6:e26413

 

Reichert S., Rödel C., Mirsch J., Harter P.N., Tomicic M.T., Mittelbronn M., Kaina B., Rödel F. (2011) Survivin inhibition and DNA double-strand break repair: A molecular mechanism to overcome radioresistance in glioblastoma, Radiotherapy and Oncology, 101, 51-58

 

Olsen B.B., Fischer U., Rasmussen T.L., Montenarh M., Meese E., Fritz G., Issinger O.G. (2011) Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2 a' levels, Molecular and Cellular Biochemistry356, 139-147

 

Hülsenbeck J., Henninger C., Schad A., Lackner K.J., Kaina B., Fritz G. (2011) Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity, Cell Death Disease 2:e190

 

Cimbora-Zovko T., Brozovic A., Piantanida I., Fritz G., Virag A., Alic B., Majce V., Kocevar M., Polanc S., Osmak M. (2011) Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agents, European Journal of Medicinal Chemistry46, 2971-2983

 

Roos W.P., Jöst E., Belohlavek C., Nagel G., Fritz G., Kaina B. (2011) Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by interferon-ß and valproic acid, Cancer Research71, 4150-4160

 

Kaina B., Christmann M. (2011) DNA-Schadensantwort und ihre pharmakologische Beeinflussung / DNA damage response and its pharmacological inhibition, Der Onkologe, 17, 503-512

 

Tomicic M.T., Reischmann P., Rasenberger B., Meise R., Kaina B., Christmann M. (2011) Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity, Cellular and Molecular Life Sciences68, 1785-1798

 

Nilsson S., Hülsenbeck J., Fritz G. (2011) Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells, Cancer Letters304, 60-69

 

Helbig L., Damrot J., Hülsenbeck J., Köberle B., Brozovic A., Osmak M., Fiket Z., Kaina B., Fritz G. (2011) Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells, Journal of Biological Chemistry286, 12991-13001

 

Küppers M., Faust D., Linz B., Dietrich C. (2011) Regulation of ERK1/2 activity upon contact inhibition in fibroblasts, Biochemical and Biophysical Research Communications406, 483-487

 

Wiese C., Nikolova T., Zahanich I., Sulzbacher S., Fuchs J., Yamanaka S., Graf E., Ravens U., Boheler K.R., Wobus A.M. (2011) Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin, International Journal of Cardiology147, 95-111

 

Fritz G., Henninger C., Hülsenbeck J. (2011) Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents, British Medical Bulletin97, 17-26


Sciuscio D., Diserens A.C., van Dommelen K., Martinet D., Jones G., Janzer R.C., Pollo C., Hamou M.F., Kaina B., Stupp R., Levivier M., Hegi M.E. (2011) Extent and patterns of MGMT promoter methylation in glioblastoma and respective derived spheres, Clinical Cancer Research, 17, 255-266


Dietrich C. (2011) Dioxin, persistentes risiko: wirkungen und mechanismen von dioxin, Labor&More, 1.11, 33-35

 

 

Christmann M., Kaina B. (2011) O6-Methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy, (Buchbeitrag).