Publikationen

2023 - 2022 -  2021 - 2020  -  2019  -  2018  -  2017  -  2016  -  2015   -  2014  -  2013  -  2012  -  2011

CTH verbundene Autoren sind in Kursivschrift. 

Originalartikel 2024

Reviews 2024

Editorials und Fachbeiträge 2024

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Originalartikel 2023

Goedegebuur J, Abbel D, Accassat S, Achterberg WP, Akbari A, Arfuch VM, Baddeley E, Bax JJ, Becker D, Bergmeijer B, Bertoletti L, Blom JW, Calvetti A, Cannegieter SC, Castro L, Chavannes NH, Coma-Auli N, Couffignal C, Edwards A, Edwards M, Enggaard H, Font C, Gava A, Geersing GJ, Geijteman ECT, Greenley S, Gregory C, Gussekloo J, Hoffmann I, Højen AA, van den Hout WB, Huisman MV, Jacobsen S, Jagosh J, Johnson MJ, Jørgensen L, Juffermans CCM, Kempers EK, Konstantinides S, Kroder AF, Kruip MJHA, Lafaie L, Langendoen JW, Larsen TB, Lifford K, van der Linden YM, Mahé I, Maiorana L, Maraveyas A, Martens ESL, Mayeur D, van Mens TE, Mohr K, Mooijaart SP, Murtagh FEM, Nelson A, Nielsen PB, Ording AG, Ørskov M, Pearson M, Poenou G, Portielje JEA, Raczkiewicz D, Rasmussen K, Trinks-Roerdink E, Schippers I, Seddon K, Sexton K, Sivell S, Skjøth F, Søgaard M, Szmit S, Trompet S, Vassal P, Visser C, van Vliet LM, Wilson E, Klok FA, Noble SIR. Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. Thromb Res. 2023 Aug;228:54-60





Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Nat Metab. 2023 Jul;5(7):1174-1187.

Pallares Robles A, Ten Cate V, Lenz M, Schulz A, Prochaska JH, Rapp S, Koeck T, Leineweber K, Heitmeier S, Opitz CF, Held M, Espinola-Klein C, Lackner KJ, Münzel T, Konstantinides SV, Ten Cate-Hoek A, Ten Cate H, Wild PS. Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification. Thromb Res. 2023 Jul;227:71-81

Ernst M, Hinz A, Brähler E, Merzenich H, Faber J, Wild PS, Beutel ME. Quality of life after pediatric cancer: comparison of long-term childhood cancer survivors' quality of life with a representative general population sample and associations with physical health and risk indicators. Health Qual Life Outcomes. 2023 Jul 4;21(1):65

Werner AM, Ernst M, Brähler E, Tibubos AN, Otten D, Reiner I, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Beutel ME. The association of depressive symptoms and body weight change in midlife - Results from the Gutenberg Health Study in Germany. J Affect Disord. 2023 Jul 1;332:115-124







Molitor M, Bayo-Jimenez MT, Hahad O, Witzler C, Finger S, Garlapati VS, Rajlic S, Knopp T, Bieler TK, Aluia M, Wild J, Lagrange J, Blessing R, Rapp S, Schulz A, Kleinert H, Karbach S, Steven S, Ruf W, Wild P, Daiber A, Münzel T, Wenzel P. Aircraft noise exposure induces pro-inflammatory vascular conditioning and amplifies vascular dysfunction and impairment of cardiac function after myocardial infarction. Cardiovasc Res. 2023 Jun 13;119(6):1416-1426

Keller K, Kohring C, Farmakis IT, Valerio L, Barco S, Bätzing J, Akmatov MK, Konstantinides S, Münzel T, Hobohm L, Holstiege J. Impact of venous thromboembolism on incidence of arterial thromboembolism - An analysis of German outpatient claims data. Thromb Res. 2023 Jun;226:9-17

Nagy M, Robles AP, Visser M, Koeck T, Ten Cate V, Ten Cate-Hoek AJ, Schwers S, Heitmeier S, Ten Cate H, Wild PS, Spronk HMH. Predictive value for increased activated factor XI activity in acute venous thromboembolism. J Thromb Haemost. 2023 Jun;21(6):1610-1622

Hartmann A, Grabitz SD, Hoffmann EM, Wild PS, Schmidtmann I, Lackner KJ, Beutel ME, Münzel T, Tüscher O, Schattenberg JM, Pfeiffer N, Schuster AK. Intraocular Pressure and Its Relation to Climate Parameters-Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci. 2023 Jun 1;64(7):15

Wittig J, Drekolia MK, Kyselova A, Delgado Lagos F, Bochenek ML, Hu J, Schäfer K, Fleming I, Bibli SI. Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation. Redox Biol. 2023 Jun;62:102694.

Farmakis IT, Valerio L, Barco S, Alsheimer E, Ewert R, Giannakoulas G, Hobohm L, Keller K, Mavromanoli AC, Rosenkranz S, Morris TA, Konstantinides SV, Held M, Dumitrescu D. Cardiopulmonary exercise testing during follow-up after acute pulmonary embolism. Eur Respir J. 2023 Jun 8;61(6):2300059

Leidecker M, Bertling A, Hussain M, Bischoff M, Eble JA, Fender AC, Jurk K, Rumpf C, Herrmann M, Kehrel BE, Niemann S. Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells. Microbiol Spectr. 2023 Jun 15;11(3):e0388622

Mora D, Mateo J, Nieto JA, Bikdeli B, Yamashita Y, Barco S, Jimenez D, Demelo-Rodriguez P, Rosa V, Yoo HHB, Sadeghipour P, Monreal M; Registro Informatizado de Enfermedad TromboEmbólica (RIETE) Investigators. Machine learning to predict major bleeding during anticoagulation for venous thromboembolism: possibilities and limitations. Br J Haematol. 2023 Jun;201(5):971-981

Bikdeli B, Lo YC, Khairani CD, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky EA, Klok FA, Hunsaker AR, Aghayev A, Muriel A, Wang Y, Hussain MA, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber SZ, Zhou L, Monreal M, Krumholz HM, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study. Thromb Haemost. 2023 Jun;123(6):649-662

Kroone C, Tieken C, Kocatürk B, Paauwe M, Blok EJ, Ünlü B, van den Berg YW, Stanganello E, Kapteijn MY, Swier N, Zhang X, Duits DEM, Lin Y, Oostenbrink LVE, van den Akker RFP, Mosnier LO, Hawinkels LJ, van Vlijmen BJM, Ruf W, Kuppen PJ, Cannegieter SC, Buijs JT, Versteeg HH. Tumor-expressed factor VII is associated with survival and regulates tumor progression in breast cancer. Blood Adv. 2023 Jun 13;7(11):2388-2400

Krenzlin V, Schöche J, Walachowski S, Reinhardt C, Radsak MP, Bosmann M. Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates. Eur J Immunol. 2023 May;53(5):e2250339

Englert H, Göbel J, Khong D, Omidi M, Wolska N, Konrath S, Frye M, Mailer RK, Beerens M, Gerwers JC, Preston RJS, Odeberg J, Butler LM, Maas C, Stavrou EX, Fuchs TA, Renné T. Targeting NETs using dual-active DNase1 variants. Front Immunol. 2023 May 23;14:1181761

Keller K, Haghi SHR, Hahad O, Schmidtmann I, Chowdhury S, Lelieveld J, Münzel T, Hobohm L. Air pollution impacts on in-hospital case-fatality rate of ischemic stroke patients. Thromb Res. 2023 May;225:116-125

Hettich-Damm N, Petersen J, Zahn D, Baumkoetter R, Wild PS, Muenzel T, Schuster AK, Koenig J, Lackner K, Pfeiffer N, Beutel ME, Engwicht E. Gender Differences and the Impact of Partnership and Children on Quality of Life During the COVID-19 Pandemic. Int J Public Health. 2023 May 22;68:1605826

Zbinden S, Voci D, Grigorean A, Holy EW, Kaufmann PA, Münger M, Pleming W, Kucher N, Barco S. Clinical outcomes of ultrasound-assisted coagulation monitoring-adjusted catheter-directed thrombolysis for acute pulmonary embolism. Thromb Res. 2023 May;225:73-78

Gogiraju R, Witzler C, Shahneh F, Hubert A, Renner L, Bochenek ML, Zifkos K, Becker C, Thati M, Schäfer K. Deletion of endothelial leptin receptors in mice promotes diet-induced obesity. Sci Rep. 2023 May 22;13(1):8276

Klok FA, Pruszczyk P, Konstantinides SV. Thrombolytic treatment of life-threatening pulmonary embolism in times of alteplase shortage. Eur Heart J. 2023 May 21;44(20):1837-1839

Zhang P, Solari FA, Heemskerk JWM, Kuijpers MJE, Sickmann A, Walter U, Jurk K. Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. Int J Mol Sci. 2023 Apr 24;24(9):7776

Beck S, Öftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W, Stegner D, Nieswandt B. Platelet glycoprotein V spatio-temporally controls fibrin formation. Nat Cardiovasc Res. 2023 Apr;2(4):368-382

Barco S, Mavromanoli AC, Kreitner KF, Bunck AC, Gertz RJ, Ley S, Valerio L, Klok FA, Gerhardt F, Rosenkranz S, Konstantinides SV. Preexisting Chronic Thromboembolic Pulmonary Hypertension in Acute Pulmonary Embolism. Chest. 2023 Apr;163(4):923-932

Farmakis IT, Valerio L, Giannakoulas G, Hobohm L, Cushman M, Piazza G, Konstantinides SV, Barco S. Social determinants of health in pulmonary embolism management and outcome in hospitals: Insights from the United States nationwide inpatient sample. Res Pract Thromb Haemost. 2023 Apr 6;7(3):100147

Zuin M, Barco S, Giannakoulas G, Engelen MM, Hobohm L, Valerio L, Vandenbriele C, Verhamme P, Vanassche T, Konstantinides SV. Risk of venous thromboembolic events after COVID-19 infection: a systematic review and meta-analysis. J Thromb Thrombolysis. 2023 Apr;55(3):490-498

Hackenberg B, O'Brien K, Döge J, Lackner KJ, Beutel ME, Münzel T, Pfeiffer N, Schulz A, Schmidtmann I, Wild PS, Matthias C, Bahr-Hamm K. Tinnitus Prevalence in the Adult Population-Results from the Gutenberg Health Study. Medicina (Kaunas). 2023 Mar 20;59(3):620

Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation. Nature. 2023 Mar;615(7950):143-150

Voci D, Fedeli U, Valerio L, Schievano E, Righini M, Kucher N, Spirk D, Barco S. Mortality rate related to peripheral arterial disease: A retrospective analysis of epidemiological data (years 2008-2019). Nutr Metab Cardiovasc Dis. 2023 Mar;33(3):516-522



Garlapati V, Molitor M, Michna T, Harms GS, Finger S, Jung R, Lagrange J, Efentakis P, Wild J, Knorr M, Karbach S, Wild S, Vujacic-Mirski K, Münzel T, Daiber A, Brandt M, Gori T, Milting H, Tenzer S, Ruf W, Wenzel P. Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1-driven fibrotic remodeling in ischemic heart failure. J Clin Invest. 2023 Feb 15;133(4):e156436

Kopp S, Tilch MK, Sagoschen I, Kaes J, Kuniss M, Neumann T, Yang Y, Schnitzler K, Schmidt KH, Rostock T, Münzel T, Konstantinides S, Wild J, Hobohm L. A rare case of right heart failure with the necessity for veno-arterial extracorporeal membrane oxygenation following pulmonary vein stenosis after radiofrequency ablation for atrial fibrillation. Pulm Circ. 2023 Feb 21;13(1):e12189

Adenaeuer A, Barco S, Trinchero A, Krutmann S, Nazir HF, Ambaglio C, Rocco V, Pancione Y, Tomao L, Ruiz-Sáez A, Echenagucia M, Alesci S, Sollfrank S, Ezigbo ED, Häuser F, Lackner KJ, Lämmle B, Rossmann H. Severe high-molecular-weight kininogen deficiency: clinical characteristics, deficiency-causing KNG1 variants, and estimated prevalence. J Thromb Haemost. 2023 Feb;21(2):237-254

Keller K, Farmakis IT, Valerio L, Koelmel S, Wild J, Barco S, Schmidt FP, Espinola-Klein C, Konstantinides S, Münzel T, Sagoschen I, Hobohm L. Predisposing factors for admission to intensive care units of patients with COVID-19 infection-Results of the German nationwide inpatient sample. Front Public Health. 2023 Feb 15;11:1113793

Keller K, Schmitt VH, Sagoschen I, Münzel T, Espinola-Klein C, Hobohm L. CRB-65 for Risk Stratification and Prediction of Prognosis in Pulmonary Embolism. J Clin Med. 2023 Feb 5;12(4):1264

Blessing R, Drosos I, Münzel T, Wenzel P, Gori T, Dimitriadis Z. Evaluation of right atrial function by two-dimensional echocardiography and strain imaging in patients with RCA CTO recanalization. BMC Cardiovasc Disord. 2023 Feb 12;23(1):85

Hackenberg B, Döge J, O'Brien K, Bohnert A, Lackner KJ, Beutel ME, Michal M, Münzel T, Wild PS, Pfeiffer N, Schulz A, Schmidtmann I, Matthias C, Bahr K. Tinnitus and Its Relation to Depression, Anxiety, and Stress-A Population-Based Cohort Study. J Clin Med. 2023 Feb 1;12(3):1169

Hahad O, Schmitt VH, Arnold N, Keller K, Prochaska JH, Wild PS, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Schattenberg JM, Tüscher O, Daiber A, Münzel T. Chronic cigarette smoking is associated with increased arterial stiffness in men and women: evidence from a large population-based cohort. Clin Res Cardiol. 2023 Feb;112(2):270-284

Keller K, Schmitt VH, Ostad MA, Münzel T, Hobohm L, Espinola-Klein C. Mansoor's Self-Report Tool for Cardiovascular Risk Assessment predicts adverse in-hospital events in patients with pulmonary embolism. Clin Respir J. 2023 Feb;17(2):80-89

Santiago A, Hann A, Constante M, Rahmani S, Libertucci J, Jackson K, Rueda G, Rossi L, Rithwick R, Ruf W, Schertzer J, Caminero A, Bercik P, Galipeau HJ, Verdu EF. Crohn's disease proteolytic microbiota enhances inflammation through PAR2 pathway in gnotobiotic mice. Gut Microbes. 2023 Jan-Dec;15(1):2205425

Araldi E, Jutzeler CR, Ristow M. Lithium treatment extends human lifespan: findings from the UK Biobank. Aging (Albany NY). 2023 Jan 11;15(2):421-440

Hobohm L, Sagoschen I, Barco S, Farmakis IT, Fedeli U, Koelmel S, Gori T, Espinola-Klein C, Münzel T, Konstantinides S, Keller K. COVID-19 infection and its impact on case fatality in patients with pulmonary embolism. Eur Respir J. 2023 Jan 27;61(1):2200619

Iding AFJ, Kremers BMM, Nagy M, Pallares Robles A, Ten Cate H, Spronk HMH, Ten Cate-Hoek AJ. Translational insights into mechanisms underlying residual venous obstruction and the role of factor XI, P-selectin and GPVI in recurrent venous thromboembolism. Thromb Res. 2023 Jan;221:58-64

Ernst M, Werner AM, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. Posttraumatic growth after childhood cancer: Psychometric evaluation of a five-item short form and associations with mental health. J Psychosom Res. 2023 Jan;164:111099

Farmakis IT, Barco S, Hobohm L, Braekkan SK, Connors JM, Giannakoulas G, Hunt BJ, Keller K, Mavromanoli AC, Trinchero A, Konstantinides SV, Valerio L. Maternal mortality related to pulmonary embolism in the United States, 2003-2020. Am J Obstet Gynecol MFM. 2023 Jan;5(1):100754

Stingl JV, Ban SA, Nagler M, Schmidtmann I, Wild PS, Lackner KJ, Münzel T, Beutel ME, Pfeiffer N, Schuster AK. Five-year change in refractive error and its risk factors: results from the Gutenberg Health Study. Br J Ophthalmol. 2023 Jan;107(1):140-146

Rosenkranz S, Pausch C, Coghlan JG, Huscher D, Pittrow D, Grünig E, Staehler G, Vizza CD, Gall H, Distler O, Delcroix M, Ghofrani HA, Ewert R, Kabitz HJ, Skowasch D, Behr J, Milger K, Halank M, Wilkens H, Seyfarth HJ, Held M, Scelsi L, Neurohr C, Vonk-Noordegraaf A, Ulrich S, Klose H, Claussen M, Eisenmann S, Schmidt KH, Remppis BA, Skride A, Jureviciene E, Gumbiene L, Miliauskas S, Löffler-Ragg J, Lange TJ, Olsson KM, Hoeper MM, Opitz C. Risk stratification and response to therapy in patients with pulmonary arterial hypertension and comorbidities: A COMPERA analysis. J Heart Lung Transplant. 2023 Jan;42(1):102-114

Reviews 2023

Ten Cate V, Prochaska JH, Schulz A, Nagler M, Robles AP, Jurk K, Koeck T, Rapp S, Düber C, Münzel T, Konstantinides SV, Wild PS. Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis. EClinicalMedicine. 2023 Apr 27;59:101973





Krolevets M, Cate VT, Prochaska JH, Schulz A, Rapp S, Tenzer S, Andrade-Navarro MA, Horvath S, Niehrs C, Wild PS. DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Clin Epigenetics. 2023 Mar 30;15(1):56

Buch G, Schulz A, Schmidtmann I, Strauch K, Wild PS. A systematic review and evaluation of statistical methods for group variable selection. Stat Med. 2023 Feb 10;42(3):331-352

Farmakis IT, Keller K, Barco S, Konstantinides SV, Hobohm L. From acute pulmonary embolism to post-pulmonary embolism sequelae. Vasa. 2023 Jan;52(1):29-37

Farmakis IT, Giannakoulas G. Management of COVID-19 in Patients with Pulmonary Arterial Hypertension. Heart Fail Clin. 2023 Jan;19(1):107-114

Mamilos A, Winter L, Schmitt VH, Barsch F, Grevenstein D, Wagner W, Babel M, Keller K, Schmitt C, Gürtler F, Schreml S, Niedermair T, Rupp M, Alt V, Brochhausen C. Macrophages: From Simple Phagocyte to an Integrative Regulatory Cell for Inflammation and Tissue Regeneration-A Review of the Literature. Cells. 2023 Jan 11;12(2):276

Editorials und Fachbeiträge 2023

Nourse J, Danckwardt S. MicroRNAs as prognostic biomarkers for (cancer-associated) venous thromboembolism?". J Thromb Haemost. 2023 Sep;21(9):2634-2637.

