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I. Medizinische Klinik und Poliklinik

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Publikationen

  1. Sprinzl MF., Koch S., Seib ML., Weinmann-Menke J., Düber C., Lang H., Marquardt JU., Woerns MA., Galle PR., Weinmann A. Risk factor-integrating inflammatory scores predict overall survival for hepatocellular carcinoma under Sorafenib treatment. Liver Cancer (accepted manuscript)
  2. Domínguez-Pérez M., Simoni-Nieves A., Rosales P., Nuño-Lámbarri N., Rosas-Lemus M., Souza V., Miranda RU., Bucio L., Uribe Carvajal S., Marquardt JU., Seo D., Gomez-Quiroz LE., Gutiérrez-Ruiz MC. Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. J Cell Physiol. 2018 Sep 21. doi: 10.1002/jcp.27474. [Epub ahead of print]
  3. Labenz C., Beul L., Toenges G., Schattenberg JM., Nagel M., Sprinzl MF., Nguyen-Tat M., Zimmermann T., Huber Y., Marquardt JU., Galle PR., Wörns MA. Validation of the simplified Animal Naming Test as primary screening tool for the diagnosis of covert hepatic encephalopathy. Eur J Intern Med. 2018 Aug 18. pii: S0953-6205(18)30334-0. doi: 10.1016/j.ejim.2018.08.008.
  4. Labenz C., Baron J., Toenges G., Schattenberg, JM., Nagel M., Sprinzl M., Nguyen-Tat M., Zimmermann T., Huber Y., Marquardt JU., Galle PR., Wörns MA. Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients. Aliment Pharmacol Ther. 2018 Jun 4. [Epub ahead of print]
  5. Foerster F., Mittler J., Darstein F., Heise M., Marquardt JU., Wörns MA., Weinmann A., Sälter L., Hoppe-Lotichius M., Heinrich S., Kloeckner R., Pitton MB., Schattenberg JM., Sprinzl MF., Düber C., Otto G., Lang H., Galle PR., Zimmermann T. Recipient liver function before liver transplantation influences post-transplantation survival in patients with HCC. Eur J Intern Med. 2018 May 30. pii: S0953-6205(18)30218-8. doi: 10.1016/j.ejim.2018.05.024. [Epub ahead of print]
  6. Heinrich B., Czauderna C., Marquardt JU. Immunotherapy of Hepatocellular Carcinoma. Oncol Res Treat. 2018;41(5):292-297.
  7. Nault JC., Galle PR. Marquardt JU. The role of molecular enrichment on future therapies in hepatocellular carcinoma. J Hepatol. 2018 Mar 2. pii: S0168-8278(18)30134-X
  8. Foerster F., Hess M., Gerhold-Ay A., Marquardt JU., Becker D., Galle, PR., Schuppan D., Binder H., Bockamp E. The immune contexture of hepatocellular carcinoma predicts clinical outcome. Sci Rep Mar 29;8(1):5351
  9. Palestino-Domínguez M., Mario Pelaez-Luna M., Lazzarini-Lechuga R., Rodríguez-Ochoa I., Souza V., Miranda RU., Pérez-Aguilar B., Bucio L., Marquardt JU., Gutiérrez-Ruiz MC., Gomez-Quiroz LE. Recombinant human hepatocyte growth factor provides protective effects in celurein-induced acute pancreatitis in mice. J Cell Physiol. 2018 Jan 17. doi: 10.1002/jcp.26444. [Epub ahead of print]
  10. Vollmar J., Lautem A., Closs E., Schuppan D., Kim YO., Grimm D., Marquardt JU., Fuchs P., Straub B., Schad A., Gründemann D., Schattenberg J., Gehrke N., Wörns MA., Baumgart J., Galle PR., Zimmermann T. Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis. Oncotarget 2017 Dec 18;8(70):115667-115680.
