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Publikationen unter Mitarbeit des klinischen Studienzentrums

 Shimura M, Kitano S, Ogata N, Mitamura Y, Oh H, Ochi H, Ohsawa S, Hirakata A; YOSEMITE and RHINE Investigators. Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial. Jpn J Ophthalmol. 2023 Mar 10:1–16. doi: 10.1007/s10384-023-00979-8. Epub ahead of print. PMID: 36897413; PMCID: PMC9999055.



Korb CA, Beck S, Wolters D, Lorenz K, Pfeiffer N, Grus FH. Serum Autoantibodies in Patients with Dry and Wet Age-Related Macular Degeneration. J Clin Med. 2023 Feb 17;12(4):1590. doi: 10.3390/jcm12041590. PMID: 36836125; PMCID: PMC9960765.



Burton B, Parodi MB, Jürgens I, Zanlonghi X, Hornan D, Roider J, Lorenz K, Munk MR, Croissant CL, Tedford SE, Walker M, Ruckert R, Tedford CE. LIGHTSITE II Randomized Multicenter Trial: Evaluation of Multiwavelength Photobiomodulation in Non-exudative Age-Related Macular Degeneration. Ophthalmol Ther. 2023 Apr;12(2):953-968. doi: 10.1007/s40123-022-00640-6. Epub 2023 Jan 2. PMID: 36588113; PMCID: PMC9805913.Szurman P, Gillmann K, Seuthe AM, Dick HB, Hoffmann EM, Mermoud A, Mackert MJ, Weinreb RN, Rao HL, Mansouri K; EYEMATE-SC Study Group. EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure. Ophthalmology. 2022 Oct 3:S0161-6420(22)00760-6. doi: 10.1016/j.ophtha.2022.09.021. Epub ahead of print. PMID: 36202141.



Holz FG, Schmitz-Valckenberg S, Wolf A, Agostini H, Lorenz K, Pielen A, Feltgen N, Guthoff R, Quiering C, Clemens A, Jaeger K. A randomized, open-label, multicenter study of switching to brolucizumab with or without a loading dose for patients with suboptimal anatomically controlled neovascular age-related macular degeneration-the FALCON study. Graefes Arch Clin Exp Ophthalmol. 2022 Aug;260(8):2695-2702. doi: 10.1007/s00417-022-05591-z. Epub 2022 Feb 21. PMID: 35188581; PMCID: PMC9325853.



Wykoff CC, Abreu F, Adamis AP, Basu K, Eichenbaum DA, Haskova Z, Lin H,

Loewenstein A, Mohan S, Pearce IA, Sakamoto T, Schlottmann PG, Silverman D, Sun

JK, Wells JA, Willis JR, Tadayoni R; YOSEMITE and RHINE Investigators. Efficacy,

durability, and safety of intravitreal faricimab with extended dosing up to

every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE):

two randomised, double-masked, phase 3 trials. Lancet. 2022 Feb

19;399(10326):741-755. doi: 10.1016/S0140-6736(22)00018-6. Epub 2022 Jan 24.

PMID: 35085503.



Bell K, Korb C, Butsch C, Giers BC, Beck A, Strzalkowska A, Ruckes C,

Klingberg U, Pfeiffer N, Lorenz K. A Randomized, Double-Masked, Active-

Controlled, Crossover Phase III Equivalence Study of Generic Dorzolamide 2%

versus Innovator Trusopt® Eye Drop Solution in Subjects with Open-Angle Glaucoma

or Ocular Hypertension. J Ophthalmol. 2022 Jul 20;2022:5249922. doi:

10.1155/2022/5249922. PMID: 35909461; PMCID: PMC9329021.



Lang GE, Stahl A, Voegeler J, Quiering C, Zaremba L, Lorenz K, Spital G,

Liakopoulos S. Observational outcomes in proliferative diabetic retinopathy

patients following treatment with ranibizumab, panretinal laser photocoagulation

or combination therapy - The non-interventional second year follow-up to the

PRIDE study. Acta Ophthalmol. 2022 Mar;100(2):e578-e587. doi: 10.1111/aos.14907.



Adorf A, Lorenz K, Feltgen N, Wilhelm B; die AG DOG Klinische

Studienzentren. Zusammenarbeit mit klinischen Auftragsforschungsinstituten :

Vorstellung eines Fragebogens für klinische Studienzentren [Collaboration with

clinical research organizations : Introduction of a questionnaire for clinical

study centers]. Ophthalmologie. 2022 Jun;119(6):577-581. German. doi:

10.1007/s00347-021-01551-w. Epub 2021 Dec 18. PMID: 34923599.





Lagrèze WA, Küchlin S, Ihorst G, Grotejohann B, Beisse F, Volkmann M,

Heinrich SP, Albrecht P, Ungewiss J, Wörner M, Hug MJ, Wolf S, Diem R; TONE

study group. Safety and efficacy of erythropoietin for the treatment of patients

with optic neuritis (TONE): a randomised, double-blind, multicentre, placebo-

controlled study. Lancet Neurol. 2021 Dec;20(12):991-1000. doi:

10.1016/S1474-4422(21)00322-7. PMID: 34800417.



