The Else Kröner School for Medical Scientists “RNA-based therapeutic strategies in tumor immunology and immune-mediated diseases (TheRNAtics)" builds a bridge between (basic) scientific and clinically active researchers with a view to modern RNA-based immune and cancer therapies. Unique to TheRNAtik are the close ties between medical scientists and clinician scientists through the establishment of tandems in independent research projects. The Else Kröner School for Medical Scientists will be embedded in the comprehensive training environment, which TransMed has developed to meet the needs of its fellows. A solid foundation for the work of the fellows is provided by established structures of basic, translational and clinical research at UM Mainz. FZI, TRON, HI-TRON as well as IZKS offer an immense amount of know-how and a range of state-of-the-art technologies. In this optimal research environment, the fellows can contribute significantly to the basic scientific investigation of clinical questions. TheRNAtik is intended to set new qualitative and quantitative standards in the collaboration between medical scientists and clinician scientists, with the aim of opening up new therapeutic options for patients.