Publikationen 2025
Kaina B., Christmann C. (2025) Senotherapeutics in malignant brain cancer therapy, Current Oncology Reports, epub ahead of print
Ashry R., Krämer O.H. (2025) News and views: lysine sorbylation enters the expanding universe of posttranslational modifications, Archives of Toxicology, 99, 5123-5127
Ashry R., Abdelsalam M., Hausen J., Hieber C., Zeyn Z., Sarnow A.-C., Schmidt M., Najafi S., Oehme I., Bros M., Chen J.-X., Dejung M., Sippl W., Krämer O.H. (2025) Identification of a proteolysis-targeting chimera that addresses activated checkpoint kinase-1 reveals its non-catalytic functions in tumor cells, Angewandte Chemie, Int. Ed., e202514788
Adardour M., M. Mustafa Al-Hassan, Oubahmane M., Lahcen M.A., Seif E.M., Ezzat M.A.F., Zaballos-García E., Mague J.T., Hdoufane I., Cherqaoui D., Krämer O.H., Sippl W., Ibrahim H.S., Baouid A. (2025) Design, synthesis and molecular modeling of new pyrazolyl-Benzimidazolone hybrids targeting breast cancer, Bioorganic Chemistry,. vol. 157, 108269
Jungwirth J., Siegert L., Gauthier L., Henke A., Krämer O.H., Engert B., Ehrhardt C. (2025) The procaine-based procluster impedes the second envelopment process of herpes simplex virus type 1, International Journal of Molecular Sciences, 26, 7185
Mieland A.O., Petrosino G., Dejung M., Chen J.-X., Fulzele A., Mahmoudi F.,Tu J.-W., M. Mustafa Al-Hassan, Zeyn Y., Hieber C., Bros M., Schnöder T.M., Heidel F.H., Najafi S., Oehme I., Hofmann I., Schutkowski M:, Hilscher S., Kosan C., Butter F., Bhatia S., Sippl W., Krämer O.H. (2025) The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells, Leukemia, Springer Nature
M. Mustafa Al-Hassan, Petrosino G., Fischer M.A., Schnöder T.M., Gül D., Zeyn Y., Hieber C., Lossa J., Muth S., Radsak M.P., Brenner W., Christmann M., Bros M., Heidel F.H., Krämer O.H. (2025) The deacetylases HDAC1/HDAC2 control JAK2V617F-STAT signaling though the ubiuitin ligase SIAH2, Signal Transduction and Targeted Therapy, Springer Nature
Ackermann G., Peil M., Quarz C., Schmidt A., Halaczkiewicz M., Thomas A.D., Stegmüller S., Richling E., Manolikakes G., Christmann M., Küpper J.H., Schrenk D., Fahrer J. (2025) Molecular dosimetry of estragole and 1'-hydroxyestragole-induced DNA adduct formation, clastogenicity and cytotoxicity in human liver cell models, Archives of Toxicology, pub ahead of print
Switzeny O., Pusch S., Christmann M., Kaina B. (2025) IDH1 mutation impacts DNA repair through ALKBH2 rendering glioblastoma cells sensitive to artesunate, Biomedicines, 13, 1479
Schwarzenbach C., Rinke j., Vilar J.B., Sallbach J., Tatsch L., Schmidt A., Schöneis A., Rasenberger B., Kaina B., Tomicic M.T., Christmann M. (2025) Therapy-induced senescence of glioblastoma cells is determined by the p21cip1-CDK1/2 axis and does not require activation of DREAM, CDD press Springer Nature, (pub ahead of print).
Jungwirth J., Mieland A.O., Piée-Staffa A., Heimburg T., Brenner W., Ehrhardt C., Sippl W., Henke A., Krämer O.H. (2025) Pharmacologically induced proteolysis of histone deacetylase-6 attenuates influenza virus replication despite limited anti-tumor effects, Life Sciences (e-pub ahead of print).
Haas B., Roth I., Säcker L., Wos-Maganga M., Beltzig L., Kaina B. (2025) Apoptotic and senolytic effects of hERG/Eag1 channel blockers in combination with temozolomide in human glioblastoma cells, Naunyn-Schmiedeberg's Archives of Pharmacology (e-pub ahead of print).
Fincke V.E., Sax I., Kunstreich M., Golas M.M., Hofmann T.G., Schlesner M., Claus R., Redlich A., Johann P.D., Kuhlen M. (2025) Double heterozygous pathogenic variants in BRCA2 and CHEK2 in a girl with adrenocortical carcinoma, Exploration of Endocrine and Metabolic Diseases, 2: 101429