Visual Universitätsmedizin Mainz

PD Dr. med. Arnulf Mayer

PD Dr. med. Mayer
PD Dr. med. Arnulf Mayer

Leitung des experimentellen Forschungslabors
Forschungsgruppenleiter
- AG Tumor-Pathophysiologie
Weitere Infos

Publikationsliste

Publikationsliste

Originalarbeiten:

Impactfactor (des Jahres der Publikation)

Erstautorenschaften

 

Mayer A, Zahnreich S, Brieger J, Vaupel P, Schmidberger H.

Downregulation of EGFR in hypoxic, diffusion-limited areas of squamous cell carcinomas of the head and neck.

Br J Cancer. 2016 Nov 22;115(11):1351-1358.

6,176

Mayer A, Vaupel P, Oberholzer K, Ebert M, Dimitrow M, Kreft A, Mueller-Klieser W, Schmidberger H.

Hypoxia-Associated Marker CA IX Does Not Predict the Response of Locally Advanced Rectal Cancers to Neoadjuvant Chemoradiotherapy. Adv Exp Med Biol. 2016;876:195-200.

1,881

Mayer A, Schwanbeck C, Sommer C, Stockinger M, Giese A, Renovanz M, Vaupel P, Schmidberger H.

Adjuvant temozolomide-based chemoradiotherapy versus radiotherapy alone in patients with WHO III astrocytoma: The Mainz experience.

Strahlenther Onkol. 2015 Aug;191(8):665-71.

2,898

Mayer A, Vaupel P, Struss HG, Giese A, Stockinger M, Schmidberger H.

Response to commentary by Champ and Klement: Is a ketogenic diet the solution for the hyperglycemia problem in glioblastoma therapy?

Strahlenther Onkol. 2015 Mar;191(3):283-4.

2,898

Mayer A, Schmidt M, Seeger A, Serras AF, Vaupel P, Schmidberger H.

GLUT-1 expression is largely unrelated to both hypoxia and the Warburg phenotype in squamous cell carcinomas of the vulva.

BMC Cancer. 2014 Oct 12;14:760.

3,362

Mayer A, Vaupel P, Struss HG, Giese A, Stockinger M, Schmidberger H.

Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme.

Strahlenther Onkol. 2014 Oct;190(10):933-8.

2,914

Mayer A, Höckel M, Schlischewsky N, Schmidberger H, Horn LC, Vaupel P.

Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix.

Br J Cancer. 2013 Feb 5;108(2):402-8.

4,817

Mayer A, Schneider F, Vaupel P, Sommer C, Schmidberger H.

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma.

Int J Oncol. 2012 Oct;41(4):1260-70.

2,657

Mayer A, von Wallbrunn A, Vaupel P.

Evidence against a major role for TKTL-1 in hypoxic and normoxic cancer cells.

Adv Exp Med Biol. 2011; 701: 123-8.

 

1,379

Mayer A, Höckel M, Horn LC, Schmidberger H, Vaupel P.

GLUT-1 staining of squamous cell carcinomas of the uterine cervix identifies a novel element of invasion.

Int J Oncol 2011; 38: 145-50.

 

2,571

Mayer A, Von Wallbrunn A, Vaupel P.

Glucose metabolism of malignant cells is not regulated by transketolase-like (TKTL)-1.

Int J Oncol 2010; 37: 265-71.

 

2,447

Mayer A, Höckel M, von Wallbrunn A, Horn LC, Wree A, Vaupel P.

HIF-mediated hypoxic response is missing in severely hypoxic uterine leiomyomas.

Adv Exp Med Biol 2010; 662: 399-405.

 

2,02

Mayer A, Steimel M, Wree A, Kelleher D, Vaupel P.

Solid tumours arising from differently pre-oxygenated cells: comparable growth rates despite dissimilar tissue oxygenation.

Int J Radiat Biol 2009; 85: 981-8.

 

2,178

Mayer A, Höckel M, Wree A, Leo C, Horn LC, Vaupel P.

Lack of hypoxic response in uterine leiomyomas despite severe tissue hypoxia. Cancer Res 2008; 68: 4719-26.

 

7,514

Mayer A, Höckel M, Vaupel P.

Carbonic anhydrase IX expression and tumor oxygenation status do not correlate at the microregional level in locally advanced cancers of the uterine cervix.

