Publikationen des Instituts für Mikrobiologie und Hygiene

 

2024

Almeida L, Dhillon-LaBrooy A, Sparwasser T. The evolutionary tug-of-war of macrophage metabolism during bacterial infection. Trends Endocrinol Metab. 2024;35(3):235-248. doi:10.1016/j.tem.2023.11.002

Caenepeel C, Falony G, Machiels K, et al. Dysbiosis and Associated Stool Features Improve Prediction of Response to Biological Therapy in Inflammatory Bowel Disease. Gastroenterology. 2024;166(3):483-495. doi:10.1053/j.gastro.2023.11.304

Caenepeel C, Deleu S, Vazquez Castellanos JF, et al. Rigorous Donor Selection for Fecal Microbiota Transplantation in Active Ulcerative Colitis: Key Lessons From a Randomized Controlled Trial Halted for Futility. Clin Gastroenterol Hepatol. Published online May 23, 2024. doi:10.1016/j.cgh.2024.05.017

Dhillon-LaBrooy A, Braband KL, Tantawy E, et al. Inhibition of Mitochondrial Translation Ameliorates Imiquimod-Induced Psoriasis-Like Skin Inflammation by Targeting Vγ4+ γδ T Cells. J Invest Dermatol. 2024;144(4):844-854.e2. doi:10.1016/j.jid.2023.09.275

Loreti S, Thiele K, De Brucker M, et al. Oral dydrogesterone versus micronized vaginal progesterone for luteal phase support: a double-blind crossover study investigating pharmacokinetics and impact on the endometrium. Hum Reprod. 2024;39(2):403-412. doi:10.1093/humrep/dead256

Midlej V, Tenaglia AH, Luján HD, de Souza W. Tunneling Nanotube-like Structures in Giardia duodenalis. Cells. 2024;13(18):1538. Published 2024 Sep 13. doi:10.3390/cells13181538

Poppe J, Boesmans L, Vieira-Silva S, et al. Differential contributions of the gut microbiota and metabolome to pathomechanisms in ulcerative colitis: an in vitro analysis. Gut Microbes. 2024;16(1):2424913. doi:10.1080/19490976.2024.2424913

Zhou Y, Wang X, Yin W, et al. Perioperative stroke deteriorates white matter integrity by enhancing cytotoxic CD8⁺ T-cell activation. CNS Neurosci Ther. 2024;30(7):e14747. doi:10.1111/cns.14747

 

2023

Andrikopoulos P, Aron-Wisnewsky J, Chakaroun R, et al. Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide. Nat Commun. 2023;14(1):5843. Published 2023 Sep 20. doi:10.1038/s41467-023-39824-4

Damasceno LEA, Cunha TM, Cunha FQ, Sparwasser T, Alves-Filho JC. A clinically-relevant STING agonist restrains human T_H17 cell inflammatory profile. Int Immunopharmacol. 2023;124(Pt B):111007. doi:10.1016/j.intimp.2023.111007

Devolder L, Pauwels A, Van Remoortel A, et al. Gut microbiome composition is associated with long-term disability worsening in multiple sclerosis. Gut Microbes. 2023;15(1):2180316. doi:10.1080/19490976.2023.2180316

Fan Y, Støving RK, Berreira Ibraim S, et al. The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice. Nat Microbiol. 2023;8(5):787-802. doi:10.1038/s41564-023-01355-5

Griemert T, Siegel E, Brandstetter M, et al. Entamoeba histolytica-associated proctitis and ileitis mimicking Crohn's disease-A case report. Clin Case Rep. 2023;11(5):e6833. Published 2023 May 20. doi:10.1002/ccr3.6833

Jansen D, Falony G, Vieira-Silva S, et al. Community Types of the Human Gut Virome are Associated with Endoscopic Outcome in Ulcerative Colitis. J Crohns Colitis. 2023;17(9):1504-1513. doi:10.1093/ecco-jcc/jjad061

Kao YS, Mamareli P, Dhillon-LaBrooy A, et al. Targeting ACC1 in T cells ameliorates psoriatic skin inflammation. J Mol Med (Berl). 2023;101(9):1153-1166. doi:10.1007/s00109-023-02349-w

Poppe J, Vieira-Silva S, Raes J, Verbeke K, Falony G. Systematic optimization of fermentation conditions for in vitro fermentations with fecal inocula. Front Microbiol. 2023;14:1198903. Published 2023 Jul 24. doi:10.3389/fmicb.2023.1198903

Ritter K, Vetter D, Wernersbach I, Schwanz T, Hummel R, Schäfer MKE. Pre-traumatic antibiotic-induced microbial depletion reduces neuroinflammation in acute murine traumatic brain injury. Neuropharmacology. 2023;237:109648. doi:10.1016/j.neuropharm.2023.109648