Akbulut AC, Arisz RA, Baaten CCFMJ, Baidildinova G, Barakzie A, Bauersachs R, Ten Berg J, van den Broek WWA, de Boer HC, Bonifay A, Bröker V, Buka RJ, Ten Cate H, Ten Cate-Hoek AJ, Cointe S, De Luca C, De Simone I, Diaz RV, Dignat-George F, Freson K, Gazzaniga G, van Gorp ECM, Habibi A, Henskens YMC, Iding AFJ, Khan A, Koenderink GH, Konkoth A, Lacroix R, Lahiri T, Lam W, Lamerton RE, Lorusso R, Luo Q, Maas C, McCarty OJT, van der Meijden PEJ, Meijers JCM, Mohapatra AK, Nevo N, Robles AP, Poncelet P, Reinhardt C, Ruf W, Saraswat R, Schönichen C, Schutgens R, Simioni P, Spada S, Spronk HMH, Tazhibayeva K, Thachil J, Diaz RV, Vallier L, Veninga A, Verhamme P, Visser C, Watson SP, Wenzel P, Willems RAL, Willers A, Zhang P, Zifkos K, van Zonneveld AJ. Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thromb Haemost. 2023 Aug;123(8):808-839.





Subramaniam S, Reinhardt C, Kulkarni PP, Spiezia L. Editorial: COVID-19 and thrombo-inflammatory responses. Front Cardiovasc Med. 2023 Jun 15;10:1231909

Ghanem A, Andrassy M, Duerschmied D, Fuernau G, Geisler T, Hennersdorf M, Knorr M, Lange TJ, Masri-Zada A, Michels G, Rosenkranz S, Schulze PC, Tichelbaecker T, Tiefenbacher C, Wilkens H, Konstantinides S. Interventional treatment and multidisciplinary management strategies for acute pulmonary embolism. KARDIOLOGIE. 2023; 17(3): 141-159

Whyte CS, Panova-Noeva M. Editorial: Women in thrombosis. Front Cardiovasc Med. 2023 Feb 21;10:1159938

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Originalartikel 2022

Méan M, Breakey N, Stalder O, Alberio L, Limacher A, Angelillo-Scherrer A, Fontana P, Beer HJ, Rodondi N, Aujesky D, Lämmle B, Escher R. Thrombophilia and outcomes of venous thromboembolism in older patients. Res Pract Thromb Haemost. 2022 Dec 16;7(1):100015

Haase T, Müller C, Stoffers B, Kirn P, Waldenberger M, Kaiser FJ, Karakas M, Kim SV, Voss S, Wild PS, Lackner KJ, Andersson J, Söderberg S, Lindner D, Zeller T. G Protein-Coupled Receptor 15 Expression Is Associated with Myocardial Infarction. Int J Mol Sci. 2022 Dec 22;24(1):180

Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, Tavares LA, Alves-Rezende ALR, Karbach SH, Nakaya HI, Cunha TM, Souza CS, Cunha FQ, Sales KU, Waisman A, Alves-Filho JC. Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation. Cell Rep. 2022 Dec 27;41(13):111897

Langer F, Gerlach HE, Schimke A, Heinken A, Hoffmann U, Noppeney T, Pittrow D, Klotsche J, Rabe E, Bauersachs R; INSIGHTS-SVT study group. Clinical outcomes of cancer-associated isolated superficial vein thrombosis in daily practice. Thromb Res. 2022 Dec;220:145-152

Hahad O, Beutel ME, Gilan DA, Chalabi J, Schuster AK, Gianicolo E, Lackner KJ, Lieb K, Galle PR, Wild PS, Daiber A, Münzel T. Noise annoyance and risk of prevalent and incident atrial fibrillation-A sex-specific analysis. Front Public Health. 2022 Dec 2;10:1061328

Bonaca MP, Szarek M, Debus ES, Nehler MR, Patel MR, Anand SS, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM. Efficacy and safety of rivaroxaban versus placebo after lower extremity bypass surgery: A post hoc analysis of a "CASPAR like" outcome from VOYAGER PAD. Clin Cardiol. 2022 Dec;45(12):1143-1146

Potere N, Barco S, Mahé I, Cesarman-Maus G, Angchaisuksiri P, Leader A, Okoye HC, Olayemi E, Ay C, Carrier M, Connors JM, Farmakis IT, Fumagalli RM, Jing ZC, Lee LH, McLintock C, Ní Ainle F, Giannakoulas G, Goto S, Guillermo Esposito MC, Jara-Palomares L, Szlaszynska M, Tan CW, Van Es N, Wang TF, Hunt BJ, Di Nisio M. Awareness of venous thromboembolism among patients with cancer: Preliminary findings from a global initiative for World Thrombosis Day. J Thromb Haemost. 2022 Dec;20(12):2964-2971

Sanchez O, Konstantinides SV. Response: Does Fibrinolytic Strategy of Pulmonary Embolism International ThrOmbolysis (PEITHO)-3 Trial Need More Strong Evidence? Thromb Haemost. 2022 Dec;122(12):2052-2053

Lerchbaumer MH, Aviram G, Ebner M, Ritter CO, Steimke L, Rozenbaum Z, Adam SZ, Granot Y, Hasenfuß G, Lotz J, Hamm B, Konstantinides SV, Lankeit M. Optimized definition of right ventricular dysfunction on computed tomography for risk stratification of pulmonary embolism. Eur J Radiol. 2022 Dec;157:110554

Gogiraju R, Renner L, Bochenek ML, Zifkos K, Molitor M, Danckwardt S, Wenzel P, Münzel T, Konstantinides S, Schäfer K. Arginase-1 Deletion in Erythrocytes Promotes Vascular Calcification via Enhanced GSNOR (S-Nitrosoglutathione Reductase) Expression and NO Signaling in Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2022 Dec;42(12):e291-e310.

Wenger N, Sebastian T, Beer JH, Mazzolai L, Aujesky D, Hayoz D, Engelberger RP, Korte W, Voci D, Kucher N, Barco S, Spirk D. Differences in duration of anticoagulation after pulmonary embolism and deep vein thrombosis: Findings from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Thromb Res. 2022 Dec;220:65-71.

Chakrabarty S, Bui Q, Badeanlou L, Hester K, Chun J, Ruf W, Ciaraldi TP, Samad F. S1P/S1PR3 signalling axis protects against obesity-induced metabolic dysfunction. Adipocyte. 2022 Dec;11(1):69-83.

Baidildinova G, Ten Cate V, Nagler M, Panova-Noeva M, Rapp S, Köck T, Prochaska JH, Heitmeier S, Gerdes C, Schwers S, Konstantinides SV, Münzel T, Espinola-Klein C, Lackner KJ, Spronk HMN, Ten Cate H, van der Meijden PEJ, Leineweber K, Wild PS, Jurk K. Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism. Thromb Res. 2022 Dec;220:75-87.

Beckmann L, Mäder J, Voigtlaender M, Klingler F, Schulenkorf A, Lehr C, Regenhardt J, Bokemeyer C, Ruf W, Rolling C, Langer F. Inhibition of protein disulfide isomerase with PACMA-31 regulates monocyte tissue factor through transcriptional and posttranscriptional mechanisms. Thromb Res. 2022 Dec;220:48-59

Fleischer MI, Röhrig N, Raker VK, Springer J, Becker D, Ritz S, Bros M, Stege H, Haist M, Grabbe S, Haub J, Becker C, Reyda S, Disse J, Schmidt T, Mahnke K, Weiler H, Ruf W, Steinbrink K. Protease- and cell type-specific activation of protease-activated receptor 2 in cutaneous inflammation. J Thromb Haemost. 2022 Dec;20(12):2823-2836

Lindhoff-Last E, Birschmann I, Bidenharn AJ, Kuhn J, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, Lucks J, Zydek B, von Heymann C, Sümnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators. Pharmacokinetics of Phenprocoumon in Emergency Situations-Results of the Prospective Observational RADOA-Registry (Reversal Agent Use in Patients Treated with Direct Oral Anticoagulants or Vitamin K Antagonists Registry). Pharmaceuticals (Basel). 2022 Nov 19;15(11):1437

Keller K, Sivanathan V, Schmitt VH, Ostad MA, Münzel T, Espinola-Klein C, Hobohm L. Incidence and impact of venous thromboembolism in hospitalized patients with Crohn's disease. Thromb Res. 2022 Nov;219:77-85

Sagoschen I, Keller K, Wild J, Münzel T, Hobohm L. Case Fatality of Hospitalized Patients with COVID-19 Infection Suffering from Acute Respiratory Distress Syndrome in Germany. Viruses. 2022 Nov 14;14(11):2515

Albertsen IE, Konstantinides SV, Piazza G, Goldhaber SZ, Larsen TB, Søgaard M, Nielsen PB. Risk of Recurrent Venous Thromboembolism in Selected Subgroups of Men: A Danish Nationwide Cohort Study. TH Open. 2022 Nov 18;6(4):e378-e386

Keller K, Sagoschen I, Schmitt VH, Münzel T, Gori T, Hobohm L. Hypothermia and its role in patients with ST-segment-elevation myocardial infarction and cardiac arrest. Front Cardiovasc Med. 2022 Nov 29;9:1051978

Voci D, Götschi A, Held U, Bingisser R, Colucci G, Duerschmied D, Fumagalli RM, Gerber B, Hasse B, Keller DI, Konstantinides SV, Mach F, Rampini SK, Righini M, Robert-Ebadi H, Rosemann T, Roth-Zetzsche S, Sebastian T, Simon NR, Spirk D, Stortecky S, Vaisnora L, Kucher N, Barco S; OVID investigators. Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial. Thromb Res. 2022 Nov 12:S0049-3848(22)00440-6

Konrath S, Mailer RK, Beerens M, Englert H, Frye M, Kuta P, Preston RJS, Maas C, Butler LM, Roest M, de Laat B, Renné T. Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood. Front Cardiovasc Med. 2022 Nov 28;9:1008410

Britto-Borges T, Ludt A, Boileau E, Gjerga E, Marini F, Dieterich C. Magnetique: an interactive web application to explore transcriptome signatures of heart failure. J Transl Med. 2022 Nov 7;20(1):513

Morodomi Y, Kanaji S, Sullivan BM, Zarpellon A, Orje JN, Won E, Shapiro R, Yang XL, Ruf W, Schimmel P, Ruggeri ZM, Kanaji T. Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2212659119

Hasselwander S, Xia N, Mimmler M, Ascher S, Knopp T, Reifenberg G, Karbach S, Ruf W, Reinhardt C, Li H. B lymphocyte-deficiency in mice promotes venous thrombosis. Heliyon. 2022 Nov 17;8(11):e11740

Roewe J, Walachowski S, Sharma A, Berthiaume KA, Reinhardt C, Bosmann M. Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury. Front Immunol. 2022 Nov 3;13:980733. doi: 10.3389/fimmu.2022.980733

Kohls N, Konstantinides SV, Lang IM, Funk GC, Huber K. Risk stratification and risk-adapted management of acute pulmonary embolism. Wien Klin Wochenschr. 2022 Nov 7. doi: 10.1007/s00508-022-02104-0

Farmakis IT, Barco S, Mavromanoli AC, Konstantinides SV, Valerio L. Performance Status and Long-Term Outcomes in Cancer-Associated Pulmonary Embolism: Insights From the Hokusai-VTE Cancer Study. JACC CardioOncol. 2022 Nov 15;4(4):507-518.

Wicke FS, Schmidt P, Petersen J, Ernst M, Krakau L, Brähler E, Tibubos AN, Otten D, Reiner I, Michal M, Schulz A, Münzel T, Wild PS, König J, Lackner KJ, Pfeiffer N, Beutel ME. Depression predicts equivalized income five years later, but not vice versa: Results from the prospective Gutenberg Health Study. Soc Sci Med. 2022 Nov;313:115395.

Kremers BMM, Posma JN, Heitmeier S, Glunz J, Ten Cate H, Pallares Robles A, Daemen JHC, Ten Cate-Hoek AJ, Mees BME, Spronk HMH. Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease. Sci Rep. 2022 Nov 1;12(1):18388.

Ünlü B, Kocatürk B, Rondon AMR, Lewis CS, Swier N, van den Akker RFP, Krijgsman D, Noordhoek I, Blok EJ, Bogdanov VY, Ruf W, Kuppen PJK, Versteeg HH. Integrin regulation by tissue factor promotes cancer stemness and metastatic dissemination in breast cancer. Oncogene. 2022 Nov;41(48):5176-5185.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Lower levels of vWF are associated with lower risk of cardiovascular disease. Res Pract Thromb Haemost. 2022 Nov 6;6(7):e12797.

Gabelmann V, Grabs F, Diestelmeier S, Heindl F, Vosseler M, Münzel T, Sagoschen I, Wild J. Quadrivalvular nonbacterial thrombotic endocarditis in a patient with clear cell cervical cancer. Clin Case Rep. 2022 Oct 17;10(10):e6434

Willems LH, Thijssen DHJ, Groh LA, Kooijman NI, Ten Cate H, Spronk HMH, Donders ART, van der Vijver-Coppen RJ, van Hoek F, Nagy M, Reijnen MMPJ, Warlé MC. Dual pathway inhibition as compared to acetylsalicylic acid monotherapy in relation to endothelial function in peripheral artery disease, a phase IV clinical trial. Front Cardiovasc Med. 2022 Oct 6;9:979819

Baumkötter R, Yilmaz S, Zahn D, Fenzl K, Prochaska JH, Rossmann H, Schmidtmann I, Schuster AK, Beutel ME, Lackner KJ, Münzel T, Wild PS. Protective behavior and SARS-CoV-2 infection risk in the population - Results from the Gutenberg COVID-19 study. BMC Public Health. 2022 Oct 31;22(1):1993.

Pokora RM, Büttner M, Schulz A, Schuster AK, Merzenich H, Teifke A, Michal M, Lackner K, Münzel T, Zeissig SR, Wild PS, Singer S, Wollschläger D. Determinants of mammography screening participation-a cross-sectional analysis of the German population-based Gutenberg Health Study (GHS). PLoS One. 2022 Oct 5;17(10):e0275525.

Schmitt VH, Hobohm L, Vosseler M, Brochhausen C, Münzel T, Espinola-Klein C, Keller K. Temporal trends in patients with peripheral artery disease influenced by diabetes mellitus in Germany. J Diabetes. 2022 Oct;14(10):670-684

Keller K, Schmitt VH, Hobohm LMA, Brochhausen C, Münzel T, Espinola-Klein C. Temporal Trends in Patients with Peripheral Artery Disease Influenced by COVID-19 Pandemic. J Clin Med. 2022 Oct 30;11(21):6433

Pruszczyk P, Klok FA, Kucher N, Roik M, Meneveau N, Sharp ASP, Nielsen-Kudsk JE, Obradović S, Barco S, Giannini F, Stefanini G, Tarantini G, Konstantinides S, Dudek D. Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function and the European Association of Percutaneous Cardiovascular Interventions. EuroIntervention. 2022 Oct 7;18(8):e623-e638

Gogiraju R, Gachkar S, Velmeden D, Bochenek ML, Zifkos K, Hubert A, Münzel T, Offermanns S, Schäfer K. Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. Thromb Haemost. 2022 Oct;122(10):1814-1826

Tarasco E, von Krogh AS, Hrdlickova R, Braschler TR, Iwaniec T, Knöbl PN, Hamada E, Pikovsky O, Farese S, Gutwein O, Kessler P, Schultz NH, von Auer C, Windyga J, Friedman K, Hrachovinova I, George JN, Matsumoto M, Schneppenheim R, Lämmle B, Kremer Hovinga JA. Hereditary thrombotic thrombocytopenic purpura and COVID-19: Impacts of vaccination and infection in this rare disease. Res Pract Thromb Haemost. 2022 Oct 21;6(7):e12814.

Khamis A, Gül D, Wandrey M, Lu Q, Knauer SK, Reinhardt C, Strieth S, Hagemann J, Stauber RH. The Vitamin D Receptor-BIM Axis Overcomes Cisplatin Resistance in Head and Neck Cancer. Cancers (Basel). 2022 Oct 19;14(20):5131

Kalmanti L, Lindhoff-Last E. Bleeding Issues in Women Under Oral Anticoagulation. Hamostaseologie. 2022 Oct;42(5):337-347

Farmakis IT, Barco S, Mavromanoli AC, Agnelli G, Cohen AT, Giannakoulas G, Mahan CE, Konstantinides SV, Valerio L. Cost-of-Illness Analysis of Long-Term Health Care Resource Use and Disease Burden in Patients With Pulmonary Embolism: Insights From the PREFER in VTE Registry. J Am Heart Assoc. 2022 Oct 18;11(20):e027514

Fedeli U, Barbiellini Amidei C, Marcon A, Casotto V, Grippo F, Grande E, Gaisl T, Barco S. Mortality Related to Chronic Obstructive Pulmonary Disease during the COVID-19 Pandemic: An Analysis of Multiple Causes of Death through Different Epidemic Waves in Veneto, Italy. Int J Environ Res Public Health. 2022 Oct 7;19(19):12844.