Clin Cancer Res 2005; 11: 7220-5.

 

6,488

Mayer A, Höckel M, Wree A, Vaupel P.

Microregional expression of glucose transporter-1 and oxygenation status: lack of correlation in locally advanced cervical cancers.

Clin Cancer Res 2005; 11: 2768-73.

 

6,488

Mayer A, Wree A, Höckel M, Leo C, Pilch H, Vaupel P.

Lack of correlation between expression of HIF-1α protein and oxygenation status in identical tissue areas of squamous cell carcinomas of the uterine cervix.

Cancer Res 2004; 64: 5876-81.

 

7,514

Mayer A, Höckel M, Thews O, Schlenger K, Vaupel P.

Impact of oxygenation status and patient age on DNA content in cancers of the uterine cervix.

Int J Radiat Oncol Biol Phys 2003; 56: 929-36.

4,639

 

 

Letztautorenschaften

 

Schmidberger H, Rapp M, Ebersberger A, Hey-Koch S, Loquai C, Grabbe S, Mayer A.

Long-term survival of patients after ipilimumab and hypofractionated brain radiotherapy for brain metastases of malignant melanoma: sequence matters.

Strahlenther Onkol. 2018 Dec;194(12):1144-1151.

2,459

Metzger JC, Wollschläger D, Miederer M, Vaupel P, Moehler M, Schmidberger H, Mayer A.

Inclusion of PET-CT into planning of primary or neoadjuvant chemoradiotherapy of esophageal cancer improves prognosis.

Strahlenther Onkol. 2017 Oct;193(10):791-799.

2,459

Vaupel P, Mayer A.

Hypoxia-Driven Adenosine Accumulation: A Crucial Microenvironmental Factor Promoting Tumor Progression.

Adv Exp Med Biol. 2016;876:177-183.

1,881

 

 

Ko-Autorenschaften

 

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F.

Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling.

MBio. 2019 Feb 12;10(1). pii: e02323-18.

6,689

Paret C, Russo A, Otto H, Mayer A, Zahnreich S, Wagner W, Samuel D, Scharnhorst D, Solomon DA, Dhall G, Wong K, Bender H, Alt F, Wingerter A, Neu MA, Beck O, Prawitt D, Eder S, Henninger N, El Malki K, Lehmann N, Backes N, Roth L, Seidmann L, Sommer C, Brockmann MA, Staatz G, Schmidberger H, Faber J.

Personalized therapy: CNS HGNET-BCOR responsiveness to arsenic trioxide combined with radiotherapy.

Oncotarget. 2017 Dec 11;8(69):114210-114225.

5,168 (2016)

Holzhäuser E, Berlin M, Wollschläger D, Bezold T, Mayer A, Heß G, Schmidberger H.

Patterns of failure of diffuse large B‑cell lymphoma patients after involved-site radiotherapy.

Strahlenther Onkol. 2017 Dec;193(12):1014-1023.

2,459

Affolter A, Samosny G, Heimes AS, Schneider J, Weichert W, Stenzinger A, Sommer K, Jensen A, Mayer A, Brenner W, Mann WJ, Brieger J.

Multikinase inhibitors sorafenib and sunitinib as radiosensitizers in head and neck cancer cell lines.

Head Neck. 2017 Apr;39(4):623-632.

2,471

Hoppe-Seyler K, Bossler F, Lohrey C, Bulkescher J, Rösl F, Jansen L, Mayer A, Vaupel P, Dürst M, Hoppe-Seyler F.

Induction of dormancy in hypoxic human papillomavirus-positive cancer cells.

Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E990-E998.

9,661 (2016)

Bostel T, Förster R, Schlampp I, Wolf R, Serras AF, Mayer A, Bruckner T, Welzel T, Schmidberger H, Debus J, Rief H.

Stability, prognostic factors and survival of spinal bone metastases in malignant melanoma patients after palliative radiotherapy.

Tumori. 2016 Mar-Apr;102(2):156-61.

1,233

Wree A, Mayer A, Westphal S, Beilfuss A, Canbay A, Schick RR, Gerken G, Vaupel P.

Adipokine Expression in Brown and White Adipocytes in Response to Hypoxia.

J Endocrinol Invest. 2011 Sep 27 [Epub ahead of print]

1,476

Vaupel P, Mayer A, Höckel M.