Tenaglia AH, Luján LA, Ríos DN, et al. Antibodies to variable surface antigens induce antigenic variation in the intestinal parasite Giardia lamblia. Nat Commun. 2023;14(1):2537. Published 2023 May 3. doi:10.1038/s41467-023-38317-8

Venken K, Jarlborg M, Decruy T, et al. Distinct immune modulatory roles of regulatory T cells in gut versus joint inflammation in TNF-driven spondyloarthritis. Ann Rheum Dis. 2023;82(8):1076-1090. doi:10.1136/ard-2022-223757

Venken K, Decruy T, Sparwasser T, Elewaut D. Tregs protect against invariant NKT cell-mediated autoimmune colitis and hepatitis. Immunology. 2024;171(2):277-285. doi:10.1111/imm.13718

 

2022

Minarrieta, L., G. J. Godoy, L. N. Velazquez, P. Ghorbani, T. Sparwasser and L. Berod. 2022. Regulation of DC metabolism by nitric oxide in murine GM-CSF cultures. Eur J Immunol: e2149691. Lutz MB, Ali S, Audiger C, Autenrieth SE, Berod L, Bigley V, Cyran L, Dalod M, Dörrie J, Dudziak D, Flórez-Grau G, Giusiano L, Godoy GJ, Heuer M, Krug AB, Lehmann CHK, Mayer CT, Naik SH, Scheu S, Schreibelt G, Segura E, Seré K, Sparwasser T, Tel J, Xu H, Zenke M. 2022. Guidelines for mouse and human DC generation. Eur J Immunol. 

Clausen BE, Amon L, Backer RA, Berod L, Bopp T, Brand A, Burgdorf S, Chen L, Da M, Distler U, Dress RJ, Dudziak D, Dutertre CA, Eich C, Gabele A, Geiger M, Ginhoux F, Giusiano L, Godoy GJ, Hamouda AEI, Hatscher L, Heger L, Heidkamp GF, Hernandez LC, Jacobi L, Kaszubowski T, Kong WT, Lehmann CHK, López-López T, Mahnke K, Nitsche D, Renkawitz J, Reza RA, Sáez PJ, Schlautmann L, Schmitt MT, Seichter A, Sielaff M, Sparwasser T, Stoitzner P, Tchitashvili G, Tenzer S, Tochoedo NR, Vurnek D, Zink F, Hieronymus T. 2022. Guidelines for mouse and human DC functional assays. Eur J Immunol. 

von Hoven, G., M. Meyenburg, C. Neukirch, D. Siedenschnur and M. Husmann. 2022. Glutamine 666 renders murine ADAM10 an inefficient S. aureus a-toxin receptor. BioRxiv doi: 10.1101/2022.05.11.491455.

Damasceno, L.E.A., G.C.M. Cebinelli, M.F. Fernandes, D.C. Nascimento, G.A. Publio, M.A.R. Vinolo, S.C. Oliveira, T. Sparwasser, T.M. Cunha, F.Q. Cunha, and J.C. Alves-Filho. 2022. STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program. Cell Rep 39:110838.

Kreft, A., Dennebaum M.S.. 2022. Strongyloides-stercoralis-Infection. Pathologe

Rampoldi, F., E. Donato, L. Ullrich, M. Deseke, A. Janssen, A. Demera, I. Sandrock, A. Bubke, A.L. Juergens, M. Swallow, T. Sparwasser, C. Falk, L. Tan, A. Trumpp, and I. Prinz. 2022. gammadelta T cells license immature B cells to produce a broad range of polyreactive antibodies. Cell Rep 39:110854.

Kremer WM, Gairing SJ, Kaps L, Ismail E, Kalampoka V, Hilscher M, Michel M, Siegel E, Schattenberg JM, Galle PR, Sprinzl MF, Wörns MA, Nagel M, Labenz C. 2022. Characteristics of bacterial infections and prevalence of multidrug-resistant bacteria in hospitalized patients with liver cirrhosis in Germany. Ann Hepatol. Sep-Oct;27(5):100719.

Elrod J, Yarmal F, Mohr C, Dennebaum M, Boettcher M, Vincent D, Reinshagen K, Koenigs I. 2022 Are We Hitting the Target?: The Effectiveness of Distinct Antibiotic Regimens in Pediatric Appendectomies. Pediatr Infect Dis J. Jun 1;41(6):460-465.

Manzke J, Stauf R, Neumann B, Molitor E, Hischebeth G, Simon M, Jantsch J, Rödel J, Becker SL, Halfmann A, Wichelhaus TA, Hogardt M, Serr A, Hess C, Wendel AF, Siegel E, Rohde H, Zimmermann S, Steinmann J. 2022. German Multicenter Study Analyzing Antimicrobial Activity of Ceftazidime-Avibactam of Clinical Meropenem-Resistant Pseudomonas aeruginosa Isolates Using a Commercially Available Broth Microdilution Assay. Antibiotics (Basel). Apr 19;11(5):545.

