Clinical Pharmacology and Pharmacogenetics

Dr. Marianne Mathäs and Univ.- Prof. Dr. Leszek Wojnowski deal with the field of clinical pharmacology and pharmacogenetics with a focus on:

• The transmission of adverse drug reactions, such as toxicities and disease dispositions to subsequent generations.
  DFG-project

• The importance of transcription profiles for individualization of cancer treatments, especially with topoisomerase II inhibitors in acute myeloid leukemia.
  DFG-project

• The development of IT tools Pharmafrog, Rheuma-VOR, How to prescribe correctly? to improve the safety and understanding of pharmacotherapy.

Frequently used methods:

Molecular biology (PCR, gel electrophoresis, cloning, quantitative PCR), cell culture (transfection, reporter gene assay), Western blot, high throughput data analysis, mouse models, machine learning, appcode programming

Our publications with altogether over 8000 Google Scholar Citations

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Research Associate

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