Visual Universitätsmedizin Mainz



Runkel S, Hitzler WE, Hellstern P. The impact of whole blood processing and freezing conditions on the quality of therapeutic plasma prepared from whole blood. Transfusion. 2015; 55(4):796-804


Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC and Provost P. Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function. Platelets, 2014.

Teschner D, Distler E, Wehler D, Frey M, Marandiuc D, Langeveld K, Theobald M, Thomas S and Herr W. Depletion of naive T cells using clinical grade magnetic CD45RA beads: a new approach for GVHD prophylaxis. Bone Marrow Transplant, 2014. 49(1): p. 138-44.


Hitzler WE. Single-donor (apheresis-)platelets and pooled whole-blood-derived platelets - Signifcance and assessment of both products. Clin Lab, 2014(4): p. 1-39.

Vamvakas EC and Hitzler WE. Consistency and proportionality in policy decision-making in blood safety: the case for an all-apheresis platelet supply in Germany. Clin Lab, 2013. 59(1-2): p. 1-22.

Vamvakas EC and Hitzler WE. Donor exposures in recipients of pooled platelet concentrates: a case-study in arithmetic, logic, "expert opinion", and the "peer review" process. Clin Lab, 2013. 59(3-4): p. 415-20.

Vamvakas EC and Hitzler WE. Interventions to reduce platelet prophylactic transfusions in patients with hypoproliferative thrombocytopenia: providing patients with the full benefit. Clin Lab, 2013. 59(5-6): p. 459-64.

Vamvakas EC, Hitzler W. Consistenca and porportionality in policy decision-making in blood safety: th case for an all-apheresis platelet supply in Germany. Clin Lab, 2013;59:1-22

Maccagno G, Heise M, Hoppe-Lotichius M, Weyer V, Conradi R and Hitzler W. Ischemic-type biliary lesions after liver transplantation: a retrospective analysis of risk factors and outcome. Clin Lab, 2013. 59(7-8): p. 747-55.

Best CT, F.; Hitzler, W.E.; Dieterich, M. Plasmapheresis as effective treatment in chronic Cogan-I-Syndrome. Immunol Lett, 2013(150): p. 87-8.

Best C, Thomke F, Hitzler W and Dieterich M. Plasmapheresis as effective treatment in chronic active Cogan-I-syndrome. Immunol Lett, 2013. 150(1-2): p. 87-8.

Arnold ML, Heinemann FM, Horn P, Ziemann M, Lachmann N, Muhlbacher A, Dick A, Ender A, Thammanichanond D, Fischer GF, Schaub S, Hallensleben M, Mytilineos J, Hitzler WE, Seidl C, Doxiadis, II and Spriewald BM. 16(th) IHIW: anti-HLA alloantibodies of the of IgA isotype in re-transplant candidates. Int J Immunogenet, 2013. 40(1): p. 17-20.


Weibrich G, Kleis WK, Streckbein P, Moergel M, Hitzler WE and Hafner G. Comparison of point-of-care methods for preparation of platelet concentrate (platelet-rich plasma). Int J Oral Maxillofac Implants, 2012. 27(4): p. 762-9.

John ML, Hitzler W and Scharrer I. The role of human leukocyte antigens as predisposing and/or protective factors in patients with idiopathic thrombotic thrombocytopenic purpura. Ann Hematol, 2012. 91(4): p. 507-10.

Hocher B, Gron HJ, Schumann C, Tsuprykov O, Seifert S, Hitzler WE and Armbruster FP. Vitamin D status from dried capillary blood samples. Clin Lab, 2012. 58(7-8): p. 851-5.


Hitzler W and Vamvakas EC. Platelet microRNA profiles and the effect of pathogen reduction on platelet function. Clin Lab, 2011. 57(7-8): p. 451-4.