Kaymaz C, Akbal OY, Keskin B, Tokgoz HC, Hakgor A, Karagoz A, Tanyeri S, Kultursay B, Kulahcioglu S, Dogan C, Bayram Z, Efe SÇ, Erkılınç A, Tanboga IH, Akbulut M, Ozdemir N, Tapson V, Konstantinides S. An Eight-year, Single-center Experience on Ultrasound Assisted Thrombolysis with Moderate-dose, Slow-infusion Regimen in Pulmonary Embolism. Curr Vasc Pharmacol. 2022;20(4):370-378.

Jurk K, Adenaeuer A, Sollfrank S, Groß K, Häuser F, Czwalinna A, Erkel J, Fritsch N, Marandiuc D, Schaller M, Lackner KJ, Rossmann H, Bergmann F. Novel GATA1 Variant Causing a Bleeding Phenotype Associated with Combined Platelet α-/δ-Storage Pool Deficiency and Mild Dyserythropoiesis Modified by a SLC4A1 Variant. Cells. 2022 Sep 29;11(19):3071

Hahad O, Beutel M, Gilan DA, Michal M, Schulz A, Pfeiffer N, König J, Lackner K, Wild P, Daiber A, Münzel T. The association of smoking and smoking cessation with prevalent and incident symptoms of depression, anxiety, and sleep disturbance in the general population.https://pubmed.ncbi.nlm.nih.gov/35777492/ J Affect Disord. 2022 Sep 15;313:100-109

Bell E, Desuki A, Karbach S, Göbel S. Successful treatment of doxorubicin-induced cardiomyopathy with low-dose sacubitril/valsartan: a case report. Eur Heart J Case Rep. 2022 Sep 23;6(10):ytac396

Willems LH, Maas DPMSM, Kramers K, Reijnen MMPJ, Riksen NP, Ten Cate H, van der Vijver-Coppen RJ, de Borst GJ, Mees BME, Zeebregts CJ, Hannink G, Warlé MC. Correction to: Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs. 2022 Sep;82(13):1435.

Kiel M, Grabitz SD, Hopf S, Koeck T, Wild PS, Schmidtmann I, Lackner KJ, Münzel T, Beutel ME, Pfeiffer N, Schuster AK. Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study. J Ophthalmol. 2022 Sep 9;2022:9520512.

Keller K, Geyer M, Hobohm L, Tamm AR, Kreidel F, Ruf TF, Hell M, Schmitt VH, Bachmann K, Born S, Schulz E, Münzel T, von Bardeleben RS. Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal-weight patients. Clin Cardiol. 2022 Sep 7

Wolf S, Spirk D, Forgo G, Sebastian T, Voci D, Kucher N, Barco S. Prevalent use of high-intensity statin therapy and LDL-C target attainment among PAD patients undergoing angioplasty. Vasa. 2022 Sep 2. doi: 10.1024/0301-1526/a001025.

Fumagalli RM, Aimasso U, Valeriani E, Mumoli N, Szlaszynska M, Antonucci E, Palareti G, Mastroiacovo D, Di Nisio M, Barco S. Quality of warfarin anticoagulation in adults with short bowel syndrome on home parenteral nutrition. Vasa. 2022 Sep;51(5):320-322.

Klok FA, Piazza G, Sharp ASP, Ní Ainle F, Jaff MR, Chauhan N, Patel B, Barco S, Goldhaber SZ, Kucher N, Lang IM, Schmidtmann I, Sterling KM, Becker D, Martin N, Rosenfield K, Konstantinides SV. Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: Rationale and design of the HI-PEITHO study. Am Heart J. 2022 Sep;251:43-53.

Fieß A, Stingl J, Urschitz MS, Hoffmann EM, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Birth weight and its association with optic nerve head morphology - results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2022 Sep;100(6):e1349-e1350

Fieß A, Marx-Groß S, Wasielica-Poslednik J, Nagler M, Schmidtmann I, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Peripheral corneal thickness and associated factors - results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2022 Sep;100(6):e1298-e1305.

Pavlaki M, Moiko K, Thomaidis A, Chalikias G, Schäfer K, Konstantinides S, Tziakas D. Modulators of Nitric Oxide-Dependent Osteoinductive Activity of Human Red Blood Cells. TH Open. 2022 Sep 12;6(3):e248-e250.

Farmakis IT, Valerio L, Bikdeli B, Connors JM, Giannakoulas G, Goldhaber SZ, Hobohm L, Hunt BJ, Keller K, Spyropoulos AC, Barco S. Annual mortality related to pulmonary embolism in the US before and during the COVID-19 pandemic. J Am Coll Cardiol. 2022 Aug 12:S0735-1097(22)06535-4.

Keller K, Hartung K, Del Castillo Carillo L, Treiber J, Stock F, Schröder C, Hugenschmidt F, Friedmann-Bette B. Exercise Hypertension in Athletes. J Clin Med. 2022 Aug 19;11(16):4870

Liu X, Wang Y, Bauer AT, Kirschfink M, Ding P, Gebhardt C, Borsig L, Tüting T, Renné T, Häffner K, Hu W, Schneider SW, Gorzelanny C. Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2122716119.

Voigtlaender M, Edler C, Gerling M, Schädler J, Ondruschka B, Schröder AS, Sperhake J, Ehrhardt S, Wang L, Haddad M, Kiencke V, Renné T, Roedl K, Kluge S, Wichmann D, Langer F. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors. Thromb Res. 2022 Aug 28;218:171-176.

Hobohm L, Sagoschen I, Barco S, Farmakis IT, Fedeli U, Koelmel S, Gori T, Espinola-Klein C, Münzel T, Konstantinides S, Keller K. COVID-19 infection and its impact on case-fatality in patients with pulmonary embolism. Eur Respir J. 2022 Aug 18:2200619.

Hu Y, Scharrer A, Hau C, Ay C, Berckmans RJ, Ruf W, Nieuwland R, Thaler J. Coagulation signaling from amniotic fluid to fetal skin. Blood Adv. 2022 Aug 16:bloodadvances.2022007971.

Kreuzpointner R, Johner F, Roth-Zetzsche S, Kucher N, Barco S. Clinical presentation and long-term follow-up of 45 patients with Mondor disease: A single-center longitudinal study. Vasc Med. 2021 Aug;26(4):409-414.

Blessing R, Buono A, Ahoopai M, Geyer M, Knorr M, Brandt M, Steven S, Drosos I, Muenzel T, Wenzel P, Gori T, Dimitriadis Z. Use of intravascular ultrasound for optimal vessel sizing in chronic total occlusion percutaneous coronary intervention. Front Cardiovasc Med. 2022 Aug 3;9:922366.

Shpakova V, Rukoyatkina N, Walter U, Gambaryan S. Potential and limitations of PKA/ PKG inhibitors for platelet studies. Platelets. 2022 Aug 18;33(6):859-868

Rashidi F, Barco S, Rezaeifar P, Sadeghipour P, Ghodrati S, Bakhshandeh H, Mousavi-Aghdas SA, Sadeghi A, Sharifi A, Valizadeh H, Mikaeili H, Rafiee F, Navarbaf Z, Farajian G, Mahmoodpoor A, Bikdeli B, Ansarin K. Tissue plasminogen activator for the treatment of adults with critical COVID-19: A pilot randomized clinical trial. Thromb Res. 2022 Aug;216:125-128.

Göbel S, Hobohm L, Desuki A, Gori T, Münzel T, Claudio R, Wenzel P, Keller K. Impact of cardiac amyloidosis on outcomes of patients hospitalized with heart failure. Eur J Intern Med. 2022 Aug;102:88-96.

Barco S, Voci D, Held U, Sebastian T, Bingisser R, Colucci G, Duerschmied D, Frenk A, Gerber B, Götschi A, Konstantinides SV, Mach F, Robert-Ebadi H, Rosemann T, Simon NR, Spechbach H, Spirk D, Stortecky S, Vaisnora L, Righini M, Kucher N; OVID investigators. Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial. Lancet Haematol. 2022 Aug;9(8):e585-e593.

Pleming W, Barco S, Voci D, Sacco C, Zane F, Granziera S, Corsi G, Konstantinides SV, Kucher N, Pecci A, Valerio L. Cardiac and Cerebral Arterial Complications of Lemierre Syndrome: Results from a Systematic Review and Individual Patient Data Meta-analysis. Hamostaseologie. 2022 Aug;42(4):261-267.

Hogan SE, Nehler MR, Anand S, Patel MR, Debus S, Jackson MT, Buchanan C, King RW, Hess C, Muehlhofer E, Haskell LP, Bauersachs RM, Berkowitz SD, Hsia J, Bonaca MP. Improvement in walking impairment following surgical and endovascular revascularization: Insights from VOYAGER PAD. Vasc Med. 2022 Aug;27(4):343-349.

Adenaeuer A, Barco S, Trinchero A, Lackner KJ, Lämmle B, Rossmann H. Definite diagnosis of plasma prekallikrein deficiency should not be based exclusively on shortening of the aPTT upon prolonged pre-incubation. Int J Lab Hematol. 2022 Aug;44(4):e179-e180.

Brandt M, Dörschmann H, Khraisat S, Knopp T, Ringen J, Kalinovic S, Garlapati V, Siemer S, Molitor M, Göbel S, Stauber R, Helena Karbach S, Münzel T, Daiber A, Wenzel P. Telomere Shortening in Hypertensive Heart Disease Depends on Oxidative DNA Damage and Predicts Impaired Recovery of Cardiac Function in Heart Failure. Hypertension. 2022 Jul 18:101161HYPERTENSIONAHA12118935.

Voci D, Zbinden S, Micieli E, Kucher N, Barco S. Fixed-Dose Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Pulmonary Embolism Associated with COVID-19. Viruses. 2022 Jul 22;14(8):1606.

Krenzlin V, Roewe J, Strueve M, Martínez-Negro M, Sharma A, Reinhardt C, Morsbach S, Bosmann M. Bacterial-Type Long-Chain Polyphosphates Bind Human Proteins in the Phosphatidylinositol Signaling Pathway. Thromb Haemost. 2022 Jul 30. 

Zuin M, Valerio L, Quadretti L, Zuliani G, Manfredini R, Rigatelli G, Barco S, Roncon L. Weekend effect and short-term mortality in patients with acute pulmonary embolism: systematic review and meta-analysis. J Cardiovasc Med (Hagerstown). 2022 Jul 21.

Falanga A, Leader A, Ambaglio C, Bagoly Z, Castaman G, Elalamy I, Lecumberri R, Niessner A, Pabinger I, Szmit S, Trinchero A, Ten Cate H, Rocca B. EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer. Hemasphere. 2022 Jul 13;6(8):e750.

Wild J, Keller K, Karbach S, Weinmann-Menke J, Münzel T, Hobohm L. Case-Fatality and Temporal Trends in Patients with Psoriasis and End-Stage Renal Disease. J Clin Med. 2022 Jul 26;11(15):4328.

Bochenek ML, Gogiraju R, Großmann S, Krug J, Orth J, Reyda S, Georgiadis GS, Spronk HM, Konstantinides S, Münzel T, Griffin JH, Wild P, Espinola-Klein C, Ruf W, Schäfer K. EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia. JCI Insight. 2022 Jul 22;7(14):e157701.

da Costa Marques R, Simon J, d'Arros C, Landfester K, Jurk K, Mailänder V. Proteomics reveals differential adsorption of angiogenic platelet lysate proteins on calcium phosphate bone substitute materials. Regen Biomater. 2022 Jul 5;9:rbac044.

Nagy M, Ten Cate H. What to expect from drug targeting factor XI? Cardiovasc Res. 2022 Jul 27;118(10):e72-e74.

Arnoldussen CWKP, Notten P, Brans R, Vroegindeweij D, Tick LW, van de Poel MHW, Wikkeling ORM, Vleming LJ, Koster A, Jie KG, Jacobs EMG, Planken N, Wittens CHA, Ten Cate H, Wildberger JE, Ten Cate-Hoek AJ. Clinical impact of assessing thrombus age using magnetic resonance venography prior to catheter-directed thrombolysis. Eur Radiol. 2022 Jul;32(7):4555-4564.

Pallares Robles A, Ten Cate V, Schulz A, Prochaska JH, Rapp S, Koeck T, Panova-Noeva M, Heitmeier S, Schwers S, Leineweber K, Seyfarth HJ, Opitz CF, Spronk H, Espinola-Klein C, Lackner KJ, Münzel T, Andrade-Navarro MA, Konstantinides SV, Ten Cate H, Wild PS. Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis. Sci Rep. 2022 Jun 13;12(1):9761.

Zhang L, Dietsche F, Seitaj B, Rojas-Charry L, Latchman N, Tomar D, Wüst RC, Nickel A, Frauenknecht KB, Schoser B, Schumann S, Schmeisser MJ, Vom Berg J, Buch T, Finger S, Wenzel P, Maack C, Elrod JW, Parys JB, Bultynck G, Methner A. TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy.https://pubmed.ncbi.nlm.nih.gov/35715207/ Life Sci Alliance. 2022 Jun 17;5(10):e202201478.

Fieß A, Urschitz MS, Nagler M, Nickels S, Marx-Groß S, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of birth weight with corneal aberrations in adulthood - Results from a population-based study. J Optom. 2022 Jun 25:S1888-4296(21)00054-6.

Yamashita Y, Morimoto T, Klok FA, Barco S, Nishimoto Y, Kato T, Ono K, Kimura T; COMMAND VTE Registry Investigators. Anticoagulation strategies and clinical outcomes after bleeding events during anticoagulation therapy for venous thromboembolism in the practice-based Japanese registry. J Thromb Thrombolysis. 2022 Jun 17.

Willers A, Swol J, van Kuijk SMJ, Buscher H, McQuilten Z, Ten Cate H, Rycus PT, McKellar S, Lorusso R, Tonna JE. HEROES V-A-HEmoRrhagic cOmplications in veno-arterial Extracorporeal life Support-Development and internal validation of a multivariable prediction model in adult patients. Artif Organs. 2022 Jun 16.

Eckelt A, Wichmann F, Bayer F, Eckelt J, Groß J, Opatz T, Jurk K, Reinhardt C, Kiouptsi K. Ethyl Hydroxyethyl Cellulose-A Biocompatible Polymer Carrier in Blood. Int J Mol Sci. 2022 Jun 9;23(12):6432.

Hess CN, Szarek M, Anand SS, Bauersachs RM, Patel MR, Debus ES, Nehler MR, Capell WH, Beckman JA, Piazza G, Henkin S, Bura-Rivière A, Lawall H, Roztocil K, Hsia J, Muehlhofer E, Berkowitz SD, Haskell LP, Bonaca MP. Rivaroxaban and Risk of Venous Thromboembolism in Patients With Symptomatic Peripheral Artery Disease After Lower Extremity Revascularization. JAMA Netw Open. 2022 Jun 1;5(6):e2215580

Hess CN, Baumgartner I, Anand SS, Nehler MR, Patel MR, Debus ES, Szarek M, Capell W, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM, Bonaca MP, Hsia J. Sex-Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD. J Am Heart Assoc. 2022 Jun 21;11(12):e024655.

Otten D, Ernst M, Tibubos AN, Brähler E, Fleischer T, Schomerus G, Wild PS, Zöller D, Binder H, Kruse J, Johar H, Atasoy S, Grabe HJ, Ladwig KH, Münzel T, Völzke H, König J, Beutel ME. Does social support prevent suicidal ideation in women and men? Gender-sensitive analyses of an important protective factor within prospective community cohorts. J Affect Disord. 2022 Jun 1;306:157-166.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background. Thromb J. 2022 Jun 8;20(1):32.

Zhong X, Wang T, Zhang W, Wang M, Xie Y, Dai L, He X, Madhusudhan T, Zeng H, Wang H. ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1. J Biol Chem. 2022 Jun;298(6):101989.

Huber Y, Schulz A, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Galle PR, Wild PS, Lackner KJ, Schattenberg JM. Prevalence and Risk Factors of Advanced Liver Fibrosis in a Population-Based Study in Germany. Hepatol Commun. 2022 Jun;6(6):1457-1466.

Hopf S, Heidt F, Korb CA, Schulz A, Münzel T, Wild PS, Beutel M, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Five-Year Cumulative Incidence and Progression of Myopic Maculopathy in a German Population. Ophthalmology. 2022 May;129(5):562-570.

Mazzolai L, Ageno W, Alatri A, Bauersachs R, Becattini C, Brodmann M, Emmerich J, Konstantinides S, Meyer G, Middeldorp S, Monreal M, Righini M, Aboyans V. Second consensus document on diagnosis and management of acute deep vein thrombosis: updated document elaborated by the ESC Working Group on aorta and peripheral vascular diseases and the ESC Working Group on pulmonary circulation and right ventricular function. Eur J Prev Cardiol. 2022 May 27;29(8):1248-1263.

Berkowitz SD, Bauersachs RM, Szarek M, Nehler MR, Debus ES, Patel MR, Anand SS, Capell WH, Hess CN, Hsia J, Leeper NJ, Brasil D, Mátyás L, Diaz R, Brodmann M, Muehlhofer E, Haskell LP, Bonaca MP. Prevention of arterial and venous thrombotic events in symptomatic peripheral arterial disease patients after lower extremity revascularization in the VOYAGER PAD trial: Dual anticoagulant/antiplatelet regimen vs antiplatelet therapy alone. J Thromb Haemost. 2022 May;20(5):1193-1205

Jurk K. Functional Diversity of Primed Platelets-Powered by Machine Learning. Thromb Haemost. 2022 May;122(5):661.

