In order to detect paroxysmal atrial fibrillation after stroke and be able to make use of the effective secondary effect of oral anticoagulation, it is necessary to perform prolonged ECG-monitoring for at least 72 hours. However prolonged monitoring times are not yet routine in clinical practice. We developed and validated the AS5F score to help select patients for prolonged ECG-monitoring. The AS5F score calculates the probability of pAF-detection and the Number Needed to Screen within 72 hours of Holter-ECG, based on a patient’s age, NIH-SS at admission and TIA vs. ischemic stroke.