  11. Marquardt JU. The role of TGFβ in human hepatocarcinogenesis: mechanistic and therapeutic implications from an integrative multi-omics approach. Gastroenterology 2018 Jan;154(1):17-20.
  12. Wan S., Meyer AS., Weiler SM., Rupp C., Sticht C., Singer S., Tóth M., Thomann S., Roessler S., Schorpp-Kistner M., Schmitt J., Gretz N., Angel P., Tschaharganeh D., Marquardt JU., Schirmacher P., Pinna F., Breuhahn K. Mislocalization of the cell polarity protein Scribble (Scrib) induces SPARC secretion in hepatocellular carcinoma. Hepatology 2017 Nov 20. doi: 10.1002/hep.29669. [Epub ahead of print]
  13. Kirstein MM., Voigtländer T., Schweitzer N., Hinrichs JB., Marquardt JU., Wörns MA., Kloeckner R., Fründt TW., Ittrich H., Wacker F., Rodt T., Manns MP., Wege H., Weinmann A., Vogel A.. Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease. UEG Journal. First Published June 20, 2017
  14. Enríquez-Cortina C., Bello-Monroy O., Rosales P., Souza V., Miranda RU., Toledo-Pérez R., Luna-López A., Simoni-Nieves A., Hernández-Pando R., Concepción Gutiérrez-Ruiz M., Calvisi DF., Marquardt JU., Bucio L., Gomez-Quiroz LE.. Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis. Oncotarget. 2017 Oct 24;8(61):104136-104148.
  15. Labenz C., Prenosil V., Koch S., Huber Y., Marquardt JU., Schattenberg JM., Galle PR., Weinmann A., Wörns MA. Impact of different components of the metabolic syndrome on the outcome of patients with advanced hepatocellular carcinoma treated with sorafenib. Dig Dis. Dig Dis. 2017 Jul 4. doi: 10.1159/000477578.
  16. Reichenbach F., Wiedenmann C., Schalk E., Becker D., Funk K., Scholz-Kreisel P., Todt F., Döhner K., Marquardt JU.*, Heidel F.H.*, Edlich F.* Mitochondrial Bax determines the predisposition to apoptosis in human AML. Clin Cancer Res. 2017 Aug 15;23(16):4805-4816.
  17. Castven C., Fischer M., Becker D., Heinrich S., Andersen JB., Strand D., Sprinzl MF., Strand S., Czauderna C., Heilmann S., Roessler S., Weinmann A., Wörns MA., Thorgeirsson SS., Galle PR., Matter MS., Lang H., Marquardt JU. Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas. Oncotarget. 2017 Jul 25;8(30):48688-48700.
  18. Weiler S., Pinna F., Wolf T., Lutz T., Geldiyev S., Wan S., Knaub M., Rössler R., Becker D., Sticht C., Gretz N., Lang H., Ustiyan V., Singer S., Lee JS., Marquardt JU., Schirmacher P., Kalinichenko V., Breuhahn K. Induction of chromosomal instability (CIN) by cooperative activation of yes-associated protein (YAP) and FOXM1 in hepatocarcinogenesis. Gastroenterology. 2017 Jun;152(8):2037-2051.
  19. Pinter P., Weinmann A., Wörns MW., Hucke F., Bota S., Marquardt JU., Duda DG., Jain RK., Galle PR., Trauner M., Peck-Radosavljevic M., Sieghart M. Use of inhibitors of the renin-angiotensin system is associated with longer survival in patients with hepatocellular carcinoma. UEG Journal. 2017 Nov;5(7):987-996.
  20. Czauderna C., Marquardt JU., Galle PR., Wörns MA. CME-Beitrag „Hepatozelluläre Karzinome“. Internist (Berl). 2017 May;58(5):469-479.
  21. Marquardt JU. Deconvolution of the cellular origin in hepatocellular carcinoma - hepatocytes take the center stage. Hepatology. 2016 Oct;64(4):1020-3.