Wild J, Siegrist B, Hobohm L, Münzel T, Schwanz T, Sagoschen I. 2022. Short and Concise Peer-to-Peer Teaching-Example of a Successful Antibiotic Stewardship Intervention to Increase Iv to Po Conversion. Antibiotics (Basel). Mar 17;11(3):402.

 

2021

Almeida, L., A. Dhillon-LaBrooy, G. Carriche, L. Berod, and T. Sparwasser. 2021. CD4(+) T-cell differentiation and function: Unifying glycolysis, fatty acid oxidation, polyamines NAD mitochondria. J Allergy Clin Immunol 148(1):16-32.

Almeida, L., A. Dhillon-LaBrooy, C.N. Castro, N. Adossa, G.M. Carriche, M. Guderian, S. Lippens, S. Dennerlein, C. Hesse, B.N. Lambrecht, L. Berod, L. Schauser, B.R. Blazar, M. Kalesse, R. Muller, L.F. Moita, and T. Sparwasser. 2021. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis. Immunity 54:68-83 e66.

Carriche, G.M., L. Almeida, P. Stuve, L. Velasquez, A. Dhillon-LaBrooy, U. Roy, M. Lindenberg, T. Strowig, C. Plaza-Sirvent, I. Schmitz, M. Lochner, A.K. Simon, and T. Sparwasser. 2021. Regulating T-cell differentiation through the polyamine spermidine. J Allergy Clin Immunol 147:335-348 e311.

Haack, S., S. Baiker, J. Schlegel, M. Sauer, T. Sparwasser, D. Langenhorst, and N. Beyersdorf. 2021. Superagonistic CD28 stimulation induces IFN-gamma release from mouse T helper 1 cells in vitro and in vivo. Eur J Immunol 51:738-741.

Herold Stephanie, Klodt Tristan, Toelle Daniela, Dennebaum Martin, Lippe Elena, Walz Cleo, Kaes Joachim, Kreft Andreas, Siegel Ekkehard, Munder Markus, Teschner Daniel. Lethal systemic and brain infection caused by Prototheca zopfii algae in a patient with acute myeloid leukemia. Medical Mycology Case Reports 32: 17-20.

Knoll, R.L., and M.S. Dennebaum. 2021. [Fever in pediatric returning travellers]. Monatsschr Kinderheilkd 1-6.

Korkmaz, Y., B. Puladi, K. Galler, P.W. Kammerer, A. Schroder, L. Golz, T. Sparwasser, W. Bloch, A. Friebe, and J. Deschner. 2021. Inflammation in the Human Periodontium Induces Downregulation of the alpha1- and beta1-Subunits of the sGC in Cementoclasts. Int J Mol Sci 22:

Langenwalder, D.B., S. Schmidt, U. Gilli, N. Pantchev, M. Ganter, C. Silaghi, M.L. Aardema, and F.D. von Loewenich. 2021. Corrigendum to "Genetic characterization of Anaplasma phagocytophilum strains from goats (Capra aegagrus hircus) and water buffalo (Bubalus bubalis) by 16S rRNA gene, ankA gene and multilocus sequence typing" [Ticks Tick Borne Dis. 10 (2019) 101267]. Ticks Tick Borne Dis 12:101640.

Lindenberg, M., L. Almeida, A. Dhillon-LaBrooy, E. Siegel, B. Henriques-Normark, and T. Sparwasser. 2021. Clarithromycin impairs tissue-resident memory and Th17 responses to macrolide-resistant Streptococcus pneumoniae infections. J Mol Med (Berl)

Minarrieta, L., L.N. Velasquez, T. Sparwasser, and L. Berod. 2021. Dendritic cell metabolism: moving beyond in vitro-culture-generated paradigms. Curr Opin Biotechnol 68:202-212.

Muller, B.J., A. Westheider, K. Birkner, B. Seelig, S. Kirschnek, C. Bogdan, and F.D. von Loewenich. 2021. Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils. Front Cell Infect Microbiol 11:627630.

Schwanz, T. 2021. [Erregerlexikon: Acinetobacter]. Krankenhaushygiene up2date 16(03):315-334.

Walter I, Adam S, Gentilini MV, Kany AM, Brengel C, Thomann A, Sparwasser T, Köhnke J, Hartmann RW. 2021. Structure-Activity Relationship and Mode-Of-Action Studies Highlight 1-(4-Biphenylylmethyl)-1H-imidazole-Derived Small Molecules as Potent CYP121 Inhibitors. ChemMedChem. 2021 Sep 16;16(18):2786-2801.

Watts D, Janßen M, Jaykar M, Palmucci F, Weigelt M, Petzold C, Hommel A, Sparwasser T, Bonifacio E, Kretschmer K. 2021. Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice. Front Immunol. 2021 Aug 10;12:720133.