Oxygenation status of primary and recurrent squamous cell carcinomas of the vulva.

Eur J Gynaecol Oncol 2006; 27: 142-6.

0,641

Vaupel P, Mayer A, Briest S, Höckel M.

Oxygenation gain factor: a novel parameter characterizing the association between hemoglobin level and the oxygenation status of breast cancers.

Cancer Res 2003; 63: 7634-7.

7,514

Vaupel P, Thews O, Mayer A, Höckel S, Höckel M.

Oxygenation status of gynecologic tumors: what is the optimal hemoglobin level? Strahlenther Onkol 2002; 178: 727-31.

3,005

 

 

Übersichtsarbeiten

 

Mayer A, Vaupel P.

Multiparametric Analysis of the Tumor Microenvironment: Hypoxia Markers and Beyond.

Adv Exp Med Biol. 2017;977:101-107.

1,881 (2016)

Vaupel P, Mayer A.

Tumor Oxygenation Status: Facts and Fallacies.

 Adv Exp Med Biol. 2017;977:91-99.

1,881 (2016)

Vaupel P, Mayer A.

Tumor Hypoxia: Causative Mechanisms, Microregional Heterogeneities, and the Role of Tissue-Based Hypoxia Markers.

Adv Exp Med Biol. 2016;923:77-86.

1,881

Vaupel P, Mayer A.

Can respiratory hyperoxia mitigate adenosine-driven suppression of antitumor immunity?

Ann Transl Med. 2015 Nov;3(19):292.

-

Zahnreich S, Mayer A, Loquai C, Grabbe S, Schmidberger H.

Radiotherapy with BRAF inhibitor therapy for melanoma: progress and possibilities.

Future Oncol. 2016 Jan;12(1):95-106.

2,131

Vaupel P, Mayer A.

The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities. Antioxid Redox Signal.

2015 Apr 1;22(10):878-80.

7,093

Vaupel P, Mayer A.

Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications.

Adv Exp Med Biol. 2014;812:19-24.

n/a

1,825 (2013)

Mayer A, Vaupel P.

Hypoxia, lactate accumulation, and acidosis: siblings or accomplices driving tumor progression and resistance to therapy?

Adv Exp Med Biol. 2013;789:203-209.

 1,825

Vaupel P, Mayer A.

Availability, not respiratory capacity governs oxygen consumption of solid tumors. Int J Biochem Cell Biol. 2012 Sep;44(9):1477-81.

4,152

Vaupel P, Höckel M, Mayer A.

Oxygenation status of urogenital tumors.

Adv Exp Med Biol 2011; 701: 123-8.

1,379

Mayer A, Höckel M, Vaupel P.

Endogenous hypoxia markers: case not proven!

Adv Exp Med Biol 2008; 614: 127-36.

 

2,02

Vaupel P, Höckel M, Mayer A.

Detection and characterization of tumor hypoxia using pO2 histography.

Antioxid Redox Signal 2007; 9: 1221-35.

 

6,19

Vaupel P, Mayer A.

Hypoxia in cancer: significance and impact on clinical outcome.

Cancer Metastasis Rev 2007; 26: 225-39.

 

6,766

Mayer A, Höckel M, Vaupel P.

Endogenous hypoxia markers in locally advanced cancers of the uterine cervix: reality or wishful thinking?

Strahlenther Onkol 2006; 182: 501-10.

 

3,005

Vaupel P, Mayer A, Höckel M.

Impact of hemoglobin levels on tumor oxygenation: the higher, the better?

Strahlenther Onkol 2006; 182: 63-71.

 

3,005

Vaupel P, Mayer A.

Hypoxia and anemia: effects on tumor biology and treatment resistance.

Transfus Clin Biol 2005; 12: 5-10.

 

1,016

Vaupel P, Mayer A, Briest S, Höckel M.

Hypoxia in breast cancer: role of blood flow, oxygen diffusion distances, and anemia in the development of oxygen depletion.

Adv Exp Med Biol 2005; 566: 333-42.

 

2,02

Vaupel P, Mayer A, Höckel M.

Tumor hypoxia and malignant progression.

Methods Enzymol 2004; 381: 335-54.

