Arterial thrombosis is caused by injury of the vascular endothelium or by rupture of atherosclerotic plaques. Consequences can be myocardial infarction or stroke, these are major causes of death worldwide.
One main cause of venous thrombosis is a reduction of blood flow caused by immobility after surgery or during long flights and train journeys. Blood clots often develop in the deep vein legs (deep venous thrombosis, DVT). These clots can break off from vein walls and travel to the lungs, where they can cause a pulmonary embolism.