 

2020

Besemer, A.S., J. Maus, M.D.A. Ax, A. Stein, S. Vo, C. Freese, K. Nalbach, C. von Hilchen, I.F. Pfalzgraf, I. Koziollek-Drechsler, B. Silva, H. Huesmann, F. Boukhallouk, L. Florin, A. Kern, C. Behl, and A.M. Clement. 2020. Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis. Cell Mol Life Sci

Einwachter, H., A. Heiseke, A. Schlitzer, G. Gasteiger, H. Adler, D. Voehringer, M.G. Manz, Z. Ruzsics, L. Dolken, U.H. Koszinowski, T. Sparwasser, W. Reindl, and S. Jordan. 2020. The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment. Front Immunol 11:1627.

Gamrekelashvili, J., T. Kapanadze, S. Sablotny, C. Ratiu, K. Dastagir, M. Lochner, S. Karbach, P. Wenzel, A. Sitnow, S. Fleig, T. Sparwasser, U. Kalinke, B. Holzmann, H. Haller, and F.P. Limbourg. 2020. Notch and TLR signaling coordinate monocyte cell fate and inflammation. Elife 9:

Hage Andre, Hasenburg Annette, Pietsch Michael, Heimes Anne-Sophie. 2020. MRSA and MRGN in Gynecology Retrospective Analysis of the Exposure Prevalence of MRSA and MRGN taking into account the Risk Factors queried using the Screening Form. Geburtshilfe und Frauenheilkunde 80 (07): 675-678.

Heinrich, S., V. Tripke, T. Huber, E. Siegel, M. Dennebaum, L. Staib, M.A. Worns, K. Oberholzer, J. Mittler, and H. Lang. 2020. [Results of multimodal treatment of hepatic echinococcosis]. Chirurg

Huber, T., A. Serr, W. Geissdorfer, C. Hess, C. Lynker-Assmus, F.D. von Loewenich, C. Bogdan, and J. Held. 2020. Evaluation of the Amplex eazyplex Loop-Mediated Isothermal Amplification Assay for Rapid Diagnosis of Pneumocystis jirovecii Pneumonia. J Clin Microbiol 58:

Knoll, R.L., J. Klopp, G. Bonewitz, B. Grondahl, K. Hilbert, W. Kohnen, K. Weise, B. Plachter, W. Hitzler, F. Kowalzik, S. Runkel, F. Zepp, J. Winter, M.L. Cacicedo, and S. Gehring. 2020. Containment of a Large SARS-CoV-2 Outbreak Among Healthcare Workers in a Pediatric Intensive Care Unit. Pediatr Infect Dis J 39:e336-e339.

Langenwalder, D.B., S. Schmidt, C. Silaghi, J. Skuballa, N. Pantchev, I.A. Matei, A.D. Mihalca, U. Gilli, J. Zajkowska, M. Ganter, T. Hoffman, E. Salaneck, M. Petrovec, and F.D. von Loewenich. 2020. The absence of the drhm gene is not a marker for human-pathogenicity in European Anaplasma phagocytophilum strains. Parasit Vectors 13:238.

Langenwalder, D.B., C. Silaghi, M. Nieder, M. Pfeffer, and F.D. von Loewenich. 2020. Co-infection, reinfection and superinfection with Anaplasma phagocytophilum strains in a cattle herd based on ankA gene and multilocus sequence typing. Parasit Vectors 13:157.

Mamareli, P., F. Kruse, C.W. Lu, M. Guderian, S. Floess, K. Rox, D.S.J. Allan, J.R. Carlyle, M. Bronstrup, R. Muller, L. Berod, T. Sparwasser, and M. Lochner. 2020. Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection. Mucosal Immunol

Mesquita, I., C. Ferreira, D. Moreira, G.E.G. Kluck, A.M. Barbosa, E. Torrado, R.J. Dinis-Oliveira, L.G. Goncalves, C.J. Beauparlant, A. Droit, L. Berod, T. Sparwasser, N. Bodhale, B. Saha, F. Rodrigues, C. Cunha, A. Carvalho, A.G. Castro, J. Estaquier, and R. Silvestre. 2020. The Absence of HIF-1alpha Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. Cell Rep 30:4052-4064 e4057.

Miyanaga, N., H. Takagi, T. Uto, T. Fukaya, J. Nasu, T. Fukui, Y. Nishikawa, T. Sparwasser, N. Choijookhuu, Y. Hishikawa, T. Nakamura, T. Tono, and K. Sato. 2020. Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy. Commun Biol 3:742.

Moyé, S., T. Bormann, R. Maus, T. Sparwasser, I. Sandrock, I. Prinz, G. Warnecke, T. Welte, J. Gauldie, M. Kolb, and U. A. Maus. 2020. Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice. Journal of immunology (Baltimore, Md. : 1950), 204(9), 2429–2438.