Mansouri K, Gillmann K, Rao HL, Szurman P, Weinreb RN; ARGOS -2 Study Group.

Measurement of intraocular temperature in glaucoma: week-day and seasonal

fluctuations. Br J Ophthalmol. 2022 Apr 20:bjophthalmol-2021-320495. doi:

32.1136/bjophthalmol-2021-320495. Epub ahead of print. PMID: 35443998.





Bacharach J, Tatham A, Ferguson G, Belalcázar S, Thieme H, Goodkin ML, Chen

MY, Guo Q, Liu J, Robinson MR, Bejanian M, Wirta DL; ARTEMIS 2 Study Group.

Phase 3, Randomized, 20-Month Study of the Efficacy and Safety of Bimatoprost

Implant in Patients with Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS

2). Drugs. 2021 Nov;81(17):2017-2033. doi: 10.1007/s40265-021-01624-9. Epub 2021

Nov 1. PMID: 34724172; PMCID: PMC8602154.



Zimmermann M, Giers BC, Beck A, Bell K, Zimmermann H, Hechtner M, Hoffmann

EM, Pfeiffer N, Lorenz K. Short- and long-term agreement and reproducibility of

48-hours intraocular pressure measurements in glaucoma patients. BMC Ophthalmol.

2021 Jun 21;21(1):262. doi: 10.1186/s12886-021-02003-4. PMID: 34154547; PMCID:

PMC8218517.



Kahle N, Peters T, Braun A, Franklin J, Michalik C, Gekeler F, Wilhelm B;

retina.net e. V.; TES-RP-Studiengruppe. Transkorneale Elektrostimulation bei

Retinitis pigmentosa : Prüfplan einer multizentrischen, prospektiven,

randomisierten, kontrollierten und doppelblinden Studie im Auftrag des

Gemeinsamen Bundesausschusses (G-BA-Erprobungsrichtlinie) [Transcorneal

electrostimulation in retinitis pigmentosa : Protocol of a multicentric

prospective, randomized, controlled and double-masked trial on behalf of the

Joint Federal Committee (G-BA pilot regulation)]. Ophthalmologe. 2021

May;118(5):512-516. German. doi: 10.1007/s00347-021-01360-1. Epub 2021 Mar 19.

PMID: 33740090; PMCID: PMC8105205.



Jiménez-García M, Issarti I, Kreps EO, Ní Dhubhghaill S, Koppen C, Varssano

D, Rozema JJ; The REDCAKE Study Group. Forecasting Progressive Trends in

Keratoconus by Means of a Time Delay Neural Network. J Clin Med. 2021 Jul

22;10(15):3238. doi: 10.3390/jcm10153238. PMID: 34362023; PMCID: PMC8347247.



Szurman P, Mansouri K, Dick HB, Mermoud A, Hoffmann EM, Mackert M, Weinreb

RN, Rao HL, Seuthe AM; EYEMATE-SC study group. Safety and performance of a

suprachoroidal sensor for telemetric measurement of intraocular pressure in the

EYEMATE-SC trial. Br J Ophthalmol. 2021 Nov 12:bjophthalmol-2021-320023. doi:

10.1136/bjophthalmol-2021-320023. Epub ahead of print. PMID: 34772665.



Feijoó JG, Denis P, Hirneiß C, Aptel F, Perucho González L, Hussain Z, Lorenz K, Pfeiffer N, on behalf of the STAR-II Investigators. A European Study of the Performance and Safety of MINIject in Patients With Medically Uncontrolled Open-angle Glaucoma (STAR-II). Journal of Glaucoma: October 2020 - Volume 29 - Issue 10 - p 864-87, doi: 10.1097/IJG.0000000000001632





Bell K, Beutgen VM, Nickels S, Lorenz K, Scheller Y, Elbaz H, Peto T, Ponto KA, Schulz A, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N, Grus FH, Schuster AK. Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. J Ophthalmol. 2020 Jul 29;2020:8386160. doi: 10.1155/2020/8386160. eCollection 2020. PMID: 32802490 



Feijoó JG, Denis P, Hirneiß C, Aptel F, Perucho L, Hussain Z, Lorenz K, Pfeiffer N; STAR-II investigators. A European Study of the Performance and Safety of MINIject in Patients with Medically Uncontrolled Open-Angle Glaucoma (STAR-II). J Glaucoma. 2020 Aug 1. doi: 10.1097/IJG.0000000000001632. Online ahead of print. PMID: 32769736



Jiménez-García M, Ní Dhubhghaill S, Koppen C, Varssano D, Rozema JJ; The REDCAKE Study Group. Baseline Findings in the Retrospective Digital Computer Analysis of Keratoconus Evolution (REDCAKE) Project. Cornea. 2020 Jun 10. doi: 10.1097/ICO.0000000000002389. Online ahead of print. PMID: 32541189