  22. Gomez-Quiroz LE., Seo D., Lee YH., Kitade M., Gaiser T., Matthew Gillen M., Gutierrez-Ruiz MC:, Palestino-Domínguez M., Lee SB., Conner EA., Factor VM., Thorgeirsson SS., Marquardt JU. Loss of c-Met signaling sensitizes hepatocytes to lipotoxicity and induces cholestatic liver damage by aggravating oxidative stress.  Toxicology 2016 Jul 6. pii: S0300-483X(16)30121-4. [Epub ahead of print]
  23. Wörns MA., Labenz Ch., Marquradt JU. Gutartige Lebertumore. Der Gastroenterologe 05/2016
  24. Maass T., Marquardt JU., Lee JS., Krupp M., Scholz-Kreisel P., Mogler C., Schirmacher P., Müller M., Westphal H., Galle PR., Teufel A.. Increased liver carcinogenesis, and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice. Oncotarget. 2016 May 17;7(20):28903-13.
  25. Kaji K., Factor VM., Andersen JB., Durkin ME., Marquardt JU., Tomokuni A., Matter MS., Hoang T., Conner EA., Thorgeirsson SS. DNMT1 is essential for postnatal liver histogenesis and regeneration. Hepatology 2016 Mar 21.
  26. Marquardt JU., Nguyen-Tat M., Galle PR., Wörns MA. HCC Surveillance and Diagnostic Algorithms in Patients with Liver Cirrhosis. Visc Med. 2016 Apr;32(2):110-5.
  27. Wörns MA., Kloeckner R., Marquradt JU. Gutartige Lebertumore. Gastroenterologie up2date 2016; 12(01): 55-71
  28. Rey JW., Deris N., Marquardt JU., Kittner JM., Dümcke S., Tresch A., Biesterfeld S., Goetz M., Mudter J., Neurath MF., Galle PR., Kiesslich R., Hoffman A.. High Definition Endoscopy with i-Scan and Lugol’s solution for the Detection of Inflammation in Patients with NERD: Histologic Evaluation in Comparison with a Control Group. Dis Esophagus. 2016 Feb-Mar;29(2):185-91
  29. Matter MS., Marquardt JU., Andersen JB., Korokhov N., Stauffer JK., Kaji K., Decaens T., Quintavalle C., Quagliata L., Elloumi F., Hoang F., Hansen K., Molinolo A., Conner EA., Factor VM., Thorgeirsson SS. Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. Hepatology 2016 Feb 4
  30. Marquardt JU., Galle PR. Conference Scenes from the 9th Annual Conference of the International Liver Cancer Association (ILCA) 2015 in Paris. Hepat Oncol. 2016 Jan; 3 (01): 9-12.
  31. Marquardt JU., Galle PR. Conference Scenes from the 9th Annual Conference of the International Liver Cancer Association (ILCA) 2015 in Paris. Hepat Oncol. (accepted manusript)
  32. Marquardt JU., Andersen JB., Thorgeirsson SS. Functional and Genetic Deconstruction of the Cellular Origin in Liver Cancer. Nat Rev Cancer  2015 Oct 23;15(11):653-67.
  33. Marquardt JU., Gomez-Quiroz L., Arreguin Camacho LO., Pinna F., Lee YH., Kitade M., Palestino Domínguez M., Breuhahn K., Conner EA., Galle PR., Andersen JB., Factor VM., Thorgeirsson SS. Curcumin Effectively Depletes Hepatic Cancer Stem-Like Cells by NF-kB Mediated Inhibition of Histone Deacetylases. J. Hepatol. 2015 Apr 30
  34. Weinmann A., Alt Y., Koch S., Nelles C., Düber C., Lang H., Otto G., Zimmermann T., Marquardt JU., Galle PR., Wörns MA., Schattenberg JM. Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma. BMC Cancer. 2015 Apr 1;15(1):210.