Valerio L, Fedeli U, Schievano E, Avossa F, Barco S. Decline in Overall Pulmonary Embolism-Related Mortality and Increasing Prevalence of Cancer-Associated Events in the Veneto Region (Italy), 2008-2019. Thromb Haemost. 2022 May;122(5):789-795.

Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2022 May;179(10):2086-2099.

Sanchez O, Charles-Nelson A, Ageno W, Barco S, Binder H, Chatellier G, Duerschmied D, Empen K, Ferreira M, Girard P, Huisman MV, Jiménez D, Katsahian S, Kozak M, Lankeit M, Meneveau N, Pruszczyk P, Petris A, Righini M, Rosenkranz S, Schellong S, Stefanovic B, Verhamme P, de Wit K, Vicaut E, Zirlik A, Konstantinides SV, Meyer G; PEITHO-3 Investigators. Reduced-Dose Intravenous Thrombolysis for Acute Intermediate-High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial. Thromb Haemost. 2022 May;122(5):857-866.

Chaudhary N, Jayaraman A, Reinhardt C, Campbell JD, Bosmann M. A single-cell lung atlas of complement genes identifies the mesothelium and epithelium as prominent sources of extrahepatic complement proteins. Mucosal Immunol. 2022 May;15(5):927-939.

Willers A, Swol J, van Kuijk SMJ, Buscher H, McQuilten Z, Ten Cate H, Rycus PT, McKellar S, Lorusso R, Tonna JE. HEROES V-V-HEmorRhagic cOmplications in Veno-Venous Extracorporeal life Support-Development and internal validation of multivariable prediction model in adult patients. Artif Organs. 2022 May;46(5):932-952.

Gehrke N, Wörns MA, Mann A, Hövelmeyer N, Waisman A, Straub BK, Galle PR, Schattenberg JM. Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure. Cell Death Dis. 2022 May 31;13(5):510.

Keller K, Sagoschen I, Schmitt VH, Sivanathan V, Espinola-Klein C, Lavie CJ, Münzel T, Hobohm L. Obesity and Its Impact on Adverse In-Hospital Outcomes in Hospitalized Patients With COVID-19. Front Endocrinol (Lausanne). 2022 May 2;13:876028

Keller K, Prochaska JH, Coldewey M, Göbel S, Schmitt VH, Hahad O, Ullmann A, Nagler M, Lamparter H, Espinola-Klein C, Münzel T, Wild PS. Atherosclerosis and Its Impact on the Outcomes of Patients with Deep Venous Thrombosis. Life (Basel). 2022 May 14;12(5):734.

Neuenschwander J, Sebastian T, Barco S, Spirk D, Kucher N. A novel management strategy for treatment of pelvic venous disorders utilizing a clinical screening score and non-invasive imaging. Vasa. 2022 May;51(3):182-189.

Pfeilschifter W, Lindhoff-Last E, Alhashim A, Zydek B, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, von Heymann C, Birschmann I, Beyer-Westendorf J, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators (Reversal Agent use in patients treated with Direct Oral Anticoagulants or vitamin K antagonists Registry). Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry. Neurol Res Pract. 2022 May 2;4(1):16.

Wild J, Ringen J, Bieler T, Knopp T, Lagrange J, Molitor M, Sies K, Kropp A, Keller K, Daiber A, Münzel T, Rauh M, Waisman A, Wenzel P, Titze J, Karbach S. Epicutaneous Application of Imiquimod to Model Psoriasis-Like Skin Disease Induces Water-Saving Aestivation Motifs and Vascular Inflammation. J Invest Dermatol. 2022 May 14:S0022-202X(22)00392-X

Greinacher A, Langer F, Schonborn L, Thiele T, Haddad M, Renne T, Rollin J, Gruel Y, Warkentin TE. Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy. Haematologica. 2022 May 1;107(5):1219-1221.

Jurk K, Rothenaicher KF, Groß K, Rossmann H, Weißer G, Schmidtmann I, Münzel T, Espinola-Klein C. Differential Inhibition of Platelet Reactivity by Dual Therapy With Aspirin and Low-Dose Rivaroxaban in Peripheral Arterial Disease: A Pilot Study. Front Cardiovasc Med. 2022 May 6;9:865166.

Sharma A, Noon JB, Kontodimas K, Garo LP, Platten J, Quinton LJ, Urban JF Jr, Reinhardt C, Bosmann M. IL-27 Enhances γδ T Cell-Mediated Innate Resistance to Primary Hookworm Infection in the Lungs. J Immunol. 2022 Apr 15;208(8):2008-2018

Mora D, Nieto JA, Mateo J, Bikdeli B, Barco S, Trujillo-Santos J, Soler S, Font L, Bosevski M, Monreal M; RIETE Investigators. Machine Learning to Predict Outcomes in Patients with Acute Pulmonary Embolism Who Prematurely Discontinued Anticoagulant Therapy. Thromb Haemost. 2022 Apr;122(4):570-577.

Wicke FS, Ernst M, Otten D, Werner A, Dreier M, Brähler E, Tibubos AN, Reiner I, Michal M, Wiltink J, Münzel T, Lackner KJ, Pfeiffer N, König J, Wild PS, Beutel ME. The association of depression and all-cause mortality: Explanatory factors and the influence of gender. J Affect Disord. 2022 Apr 15;303:315-322.

Otten D, Ernst M, Werner AM, Tibubos AN, Reiner I, Brähler E, Wiltink J, Michal M, Nagler M, Wild PS, Münzel T, König J, Lackner KJ, Peiffer N, Beutel ME. Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample. Psychol Med. 2022 Apr 21:1-9.

Spirk D, Sebastian T, Beer JH, Mazzolai L, Aujesky D, Hayoz D, Engelberger RP, Korte W, Kucher N, Barco S. Role of age, sex, and specific provoking factors on the distal versus proximal presentation of first symptomatic deep vein thrombosis: analysis of the SWIss Venous ThromboEmbolism Registry (SWIVTER). Intern Emerg Med. 2022 Apr;17(3):799-803.

Leberzammer J, Agten SM, Blanchet X, Duan R, Ippel H, Megens RTA, Schulz C, Aslani M, Duchene J, Döring Y, Jooss NJ, Zhang P, Brandl R, Stark K, Siess W, Jurk K, Heemskerk JWM, Hackeng TM, Mayo KH, Weber C, von Hundelshausen P. Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood. 2022 Apr 28;139(17):2691-2705.

Lammle B. A third form of thrombotic thrombocytopenic purpura? Haematologica. 2022 Apr 28

Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19;39(3):110714.

Schmitt VH, Hobohm L, Sivanathan V, Brochhausen C, Gori T, Münzel T, Konstantinides SV, Keller K. Diabetes mellitus and its impact on mortality rate and outcome in pulmonary embolism.https://pubmed.ncbi.nlm.nih.gov/34779148/ J Diabetes Investig. 2022 Apr;13(4):725-737

Hess CN, Capell WH, Bristow MR, Ruf W, Szarek M, Morrow DA, Nicolau JC, Graybill CA, Marshall D, Hsia J, Bonaca MP. Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial. Am Heart J. 2022 Apr;246:136-143

Schmitt VH, Hobohm L, Sivanathan V, Brochhausen C, Gori T, Münzel T, Konstantinides SV, Keller K. Diabetes mellitus and its impact on mortality rate and outcome in pulmonary embolism. J Diabetes Investig. 2022 Apr;13(4):725-737.

Douglas RS, Kahaly GJ, Ugradar S, Elflein H, Ponto KA, Fowler BT, Dailey R, Harris GJ, Schiffman J, Tang R, Wester S, Jain AP, Marcocci C, Marinò M, Antonelli A, Eckstein A, Führer-Sakel D, Salvi M, Sile S, Francis-Sedlak M, Holt RJ, Smith TJ. Teprotumumab Efficacy, Safety, and Durability in Longer-Duration Thyroid Eye Disease and Re-treatment: OPTIC-X Study. Ophthalmology. 2022 Apr;129(4):438-449.

Mauschitz MM, Schmitz MT, Verzijden T, Schmid M, Thee EF, Colijn JM, Delcourt C, Cougnard-Grégoire A, Merle BMJ, Korobelnik JF, Gopinath B, Mitchell P, Elbaz H, Schuster AK, Wild PS, Brandl C, Stark KJ, Heid IM, Günther F, Peters A, Klaver CCW, Finger RP; European Eye Epidemiology (E3) Consortium. Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study. Am J Ophthalmol. 2022 Apr;236:99-106.

Voci D, Fedeli U, Farmakis IT, Hobohm L, Keller K, Valerio L, Schievano E, Barbiellini Amidei C, Konstantinides SV, Kucher N, Barco S. Deaths related to pulmonary embolism and cardiovascular events before and during the 2020 COVID-19 pandemic: An epidemiological analysis of data from an Italian high-risk area. Thromb Res. 2022 Apr;212:44-50.

Masoodi M, Peschka M, Schmiedel S, Haddad M, Frye M, Maas C, Lohse A, Huber S, Kirchhof P, Nofer JR, Renné T. Disturbed lipid and amino acid metabolisms in COVID-19 patients. J Mol Med (Berl). 2022 Apr;100(4):555-568.

Valerio L, Mavromanoli AC, Barco S, Abele C, Becker D, Bruch L, Ewert R, Faehling M, Fistera D, Gerhardt F, Ghofrani HA, Grgic A, Grünig E, Halank M, Held M, Hobohm L, Hoeper MM, Klok FA, Lankeit M, Leuchte HH, Martin N, Mayer E, Meyer FJ, Neurohr C, Opitz C, Schmidt KH, Seyfarth HJ, Wachter R, Wilkens H, Wild PS, Konstantinides SV, Rosenkranz S; FOCUS Investigators. Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study. Eur Heart J. 2022 Apr 28:ehac206.

Halfmann MC, Benz S, Schoepf UJ, Düber C, Kloeckner R, Eichstaedt J, Wenzel P, Kreitner KF, Varga-Szemes A, Emrich T. Myocardial Mass Corrected CMR Feature Tracking-Based Strain Ratios are Different in Pathologies With Increased Myocardial Mass. Acad Radiol. 2022 Apr;29 Suppl 4:S40-S48.

Lindhoff-Last E, Birschmann I, Kuhn J, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, Lucks J, Zydek B, von Heymann C, Sümnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators (Reversal Agent use in patients treated with Direct Oral Anticoagulants or vitamin K antagonists Registry). Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry. Thromb Haemost. 2022 Apr;122(4):552-559.

Ludt A, Ustjanzew A, Binder H, Strauch K, Marini F. Interactive and Reproducible Workflows for Exploring and Modeling RNA-seq Data with pcaExplorer, Ideal, and GeneTonic. Curr Protoc. 2022 Apr;2(4):e411.

Petersen EL, Goßling A, Adam G, Aepfelbacher M, Behrendt CA, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber TB, Kluge S, Knobloch JK, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele FL, Petersen M, Renné T, Riedl KA, Rimmele DL, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel JP, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S. Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. Eur Heart J. 2022 Mar 14;43(11):1124-1137.

Ernst M, Brähler E, Faber J, Wild PS, Merzenich H, Beutel ME. A Mixed-Methods Investigation of Medical Follow-Up in Long-Term Childhood Cancer Survivors: What Are the Reasons for Non-Attendance? Front Psychol. 2022 Mar 14;13:846671.

Micieli E, Voci D, Mumoli N, Mastroiacovo D, Grigorean A, Obadia M, de Champfleur NM, Naggara O, Carsin B, Amor-Sahli M, Cottier JP, Bensoussan J, Auffray-Calvier E, Varoquaux A, Bonneville F, Sadik JC, Kucher N, Lecler A, Barco S. Transient perivascular inflammation of the carotid artery (TIPIC) syndrome. Vasa. 2022 Mar;51(2):71-77.

Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 Mar 17;90(3):e0049121

Pohl KR, Hobohm L, Krieg VJ, Sentler C, Rogge NIJ, Steimke L, Ebner M, Lerchbaumer M, Hasenfuß G, Konstantinides S, Lankeit M, Keller K. Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism. Thromb Res. 2022 Mar;211:70-78.

Mooz J, Riegel K, Ps H, Sadanandam A, Marini F, Klein M, Werner U, Roth W, Wilken-Schmitz A, Tegeder I, Rajalingam K. ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers. Sci Adv. 2022 Mar 18;8(11):eabk1538

Keller K, Hobohm L, Münzel T, Lankeit M, Konstantinides S, Ostad MA. Impact of Systemic Atherosclerosis on Clinical Characteristics and Short-Term Outcomes in Patients with Deep Venous Thrombosis or Thrombophlebitis. Am J Med Sci. 2022 Mar;363(3):232-241.

Lüscher TF, Davies A, Beer JH, Valgimigli M, Nienaber CA, Camm JA, Baumgartner I, Diener HC, Konstantinides SV. Towards personalized antithrombotic management with drugs and devices across the cardiovascular spectrum. Eur Heart J. 2022 Mar 7;43(10):940-958

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535

Schmitt VH, Leuschner A, Jünger C, Pinto A, Hahad O, Schulz A, Arnold N, Tröbs SO, Panova-Noeva M, Keller K, Zeller T, Beutel M, Pfeiffer N, Strauch K, Blankenberg S, Lackner KJ, Prochaska JH, Wild PS, Münzel T. Cardiovascular profiling in the diabetic continuum: results from the population-based Gutenberg Health Study. Clin Res Cardiol. 2022 Mar;111(3):272-283.

Jünger C, Prochaska JH, Gori T, Schulz A, Binder H, Daiber A, Koeck T, Rapp S, Lackner KJ, Münzel T, Wild PS. Rationale and design of the effects of EMpagliflozin on left ventricular DIAstolic function in diabetes (EmDia) study. J Cardiovasc Med (Hagerstown). 2022 Mar 1;23(3):191-197.

Panova-Noeva M, Wagner B, Nagler M, Koeck T, Ten Cate V, Eggebrecht L, Prochaska JH, Meyer I, Gerdes C, Spronk HM, Lackner KJ, Ten Cate H, Leineweber K, Heitmeier S, Konstantinides S, Wild PS. Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project. J Thromb Haemost. 2022 Mar;20(3):705-715.

Eichstaedt CA, Saßmannshausen Z, Shaukat M, Cao D, Xanthouli P, Gall H, Sommer N, Ghofrani HA, Seyfarth HJ, Lerche M, Halank M, Kleymann J, Benjamin N, Harutyunova S, Egenlauf B, Milger K, Rosenkranz S, Ewert R, Klose H, Hoeper MM, Olsson KM, Lankeit M, Lange TJ, Hinderhofer K, Grünig E. Gene panel diagnostics reveals new pathogenic variants in pulmonary arterial hypertension. Respir Res. 2022 Mar 27;23(1):74.

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535.

Wild J, Siegrist B, Hobohm L, Münzel T, Schwanz T, Sagoschen I. Short and Concise Peer-to-Peer Teaching-Example of a Successful Antibiotic Stewardship Intervention to Increase Iv to Po Conversion. Antibiotics (Basel). 2022 Mar 17;11(3):402.

Stamm P, Kalinovic S, Oelze M, Steven S, Czarnowski A, Kvandova M, Bayer F, Reinhardt C, Münzel T, Daiber A. Mechanistic Insights into Inorganic Nitrite-Mediated Vasodilation of Isolated Aortic Rings under Oxidative/Hypertensive Conditions and S-Nitros(yl)ation of Proteins in Germ-Free Mice. Biomedicines. 2022 Mar 21;10(3):730.

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535.

Wallis S, Wolska N, Englert H, Posner M, Upadhyay A, Renné T, Eggleston I, Bagby S, Pula G. A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes. J Thromb Haemost. 2022 Mar;20(3):729-741.

Wendelboe AM, Langenfeld H, Ageno W, Castellucci L, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Forgo G, Guillermo Esposito MC, McLintock C, Ní Áinle F, Spyropoulos AC, Urano T, Barco S, Hunt BJ. Current practices of standardized risk assessment for venous thromboembolism: Results from a global survey from the World Thrombosis Day steering committee. J Thromb Haemost. 2022 Feb;20(2):532-535.

Arnold N, Hermanns IM, Schulz A, Hahad O, Schmitt VH, Panova-Noeva M, Prochaska JH, Binder H, Pfeiffer N, Beutel M, Lackner KJ, Münzel T, Wild PS. Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population. Cardiovasc Res. 2022 Feb 23:cvac019.

Sanrattana W, Smits S, Barendrecht AD, van Kleef ND, El Otmani H, Zivkovic M, Roest M, Renné T, Clark CC, de Maat S, Maas C. Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery. J Thromb Haemost. 2022 Feb;20(2):353-365.

Kreuzpointner R, Valerio L, Corsi G, Zane F, Sacco C, Holm K, Righini C, Pecci A, Zweifel S, Barco S. Ophthalmic complications of Lemierre syndrome. Acta Ophthalmol. 2022 Feb;100(1):e314-e320.

Shahneh F, Christian Probst H, Wiesmann SC, A-Gonzalez N, Ruf W, Steinbrink K, Raker VK, Becker C. Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and Resolution. Arterioscler Thromb Vasc Biol. 2022 Feb;42(2):145-155.

Schnabel RB, Magnussen C, Schulz A, Ojeda FM, Schmitt VH, Arnold N, Sinning CR, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Lackner KJ, Gori T, Benjamin EJ, Binder H, Wild PS, Blankenberg S, Münzel T; Gutenberg Health Study investigators. Non-invasive peripheral vascular function, incident cardiovascular disease, and mortality in the general population. Cardiovasc Res. 2022 Feb 21;118(3):904-912.

Blessing RRL, Ahoopai M, Geyer M, Brandt M, Zeiher AM, Vasa-Nicotera M, Münzel T, Wenzel P, Gori T, Dimitriadis Z. Percutaneous coronary intervention for chronic total occlusion in octogenarians: a propensity score study. Sci Rep. 2022 Feb 23;12(1):3073.