Bandello F, Coassin M, Di Zazzo A, Rizzo S, Biagini I, Pozdeyeva N, Sinitsyn M, Verzin A, De Rosa P, Calabrò F, Avitabile T, Bonfiglio V, Fasce F, Barraquer R, Mateu JL, Kohnen T, Carnovali M, Malyugin B; Group LEADER-7 Investigators. Correction: One week of levofloxacin plus dexamethasone eye drops for cataract surgery: an innovative and rational therapeutic strategy. Eye (Lond). 2020 May 28. doi: 10.1038/s41433-020-0987-9. Online ahead of print. PMID: 32467636



Bandello F, Coassin M, Di Zazzo A, Rizzo S, Biagini I, Pozdeyeva N, Sinitsyn M, Verzin A, De Rosa P, Calabrò F, Avitabile T, Bonfiglio V, Fasce F, Barraquer R, Mateu JL, Kohnen T, Carnovali M, Malyugin B; Group LEADER-7 Investigators. One week of levofloxacin plus dexamethasone eye drops for cataract surgery: an innovative and rational therapeutic strategy. Eye (Lond). 2020 May 4. doi: 10.1038/s41433-020-0869-1. Online ahead of print. PMID: 32366996



Scheidemann-Wesp U, Gianicolo EAL, Cámara RJ, Wegener A, Buchner SE, Schwenn O, Höck A, Buchner H, Lorenz K, Vossmerbaeumer U, Böhm M, Kohnen T, Wollschläger D, Singer S, Blettner M, Hammer GP. Ionising radiation and lens opacities in interventional physicians: results of a German pilot study. J Radiol Prot. 2019 Oct 18;39(4):1041-1059. doi: 10.1088/1361-6498/ab2771. [Epub ahead of print]



Böhringer D, Goos D, Ach T, Feltgen N, Fleckenstein M, Kohnen T, Lorenz K, Pielen A, Spital G, Wilhelm B, Böhringer S, Reinhard T; Arbeitsgemeinschaft DOG – Klinische Studienzentren. [Work sampling in ophthalmological clinical studies. A multicenter field study]. Ophthalmologe. 2019 Sep;116(9):872-878. doi: 10.1007/s00347-019-0851-0. German.



Laspas P, Garcia-Feijoo J, Martinez-de-la-Casa JM, Larrosa JM, Fea A, Lemij H, Gandolfi S, Lorenz K, Samuelson TW, Pfeiffer N. Three-Year Results of Hydrus Microstent with Phacoemulsification. Ophthalmol Glaucoma. 2019 Nov-Dec;2(6):440-442. doi: 10.1016/j.ogla.2019.08.006. Epub 2019 Aug 23. PMID: 32672579 No abstract available



Lang GE, Stahl A, Voegeler J, Quiering C, Lorenz K, Spital G, Liakopoulos S. Efficacy and safety of ranibizumab with or without panretinal laser photocoagulation versus laser photocoagulation alone in proliferative diabetic retinopathy - the PRIDE study. Acta Ophthalmol. 2019 Dec 6. doi: 10.1111/aos.14312. [Epub ahead of print]



Garweg JG, Stefanickova J, Hoyng C, Schmelter T, Niesen T, Sowade O, Sivaprasad S; AQUA Investigators. Vision-Related Quality of Life in Patients with Diabetic Macular Edema Treated with Intravitreal Aflibercept: The AQUA Study.Ophthalmol Retina. 2019 Jul;3(7):567-575. doi: 10.1016/j.oret.2019.03.012. Epub 2019 Mar 21



Ulbig M, Höh H, Schmickler S, Wolf A, Dimopoulos S, Lorenz K, Bauer-Steinhusen U, Wiedemann P; POLARIS-Studiengruppe. Treatment reality with ranibizumab in clinical routine use for patients with diabetic macular edema: 1 year results of the German POLARIS cohort. Ophthalmologe. 2019 Jul;116(7):631-639. doi: 10.1007/s00347-018-0793-y. German



Rozema JJ, Hershko S, Tassignon MJ; for EVICR.net, Project Gullstrand Study Group. The components of adult astigmatism and their age-related changes. Ophthalmic Physiol Opt. 2019 May;39(3):183-193. doi: 10.1111/opo.12616.



Bourne R, Kaarniranta K, Lorenz K, Traverso C, Vuorinen J, Ropo A. Changes in ocular signs and symptomsin patients switching from bimatoprost–timolol to tafluprost–timolol eye drops: an open-label phase IV study. BMJ Open. 2019 April



Heindl LM, Augustin AJ, Messmer EM; ADVISE study group. ADenoVirus Initiative Study in Epidemiology (ADVISE)-results of a multicenter epidemiology study in Germany. Graefes Arch Clin Exp Ophthalmol. 2019 Jan;257(1):249-251. doi: 10.1007/s00417-018-4150-2. Epub 2018 Sep 25. No abstract available.



