Visual Universitätsmedizin Mainz


1.    Schuppan D, Dillon S, Liberman T, Popov Y. Biomarkers of liver fibrogenesis and fibrolysis to assess antifibrotic drug effects. US patent. 2014 Jan 10.

2.    Schuppan D, Zevallos V. Methods for determination of bioactivity, removal, or inactivation of cereal amylase trypsin inhibitors in cereals, flours and complex foods. US patent. 2014 May 8.

3.    Schuppan D, Popov Y, Kornek M, inventors. Beth Israel Deaconess Medical Center, assignee. T cell derived microparticles: A diagnostic therapeutic tool for inflammation. US patent. 2010 June 28.

4.    Schuppan D, Junker Y, Libermann T, Dillon S, inventors. Beth Israel Deaconess Medical Center, assignee. A non-gluten component of wheat and related cereals as trigger of innate immune activation: use for diagnosis and treatment of intestinal inflammation. US patent. 2010 April 30.

5.    Schuppan D, Frangioni JV, Popov Y, Misra P, inventors. Beth Israel Deaconess Medical Center, assignee. Methodology to quantitatively image fibogenesis in the liver and other organs. US patent. 2007 Aug 23.

6.    Schuppan D, Freitag T, Sonderstrup G, inventors; BIDMC and Stanford Univ, assignee. Mouse model for celiac disease. US patentEV 919934295 US. 2006 Mar 23.

7.    Schuppan D, Popov Y, Patsenker E, Jonczyk A, Wiesner M, Goodman S, inventors; Merck Pharma, Darmstadt, Germany, assignee. AlfaVbeta3 and alfaVbeta6 antagonists as antifibrotic agents. Worldwide patent WO2005/039547. 2005 May 6.

8.    Schuppan D, Herold C, Ganslmayer M, Tierauch G, Laurent D, inventors; Schering Pharma, Berlin, Germany, assignee. Pharmaceutical combinations and their use for the treatment of diseases resulting from persistent angiogenesis. European patent EPC 03090061.7, 2003 March 12.

9.    Ocker M, Herold C, Geick A, Schuppan D, Vornlocher HP, Kreutzer R, Limmer S, inventors; Ribopharma/Alnaypharma, Ribopharma, Kulmbach, Germany / Alnylam, Cambridge, MA, USA, assignee. Drug for treating a carcinoma of the pancreas. Worldwide patent PCT WO 03/035070 A1. 2003 May 1.

10. Kreutzer R, Limmer S, Schuppan D, John M, Bauer M, inventors; Ribopharma, Kulmbach, Germany /Alnylam, Cambridge, MA, USA, assignee. Drug for treating a fibrotic disease through RNA interference. Worldwide patent PCT WO 03/035083 A1. 2003 May 1.

11. Krebs A, Schuppan D, Limmer S, Kreutzer R., inventors; Ribopharma, Kulmbach, Germany/ Alnylam, Cambridge, MA, USA, assignee. Use of a double strand ribonucleic acid for treating an infection with a positive strand RNA virus. Worldwide patent PCT WO 03/035876 A1. 2003 May 1.

12. Bergmann A, Willnich M, Schuppan D, inventors; Brahms diagnostics, Henningsdorf/Berlin, Germany, assignee. Novel methods for diagnosis and therapy of inflammatory bowel diseases. Worldwide patent PCT WO 03/029824 A1. 2003 Apr 10.

13. Schuppan D, Raschack M, inventors. Knoll-BASF Pharma, Mannheim, Germany, assignee. Use of endothelin inhibitors for treatment or prevention of fibrotic disorders. US patent US 2002/0098186 A1. 2002 July 25.

14. Kreutzer R, Limmer S, Vornlocher HP, Hadwiger P, Geick A, Ocker M, Herold C, Schuppan D, inventors; Ribopharma, Kulmbach, Germany / Alnylam, Cambridge, MA, USA, assignee. Method for inhibiting the expression of a target gene and medicament for treating a tumor disease. Worldwide patent PCT WO 02/055692 A2. 2002 Jul 18.

15. Voelker M, Becka M, Kroll W, Knorr A, Unger S, Gehrmann M, Hennig G, Burchhardt E, Arthur MJP, Burt AD, Pinzani M, Schuppan D, inventors; Bayer Pharma, Leverkusen, Germany, assignee. Diagnosis of liver fibrosis with serum marker algorithms. Worldwide patent PCT WO 01/86304 A2. 2001 Nov 15.

16. Poelstra K, Beljaars L, Meijer DKF, Schuppan D, inventors; Univ. of Groningen, NL, assignee. Peptide derived carrier devices for stellate cells. Worldwide patent PCT WO 00/23113.
2000 April 27.

17. Poelstra K, Beljaars L, Schuppan D, Meijer DKF, inventors. Peptide-based carrier devices for stellate cells and other cell-types involved in chronic inflammatory and fibrotic disorders. Worldwide patent PCT/NL98/00579. 1998, Oct.

18. Schuppan D, Dieterich W, Ehnis T, inventors; Schuppan D, Dieterich W, assignee. Immunological process for detecting antibodies directed against tissue transglutaminase (tTG), use of tTG for diagnostic purposes and therapy control, and oral phamacological agent containing tTG. Worldwide patent PCT WO 98/03872 A2. 1998 Jan 29.

19. Schuppan D, Hahn EG, inventors; Heyl Pharma, Berlin, Germany, assignee. Undulin and its fragmentation products, production process and utilization thereof. Worldwide patent PCT WO 87/00176. 1987 Jan 15.