Mukhacheva, T.A., D.R. Shaikhova, S.Y. Kovalev, and F.D. von Loewenich. 2020. Phylogeographical diversity of Anaplasma phagocytophilum in the Asian part of Russia based on multilocus sequence typing and analysis of the ankA gene. Infect Genet Evol 80:104234.

Sacramento, L.A., L. Benevides, S.R. Maruyama, L. Tavares, K.F. Fukutani, M. Francozo, T. Sparwasser, F.Q. Cunha, R.P. Almeida, J.S. da Silva, and V. Carregaro. 2020. TLR4 abrogates the Th1 immune response through IRF1 and IFN-beta to prevent immunopathology during L. infantum infection. PLoS Pathog 16:e1008435.

Schaupp, L., S. Muth, L. Rogell, M. Kofoed-Branzk, F. Melchior, S. Lienenklaus, S.C. Ganal-Vonarburg, M. Klein, F. Guendel, T. Hain, K. Schutze, U. Grundmann, V. Schmitt, M. Dorsch, J. Spanier, P.K. Larsen, T. Schwanz, S. Jackel, C. Reinhardt, T. Bopp, S. Danckwardt, K. Mahnke, G.A. Heinz, M.F. Mashreghi, P. Durek, U. Kalinke, O. Kretz, T.B. Huber, S. Weiss, C. Wilhelm, A.J. Macpherson, H. Schild, A. Diefenbach, and H.C. Probst. 2020. Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Cell 181:1080-1096 e1019.

Witkowski, M., M. Witkowski, M. Saffarzadeh, J. Friebel, T. Tabaraie, L. Ta Bao, A. Chakraborty, A. Dorner, B. Stratmann, D. Tschoepe, S.J. Winter, A. Krueger, W. Ruf, U. Landmesser, and U. Rauch. 2020. Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes. Cardiovasc Diabetol 19:20.

 

2019

Ahmetlic, F., T. Riedel, N. Homberg, V. Bauer, N. Trautwein, A. Geishauser, T. Sparwasser, S. Stevanovic, M. Rocken, and R. Mocikat. 2019. Regulatory T Cells in an Endogenous Mouse Lymphoma Recognize Specific Antigen Peptides and Contribute to Immune Escape. Cancer Immunol Res 7:600-608.

Almeida, L., A. Dhillon-LaBrooy, C.N. Castro, N. Ayele, J. Bartel, G.M. Carriche, M. Guderian, S. Lippens, S. Dennerlein, C. Hesse, B.N. Lambrecht, L. Schauser, B.R. Blazar, M. Kalesse, R. Müller, L.F. Moita and T.Sparwasser. 2019. Ribosome-targeting antibiotics impair T cell effector function and ameliorate autoimmunity by blocking mitochondrial protein synthesis. BioRxiv 832956.

Al Nabhani, Z., S. Dulauroy, R. Marques, C. Cousu, S. Al Bounny, F. Dejardin, T. Sparwasser, M. Berard, N. Cerf-Bensussan, and G. Eberl. 2019. A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult. Immunity 50:1276-1288 e1275.

Andersen, L., A.F. Gulich, M. Alteneder, T. Preglej, M.J. Orola, N. Dhele, V. Stolz, A. Schebesta, P. Hamminger, A. Hladik, S. Floess, T. Krausgruber, T. Faux, S.B.A. Andrabi, J. Huehn, S. Knapp, T. Sparwasser, C. Bock, A. Laiho, L.L. Elo, O. Rasool, R. Lahesmaa, S. Sakaguchi, and W. Ellmeier. 2019. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3(+) Regulatory T Cells. Cell Rep 29:4447-4459 e4446.

Gronke, K., P.P. Hernandez, J. Zimmermann, C.S.N. Klose, M. Kofoed-Branzk, F. Guendel, M. Witkowski, C. Tizian, L. Amann, F. Schumacher, H. Glatt, A. Triantafyllopoulou, and A. Diefenbach. 2019. Interleukin-22 protects intestinal stem cells against genotoxic stress. Nature 566:249-253.

Ichikawa, T., K. Hirahara, K. Kokubo, M. Kiuchi, A. Aoki, Y. Morimoto, J. Kumagai, A. Onodera, N. Mato, D.J. Tumes, Y. Goto, K. Hagiwara, Y. Inagaki, T. Sparwasser, K. Tobe, and T. Nakayama. 2019. CD103(hi) Treg cells constrain lung fibrosis induced by CD103(lo) tissue-resident pathogenic CD4 T cells. Nat Immunol 20:1469-1480.

Langenwalder, D.B., S. Schmidt, U. Gilli, N. Pantchev, M. Ganter, C. Silaghi, M.L. Aardema, and F.D. von Loewenich. 2019. Genetic characterization of Anaplasma phagocytophilum strains from goats (Capra aegagrus hircus) and water buffalo (Bubalus bubalis) by 16S rRNA gene, ankA gene and multilocus sequence typing. Ticks Tick Borne Dis 10:101267.

