Publikationen 2024

Hieber C., Mustafa A.M., Neuroth S., Henninger S., Wollscheid H.P., Zabkiewicz J., Lazenby M., Alvares C., Mahboobi S., Butter F., Brenner W., Bros M., Krämer O.H. (2024) Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells, Biomed Pharmacother, 177:117076

Nguyen A., Mustafa A.M., Leydecker A.K., Halilovic M., Murr J., Butter F., Krämer O.H. (2024) The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells, Cell Commun Signal, 22(1):217

Kansy A.G., Ashry R., Mustafa A.M., Alfayomy A.M., Radsak M.P., Zeyn Y., Bros M., Sippl W., Krämer O.H. (2024) Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells, Mol Oncol. Pub ahead of print

Alfayomy A.M., Asry R., Kansy A.G., Sarnow A.C., Erdmann F., Schmidt M., Krämer O.H., Sippl W. (2024) Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase, European Journal of Medicinal Chemistry, volume 267, 116167

Kuhlen M., Hofmann T.G., Golas M.M. (2024), Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer, March 18, 2024, Trends in Cancer,

Beltzig L., Christmann M., Dobreanu M., Kaina B. (2024) Genotoxic and cytotoxic activity of Fisetin on Glioblastoma cells, Anticancer Research 44, doi: 10.21873/anticancers.11xxx

Strik H., Efferth T., Kaina B. (2024) Artesunate in glioblastoma therapy: Case reports and review of clinical studies, Phytomedicine, 123, 155274

Faust D., Wenz C., Holm S., Harms G., Greffrath W., Dietrich C. (2024) Cell-cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium, Archives of Toxicology,

Schmidt A., Allmann S., Schwarzenbach C., Snyder P., Chen J-X.,Nagel G.,Schöneis A., Beli P., Loewer A., Hofmann T.G., Tomicic M.T., Christmann M. (2024) The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence, Nucleic Acids Research, 1-19,

Keggenhoff F.L., Castven D., Becker D., Stojkovic S., Castven J., Zimpel C., Straub B.K., Gerber T., Langer H., Hähnel P., Kindler T., Fahrer J., O'Rourke C., Ehmer U., Saborowski A., Ma L., Wang X.W., Gaiser T., Matter M.S., Sina C., Derer S., Lee J.-S., Roessler S., Kaina B., Andersen J.B., Galle P.R., Marquardt J.U. (2024) PARP-1 selectively impairs KRAS-driven phenotypic and molecular features in intrahepatic cholangiocarcinoma, Gut, , 0:1-13, doi: 10.1136/gutjnl-2023-331237