The CTH platform for translational research (Clinical Trial Platform) includes the CTH patient registry, the CTH research database and the CTH biobank and thus forms the basis for all clinical studies within the CTH. High quality research on health service is of particular interest. Examples of such research include head-to-head studies used to investigate whether well-established therapies/medication have the same or similar effects in the "real world" and also evaluations of existing treatment concepts. These studies are of great interest for the quality and cost efficiency of medical treatment within health care systems and therefore are the center of attention for the CTH.