Heuft HG and Hitzler W. The Pathogenetic Background of Transfusion-Associated Acute Lung Injury Cannot Be Confined to the Passive Transfer of Donor Leucocyte Antibodies to Transfusion Recipients. Transfus Med Hemother, 2008. 35(2): p. 70-72.

Gurtler L, Blumel J, Burger R, Drosten C, Groner A, Heiden M, Hitzler W, Jansen B, Klamm H, Ludwig WD, Montag-Lessing T, Offergeld R, Pauli G, Seitz R, Schlenkrich U, Schottstedt V and Willkommen H. Arbobacteria - Pathogens Transmittable by Arthropods. Transfus Med Hemother, 2008. 35(5): p. 374-390.


Weichold FF, Mueller S, Kortsik C, Hitzler WE, Wulf MJ, Hone DM, Sadoff JC and Maeurer MJ. Impact of MHC class I alleles on the M. tuberculosis antigen-specific CD8+ T-cell response in patients with pulmonary tuberculosis. Genes Immun, 2007. 8(4): p. 334-43.

Seitz R, von Auer F, Blumel J, Burger R, Buschmann A, Dietz K, Heiden M, Hitzler WE, Klamm H, Kreil T, Kretzschmar H, Nubling M, Offergeld R, Pauli G, Schottstedt V, Volkers P and Zerr I. Impact of vCJD on blood supply. Biologicals, 2007. 35(2): p. 79-97.

Hohn H, Kortsik C, Zehbe I, Hitzler WE, Kayser K, Freitag K, Neukirch C, Andersen P, Doherty TM and Maeurer M. MHC class II tetramer guided detection of Mycobacterium tuberculosis-specific CD4+ T cells in peripheral blood from patients with pulmonary tuberculosis. Scand J Immunol, 2007. 65(5): p. 467-78.


Zimmermann T, Maccagno G, Galle PR, Otto G, Hitzler WE and Schuchmann M. Alloimmune hemolytic anemia after liver transplantation from an ABO-identical and Rh-nonidentical donor in a patient with postpartum Budd-Chiari syndrome. Transpl Int, 2006. 19(6): p. 514-5.

Schlitt A, Hamilton K, Maegdefessel L, Dahm M, Theis C, Eichler M, Brockmann O, Steinseifer U, Hauroeder B, Hitzler WE and Rupprecht HJ. Comparison of fondaparinux, low molecular-weight heparin and unfractionated heparin in preventing thrombus formation on mechanical heart valves: results of an in-vitro study. J Heart Valve Dis, 2006. 15(6): p. 809-14.


Weibrich G, Kleis WK, Hitzler WE and Hafner G. Comparison of the platelet concentrate collection system with the plasma-rich-in-growth-factors kit to produce platelet-rich plasma: a technical report. Int J Oral Maxillofac Implants, 2005. 20(1): p. 118-23.

Tully G, Kortsik C, Hohn H, Zehbe I, Hitzler WE, Neukirch C, Freitag K, Kayser K and Maeurer MJ. Highly focused T cell responses in latent human pulmonary Mycobacterium tuberculosis infection. J Immunol, 2005. 174(4): p. 2174-84.

Runkel S, Haubelt H, Hitzler W and Hellstern P. The quality of plasma collected by automated apheresis and of recovered plasma from leukodepleted whole blood. Transfusion, 2005. 45(3): p. 427-32.

Runkel S, Bach J, Haubelt H, Anders C, Hitzler W and Hellstern P. The impact of two whole blood inline filters on markers of coagulation, complement and cell activation. Vox Sang, 2005. 88(1): p. 17-21.

Oerke S, Hohn H, Zehbe I, Pilch H, Schicketanz KH, Hitzler WE, Neukirch C, Freitag K and Maeurer MJ. Naturally processed and HLA-B8-presented HPV16 E7 epitope recognized by T cells from patients with cervical cancer. Int J Cancer, 2005. 114(5): p. 766-78.

