Professorship for Multicenter Clinical Trials

At the CTH, we design, coordinate and conduct academic multicenter clinical trials on thrombotic disorders in collaboration with our European and overseas partners. Our research focuses on advancing and optimizing the risk-adjusted management of venous thromboembolism (VTE).

In ongoing prospective randomized and cohort trials we are investigating:

• advanced reperfusion strategies, including reduced-dose systemic thrombolysis or catheter-directed pharmacomechanical thrombus removal, for risk-adapted treatment of acute severe (intermediate-high-risk) pulmonary embolism

• identification of patients with low-risk pulmonary embolism who may be candidates for early discharge and home treatment

• approoaches to secondary VTE prevention beyond chronic oral anticoagulation, with a focus on modifying the patient’s global cardiovascular risk profile

• reliable, cost-effective algorithms for patient follow-up after pulmonary embolism, aiming at the prevention or early detection of severe late sequelae

• innovative strategies for de-escalation of postoperative primary thromboprophylaxis in parallel to the progress in surgical techniques and early patient mobilization.

Beyond individual clinical research projects, the vision of the professorship for multicenter clinical trials at the CTH is to play a leading role in networking centers of excellence in the field of thrombosis and pulmonary embolism research.

We invite you to find more detailed information about our projects and trials on our dedicated website.

Do you have a biomedical background, and are you interested in participating in guidelines-relevant clinical research and thus helping to shape future clinical practice? If yes, feel free to contact us! We are looking forward to your application.
Stavros Konstantinides, MD Katharina Mohr (Phone +49 6131 17-8382)



Best regards,

Professor Stavros Konstantinides, MD
Medical Director of the CTH