DRUCKEN

2016

Herrtwich L., Nanda I., Evangelou K., Nikolova T., Horn V., Sagar, Erny D., Stefanowski J., Rogell L., Klein C., Gharun K., Follo M., Seidl M., Kremer B., Münke N., Senges J., Fliegauf M., Aschman T., Pfeifer D., Sarrazin S., Sieweke M., Wagner D., Dierks C., Haaf T., Ness T., Zaiss M., Voll R., Deshmukh S., Prinz M., Goldmann T., Hölscher C., Hauser A., Lopez-Contreras A., Grün D., Gorgoulis V., Diefenbach A., Henneke P., Triantafyllopoulou A. (2016) DNA damage signaling instructs polyploid macrophage fate in granulomasCell, 167, 1264-1280

 

Zahnreich S., Ebersberger A., Karle H., Kaina B., Schmidberger H. (2016) Quantification of radiation biomarkers in leukocytes of breast cancer patients treated with different modalities of 3D-CRT or IMRTRadiation Research, 186, 508-516 

 

Christmann M., Kaina B. (2016) MGMT - A critical DNA repair gene target for chemotherapy resistance, in 2nd edition, M.R. Kelley and M.L. Fishel (edts), DNA Repair in Cancer TherapyMolecular Targets and Clinical Applications, 55-82

 

Dietrich, C. (2016) Antioxidant functions of the aryl hydrocarbon receptorHindawi Publishing Corporation, Stem Cells International, volume 2016, 1-10

 

Roos W., Krumm A. (2016) The multifaceted influence of histone deacetylases on DNA damage signalling and DNA repair, Nucleic Acids Research, 44, 10017-10030

 

Fahrer J., Kaina B. (2016) Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens, Food and Chemical Toxicology, in press

 

Christmann M., Boisseau C., Kitzinger R., Berac C., Allmann S., Sommer T., Aasland D., Kaina B., Tomicic M. (2016) Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutationsNucleic Acids Research, 44, 10727-10743

 

Kaina B. (2016) DNA repair in cancer therapy with methylating anticancer drugs: improving therapeutic efficacy and reducing side effects, Carcinogenesis, Teratogenesis and Mutagenesis, 28, 333-347

 

Berte N., Piée-Staffa A., Piecha N., Wang M., Borgmann K., Kaina B., Nikolova T. (2016) Targeting homologous recombination by pharmacological inhibitors enhances the killing response of glioblastoma cells treated with alkylating drugsMolecular Cancer Therapeutics, 15, 2665-2678

 

Berte N., Lokan S., Eich M., Kim E., Kaina B. (2016) Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence, Oncotarget, 7, 67235-67250

 

Mimmler M., Peter S., Kraus A., Stroh S., Nikolova T., Seiwert N., Hasselwander S., Neitzel C., Haub J., Monien B., Nicken P., Steinberg P., Shay J., Kaina B., Fahrer J. (2016) DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP, Nucleic Acids Research, 44, 10259-10276

 

Fahrer J., (2016) Food-borne carcinogensEncyclopaedia of Cancer, M. Schwab (ed.), Springer Verlag Berlin-Heidelberg (Buchkapitel), DOI 10.1007/978-3-642-27841-9_7235-1

 

Mikhed Y., Fahrer J., Oelze M., Kröller-Schön S., Steven S., Welschof P., Zinßius E., Stamm P., Kashani F., Roohani S., Kress J., Ullmann E., Tran L., Schulz E., Epe B., Kaina B., Münzel T., Daiber A. (2016) Nitroglycerin induces DNA damage and vascular cell death in the setting of nitrate toleranceBasic Research in Cardiology, 111:52,  DOI: 10.1007/s00395-016-0571-4

 

Ebert F., Thomann M., Witt B., Müller S., Meyer S., Weber T., Christmann M., Schwerdtle T. (2016) Evaluating long-term cellular effects of the arsenic species thio-DMAV: qPCR-based gene expression as screening tool, Journal of Trace Elements in Medicine and Biology, 37, 78-84

 

Allgayer J., Kitsera N., Bartelt S., Epe B., Khobta A. (2016) Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine, Nucleic Acids Research, 44, 7267-7280

 

Krumm A., Barckhausen C., Kücük P., Tomaszowski K., Loquai C., Fahrer J., Krämer O., Kaina B., Roos W. (2016) Enhanced Histone Deacetylase activity in malignant melanoma provokes RAD51 and FANCD2-triggered drug resistanceCancer Research, 76, 3067-3077

 

Switzeny O., Christmann M., Renovanz M., Giese A., Sommer C., Kaina B. (2016) MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response, Clinical Epigenetics, 8:49, DOI 10.1186/s13148-016-0204-7

 

Motzek A., Knezevic J., Switzeny O., Cooper A., Baric I., Beluzic R., Strauss K., Puffenberger E., Mudd S., Vugrek O., Zechner U. (2016) Abnormal hypermethylation at imprinting control regions in patients with S-Adenosylhomocysteine hydrolase (AHCY) deficiency, Plos One11:e0151261

 

Heylmann D., Kaina B. (2016) The γH2AX DNA damage assay from a drop of bloodScientific Reports, 6:22682

 

Faust D., Nikolova T., Wätjen W., Kaina B., Dietrich C. (2016) The Brassica-derived phytochemical indolo [3,2-b] carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation, Archives of Toxicology, in press 

 

Roos W. P., Thomas A.D., Kaina B. (2016) DNA damage and the balance between survival and death in cancer biologyNature Reviews Cancer, 16, 20-33

 

Dörsam B., Fahrer J. (2016) The disulfide compound α-lipoic acid and its derivatives: a novel class of anticancer agents targeting mitochondriaCancer Letters, 371, 12-19

 

Sonnemann J., Kahl M., Siranjeevi M., Blumrich A., Blümel L., Becker S., Wittig S., Winkler R., Krämer O., Beck J. (2016) Reverse chemomodulatory effects of the SIRT1 activators resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity,  Cancer Research and Clinical Oncology 142, 17-26