Mamareli, P., F. Kruse, C. Friedrich, N. Smit, T. Strowig, T. Sparwasser, and M. Lochner. 2019. Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile. Eur J Immunol 49:747-757.

Menzer, C., A.M. Menzies, M.S. Carlino, I. Reijers, E.J. Groen, T. Eigentler, J.W.B. de Groot, A.A.M. van der Veldt, D.B. Johnson, F. Meiss, M. Schlaak, B. Schilling, H.M. Westgeest, R. Gutzmer, C. Pfohler, F. Meier, L. Zimmer, K.P.M. Suijkerbuijk, T. Haalck, K.M. Thoms, K. Herbschleb, J. Leichsenring, A. Menzer, A. Kopp-Schneider, G.V. Long, R. Kefford, A. Enk, C.U. Blank, and J.C. Hassel. 2019. Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations. J Clin Oncol 37:3142-3151. 

Mikulicic, S., J. Finke, F. Boukhallouk, E. Wustenhagen, D. Sons, Y. Homsi, K. Reiss, T. Lang, and L. Florin. 2019. ADAM17-dependent signaling is required for oncogenic human papillomavirus entry platform assembly. Elife 8:

Rosch, R.M., K. Buschmann, L. Brendel, T. Schwanz, and C.F. Vahl. 2019. Lactococcus garvieae Endocarditis in a Prosthetic Aortic Valve: A Case Report and Literature Review. J Investig Med High Impact Case Rep 7:2324709619832052.

Schmeh, I., A. Kidszun, A. Welk, T. Schwanz, B. Jansen, and E. Mildenberger. 2019. Evaluation of microbiological screening in a neonatal intensive care unit to optimize empiric antibiotic use. J Hosp Infect 101:362-364.

Schmidleithner, L., Y. Thabet, E. Schonfeld, M. Kohne, D. Sommer, Z. Abdullah, T. Sadlon, C. Osei-Sarpong, K. Subbaramaiah, F. Copperi, K. Haendler, T. Varga, O. Schanz, S. Bourry, K. Bassler, W. Krebs, A.E. Peters, A.K. Baumgart, M. Schneeweiss, K. Klee, S.V. Schmidt, S. Nussing, J. Sander, N. Ohkura, A. Waha, T. Sparwasser, F.T. Wunderlich, I. Forster, T. Ulas, H. Weighardt, S. Sakaguchi, A. Pfeifer, M. Bluher, A.J. Dannenberg, N. Ferreiros, L.J. Muglia, C. Wickenhauser, S.C. Barry, J.L. Schultze, and M. Beyer. 2019. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity 50:1232-1248 e1214.

Serradell, M.C., L.L. Rupil, R.A. Martino, C.G. Prucca, P.G. Carranza, A. Saura, E.A. Fernandez, P.R. Gargantini, A.H. Tenaglia, J.P. Petiti, R.R. Tonelli, N. Reinoso-Vizcaino, J. Echenique, L. Berod, E. Piaggio, B. Bellier, T. Sparwasser, D. Klatzmann, and H.D. Lujan. 2019. Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins. Nat Commun 10:361.

Siemer, S., D. Westmeier, M. Barz, J. Eckrich, D. Wunsch, C. Seckert, C. Thyssen, O. Schilling, M. Hasenberg, C. Pang, D. Docter, S.K. Knauer, R.H. Stauber, and S. Strieth. 2019. Biomolecule-corona formation confers resistance of bacteria to nanoparticle-induced killing: Implications for the design of improved nanoantibiotics. Biomaterials 192:551-559.

Solmaz, G., F. Puttur, M. Francozo, M. Lindenberg, M. Guderian, M. Swallow, V. Duhan, V. Khairnar, U. Kalinke, B. Ludewig, B.E. Clausen, H. Wagner, K.S. Lang, and T.D. Sparwasser. 2019. TLR7 Controls VSV Replication in CD169(+) SCS Macrophages and Associated Viral Neuroinvasion. Front Immunol 10:466.

Tegtmeyer, P., M. Ganter, and F.D. von Loewenich. 2019. Simultaneous infection of cattle with different Anaplasma phagocytophilum variants. Ticks Tick Borne Dis 10:1051-1056.

von Hoven, G., and M. Husmann. 2019. Staphylococcus aureus alpha-Toxin's Close Contacts Ensure the Kill. Trends Microbiol 27:89-90.

von Hoven, G., Q. Qin, C. Neukirch, M. Husmann, and N. Hellmann. 2019. Staphylococcus aureus alpha-toxin: small pore, large consequences. Biol Chem 400:1261-1276.

von Hoven, G., A.J. Rivas, and M. Husmann. 2019. Phobalysin: Fisheye View of Membrane Perforation, Repair, Chemotaxis and Adhesion. Toxins (Basel) 11:

von Loewenich, F.D., C. Seckert, E. Dauber, M.J.L. Kik, A. de Vries, H. Sprong, K. Buschmann, M.L. Aardema, and M. Brandstetter. 2019. Prosthetic Valve Endocarditis with Bartonella washoensis in a Human European Patient and Its Detection in Red Squirrels (Sciurus vulgaris). J Clin Microbiol 58:

Wang, Y., K. Dembowsky, E. Chevalier, P. Stuve, M. Korf-Klingebiel, M. Lochner, L.C. Napp, H. Frank, E. Brinkmann, A. Kanwischer, J. Bauersachs, M. Gyongyosi, T. Sparwasser, and K.C. Wollert. 2019. C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function. Circulation 139:1798-1812.

