Visual Universitätsmedizin Mainz


  • Meyer CU, Klopp J, Knoll R, Gehring S Beeinflussung des Mikrobioms durch Probiotika in der pädiatrischen Praxis. Monatsschr Kinderheilkd 2019 . 167:389-395
  • Härtel C, Pagel J, Spiegler J, Buma J, Henneke P, Zemlin M, Viemann D, Gille C, Gehring S, Frommhold D, Rupp J, Herting E, Göpel W. Lactobacillus acidophilus/Bifidobacteriuminfantis probiotics are associated with increasedgrowth of VLBWI among those exposed to antibiotics. Sci Rep. 2017 Jul17;7(1):5633. doi: 10.1038/s41598-017-06161-8.
  • Gehring S, Pietrzak-Nguyen A, Fichter M, Landfester K. Novel strategies in vaccine design: can nanocapsules help prevent and treat hepatitis B? Nanomedicine(Lond). 2017 Jun;12(11):1205-1207. doi: 10.2217/nnm-2016-0064. Epub 2017 May 18.
  • Llano López LH, Reischl AT, Gröndahl B, Kidszun A, Kowalzik F, Oetzmann von Sochaczewski C, Gehring S. The BioFireFilmArray enables point of care diagnostic in neonatal parechovirus meningitis. Infect Dis (Lond). 2017 Apr 11:1-3. doi:10.1080/23744235.2017.1311417.
  • Knoll RL, Forslund K, Kultima JR, Meyer CU, Kullmer U, Sunagawa S, Bork P, Gehring S. Gut microbiota differs between children with Inflammatory Bowel Disease and healthy siblings in taxonomic and functional composition: a metagenomic analysis. Am J Physiol Gastrointest Liver Physiol. 2017 Apr 1;312(4):G327-G339. doi: 10.1152/ajpgi.00293.2016.
  • Fichter M, Piradashvili K, Pietrzak-Nguyen A, Pretsch L, Kuhn G, Strand S, Knuf M, Zepp F, Wurm FR, Mailänder V, Landfester K, Gehring S. Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses. Biomaterials. 2016 Nov;108:1-12. doi:10.1016/j.biomaterials.2016.08.046. Epub 2016 Aug 31.
  • Pietrzak-Nguyen A, Piradashvili K, Fichter M, Pretsch L, Zepp F, Wurm FR, Landfester K, Gehring S. MPLA-coated hepatitis B virus surface antigen (HBsAg) nanocapsules induce vigorous T cell responses in cord blood derived human T cells. Nanomedicine. 2016 Nov;12(8):2383-2394. doi: 10.1016/j.nano.2016.07.010.
  • Welk A, Schmeh I, Knuf M, Groendahl B, Goebel J, Staatz G, Gawehn J, Gehring S. Acute Encephalopathy in Children Associated with Influenza A: A Retrospective Case Series. Klin Padiatr. 2016 Sep;228(5):280-1. doi: 10.1055/s-0042-111686.
  • Baier G, Fichter M, Kreyes A, Klein K, Mailänder V, Gehring S, Landfester K. Glutathione Responsive Hyaluronic Acid Nanocapsules Obtained by Bioorthogonal Interfacial "Click" Reaction. Biomacromolecules. 2016 Jan 11;17(1):148-53. doi: 10.1021/acs.biomac.5b01279. Epub 2015 Dec 16.
  • Baier, G.; Fichter, M.; Kreyes, A.; Klein, K.; Mailander, V.; Gehring, S.; Landfester, K. (2016): Glutathione Responsive Hyaluronic Acid Nanocapsules Obtained by Bioorthogonal Interfacial "Click" Reaction. In: Biomacromolecules 17 (1), S. 148–153. DOI: 10.1021/acs.biomac.5b01279.
  • Baier, G.; Winzen, S.; Messerschmidt, C.; Frank, D.; Fichter, M.; Gehring, S. et al. (2015): Heparin-based nanocapsules as potential drug delivery systems. In: Macromolecular bioscience 15 (6), S. 765–776. DOI: 10.1002/mabi.201500035.
  • Birkholz, J.; Doganci, A.; Darstein, C.; Gehring, S.; Zepp, F.; Meyer, C. U. (2014): IL-27 improves migrational and antiviral potential of CB dendritic cells. In: Hum Immunol 75 (6), S. 584–591. DOI: 10.1016/j.humimm.2014.02.004.
  • Bode, S. F.; Ammann, S.; Al-Herz, W.; Bataneant, M.; Dvorak, C. C.; Gehring, S. et al. (2015): The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis. In: Haematologica 100 (7), S. 978–988. DOI: 10.3324/haematol.2014.121608.
