Visual Universitätsmedizin Mainz

Publikationen AG Prof. Simon Rumpel




Anna R Chambers, Dominik F Aschauer, Jens-Bastian Eppler, Matthias Kaschube, Simon Rumpel (2022) A stable sensory map emerges from a dynamic equilibrium of neurons with unstable tuning properties. Cerebral Cortex, bhac445 

Seiler JPH, Dan O, Tüscher O, Loewenstein Y, Rumpel S (2022) Experienced entropy drives choice behavior in a boring decision-making task. Scientific reports, 12:3162.

Aschauer DF, Eppler JB, Ewig L, Chambers AR, Pokorny C, Kaschube M, Rumpel S (2022) Learning-induced biases in the ongoing dynamics of sensory representations predict stimulus generalization. Cell Reports, 38:110340.

Peter M, Aschauer DF, Rose R, Sinning A, Grössl F, Kargl D, Kraitsy K, Burkard TR, Luhmann HJ, Haubensak W, Rumpel S (2021) Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation. PLoS ONE. 16: e0244038.

Ceballo S, Bourg J, Kempf A, Piwkowska Z, Daret A, Pinson P, Deneux T, Rumpel S & Bathellier B (2019) Cortical recruitment determines learning dynamics and strategy. Nat. Commun. 10:1479.

Mongillo G, Rumpel S, Loewenstein Y (2018) Inhibitory connectivity defines the realm of excitatory plasticity. Nat. Neurosci. 21:1463–1470.

Loewenstein Y, Yanover U, Rumpel S (2015) Predicting the dynamics of network connectivity in the neocortex. J. Neurosci., 35:12535-12544.

Moczulska KE, Pichler P, Schutzbier M, Schleiffer A, Rumpel S, Mechtler K (2014) Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation. J. Proteome Res., 13: 4310-4324. 

Bathellier B, Tee SP, Hrovat C, Rumpel S (2013) A multiplicative reinforcement learning model capturing learning dynamics and inter-individual variability in mice. Proc. Natl. Acad. Sci. USA 110:19950-19955.

Moczulska KE, Tinter-Thiede J, Peter M, Ushakova L, Wernle T, Bathellier B, Rumpel S (2013) Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall. Proc. Natl. Acad. Sci. USA 110:18315-18320.

Aschauer DF, Kreuz S, Rumpel S (2013) Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain. PLoS One. 2013 8:e76310.

Fischer RM, Fontinha BM, Kirchmaier S, Steger J, Bloch S, Panda S, Rumpel S, Tessmar-Raible K (2013) Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain. PloS Biol. 11:e1001585.

Peter M, Bathellier B, Fontinha B, Pliota P, Haubensak W, Rumpel S (2013) Transgenic mouse models enabling photolabeling of individual neurons in vivo. PLoS ONE 8:e62132.

Bathellier B, Ushakova L, Rumpel S (2012) Discrete Neocortical Dynamics Predict Behavioral Categorization of Sounds. Neuron 76:435-449. (discussed in: Harris KD (2012) Cell assemblies of the superficial cortex. Neuron, 76:263-265.)

Peter M, Scheuch H, Burkard TR, Tinter J, Wernle T, Rumpel S (2012) Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds. Genes Brain Behav. 11:314-324.

Loewenstein Y, Kuras A, Rumpel S (2011) Multiplicative dynamics underlies the emergence of the log-normal distribution of spine sizes in the neocortex in vivo. J. Neurosci. 31:9481-9488.

Ehrlich I, Klein M, Rumpel S, Malinow R (2007) PSD-95 is required for activity-driven synapse stabilization. Proc. Natl. Acad. Sci. USA 104:4176-4181.

Rumpel S, LeDoux J, Zador A, Malinow R (2005) Postsynaptic receptor trafficking underlying amygdala associative learning. Science 308:83-88 (discussed in: Maren S (2005) Synaptic mechanisms of associative memory in the amygdala. Neuron, 47:783-786; Ehninger D, Matynia A, Silva AJ (2005) Trafficking in emotions. Nat. Neurosci., 8:548-550.)

Rumpel S, Kattenstroth G, Gottmann K (2004) Silent synapses in the immature visual cortex: layer-specific developmental regulation. J. Neurophysiol. 91:1097-1101. 

Plitzko D, Rumpel S, Gottmann K. (2001) Insulin promotes functional induction of silent synapses in differentiating neocortical neurons. Eur. J. Neuroscience, 14:1412-1415. 

Rumpel S, Hoffmann H, Hatt H, Gottmann K, Mittmann T, Eysel UT (2000) Lesion-induced changes in NMDA receptor subunit mRNA expression in rat visual cortex. NeuroReport, 11:4021-4025. 

Rumpel S, Hatt H, Gottmann K (1998) Silent synapses in the developing rat visual cortex: evidence for postsynaptic expression of synaptic plasticity. J. Neurosci., 18:8863-8874. 

Andere Publikationen

Chan Y-C, Kienle E, Oti M, Di Liddo A, Mendez-Lago M, Aschauer DF, Peter M, Pagani M, Arnold C, Vonderheit A, Schön C, Kreuz S, Stark A, Rumpel S (2022), An unbiased AAV-STARR-Seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo. Sci Rep 13, 6745 (2023).

Aschauer DF, Eppler JB, Ewig L, Chambers A, Pokorny C, Kaschube M, Rumpel S (2019) A Basis Set of Elementary Operations Captures Recombination of Neocortical Cell Assemblies During Basal Conditions and Learning. 

Rumpel S (2018) Supporting recovery from brain injury. Science, 360:30-31.

Aschauer D, Rumpel S (2018) The sensory neocortex and associative memory. Curr. Top. Behav. Neurosci 37:177-211

Chambers AR, Rumpel S (2017) A stable brain from unstable components: Emerging concepts and implications for neural computation. Neuroscience, 357:172-184

Mongillo G, Rumpel S, Loewenstein Y (2017) Intrinsic volatility of synaptic connections — a challenge to the synaptic trace theory of memory. Curr. Opin. Neurobiol. 46:7–13

Rumpel S, Triesch J (2016) The dynamic connectome. e-Neuroforum 7:48-53

Aschauer DF, Rumpel S (2014) Measuring the Functional Organization of the Neocortex at Large and Small Scales. Neuron, 83:756-758