Hrdinova J, Fernández DI, Ercig B, Tullemans BME, Suylen DPL, Agten SM, Jurk K, Hackeng TM, Vanhoorelbeke K, Voorberg J, Reutelingsperger CPM, Wichapong K, Heemskerk JWM, Nicolaes GAF. Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. Int J Mol Sci. 2022 Feb 12;23(4):2046.

Forgo G, Micieli E, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Guillermo Esposito MC, Konstantinides SV, Kucher N, McLintock C, Ní Áinle F, Spyropoulos AC, Urano T, Hunt BJ, Barco S. An update on the global use of risk assessment models and thromboprophylaxis in hospitalized patients with medical illnesses from the World Thrombosis Day steering committee: Systematic review and meta-analysis. J Thromb Haemost. 2022 Feb;20(2):409-421.

Kouz K, Bergholz A, Diener O, Leistenschneider M, Thompson C, Pichotka F, Trepte C, Schwedhelm E, Renné T, Krause L, Nicklas JY, Saugel B. Effect of intraoperative personalized goal-directed hemodynamic management on acute myocardial injury in high-risk patients having major abdominal surgery: a post-hoc secondary analysis of a randomized clinical trial. J Clin Monit Comput. 2022 Feb 24.

Wegner J, Karbach S, Drosos I, Schnorbus B, Muxel S, Schmidt F, Wenzel P, Waisman A, Münzel T, Gori T, von Stebut E. TNF-α blockade may lead to improvement of vascular function in psoriasis patients. Exp Dermatol. 2022 Feb;31(2):237-241.

Efentakis P, Molitor M, Kossmann S, Bochenek ML, Wild J, Lagrange J, Finger S, Jung R, Karbach S, Schäfer K, Schulz A, Wild P, Münzel T, Wenzel P. Tubulin-folding cofactor E deficiency promotes vascular dysfunction by increased endoplasmic reticulum stress. Eur Heart J. 2022 Feb 10;43(6):488-500.

Willems LH, Nagy M, Ten Cate H, Spronk HMH, Groh LA, Leentjens J, Janssen NAF, Netea MG, Thijssen DHJ, Hannink G, van Petersen AS, Warlé MC. Sustained inflammation, coagulation activation and elevated endothelin-1 levels without macrovascular dysfunction at 3 months after COVID-19. Thromb Res. 2022 Jan;209:106-114.

Nuebling M, Hegewald J, Starke KR, Lincke HJ, Jankowiak S, Liebers F, Latza U, Letzel S, Riechmann-Wolf M, Gianicolo E, Beutel M, Pfeiffer N, Lackner K, Münzel T, Wild PS, Seidler A. The Gutenberg health study: a five-year prospective analysis of psychosocial working conditions using COPSOQ (Copenhagen psychosocial Questoinnaire) and ERI (effort-reward imbalance). BMC Public Health. 2022 Jan 6;22(1):24.

Zhang W, Wang M, Gao K, Zhong X, Xie Y, Dai L, Liu W, Liu Y, He X, Li S, Madhusudhan T, Wang H, Zeng H. Pharmacologic IRE1α kinase inhibition alleviates aortic dissection by decreasing vascular smooth muscle cells apoptosis. Int J Biol Sci. 2022 Jan 1;18(3):1053-1064.

Hobohm L, Sagoschen I, Barco S, Schmidtmann I, Espinola-Klein C, Konstantinides S, Münzel T, Keller K. Trends and Risk Factors of In-Hospital Mortality of Patients with COVID-19 in Germany: Results of a Large Nationwide Inpatient Sample. Viruses. 2022 Jan 28;14(2):275

Wiedenroth CB, Bandorski D, Ariobi K, Ghofrani HA, Lankeit M, Liebetrau C, Pruefer D, Mayer E, Kriechbaum SD, Guth S. Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH. Thorac Cardiovasc Surg. 2022 Jan 17.

Hoffmann EM, Aghayeva F, Wagner FM, Fiess A, Nagler M, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):40.

Frenis K, Kalinovic S, Ernst BP, Kvandova M, Al Zuabi A, Kuntic M, Oelze M, Stamm P, Bayo Jimenez MT, Kij A, Keppeler K, Klein V, Strohm L, Ubbens H, Daub S, Hahad O, Kröller-Schön S, Schmeisser MJ, Chlopicki S, Eckrich J, Strieth S, Daiber A, Steven S, Münzel T. Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development. Front Mol Biosci. 2022 Jan 31;8:814921.

Heidorn MW, Steck S, Müller F, Tröbs SO, Buch G, Schulz A, Schwuchow-Thonke S, Schuch A, Strauch K, Schmidtmann I, Lackner KJ, Gori T, Münzel T, Wild PS, Prochaska JH. FEV₁ Predicts Cardiac Status and Outcome in Chronic Heart Failure. Chest. 2022 Jan;161(1):179-189.

Zuin M, Engelen MM, Barco S, Spyropoulos AC, Vanassche T, Hunt BJ, Vandenbriele C, Verhamme P, Kucher N, Rashidi F, Zuliani G, Konstantinides SV, Roncon L. Incidence of venous thromboembolic events in COVID-19 patients after hospital discharge: A systematic review and meta-analysis. Thromb Res. 2022 Jan;209:94-98.

Turatti G, Fedeli U, Valerio L, Klok FA, Cohen AT, Hunt BJ, Simioni P, Middeldorp S, Ageno W, Kucher N, Konstantinides SV, Schievano E, Barco S. Splanchnic vein thrombosis-related mortality in the Veneto region (Italy), 2008-2019: Retrospective analysis of epidemiological data. Thromb Res. 2022 Jan;209:41-46.

Maifeld A, Wild J, Karlsen TV, Rakova N, Wistorf E, Linz P, Jung R, Birukov A, Gimenez-Rivera VA, Wilck N, Bartolomaeus T, Dechend R, Kleinewietfeld M, Forslund SK, Krause A, Kokolakis G, Philipp S, Clausen BE, Brand A, Waisman A, Kurschus FC, Wegner J, Schultheis M, Luft FC, Boschmann M, Kelm M, Wiig H, Kuehne T, Müller DN, Karbach S, Markó L. Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. J Invest Dermatol. 2022 Jan;142(1):166-178.e8.

Hobohm L, Sagoschen I, Habertheuer A, Barco S, Valerio L, Wild J, Schmidt FP, Gori T, Münzel T, Konstantinides S, Keller K. Clinical use and outcome of extracorporeal membrane oxygenation in patients with pulmonary embolism. Resuscitation. 2022 Jan;170:285-292.

Merzenich H, Baaken D, Schneider A, Neu MA, Wingerter A, Faber J, Wild PS, Spix C. Mortality risk among 5-year survivors of childhood cancer in Germany-Results from the CVSS study (Cardiac and Vascular late Sequelae in long-term Survivors of childhood cancer study). Int J Cancer. 2022 Jan 1;150(1):67-72.

Klok FA, Ageno W, Ay C, Bäck M, Barco S, Bertoletti L, Becattini C, Carlsen J, Delcroix M, van Es N, Huisman MV, Jara-Palomares L, Konstantinides S, Lang I, Meyer G, Ní Áinle F, Rosenkranz S, Pruszczyk P. Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society. Eur Heart J. 2022 Jan 25;43(3):183-189.

Korb CA, Elbaz H, Schuster AK, Nickels S, Ponto KA, Schulz A, Wild PS, Münzel T, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N. Five-year cumulative incidence and progression of age-related macular degeneration: results from the German population-based Gutenberg Health Study (GHS). Graefes Arch Clin Exp Ophthalmol. 2022 Jan;260(1):55-64.

Reviews 2022

Subramaniam S, Kothari H, Bosmann M. Tissue factor in COVID-19-associated coagulopathy. Thromb Res. 2022 Dec;220:35-47.

Khan ES, Danckwardt S. Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond. Genes (Basel). 2022 Nov 22;13(12):2181

Wauthier L, Favresse J, Hardy M, Douxfils J, Le Gal G, Roy PM, van Es N, Ay C, Ten Cate H, Vander Borght T, Dupont MV, Lecompte T, Lippi G, Mullier F. D-dimer Testing in Pulmonary Embolism with a Focus on Potential Pitfalls: A Narrative Review. Diagnostics (Basel). 2022 Nov 12;12(11):2770

Nagy M, van der Meijden PEJ, Glunz J, Schurgers L, Lutgens E, Ten Cate H, Heitmeier S, Spronk HMH. Integrating Mechanisms in Thrombotic Peripheral Arterial Disease. https://pubmed.ncbi.nlm.nih.gov/36422558/Pharmaceuticals (Basel). 2022 Nov 18;15(11):1428



Gwozdz AM, de Jong CMM, Fialho LS, Likitabhorn T, Sossi F, Jaber PB, Højen AA, Arcelus JI, Auger WR, Ay C, Barco S, Gazzana MB, Bayley J, Bertoletti L, Cate-Hoek AT, Cohen AT, Connors JM, Galanaud JP, Labropoulos N, Langlois N, Meissner MH, Noble S, Nossent EJ, de León Lovatón PP, Robert-Ebadi H, Rosovsky RP, Smolenaars N, Toshner M, Tromeur C, Wang KL, Westerlund E, de Wit K, Black SA, Klok FA. Development of an international standard set of outcome measures for patients with venous thromboembolism: an International Consortium for Health Outcomes Measurement consensus recommendation. Lancet Haematol. 2022 Sep;9(9):e698-e706.

Hobohm L, Farmakis IT, Keller K, Scibior B, Mavromanoli AC, Sagoschen I, Münzel T, Ahrens I, Konstantinides S. Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis. Clin Res Cardiol. 2022 Aug 17:1–11.

Willems LH, Maas DPMSM, Kramers K, Reijnen MMPJ, Riksen NP, Ten Cate H, van der Vijver-Coppen RJ, de Borst GJ, Mees BME, Zeebregts CJ, Hannink G, Warlé MC. Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs. 2022 Aug 23.

Gorog DA, Storey RF, Gurbel PA, Tantry US, Berger JS, Chan MY, Duerschmied D, Smyth SS, Parker WAE, Ajjan RA, Vilahur G, Badimon L, Berg JMT, Cate HT, Peyvandi F, Wang TT, Becker RC. Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium. Nat Rev Cardiol. 2022 Jul;19(7):475-495

Mast AE, Ruf W. Regulation of coagulation by tissue factor pathway inhibitor: Implications for hemophilia therapy. J Thromb Haemost. 2022 Jun;20(6):1290-1300

Task Force for the management of COVID-19 of the European Society of Cardiology. ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2-care pathways, treatment, and follow-up. Cardiovasc Res. 2022 Jun 22;118(7):1618-1666.

Zwirner J, Kulakofsky R, Fitzek A, Schröder AS, Bohnert S, Franke H, Renné T, Tse R, Ondruschka B. Forensic biomarkers of lethal traumatic brain injury. Int J Legal Med. 2022 May;136(3):871-886.

Paeslack N, Mimmler M, Becker S, Gao Z, Khuu MP, Mann A, Malinarich F, Regen T, Reinhardt C. Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease. Amino Acids. 2022 Apr 22.

Spada S, Luke B, Danckwardt S. The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Front Genet. 2022 Apr 28;13:854907

Mendelsohn DH, Schnabel K, Mamilos A, Sossalla S, Pabel S, Duerr GD, Keller K, Schmitt VH, Barsch F, Walter N, Wong RMY, El Khassawna T, Niedermair T, Alt V, Rupp M, Brochhausen C. Structural Analysis of Mitochondrial Dynamics-From Cardiomyocytes to Osteoblasts: A Critical Review. Int J Mol Sci. 2022 Apr 20;23(9):4571

Wang H, Karnati S, Madhusudhan T. Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy. Pharmaceuticals (Basel). 2022 Mar 25;15(4):401.

Mandel J, Casari M, Stepanyan M, Martyanov A, Deppermann C. Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation. https://pubmed.ncbi.nlm.nih.gov/35409226/Int J Mol Sci. 2022 Mar 31;23(7):3868.

Hobohm L, Farmakis IT, Münzel T, Konstantinides S, Keller K. Pulmonary Embolism and Pregnancy-Challenges in Diagnostic and Therapeutic Decisions in High-Risk Patients. Front Cardiovasc Med. 2022 Mar 8;9:856594.

Dauwerse S, Ten Cate H, Spronk HMH, Nagy M. The Composition and Physical Properties of Clots in COVID-19 Pathology. Diagnostics (Basel). 2022 Feb 24;12(3):580

Helmstädter J, Keppeler K, Küster L, Münzel T, Daiber A, Steven S. Glucagon-like peptide-1 (GLP-1) receptor agonists and their cardiovascular benefits-The role of the GLP-1 receptor. Br J Pharmacol. 2022 Feb;179(4):659-676.

Mailer RK, Kuta P, Renné T. An Update on Safe Anticoagulation. Hamostaseologie. 2022 Feb;42(1):65-72

Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. An update on factor XII-driven vascular inflammation. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.

Klok FA, Pai M, Huisman MV, Makris M. Vaccine-induced immune thrombotic thrombocytopenia. Lancet Haematol. 2022 Jan;9(1):e73-e80

Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. An update on factor XII-driven vascular inflammation. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.

Editorials und Fachbeiträge 2022

Barco S, Schreiber K. COVID-19: ACT trials for colchicine and antithrombotic therapies. Lancet Respir Med. 2022 Dec;10(12):1106-1108

Luo Q, Wenzel P. Properdin (factor P) as a new target cleaved by factor XIa: Intrinsic coagulation at the crossroads with inflammation. Res Pract Thromb Haemost. 2022 Nov 4;6(7):e12835

Wenzel P. Thromboinflammation in cardiovascular disease: lessons learned for the management of hypertension, heart failure, and aortic valve stenosis. Eur Heart J. 2022 Nov 21;43(44):4611-4613

Gorog DA, Gue YX, Chao TF, Fauchier L, Ferreiro JL, Huber K, Konstantinidis SV, Lane DA, Marin F, Oldgren J, Potpara T, Roldan V, Rubboli A, Sibbing D, Tse HF, Vilahur G, Lip GYH. Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute CardioVascular Care and the Asia-Pacific Heart Rhythm Society. Europace. 2022 Nov 22;24(11):1844-1871

Adenaeuer A, Barco S, Trinchero A, Lackner KJ, Lämmle B, Rossmann H. Definite diagnosis of plasma prekallikrein deficiency should not be based exclusively on shortening of the aPTT upon prolonged pre-incubation. Int J Lab Hematol. 2022 Aug;44(4):e179-e180

Haghikia A, van Mens TE, Pontarollo G, Reinhardt C. Editorial: Impact of the gut microbiota on cardiovascular medicine. Front Med (Lausanne). 2022 Jul 13;9:939890.

Mailer RK, Renné T. Commentary on "Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa": Small molecule factor XIa inhibitor asundexian allows for safer anticoagulation. J Thromb Haemost. 2022 Jun;20(6):1309-1311

Koizume S, Kobayashi S, Ruf W, Miyagi Y. Authors' reply to the Letter to the Editor: Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer. Cancer Sci. 2022 May;113(5):1888-1890.

Anand SS, Hiatt W, Dyal L, Bauersachs R, Berkowitz SD, Branch KRH, Debus S, Fox KAA, Liang Y, Muehlhofer E, Nehler M, Haskell LP, Patel M, Szarek M, Yusuf S, Eikelboom J, Bonaca MP. Low-dose rivaroxaban and aspirin among patients with peripheral artery disease: a meta-analysis of the COMPASS and VOYAGER trials. Eur J Prev Cardiol. 2022 May 5;29(5):e181-e189.

Kuijpers MJE, Heemskerk JWM, Jurk K. Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation. Int J Mol Sci. 2022 May 23;23(10):5825.

Panova-Noeva M, Falanga A. Editorial: Role of the Platelet Phenomenon in Cardiovascular Diseases and Cancer. Front Cardiovasc Med. 2022 Mar 23;9:859770.

ICM-VTE General Delegates. Recommendations from the ICM-VTE: General. J Bone Joint Surg Am. 2022 Mar 16;104(Suppl 1):4-162.

Pontarollo G, Kiouptsi K, Bayer F, Reinhardt C, 2022. In: Glibetic, M. (Ed.), Comprehensive Gut Microbiota, vol. 2. Elsevier, pp. 319–338.

Spaetgens B, Nagy M, Ten Cate H. Antiplatelet Therapy in Patients With COVID-19-More Is Less? JAMA. 2022 Jan 18;327(3):223-224.

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Originalartikel 2021

Marini F, Ludt A, Linke J, Strauch K. GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. BMC Bioinformatics. 2021 Dec 23;22(1):610.

Hobohm L, Kölmel S, Niemann C, Kümpers P, Krieg VJ, Bochenek ML, Lukasz AH, Reiss Y, Plate KH, Liebetrau C, Wiedenroth CB, Guth S, Münzel T, Hasenfuß G, Wenzel P, Mayer E, Konstantinides SV, Schäfer K, Lankeit M. Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease. Eur Respir J. 2021 Dec 2;58(6):2004196.

Sebastian T, Barco S, Kreuzpointner R, Konstantinides S, Kucher N. Reversal of cardiopulmonary exercise intolerance in patients with post-thrombotic obstruction of the inferior vena cava. Thromb Res. 2021 Dec;208:219-225.

Hess CN, Debus ES, Nehler MR, Anand SS, Patel MR, Szarek M, Capell WH, Hsia J, Beckman JA, Brodmann M, Diaz R, Habertheuer P, Leeper NJ, Powell RJ, Sillesen H, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM, Bonaca MP. Reduction in Acute Limb Ischemia With Rivaroxaban Versus Placebo in Peripheral Artery Disease After Lower Extremity Revascularization: Insights From VOYAGER PAD. Circulation. 2021 Dec 7;144(23):1831-1841.