  • Doganci, A.; Birkholz, J.; Gehring, S.; Puhl, A. G.; Zepp, F.; Meyer, C. U. (2013): In the presence of IL-21 human cord blood T cells differentiate to IL-10-producing Th1 but not Th17 or Th2 cells. In: Int Immunol 25 (3), S. 157–169. DOI: 10.1093/intimm/dxs097.
  • Du Prel, J. B.; Puppe, W.; Grondahl, B.; Knuf, M.; Weigl, J. A.; Schaaff, F.; Schmitt, H. J. (2009): Are meteorological parameters associated with acute respiratory tract infections? In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 49 (6), S. 861–868. DOI: 10.1086/605435.
  • Duwaerts, C. C.; Gehring, S.; Cheng, C. W.; van Rooijen, N.; Gregory, S. H. (2013): Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury. In: Liver Int 33 (2), S. 255–265. DOI: 10.1111/liv.12048.
  • Fichter, M.; Baier, G.; Dedters, M.; Pretsch, L.; Pietrzak-Nguyen, A.; Landfester, K.; Gehring, S. (2013): Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages. In: Nanomedicine 9 (8), S. 1223–1234. DOI: 10.1016/j.nano.2013.05.005.
  • Fichter, M.; Dedters, M.; Pietrzak-Nguyen, A.; Pretsch, L.; Meyer, C. U.; Strand, S. et al. (2015): Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage. In: Vaccine 33 (7), S. 838–846. DOI: 10.1016/j.vaccine.2014.12.072.
  • Gehring, S.; Dickson, E. M.; San Martin, M. E.; van Rooijen, N.; Papa, E. F.; Harty, M. W. et al. (2006): Kupffer cells abrogate cholestatic liver injury in mice. In: Gastroenterology 130 (3), S. 810–822. DOI: 10.1053/j.gastro.2005.11.015.
  • Gehring, S.; Gregory, S. H.; Wintermeyer, P.; San Martin, M.; Aloman, C.; Wands, J. R. (2008): Generation and characterization of an immunogenic dendritic cell population. In: J Immunol Methods 332 (1-2), S. 18–30. DOI: 10.1016/j.jim.2007.12.007.
  • Gehring, S.; Gregory, S. H.; Wintermeyer, P.; Aloman, C.; Wands, J. R. (2009): Generation of immune responses against hepatitis C virus by dendritic cells containing NS5 protein-coated microparticles. In: Clin Vaccine Immunol 16 (2), S. 163–171. DOI: 10.1128/CVI.00287-08.
  • Gehring, S.; Sabo, E.; San Martin, M. E.; Dickson, E. M.; Cheng, C. W.; Gregory, S. H. (2009): Laser capture microdissection and genetic analysis of carbon-labeled Kupffer cells. In: World J Gastroenterol 15 (14), S. 1708–1718.
  • Grondahl, B.; Ankermann, T.; Bismarck, P. von; Rockahr, S.; Kowalzik, F.; Gehring, S. et al. (2014): The 2009 pandemic influenza A(H1N1) coincides with changes in the epidemiology of other viral pathogens causing acute respiratory tract infections in children. In: Infection 42 (2), S. 303–308. DOI: 10.1007/s15010-013-0545-5.
  • Grondahl, B.; Puppe, W.; Hoppe, A.; Kuhne, I.; Weigl, J. A.; Schmitt, H. J. (1999): Rapid identification of nine microorganisms causing acute respiratory tract infections by single-tube multiplex reverse transcription-PCR: feasibility study. In: Journal of clinical microbiology 37 (1), S. 1–7.
  • Grondahl, B.; Puppe, W.; Weigl, J.; Schmitt, H. J. (2005): Comparison of the BD Directigen Flu A+B Kit and the Abbott TestPack RSV with a multiplex RT-PCR ELISA for rapid detection of influenza viruses and respiratory syncytial virus. In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 11 (10), S. 848–850. DOI: 10.1111/j.1469-0691.2005.01223.x.
  • Kalies, H.; Grote, V.; Siedler, A.; Grondahl, B.; Schmitt, H. J.; Kries, R. von (2008): Effectiveness of hexavalent vaccines against invasive Haemophilus influenzae type b disease: Germany's experience after 5 years of licensure. In: Vaccine 26 (20), S. 2545–2552. DOI: 10.1016/j.vaccine.2008.03.001.
  • Kalies, H.; Siedler, A.; Grondahl, B.; Grote, V.; Milde-Busch, A.; Kries, R. von (2009): Invasive Haemophilus influenzae infections in Germany: impact of non-type b serotypes in the post-vaccine era. In: BMC infectious diseases 9, S. 45. DOI: 10.1186/1471-2334-9-45.
