International Medical Services
NeuroKine Projects
The members of the NeuroKine consortium use different models and cover different aspects of research and methods. In this way, they can provide a unique opportunity for both research and education of immunological diseases of the central nervous system (CNS). These are the projects they are working on:
The profile of infiltrating T cells in the CNS
Further information (Pdf 
, 271,0 KB)
Supervisor: Ari Waisman
Researcher: Alma Mohebiany
Partner: University Medical Center Mainz, Germany
Generation of novel mouse lines to elucidate the role of interleukin-23 in inflammatory disease of the CNS
Further information (Pdf , 256,9 KB)
Supervisor: Ari Waisman
Researcher: Maja Kitic
Partner: University Medical Center Mainz, Germany
Identification of IL-23 responsive cell populations and their impact on inflammation using IL-23R- conditional mice
Further information (Pdf , 241,2 KB)
Supervisor: Burkhard Becher
Researcher: Tom Hartwig
Partner: University of Zurich, Switzerland
IL-23 in autoimmune neuroinflammation
Further information (Pdf , 204,0 KB)
Supervisor: Burkhard Becher
Researcher: Melania Balzarolo
Partner: University of Zurich, Switzerland
Nature of the inflammatory response in Multiple Sclerosis lesions
Further information (Pdf , 202,4 KB)
Supervisor: Hans Lassmann
Researcher: Joana Machado Dos Santos
Partner: University of Vienna, Austria
Analysing the immune targeting of neurons by autoreactive T cells in autoimmune diseases of the central nervous system
Further information (Pdf , 221,4 KB)
Supervisor: Roland Liblau
Researcher: Christina Gebauer
Partner: INSERM Toulouse, France
Effect of multiple antigens cross-reacting TCRs on pathogenesis of central nervous system autoimmunity
Further information coming soon
Supervisor: Roland Liblau
Researcher: Manish Malviya
Partner: INSERM Toulouse, France
Impact of inflammation on neural stem cells and tissue repair
Further information (Pdf , 235,6 KB)
Supervisor: Gianvito Martino
Researcher: Hélène Descamps
Partner: San Raffaele Hospital Milan, Italy
Cytokines driving innate and adaptive immunity in the non-human primate marmoset EAE model for MS
Further information (Pdf , 209,8 KB)
Supervisor: Jon Laman and Bert ‘t Hart
Researcher: Jordon Dunham
Partner: University Medical Center Groningen, The Netherlands
Cellular targets and downstream effector mechanisms of IL-12/IL-23 signalling in Alzheimer´s disease
Further information (Pdf , 220,7 KB)
Supervisor: Frank Heppner
Researcher: Pascale Eede
Partner: Charité - University Berlin, Germany
Function and role of astrocytes in CNS inflammation
Further information (Pdf , 213,0 KB)
Supervisor: Melanie Jungblut
Researcher: Hui Zhang
Partner: Miltenyi Biotec GmbH, Bergisch-Gladbach, Germany
Antigen-specific immunotherapy
Further information (Pdf , 185,5 KB)
Supervisor: David Wraith
Researcher: Anja Wegner
Partner: Apitope Technology Ltd, Bristol, United Kingdom
Project title tbc
Further information coming soon
Supervisor: Thomas Hoffmann
Researcher: Elisa Colombo
Partner: Phenex Pharmaceuticals AG, Mainz, Germany
Development of a novel single-cell T cell receptor profiling platform using next-generation sequencing (NGS)
Further information (Pdf , 289,3 KB)
Supervisor: Tana Omokoko
Researcher: Shaheer El-Bardisy
Partner: BioNTech AG, Mainz, Germany
Understanding the regulatory mechanism at the choroid plexus in a transgenic model of Alzheimer's disease
Further information (Pdf , 243,2 KB)
Supervisor: Michal Schwartz
Researcher: Alaa Sharif
Partner: Weizmann Institute of Science, Rehovot, Israel