DRUCKEN

2017

Kaowinn S., Won Jun S., Seok Kim C., Shin D.-M., Hwang Y.-H., Kim K., Shin B., Kaewpiboon C., Hee Jeong H., Seok Koh S., Krämer O.H., Johnston R.N., Chung Y.-H. (2017) Increased EGFR Expression induced by a novel oncogene, CUG2, confers resistance to doxorubicin through Stat1-HDAC4 signaling   Cell Oncol. (Pdf , 9,0 MB)  (8.8 MB) s13402-017-0343-7

 

Mahendrarajah N., Borisova M.E., Reichardt S., Godman M., Sellmer A., Mahboobi S., Haitel A., Schmid K. Kenner L., Heinzel T., Beli P., Krämer O.H. (2017)  HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3  Cellular Signalling   (Pdf , 1,0 MB)  (1018 KB)39 9-17 

    

Tomaszowski K.-H., Hellmann N., Takatsu H., Shin H.-W., Kaina B. (2017) Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases  Scientific Reports (Pdf , 1,5 MB)  (1.5 MB) in press

 

Christmann M., Kaina B. (2017) Epigenetic regulation of DNA repair genes an implications for Tumor therapy  Mutation Research-Reviews in Mutation Reseach (Pdf , 1,1 MB)  (1.0 MB) in press

 

Wenz C., Faust D., Linz B., Turmann C., Nikolova T., Bertin J., Gough P., Wipf P., Schröder A.S., Krautwald S., Dietrich C. (2017) t-BuOOH induces ferroptosis in human and murine cell lines  Arch Toxicol (Pdf , 1,7 MB)  (1.7 MB) in press

 

Kaina B. (2017) DNA und Darmkrebs: Wie Escheria coli und Darmzellen sich vor Genotoxinen schützen  Naturwissenschaftliche Rundschau (Pdf , 1,3 MB)  (1.2 MB)7 328-335

 

Seiwert N., Neitzel C., Stroh S., Frisan T., Audebert M., Toulany M., Kaina B., Fahrer J (2017) AKT2 suppresses pro survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells  Cell Death and Disease (Pdf , 3,4 MB)  (3.3 MB)8,e3019

 

Nikolova T., Kiweler N., Krämer O.H. (017) Interstrand Crosslink Repair as a Target for HDAC Inhibition Review Trends in Pharmacological Sciences in Press

 

Nikolova T., Marini ., Kaina B. (2017) Genotoxicity testing: Comparison of the γH2AX focus assay with te alkaline and neutral comet assays  Mutation Research - Genetic Toxikology and Environmental Mutagenesis Elsevier (Pdf , 850,5 KB)  (850 KB) 1383-5718

 

Fahrer J., Kaina B. (2017)  Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carciogens  Food and Chemical Toxicology Elsevier (Pdf , 1,7 MB)  (1.7 MB)0278-6915

 

Kitsera N., Allgayer J., Parsa E., Geier N., Rossa M., Carell T., Khobta A. (2017) Functional Impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter Nucleic Acids Research 1-13, in press

 

Mertsch S., Krämer OH. (2017) The interplay between histone deacetylase and rho kinases is important for cancer and neurodegeneration,  Elsevier (Pdf , 2,6 MB)  (2.6 MB)

 

Stojanovic N., Hassan Z., Wirth M., Wenzel P., Beyer M., Schäfer C., Brand P., Kroemer A., Stauber RH., Schmid RM., Arlt A., Sellmer A., Mahboobi S., Rad R., Reichert M., Saur D., Krämer OH., Schneider G.(2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer,  Oncogene (Pdf , 2,6 MB)  (2.5 MB), 36:1804-1815

 

Schäfer C., Göder A., Beyer M., Kiweler N., Mahendrarajah N., Rauch A.,  Nikolova T., Stojanovic N., Wieczorek M., Reich TR., Tomicic MT., Linnebacher M., Sonnemann J., Dietrich S., Sellmer A., Mahboobi S., Heinzel T., Schneider G., Krämer OH. 2017 Class I histone deacetylases regulate p53/NF-kappaB crosstalk in cancer cells,  Elsevier (Pdf , 1,3 MB)  (1.3 MB), 29:218-225