 

2,312

Letter to the Editor

 

Vaupel P, Mayer A. Erythropoietin to treat anaemia in patients with head and neck cancer. Lancet 2004; 363: 992

 

28,409

 

Buchartikel (mit ISBN)

Vaupel P, Mayer A, Höckel M. Relationship between hemoglobin levels and tumor oxygenation. In: Nowrousian, MR, ed., Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology. Scientific and Clinical Aspects of Anemia in Cancer, Springer, 2008, pp. 265-82 (ISBN 978-3-211-25223-9)

Vaupel P, Mayer A. Effects of anaemia and hypoxia on tumour biology. In: Bokemeyer C, Ludwig H, eds., Anaemia in Cancer, 2nd edit, Elsevier, 2005, pp. 47-66. (ISBN 978-0080445755)

Mayer A, Vaupel P. Hypoxia markers and their clinical relevance. In: Osinsky S, Friess H, Vaupel P, eds., Tumor hypoxia in the clinical setting, Akademperiodyka, 2011, pp. 187-202. (ISBN 978-966-360-169-4)

 

Veröffentlichte Vorträge/Postervorträge

Holzhäuser, E., Pfeiffer, S., Mayer, A., and Schmidberger, H. (2018). Spatial patterns of failure following complete tumor resection and adjuvant radiotherapy +/- temozolomide in patients with glioblastoma. Strahlenther Onkol 194, S116-S116.

Mayer, A., Haist, M., Rapp, M., Bankhead, P., Vaupel, P., Loquai, C., Grabbe, S., and Schmidberger, H. (2018). The Extent of Initial Tumor Infiltration By CD8-Positive CTL in Non-CNS Tissue Is Correlated with Survival Following Radiation Therapy and Ipilimumab for Brain Metastases of Malignant Melanoma. Int J Radiat Oncol Biol Phys 102, E164-E165.

Mayer, A., and Schmidberger, H. (2018). Smoking and alcohol consumption during primary (chemo) radiotherapy of tumors of the head and neck region are correlated with a detrimental prognosis. Strahlenther Onkol 194, S75-S75.

Otto, M., Gonciarz, K., Sbalzarini, I. F., Bankhead, P., Brieger, J., Schmidberger, H., and Mayer, A. (2018). Analyzing spatial interactions in multiplex immunofluorescence whole slide tissue specimens of cancers of the head and neck region. Strahlenther Onkol 194, S51-S52.

Vaupel, P., Shi, K., and Mayer, A. (2018). Influence of diffusion limitations of PET Tracers on imaging of tumor hypoxia. Strahlenther Onkol 194, S94-S94.

Zahnreich, S., Brieger, J., Multhoff, G., Vaupel, P., Schmidberger, H., and Mayer, A. (2018). Anoxia induces EGFR downregulation in squamous cell carcinomas of the head and neck. Strahlenther Onkol 194, S75-S76.

Zahnreich, S., Brieger, J., Multhoff, G., Vaupel, P., Schmidberger, H., and Mayer, A. (2017). The tumor microenvironment induces EGFR downregulation in squamous cell carcinomas of the head and neck. Strahlenther Onkol 193, S82-S82.

Schmidberger, H., Rapp, M., Ebersberger, A., Loquai, C., Grabbe, S., and Mayer, A. (2017). Long term survival of patients after Ipilimumab and hypofractionated brain radiotherapy for brain metastases of malignant melanoma: sequence matters. J Dtsch Dermatol Ges 15, 11-11.

Dimitrow, M., Mayer, A., Miederer, M., Hey-Koch, S., Menig, M., Schreckenberger, M., and Schmidberger, H. (2016). Frequent Changing of the radiotherapeutic Concept for the Salvage Therapy of Prostate Carcinoma by PET-CT. Strahlenther Onkol 192, 55-55.

Mayer, A., Brieger, J., Vaupel, P., and Schmidberger, H. (2016). Downregulation of Na+-K+-ATPase under hypoxic conditions: A HIF-independent marker of tumor hypoxia? Strahlenther Onkol 192, 46-46.

Metzger, J. C., Vaupel, P., Mohler, M., Schmidberger, H., and Mayer, A. (2016). Prognostic impact of PET-CT-based planning of primary or neoadjuvant chemoradiotherapy of esophageal cancer. Strahlenther Onkol 192, 20-20.