Deutsche Ophthalmologische Gesellschaft (DOG)"Empfehlungen der DOG für die Planung klinischer Studien im Auftrage Dritter" Ophthalmologe 2018; 115, 655-658 (Pdf, 154,1 KB)



Melzer C, Ziemssen F, Eter N, Brinkmann C, Agostini H, Haeusser-Fruh G, Rose U, Schargus M, Lorenz K, Holz FG, Schmitz-Valckenberg S. Design and Baseline Characteristics of the HELP Study: An Extended and Long-Term Observation of Pathological Myopia in Caucasians. Ophthalmologica. 2018 Jun 15:1-12. doi: 10.1159/000489180.



Stefanickova J, Cunha-Vaz J, Ulbig M, Pearce I, Fernández-Vega Sanz A, Theodossiadis P, Kodjikian L, Izmailov A, Muston D, Vassilev Z, Lamotte B, Tückmantel C, Friedl S, Altemark A, Schwarz HJ, Katz T; POLARIS study investigators. A noninterventional study to monitor patients with diabetic macular oedema starting treatment with ranibizumab (POLARIS). Acta Ophthalmol. 2018 Apr 25. doi: 10.1111/aos.13771.

Bonini S, Lambiase A, Rama P, Filatori I, Allegretti M, Chao W, Mantelli F; REPARO Study Group. Phase I Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis. Ophthalmology. 2018 Sep;125(9):1468-1471. doi: 10.1016/j.ophtha.2018.03.004. Epub 2018 Apr 10



Bonini S, Lambiase A, Rama P, Sinigaglia F, Allegretti M, Chao W, Mantelli F; REPARO Study Group. Phase II Randomized, Double-Masked, Vehicle-Controlled Trial of Recombinant Human Nerve Growth Factor for Neurotrophic Keratitis. Ophthalmology. 2018 Sep;125(9):1332-1343. doi: 10.1016/j.ophtha.2018.02.022. Epub 2018 Apr 10.



Lorenz K, Garhofer G, Hoeller S, et al. Long-term management of dry eye by once-daily use of Chitosan-N-Acetylcysteine eye drops. J Clin Ophthalmol. 2018;2(1):47-53.   



Pfeiffer N, Voykov B, Renieri G, Bell K, Richter P, Weigel M, Thieme H, Wilhelm B, Lorenz K, Feindor M, Wosikowski K, Janicot M, Päckert D, Römmich R, Mala C, Fettes P, Leo E. First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery. PLoS One. 2017 Nov 30;12(11):e0188899. doi: 10.1371/journal.pone.0188899. eCollection 2017



Wasielica-Poslednik J, Schmeisser J, Hoffmann EM, Weyer-Elberich V, Bell K, Lorenz K, Pfeiffer N. Fluctuation of intraocular pressure in glaucoma patients before and after trabeculectomy with mitomycin C. PLoS One. 2017 Oct 4;12(10):e0185246. doi: 10.1371/journal.pone.0185246. eCollection 2017.



Lorenz K, Scheller Y, Bell K, Grus F, Ponto KA, Bock F, Cursiefen C, Flach J, Gehring M, Peto T, Silva R, Tal Y, Pfeiffer N. A prospective, randomised, placebo-controlled, double-masked, three-armed, multicentre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma - the STRONG study: study protocol for a randomised controlled trial. Trials. 2017 Mar 16;18(1):128. doi: 10.1186/s13063-017-1861-3.



Lorenz K, Wasielica-Poslednik J, Bell K, Renieri G, Keicher A, Ruckes C, Pfeiffer N, Thieme H. Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. PLoS One. 2017 Feb 15;12(2):e0171636. doi: 10.1371/journal.pone.0171636. eCollection 2017.

Wasielica-Poslednik J, Politino G, Schmidtmann I, Lorenz K, Bell K, Pfeiffer N, Pitz S. Influence of Corneal Opacity on Intraocular Pressure Assessment in Patients with Lysosomal Storage Diseases. PLoS One. 2017 Jan 12;12(1):e0168698. doi: 10.1371/journal.pone.0168698. eCollection 2017



Lorenz K, Beck S, Keilani MM, Wasielica-Poslednik J, Pfeiffer N, Grus FH. Longitudinal Analysis of Serum Autoantibody-Reactivities in Patients with Primary Open Angle Glaucoma and Optic Disc Hemorrhage. PLoS One. 2016 Dec 28;11(12):e0166813. doi: 10.1371/journal.pone.0166813. eCollection 2016.



Funke S, Beck S, Lorenz K, Kotterer M, Wolters D, Perumal N, Pfeiffer N, Grus FH. Analysis of the effects of preservative-free tafluprost on the tear proteome. Am J Transl Res. 2016 Oct 15;8(10):4025-4039. eCollection 2016



Lorenz K, Beck S, Keilani MM, Wasielica-Poslednik J, Pfeiffer N, Grus FH. Course of serum autoantibodies in patients after acute angle-closure glaucoma attack. Clin Exp Ophthalmol. 2017 Apr;45(3):280-287. doi: 10.1111/ceo.12864. Epub 2017 Feb 6.