 

Freund P., Kerenyi MA., Hager M., Wagner T., Wingelhofer B., Pham HTT., Elabd M., Han X., Valent P., Gouilleux F., Sexl V., Krämer OH., Groner B., Moriggl R., O-GlcN Acylation of STA5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies,  Leukemia (Pdf , 3,3 MB)  (3.3 MB), 1-11

 

Noack K., Mahendrarajah N., Hennig D., Schmidt L., Grebien F., Hildebrand D., Christmann M., Kaina B., Sellmer A., Mahboobi S., Kubatzky K., Heinzel T., Krämer OH. (2017) Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells,  Arch Toxicol (Pdf , 1,3 MB)  (1.3 MB), 91: 2191-2208

 

Wetzel F., Mittag S., Cano-Cortina M., Wagner T., Krämer O.H., Niedenthal R., Gonzales-Mariscal L., Huber O. (2017) SUMOylation regulates the intracellular fate of ZO-2,  Cellular an Molecular Life Sciences (Pdf , 4,1 MB)  (4.0 MB) , 74:373-392  

 

Ponath V., Kaina B. (2017) Death of monocytes through oxidative burst of macrophages and neutrophils: killing in trans,  PLoS ONE (Pdf , 3,4 MB)  (3.3 MB), 12(1):e0170347,  1-20


Schäfer C., Göder A., Beyer M., Kiweler N., Mahendrarajah M., Rauch A., Nikolova T., Stojanovic N., Wieczorek M., Reich T., Tomicic M., Linnebacher M., Sonnem,ann J., Dietrich S., Sellmer A., Mahboobi S., Heinzel T., Schneider G., Krämer O.H. (2017) Class I histone deacetylases regulate p53/NF-kB crosstalk in cancer cells,  Cellular Signalling  (Pdf , 1,3 MB)  (1.3 MB)29, 218-225
 

Krumm A., Roos W. (2017) Assessing the effect of class I histone deacethylase activity on DNA double-strand break repair by homologous recombination, chapter 9, in Oliver H. Krämer (ed.),   HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols (Pdf , 13,6 MB)  (13.3 MB), Methods in Molecular biology, Springer Science Media, New York, 115-123

 

Nikolova T., Göder A., Parplys A., Borgmann K. (2017) DNA fiber spreading assay to test HDACi effects on DNA and its replication, chapter 8, in Oliver H. Krämer (ed.), HDAC /HAT Function Assessment and Inhibitor Development: Methods and Protocols, Methods in Molecular Biology, Springer Science Media, New York, 103-113

 

Reich Thomas R., Switzeny Olivier J., Renovanz M., Sommer C., Kaina B., Christmann M., Tomicic Maja T. (2017) Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome,  Oncotarget (Pdf , 2,0 MB)  (1.9 MB), 1-14

 

Fahrer J., Kaina B. (2017) Chemische Kanzerogenese, Helmut Greim: Das Toxikologiebuch (1), Wiley-VCH Verlag, 151

 

Bergholz L. M., Subic-Wrana C., Heylmann D., Beutel M. E., Wiltink J., Kaina B. (2017) DNA damage in lymphocytes of patients suffering from complex traumatization, DNA Repair, in press

 

Nikolova T., Roos W.P., Krämer O.H., Strik H.M., Kaina B. (2017) Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling, Biochimica et Biophysica Acta, Elsevier, 29-39

 

Christmann M., Diesler K., Majhen D., Steigerwald C., Berte N., Freund H., Stojanovic N., Kaina B., Osmak M., Ambriovic-Ristov A., Tomicic M.T. (2016) Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair,  Oncotarget (Pdf , 10,0 MB)  (9.8 MB), 8:27754-27771

 

Faust D., Nikolova T., Wätjen W., Kaina B., Dietrich C. (2017) The Brassica-derived phytochemical indolo [3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation,   Arch. Toxicol   (Pdf , 941,0 KB)  (941 KB)91: 967-982