Visual Universitätsmedizin Mainz

Resilience and prevention

Background

Around 120 million citizens in the European Union are affected by stress-related mental disorders every year. Stress resilience and stress prevention are becoming increasingly important in Western societies. The term "resilience" describes the ability of people during or after adverse life events to maintain or to recover their mental health. The aim is thus to strengthen resilience and thereby to avoid becoming mentally ill despite considerable mental or physical stress.

Projects

The following working groups deal with the topic of stress resilience and prevention in various projects:

Working groups in the Department for Psychiatry and Psychotherapy

Working groups at Leibniz-Institute for Resilience Research (LIR)

The following projects are being worked on in cooperation with the research groups Lieb, Tüscher, and Wiegand/Hölzel. They are part of the national network COVID-19 of the German University Medical Centers. 

Key publications

    • Oettl, L., Scheller, M., Filosa, C., Wieland S, Haag F., Loeb C., Durstewitz D., Shusterman R., Russo E., Kelsch W. (2020). Phasic dopamine reinforces distinct striatal stimulus encoding in the olfactory tubercle driving dopaminergic reward prediction. Nat Commun 11, 3460 (2020). https://doi.org/10.1038/s41467-020-17257-7
    • Hewel C., Kaiser J., Wierczeiko A., Linke J., Reinhardt C., Endres K., Gerber S. (2019). Common miRNA Patterns of Alzheimer's Disease and Parkinson's Disease and Their Putative Impact on Commensal Gut Microbiota. Front Neurosci. 13:113.
    • Brandscheid C., Schuck F., Reinhardt S., Schäfer K.H., Pietrzik C.U., Grimm M. Hartmann T., Schwiertz A., Endres K. (2017). Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model. J Alzheimers Dis. 56:775-788.
    • Oettl LL, Ravi N., Schneider M., Scheller M.F., Schneider P., Mitre M., Da Silva Gouveia M., Froemke R.C., Chao M.V. Young W.S., Meyer-Lindenberg A., grinevich V., Shustermann R., Kelsch W. (2016). Oxytocin Enhances Social Recognition by Modulating Cortical Control of Early Olfactory Processing. Neuron 90:609-21.

Funding

  • German Research Foundation (DFG)
  • Federal Ministry of Education and Research (BMBF)