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BMBF Projects

The BMBF (Federal Ministry of Education and Research - Bundesministerium für Bildung und Forschung) supports basic and health research in many ways, e.g. by funding collaborative projects and by funding German Centers for Health Research (DZG).

The CTH is involved in research projects of the following collaborative projects and German Centers for Health Research:

curATime - Future Cluster

'Future Clusters' of the BMBF aim to create innovations of the future from excellent basic research and through the regional bundling of different perspectives and competencies.

The cluster concept curATime, jointly developed by TRON gGmbH, Mainz, the University Medical Center Mainz (UM) and the German Research Center for Artificial Intelligence (DFKI), addresses the challenges of atherothrombosis-related cardiovascular diseases with the aim of developing tailored treatment and prevention concepts for cardiovascular diseases and their clinical application.

Research groups of the CTH are involved in the following projects within curATime:

Summary curATime:

  • Titel: curATime – Cluster for Atherothrombosis and Individualised Medicine
  • Clusterpartners: TRON gGmbH Mainz, DFKI Kaiserslautern, UM Mainz
  • Duration: 2023-2026
  • Further informationen: curATime | Clusters4Future

DZHK

The DZHK (German Center for Cardiovascular Research - Deutsches Zentrum für Herz- und Kreislaufforschung e.V.) is one of a total of six German Centers for Health Research dedicated to research into common diseases and was founded on the initiative of the BMBF .

The DZHK aims to develop therapies and diagnostic procedures for cardiovascular diseases. To this end, results from basic research are to be applied quickly and in a targeted manner. To this end, the DZHK combines outstanding basic research and clinical research from seven locations in Germany, creating synergies and accelerating the process of translation. The CTH has been continuously involved in research projects of the DZHK since its foundation: Current projects:

  • 1808: The gut microbiome as a functional modifier of myelopoiesis and inflammatory vascular endothelial phenotypes in cardiometabolic disease

Past projects:

  • 1520: The microbial effect on thrombus growth and platelet function in a deep vein thrombosis model (Dr. Klytaimnistra Kiouptsi)
  • 1567: Prothrombotic mechanisms of autoimmune antibodies in COVID-19 (Prof. Wolfram Ruf)
  • 1568: The role of thrombogenic autoantibodies in cardiovascular sequelae of post-acute COVID-19 syndrome (Prof. Wolfram Ruf)
  • 1382: Platelet signatures in hypertension: from mouse to man (Prof. Wolfram Ruf)
  • 1207: Thrombo-inflammatory responses of monocytes in antiphospholipid syndrome (Prof. Wolfram Ruf)
  • 704: The role of monocytic CRIP1 of renal function and blood pressure regulation (Prof. Wolfram Ruf)
  • 128: Analysis of PAR2 mouse mutants to specify the role of PAR2 in viral myocarditis (Prof. Wolfram Ruf)
  • 125: Analyses on the impact of the intestinal microbiota on atherosclerotic plaque development, plaque rupture and atherothrombosis (Prof. Christoph Reinhardt)
  • 1313: Clinical applications of human platelet proteomics and phosphoproteomics (Prof. Ulrich Walter)

Summary DZHK:

  • DZHK - Deutsches Zentrum für Herz- und Kreislaufforschung e.V.
  • Locations: Berlin, Göttingen, Greifswald, Hamburg/Kiel/Lübeck/, Heidelberg/Mannheim, Munich, RheinMain
  • Further information: DZHK | German Centers for Health Research

DKTK

The DKTK (German Cancer Consortium - Deutsches Konsortium für translationale Krebsforschung) is also one of a total of six German Centers for Health Research dedicated to research into common diseases and was founded on the initiative of the BMBF.

The DKTK aims to develop new strategies for personalized oncology and bring them into clinical application. To this end, the DKTK promotes interdisciplinary research topics at the interface between basic research and clinical practice, as well as clinical trials of innovative therapeutic and diagnostic methods.

Research groups and individuals of the CTH have been involved in research projects of the DZHK since its foundation.

Summary DKTK:

  • DKTK - German Cancer Consortium - Deutsches Konsortium für translationale Krebsforschung
  • Locations: Berlin, Dresden, Essen/Düsseldorf, Frankfurt/Mainz, Freiburg, Heidelberg, Munich, Tübingen
  • Further information: DKTK | German Centers for Health Research