Juniorprofessorship 'Systems Interactions of Hemostasis'

Assistant Professor for Systems Interactions of Hemostasis

Jun. Prof. Dr. Carsten Deppermann

Platelets are small, anucleate cells that patrol the vasculature to immediately respond to vessel breaches and restore hemostasis. There has been accumulating evidence that platelets also interact with and regulate cells of the (innate) immune system. It is now accepted that they play roles beyond hemostasis and contribute to thromboinflammatory processes in disease.

We are currently employing intravital microscopy, tissue clearing, primary cell culture, flow cytometry and other state-of-the-art techniques to understand the complex interplay between platelets and the innate immune system in the liver, kidney and intestine under (patho)physiologic conditions. We are also studying the mechanisms through which platelet clearance in health and disease feeds back to platelet production by megakaryocytes in the bone marrow.

Research Funding


Biography - Carsten Deppermann

Positions:
Since 2021 – Assistant Professor for Systems Interactions of Hemostasis, CTH, University Medical Center of the Johannes Gutenberg-University, Mainz
2019 - 2021 – Group Leader, Institute of Clinical Chemistry and Laboratory Medicine, University Medical Centre Hamburg-Eppendorf

Research Career:
2016 - 2019 – Postdoctoral Fellow (with Prof. Dr. Paul Kubes), Snyder Institute for Chronic Diseases, Calgary, Canada, DFG Research Fellowship

Professional Education:
2011 - 2015 – PhD, Experimental Biomedicine, Rudolf Virchow Centre, Würzburg, Supervisor Prof. Dr. Bernhard Nieswandt
2005 - 2010 – Studies in Biochemistry, University of Frankfurt/Main, Master (Diplom), Thesis Supervisor Prof. Dr. Mirko Schmidt

Researcher IDs:
ORCID: 0000-0003-3740-8635
Google Scholar: Link

Twitter:
Link

Team - Juniorprofessorship Systems Interactions of Hemostasis

Jun. Prof. Dr. Carsten Deppermann

Jun. Prof. Dr. Carsten Deppermann

Juniorgroup leader

 Olga An

Olga An

PhD Student

 Martina Casari

Martina Casari

PhD Student

 Emma Gerhold

Emma Gerhold

PhD Student

PhD Viola Krenzlin

PhD Viola Krenzlin

Lab Manager

 Bettina Mros

Bettina Mros

Technician

 Luna Rauer

Luna Rauer

Dr. Friedrich Reusswig

Dr. Friedrich Reusswig

Postdoc

We are currently looking for motivated Master, MD or PhD students. Students with interests in platelet/cell biology, innate immunity and microscopy are encouraged to apply via e-mail to deppermann@uni-mainz.de including a letter of motivation and CV.

Original articles

Reviews

October 2023

Carsten Deppermann receives highly competetive Emmy Noether Funding

July 2022

curATime funded by the Federal Ministry of Education and Research (BMBF). Press Release

November 2021

Collaborative Research Center (CRC) 1292 'Targeting convergent mechanisms of inefficient immunity in tumors and chronic infections' started 2nd funding round. Press Release