Iglesias MJ, Kruse LD, Sanchez-Rivera L, Enge L, Dusart P, Hong MG, Uhlén M, Renné T, Schwenk JM, Bergstrom G, Odeberg J, Butler LM. Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors. Arterioscler Thromb Vasc Biol. 2021 Dec;41(12):2990-3004.

Geyer M, Keller K, Tamm AR, Born S, Bachmann K, Ruf TF, Kreidel F, Hahad O, Petrescu A, Schnitzler K, Schmitt VH, da Rocha E Silva JG, Hell MM, Schulz E, Münzel T, von Bardeleben RS. Early symptomatic benefit indicates long-term prognosis after transcatheter mitral valve edge-to-edge repair in functional and degenerative etiology. Int J Cardiol. 2021 Dec 1;344:141-146.

Schnorbus B, Jurk K, Lackner KJ, Welk C, Münzel T, Gori T. Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial. Front Cardiovasc Med. 2021 Dec 13;8:780605.

Pływaczewska M, Jiménez D, Lankeit M, Pruszczyk P, Kostrubiec M. A Comparison of GFR Calculated by Cockcroft-Gault vs. MDRD Formula in the Prognostic Assessment of Patients with Acute Pulmonary Embolism. Dis Markers. 2021 Dec 8;2021:6655958.

Willems LH, Nagy M, Ten Cate H, Spronk HMH, Jacobs LMC, Kranendonk J, van Leeuwen M, Meijer D, Middeldorp S, Groh LA, Warlé MC. ChAdOx1 vaccination, blood coagulation, and inflammation: No effect on coagulation but increased interleukin-6. Res Pract Thromb Haemost. 2021 Dec 7;5(8):e12630.

Kaemmerer AS, Gorenflo M, Huscher D, Pittrow D, Ewert P, Pausch C, Delcroix M, Ghofrani HA, Hoeper MM, Kozlik-Feldmann R, Skride A, Stähler G, Vizza CD, Jureviciene E, Jancauskaite D, Gumbiene L, Ewert R, Dähnert I, Held M, Halank M, Skowasch D, Klose H, Wilkens H, Milger K, Jux C, Koestenberger M, Scelsi L, Brunnemer E, Hofbeck M, Ulrich S, Vonk Noordegraaf A, Lange TJ, Bruch L, Konstantinides S, Claussen M, Löffler-Ragg J, Wirtz H, Apitz C, Neidenbach R, Freilinger S, Nemes A, Opitz C, Grünig E, Rosenkranz S. Medical treatment of pulmonary hypertension in adults with congenital heart disease: updated and extended results from the International COMPERA-CHD Registry. Cardiovasc Diagn Ther. 2021 Dec;11(6):1255-1268.

Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T. Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia. Blood. 2021 Dec 2;138(22):2256-2268.

Fieß A, Urschitz MS, Marx-Groß S, Nagler M, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of Birth Weight with Central and Peripheral Corneal Thickness in Adulthood-Results from the Population-Based German Gutenberg Health Study. Children (Basel). 2021 Nov 4;8(11):1006.

Hess CN, Patel MR, Bauersachs RM, Anand SS, Debus ES, Nehler MR, Fanelli F, Yeh RW, Secemsky EA, Beckman JA, Mauri L, Govsyeyev N, Capell WH, Brackin T, Berkowitz SD, Muehlhofer E, Haskell LP, Hiatt WR, Bonaca MP. Safety and Effectiveness of Paclitaxel Drug-Coated Devices in Peripheral Artery Revascularization: Insights From VOYAGER PAD. J Am Coll Cardiol. 2021 Nov 2;78(18):1768-1778.

Keller K, Hobohm L, Ostad MA, Karbach S, Espinola-Klein C, Münzel T, Gelfand JM, Konstantinides SV, Steinbrink K, Gori T. Psoriasis and its impact on the clinical outcome of patients with pulmonary embolism. Int J Cardiol. 2021 Nov 15;343:114-121.

Fieß A, Wagner FM, Urschitz MS, Nagler M, Stoffelns B, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of Birth Weight With Foveolar Thickness in Adulthood: Results From a Population-Based Study. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):9.

Siemer S, Bauer TA, Scholz P, Breder C, Fenaroli F, Harms G, Dietrich D, Dietrich J, Rosenauer C, Barz M, Becker S, Strieth S, Reinhardt C, Fauth T, Hagemann J, Stauber RH. Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin. ACS Nano. 2021 Nov 5.

Stamm P, Kirmes I, Palmer A, Molitor M, Kvandova M, Kalinovic S, Mihalikova D, Reid G, Wenzel P, Münzel T, Daiber A, Jansen T. Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function. Life Sci. 2021 Nov 1;284:119879.

Keller K, Sinning C, Schulz A, Jünger C, Schmitt VH, Hahad O, Zeller T, Beutel M, Pfeiffer N, Strauch K, Blankenberg S, Lackner KJ, Prochaska JH, Schulz E, Münzel T, Wild PS. Right atrium size in the general population. Sci Rep. 2021 Nov 18;11(1):22523.

Xia N, Hasselwander S, Reifenberg G, Habermeier A, Closs EI, Mimmler M, Jung R, Karbach S, Lagrange J, Wenzel P, Daiber A, Münzel T, Hövelmeyer N, Waisman A, Li H. B Lymphocyte-Deficiency in Mice Causes Vascular Dysfunction by Inducing Neutrophilia. Biomedicines. 2021 Nov 14;9(11):1686.

Keller K, Wöllner J, Schmitt VH, Ostad MA, Sagoschen I, Münzel T, Espinola-Klein C, Hobohm L. Risk Factors for Pulmonary Embolism in Patients with Paralysis and Deep Venous Thrombosis. J Clin Med. 2021 Nov 19;10(22):5412.

D'Alessandro E, Scaf B, van Oerle R, van Nieuwenhoven FA, van Hunnik A, Verheule S, Schotten U, Ten Cate H, Spronk HMH. Thrombin generation by calibrated automated thrombography in goat plasma: Optimization of an assay. Res Pract Thromb Haemost. 2021 Nov 21;5(8):e12620.

Nevo N, Ordonez-Moreno LA, Gur-Cohen S, Avemaria F, Bhattacharya S, Khatib-Massalha E, Bertagna M, Haddad M, Chakrabarti P, Ruf W, Lapidot T, Kollet O. Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation. Leukemia. 2021 Nov;35(11):3334-3338.

Kobayashi S, Koizume S, Takahashi T, Ueno M, Oishi R, Nagashima S, Sano Y, Fukushima T, Tezuka S, Morimoto M, Nakamura S, Narimatsu H, Ruf W, Miyagi Y. Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer. Cancer Sci. 2021 Nov;112(11):4679-4691.

D'Alessandro E, Scaf B, Munts C, van Hunnik A, Trevelyan CJ, Verheule S, Spronk HMH, Turner NA, Ten Cate H, Schotten U, van Nieuwenhoven FA. Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1. Cells. 2021 Oct 30;10(11):2958.

Boon GJAM, Janssen SMJ, Barco S, Bogaard HJ, Ghanima W, Kroft LJM, Meijboom LJ, Ninaber MK, Nossent EJ, Spruit MA, Symersky P, Vliegen HW, Noordegraaf AV, Huisman MV, Siegerink B, Abbink JJ, Klok FA. Efficacy and safety of a 12-week outpatient pulmonary rehabilitation program in Post-PE Syndrome. Thromb Res. 2021 Oct;206:66-75.

Aboyans V, Bauersachs R, Mazzolai L, Brodmann M, Palomares JFR, Debus S, Collet JP, Drexel H, Espinola-Klein C, Lewis BS, Roffi M, Sibbing D, Sillesen H, Stabile E, Schlager O, De Carlo M. Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy. Eur Heart J. 2021 Oct 14;42(39):4013-4024.

Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB. Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J. 2021 Oct 14;42(39):4077-4088.

Zhong X, Wang T, Xie Y, Wang M, Zhang W, Dai L, Lai J, Nie X, He X, Madhusudhan T, Zeng H, Wang H. Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis. Front Cardiovasc Med. 2021 Oct 29;8:758158.

Ebner M, Sentler C, Harjola VP, Bueno H, Lerchbaumer MH, Hasenfuß G, Eckardt KU, Konstantinides SV, Lankeit M. Outcome of patients with different clinical presentations of high-risk pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 Oct 1;10(7):787-796.

Keller K, Schmitt VH, Vosseler M, Brochhausen C, Münzel T, Hobohm L, Espinola-Klein C. Diabetes Mellitus and Its Impact on Patient-Profile and In-Hospital Outcomes in Peripheral Artery Disease. J Clin Med. 2021 Oct 28;10(21):5033.

Fogarty H, Townsend L, Morrin H, Ahmad A, Comerford C, Karampini E, Englert H, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, McGonagle D, Ni Cheallaigh C, Baker RI, Renné T, Ward SE, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Persistent endotheliopathy in the pathogenesis of long COVID syndrome. J Thromb Haemost. 2021 Oct;19(10):2546-2553.

Sebastian T, Barco S, Lichtenberg M, Stahlhoff S, Schlager O, Jalaie H, de Graaf R, Erbel C, Massmann A, Schindewolf M, Kucher N. Twelve-month clinical outcomes of a hybrid oblique self-expanding nitinol stent used for the treatment of post-thrombotic syndrome with common iliac vein compression: The TOPOS study. Vasc Med. 2021 Oct;26(5):569-571.

Haist M, Stege H, Pemler S, Heinz J, Fleischer MI, Graf C, Ruf W, Loquai C, Grabbe S. Anticoagulation with Factor Xa Inhibitors Is Associated with Improved Overall Response and Progression-Free Survival in Patients with Metastatic Malignant Melanoma Receiving Immune Checkpoint Inhibitors-A Retrospective, Real-World Cohort Study. Cancers (Basel). 2021 Oct 12;13(20):5103.

Debus ES, Nehler MR, Govsyeyev N, Bauersachs RM, Anand SS, Patel MR, Fanelli F, Capell WH, Brackin T, Hinterreiter F, Krievins D, Nault P, Piffaretti G, Svetlikov A, Jaeger N, Hess CN, Sillesen HH, Conte M, Mills J, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR, Bonaca MP. Effect of Rivaroxaban and Aspirin in Patients With Peripheral Artery Disease Undergoing Surgical Revascularization: Insights From the VOYAGER PAD Trial. Circulation. 2021 Oct 5;144(14):1104-1116.

Prochaska JH, Arnold N, Falcke A, Kopp S, Schulz A, Buch G, Moll S, Panova-Noeva M, Jünger C, Eggebrecht L, Pfeiffer N, Beutel M, Binder H, Grabbe S, Lackner KJ, Ten Cate-Hoek A, Espinola-Klein C, Münzel T, Wild PS. Chronic venous insufficiency, cardiovascular disease, and mortality: a population study. Eur Heart J. 2021 Oct 21;42(40):4157-4165.

Krantz MJ, Debus SE, Hsia J, Patel MR, Anand SS, Nehler MR, Hess CN, Capell WH, Bracken T, Szarek M, Mátyás L, Krievins DK, Nault P, Stefanov S, Haskell LP, Berkowitz SD, Muehlhofer E, Hiatt WR, Bauersachs RM, Bonaca MP. Low-dose rivaroxaban plus aspirin in older patients with peripheral artery disease undergoing acute limb revascularization: insights from the VOYAGER PAD trial. Eur Heart J. 2021 Oct 14;42(39):4040-4048.

Klok FA, Toenges G, Mavromanoli AC, Barco S, Ageno W, Bouvaist H, Brodmann M, Cuccia C, Couturaud F, Dellas C, Dimopoulos K, Duerschmied D, Empen K, Faggiano P, Ferrari E, Galiè N, Galvani M, Ghuysen A, Giannakoulas G, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Meneveau N, Münzel T, Palazzini M, Petris AO, Piovaccari G, Salvi A, Schellong S, Schmidt KH, Verschuren F, Schmidtmann I, Meyer G, Konstantinides SV; PEITHO-2 investigators. Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial. Lancet Haematol. 2021 Sep;8(9):e627-e636.

Heestermans M, Naudin C, Mailer RK, Konrath S, Klaetschke K, Jämsä A, Frye M, Deppermann C, Pula G, Kuta P, Friese MA, Gelderblom M, Sickmann A, Preston RJS, Nofer JR, Rose-John S, Butler LM, Salomon O, Stavrou EX, Renné T. Identification of the factor XII contact activation site enables sensitive coagulation diagnostics. Nat Commun. 2021 Sep 22;12(1):5596.

Hollerbach A, Müller-Calleja N, Pedrosa D, Canisius A, Sprinzl MF, Falter T, Rossmann H, Bodenstein M, Werner C, Sagoschen I, Münzel T, Schreiner O, Sivanathan V, Reuter M, Niermann J, Galle PR, Teyton L, Ruf W, Lackner KJ. Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19. J Thromb Haemost. 2021 Sep;19(9):2335-2347.

Chu G, Valerio L, van der Wall SJ, Barco S, Konstantinides S, Huisman MV, Klok FA. Tailoring anticoagulant treatment of patients with atrial fibrillation using a novel bleeding risk score. Heart. 2020 Sep 9:heartjnl-2019-316305.

Wasielica-Poslednik J, Hampel U, Ries L, Faysal R, Schulz A, Prochaska JH, Wild PS, Schmidtmann I, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Prevalence of corneal arcus and associated factors in a German population-Results from the Gutenberg Health Study. PLoS One. 2021 Sep 21;16(9):e0255893.

Schmitt VH, Prochaska JH, Föll AS, Schulz A, Keller K, Hahad O, Koeck T, Tröbs SO, Rapp S, Beutel M, Pfeiffer N, Strauch K, Lackner KJ, Münzel T, Wild PS. Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus. Sci Rep. 2021 Sep 24;11(1):19012.

Kangro K, Roose E, Joly BS, Sinkovits G, Falter T, von Auer C, Rossmann H, Reti M, Voorberg J, Prohászka Z, Lämmle B, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura. Blood Adv. 2021 Sep 14;5(17):3427-3435.

Kulka HC, Zeller A, Fornaro J, Wuillemin WA, Konstantinides S, Christ M. Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint. Dtsch Arztebl Int. 2021 Sep 17;118(37):618-628.

Boon GJAM, van den Hout WB, Barco S, Bogaard HJ, Delcroix M, Huisman MV, Konstantinides SV, Meijboom LJ, Nossent EJ, Symersky P, Vonk Noordegraaf A, Klok FA. A model for estimating the health economic impact of earlier diagnosis of chronic thromboembolic pulmonary hypertension. ERJ Open Res. 2021 Sep 6;7(3):00719-2020.

Formes H, Bernardes JP, Mann A, Bayer F, Pontarollo G, Kiouptsi K, Schäfer K, Attig S, Nikolova T, Hofmann TG, Schattenberg JM, Todorov H, Gerber S, Rosenstiel P, Bopp T, Sommer F, Reinhardt C. The gut microbiota instructs the hepatic endothelial cell transcriptome. iScience. 2021 Sep 10;24(10):103092.

Reagh JJ, Zheng H, Stolz U, Parry BA, Chang AM, House SL, Giordano NJ, Cohen J, Singer AJ, Francis S, Prochaska JH, Zeserson E, Wild PS, Limkakeng AT Jr, Walters EL, LoVecchio F, Theodoro D, Hollander JE, Kabrhel C, Fermann GJ. Sex-related differences in D-dimer levels for venous thromboembolism screening. Acad Emerg Med. 2021 Aug;28(8):873-881.

Göbel S, Prochaska JH, Tröbs SO, Panova-Noeva M, Espinola-Klein C, Michal M, Lackner KJ, Gori T, Münzel T, Wild PS. Rationale, design and baseline characteristics of the MyoVasc study: A prospective cohort study investigating development and progression of heart failure. Eur J Prev Cardiol. 2021 Aug 9;28(9):1009-1018.

Dahlen B, Schulz A, Göbel S, Tröbs SO, Schwuchow-Thonke S, Spronk HM, Prochaska JH, Arnold N, Lackner KJ, Gori T, Ten Cate H, Münzel T, Wild PS, Panova-Noeva M. The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study. ESC Heart Fail. 2021 Aug;8(4):2991-3001.

Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM. CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models. J Thromb Haemost. 2021 Aug;19(8):1932-1947.

Milstone LM, Jackson C, Becker RC, Camire R, Knabb R, Mann K, Ruf W, Wexler RR, Wood J. Discussion of talks from the symposium: Factor X: From thrombokinase to oral anti-coagulants and beyond. J Thromb Thrombolysis. 2021 Aug;52(2):408-413.

Keller K, Hobohm L, Schmidtmann I, Münzel T, Baldus S, von Bardeleben RS. Centre procedural volume and adverse in-hospital outcomes in patients undergoing percutaneous transvenous edge-to-edge mitral valve repair using MitraClip® in Germany. Eur J Heart Fail. 2021 Aug;23(8):1380-1389.

Keller K, Hobohm L, Schmidtmann I, Münzel T, Baldus S, von Bardeleben RS. Centre procedural volume and adverse in-hospital outcomes in patients undergoing percutaneous transvenous edge-to-edge mitral valve repair using MitraClip® in Germany. Eur J Heart Fail. 2021 Aug;23(8):1380-1389.

Schmitt VH, Billaudelle AM, Schulz A, Keller K, Hahad O, Tröbs SO, Koeck T, Michal M, Schuster AK, Toenges G, Lackner KJ, Prochaska JH, Münzel T, Wild PS. Disturbed Glucose Metabolism and Left Ventricular Geometry in the General Population. J Clin Med. 2021 Aug 27;10(17):3851.