  35. Maass T., Marquardt JU., Lee JS., Krupp M., Scholz-Kreisel P., Mogler C., Schirmacher P., Müller M., Westphal H., Galle PR., Teufel A.. Increased liver carcinogenesis, and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice. Oncotarget 2015 Mar 16. [Epub ahead of print]
  36. Marquardt JU., Andersen JB. Liver cancer oncogenomics: Opportunities and dilemma for clinical applications. Hepat Oncol. 2015 Jan; 2 (01): 79-93.
  37. Nguyen-Tat M., Götz E., Ahrens J., Rey JW., Sivanathan V., Wörns M., Galle PR., Marquardt JU. Response to Terlipressin and albumin is associated with improved outcome in patients with cirrhosis and hepatorenal syndrome (HRS). Dtsch Med Wochenschr. 2015 Jan;140(2):e21-6.
  38. Rey JW., Deris N., Marquardt JU., Kittner JM., Dümcke S., Tresch A., Biesterfeld S., Goetz M., Mudter J., Neurath MF., Galle PR., Kiesslich R., Hoffman A.. High Definition Endoscopy with i-Scan and Lugol’s solution for the Detection of Inflammation in Patients with NERD: Histologic Evaluation in Comparison with a Control Group. Dis Esophagus. 2014 Dec 17. [Epub ahead of print]
  39. Akita H., Marquardt JU., Durkin M., Kitade M., Seo D., Conner EA., Andersen JB., Factor VM., Thorgeirsson SS. MYC Activates Cancer Stem Cell Potential in Liver Cancer by p53 Dependent Mechanism. Cancer Res. 2014 Oct 15;74(20):5903-13.
  40. Moehler M., Thomaidis T., Zeifri C., Barhoom T., Marquardt JU., Ploch P., Schattenberg J., Maderer A., Schimanski CC., Weinmann A., Woerns MW.,  Kranich AL. Warnecke JM., Galle PR. Inclusion of targeted therapies in the standard of care for metastatic colorectal cancer patients in a German cancer centre: The more the better?! J Cancer Res Clin Oncol. 2014 Sep 19. [Epub ahead of print]
  41. Itzel T., Scholz P., Maass T., Krupp M., Marquardt JU., Strand S., Becker D., Staib, F., Binder H., Wang XW., Thorgeirsson SS., Galle PR., Teufel A. Translating bioinformatics in oncology: Guilty by profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis. Bioinformatics. 2014 Sep 18. pii: btu586. [Epub ahead of print]
  42. Sivanathan V., Kittner JM., Sprinzl MF., Weinmann A., Koch S., Wiltink J., Nguyen-Tat M., Marquardt JU., Wörns MA., Zimmermann T., Lang H., Galle PR., Schattenberg JM. Etiology and complications of liver cirrhosis: data from a German centre. Dtsch Med Wochenschr. 2014 Sep;139(36):1758-1762. Epub 2014 Aug 26.
  43. Gockel I., Becker J., Wouters MM., Niebisch S., Gockel HR., Ramonet D., Zimmermann J., Vigo AG., Trynka G., de Leόn AR., de la Serna JP., Kumar V., Franke L., Westra HJ., Drescher D., Kneist W., Marquardt JU., Galle PR., Mattheisen M., Annese V., Latiano A., Fumagalli U., Laghi L., Cuomo R., Sarnelli G., Müller M., Eckardt AJ., Tack J., von Rahden BHA., Allescher HD., Schulz HG., Wijmenga C., Heneka MT., Lang H., de Bakker PIW., Nöthen MM., Boeckxstaens GE., Knapp M., Schumacher J. An eight amino acid insertion in the cytoplasmic tail and two additional amino acid substitutions in the peptide binding domain of HLA-DQ confer risk to idiopathic achalasia. Nat Genet. Aug; 46(8):901-4
  44. Lee YH., Seo D., M., Andersen, JB., Kitade M., Gómez-Quiroz LE., Judge AD., Marquardt JU., Raggi C., Conner EA., MacLachlan I., Factor VM., Thorgeirsson SS. Therapeutic Implications of Isoform-Selective Inhibition of Histone Deacetylase 2 by Nanoparticle Delivered RNAi for Liver Cancer. Cancer Res. 2014 Jun 23 [Epub ahead of print]
  45. Nguyen-Tat M., Hoffman A., Marquardt JU., Buggenhagen H., Münzel T., Kneist W., Galle PR., Kiesslich R., Rey JW. [Upper Gastrointestinal Bleeding and Haemorrhagic Shock at the End of the Holidays: Pre-Hospital and In-Hospital Management of a Gastrointestinal Emergency]. Z Gastroenterol. 2014 May;52(5):441-6.