 

2018

Adomavicius, D., M. Bock, C.F. Vahl, and E. Siegel. 2018. Aerococcus urinae Mitral Valve Endocarditis-Related Stroke: A Case Report and Literature Review. J Investig Med High Impact Case Rep 6:2324709618758351.

Almeida, F.F., S. Tognarelli, A. Marcais, A.J. Kueh, M.E. Friede, Y. Liao, S.N. Willis, K. Luong, F. Faure, F.E. Mercier, J. Galluso, M. Firth, E. Narni-Mancinelli, B. Rais, D.T. Scadden, F. Spallotta, S. Weil, A. Giannattasio, F. Kalensee, T. Zoller, N.D. Huntington, U. Schleicher, A.G. Chiocchetti, S. Ugolini, M.J. Herold, W. Shi, J. Koch, A. Steinle, E. Vivier, T. Walzer, G.T. Belz, and E. Ullrich. 2018. A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets. Oncoimmunology 7:e1475875.

Beger, B., F. von Loewenich, E. Goetze, M. Moergel, and C. Walter. 2018. Leech related Aeromonas veronii complex infection after reconstruction with a microvascular forearm flap. J Maxillofac Oral Surg 17:68-70.

Beilenhoff, U., H. Biering, R. Blum, J. Brljak, M. Cimbro, J.M. Dumonceau, C. Hassan, M. Jung, B. Kampf, C. Neumann, M.Pietsch, L. Pineau, T. Ponchon, S. Rejchrt, J.F. Rey, V. Schmidt, J. Tillett, and J.E. van Hooft. 2018. Reprocessing of flexible endoscopes and endoscopic accessories used in gastrointestinal endoscopy: Position Statement of the European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology Nurses and Associates (ESGENA) - Update 2018. Endoscopy 50:1205-1234.

Byrd, T.T., K. Fousek, A. Pignata, C. Szot, H. Samaha, S. Seaman, L. Dobrolecki, V.S. Salsman, H.Z. Oo, K. Bielamowicz, D. Landi, N. Rainusso, J. Hicks, S. Powell, M.L. Baker, W.S. Wels, J. Koch, P.H. Sorensen, B. Deneen, M.J. Ellis, M.T. Lewis, M. Hegde, B.S. Fletcher, B. St Croix, and N. Ahmed. 2018. TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer. Cancer Res 78:489-500.

Divakaruni, A.S., W.Y. Hsieh, L. Minarrieta, T.N. Duong, K.K.O. Kim, B.R. Desousa, A.Y. Andreyev, C.E. Bowman, K. Caradonna, B.P. Dranka, D.A. Ferrick, M. Liesa, L. Stiles, G.W. Rogers, D. Braas, T.P. Ciaraldi, M.J. Wolfgang, T. Sparwasser, L. Berod, S.J. Bensinger, and A.N. Murphy. 2018. Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. Cell Metab 28:490-503 e497.

Doring, T., L. Zeyen, C. Bartusch, and R. Prange. 2018. Hepatitis B Virus Subverts the Autophagy Elongation Complex Atg5-12/16L1 and Does Not Require Atg8/LC3 Lipidation for Viral Maturation. J Virol 92:

Florin, L., and T. Lang. 2018. Tetraspanin Assemblies in Virus Infection. Front Immunol 9:1140.

Hacker, B., C. Schultheiss, M. Doring, and U. Kurzik-Dumke. 2018. Molecular partners of hNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, suggest its involvement in distinct cellular processes relevant to congenital disorders of glycosylation, cancer, neurodegeneration and a variety of further pathologies. Hum Mol Genet 27:1858-1878.

Hacker, B., C. Schultheiss, and U. Kurzik-Dumke. 2018. Sequential cleavage of the proteins encoded by HNOT/ALG3, the human counterpart of the Drosophila NOT and yeast ALG3 gene, results in products acting in distinct cellular compartments. Hum Mol Genet 27:4231-4248.

Hartmann, J., R.C. Munch, R.T. Freiling, I.C. Schneider, B. Dreier, W. Samukange, J. Koch, M.A. Seeger, A. Pluckthun, and C.J. Buchholz. 2018. A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors. Mol Ther Methods Clin Dev 10:128-143.

