2017

Kaowinn S., Won Jun S., Seok Kim C., Shin D.-M., Hwang Y.-H., Kim K., Shin B., Kaewpiboon C., Hee Jeong H., Seok Koh S., Krämer O.H., Johnston R.N., Chung Y.-H. (2017) Increased EGFR Expression induced by a novel oncogene, CUG2, confers resistance to doxorubicin through Stat1-HDAC4 signaling  Cell Oncol. (Pdf, 9,0 MB) s13402-017-0343-7



Mahendrarajah N., Borisova M.E., Reichardt S., Godman M., Sellmer A., Mahboobi S., Haitel A., Schmid K. Kenner L., Heinzel T., Beli P., Krämer O.H. (2017)  HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3 Cellular Signalling   (Pdf, 1,0 MB)39 9-17 

    

Tomaszowski K.-H., Hellmann N., Takatsu H., Shin H.-W., Kaina B. (2017) Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases Scientific Reports (Pdf, 1,5 MB) in press



Christmann M., Kaina B. (2017) Epigenetic regulation of DNA repair genes an implications for Tumor therapy Mutation Research-Reviews in Mutation Reseach (Pdf, 1,1 MB) in press



Wenz C., Faust D., Linz B., Turmann C., Nikolova T., Bertin J., Gough P., Wipf P., Schröder A.S., Krautwald S., Dietrich C. (2017) t-BuOOH induces ferroptosis in human and murine cell lines Arch Toxicol  (Pdf, 1,7 MB) in press



Kaina B. (2017) DNA und Darmkrebs: Wie Escheria coli und Darmzellen sich vor Genotoxinen schützen Naturwissenschaftliche Rundschau  (Pdf, 1,3 MB)7 328-335



Seiwert N., Neitzel C., Stroh S., Frisan T., Audebert M., Toulany M., Kaina B., Fahrer J (2017) AKT2 suppresses pro survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells Cell Death and Disease  (Pdf, 3,4 MB)8,e3019



Nikolova T., Kiweler N., Krämer O.H. (017) Interstrand Crosslink Repair as a Target for HDAC Inhibition Review Trends in Pharmacological Sciences in Press



Nikolova T., Marini ., Kaina B. (2017) Genotoxicity testing: Comparison of the γH2AX focus assay with te alkaline and neutral comet assays Mutation Research - Genetic Toxikology and Environmental Mutagenesis Elsevier (Pdf, 850,5 KB) 1383-5718



Fahrer J., Kaina B. (2017)  Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carciogens Food and Chemical Toxicology Elsevier  (Pdf, 1,7 MB)0278-6915



Kitsera N., Allgayer J., Parsa E., Geier N., Rossa M., Carell T., Khobta A. (2017) Functional Impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter Nucleic Acids Research 1-13, in press



Mertsch S., Krämer OH. (2017) The interplay between histone deacetylase and rho kinases is important for cancer and neurodegeneration, Elsevier (Pdf, 2,6 MB)



Stojanovic N., Hassan Z., Wirth M., Wenzel P., Beyer M., Schäfer C., Brand P., Kroemer A., Stauber RH., Schmid RM., Arlt A., Sellmer A., Mahboobi S., Rad R., Reichert M., Saur D., Krämer OH., Schneider G.(2017) HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer, Oncogene (Pdf, 2,6 MB), 36:1804-1815



Schäfer C., Göder A., Beyer M., Kiweler N., Mahendrarajah N., Rauch A.,  Nikolova T., Stojanovic N., Wieczorek M., Reich TR., Tomicic MT., Linnebacher M., Sonnemann J., Dietrich S., Sellmer A., Mahboobi S., Heinzel T., Schneider G., Krämer OH. 2017 Class I histone deacetylases regulate p53/NF-kappaB crosstalk in cancer cells, Elsevier (Pdf, 1,3 MB), 29:218-225



Freund P., Kerenyi MA., Hager M., Wagner T., Wingelhofer B., Pham HTT., Elabd M., Han X., Valent P., Gouilleux F., Sexl V., Krämer OH., Groner B., Moriggl R., O-GlcN Acylation of STA5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies, Leukemia (Pdf, 3,3 MB), 1-11



Noack K., Mahendrarajah N., Hennig D., Schmidt L., Grebien F., Hildebrand D., Christmann M., Kaina B., Sellmer A., Mahboobi S., Kubatzky K., Heinzel T., Krämer OH. (2017) Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells, Arch Toxicol (Pdf, 1,3 MB), 91: 2191-2208



Wetzel F., Mittag S., Cano-Cortina M., Wagner T., Krämer O.H., Niedenthal R., Gonzales-Mariscal L., Huber O. (2017) SUMOylation regulates the intracellular fate of ZO-2, Cellular an Molecular Life Sciences (Pdf, 4,1 MB) , 74:373-392  



Ponath V., Kaina B. (2017) Death of monocytes through oxidative burst of macrophages and neutrophils: killing in trans, PLoS ONE (Pdf, 3,4 MB), 12(1):e0170347,  1-20


Schäfer C., Göder A., Beyer M., Kiweler N., Mahendrarajah M., Rauch A., Nikolova T., Stojanovic N., Wieczorek M., Reich T., Tomicic M., Linnebacher M., Sonnem,ann J., Dietrich S., Sellmer A., Mahboobi S., Heinzel T., Schneider G., Krämer O.H. (2017) Class I histone deacetylases regulate p53/NF-kB crosstalk in cancer cells, Cellular Signalling   (Pdf, 1,3 MB)29, 218-225
 

Krumm A., Roos W. (2017) Assessing the effect of class I histone deacethylase activity on DNA double-strand break repair by homologous recombination, chapter 9, in Oliver H. Krämer (ed.),  HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols (Pdf, 13,6 MB), Methods in Molecular biology, Springer Science Media, New York, 115-123



Nikolova T., Göder A., Parplys A., Borgmann K. (2017) DNA fiber spreading assay to test HDACi effects on DNA and its replication, chapter 8, in Oliver H. Krämer (ed.), HDAC /HAT Function Assessment and Inhibitor Development: Methods and Protocols, Methods in Molecular Biology, Springer Science Media, New York, 103-113



Reich Thomas R., Switzeny Olivier J., Renovanz M., Sommer C., Kaina B., Christmann M., Tomicic Maja T. (2017) Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome, Oncotarget (Pdf, 2,0 MB), 1-14



Fahrer J., Kaina B. (2017) Chemische Kanzerogenese, Helmut Greim: Das Toxikologiebuch (1), Wiley-VCH Verlag, 151



Bergholz L. M., Subic-Wrana C., Heylmann D., Beutel M. E., Wiltink J., Kaina B. (2017) DNA damage in lymphocytes of patients suffering from complex traumatization, DNA Repair, in press



Nikolova T., Roos W.P., Krämer O.H., Strik H.M., Kaina B. (2017) Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling, Biochimica et Biophysica Acta, Elsevier, 29-39

Christmann M., Diesler K., Majhen D., Steigerwald C., Berte N., Freund H., Stojanovic N., Kaina B., Osmak M., Ambriovic-Ristov A., Tomicic M.T. (2016) Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair, Oncotarget (Pdf, 10,0 MB), 8:27754-27771

 

Faust D., Nikolova T., Wätjen W., Kaina B., Dietrich C. (2017) The Brassica-derived phytochemical indolo [3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation,  Arch. Toxicol   (Pdf, 941,0 KB)91: 967-982