Visual Universitätsmedizin Mainz

Dr. Hiroyuki Abe

Hiroyuki Abe ist Postdoktorand im TIM seit 2018 und Arzt an der Niigata University in Japan.
Er erhielt seinen M.D. und Ph.D. an der Niigata University.
Seine Forschung konzentriert sich auf Leberfibrose, Leberkrebs und Gentherapie.
Seine in Molecular Therapy Nucleic Acids veröffentlichte Dissertation lautet „Effektive Prävention von Leberfibrose durch auf die Leber abzielende hydrodynamische Genzufuhr von Matrix-Metalloproteinasen-13 in einem Rattenleberfibrosemodell“.
Danach arbeitete er zwei Jahre als Gastroenterologe im Sado-Krankenhaus. Während dieser Zeit beteiligte er sich an diversen klinischen Forschungsprojekten.
Hiroyuki Abe wurde 2018 von der Niigata Prefectural Welfare Federation of Agricultural Cooperative für sein Auslandsstudium ausgezeichnet.


1. Takahashi S, Kamimura K, Abe H, Watanabe Y, Hayashi K, Mizuno K, Yamamoto T, Takeuchi M, Natsui M, Terai S. (2019) Multiple Endocrine Neoplasia Type1-Rerated Acute Pancreatisis. Pancreas. 48; e35-e38
2. Arao Y, Kamimura K, Ikemi M, Takaki M, Takahashi S, Seino S, Abe H, Kohisa J, Kato T, Ajioka Y, Terai S. (2019) A Rare Duodenal Carcinoma; A Case Report and Literature Review. Intern Med. 58; 1273-1278
3. Ogawa K, Kamimura K, Kobayashi Y, Abe H, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Hayashi K, Ikarashi S, Kohisa J, Tsuchida M, Aoyagi Y, Zhang G, Liu D, Terai S. (2017) Efficacy and Safety of Pancreas-Targeted Hydrodynamic Gene Delivery in Rats. Mol Ther Nucleic Acids. 9:80-88
4. Abe H, Kamimura K, Terai S. (2017) Drug-eluting beads in hepatocellular carcinoma. Therap Adv Gastroenterol. 10:337-338
5. Kamimura K, Kobayashi Y, Takahashi Y, Abe H, Kumaki D, Tokoo T, Kamimura H, Sakai N, Sakamaki A, Abe S, Takamura M, Kawai H, Yamagiwa S, Terai S. (2017) Tumor markers for early diagnosis for brain metastasis of hepatocellular carcinoma: A case series and literature review for effective loco-regional treatment. Cancer Biol Ther. 18:79-84
6. Watanabe Y, Kamimura K, Iwasaki T, Abe T, Takahashi S, Mizuno K, Takeuchi M, Eino A, Narita I, Terai S. (2016) Case of severe alcoholic hepatitis treated with granulocytapheresis. World J Clin Cases. 4:369-375
7. Yokoo T, Kamiumura K, Abe H, Kobayashi Y, Kanefuji T, Ogawa T, Goto R, Oda M, Suda T, Terai S. (2016) Liver-targeted hydrodynamic gene therapy :Recent advances in the tequinique. World J Gastroenterol. 22:8862-68
8. Ogawa K, Kamimura K, Mizuno K, Shinagwa Y, Kobayashi Y, Abe H, Watanabe Y, Takahashi S, Hayashi K, Yokoyama J, Takeuchi M, Kobayashi M, Yamagiwa S, Sato Y, Terai S. (2016) The Combination Therapy of Dissolution Using Carbonated Liquid and Endoscopic Procedure for Bezoars :Pragmatical and Clinical Review. Gastroenterol Res Pract. doi :10
9. Kobayashi Y, Kamimura K, Abe H, Yokoo T, Ogawa K, Shinagawa-Kobayashi Y, Goto R, Inoue R, Ohtsuka M, Miura H, Suda T, Tsuchida M, Aoyagi Y, Zhang G, Liu D, Terai S. (2016) Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery. Mol Ther Nucleic Acids. 5:e359
10. Kamimura K, Shinagawa Y, Ogawa K, Kobayashi Y, Abe H, Yokoo T, Kamimura H, Kawai H, Suda T, Yamagiwa S, Baba H, Terai S. (2016) Effective Prevention of Hand-Foot Syndrome by the Consumption of Dried Bonito Broth. Gan To Kagaku Ryoho.43 (4) :463-5
11. Abe H, Kamimura K, Kobayashi Y, Ohtsuka M, Miura H, Ohashi R, Yokoo T, Kanefuji T, Suda T, Tsuchida M, Aoyagi Y, Zhang G, Liu D, Terai S. (2016) Effective Prevention of Liver Fibrosis by Liver-targeted Hydrodynamic Gene Delivery of Matrix Metalloproteinases-13 in a Rat Liver Fibrosis Model. Mol Ther Nucleic Acids. 5:e276
