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Doctoral Candidates

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Najla Abassi

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Marta Agacinska 

Topic: New mechanisms of mCMV immune evasion and its control by cellular factors

TP11 Distler/Lemmermann

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Nawid Albinger

Topic: Generation and Evaluation of AML specific CAR NK cells

TP12 Ullrich/Kühn

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Klajdi Begaj (MD)

Topic: In vitro und in vivo Testungen von Makrophagen-repolarisierender siRNA zur Therapie der Leberfibrose und des HCC

TP08 Schuppan/Deppermann

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Tobias Bexte (MD)

Topic: Entwicklung einer CAR-NK-Zell Therapie gegen Leukämie

TP12 Ullrich/Kühn

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Nabil Boui

Speaker of the IRTG doctoral candidates

Topic: Deciphering the role of cAMP response element driven gene regulation in tumor-associated macrophage polarization and function

TP01 Bopp

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Kathrin Braband

Speaker of the IRTG doctoral candidates

Topic: Single cell analysis of the immune landscape in human cancer with a focus on the role of tissue-resident regulatory T cells in cancer development and progression

TP19N Delacher/Marini

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Helena Maria Brüning (MD)

Topic: The role of protein kinase CK2 in dendritic cells in anti tumor immunity

TP01 Bopp

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Leon Buchinger (MD)

Topic: NK-Zelltherapie von malignen hämatologischen Erkrankungen

TP12 Ullrich/Kühn

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Julia Campe

Topic: The role of CD4 T cells in GVHD and GvL

TP12 Ullrich/Kühn

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Martina Casari

Topic: Macrophages and platelets modulation in hepatocellular carcinoma and infection

TP08 Schuppan/Deppermann

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David Charalambous (MD)

Topic: Optimierung der Expansion und Funktionalität humaner Tumorantigen-spezifischer T-Zellen durch eine neuartige granulozytär-vermittelte Hyperaktivierung

TP06: Munder/Theobald

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Maximilian Engelberg (MD)

Topic: Synergistische Effekte physikochemischer Parameter des Tumormikromilieus auf das Verhalten tumorassoziierter Fibroblasten

TP13 Probst/Schild

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Ann-Katrin Gebel 

Topic: Charakterisierung einer neuartigen Hyperaktivierung humaner T-Zellen durch neutrophile Granulozyten

TP06 Munder/Theobald

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Fenja Gierschek

Topic: Generation of non-virally engineered chimeric antigen receptor-modified natural killer cells against leukemia

TP12 Ullrich/Kühn

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Mona Grans

Topic: Signals inducing type-I interferons production in the immunological steady state

TP13 Probst/Schild

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Kristin Grunz

Topic: Endosomal TLR Signaling and monocyte function

TP02 Beling/Ruf

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Alva Hayungs (MD)

Topic: Studien zu den biochemischen Grundlagen der Hyperaktivierung humaner T-Zellen durch neutrophile Granulozyten

TP06 Munder/Theobald

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Sara Helbich

Topic: Tissue repair immune cells in murine infection and cancer models

TP19N Delacher/Marini

Lida Jalili (MD)

Topic: Optimierung der NK-Zell-Immuntherapie zur Behandlung des Chemotherapie-resistenten Rhabdomyosarkoms

TP12 Ullrich/Kühn

Moritz Jürgens (MD)

Topic: The NIKs role within CX3XR1+ macrophages during inflammation and cancer development in the gut

TP15 Stebut/Waisman

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Anita Gabriele Kansy

TP09 Munder/Theobald 

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Friederike Kirschner (MD)

Topic: Untersuchungen zur Zusammensetzung des Tumormikromilieus unter Betrachtung des Transkriptoms, Proteoms und Sekretoms ausgewählter Tumorzelllinien

TP13 Probst/Schild


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Laura Klein

Topic: (Re)installing cancer immunity in pancreatic cancer and cancer of the upper GI tract

TP22: Türeci/Gaida

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Josip Komso (MD)

Topic: Endothelial control of intestinal epithelial stem cell differentiation

TP15 Stebut/Waisman

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Redouane Krini (MD)

