Publikationen von Prof. Dr. Beat Lutz

Publikationen 2022

Leschik J, Gentile A, Cicek C, Péron S, Tevosian M, Beer A, Radyushkin K, Bludau A, Ebner K, Neumann I, Singewald N, Berninger B, Lessmann V, Lutz B. Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis. Prog Neurobiol. 2022 Jul 21:102333.

De Giacomo V, Ruehle S, Lutz B, Häring M*, Remmers F*. Cell type-specific genetic reconstitution of CB1 receptor subsets to assess their role in exploratory behaviour, sociability, and memory. Eur J Neurosci. 2022 Feb;55(4):939-951. (*These authors share the last authorship.)

Post JM, Lerner R, Schwitter C, Lutz B, Lomazzo E, Bindila L. Lipidomics and Transcriptomics in Neurological Diseases. J Vis Exp. 2022 Mar 18;(181).

Decara JM, Vázquez-Villa H, Brea J, Alonso M, Srivastava RK, Orio L, Alén F, Suárez J, Baixeras E, García-Cárceles J, Escobar-Peña A, Lutz B, Rodríguez R, Codesido E, Garcia-Ladona FJ, Bennett TA, Ballesteros JA, Cruces J, Loza MI, Benhamú B, Rodríguez de Fonseca F, López-Rodríguez ML. Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity". J Med Chem. 2022 Apr 14;65(7):5449-5461.

Sánchez-de la Torre A#, Aguado T#, Huerga-Gómez A, Santamaría S, Gentile A, Chara JC, Matute C, Monory K, Mato S, Guzmán M, Lutz B, Galve-Roperh I, Palazuelos J. Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice. Cell Death Dis. 2022 Jul 7;13(7):585 (#equal contributions).

Srivastava RK, Lutz B, Ruiz de Azua I. The Microbiome and Gut Endocannabinoid System in the Regulation of Stress Responses and Metabolism. Front Cell Neurosci. 2022 May 11;16:867267.

Weisser S#, Mueller M#, Rauh J, Esser R, Fuss J, Lutz B, Haaker J. Acquisition of threat responses are associated with elevated plasma concentration of endocannabinoids in male humans. Neuropsychopharmacology 2022 May 13. (#equal contributions)

Zieglgänsberger W, Brenneisen R, Berthele A, Wotjak CT, Bandelow B, Tölle TR, Lutz B. Chronic Pain and the Endocannabinoid System: Smart Lipids - A Novel Therapeutic Option? Med Cannabis Cannabinoids. 2022 Mar 22;5(1):61-75.

Publikationen 2021

Pascual Cuadrado D#, Todorov H#, Lerner R, Islami L, Bindila L, Gerber S, Lutz B. Long-term molecular differences between resilient and susceptible mice after a single traumatic exposure. Br J Pharmacol. 2021 Oct 2. (# contributed equally)

Jene T, Ruiz de Azua I, Hasch A, Klüpfel J, Deuster J, Maas M, Nijboer CH, Lutz B, Müller MB, van der Kooij MA. Chronic social stress lessens the metabolic effects induced by a high-fat diet. J Endocrinol. 2021 Apr;249(1):19-30.

Ochmann DT, Philippi KFA, Zeier P, Sandner M, Hillen B, Neuberger EWI, Ruiz de Azua I, Lieb K, Wessa M, Lutz B, Simon P, Brahmer A. Association of Innate and Acquired Aerobic Capacity With Resilience in Healthy Adults: Protocol for a Randomized Controlled Trial of an 8-Week Web-Based Physical Exercise Intervention. JMIR Res Protoc 2021;10(11):e29712

Saumell-Esnaola M, Barrondo S, García del Caño G, Goicolea MA, Sallés J, Lutz B, Monory K. Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex. Molecules 2021; 26(22):6897.