Jecker P, Melzer A and Hitzler WE. [Necessity for blood transfusion in head and neck surgery]. HNO, 2005. 53(11): p. 945-51.

Hess G, Runkel S, Zdunek D and Hitzler WE. N-terminal pro-brain natriuretic peptide (NT-proBNP) in healthy blood donors and in patients from general practitioners with and without a diagnosis of cardiac disease. Clin Lab, 2005. 51(3-4): p. 167-72.

Hess G, Runkel S, Zdunek D and Hitzler WE. Reference interval determination for N-terminal-B-type natriuretic peptide (NT-proBNP): a study in blood donors. Clin Chim Acta, 2005. 360(1-2): p. 187-93.


Hitzler WE and Runkel S. Prevalence, persistence and liver enzyme levels of HGV RNA-positive blood donors determined by large-scale screening and transmission by blood components. Clin Lab, 2004. 50(1-2): p. 25-31.

Weibrich G, Hansen T, Kleis W, Buch R and Hitzler WE. Effect of platelet concentration in platelet-rich plasma on peri-implant bone regeneration. Bone, 2004. 34(4): p. 665-71.


Weibrich G, Kleis WK, Hafner G, Hitzler WE and Wagner W. Comparison of platelet, leukocyte, and growth factor levels in point-of-care platelet-enriched plasma, prepared using a modified Curasan kit, with preparations received from a local blood bank. Clin Oral Implants Res, 2003. 14(3): p. 357-62.

Weibrich G, Kleis WK, Buch R, Hitzler WE and Hafner G. The Harvest Smart PRePTM system versus the Friadent-Schutze platelet-rich plasma kit. Clin Oral Implants Res, 2003. 14(2): p. 233-9.


Weibrich G, Buch RS, Kleis WK, Hafner G, Hitzler WE and Wagner W. Quantification of thrombocyte growth factors in platelet concentrates produced by discontinuous cell separation. Growth Factors, 2002. 20(2): p. 93-7.

Weibrich G, Kleis WK, Hafner G and Hitzler WE. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J Craniomaxillofac Surg, 2002. 30(2): p. 97-102.

Hohn H, Neukirch C, Freitag K, Necker A, Hitzler W, Seliger B and Maeurer MJ. Longitudinal analysis of the T-cell receptor (TCR)-VA and -VB repertoire in CD8+ T cells from individuals immunized with recombinant hepatitis B surface antigen. Clin Exp Immunol, 2002. 129(2): p. 309-17.Clin Lab, 2000. 46(5-6): p. 291-3.

Hitzler WE and Runkel S. Prevalence of human parvovirus B19 in blood donors as determined by a haemagglutination assay and verified by the polymerase chain reaction. Vox Sang, 2002. 82(1): p. 18-23.


Hitzler WE, Wolf S, Runkel S and Kunz-Kostomanolakis M. Comparison of intermittent- and continuous-flow cell separators for the collection of autologous peripheral blood progenitor cells in patients with hematologic malignancies. Transfusion, 2001. 41(12): p. 1562-6.

Hitzler WE and Runkel S. Routine HCV PCR screening of blood donations to identify early HCV infection in blood donors lacking antibodies to HCV. Transfusion, 2001. 41(3): p. 333-7.

Hitzler WE and Runkel S. Screening of blood donations by hepatitis C virus polymerase chain reaction (HCV-PCR) improves safety of blood products by window period reduction. Clin Lab, 2001. 47(5-6): p. 219-22.

Hellstern P, Bach J, Haubelt H, Hitzler WE, Mathis S and Vogt A. The impact of the intensity of serial automated plasmapheresis and the speed of deep-freezing on the quality of plasma. Transfusion, 2001. 41(12): p. 1601-5.

Ecker T and Hitzler WE. Effect of 6-hour exposure to 20 degrees C on the ATP content and other biochemical measures of CPDA-1 packed red cells. Clin Lab, 2000. 46(5-6): p. 291-93.