Arnold N, Deiseroth A, Hahad O, Diestelmeier S, Schulz A, Daubenbüchel A, Gori T, Binder H, Pfeiffer N, Prochaska J, Beutel M, Lackner KJ, Münzel T, Wild PS. Domains of Physical Activity in Relation to Stiffness Index in the General Population. J Am Heart Assoc. 2021 Aug 17;10(16):e020930.

Bauersachs R, Gerlach HE, Heinken A, Hoffmann U, Langer F, Noppeney T, Pittrow D, Klotsche J, Rabe E. Management and Outcomes of Patients with Isolated Superficial Vein Thrombosis under Real Life Conditions (INSIGHTS-SVT). Eur J Vasc Endovasc Surg. 2021 Aug;62(2):241-249.

Beckmann L, Rolling CC, Voigtländer M, Mäder J, Klingler F, Schulenkorf A, Lehr C, Bokemeyer C, Ruf W, Langer F. Bacitracin and Rutin Regulate Tissue Factor Production in Inflammatory Monocytes and Acute Myeloid Leukemia Blasts. Cancers (Basel). 2021 Aug 4;13(16):3941.

More P, Bindila L, Wild P, Andrade-Navarro M, Fontaine JF. LipiDisease: associate lipids to diseases using literature mining. Bioinformatics. 2021 Aug 6;37(21):3981–2.

Keller K, Hobohm L, Ostad MA, Göbel S, Lankeit M, Konstantinides S, Münzel T, Wenzel P. Temporal trends and predictors of inhospital death in patients hospitalised for heart failure in Germany. Eur J Prev Cardiol. 2021 Aug 9;28(9):990-997.

Hobohm L, Sebastian T, Valerio L, Mahmoudpour SH, Vatsakis G, Johner F, Keller K, Münzel T, Kucher N, Konstantinides SV, Barco S. Sterblichkeit der Lungenembolie in der DACH-Region [Trends in mortality related to pulmonary embolism in the DACH countries]. Med Klin Intensivmed Notfmed. 2021 Aug 24. German.

Matli B, Schulz A, Koeck T, Falter T, Lotz J, Rossmann H, Pfeiffer N, Beutel M, Münzel T, Strauch K, Wild PS, Lackner KJ. Distribution of HOMA-IR in a population-based cohort and proposal for reference intervals. Clin Chem Lab Med. 2021 Aug 11;59(11):1844-1851.

Fieß A, Ponto KA, Urschitz MS, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Birthweight and its association with retinal vessel equivalents - Results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2021 Aug;99(5):e773-e774.

Wild J, Distelmeier S, Keil P, Weinmann A, Münzel T, Weinmann-Menke J, Kraus D. Non-bacterial thrombotic endocarditis in a patient with pancreatic carcinoma. Echocardiography. 2021 Aug;38(8):1455-1458.

Mumoli N, Evangelista I, Colombo A, Conte G, Mazzone A, Barco S. Transient perivascular inflammation of the carotid artery (TIPIC) syndrome in a patient with COVID-19.https://pubmed.ncbi.nlm.nih.gov/34000422/ Int J Infect Dis. 2021 Jul;108:126-128.

Wang T, Wu J, Dong W, Wang M, Zhong X, Zhang W, Dai L, Xie Y, Liu Y, He X, Liu W, Madhusudhan T, Zeng H, Wang H. The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation. Int J Biol Sci. 2021 Jul 13;17(12):2984-2999

Schmitt VH, Hobohm L, Münzel T, Wenzel P, Gori T, Keller K. Impact of diabetes mellitus on mortality rates and outcomes in myocardial infarction. Diabetes Metab. 2021 Jul;47(4):101211

Rosner AK, Closs EI, Habermeier A, Gericke A, Binder H, Scharrer I, Pfeiffer N, Ponto KA. Asymmetrisches Dimethylarginin (ADMA) bei retinalen Venenverschlüssen – Ergebnisse aus der Gutenberg-RVO-Studie [Asymmetric dimethylarginine (ADMA) in retinal vein occlusion-Results from the Gutenberg RVO study]. Ophthalmologe. 2021 Jul;118(7):684-69

Schwaegermann MK, Hobohm L, Rausch J, Reuter M, Griemert TF, Sivanathan V, Falter T, Sprinzl MF, Lackner KJ, Galle PR, Konstantinides S, Theobald M, von Auer C. COVID-19 as a Potential Trigger for Immune Thrombotic Thrombocytopenic Purpura and Reason for an Unusual Treatment: A Case Report. Hamostaseologie. 2021 Jul 29.

Mumoli N, Conte G, Cei M, Vitale J, Capra R, Rotiroti G, Porta C, Monolo D, Colombo A, Mazzone A, Kucher N, Konstantinides SV, Dentali F, Barco S. In-hospital fatality and venous thromboembolism during the first and second COVID-19 waves at a center opting for standard-dose thromboprophylaxis. Thromb Res. 2021 Jul;203:82-84.

Michal M, Eggebrecht L, Göbel S, Panova-Noeva M, Nagler M, Arnold N, Lauterbach M, Bickel C, Wiltink J, Beutel ME, Münzel T, Wild PS, Prochaska JH. The relevance of depressive symptoms for the outcome of patients receiving vitamin K antagonists: results from the thrombEVAL cohort study. Eur Heart J Cardiovasc Pharmacother. 2021 Jul 23;7(4):271-279.

Roncon L, Zuin M, Barco S, Zuliani G, Konstantinides SV. Increased interest in acute pulmonary embolism in Italy during the COVID-19 pandemic: a google trends-based analysis. J Thromb Thrombolysis. 2021 Jul;52(1):92-94.

Helmstädter J, Keppeler K, Aust F, Küster L, Frenis K, Filippou K, Vujacic-Mirski K, Tsohataridis S, Kalinovic S, Kröller-Schön S, Oelze M, Bosmann M, Münzel T, Daiber A, Steven S. GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation. Antioxidants (Basel). 2021 Jul 23;10(8):1175.

Bayer F, Ascher S, Kiouptsi K, Kittner JM, Stauber RH, Reinhardt C. Colonization with Altered Schaedler Flora Impacts Leukocyte Adhesion in Mesenteric Ischemia-Reperfusion Injury. Microorganisms. 2021 Jul 27;9(8):1601.

Ten Cate V, Koeck T, Prochaska J, Schulz A, Panova-Noeva M, Rapp S, Eggebrecht L, Lenz M, Glunz J, Sauer M, Ewert R, Halank M, Münzel T, Heitmeier S, Andrade-Navarro MA, Lackner KJ, Konstantinides SV, Leineweber K, Wild PS. A targeted proteomics investigation of the obesity paradox in venous thromboembolism. Blood Adv. 2021 Jul 27;5(14):2909-2918.

Bauersachs RM, Szarek M, Brodmann M, Gudz I, Debus ES, Nehler MR, Anand SS, Patel MR, Hess CN, Capell WH, Rogers K, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR, Bonaca MP; VOYAGER PAD Committees and Investigators. Total Ischemic Event Reduction With Rivaroxaban After Peripheral Arterial Revascularization in the VOYAGER PAD Trial. J Am Coll Cardiol. 2021 Jul 27;78(4):317-326.

Valerio L, Barco S, Jankowski M, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Hoeper MM, Klok FA, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C, Schmidt KH, Seyfarth HJ, Trudzinski F, Wachter R, Wilkens H, Wild PS, Konstantinides SV. Quality of Life 3 and 12 Months Following Acute Pulmonary Embolism: Analysis From a Prospective Multicenter Cohort Study. Chest. 2021 Jun;159(6):2428-2438.

Valerio L, Turatti G, Klok FA, Konstantinides SV, Kucher N, Roncon L, Zuin M, Barco S. Prevalence of pulmonary embolism in 127 945 autopsies performed in cancer patients in the United States between 2003 and 2019. J Thromb Haemost. 2021 Jun;19(6):1591-1593.

Keller K, Hobohm L, Schmitt VH, Engelhardt M, Wenzel P, Post F, Münzel T, Gori T, Friedmann-Bette B. Total numbers and in-hospital mortality of patients with myocardial infarction in Germany during the FIFA soccer world cup 2014. Sci Rep. 2021 Jun 17;11(1):11330.

Lanza E, Mancuso ME, Messana G, Ferrazzi P, Lisi C, Di Micco P, Barco S, Balzarini L, Lodigiani C. Compromised Lung Volume and Hemostatic Abnormalities in COVID-19 Pneumonia: Results from an Observational Study on 510 Consecutive Patients. J Clin Med. 2021 Jun 29;10(13):2894.

Dahlen B, Müller F, Tröbs SO, Heidorn MW, Schulz A, Arnold N, Hermanns MI, Schwuchow-Thonke S, Prochaska JH, Gori T, Ten Cate H, Lackner KJ, Münzel T, Wild PS, Panova-Noeva M. Sex-Specific Relationship Between Parathyroid Hormone and Platelet Indices in Phenotypes of Heart Failure-Results From the MyoVasc Study. Front Cardiovasc Med. 2021 Jun 16;8:682521.

Valerio L, Corsi G, Granziera S, Holm K, Hotz MA, Jankowski M, Konstantinides SV, Kucher N, Nicoletti T, Reinhardt C, Righini C, Sacco C, Trinchero A, Zane F, Pecci A, Barco S. Sex differences in Lemierre syndrome: Individual patient-level analysis. Thromb Res. 2021 Jun;202:36-39.

Barco S, Valerio L, Gallo A, Turatti G, Mahmoudpour SH, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Goldhaber SZ, Guillermo Esposito MC, Klok FA, Kucher N, McLintock C, Ní Áinle F, Simioni P, Spirk D, Spyropoulos AC, Urano T, Zhai ZG, Hunt BJ, Konstantinides SV. Global reporting of pulmonary embolism-related deaths in the World Health Organization mortality database: Vital registration data from 123 countries. Res Pract Thromb Haemost. 2021 Jun 15;5(5):e12520.

Tarasco E, Bütikofer L, Friedman KD, George JN, Hrachovinova I, Knöbl PN, Matsumoto M, von Krogh AS, Aebi-Huber I, Cermakova Z, Górska-Kosicka M, Jalowiec KA, Largiadèr CR, Prohászka Z, Sinkovits G, Windyga J, Lämmle B, Kremer Hovinga JA. Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura. Blood. 2021 Jun 24;137(25):3563-3575.

Leister H, Luu M, Staudenraus D, Lopez Krol A, Mollenkopf HJ, Sharma A, Schmerer N, Schulte LN, Bertrams W, Schmeck B, Bosmann M, Steinhoff U, Visekruna A. Pro- and Antitumorigenic Capacity of Immunoproteasomes in Shaping the Tumor Microenvironment. Cancer Immunol Res. 2021 Jun;9(6):682-692.

Giustozzi M, Valerio L, Agnelli G, Becattini C, Fronk EM, Klok FA, Konstantinides SV, Vedovati MC, Cohen AT, Barco S. Sex-specific differences in the presentation, clinical course, and quality of life of patients with acute venous thromboembolism according to baseline risk factors. Insights from the PREFER in VTE. Eur J Intern Med. 2021 Jun;88:43-51.

Neulen A, Molitor M, Kosterhon M, Pantel T, Karbach SH, Wenzel P, Gaul T, Ringel F, Thal SC. Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound. https://pubmed.ncbi.nlm.nih.gov/34152320/J Vis Exp. 2021 Jun 3;(172).

Geiß C, Witzler C, Poschet G, Ruf W, Régnier-Vigouroux A. Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells. Eur J Immunol. 2021 May;51(5):1246-1261.

Gerstenberger E, Stoffelns B, Nickels S, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Incidence of Retinal Detachment in Germany: Results from the Gutenberg Health Study. Ophthalmologica. 2021;244(2):133-140.

Bogucka K, Marini F, Rosigkeit S, Schloeder J, Jonuleit H, David K, Schlackow M, Rajalingam K. ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis. Cancer Gene Ther. 2021 May;28(5):359-374.

Rukoyatkina N, Shpakova V, Sudnitsyna J, Panteleev M, Makhoul S, Gambaryan S, Jurk K. https://pubmed.ncbi.nlm.nih.gov/34065600/Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis. Int J Mol Sci. 2021 May 20;22(10):5405.

Tibubos AN, Otten D, Zöller D, Binder H, Wild PS, Fleischer T, Johar H, Atasoy S, Schulze L, Ladwig KH, Schomerus G, Linkohr B, Grabe HJ, Kruse J, Schmidt CO, Münzel T, König J, Brähler E, Beutel ME. Bidimensional structure and measurement equivalence of the Patient Health Questionnaire-9: sex-sensitive assessment of depressive symptoms in three representative German cohort studies. BMC Psychiatry. 2021 May 5;21(1):238.

Mirshahi A, Schneider A, Latz C, Ponto KA. Perioperative pupil size in low-energy femtosecond laser-assisted cataract surgery. PLoS One. 2021 May 17;16(5):e0251549.

Knopp T, Bieler T, Jung R, Ringen J, Molitor M, Jurda A, Münzel T, Waisman A, Wenzel P, Karbach SH, Wild J. Effects of Dietary Protein Intake on Cutaneous and Systemic Inflammation in Mice with Acute Experimental Psoriasis. https://pubmed.ncbi.nlm.nih.gov/34072973/Nutrients. 2021 May 31;13(6):1897.

Mavromanoli AC, Barco S, Konstantinides SV. Antithrombotics and new interventions for venous thromboembolism: Exploring possibilities beyond factor IIa and factor Xa inhibition. Res Pract Thromb Haemost. 2021 May 18;5(4):10.1002/rth2.12509

Spirk D, Sebastian T, Barco S, Banyai M, Beer JH, Mazzolai L, Baldi T, Aujesky D, Hayoz D, Engelberger RP, Kaeslin T, Korte W, Escher R, Husmann M, Blondon M, Kucher N. Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thromb Haemost. 2021 May;121(5):641-649

Wild J, Jung R, Knopp T, Efentakis P, Benaki D, Grill A, Wegner J, Molitor M, Garlapati V, Rakova N, Markó L, Marton A, Mikros E, Münzel T, Kossmann S, Rauh M, Nakano D, Kitada K, Luft F, Waisman A, Wenzel P, Titze J, Karbach S. Aestivation motifs explain hypertension and muscle mass loss in mice with psoriatic skin barrier defect. Acta Physiol (Oxf). 2021 May;232(1):e13628.

Herken K, Glauner M, Robert SC, Maas M, Zippel S, Nowak-Göttl U, Zieger B, Lahav J, Fender AC, Jurk K, Kehrel BE. Age-Dependent Control of Collagen-Dependent Platelet Responses by Thrombospondin-1-Comparative Analysis of Platelets from Neonates, Children, Adolescents, and Adults. Int J Mol Sci. 2021 May 5;22(9):4883.

Hegewald J, Romero Starke K, Garthus-Niegel S, Schulz A, Nübling M, Latza U, Jankowiak S, Liebers F, Rossnagel K, Riechmann-Wolf M, Letzel S, Arnold N, Beutel M, Gianicolo E, Pfeiffer N, Lackner K, Münzel T, Wild P, Seidler A. Work-life conflict and cardiovascular health: 5-year follow-up of the Gutenberg Health Study. PLoS One. 2021 May 7;16(5):e0251260.

Lerchbaumer MH, Ebner M, Ritter CO, Steimke L, Rogge NIJ, Sentler C, Thielmann A, Hobohm L, Keller K, Lotz J, Hasenfuß G, Wachter R, Hamm B, Konstantinides SV, Aviram G, Lankeit M. Prognostic value of right atrial dilation in patients with pulmonary embolism. ERJ Open Res. 2021 May 24;7(2):00414-2020.

Waas T, Schulz A, Lotz J, Rossmann H, Pfeiffer N, Beutel ME, Schmidtmann I, Münzel T, Wild PS, Lackner KJ. Distribution of estimated glomerular filtration rate and determinants of its age dependent loss in a German population-based study. Sci Rep. 2021 May 13;11(1):10165.

Rodionov RN, Beyer-Westendorf J, Bode-Böger SM, Eggebrecht L, Konstantinides S, Martens-Lobenhoffer J, Nagler M, Prochaska J, Wild P. Homoarginine and methylarginines independently predict long-term outcome in patients presenting with suspicion of venous thromboembolism. Sci Rep. 2021 May 5;11(1):9569.

Hahad O, Arnold N, Prochaska JH, Panova-Noeva M, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Beutel M, Wild PS, Keaney JF Jr, Daiber A, Münzel T. Cigarette Smoking Is Related to Endothelial Dysfunction of Resistance, but Not Conduit Arteries in the General Population-Results From the Gutenberg Health Study. Front Cardiovasc Med. 2021 May 19;8:674622.

Gresele P, Falcinelli E, Bury L, Pecci A, Alessi MC, Borhany M, Heller PG, Santoro C, Cid AR, Orsini S, Fontana P, De Candia E, Podda G, Kannan M, Jurk K, Castaman G, Falaise C, Guglielmini G, Noris P; BAT-VAL Study Investigators. The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology. J Thromb Haemost. 2021 May;19(5):1364-1371.

Ten Cate V, Prochaska JH, Schulz A, Koeck T, Pallares Robles A, Lenz M, Eggebrecht L, Rapp S, Panova-Noeva M, Ghofrani HA, Meyer FJ, Espinola-Klein C, Lackner KJ, Michal M, Schuster AK, Strauch K, Zink AM, Laux V, Heitmeier S, Konstantinides SV, Münzel T, Andrade-Navarro MA, Leineweber K, Wild PS. Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism. Blood. 2021 May 13;137(19):2681-2693.

Hobohm L, Schmidt FP, Gori T, Schmidtmann I, Barco S, Münzel T, Lankeit M, Konstantinides SV, Keller K. In-hospital outcomes of catheter-directed thrombolysis in patients with pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 May 11;10(3):258-264.