  46. Marquardt JU., Thorgeirsson SS. Next-generation Genomic Profiling of Hepatocellular Adenomas: A New Era of Individualized Patient Care. Cancer Cell. 2014 Apr 14;25(4):409-11.
  47. Marquardt JU., Thorgeirsson SS. SnapShot: Hepatocellular Carcinoma. Cancer Cell. 2014 Apr 14;25(4):550
  48. Finch ML., Marquardt JU., Yeoh GC., Callus BA. Regulation of microRNAs and their role in liver development, regeneration and disease. Int J Biochem Cell Biol. 2014 Apr 13. pii: S1357-2725(14)00117-4. [Epub ahead of print] Review.
  49. Marquardt JU., Seo D., Andersen JB., Gillen MC., Kim MS., Conner EA., Factor VM., Park YN, Thorgeirsson SS. Sequential analysis of hepatocarcinogenesis indicates late stage acquisition of malignant traits. J Hepatol. 2014 Feb;60(2):346-53
  50. Raggi C., Factor VM., Seo D., Holczbauer A., Gillen MC., Marquardt JU., Andersen JB., Thorgeirsson SS. Epigenetic Reprogramming Modulates Malignant Properties of Human Liver Cancer. Hepatology 2014 Jan 21. [Epub ahead of print]
  51. Marquardt JU. Kombination von TACE und Sorafenib beim intermediären hepatozellulären Karzinom (HCC). Thieme Case Reports 2014
  52. Kitade M., Factor VM., Akita H., Holczbauer A., Andersen JB., Daekwan S., Marquardt JU., Conner EA., Lee SB., Lee YH., Thorgeirsson SS. Specific fate decisions in adult hepatic progenitor cells driven by Met and Egfr signaling. Genes Dev. 2013 Aug 1;27(15):1706-17
  53. Marquardt JU., Thorgeirsson SS. Linking MLL and the HGF-MET signaling pathway in liver cancer. J Clin Invest. 2013 Jul 1;123(7):2780-3
  54. Marquardt JU., Thorgeirsson SS. Sall4 in Stemness-Driven Hepatocarcinogenesis. N Engl J Med 2013 Jun 13;368(24):2316-8
  55. Marquardt JU., Fischer K., Baus K., Krupp M., Linke M, Teufel A., Zechner U., Strand D., Thorgeirsson SS., Galle PR., Strand S. SIRT6 dependent genetic and epigenetic alterations are associated with poor clinical outcome in HCC patients. Hepatology 2013 Mar 23. [Epub ahead of print]
  56. Holczbauer A., Factor VM, Andersen JB., Marquardt JU., Kleiner D., Raggi C., Kitade M., Seo D., Hirofumi A., Durkin M., Thorgeirsson SS. Modeling Pathogenesis of Primary Liver Cancer in Lineage Specific Cell Types. Gastroenterology 2013 Mar 19. [Epub ahead of print]
  57. Marquardt JU., Galle PR. Epigenetic regulation of methionine adenosyltransferase 1A; a role for microRNA-based treatment in liver cancer? Hepatology. 2013 Mar 6. doi: 10.1002/hep.26375. [Epub ahead of print]
  58. Wörns M., Koch S., Niederle I., Marquardt JU., Nguyen-Tat M., Gamstätter T., Schuchmann M., Schulze-Bergkamen H., Galle PR., Weinmann A. Baseline factors and survival in patients with hepatocellular carcinoma treated with sorafenib. Dig Liver Dis. 2012 Nov 20. Doi