Mayer, A., Brieger, J., Vaupel, P., Stack, E. C., Wendik, B., Bouche-Zurhove, K., and Schmidberger, H. (2015). Multispectral, multiplexed analysis of the tumor microenvironment in FFPE tissue of head and neck cancer. Strahlenther Onkol 191, S45-S45.

Mayer, A., Schwanbeck, C., Sommer, C., Stockinger, M., Giese, A., Renovanz, M., Vaupel, P., and Schmidberger, H. (2015). Combined chemoradiotherapy with temozolomide versus radiotherapy alone in anaplastic astrocytoma WHO III. Strahlenther Onkol 191, S37-S38.

Mayer, A., Struss, H. G., Schmidberger, H., and Vaupel, P. (2015). Plasma levels of the potent antioxidant uric acid do not influence overall survival of patients following adjuvant chemoradiotherapy for glioblastoma multiforme. Strahlenther Onkol 191, S76-S77.

Vaupel, P., and Mayer, A. (2015). Localized 43 degrees C-hyperthermia aggravates hypoxia-driven adenosine accumulation in rat DS-sarcomas possibly inhibiting anti-tumor immune responses. Strahlenther Onkol 191, S85-S85.

Dimitrow, M. A., Rösler, H. P., Mayer, A., Schmidberger, H., and Karle, H. (2014). Reproducibility and Accuracy of Patient positioning with the System "Catalyst "(C-RAD): Datas from a Pilot study. Strahlenther Onkol 190, 150-150.

Kretzer, T., Vaupel, P., Reinke-Kretzer, C., Schmidberger, H., and Mayer, A. (2014). RADIAS: An HTML-based database for translational research. Strahlenther Onkol 190, 143-143.

Mayer, A., Vaupel, P., Struss, H. G., Giese, A., Stockinger, M., and Schmidberger, H. (2014). Hyperglycemic episodes during adjuvant therapy of glioblastoma are correlated with a significantly poorer prognosis. Strahlenther Onkol 190, 32-32.

Zahnreich, S., Ebersberger, A., Mayer, A., and Schmidberger, H. (2014). gamma-H2AX: A sensitive Biodosimeter in radiotherapy? Strahlenther Onkol 190, 34-35.

Mayer, A., Schwanbeck, C., Vaupel, P., Sommer, C., and Schmidberger, H. (2013). Activation of the HIF-system may identify an aggressive phenotype in anaplastic astrocytoma: data from a pilot study. Strahlenther Onkol 189, 26-27.

Mayer, A., Sommer, C., Schneider, F., Schmidberger, H., and Vaupel, P. (2013). Heterogeneity of critical oxygen diffusion distances in glioblastomas: assessment using GLUT-1 immunohistochemistry. Strahlenther Onkol 189, 128-128.

Reinke-Kretzer, C., Mayer, A., Dimitrow, M., Hampel, C., Heinrich, S., Rösler, H. P., and Schmidberger, H. (2013). Results of 3D-HDR Brachytherapy retroperitoneal Soft tissue sarcomas: preliminary Data of the Mainz Collective. Strahlenther Onkol 189, 109-109.

Mayer, A., Schneider, F., Sommer, C., Vaupel, P., and Schmidberger, H. (2012). Hypoxia leading to HIF-1 dependent gene expression may indicate the transition from anaplastic astrocytoma to glioblastoma multiforme. Strahlenther Onkol 188, 114-115.

Mayer, A., Höckel, M., Horn, L. C., Schmidberger, H., and Vaupel, P. (2011). Evidence against a major role for SDF-1/CXCL-12 signaling in hypoxia-induced invasiveness of cancers of the uterine cervix. Strahlenther Onkol 187, 121-121.

Ebersberger, A., Hey-Koch, S., Mayer, A., Menig, M., and Schmidberger, H. (2010). Hirnfiliae of malignant melanoma: Hypofractionated accelerated vs conventionally fractionated Whole Brain iradiation, a retrospective Analysis. Strahlenther Onkol 186, 140-140.

Mayer, A., Höckel, M., Horn, L. C., and Vaupel, P. (2010). Differential activity of the HIF-system in Ieiomyosarcomas vs. Ieiomyomas is not correlated with markers of cap-dependent, 5'-TOP- or IRES-mediated control of mRNA translation. Strahlenther Onkol 186, 113-113.