Hernandez, P., K. Gronke, and A. Diefenbach. 2018. A catch-22: Interleukin-22 and cancer. Eur J Immunol 48:15-31.

Herrtwich, L., I. Nanda, K. Evangelou, T. Nikolova, V. Horn, Sagar, D. Erny, J. Stefanowski, L. Rogell, C. Klein, K. Gharun, M. Follo, M. Seidl, B. Kremer, N. Munke, J. Senges, M. Fliegauf, T. Aschman, D. Pfeifer, S. Sarrazin, M.H. Sieweke, D. Wagner, C. Dierks, T. Haaf, T. Ness, M.M. Zaiss, R.E. Voll, S.D. Deshmukh, M. Prinz, T. Goldmann, C. Holscher, A.E. Hauser, A.J. Lopez-Contreras, D. Grun, V. Gorgoulis, A. Diefenbach, P. Henneke, and A. Triantafyllopoulou. 2018. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell 174:1325-1326.

Kerz, T., F.D. von Loewenich, J. Roberts, A. Neulen, and F. Ringel. 2018. Cerebrospinal fluid penetration of very high-dose meropenem: a case report. Ann Clin Microbiol Antimicrob 17:47.

Kramer, J., K. Triantafyllias, W. Kohnen, M. Leber, U. Dederichs-Masius, A. Zucker, J. Korber, and A. Schwarting. 2018. Patients with Rheumatic Diseases do not have an Increased Risk of MRSA Carrier Status. Rheumatol Ther 5:371-381.

Memmer, S., S. Weil, and J. Koch. 2018. Reconstitution of a ligand-binding competent murine NKp30 receptor. Immunogenetics 70:185-194.

Schwanz, T., E. Komini, M. Dettenkofer. 2018. Infektionspräventives Vorgehen bei Nachweis von MRGN im Kindesalter. Kinderärztliche Praxis 89:321-335.

Takemura, N., Y. Kurashima, Y. Mori, K. Okada, T. Ogino, H. Osawa, H. Matsuno, L. Aayam, S. Kaneto, E.J. Park, S. Sato, K. Matsunaga, Y. Tamura, Y. Ouchi, Y. Kumagai, D. Kobayashi, Y. Suzuki, Y. Yoshioka, J. Nishimura, M. Mori, K.J. Ishii, M.E. Rothenberg, H. Kiyono, S. Akira, and S. Uematsu. 2018. Eosinophil depletion suppresses radiation-induced small intestinal fibrosis. Sci Transl Med 10:

von Hoven, G., C. Neukirch, M. Meyenburg, S. Schmidt, A. Vences, C.R. Osorio, M. Husmann, and A.J. Rivas. 2018. Cytotoxin- and Chemotaxis-Genes Cooperate to Promote Adhesion of Photobacterium damselae subsp. damselae. Front Microbiol 9:2996.

Wanke, F., Y. Tang, K. Gronke, S. Klebow, S. Moos, J. Hauptmann, A. Shanmugavadivu, T. Regen, I.A. Mufazalov, L.A. Gabriel, S. Reissig, A. Diefenbach, F.C. Kurschus, and A. Waisman. 2018. Expression of IL-17F is associated with non-pathogenic Th17 cells. J Mol Med (Berl) 96:819-829.

Weiss, E., D. Hanzelmann, B. Fehlhaber, A. Klos, F.D. von Loewenich, J. Liese, A. Peschel, and D. Kretschmer. 2018. Formyl-peptide receptor 2 governs leukocyte influx in local Staphylococcus aureus infections. FASEB J 32:26-36.

Welk, A., M. Herrnberger, V. Engel, M. Dennebaum, C. O. von Sochaczewski, and S. Gehring. 2018. Antimicrobial Chemotherapy has a Linear Relationship to the Proportion of Gram-Negative Isolates from Pediatric Burn Wounds. Antibakterielle Therapie thermisch verletzter Kinder begünstigt die Selektion Gram-negativer Keime. Klinische Padiatrie, 230(1), 39–43.

Witkowski, M., M. Witkowski, N. Gagliani, and S. Huber. 2018. Recipe for IBD: can we use food to control inflammatory bowel disease? Semin Immunopathol 40:145-156.

Wu, Z.Y., S.P. Ho, J.F. Cheng, K.C. Tung, Y.K. Hong, S.Y. Chen, A. Menzer, Y.J. Chen, Y.T. Huang, and P.Y. Liu. 2018. Whole-genome characterization of Shewanella algae strain SYT3 isolated from seawater reveals insight into hemolysis. Future Microbiol 13:1709-1717.

Wustenhagen, E., F. Boukhallouk, I. Negwer, K. Rajalingam, F. Stubenrauch, and L. Florin. 2018. The Myb-related protein MYPOP is a novel intrinsic host restriction factor of oncogenic human papillomaviruses. Oncogene 37:6275-6284.