  59. Teufel A., Marquardt JU., Galle PR. Next generation sequencing of HCC from European and Asian HCC cohorts. Back to p53 and Wnt/β-Catenin. J Hepatol. 2012 Oct 10. [Epub ahead of print]
  60. Marquardt JU., Andersen JB. Next-generation sequencing: Application in liver cancer- past, present and future? Biology 2012, 1(2), 383-394; doi:10.3390/biology1020383
  61. Nguyen-Tat M., Gamstätter T., Marquardt JU., Geissinger E., Schadmand-Fischer S., Lang H., Siegel E., Schuchmann M., Galle PR., Wörns Ma. IgG4-related sclerosing cholangitis mimicking cholangiocellular carcinoma. Z Gastroenterol. 2012 Sep;50(9):1008-1012. Epub 2012 Sep 10
  62. Teufel A., Hochrath K., Becker D., Dooley S., Breitkopf-Heinlein K., Krupp M., Maass T., Marquardt JU., Kolb M., Korn B., Niehrs C., Zimmermann T., Weber S., Galle PR., Lammert F.. Identification of RARRES1 as a core regulator in liver fibrosis. J Mol Med (Berl). 2012 Jun 6. [Epub ahead of print]
  63. Marquardt JU., Galle PR., Teufel A. Hepatocellular carcinoma- Molecular pathogenesis and novel targets for therapy. Dtsch Med Wochenschr. 2012 Apr;137(16):855-60. Epub 2012 Apr 11
  64. Marquardt, JU., Seo, D., Gomez-Quirez, L., Uchida, K., Gillen, MC., Kitade, M., Conner, EA., Factor, VM., Thorgeirsson, SS. Loss of c-Met Accelerates Development of Liver Fibrosis in Response to CCl4 Exposure through Deregulation of Multiple Molecular Pathways. Biochim Biophys Acta. 2012 Feb 22. [Epub ahead of print]
  65. Lee SB., Seo D., Choi D., Park KY., Holczbauer A., Marquardt JU., Conner EA:, Factor VM., Thorgeirsson SS. Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells (iPSC). Stem Cells. 2012 Feb 29. doi: 10.1002/stem.1074. [Epub ahead of print]
  66. Krupp M., Marquardt JU., Sahin U., Galle PR., Castle J., Teufel A. RNA-Seq Atlas – A reference database for gene expression profiling in normal tissue by next generation sequencing. Bioinformatics. 2012 Feb 17. [Epub ahead of print]
  67. Teufel A., Marquardt JU., Galle PR., Wörns M. Hepatocellular Carcinoma: What’s new? Dtsch Med Wochenschr. 2012 Jan 16. [Epub ahead of print]
  68. Ishikawa T., Factor VM., Marquardt JU., Raggi C., Seo D., Kitade M., Conner EA., Thorgeirsson SS. Hepatocyte Growth Factor (HGF)/c-Met Signaling is required for Stem Cell Mediated Liver Regeneration. Hepatology. 2011 Nov 16. [Epub ahead of print]
  69. Teufel A., Marquardt JU., Dooley S., Lammert F., Galle PR. Personalisierte Hepatologie – Gegenwärtige Konzepte, Entwicklungen und Erwartungen im Postgenom-Zeitalter. Z Gastroenterol. 2012 Jan;50(1):41-6. Epub 2012 Jan 5.
