Visual Universitätsmedizin Mainz

2018

 

Heylmann D., Badura J., Becker H., Fahrer J., Kaina B. (2018)Sensitivity of CD3/CD28-stimulated versus non-stimulated lymphocytes to ionizing Radiation and genotoxic anticancer drugs: key role of ATM in the differential radiation response, Cell Death & Disease, 9 (11): 1053

 

Rund K.M., Ostermann A.I., Kutzner L., Galano J.M., Oger C., Vigor C., Wecklein S., Seiwert N., Durand T., Schebb N.H. (2018) Development of an LC-ESI(-)-MS/MS method for the simultaneous quantification of 35 isoprostanes and isofurans, Analytica Chimica Acta, 1037: 63-74

 

Dörsam B., Seiwert N., Försch S., Stroh S., Nagel G., Begaliew D., Diehl E., Kraus A., Mc Keague M., Minneker V., Roukos V., Reißig S., Waisman A., Moehler M., Stier A., Mangerich M., Dantzer F., Kaina B; Fahrer J. (2018) PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression, Proc Natl Acad Sci USA, 115(17): E4061-E4070

 

Tomicic M., Christmann M. (2018) Targeting anticancer drug-induced senescence in glioblastoma therapy, Oncotarget, vol. 9, (No. 101), 37466 - 37467

 

Ponath V., Heylmann D., Haak T., Woods K., Becker H., Kaina B. (2018) Compromised DNA Repair and Signalling in Human Granulocytes, Journal of Innate Immunity, DOI: 10.1159/000492678, 1-12

 

Gock M., Mullins C.S., Harnack C., Prall F., Ramer R., Göder A., Krämer O.H., Klar E., Linnebacher M. (2018) Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line, World Journal of Gastroenterology, 24(33): 3749-3759.

 

Stojanovic N., Dekanic A., Paradzik M., Majhen D., Ferencak K., Ruscic J., Bardak I., Supina C., Tomicic Maja T., Christmann M., Osmak M., Ambriovic-Ristov A. (2018) Differential effects of integrin αv knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons, Molecular Pharmacology, DOi: 10.1124/mol.118.113027.

 

Kaowinn S., Kaewpiboon C., Koh S.S., Krämer O.H., Chung Y.-H. (2018) STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2, Oncology Reports, 40: 2619-2627.

 

Kaina B., Izzoti A., Xu J., Christmann M., Pulliero A., Zhao X., Dobreanu M., Au W.W. (2018) Inherent and toxicant-provoked reduction in DNA repair capacity: A key mechanism for personalized risk assessment, cancer prevention and intervention, and response to therapy, International Journal of Hygiene and Environmental Health, vol.221, issue 7, ,993-1006.

 

Tomicic M.T. (2018) Replica to the Opinion Letter regarding the article Sensitization of colorectal cancer cells to irinotecan by the Survivin Inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53, https://doi.org/10.1007/s00204-018-2288-7, Archives of Toxicology.

 

Rauch A., Carlstedt A., Emmerich C., Mustafa Al-H., Göder A., Knauer S., Linnebacher M., Heinzel T., Krämer O.H. (2018) Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells Oncotarget, Vol.9 (No.45), 27835-27850

 

Kiweler N., Brill B., Wirth M., Breuksch I., Laguna T., Dietrich C., Strand S., Schneider G., Groner B., Butter F., Heinzel T., Brenner W., Krämer O.H., (2018) The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells Archives of Toxicology, 92:2227-2243

 

Steigerwald C., Rasenberger B., Christmann C., Tomicic Maja T., (2018) Sensitization of colorectal cancer cells to irinotecan by the Survivin inhibitor LLP3 depends on XAF1 proficiency in the context of mutated p53 Archives of Toxicology DOI 10.1007/s00204-018-2240-x, 92:2645-2648

 

Krüger K., Geist K., Stuhldreier F., Schumacher L., Blümel L., Remke M., Wesselborg S., Stork B., Klöcker N., Bormann S., Roos W., Honnen S., Fritz G., (2018) Multiple DNA damage-dependent and DNA damage-independent stress Responses define the outcome of ATR/Chk1 targeting in medulloblastoma cells Cancer letters (Pdf , 3,1 MB)430, 34-46

 

Roos W., Frohnapfel L., Quiros S., Ringel F., Kaina B., (2018) XRCC3 contributes to temozolomide resistance of glioblastoma cells by promoting DNA double-strand break repair Cancer letters (Pdf , 1,7 MB)424, 119-126

 

Sellmer A., Stangl H., Beyer M., Grünstein E., Leonhardt M., Pongraz H., Eichhorn E., Elz S., Striegl B., Jenei-Lanzl Z., Dove S., Straub R., Krämer O., Mahboobi S (2018) Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors Journal of Medicinal Chemistry (Pdf , 10,8 MB) 61 - 3454 - 3477

 

Pons M., Reichardt C., Hennig D., Nathan A., Kiweler N., Stocking C., Wichmann C., Christmann M., Butter F., Reichardt S., Schneider G., Heinzel T., Englert C., Hartkamp J., Krämer O., Mahendrarajah N. (2018) Loss of Wilms tumor 1 Ppotein is a marker for apoptosis in response to replicative stress in leukemic cells Archives of Toxicology  (Pdf , 4,9 MB)doi 10.1007/s00204-018-2202-3

 

Göder A., Emmerich C., Nikolova T., Kiweler N., Schreiber M., Kühl T., Imhof D., Christmann M., Heinzel T., Schneider G., Krämer O. (2018) HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130 Nature communications (Pdf , 2,9 MB)9:764

 

Zaini M., Müller C., de Jong T., Ackermann T., Hartleben G., Kortmann G., Gührs K., Fusetti F., Krämer O., Guryev V., Calkhoven C. (2018) A p300 and SIRT1 Regulated Acetylation Switch ofC/EBPalpha Controls Mitochondrial Function Cell Reports (Pdf , 2,9 MB) 22, 497-511

 

Kiweler N., Krämer O. (2018) PNUTS at the crossroads of tumorigenesis and metastasis formation Journal of Thoracic Disease (Pdf , 396,9 KB) 10 (2): 560 - 563

 

Hassan Z., Schneeweis C., Wirth M., Veltkamp C., Dantes Z., Feuerecker B., Ceyhan G., Knauer S., Weichert W., Schmid R., Stauber R., Arlt A.m, Krämer O., Rad R., Reichert M., Saaur D., Schneider G. (2018) MTOR Inhibitor-based combination therapies for pancreatic cancer British Journal of Cancer (Pdf , 1,8 MB) 118, 366-377

 

 

 

Wenz C., Faust D., Linz B., Turmann C., Nikolova T., Bertin J., Gough P., Wipf P., Schröder A., Krautwald S., Dietrich C. (2018) t-BuOOH induces ferrotopsis in human and murine cell lines Arch. Toxicol (Pdf , 1,7 MB)DOI 10.1007/s00204-017-2066-y, 92(2): 759-775

 

Aasland D., Reich T. R., Tomicic M. T., Switzeny O.J., Kaina B., Christmann M. (2018) Repair gene O6-methylguanine-DNA methyltransferase is controlled by SP1 and up-regulated by glucocorticoids, but not by temozolomide and radiation Journal of Neurochemistry (Pdf , 1,3 MB) 144: 139 - 151

 

 

 

 

 

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Institut für Toxikologie
Universitätsmedizin Mainz
Gebäude 905/4. OG
Obere Zahlbacher Str. 67
D-55131 Mainz
Germany

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