12. Abe H, Kamimura K, Kawai H, Kamimura H, Domori K, Kobayashi Y, Nomoto M, Aoyagi Y. (2015) Diagnostic Imaging of Hepatic Lymphoma. Clin Res Hepatol Gastroenterol. 39:435-442
13. Kamimura K, Kumaki D, Arita M, Kobayashi Y, Mizuno K, Kusama F, Kobayashi M, Abe H, Takahashi Y, Ogawa K, Shinagawa Y, Takeuchi M, Sato Y, Kawai H, Yamagiwa S, Terai S. (2015) First Case of Bacteria Caused by Helicobacter Cinedi in a Patient with Liver Cirrhosis: A Case Report and Literature Review. Clin J Gastroenterol. 8:306-317
14. Kamimura K, Yokoo T, Abe H, Kobayashi Y, Ogawa K, Shinagawa Y, Inoue R, Terai S. (2015) Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions. Pharmaceutics. 7:213-223
15. Kamimura K, Abe H, Kawai H, Kamimura H, Kobayashi Y, Nomoto M, Aoyaghi Y, Terai S. (2015) Advances in Understanding and Treating Liver Diseases During Prengnancy: A Review. World J Gastroenterol. 21:5183-5190
16. Abe H, Kamimura K, Mamizu M, Shibazaki Y, Ishiguro T, Katada S, Nishiyama Y, Takahashi Y, Hatano Y, Mizuno K, Watanabe Y, Nagashima A, Takizawa J, Takeuchi M, Kawai H, Nomoto M, Sone H, Nishizawa M, Aoyagi Y. (2014) Early Diagnosis of Hepatic Intravasucular Lymphoma: A Case Report and Literature Review. Intern Med. 53:587-593
17. Abe H, Kamimura K, Yokoo T, Suda T, Kobayashi Y, Aoyagi Y. (2014) Gene Therapy for Liver Fibrosis. JSM Gastroenterol Hepatol. 2:1028
18. Kamimura K, Abe H, Kamimura N, Yamaguchi M, Mamizu M, Ogi K, Takahashi Y, Mizuno K, Kamimura H, Kobayashi Y, Takeuchi M, Yoshida K, Yamada K, Enomoto T, Takakuwa K, Nomoto M, Obata M, KAtsuragi Y, Mishima Y, Kominami R, Kamimura T, Aoyagi Y. (2014) Successful Management of Severe Intrahepatic Cholestasis of Pregnancy: Report of a First Japanese Case. BMC Gastroenterology. 14:160
19. Kamimura K, Kanefuji T, Yokoo T, Abe H, Suda T, Kobayashi Y, Zhang G, Aoyagi Y, Liu D. (2014) Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs. PLoS One. 9:e107203
20. Kamimura K, Abe H, Aoyagi Y. (2014) Alcoholic Liver Disease: A Review. Autstin J Gastroenterol. 1:3
21. Abe H, Ishikawa T, Nagashima A, Hirose K, Kubota T, Togashi T, Seki K, Honma T, Yoshida T, Kamimura T, Sato Y. (2013) A case of percutaneous transhepatic o bliteration for hepatic encephalopathy due to port-systemic shunt after Living Donor Liver Transplantation. Kanzo 54: 774-779.
22. Kamimura K, Abe H, Suda T, Aoyagi Y, Liu D. (2013) Liver-directed Gene Therapy. JSM Gastroenterology and Hepatology 1: 1005
23. Ishikawa T, Kubota T, Abe H, Toduka Y, Horigome R, Watanabe Y, Kimura N, Honda H, Iwanaga A, Seki K, Honma T, Yoshida T, Sato M. (2013) Case of cerebral lipiodol embolism after repeated transcatheter arterial chemoembolization of hepatocellular carcinoma. Hepatology Reseach 43: 1251-1252.
24. Ishikawa T, Kubota T, Abe H, Nagashima A, Hirose K, Seki K, Honma T, Yoshida T. (2013) Improved method for transjugular liver biopsy using imaging sheaths developed for balloon-occluded retrograde transvenous obliteration. Hepatogastroenterology 60:1684-1688
25. Ishikawa T, Kubota T, Abe H, Nagashima A, Hirose K, Togashi T, Seki K, Honma T, Yoshida T, Kamimura T. (2012) Efficacy of the regimen using twice-daily β-interferon followed by the standard of care for chronic hepatitis C genotype 1b with high viral load. Hepatology Reseach 42: 864-869.
26. Ishikawa T, Kubota T, Abe H, Nagashima A, Hirose K, Togashi T, Seki K, Honma T, Yoshida T, Kamimura T, Nemoto T, Takeda T, Ishihara N. (2012) Histopathology of the Tissue Adhering to the Multiple Tine Expandable Electrodes Used for Radiofrequency Ablation of Hepatocellular Carcinoma Predicts Local Recurrence. Internal Medicine 51: 2683-2688.