  70. Teufel A., Marquardt JU., Staib F., Galle PR. Snapshot liver transcriptome in HCC. J Hepatol. 2011 Dec 13. [Epub ahead of print]
  71. Teufel A., Marquardt JU., Galle PR. Novel insights in the genetics of HCC recurrence and advances in transcriptomic data integration. J. Hepatol. 2011 Jul 23. [Epub ahead of print]
  72. Marquardt JU., Galle PR., Teufel A. Molecular diagnosis and therapy of hepatocellular carcinoma (HCC); An emerging field for advanced technologies. J. Hepatol. 2011 Jul 23. [Epub ahead of print]
  73. Krupp M., Maass T., Marquardt J., Staib F., Bauer T., König R., Biesterfeld S., Galle PR., Tresch A., Teufel A. The functional cancer map: A systems-level synopsis of genetic deregulation in cancer. BMC Medical Genomics 2011 Jun 30;4(1):53. [Epub ahead of print]
  74. Marquardt, JU., Raggi, C., Andersen, JB.,  Seo, D., Avital, I., Geller, D., Lee, YH., Kitade, M., Holczbauer, A., Conner, EA., Factor, VM., Thorgeirsson, SS. Human Hepatic Cancer Stem Cells are Characterized by Common Stemness Traits and Diverse Oncogenic Pathways. Hepatology. 2011 May 26
  75. Lee, YH., Judge, AD., Seo, D., Kitade, M., Gómez-Quiroz, LE., Ishikawa, T., Andersen, JB., Kim, BK.., Marquardt, JU., Raggi, C., Avital, I., Conner, EA., MacLachlan, I., Factor, VM., Thorgeirsson SS. Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response. Oncogene. 2011 Apr 18. [Epub ahead of print]
  76. Andersen, JB., Factor, VM., Marquardt, JU., Raggi, C., Lee, YH., Seo, D., Conner, EA., Thorgeirsson, SS An integrated genomic and pharmacoepigenomic approach predicts therapeutic response of zebularine in human liver cancer. Sci Transl Med. 2010 Oct 20;2(54):54ra77.
  77. Lee, YH., Andersen, JB., Song, HT., Judge, AD., Seo, D., Ishikawa, D., Marquardt, JU., Kitade, M., Durkin, M., Raggi, C., Woo, HG., Conner, EA., Avital, I., MacLachlan, I., Factor, VM., Thorgeirsson, SS. Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma. Cancer Res. 2010 Oct 19. [Epub ahead of print]
  78. Kemp, CD., Kitano, M., Kerkar, S., Ripley, RT., Marquardt, JU., Schrump, DS., Avital, I. Pulmonary Resection for Metastatic Gastric Cancer. J Thorac Oncol. 2010. Sep 27. [Epub ahead of print]
  79. Factor, VM., Seo, D., Ishikawa, T., Kaposi-Novak, P., Marquardt, JU., Andersen, JB., Conner, EA., Thorgeirsson, SS., Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice. PLoS One. 2010 Sep 16;5(9). pii: e12739.
  80. Marquardt, JU., Quasdorff, M., Varnholt, H.,  Curth, HM., Mesghenna, S., Protzer, U., Goeser, T., Nierhoff, D. Neighbor of punc E11, a novel onco-fetal marker for hepatocellular carcinoma. Int J Cancer. 2010 July 23. [Epub ahead of print]
  81. Marquardt JU., Factor VM., Thorgeirsson SS. Epigenetic Regulation of Liver Cancer Stem Cells: Current Concepts and Clinical Implications. J Hepatol. 2010 Sep;53(3):568-77. Epub 2010 May 31
  82. Stellos K., Kopf S., Paul A., Marquardt JU., Gawaz M., Huard J., Langer H. Platelets in regeneration. Semin Thromb Hemost. 2010 Mar;36(2):175-84. Epub 2010 Apr 22
  83. Marquardt JU., Thorgeirsson SS. Stem Cells in Hepatocarcinogenesis: Evidence from Genomic Data. Semin Liver Dis. 2010; 30(1):26-35
  84. Popanda, O., Marquardt, JU., Chang-Claude, J., Schmezer, P. Genetic variation in normal tissue toxicity induced by ionizing radiation. Mutat Res. 2009 Jul 10;667(1-2):58-69. Epub 2008 Nov 5