Mayer, A., Schneider, F., Vaupel, P., and Schmidberger, H. (2010). Ionizing radiation leads to normoxic stabilization of HIF-1 alpha in a manner partially dependent on PI3 kinase activation in glioblastoma cells. Strahlenther Onkol 186, 114-114.

Menig, M., Oberholzer, K., Hansen, T., Kreft, A., Mayer, A., Duber, C., and Schmidberger, H. (2010). MRI based identification of mucinous adenocarcinoma of the rectum - a novel predictive marker for patients undergoing neoadjuvant radiochemotherapy? Strahlenther Onkol 186, 21-22.

Mayer, A., Höckel, M., Schlischewsky, N., Horn, L. C., and Vaupel, P. (2009). Evidence against hypoxia-induced epithelial-to-mesenchymal transitions in cervical cancer. Strahlenther Onkol 185, 108-109.

Leo, C., Mayer, A., Horn, L. C., Hentschel, B., Vaupel, P., and Höckel, M. (2008). Hypoxia in benign and malignant uterus tumor. Geburtsh Frauenheilk 68, S10-S10.

Methodological aspects of HIF-1α immunohistochemistry in cervical cancers. Mayer A, Wree A [Tumor hypoxia: From Genomics and Proteomics to Malignant Progression and Therapeutics. International Symposium, 10 – 11.10.2003, Akademie der Wissenschaften und der Literatur, Mainz]

Proponenten und Opponenten in der Strahlenbiologie / Radioonkologie: Hypoxie und Ploidiestatus in Zervixkarzinomen (Opponent). Mayer A [8. Jahreskongress der DEGRO, 2002, Berlin]

 

Nicht veröffentlichte Vorträge

Combined Radio- and Immunotherapy: the Role of the Microenvironment. Mayer, A [International Oncology Summit at ESTRO, 20th April 2018, Palau Congressos, Barcelona, Spain]

Exploring the tumor microenvironment using multiparametric IHC. Mayer, A [Presentation at Varian Headquarters in Palo Alto, CA, USA am Freitag, 29.09.2017]

Radio- und Chemotherapie von Wirbelsäulentumoren, Mayer, A [Mainzer Basiskurs der Akademie der DWG gGmbH, Modul 5, 05.-06.04.2018, Erbacher Hof, Mainz]

Strahlentherapie bei urologischen Tumoren – kurative Therapie, trimodale Therapie und Palliation. Mayer, A [OSKAR – 1. Urologischer Weiterbildungszirkel: Multimodales Teaching für Assistenzärzte, 28.02.2018, Klinik für Urologie, Universitätsmedizin Mainz, Veranstalter: Janssen-Cilag GmbH]

Multiparametrische Analyse des Tumormikromilieus. Mayer, A [Fortbildungs der Klinik und Poliklinik für RadioOnkologie und Strahlentherapie der Technischen Universität München Klinikum rechts der Isar am 24.07.2015]

Are HIFs and HIF-dependent downstream proteins specific/valid indicators for tumor hypoxia in the clinical setting? Vaupel P, Mayer A [25th Annual Meeting of the EUROPEAN SOCIETY for HYPERTHERMIC ONCOLOGY, June 4 - 6 , 2009, Verona, Italy]

Uterine leiomyomas are severely hypoxic but do not induce HIF-1α, GLUT-1 or CA IX. Mayer A, Höckel M, Wree A, Horn LC, Vaupel P. [Atmungsphysiologische Arbeitstagung, 2008, Göttingen]

Complete absence of HIF-1α induction in severely hypoxic uterine leiomyomas. Mayer A, Höckel M, Wree A, Horn LC, Vaupel P [87. Jahrestagung der Deutschen Physiologischen Gesellschaft, 02 – 05.03.2008, Köln]

Welche Rolle spielt HIF-1alpha in hypoxischen Zellen in Normalgeweben und benignen Tumoren? Mayer A [Gastvortrag im Interdisziplinären Zentrum für Klinische Forschung (IZKF), Leipzig, 23.07.2008]

No upregulation of hypoxia-inducible PHD-2 and PHD-3 in chronically hypoxic uterine leiomyomas. Mayer A, Höckel M, von Wallbrunn A, Horn LC, Vaupel P [54th Annual Meeting of the Radiation Research Society, 21. – 24. September 2008, Boston, MA, USA]

