2011

Bauer M., Goldstein M., Christmann M., Becker H., Heylmann D., Kaina B. (2011) Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress, Proceedings of the National Academy of Sciences of the USA, 108, 21105-21110



Christmann M., Verbeek B., Roos W.P., Kaina B. (2011) O⁶-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: enzyme activity, promoter methylation and immunohistochemistry, Biochem Biophys Acta, 1816, 179-190



Efferth T., Kaina B. (2011) Toxicities by herbal medicines with emphasis to traditional Chinese medicine, Current Drug Metabolism, 12, 989-996



Dietrich C. (2011) The AHR in the control of cell cycle and apoptosis, in the AH receptor in Biology and Toxicology, (ed R. Pohjanvirta), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118140574.ch32



Frank H., Funk M., Oesch F., Platt K.L. (2011) Synthesis, absolute configuration, and bacterial mutagenicity of the 8 stereoisomeric vicinal diol epoxides at the terminal benzo ring of carcinogenic dibenz[a,h]anthracene, Chemical Research in Toxicology, 24, 2258-2268



Berdelle N., Nikolova T., Quiros S., Efferth T., Kaina B. (2011) Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells, Molecular Cancer Therapeutics, 10, 2224-2233



Quiros S., Roos W.P., Kaina B. (2011) Rad51 and BRCA2 – New molecular targets for sensitizing glioma cells to alkylating anticancer drugs, PLoS ONE, DOI: 10.1371/journal.pone.0027183




Hamalukic M., Huelsenbeck J., Schad A., Wirtz S., Kaina B., Fritz G. (2011) Rac-1 regulated endothelial radiation response stimulates extravasation and metastasis that can be blocked by HMG-CoA reductase inhibitors, Plos One, 6:e26413



Reichert S., Rödel C., Mirsch J., Harter P.N., Tomicic M.T., Mittelbronn M., Kaina B., Rödel F. (2011) Survivin inhibition and DNA double-strand break repair: A molecular mechanism to overcome radioresistance in glioblastoma, Radiotherapy and Oncology, 101, 51-58



Olsen B.B., Fischer U., Rasmussen T.L., Montenarh M., Meese E., Fritz G., Issinger O.G. (2011) Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2 a' levels, Molecular and Cellular Biochemistry, 356, 139-147

Hülsenbeck J., Henninger C., Schad A., Lackner K.J., Kaina B., Fritz G. (2011) Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity, Cell Death Disease 2:e190

 

Cimbora-Zovko T., Brozovic A., Piantanida I., Fritz G., Virag A., Alic B., Majce V., Kocevar M., Polanc S., Osmak M. (2011) Synthesis and biological evaluation of 4-nitro-substituted 1,3-diaryltriazenes as a novel class of potent antitumor agents, European Journal of Medicinal Chemistry, 46, 2971-2983



Roos W.P., Jöst E., Belohlavek C., Nagel G., Fritz G., Kaina B. (2011) Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by interferon-ß and valproic acid, Cancer Research, 71, 4150-4160



Kaina B., Christmann M. (2011) DNA-Schadensantwort und ihre pharmakologische Beeinflussung / DNA damage response and its pharmacological inhibition, Der Onkologe, 17, 503-512



Tomicic M.T., Reischmann P., Rasenberger B., Meise R., Kaina B., Christmann M. (2011) Delayed c-Fos activation in human cells triggers XPF induction and an adaptive response to UVC-induced DNA damage and cytotoxicity, Cellular and Molecular Life Sciences, 68, 1785-1798



Nilsson S., Hülsenbeck J., Fritz G. (2011) Mevalonate pathway inhibitors affect anticancer drug-induced cell death and DNA damage response of human sarcoma cells, Cancer Letters, 304, 60-69



Helbig L., Damrot J., Hülsenbeck J., Köberle B., Brozovic A., Osmak M., Fiket Z., Kaina B., Fritz G. (2011) Late activation of stress-activated protein kinases/c-Jun N-terminal kinases triggered by cisplatin-induced DNA damage in repair-defective cells, Journal of Biological Chemistry, 286, 12991-13001



Küppers M., Faust D., Linz B., Dietrich C. (2011) Regulation of ERK1/2 activity upon contact inhibition in fibroblasts, Biochemical and Biophysical Research Communications, 406, 483-487



Wiese C., Nikolova T., Zahanich I., Sulzbacher S., Fuchs J., Yamanaka S., Graf E., Ravens U., Boheler K.R., Wobus A.M. (2011) Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin, International Journal of Cardiology, 147, 95-111



Fritz G., Henninger C., Hülsenbeck J. (2011) Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents, British Medical Bulletin, 97, 17-26




Sciuscio D., Diserens A.C., van Dommelen K., Martinet D., Jones G., Janzer R.C., Pollo C., Hamou M.F., Kaina B., Stupp R., Levivier M., Hegi M.E. (2011) Extent and patterns of MGMT promoter methylation in glioblastoma and respective derived spheres, Clinical Cancer Research, 17, 255-266




Dietrich C. (2011) Dioxin, persistentes risiko: wirkungen und mechanismen von dioxin, Labor&More, 1.11, 33-35

Christmann M., Kaina B. (2011) O6-Methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy, (Buchbeitrag).