Elflein HM, Rudy M, Lorenz K, Ponto KA, Scheurich A, Pitz S. Charles Bonnet's syndrome: not only a condition of the elderly. Graefes Arch Clin Exp Ophthalmol. 2016 Aug;254(8):1637-42. doi: 10.1007/s00417-016-3387-x. Epub 2016 Jun 25.



Jongenelen S, Rozema JJ, Tassignon MJ; EVICR.net and Project Gullstrand Study Group. Distribution of the Crystalline Lens Power In Vivo as a Function of Age. Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7029-35. doi: 10.1167/iovs.15-18047.



Mirshahi A, Raak P, Ponto K, Stoffelns B, Lorenz K, Scharioth GB. Deep Sclerectomy with Goniosynechiolysis Ab Interno for Chronic Glaucoma Associated with Peripheral Anterior Synechiae. J Ophthalmol. 2015;2015:625719. doi: 10.1155/2015/625719. Epub 2015 Jun 23.



Pfeiffer N, Garcia-Feijoo J, Martinez-de-la-Casa JM, Larrosa JM, Fea A, Lemij H, Gandolfi S, Schwenn O, Lorenz K, Samuelson TW. A Randomized Trial of a Schlemm's Canal Microstent with Phacoemulsification for Reducing Intraocular Pressure in Open-Angle Glaucoma. Ophthalmology. 2015 Jul;122(7):1283-93. doi: 10.1016/j.ophtha.2015.03.031. Epub 2015 May 9.



Pfeiffer N, Traverso CE, Lorenz K, Saarela V, Liinamaa J, Uusitalo H, Astakhov Y, Boiko E, Ropo A; Preservative-free Tafluprost/Timolol Fixed Combination Study Group. A 6-month study comparing efficacy, safety, and tolerability of the preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% versus each of its individual preservative-free components. Adv Ther. 2014 Dec;31(12):1228-46. doi: 10.1007/s12325-014-0163-3. Epub 2014 Dec 2.



Böhringer D, Ihorst G, Grotejohann B, Maurer J, Spierings E, Reinhard T; FANCY study group. Functional antigen matching in corneal transplantation: matching for the HLA-A, -B and -DRB1 antigens (FANCY) - study protocol. BMC Ophthalmol. 2014 Dec 13;14:156. doi: 10.1186/1471-2415-14-156.



Lorenz K, Pfeiffer N. Efficacy and safety of tafluprost 0.0015% and timolol maleate 0.5% fixed combination in patients with ocular hypertension or open-angle glaucoma. Expert Opin Pharmacother 2014 Oct;15(15):2255-62. doi: 10.1517/14656566.2014.955471. Epub 2014 Aug 29.



Lorenz K, Pfeiffer N. Efficacy and safety of tafluprost 0.0015% and timolol maleate 0.5% fixed combination in patients with ocular hypertension or open-angle glaucoma. Expert Opin Pharmacother. 2014 Oct;15(15):2255-62. doi: 10.1517/14656566.2014.955471. Epub 2014 Aug 29. Review. Erratum in: Expert Opin Pharmacother. 2014 Nov;15(16):2473.



Pielen A, Mirshahi A, Feltgen N, Lorenz K, Korb C, Junker B, Schaefer C, Zwiener I, Hattenbach LO; the RABAMES Study Group. Ranibizumab for Branch Retinal Vein Occlusion Associated Macular Edema Study (RABAMES): six-month results of a prospective randomized clinical trial. Acta Ophthalmol. 2014 Jul 8. doi: 10.1111/aos.12488. [Epub ahead of print]



Elflein HM, Pfeiffer N, Hoffmann EM, Hoehn R, Kottler U, Lorenz K, Zwiener I, Wild PS, Mirshahi A. Correlations between central corneal thickness and general anthropometric characteristics and cardiovascular parameters in a large European cohort from the Gutenberg Health Study. Cornea. 2014 Apr;33(4):359-65. doi: 10.1097/ICO.0000000000000068.



Rozema JJ, Tassignon MJ; for EVICR.net, Project Gullstrand Study Group. The bigaussian nature of ocular biometry. Optom Vis Sci. 2014 Jul;91(7):713-22. doi: 10.1097/OPX.0000000000000296.



Gramlich OW, Lorenz K, Grus FH, Kriechbaum M, Ehrlich D, Humpel C, Fischer-Colbrie R, Bechrakis NE, Troger J. Catestatin-like immunoreactivity in the rat eye. Neuropeptides. 2014 Feb;48(1):7-13. doi: 10.1016/j.npep.2013.11.003. Epub 2013 Nov 25.



Bhattacharya SK, Lee RK, Grus FH; Seventh ARVO/Pfizer Ophthalmics Research

Institute Conference Working Group. Molecular biomarkers in glaucoma. Invest

Ophthalmol Vis Sci.2013 Jan 7;54(1):121-31. doi: 10.1167/iovs.12-11067. PMID:

23297392; PMCID: PMC3544416.



Lorenz K, Korb C, Herzog N, Vetter JM, Elflein H, Keilani MM, Pfeiffer N.