Herzog DP, Pascual Cuadrado D, Treccani G, Jene T, Opitz V, Hasch A, Lutz B, Lieb K, Sillaber I, van der Kooij MA, Tiwari VK, Müller MB. A distinct transcriptional signature of antidepressant response in hippocampal dentate gyrus granule cells. Transl Psychiatry. 2021 Jan 5;11(1):4.

Ahrens KF*, Neumann RJ*, Kollmann B*, Brokelmann J, von Werthern NM, Malyshau A, Weichert D, Lutz B, Fiebach CJ, Wessa M, Kalisch R, Plichta MM, Lieb K*, Tüscher O*, Reif A* Impact of COVID-19 lockdown on mental health in Germany: longitudinal observation of different mental health trajectories and protective factors. Transl Psychiatry 2021 Jul 17;11(1):392. (*Contributed equally)

Chmitorz A#, Neumann RJ#, Kollmann B#, Ahrens KF, Öhlschläger S, Goldbach N, Weichert D, Schick A, Lutz B, Plichta MM, Fiebach CJ, Wessa M, Kalisch R, Tüscher O, Lieb K#, Reif A# Longitudinal determination of resilience in humans to identify mechanisms of resilience to modern-life stressors: the longitudinal resilience assessment (LORA) study. Eur Arch Psychiatry Clin Neurosci. 2020 Jul 18. (# Contributed equally)

Jehle J#, Eich L#, Danisch M, Bagheri S, Avraamidou E, Pfeifer P, Tiyerili V, Bindila L, Lutz B, Nickenig G The endocannabinoid 2-arachidonoylglycerol inhibits endothelial function and repair. Int J Cardiol 323:243-250. doi: 10.1016/j.ijcard.2020.08.042. (# contributed equally)

Kodirov SA, Bonni K, Wehrmeister M, Lutz B. Depolarization-initiated endogenous cannabinoid release and underlying retrograde neurotransmission in interneurons of amygdala. Learn Mem. 2021 Jan 15;28(2):44-52. 

Leschik J, Lutz B, Gentile A Stress-Related Dysfunction of Adult Hippocampal Neurogenesis-An Attempt for Understanding Resilience? Int J Mol Sci. 2021 Jul 8;22(14):7339. 

Milic M, Schmitt U, Lutz B, Müller MB Individual baseline behavioral traits predict the resilience phenotype after chronic social defeat. Neurobiol Stress. 2020 Dec 29;14:100290. 

Navandar M, Martín-García E, Maldonado R, Lutz B, Gerber S, Ruiz de Azua I  Transcriptional signatures in prefrontal cortex confer vulnerability versus resilience to food and cocaine addiction-like behavior. Sci Rep. 2021 Apr 27;11(1):9076.

Pascual Cuadrado D, Wierczeiko A, Hewel C, Gerber S, Lutz B. Dichotomic Hippocampal Transcriptome After Glutamatergic vs. GABAergic Deletion of the Cannabinoid CB1 Receptor. Front Synaptic Neurosci. 2021 Apr 8;13:660718. 

Preuss UW, Huestis MA, Schneider M, Hermann D, Lutz B, Hasan A, Kambeitz J, Wong JWM, Hoch E Cannabis Use and Car Crashes: A Review. Front Psychiatry 2021 May 28;12:643315. 

Ruiz de Azua I#, Martin-Garcia E#, Domingo-Rodriguez L, Aparisi Rey A, Pascual Cuadrado D, Islami L, Turunen P, Remmers F, Lutz B, Maldonado R Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons drives overconsumption of palatable food and obesity. Neuropsychopharmacology 2021 Apr;46(5):982-991. (^# Contributed equally)

Schuele LL, Glasmacher S, Gertsch J, Roggan MD, Transfeld JL, Bindila L, Lutz B, Kolbe CC, Bilkei-Gorzo A, Zimmer A, Leidmaa E. Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors. Glia 2021 Feb;69(2):377-391.

Siebers M, Biedermann SV, Bindila L, Lutz B, Fuss J Exercise-induced euphoria and anxiolysis do not depend on endogenous opioids in humans. Psychoneuroendocrinology 2021 Apr;126:105173.