Visual Universitätsmedizin Mainz

Publikationen AG Moosmann

  • Moosmann B (2011). Respiratory chain cysteine and methionine usage indicate a causal role for thiyl radicals in aging. Exp. Gerontol. 46, 164-169.

  • Ohlow MJ, Moosmann B (2011). Phenothiazine: The seven lives of pharmacology’s first lead structure. Drug Discov. Today 16, 119-131.

  • Schindeldecker M, Stark M, Behl C, Moosmann B (2011). Differential cysteine depletion in respiratory chain complexes enables the distinction of longevity from aerobicity. Mech. Ageing Dev. 132, 171-179.

  • Meng F, Yao D, Shi Y, Kabakoff J, Wu W, Reicher J, Ma Y, Moosmann B, Masliah E, Lipton SA, Gu Z (2011). Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation. Mol. Neurodegener. 6, 34.

  • Ohlow MJ, Granold M, Schreckenberger M, Moosmann B (2012). Is the chromanol head group of vitamin E nature’s final truth on chain-breaking antioxidants? FEBS Lett. 586, 711-716.

  • Fuhrmeister J, Tews M, Kromer A, Moosmann B (2012). Prooxidative toxicity and selenoprotein suppression by cerivastatin in muscle cells. Toxicol. Lett. 215, 219-227.

  • Liebl MP, Kaya AM, Tenzer S, Mittenzwei R, Koziollek-Drechsler I, Schild H, Moosmann B, Behl C, Clement AM (2014). Dimerization of visinin-like protein 1 is regulated by oxidative stress and calcium and is a pathological hallmark of amyotrophic lateral sclerosis. Free Radic. Biol. Med. 72, 41-54.

  • Spang N, Feldmann A, Huesmann H, Bekbulat F, Schmitt V, Hiebel C, Koziollek-Drechsler I, Clement AM, Moosmann B, Jung J, Behrends C, Dikic I, Kern A, Behl C (2014). RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy. Autophagy 10, 2297-2309.

  • Songarj P, Luh C, Staib-Lasarzik I, Engelhard K, Moosmann B, Thal SC (2015). The antioxidative, non-psychoactive tricyclic phenothiazine reduces brain damage after experimental traumatic brain injury in mice. Neurosci. Lett. 584, 253-258.

  • Granold M, Moosmann B, Staib-Lasarzik I, Arendt T, del Rey A, Engelhard K, Behl C, Hajieva P (2015). High membrane protein oxidation in the human cerebral cortex. Redox Biol. 4, 200-207.

  • Hartmann EK, Ziebart A, Thomas R, Liu T, Schad A, Tews M, Moosmann B, Kamuf J, Duenges B, Thal SC, David M (2015). Inhalation therapy with the synthetic TIP-like peptide AP318 attenuates pulmonary inflammation in a porcine sepsis model. BMC Pulm. Med. 15, 7.

  • Hajieva P, Bayatti N, Granold M, Behl C, Moosmann B (2015). Membrane protein oxidation determines neuronal degeneration. J. Neurochem. 133, 352-367.

  • Schindeldecker M, Moosmann B (2015). Protein-borne methionine residues as structural antioxidants in mitochondria. Amino Acids 47, 1421-1432.

  • Hajieva P, Moosmann B (2015). Brain protein oxidation: what does it reflect? Neural Regen. Res. 10, 1729-1730.

  • Sebastiani A, Granold M, Ditter A, Sebastiani P, Gölz C, Pöttker B, Luh C, Schaible EV, Radyushkin K, Timaru-Kast R, Werner C, Schäfer MK, Engelhard K, Moosmann B, Thal SC (2016). Posttraumatic propofol neurotoxicity is mediated via the proBDNF-p75NTR pathway in adult mice. Crit. Care Med. 44, e70-e82.

  • Ohlow MJ, Sohre S, Granold M, Schreckenberger M, Moosmann B (2017). Why have clinical trials of antioxidants to prevent neurodegeneration failed? - A cellular investigation of novel phenothiazine-type antioxidants reveals competing objectives for pharmaceutical neuroprotection. Pharm. Res. 34, 378-393.

  • Moosmann B (2017). Redoxbiochemie des genetischen Codes. Biospektrum 23, 748-751.

  • Granold M, Hajieva P, Tosa M, Irimie FD, Moosmann B (2018). Modern diversification of the amino acid repertoire driven by oxygen. Proc. Natl. Acad. Sci. USA 115, 41-46.

  • Hajieva P, Baeken MW, Moosmann B (2018). The role of Plasma Membrane Calcium ATPases (PMCAs) in neurodegenerative disorders. Neurosci. Lett. 663, 29-38.

  • Neulen A, Pantel T, Kosterhon M, Kramer A, Kunath S, Petermeyer M, Moosmann B, Lotz J, Kantelhardt SR, Ringel F, Thal SC (2019). Neutrophils mediate early cerebral cortical hypoperfusion in a murine model of subarachnoid hemorrhage. Sci. Rep. 9, 8460.

  • Kunath S, Moosmann B (2020). What is the rate-limiting step towards aging? – Chemical reaction kinetics might reconcile contradictory observations in experimental aging research. Geroscience 42, 857-866.

  • Moosmann B, Schindeldecker M, Hajieva P (2020). Cysteine, glutathione and a new genetic code: Biochemical adaptations of the primordial cells to spread into the open water and survive biospheric oxygenation. Biol. Chem. 401, 213-231.

  • Baeken MW, Moosmann B, Hajieva P (2020). Retrotransposon activation by distressed mitochondria in neurons. Biochem. Biophys. Res. Commun. 525, 570-575.

  • Kunath S, Schindeldecker M, De Giacomo A, Meyer T, Sohre S, Hajieva P, von Schacky C, Urban J, Moosmann B (2020). Prooxidative chain transfer activity by thiol groups in biological systems. Redox Biol. 36, 101628.

  • Baeken MW, Weckmann K, Diefenthäler P, Schulte J, Yusifli K, Moosmann B, Behl C, Hajieva P (2020). Novel insights into the cellular localization and regulation of the autophagosomal proteins LC3A, LC3B and LC3C. Cells 9, 2315.

  • Moosmann B (2021). Redox biochemistry of the genetic code. Trends Biochem. Sci. 46, 83-86.

  • Moosmann B (2021). Flux control in the aging cascade. Aging 13, 6233-6235.

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz (2021). Prooxidative chain-transfer agents for use in the treatment of malignant tumour or infectious diseases. PCT Int. Appl. (2021), 44 pp., WO 2021/105435.