Tolerability of 24-hour intraocular pressure monitoring of a pressure-sensitive

contact lens. J Glaucoma. 2013 Apr-May;22(4):311-6. doi:

10.1097/IJG.0b013e318241b874. PMID: 23524857.



Korb C, Zwiener I, Lorenz K, Mirshahi A, Pfeiffer N, Stoffelns B. Risk factors of a reduced response to ranibizumab treatment for neovascular age-related macular degeneration--evaluation in a clinical setting. BMC Ophthalmol. 2013 Dec 20;13:84. doi: 10.1186/1471-2415-13-84.



Korobelnik JF, Holz FG, Roider J, Ogura Y, Simader C, Schmidt-Erfurth U, Lorenz K, Honda M, Vitti R, Berliner AJ, Hiemeyer F, Stemper B, Zeitz O, Sandbrink R; GALILEO Study Group. Intravitreal Aflibercept Injection for Macular Edema Resulting from Central Retinal Vein Occlusion: One-Year Results of the Phase 3 GALILEO Study. Ophthalmology. 2013 Sep 28. doi:pii: S0161-6420(13)00730-6. 10.1016/j.ophtha.2013.08.012. [Epub ahead of print]



Lorenz K, Dick HB, Grus F, Vetter JM, Stoffelns B, Schoepfer K, Korb C, Pfeiffer N. Series of fibrinous inflammation after implantation of capsular tension ring. J Cataract Refract Surg. 2014 Feb;40(2):192-8. doi: 10.1016/j.jcrs.2013.07.041. Epub 2013 Dec 13.



Hoffmann EM, Lamparter J, Mirshahi A, Elflein H, Hoehn R, Wolfram C, Lorenz K, Adler M, Wild PS, Schulz A, Mathes B, Blettner M, Pfeiffer N. Distribution of central corneal thickness and its association with ocular parameters in a large central European cohort: the Gutenberg health study. PLoS One. 2013 Aug 1;8(8):e66158. doi: 10.1371/journal.pone.0066158. Print 2013.



Lorenz K, Wolfram C, Breitscheidel L, Shlaen M, Verboven Y, Pfeiffer N. Direct cost and predictive factors for treatment in patients with ocular hypertension or early, moderate and advanced primary open-angle glaucoma: the CoGIS study in Germany. Graefes Arch Clin Exp Ophthalmol. 2013 Apr 30. [Epub ahead of print]



Wolfram C, Lorenz K, Breitscheidel L, Verboven Y, Pfeiffer N. Health- and Vision-related Quality of Life in Patients with Ocular Hypertension or Primary Open-angle Glaucoma. Ophthalmologica. 2013;229:227-34. doi: 10.1159/000350553. Epub 2013 Apr 24.



Lorenz K, Kramann C, Rauch N, Vetter JM, Elflein H, Keilani MM, Pfeiffer N. Evaluation of SENSIMED Triggerfish® 24-Hour monitoring in healthy subjects and glaucoma patients. J Glaucoma. 2013 Mar 20. [Epub ahead of print].



Lorenz K, Gramlich OW, Grus FH, Ehrlich D, Humpel C, Nogalo M, Fischer-Colbrie R, Bechrakis NE, Hattmannstorfer R, Troger J. GE-25-like immunoreactivity in the rat eye. Peptides. 2012 Aug;36(2):286-91. doi: 10.1016/j.peptides.2012.04.022. Epub 2012 May 23.



Mirshahi A, Hoehn R, Lorenz K, Kramann C, Baatz H. Anti-tumor necrosis factor alpha for retinal diseases: current knowledge and future concepts. J Ophthalmic Vis Res. 2012 Jan;7(1):39-44.



Lorenz K, Rosbach K, Matt A, Pfeiffer N. Addition of a fixed combination of brinzolamide 1%/timolol 0.5% to prostaglandin monotherapy in patients with glaucoma or ocular hypertension. Clin Ophthalmol. 2011;5:1745-50. Epub 2011 Dec 9.



Vetter JM, Schirra A, Garcia-Bardon D, Lorenz K, Weingärtner WE, Sekundo W. Comparison of intraocular pressure during corneal flap preparation between a femtosecond laser and a mechanical microkeratome in porcine eyes. Cornea. 2011 Oct;30(10):1150-4.



Vetter JM, Tubic-Grozdanis M, Faust M, Lorenz K, Gericke A, Stoffelns BM. Effect of various compositions of riboflavin eye drops on the intraoperative corneal thickness during UVA-cross-linking in keratoconus eyes. Klin Monbl Augenheilkd. 2011 Jun;228(6):509-14. Epub 2011 Jun 7. German.



Mirshahi A, Lorenz K, Kramann C, Stoffelns B, Hattenbach LO. Ophthalmologic diagnostic procedures and imaging of retinal vein occlusions.] Ophthalmologe. 2011 Feb;108(2):111-116. German.



