Research group Cell biology and Neuroscience

GABAergic circuits regulate information flow in the brain and thereby shape behavior. Disruptions in GABAergic signaling occur in numerous psychiatric and neurological disorders. Although GABA(A)​ receptors are already targeted pharmacologically, many available drugs act broadly throughout the central nervous system and therefore cause relevant side effects.

Our research group investigates the molecular diversity of GABAergic synapses. These synapses differ depending on brain region and neuronal subtype, potentially enabling more selective therapeutic approaches. By combining molecular, functional, and behavioral studies in mouse models, we aim to identify circuit-specific targets. Our main focus is on GABAergic synapses in the amygdala, hippocampus, and prefrontal cortex and their roles in anxiety and social behavior.