  • Kidszun, A.; Hansmann, A.; Winter, J.; Grondahl, B.; Knuf, M.; Weise, K.; Mildenberger, E. (2014): Detection of respiratory viral infections in neonates treated for suspicion of nosocomial bacterial sepsis: a feasibility study. In: The Pediatric infectious disease journal 33 (1), S. 102–104. DOI: 10.1097/INF.0000000000000008.
  • Kidszun, A.; Klein, L.; Winter, J.; Schmeh, I.; Grondahl, B.; Gehring, S. et al. (2016): Viral Infections in Neonates with Suspected Late-Onset Bacterial Sepsis-A Prospective Cohort Study. In: American journal of perinatology. DOI: 10.1055/s-0036-1584150.
  • Meyer, C. U.; Birkholz, J.; Weins, N.; Doganci, A.; Gehring, S.; Zepp, F.; Knuf, M. (2015): Dendritic cells change IL-27 production pattern during childhood. In: BMC Res Notes 8, S. 232. DOI: 10.1186/s13104-015-1182-0.
  • Meyer, C. U.; Kurlemann, G.; Sauter, M.; Wiemer-Kruel, A.; Hahn, A.; Doganci, A. et al. (2015): Inflammatory Characteristics of Monocytes from Pediatric Patients with Tuberous Sclerosis. In: Neuropediatrics 46 (5), S. 335–343. DOI: 10.1055/s-0035-1562925.
  • Pietrzak-Nguyen, A.; Fichter, M.; Dedters, M.; Pretsch, L.; Gregory, S. H.; Meyer, C. et al. (2014): Enhanced in vivo targeting of murine nonparenchymal liver cells with monophosphoryl lipid A functionalized microcapsules. In: Biomacromolecules 15 (7), S. 2378–2388. DOI: 10.1021/bm5006728.
  • Piradashvili, K.; Fichter, M.; Mohr, K.; Gehring, S.; Wurm, F. R.; Landfester, K. (2015): Biodegradable protein nanocontainers. In: Biomacromolecules 16 (3), S. 815–821. DOI: 10.1021/bm5016915.
  • Puppe, W.; Weigl, J. A.; Aron, G.; Grondahl, B.; Schmitt, H. J.; Niesters, H. G.; Groen, J. (2004): Evaluation of a multiplex reverse transcriptase PCR ELISA for the detection of nine respiratory tract pathogens. In: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 30 (2), S. 165–174. DOI: 10.1016/j.jcv.2003.10.003.
  • Puppe, W.; Weigl, J.; Grondahl, B.; Knuf, M.; Rockahr, S.; Bismarck, P. von et al. (2013): Validation of a multiplex reverse transcriptase PCR ELISA for the detection of 19 respiratory tract pathogens. In: Infection 41 (1), S. 77–91. DOI: 10.1007/s15010-012-0298-6.
  • Schmitt, Heinz-J.; Gröndahl, Britta; Schaaff, Franziska; Puppe, Wolfram (2007): The beginning of a new era. Systematic testing for pathogens causing acute respiratory tract infections (ARI) in children. In: J Pediatr (Rio J) 83 (5), S. 391–394. DOI: 10.2223/JPED.1701.
  • Weigl, J. A.; Puppe, W.; Grondahl, B.; Schmitt, H. J. (2000): Epidemiological investigation of nine respiratory pathogens in hospitalized children in Germany using multiplex reverse-transcriptase polymerase chain reaction. In: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19 (5), S. 336–343.
  • Wintermeyer, P.; Cheng, C. W.; Gehring, S.; Hoffman, B. L.; Holub, M.; Brossay, L.; Gregory, S. H. (2009): Invariant natural killer T cells suppress the neutrophil inflammatory response in a mouse model of cholestatic liver damage. In: Gastroenterology 136 (3), S. 1048–1059. DOI: 10.1053/j.gastro.2008.10.027.
Klinik und Poliklinik für Kinder- und Jugendmedizin

Universitätsmedizin Mainz
Klinik und Poliklinik für Kinder- und Jugendmedizin

Langenbeckstr. 1

55131 Mainz

Tel.: 06131 17-2557

AG Pädiatrische Immunologie und Impfstoffentwicklung

Klinik und Poliklinik für Kinder- und Jugendmedizin
Labor für Pädiatrische Immunologie

Universitätsmedizin Mainz
Verfügungsgebäude 911/R.01-336
Obere Zahlbacher Str. 63
55131 Mainz

Tel.: +49 6131 17-9753
Fax: +49 6131 17-9658