Lorenz K, Troger J, Gramlich O, Grus F, Hattmannstorfer R, Fischer-Colbrie R, Joachim S, Schmid E, Teuchner B, Haas G, Bechrakis N. PE11, a peptide derived from chromogranin B, in the rat eye. Peptides. 2011 Jun;32(6):1201-6. Epub 2011 Mar 23.



Renieri G, Führer K, Scheithe K, Lorenz K, Pfeiffer N, Thieme H. Efficacy and Tolerability of Preservative-Free Eye Drops Containing a Fixed Combination of Dorzolamide and Timolol in Glaucoma Patients. J Ocul Pharmacol Ther. 2010 Oct 26.



Lorenz K, Zwiener I, Mirshahi A. Subconjunctival Reflux and Need for Paracentesis after Intravitreal Injection of 0.1 ml Bevacizumab: Comparison between 27 gauge and 30 gauge Needle. Graefes Arch Clin Exp Ophthalmol. 2010.



Kramann C, Boehm N, Lorenz K, Wehrwein N, Stoffelns BM, Pfeiffer N, Grus FH. Effect of contact lenses on the protein composition in tear film: a ProteinChip study. Graefes Arch Clin Exp Ophthalmol. 2010 Jul 26.



Kramann CA, Schöpfer K, Lorenz K, Zwiener I, Stoffelns BM, Pfeiffer N. Intravitreal ranibizumab treatment of retinal angiomatous proliferation. Acta Ophthalmol. 2010 Jun 24.



Mirshahi A, Hoehn F, Lorenz K, Hattenbach LO. Incidence of Posterior Vitreous Detachment after Cataract Surgery. J Cataract Refract Surg. 2009 Jun;35(6):987-91.



Lorenz K, Troger J, Fischer-Colbrie R, Kremser B, Schmid E, Kralinger M, Teuchner B, Bechrakis N, Kieselbach G. Substance P and Secretoneurin in vitreous aspirates of patients with various vitreoretinal diseases. Peptides. 2008 Sep;29(9):1561-5. Epub 2008 May 4.



Lorenz K, Dick B, Jehkul A, Auffahrt GU. Inflammatory response after endocapsular phacoemulsification treated with 0.5% prednisolone acetate or vehicle. Graefes Arch Clin Exp Ophthalmol. 2008 Nov;246(11):1617-22. Epub 2008 Aug 26.





Lorenz K, Sicker M, Schmelzer E, Rupf T, Salvetter J, Schulz-Siegmund M,

Bader A. Multilineage differentiation potential of human dermal skin-derived

fibroblasts. Exp Dermatol. 2008 Nov;17(11):925-32. doi:

10.1111/j.1600-0625.2008.00724.x. Epub 2008 Jun 14. PMID: 18557932.

Stemberger K, Dick B, Kramann C, Thieme H, Weber A, Petry F, Pfeiffer N. Painless acanthamoeba keratitis. Ophthalmologe. 2007 May;104(5):415-7. German.



Stemberger K, Kahaly GJ, Pitz S. Update thyroid eye disease. Compr Ophthalmol Update, 2006 Nov-Dec;7(6):287-98. Review.



Schmid E, Leierer J, Kieselbach G, Teuchner B, Kralinger M, Fischer-Colbrie R, Krause JE, Ngyuen QA, Haas G, Stemberger K, Troger J. Neurokinin A and neurokinin B in the human retina. Peptides. 2006 Sep 4.



Hoffmann EM, Bowd C, Klein N, Stemberger K, Grus FH, Pfeiffer N. Glaucoma detection using the GDx nerve fiber analyzer and the retinal thickness analyzer (RTA). Eur J Ophthalmol. 2006 Mar-Apr;16(2):251-8.



Stemberger K, Pallhuber J, Doblinger A, Troger J, Kirchmair R, Kralinger M, Fischer-Colbrie R, Kieselbach G. Secretoneurin in the human aqueous humor and the absence of an effect of frequently used eye drops on the levels. Peptides. 2004 Dec;25(12):2115-8.



The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
“Reproducibility of evaluation of optic disc change with stereo optic disc photographs.”
Ophthalmology 2003; 110, 2: 340-44



A. Vogel(1), I. Kersten-Gomez(1), R. Troost(2), S. Pourjavan(3), G. Bertoni(4), S. Gandolfi(5), T. Zeyen(6), S. Miglior(7), N. Pfeiffer(1) and The European Glaucoma Prevention Study Group
"Central corneal thickness in a subgroup of the European Glaucoma Prevention Study." Association of Research in Vision and Ophthalmology, Fort Lauderdale 2003
1 Department of Ophthalmology, Johannes Gutenberg-University Mainz, Germany       2 Coordination Center for Clinical Trials, Johannes Gutenberg-University Mainz, Germany
3 Department of Ophthalmology, Leuven, Belgium      4 Department of Opthalmology, Milano, Italy      5 Department of Opthalmology, Parma, Italy
6 Department of Opthalmology, Middelheim Hospital, Belgium      7 Department of Ophthalmology, Clinica Oculistica Universita di Milano, Milano, Italy