Regulation of the HIF system in benign vs. malignant uterine tumors: a paradigm shift for the understanding of the hypoxic response? Mayer A, Höckel M, von Wallbrunn A, Horn LC, Vaupel P [54th Annual Meeting of the Radiation Research Society, 21. – 24. September 2008, Boston, MA, USA]

Tumor Pathophysiology: Role of hypoxia in malignant progression. Mayer A, Vaupel P [Tumor hypoxia and malignant progression, International Conference, 1. – 4. October, 2008, Kyiv, Ukraine]

Is development of tumour hypoxia during localized hyperthermia a matter of concern? Kelleher DK, Steimel M, Mayer A, Vaupel P [28. Congress Internat. Clinical Hyperthermia Society, Mumbai (Indien), 2007]

A simple method for the quantification of microcirculation-associated parameters using ImageJ. Mayer A, Vaupel P [Joint Meeting of The German Society of Physiology and The Federation of European Physiological Societies, 26. - 29. März 2006, München]

No correlation between hypoxia-associated markers and oxygenation status in cancers of the uterine cervix. Mayer A, Wree A, Höckel M, Vaupel P [27. Deutscher Krebskongress, 22. - 26. März 2006, Berlin]

No correlation at the microregional level between oxygenation status and expression of HIF-1a, GLUT-1 and CA IX in locally advanced cervix cancers. Mayer A, Wree A, Höckel M, Vaupel P [11. Jahreskongress der DEGRO, 26. – 29.05.2005, Karlsruhe]

 

 

Poster

Mayer, A., Haist, M., Vaupel, P., Schmidberger, H. (2017) Using QuPath to investigate mechanisms of melanoma immune escape in human whole slide tumor sections. 15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, 17.-19. Juni 2017, Wolfsberg Castle Conference Center, Ermatingen, Switzerland

Mayer, A., Brieger, J., Vaupel, P., Schmidberger, H. (2015) Complex relationship between EGFR expression and hypoxia in cancers of the head and neck: A novel “flow-cytometry-in-tissue” approach. 14th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, 20.-22. Juni 2015, Wolfsberg Castle Conference Center, Ermatingen, Switzerland

Mayer, A., Vaupel, P., Schmidt, M., Schmidberger, H. (2013) A novel technique for the study of proliferation in normoxic vs. hypoxic tumor regions. 5th UCT Science Day, 6. September 2013, Universitäres Centrum für Tumorerkrankungen, Frankfurt.

Mayer, A., Vaupel, P., Schmidberger, H. (2013) Multiparametric Immunohistochemistry in Registered Serial Sections (MIRSS): A novel method for the characterization of the tumor microenvironment. 13th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, 22.-24. Juni 2013, Wolfsberg Castle Conference Center, Ermatingen, Switzerland

Mayer, A., Schneider, F., Vaupel, P., Sommer, C., and Schmidberger, H. (2012). The glycolytic phenotype of glioblastoma multiforme is primarily caused by diffusion-limited hypoxia. 12th Biennial Meeting of the DGDR Germany Society for Research on DNA Repair / 15th Annual Meeting of the GBS Gesellschaft für biologische Strahlenforschung, 17-20. September 2012, München.

Solid tumors arising from differently pre-oxygenated cells: Comparable growth rates despite dissimilar tissue oxygenation. Mayer A, Steimel M, Wree A, Kelleher D, Vaupel P [2nd Workshop on Radiation and Multidrug Resistance Mediated via the Tumor Microenvironment, 08. - 10. February 2009, Dresden]

Metabolic adaptation of tumor-initiating cells is a key factor determining angiogenesis in a sarcoma allograft model. Mayer A, Steimel M, Wree A, Kelleher D, Vaupel P [88th Annual Meeting of the German Physiological Society, from Sunday, March 22, to Wednesday, March 25, 2009, Giessen]

Lack of hypoxia-induced down-regulation of E-Cadherin in cervical cancer. Mayer A, Höckel M, Schlischewsky N, Horn LC, Vaupel P [11th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, June 27-29, 2009, Ermatingen, Switzerland]

Allografted sarcoma cell growth results in microenvironments similar to pre-implantation conditions. Mayer A, Steimel M, Wree A, Kelleher D, Vaupel P [55TH Annual Meeting of the Radiation Research Society, October 4-7, 2009, Savannah, Georgia, USA]