Speaker of the IRTG medical doctoral candidates

Topic: Gezielte Beeinflussung von konvergierenden Mechanismen ineffizienter Immunität bei Tumorerkrankungen und chronischen Infektionen


TP08 Schuppan/Deppermann

Simone Liebhäuser (MD)

Topic: Hyperaktivierung humaner T-Zellen durch Granulozyten bei Arginase-Hemmung: Analyse wichtiger Signaltransduktionswege

TP06 Munder/Theobald

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Johanna Lossa

Topic: The role of type-I interferons in myeloproliferative neoplasms and chronic viral infections

TP21 Muth/Radsak

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Sukrit Mahajan

Topic: Role of EGFL7 in immune evasion by malignant glioma

TP09 Schmitt/Zipp

Bishal Manandhar

Topic: Impact of SAMDH1 on the tumor microenvironment

TP04 König

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Alina Moter

Topic: Understanding immune cellular processes for cancer immunotherapy with focus on (i) genetically engineered CAR-NK cells and (ii) SARS-CoV-2 vaccination responses in patients with multiple myeloma

TP12 Ullrich/Kühn

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Annekathrin Nedwed

TP19N Delacher/Marini

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Assel Nurbekova

Topic: Regulation of murine cytomegalovirus (mCMV) immune evasion and transcriptional regulation of m152.

TP11 Distler/Lemmermann

Sven Pagel

Topic: Influence of F7 deletion in myeloid cells on tumor growth and antitumor immune response

TP10 Graf/Ruf

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Katharina Paßkowski

Topic: "Identification and characterization of T cell receptor independently reactivated memory T cells in the context of virus infection"

TP13 Probst/Schild

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Jennifer Pott

Topic: Impact of the endothelial protein C receptor (EPCR) expressed by myeloid cells on tumor growth and immnunomodulation

TP10 Graf/Ruf

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Lisa Marie Reindl

Topic: Improving NK-cell based immunotherapy against solid pediatric malignancies

TP12 Ullrich/Kühn

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Carina Santos

Topic: Role of platelets in cancer metastasis

TP10 Graf/Ruf

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Theresa Schaller

Topic: Targets and mediators of IL-17 mouse models of psoriasis and skin infection

TP15 Stebut/Waisman

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Amelie Schwenger (MD)

Topic: Charakterisierung der Immunreaktionen bei Covid-19 Erkrankungen und nach Covid-19 Vakzinierung

TP12 Ullrich/Kühn

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Dominik Siegl

Topic: Immunotherapies in HCC mouse models

TP08 Schuppan/Deppermann

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Valeria Smirnov (MD)

Topic: Characterization of age and gender related differences in ILC subsets in healthy human skin

TP15 Stebut/Waisman

Sophia Thul

Topic: improvement of CAR-NK cell therapy for patients with malignant diseases by (i) further optimizing the design of CAR constructs and (ii) the genetic engineering of CAR NK cells

TP12 Ullrich/Kühn

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David Uhlfelder (MD)

Topic: Unraveling the role of IL-6 signaling in the preclinical model of Castleman disease

TP 15 Stebut/Waisman

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Isabel Teresa Voit (MD)

Topic: Charakterisierung der NK-Zell-Immunantwort nach BA.4/.5-Vakzinierung immunsupprimierter PatientInnen

TP12 Ullrich/Kühn

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Paul Warnke (MD)

Topic: Analyse der metabolischen Veränderung des Tumormikromilieus und der resultierenden Modellierung der Immunantwort unter dem Einfluss von EGFL7 im Gliom

TP09 Schmidt/Zipp

Ikra Gizem Yildiz

Topic: Neo-epitope specific T-cells

TP17 Kreiter/Sahin


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Project Leaders:

Univ.-Prof. Dr. rer. nat. Tobias Bopp, Institute for Immunology


Univ.-Prof. Dr. rer. nat. Björn E. Clausen, Institute for Molecular Medicine


Coordinator:

Ivonne Dietzel
Mainz Research School of Translational Biomedicine (TransMed)