N. Pfeiffer(1) ,A. Vogel(1), I. Kersten-Gomez(1), R. Troost(2), T. Zeyen(3) and The European Glaucoma Prevention Study Group
"Longitudinal evaluation of central corneal thickness in ocular hypertensive patients."
Association of Research in Vision and Ophthalmology, Fort Lauderdale 2003
1 Department of Ophthalmology, Johannes Gutenberg-University Mainz, Germany      2 Coordination Center for Clinical Trials, Johannes Gutenberg-University Mainz, Germany
3 Department of Opthalmology, Middelheim Hospital, Belgium



Traverso CE, Gandolfi SA, Kelly SP, Hommer AH, Renard J-P, Nordmann J-P, Bron AM, Denis P, Pfeiffer N, Bayer A, Grehn FJ, Orzalesi N, Cedrone C, Salmon J,Augusto A-B, Hitchings R, Walt JG, Buchholz PM, Kotak SV, Siegartel LE, Rosenblatt LC, Cuccia AJ, Doyle JJ
"Estimation of Resource Utiliziation Associated with Glaucoma Disease progression in a multi-national retrospective study in Europe."
Association of Research in Vision and Ophthalmology, Fort Lauderdale 2003



The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.)).
"The European Glaucoma Prevention Study design and baseline description of the participants.”
Ophthalmology 2002; 109, 9: 1612-1621



A. Vogel, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
„European Glaucoma Prevention Study (EGPS)“
100. Tagung der Deutschen Ophthalmologischen Gesellschaft, Berlin 2002; Ophthalmologe 2002; 99, Suppl. 1: S118



S.H. Yun, A. Jünemann, G. Karasheva, M. Küchle, O. Schwenn, D. Spiegel, A. Vogel, I. Wimmer, F. Grehn
“CAT-152-Studie bei fistulierender Operation”
100. Tagung der Deutschen Ophthalmologischen Gesellschaft, Berlin 2002; Ophthalmologe 99, Suppl. 1: S117



R. Troost, A. Vogel, M. Wagner, O. Schwenn
“Entwicklung eines klinischen Datenbanksystems für Glaukomerkrankungen auf einer Remote Data Entry Platform”
100. Tagung der Deutschen Ophthalmologischen Gesellschaft, Berlin 2002, Ophthalmologe 99, Suppl.1: S173



A. Vogel, R. Troost, R. Yun, O. Schwenn, O. Schwenn, N. Pfeiffer
„Datenmodell einer Glaukomdatenbank für eine Universitätsaugenklinik“
100. Tagung der Deutschen Ophthalmologischen Gesellschaft, Berlin 2002, Ophthalmologe 99, Suppl. 1: S165



I.Kersten, A.Vogel, S.Kaiser, U.Luka-Krausgrill, N. Pfeiffer, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
„Compliance in prevention of glaucoma: an evaluation in the EGPS“
Association of Research in Vision and Ophthalmology, Fort Lauderdale 2001; Invest Ophthalmol Vis Sci 2001; 42: 819



A. Vogel, S. Kaiser, U. Krausgrill, I. Kersten, N. Pfeiffer, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
„Compliance bei der Prävention einer chronischen Erkrankung: Evaluation im Rahmen der European Glaucoma Prevention Study (EGPS)“
99. Tagung der DOG 29.9.-2-10.2001



Zeyen TG, Linsen MC, Fabre K, D’hondt K, Michiels I, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
“Reproducibility of serial optic disc stereo slides evaluation by experienced ophthalmologists, last year residents, and in ophthalmic photographer.”
Association of Research in Vision and Ophthalmology, Fort Lauderdale 2000; Invest Ophthalmol Vis Sci, 41 (4): S289



Miglior S, Pfeiffer N, Cunha-Vaz J, Zeyen T, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
“The European Glaucoma Prevention Study: Baseline Description of the Participants.”
Association of Research in Vision and Ophthalmology, Fort Lauderdale 2000; Invest Ophthalmol Vis Sci 2000, 41 (4): S517



 A.Vogel, I.Kersten, S. Kaiser, U. Luka-Krausgrill, N. Pfeiffer, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
„Compliance in prevention of a chronic disease: a national evaluation in the European Glaucoma Prevention Study (EGPS)“
13. Kongreß der Society of Ophthalmology in Europe 2000, Istanbul, Abstractbuch



Zeyen TG, Miglior S, Pfeiffer N, Cunha-Vaz J, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
“The European Glaucoma Prevention Study: reproducibility of serial optic disc stereo slides evaluation.”
Association of Research in Vision and Ophthalmology, Fort Lauderdale 1999; Invest Ophthalmol Vis Sci 1999, 40: S396



Miglior S, Pfeiffer N, Cunha-Vaz J, Zeyen T, The European Glaucoma Prevention Study Group (Clinical Centers Germany: University of Mainz (u.a.); Optic Disc Readers: University of Mainz (u.a.))
“The European Glaucoma Prevention Study: objectivs and methods.”
Association of Research in Vision and Ophthalmology, Fort Lauderdale 1999; Invest Ophthalmol Vis Sci 1999, 40: S566