Visual Universitätsmedizin Mainz

Publications 2017

Dehorter N, Marichal N, Marín O, Berninger B (2017). Tuning neural circuits by turning the interneuron knob. Current Opinion in Neurobiology, 42: 144-151

Publications 2016

Kleiderman S, Gutbier S, Tufekci KU, Ortega F, Sá JV, Teixeira AP, Brito C, Glaab E, Berninger B, Alves PM, Leist M (2016). Conversion of non-proliferating astrocytes into neurogenic neural stem cells: control by FGF2 and IFN-gamma. Stem Cells, 34: 2861-2874

McAvoy KM, Scobie KN, Berger S, Russo C, Guo N, Decharatanachart P, Ramirez H-V, Miake-Lye S, Whalen M, Nelson M, Bergami M, Bartsch D, Hen R, Berninger B, Sahay A (2016). Modulating neuronal competition dynamics in the dentate gyrus to rejuvenate aging memory circuits. Neuron 91: 1356-1373

Thakurela S, Tiwari N, Schick S, Garding A, Ivanek R, Berninger B, Tiwari VK (2016) Mapping gene regulatory circuitry of Pax6 during neurogenesis. Cell Discovery 2: 15045

Berninger B, Jessberger S (2016). Engineering of adult neurogenesis and gliogenesis. Cold Spring Harbor Perspectives in Biology, 8(5). pii: a018861

Sahu SK, Fritz A, Tiwari N, Kovacs Z, Pouya A, Wüllner V, Bora P, Schacht T, Baumgart J, Peron S, Berninger B, Tiwari VK, Methner A (2016) TOX3 regulates neural progenitor identity. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 1859: 833-840

Bunk EC, Ertaylan G, Ortega F, Pavlou MA, Cano LG, Stergiopoulos A, Safaiyan S, Völs S, van Cann M, Politis PK, Simons M, Berninger B, del Sol A, Schwamborn JC (2016) Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells 34: 2115-2129

Azim K, Berninger B, Raineteau (2016). Mosaic subventricular origins of forebrain oligodendrogenesis. Frontiers in Neuroscience, 10:107

Gascón S, Mureno E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Roberston SP, Schroeder T, Beckers J, Irmler M, Berndt C, Friedmann Angeli JP, Conrad M, Berninger B, Götz M (2016). Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming. Cell Stem Cell 18: 396-409

Publications 2015

Chen G, Wernig M, Berninger B, Nakafuku M, Parmar M, Zhang C-L (2015) In vivo reprogramming for brain and spinal cord repair. eNeuro, 2(5). pii: ENEURO.0106-15.2015

Péron S, Berninger B (2015) Previews: Imported stem cells strike against stroke. Cell Stem Cell 17: 501-502.

Aravantinou-Fatorou K, Ortega F, Chroni-Tzartou D, Antoniou N, Poulopoulou C, Politis PK, Berninger B, Matsas R, Thomaidou D (2015) Cend1 and neurogenin2 reprogram mouse astrocytes and embryonic fibroblasts to induced neural precursors and differentiated neurons. Stem Cell Reports 5: 405-418

Péron S, Berninger B (2015) Reawakening the Sleeping Beauty in the adult brain: neurogenesis from parenchymal glia. Current Opinion in Genetics & Development 34: 46-53

Sahu SK, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M, Tiwari VK (2015) JNK-dependent gene regulatory circuitry governs mesenchymal fate. The EMBO Journal 34: 2162-2181

Masserdotti G, Gillotin S, Sutor B, Drechsel D, Irmler M, Jørgensen HF, Sass S, Theis FJ, Beckers J, Berninger B, Guillemot F, Götz M (2015) Transcriptional mechanisms of proneural factors and REST in regulating neuronal reprogramming of astrocytes. Cell Stem Cell 17: 74-88

Raposo AASF, Vasconcelos FF, Drechsel D, Marie C, Johnston C, Dolle D, Bithell A, Gillotin S, van den Berg DLC, Ettwiller L, Flicek O, Crawfrod GE, Parras CM, Berninger B, Buckley NJ, Guillemot F, Castro DS (2015) Ascl1 coordinately regulates gene expression and the chromatin landscape during neurogenesis. Cell Reports 10: 1544-1556

Bergami M, Masserdotti G, Temprana SG, Motori E, Eriksson T, Göbel J, Yang SM, Conzelmann K-K, Schinder AF, Götz M, Berninger B (2015) A critical period of experience-dependent remodelling of adult-born neuron connectivity. Neuron 85: 710-717

Heinrich C, Spagnoli FM, Berninger B (2015) In vivo reprogramming for tissue repair. Nature Cell Biology 17: 204-211

Karow M, Berninger B (2015) In-TOX-icating neurogenesis. The EMBO Journal 34: 832-4. embj.201591107

Publications 2014

Heinrich C, Bergami M, Gascón S, Lepier A, Viganò F, Dimou L, Sutor B, Berninger B, Götz M. (2014) Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral Cortex. Stem Cell Reports 3(6): 1000-14. doi: 10.1016/j.stemcr.2014.10.007.

García-González D, Murcia-Belmonte V, Esteban PF, Ortega F, Díaz D, Sánchez-Vera I, Lebrón-Galán R, Escobar-Castañondo L, Martínez-Millán L, Weruaga E, García-Verdugo JM, Berninger B, de Castro F (2014).  Anosmin-1 over-expression increases adult neurogenesis in the subventricular zone and neuroblast migration to the olfactory bulb. Brain Structure and Function 2014 Oct 10. [Epub ahead of print]

Karow M, Schichor C, Beckervordersandforth R, Berninger B. (2014) Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons. J Vis Exp. 2014 May 12;(87). doi: 10.3791/51433. PMID:24893711

Arlotta P, Berninger B. (2014) Brains in metamorphosis: reprogramming cell identity within the central nervous system. Curr Opin Neurobiol. 2014 May 3;27C:208-214. doi: 10.1016/j.conb.2014.04.007.

Publications 2013

Deshpande A., Bergami M., Ghanem A., Conzelmann K.-K., Lepier A., Goetz M., Berninger B. (2013) Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013; 110 (12): E1152-E1161

Motori E., Puyal J., Toni N., Ghanem A., Angeloni C., Malaguti M., Cantelli-Forti G., Berninger B., Conzelmann K.-K., Goetz M., Winklhofer K. F., Hrelia S., Bergami M. (2013) Inflammation-Induced Alteration of Astrocyte Mitochondrial Dynamics Requires Autophagy for Mitochondrial Network Maintenance
CELL METABOLISM. 2013; 18 (6): 844-859

Ortega F., Gascon S., Masserdotti G., Deshpande A., Simon C., Fischer J., Dimou L., Lie D. C., Schroeder T., Berninger B. (2013) Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling
NATURE CELL BIOLOGY. 2013; 15 (6): 602-+

Publications 2012

Karow M., Sanchez R., Schichor C., Masserdotti G., Ortega F., Heinrich C., Gascon S., Khan M. A., Lie D. C., Dellavalle A., Cossu G., Goldbrunner R., Goetz M., Berninger B.  (2013) Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells
CELL STEM CELL. 2012; 11 (4): 471-476

Further Information about the Research Group