The Tenzer laboratory focuses on the development, optimization and application of methods for quantitative proteome analysis. (Please visit the ISOQuant project page for further information.) In this context, the Core Facility "Mass Spectrometry" of the Research Center for Immunotherapy (FZI) was established in 2005 and has since been continuously expanded and extended. Additionally, there are close interactions with the Focus Program Translational Neurosciences (FTN). Currently, two high-performance mass spectrometry platforms (Waters nanoUPLC + Synapt G2-Si) are available for quantitative proteome analyses, which are used within the scope of many cooperation projects, for example in the DFG program SPP1580 "Intracellular Compartments as Places of Pathogen - Host Interaction". Furthermore, the Tenzer laboratory investigates the characterization of proteases in MHC class I restricted antigen processing as well as the mass spectrometric identification of MHC presented peptides (HUPO-HIPP). Another focus of our research is the characterization of the interaction of nanoparticles with biological media within the framework of the DFG Collaborative Research Center SFB 1066.
Univ.-Prof. Dr. rer. nat. Stefan Tenzer
Phone: +49 (0)6131 17-6199