Visual Universitätsmedizin Mainz

Dr. rer. nat. Danuta Galetzka

Dr. rer. nat. Galetzka
- Molekulargenetik
+49 (0) 6131 17-2860


Molecular karyotyping and gene expression analysis in childhood cancer patients. Galetzka D, Müller T, Dittrich M, Endres M, Kartal N, Sinizyn O, Rapp S, Zeller T, Müller C, Hankeln T, Scholz-Kreisel P, Chorzempa H, Mirsch J, Poplawski A, Rossmann H, Spix C, Haaf T, Prawitt D, Marron Manuela & Schmidberger Heinz.

J Mol Med (2020).

Homozygous variants in the gene SCAPER cause syndromic intellectual disability. Kahrizi K, Huber M, Galetzka D, Dewi S, Schröder J, Weis E, Kariminejad A, Fattahi Z, Ropers HH, Schweiger S, Najmabadi H, Winter J. Am J Med Genet A. 2019 Jul;179(7):1214-1225. doi: 10.1002/ajmg.a.61172. Epub 2019 May 9. PMID: 31069901

Abdalla E, Bartsch O, Galetzka D, Zechner U.: Novel clinical findings in the

first Egyptian case of Sotos syndrome caused by complete deletion of the NSD1

gene. Am J Med Genet A. 2017 Apr;173(4):1090-1093. doi: 10.1002/ajmg.a.38107.

Schneider E, Dittrich M, Bäck J, Nanda I, Müller T, Seidmann L, Tralau T,

Galetzka D, El Hajj N, Haaf T.: CpG sites with continuously increasing or

decreasing methylation from early to late human fetal brain development. Gene.

2016 Oct 30;592(1):110-118. doi: 10.1016/j.gene.2016.07.058. Epub 2016 Jul 25.

PubMed PMID: 27468947

El Hajj N, Dittrich M, Bäck J, Kraus TF, Nanda I, Müller T, Seidmann L, Tralau

T, Galetzka D, Schneider E, Haaf T.: Epigenetic dysregulation in the developing

Down syndrome cortex. Epigenetics. 2016 Aug 2;11(8):563-78. doi:

10.1080/15592294.2016.1192736. Epub 2016 May 31. PubMed PMID: 27245352; PubMed Central PMCID: PMC4990229

Etzold A, Galetzka D, Weis E, Bartsch O, Haaf T, Spix C, Itzel T, Schweiger S,

Strand D, Strand S, Zechner U.: CAF-like state in primary skin fibroblasts with

constitutional BRCA1 epimutation sheds new light on tumor suppressor

deficiency-related changes in healthy tissue. Epigenetics. 2016;11(2):120-31.

doi: 10.1080/15592294.2016.1140295. Epub 2016 Mar 7. PubMed PMID: 26949839;

PubMed Central PMCID: PMC4846144

Etzold A, Schröder JC, Bartsch O, Zechner U, Galetzka D. Further evidence for

pathogenicity of the TP53 tetramerization domain mutation p.Arg342Pro in

Li-Fraumeni syndrome. Fam Cancer. 2015 Mar;14(1):161-5. doi:

10.1007/s10689-014-9754-z. PubMed PMID: 25226867

Schröder JC, Läßig AK, Galetzka D, Peters A, Castle JC, Diederich S, Zechner U, Müller-Forell W, Keilmann A, Bartsch O.: A boy with homozygous microdeletion of NEUROG1 presents with a congenital cranial dysinnervation disorder [Moebius syndrome variant]. Behav Brain Funct. 2013 Feb 18;9:7

Victor A, Weis E, Messow CM, Marron M, Haaf T, Spix C, Galetzka D. Searching for gene expression differences in primary fibroblasts between patients with one and two neoplasms in childhood. Pediatr Hematol Oncol. 2013 Feb;30(1):33-45

Ziebart T, Draenert FG, Galetzka D, Babaryka G, Schmidseder R, Wagner W, Bartsch O.: The original family revisited after 37 years: odontoma-dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3, including the FGF3 and FGF4 genes. Clin Oral Investig. 2012 Feb 3

Danuta Galetzka, Tamara Hansmann, Nady El Hajj, Eva Weis, Benjamin Irmscher, Marco Ludwig, Brigitte Schneider-Rätzke, Nicolai Kohlschmidt,Vera Beyer, Oliver Bartsch, Ulrich Zechner, Claudia Spix and Thomas Haaf: Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer. Epigenetics. 2012 Jan 1;7(1)

Eva Weis, Holger Schoen, Anja Victor, Claudia Spix, Marco Ludwig, Brigitte Schneider-Raetzke, Nicolai Kohlschmidt, Oliver Bartsch, Aslihan Gerhold-Ay, Nils Boehm, Franz Grus, Thomas Haaf, and Danuta Galetzka: Reduced mRNA and Protein Expression of the Genomic Caretaker RAD9A in Primary Fibroblasts of Individuals with Childhood and Independent Second Cancer.PLoS One. 2011;6(10):e25750. Epub 2011 Oct

