In a multi-centre clinical cohort study, the influence of treatment guideline conformance for breast cancer patients on disease free status and overall survival is investigated. The question of therapy decisions during primary treatment is central: breast-conserving therapy, removal of the axillary lymph nodes, radiation therapy, adjuvant chemotherapy and hormone therapy.
In contrast to randomised therapy studies, all breast cancer patients are observed and followed up. The implications of taking part in a randomised study for disease progress will also be examined. The study consists of a retrospectively defined cohort of about 3500 breast cancer patients treated between 1992 and 2005 at the Women’s Hospital in Ulm, as well as patients treated in a local network of 14 breast centres in the years 2003 to 2005.
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Funding: German Federal Ministry for Education and Research (BMBF)