Visual Universitätsmedizin Mainz

Dr. rer. nat. Sebastian Zahnreich

Dr. rer. nat. Zahnreich
- Biologische Dosimetrie
+49 (0) 6131 17-2860
+49 (0) 6131 17-9375


Manuela Marron , Lara Kim Brackmann , Heike Schwarz , Willempje Hummel-Bartenschlager , Sebastian Zahnreich , Danuta Galetzka , Iris Schmitt , Christian Grad , Philipp Drees , Johannes Hopf , Johanna Mirsch , Peter Scholz-Kreisel , Peter Kaatsch , Alicia Poplawski , Moritz Hess , Harald Binder , Thomas Hankeln , Maria Blettner , Heinz Schmidberger

Identification of Genetic Predispositions Related to Ionizing Radiation in Primary Human Skin Fibroblasts From Survivors of Childhood and Second Primary Cancer as Well as Cancer-Free Controls: Protocol for the Nested Case-Control Study KiKme

JMIR Res Protoc. 2021 Nov 11;10(11):e32395. doi: 10.2196/32395.

Sebastian Zahnreich , Heinz Schmidberger

 Childhood Cancer: Occurrence, Treatment and Risk of Second Primary Malignancies

Cancers (Basel) Mai 2021

Sebastian Zahnreich, Senayit Gebrekidan, Gabriele Multhoff, Peter Vaupel1, Heinz Schmidberger and Arnulf Mayer

Oxygen Deprivation Modulates EGFR and PD-L1 in Squamous Cell Carcinomas of the Head and Neck

Frontiers in oncology, Februar 2021

S. Zahnreich, H.P. Rösler, C. Schwanbeck, H. Karle, H. Schmidberger,

Radiation-induced DNA double-strand breaks in peripheral leukocytes and therapeutic response of heel spur patients treated by orthovoltage X-rays or a linear accelerator, Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft, (2020).

S. Zahnreich, A. Poplawski, C. Hartel, L.S. Eckhard, D. Galetzka, T. Hankeln, M. Löbrich, M. Marron, J. Mirsch, S. Ritter, P. Scholz-Kreisel, C. Spix, H. Schmidberger,

Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms,

Frontiers in oncology, 10 (2020) 1338.

L.K. Brackmann, A. Poplawski, C.L. Grandt, H. Schwarz, T. Hankeln, S. Rapp, S. Zahnreich, D. Galetzka, I. Schmitt, C. Grad, L. Eckhard, J. Mirsch, M. Blettner, P. Scholz-Kreisel, M. Hess, H. Binder, H. Schmidberger, M. Marron,

Comparison of time and dose dependent gene expression and affected pathways in primary human fibroblasts after exposure to ionizing radiation,

 Molecular medicine (Cambridge, Mass.), 26 (2020) 85.

Paret C, Russo A, Otto H, Mayer A, Zahnreich S, Wagner W, et al.

Personalized therapy: CNS HGNET-BCOR responsiveness to arsenic trioxide combined with radiotherapy.

Oncotarget. 2017;8(69):114210-25.

Zahnreich S, Mayer A, Loquai C, Grabbe S, Schmidberger H.

Radiotherapy with BRAF inhibitor therapy for melanoma: progress and possibilities.

Future oncology (London, England). 2016;12(1):95-106.

Zahnreich S, Ebersberger A, Karle H, Kaina B, Schmidberger H.

Quantification of Radiation Biomarkers in Leukocytes of Breast Cancer Patients Treated with Different Modalities of 3D-CRT or IMRT.

Radiation research. 2016;186(5):508-19.

Mayer A, Zahnreich S, Brieger J, Vaupel P, Schmidberger H.

Downregulation of EGFR in hypoxic, diffusion-limited areas of squamous cell carcinomas of the head and neck.

British journal of cancer. 2016;115(11):1351-8.

Zahnreich S, Ebersberger A, Kaina B, Schmidberger H.

Biodosimetry Based on γ-H2AX Quantification and Cytogenetics after Partial- and Total-Body Irradiation during Fractionated Radiotherapy.

Radiation research. 2015;183(4):432-46.

Dettmering T, Zahnreich S, Colindres-Rojas M, Durante M, Taucher-Scholz G, Fournier C.

Increased effectiveness of carbon ions in the production of reactive oxygen species in normal human fibroblasts.

Journal of radiation research. 2015;56(1):67-76.

Zahnreich S, Krunic D, Melnikova L, Szejka A, Drossel B, Sabatier L, et al.

Duplicated chromosomal fragments stabilize shortened telomeres in normal human IMR-90 cells before transition to senescence.

Journal of cellular physiology. 2012;227(5):1932-40.

Fournier C, Zahnreich S, Kraft D, Friedrich T, Voss KO, Durante M, et al.

The fate of a normal human cell traversed by a single charged particle.

Scientific reports. 2012;2:643.

Zahnreich S, Melnikova L, Winter M, Nasonova E, Durante M, Ritter S, et al.

Radiation-induced premature senescence is associated with specific cytogenetic changes. Mutation research. 2010;701(1):60-6.

Fournier C, Winter M, Zahnreich S, Nasonova E, Melnikova L, Ritter S.

Interrelation amongst differentiation, senescence and genetic instability in long-term cultures of fibroblasts exposed to different radiation qualities.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2007;83(3):277-82.