Modification of Dopamine D2-receptor Concentration in Patients with Epilepsy
We were able to see a 30% reduction of D2-Receptor bonds in the temporal lobe of patients with temporal lobe epilepsy. The effects of this change must be studied in various patient groups. Through the D2 Receptors, Dopamine could have a modulating effect on the excitability of the cerebral cortex and therefore could be, in terms of pathophysiology, significant.