Schneider E, Pliushch G, El Hajj N, Galetzka D, Puhl A, Schorsch M, Frauenknecht K, Riepert T, Tresch A, Müller AM, Coerdt W, Zechner U, Haaf T.: Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns. Nucleic Acids Res. 2010; 38(12): 3880-3890

Haege S, Galetzka D, Zechner U, Haaf T, Gamerdinger M, Behl C, Hiemke C, Schmitt U.: Spatial learning and expression patterns of PP1 mRNA in mouse hippocampus. Neuropsychobiology. 2010;61(4):188-96

Damatova N, Beyer V, Galetzka D, Schneider E, Napiontek U, Keilmann A, Zechner U, Bartsch O, Haaf T.: Haploinsufficiency of 16.4 Mb from chromosome 22pter-q11.21 in a girl with unilateral conductive hearing loss. Cytogenet Genome Res. 2009;125(3):241-7. Epub 2009 Sep 4. PubMed

Weis E, Galetzka D, Herlyn H, Schneider E, Haaf T.: Humans and chimpanzees differ in their cellular response to DNA damage and non-coding sequence elements of DNA repair-associated genes. Cytogenet Genome Res. 2008;122(2):92-102. Epub 2008 Dec 18. PubMed PMID: 19096204

Galetzka D, Weis E, Rittner G, Schindler D, Haaf T.: Microarray mRNA expression analysis of Fanconi anemia fibroblasts. Cytogenet Genome Res. 2008;121(1):10-3. Epub 2008 May 7. PubMed PMID: 18544920

Ruf N, Bähring S, Galetzka D, Pliushch G, Luft FC, Nürnberg P, Haaf T, Kelsey G, Zechner U.: Sequence-based bioinformatic prediction and QUASEP identify genomic imprinting of the KCNK9 potassium channel gene in mouse and human. Hum Mol Genet. 2007 Nov 1;16(21):2591-9. Epub 2007 Aug 17

Buiting K, Nazlican H, Galetzka D, Wawrzik M, Gross S, Horsthemke B.: C15orf2 and a novel noncoding transcript from the Prader-Willi/Angelman syndrome region show monoallelic expression in fetal brain. Genomics. 2007 May;89(5):588-95. Epub 2007 Mar 6

Yue Y, Farcas R, Thiel G, Bommer C, Grossmann B, Galetzka D, Kelbova C, Küpferling P, Daser A, Zechner U, Haaf T.: De novo t(12;17)(p13.3;q21.3) translocation with a breakpoint near the 5' end of the HOXB gene cluster in a patient with developmental delay and skeletal malformations. Eur J Hum Genet. 2007 May;15(5):570-7. Epub 2007 Feb 28

Galetzka D, Weis E, Kohlschmidt N, Bitz O, Stein R, Haaf T.: Expression of somatic DNA repair genes in human testes. J Cell Biochem. 2007 Apr 1;100(5):1232-9

Galetzka D, Weis E, Tralau T, Seidmann L, Haaf T.: Sex-specific windows for high mRNA expression of DNA methyltransferases 1 and 3A and methyl-CpG-binding domain proteins 2 and 4 in human fetal gonads. Mol Reprod Dev. 2007 Feb;74(2):233-41

Yue Y, Grossmann B, Galetzka D, Zechner U, Haaf T.: Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice. Genomics. 2006 Dec;88(6):772-8. Epub 2006 Jul 10

Galetzka D, Tralau T, Stein R, Haaf T.: Expression of DNMT3A transcripts and nucleolar localization of DNMT3A protein in human testicular and fibroblast cells suggest a role for de novo DNA methylation in nucleolar inactivation. J Cell Biochem. 2006 Jul 1;98(4):885-94

Boonrod K, Chotewutmontri S, Galetzka D, Krczal G.: Analysis of tombusvirus revertants to identify essential amino acid residues within RNA-dependent RNA polymerase motifs. J Gen Virol. 2005 Mar;86(Pt 3):823-6

Boonrod K, Galetzka D, Nagy PD, Conrad U, Krczal G.: Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance. Nat Biotechnol. 2004 Jul;22(7):856-62. Epub 2004 Jun 13

D. Galetzka, M. Russo, L. Lubino, and G. Krczal: Molecular characterization of a Tombusvirus associated with a disease of Statice [Goniolimon Tataricum (L.) Boiss]. J. Plant Pathol., 82 (2), 151-155, (2000)

Suelmann R, Sievers N, Galetzka D, Robertson L, Timberlake WE, Fischer R.: Increased nuclear traffic chaos in hyphae of Aspergillus nidulans: molecular characterization of apsB and in vivo observation of nuclear behaviour. Mol Microbiol. 1998 Nov;30(4):831-42