Hobohm L, Schmidt FP, Gori T, Schmidtmann I, Barco S, Münzel T, Lankeit M, Konstantinides SV, Keller K. In-hospital outcomes of catheter-directed thrombolysis in patients with pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 May 11;10(3):258-264.

Geyer M, Keller K, Bachmann K, Born S, Tamm AR, Ruf TF, Kreidel F, Hahad O, Petrescu A, Hell M, Beiras-Fernandez A, Kornberger A, Schulz E, Münzel T, von Bardeleben RS. Concomitant tricuspid regurgitation severity and its secondary reduction determine long-term prognosis after transcatheter mitral valve edge-to-edge repair. Clin Res Cardiol. 2021 May;110(5):676-688.

Ogorodnikov A, Danckwardt S. TRENDseq-A highly multiplexed high throughput RNA 3' end sequencing for mapping alternative polyadenylation. Methods Enzymol. 2021;655:37-72.

Tröbs SO, Prochaska JH, Schwuchow-Thonke S, Schulz A, Müller F, Heidorn MW, Göbel S, Diestelmeier S, Lerma Monteverde J, Lackner KJ, Gori T, Münzel T, Wild PS. Association of Global Longitudinal Strain With Clinical Status and Mortality in Patients With Chronic Heart Failure. JAMA Cardiol. 2021 Apr 1;6(4):448-456.

Ebner M, Pagel CF, Sentler C, Harjola VP, Bueno H, Lerchbaumer MH, Stangl K, Pieske B, Hasenfuß G, Konstantinides SV, Lankeit M. Venous lactate improves the prediction of in-hospital adverse outcomes in normotensive pulmonary embolism. Eur J Intern Med. 2021 Apr;86:25-31

Morla S, Deguchi H, Fernández JA, Ruf W, Brekken RA, Griffin JH. Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids. Blood. 2021 Apr 1;137(13):1839-1842

Guilherme MDS, Nguyen VTT, Reinhardt C, Endres K. Impact of Gut Microbiome Manipulation in 5xFAD Mice on Alzheimer's Disease-Like Pathology. Microorganisms. 2021 Apr 13;9(4):815.

Cuker A, Cataland SR, Coppo P, de la Rubia J, Friedman KD, George JN, Knoebl PN, Kremer Hovinga JA, Lämmle B, Matsumoto M, Pavenski K, Peyvandi F, Sakai K, Sarode R, Thomas MR, Tomiyama Y, Veyradier A, Westwood JP, Scully M. Redefining outcomes in immune TTP: an international working group consensus report. Blood. 2021 Apr 8;137(14):1855-1861.

Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller-Schön S, Bayo Jimenez MT, Hahad O, Oelze M, Jiang S, Wenzel P, Sommer CJ, Frauenknecht KBM, Waisman A, Gericke A, Daiber A, Münzel T, Steven S. Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Basic Res Cardiol. 2021 Apr 30;116(1):31

Neubauer K, Jurk K, Petermann V, Kumm E, Zieger B. Impaired Platelet Function in Sept8-Deficient Mice In Vitro. Thromb Haemost. 2021 Apr;121(4):484-494

Keller K, Münzel T, Hobohm L, Ostad MA. Predictive value of the Kuijer score for bleeding and other adverse in-hospital events in patients with venous thromboembolism. Int J Cardiol. 2021 Apr 15;329:179-184.

Fieß A, Lamparter J, Raum P, Peto T, Ponto KA, Nickels S, Münzel T, Wild PS, Beutel ME, Urschitz MS, Lackner KJ, Pfeiffer N, Schuster AK. Birth Weight and Diabetic Retinopathy: Results From the Population-Based Gutenberg Health Study (GHS). Ophthalmic Epidemiol. 2021 Apr;28(2):122-130.

Müller-Calleja N, Hollerbach A, Royce J, Ritter S, Pedrosa D, Madhusudhan T, Teifel S, Meineck M, Häuser F, Canisius A, Nguyen TS, Braun J, Bruns K, Etzold A, Zechner U, Strand S, Radsak M, Strand D, Gu JM, Weinmann-Menke J, Esmon CT, Teyton L, Lackner KJ, Ruf W. Lipid presentation by the protein C receptor links coagulation with autoimmunity. Science. 2021 Mar 12;371(6534):eabc0956.

Triantafyllias K, Cavagna L, Klonowski A, Drott U, Fiehn C, Wendel S, Bergner R, de Blasi M, Voll RE, Baulmann J, Konstantinides S, Galle PR, Schwarting A. Possible misclassification of cardiovascular risk by SCORE in antisynthetase syndrome: results of the pilot multicenter study RI.CAR.D.A. Rheumatology (Oxford). 2021 Mar 2;60(3):1300-1312.

Valerio L, Zane F, Sacco C, Granziera S, Nicoletti T, Russo M, Corsi G, Holm K, Hotz MA, Righini C, Karkos PD, Mahmoudpour SH, Kucher N, Verhamme P, Di Nisio M, Centor RM, Konstantinides SV, Pecci A, Barco S. Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases. J Intern Med. 2021 Mar;289(3):325-339.

Wejbera M, Wölfling K, Dreier M, Michal M, Brähler E, Wiltink J, Schulz A, Wild PS, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. Risk factors, physical and mental health burden of male and female pathological gamblers in the German general population aged 40-80. BMC Psychiatry. 2021 Mar 4;21(1):123.

Rudi WS, Molitor M, Garlapati V, Finger S, Wild J, Münzel T, Karbach SH, Wenzel P. https://pubmed.ncbi.nlm.nih.gov/33807982/ACE Inhibition Modulates Myeloid Hematopoiesis after Acute Myocardial Infarction and Reduces Cardiac and Vascular Inflammation in Ischemic Heart Failure. Antioxidants (Basel). 2021 Mar 5;10(3):396.

Zierold S, Buschmann K, Gachkar S, Bochenek ML, Velmeden D, Hobohm L, Vahl CF, Schäfer K. Brain-Derived Neurotrophic Factor Expression and Signaling in Different Perivascular Adipose Tissue Depots of Patients With Coronary Artery Disease. J Am Heart Assoc. 2021 Mar 16;10(6):e018322.

Shahneh F, Grill A, Klein M, Frauhammer F, Bopp T, Schäfer K, Raker VK, Becker C. Specialized regulatory T cells control venous blood clot resolution through SPARC. Blood. 2021 Mar 18;137(11):1517-1526.

Settelmeier S, Hochadel M, Giannitsis E, Konstantinides S, Voigtländer T, Schmitt C, Haude M, Kerber S, Mudra H, Gonska BD, Senges J, Breuckmann F, Münzel T. Management of Pulmonary Embolism: Results from the German Chest Pain Unit Registry. Cardiology. 2021;146(3):304-310.

Regen T, Isaac S, Amorim A, Núñez NG, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. IL-17 controls central nervous system autoimmunity through the intestinal microbiome. Sci Immunol. 2021 Feb 5;6(56):eaaz6563.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Hackeng TM, Ten Cate H, Wild PS, Spronk HMH. Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample. Thromb Haemost. 2021 Feb;121(2):174-181.

Falter T, Rossmann H, Menge P, Goetje J, Groenwoldt S, Weinmann A, Sivanathan V, Schulz A, Lemmermann NAW, Danckwardt S, Lackner KJ, Galle PR, Scharrer I, Lämmle B, Sprinzl MF. No Evidence for Classic Thrombotic Microangiopathy in COVID-19. J Clin Med. 2021 Feb 9;10(4):671.

Arnold N, Merzenich H, Wingerter A, Schulz A, Schneider A, Prochaska JH, Göbel S, Neu MA, Henninger N, Panova-Noeva M, Eckerle S, Spix C, Schmidtmann I, Lackner KJ, Beutel ME, Pfeiffer N, Münzel T, Faber J, Wild PS. Promotion of Arterial Stiffness by Childhood Cancer and Its Characteristics in Adult Long-Term Survivors. J Am Heart Assoc. 2021 Feb;10(5):e015609

Velásquez Pereira LC, Roose E, Graça NAG, Sinkovits G, Kangro K, Joly BS, Tellier E, Kaplanski G, Falter T, Von Auer C, Rossmann H, Feys HB, Reti M, Prohászka Z, Lämmle B, Voorberg J, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura. J Thromb Haemost. 2021 Feb;19(2):478-488

Rashidi F, Barco S, Kamangar F, Heresi GA, Emadi A, Kaymaz C, Jansa P, Reis A, Rashidi A, Taghizadieh A, Rezaeifar P, Moghimi M, Ghodrati S, Mozafari A, Foumani AA, Tahamtan O, Rafiee E, Abbaspour Z, Khodadadi K, Alamdari G, Boodaghi Y, Rezaei M, Muhammadi MJ, Abbasi M, Movaseghi F, Koohi A, Shakourzad L, Ebrahimi F, Radvar S, Amoozadeh M, Fereidooni F, Naseari H, Movalled K, Ghorbani O, Ansarin K. Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: Prospective results from a multi-center study. Thromb Res. 2021 Feb;198:135-138

Hampel U, Wasielica-Poslednik J, Ries L, Faysal R, Schulz A, Nickels S, Wild PS, Schmidtmann I, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Prevalence of pterygium and identification of associated factors in a German population - results from the Gutenberg Health Study. Acta Ophthalmol. 2021 Feb;99(1):e130-e131.

Di Pilla M, Barco S, Sacco C, Barosi G, Lodigiani C. Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis - case report and systematic review of dabigatran use. Vasa. 2021 Feb;50(2):151-156

Barco S, Schmidtmann I, Ageno W, Anušić T, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jiménez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Lankeit M, Manolis A, Meyer A, Münzel T, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Valerio L, Westerweel PE, Wild PS, Konstantinides SV; HoT-PE Investigators; HoT-PE Trial Investigators are:. Survival and quality of life after early discharge in low-risk pulmonary embolism. Eur Respir J. 2021 Feb 4;57(2):2002368

Neulen A, Molitor M, Kosterhon M, Pantel T, Holzbach E, Rudi WS, Karbach SH, Wenzel P, Ringel F, Thal SC. Correlation of cardiac function and cerebral perfusion in a murine model of subarachnoid hemorrhage. Sci Rep. 2021 Feb 8;11(1):3317.

Alwan F, Vendramin C, Budde U, Liesner R, Taylor A, Thomas M, Lämmle B, Scully M. Assessing thrombogenesis and treatment response in congenital thrombotic thrombocytopenic purpura. EJHaem. 2021 Feb 28;2(2):188-195.

Wendt R, Kalbitz S, Otto F, Falter T, Beige J, Rossmann H, Lämmle B. Diagnosis of Hereditary TTP Caused by Homozygosity for a Rare Complex ADAMTS13 Allele After Salmonella Infection in a 43-Year-Old Asylum Seeker. Front Med (Lausanne). 2021 Feb 26;8:639441.

Schwuchow-Thonke S, Göbel S, Emrich T, Schmitt VH, Fueting F, Klank C, Escher F, Schultheiss HP, Münzel T, Keller K, Wenzel P. Increased C reactive protein, cardiac troponin I and GLS are associated with myocardial inflammation in patients with non-ischemic heart failure. Sci Rep. 2021 Feb 4;11(1):3008.

Machado FVC, Meys R, Delbressine JM, Vaes AW, Goërtz YMJ, van Herck M, Houben-Wilke S, Boon GJAM, Barco S, Burtin C, van 't Hul A, Posthuma R, Franssen FME, Spies Y, Vijlbrief H, Pitta F, Rezek SA, Janssen DJA, Siegerink B, Klok FA, Spruit MA. Construct validity of the Post-COVID-19 Functional Status Scale in adult subjects with COVID-19. Health Qual Life Outcomes. 2021 Feb 3;19(1):40.

Otten D, Tibubos AN, Schomerus G, Brähler E, Binder H, Kruse J, Ladwig KH, Wild PS, Grabe HJ, Beutel ME. Similarities and Differences of Mental Health in Women and Men: A Systematic Review of Findings in Three Large German Cohorts. Front Public Health. 2021 Feb 5;9:553071.

Marini F, Scherzinger D, Danckwardt S. TREND-DB-a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation. Nucleic Acids Res. 2021 Jan 8;49(D1):D243-D253.

Falter T, Böschen S, Schepers M, Beutel M, Lackner K, Scharrer I, Lämmle B. Influence of Personality, Resilience and Life Conditions on Depression and Anxiety in 104 Patients Having Survived Acute Autoimmune Thrombotic Thrombocytopenic Purpura. J Clin Med. 2021 Jan 19;10(2):365.

Molitor M, Rudi WS, Garlapati V, Finger S, Schüler R, Kossmann S, Lagrange J, Nguyen TS, Wild J, Knopp T, Karbach SH, Knorr M, Ruf W, Münzel T, Wenzel P. Nox2+ myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1. Cardiovasc Res. 2021 Jan 1;117(1):162-177.

Eggebrecht L, Ludolph P, Göbel S, Panova-Noeva M, Arnold N, Nagler M, Bickel C, Lauterbach M, Hardt R, Cate HT, Lackner KJ, Espinola-Klein C, Münzel T, Prochaska JH, Wild PS. Cost saving analysis of specialized, eHealth-based management of patients receiving oral anticoagulation therapy: Results from the thrombEVAL study. Sci Rep. 2021 Jan 28;11(1):2577.

Mehling R, Schwenck J, Lemberg C, Trautwein C, Zizmare L, Kramer D, Müller A, Fehrenbacher B, Gonzalez-Menendez I, Quintanilla-Martinez L, Schröder K, Brandes RP, Schaller M, Ruf W, Eichner M, Ghoreschi K, Röcken M, Pichler BJ, Kneilling M. Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions. Theranostics. 2021 Jan 1;11(2):470-490.

Hahad O, Wild PS, Prochaska JH, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Beutel M, Daiber A, Münzel T. Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality? Clin Res Cardiol. 2021 Jan;110(1):29-39.

Ernst M, Brähler E, Otten D, Werner AM, Tibubos AN, Reiner I, Wicke F, Wiltink J, Michal M, Nagler M, Münzel T, Wild PS, König J, Pfeiffer N, Borta A, Lackner KJ, Beutel ME. Inflammation predicts new onset of depression in men, but not in women within a prospective, representative community cohort. Sci Rep. 2021 Jan 26;11(1):2271.

Ernst M, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. Loneliness predicts suicidal ideation and anxiety symptoms in long-term childhood cancer survivors. Int J Clin Health Psychol. 2021 Jan-Apr;21(1):100201.

Fieß A, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Urschitz MS, Lackner KJ, Pfeiffer N, Schuster AK. The relationship of ocular geometry with refractive error in normal and low birth weight adults. J Optom. 2021 Jan-Mar;14(1):50-57.

Adenaeuer A, Ezigbo ED, Fawzy Nazir H, Barco S, Trinchero A, Laubert-Reh D, Strauch K, Wild PS, Lackner KJ, Lämmle B, Rossmann H. c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans. J Thromb Haemost. 2021 Jan;19(1):147-152.

Valerio L, Ferrazzi P, Sacco C, Ruf W, Kucher N, Konstantinides SV, Barco S, Lodigiani C; Humanitas COVID-19 Task Force. Course of D-Dimer and C-Reactive Protein Levels in Survivors and Nonsurvivors with COVID-19 Pneumonia: A Retrospective Analysis of 577 Patients. Thromb Haemost. 2021 Jan;121(1):98-101.

Lommatzsch M, Rabe KF, Taube C, Joest M, Kreuter M, Wirtz H, Blum TG, Kolditz M, Geerdes-Fenge H, Otto-Knapp R, Häcker B, Schaberg T, Ringshausen FC, Vogelmeier CF, Reinmuth N, Reck M, Gottlieb J, Konstantinides S, Meyer FJ, Worth H, Windisch W, Welte T, Bauer T. Risikoabschätzung bei Patienten mit chronischen Atemwegs- und Lungenerkrankungen im Rahmen der SARS-CoV-2-Pandemie [Risk Assessment for Patients with Chronic Respiratory and Pulmonary Conditions in the Context of the SARS-CoV-2 Pandemic - Statement of the German Respiratory Society (DGP) with the Support of the German Association of Respiratory Physicians (BdP)]. Pneumologie. 2021 Jan;75(1):19-30.

Barco S, Valerio L, Ageno W, Cohen AT, Goldhaber SZ, Hunt BJ, Iorio A, Jimenez D, Klok FA, Kucher N, Mahmoudpour SH, Middeldorp S, Münzel T, Tagalakis V, Wendelboe AM, Konstantinides SV. Age-sex specific pulmonary embolism-related mortality in the USA and Canada, 2000-18: an analysis of the WHO Mortality Database and of the CDC Multiple Cause of Death database. Lancet Respir Med. 2021 Jan;9(1):33-42.

Reviews 2021

Valerio L, Pleming W, Pecci A, Barco S. Management of Lemierre Syndrome. Minerva Med. 2021 Dec;112(6):726-739.

Sharma A, Kontodimas K, Bosmann M. The MAVS Immune Recognition Pathway in Viral Infection and Sepsis. Antioxid Redox Signal. 2021 Dec;35(16):1376-1392.

Pruszczyk P, Skowrońska M, Ciurzyński M, Kurnicka K, Lankeit M, Konstantinides S. Assessment of pulmonary embolism severity and the risk of early death. Pol Arch Intern Med. 2021 Dec 22;131(12):16134.

Hobohm L, Lankeit M. Lungenembolie [Pulmonary Embolism]. Pneumologie. 2021 Oct;75(10):800-818

Jonas RA, Rokohl AC, Kakkassery V, Ponto KA, Lohneis P, Heindl LM. Diagnostik von benignen und malignen Tumoren der Orbita [Diagnostics of benign and malignant tumors of the orbit]. Ophthalmologe. 2021 Oct;118(10):987-994.

Ponto KA, Brockmann MA, Koutsimpelas D, Heider J, Ringel FA, Heindl LM, Kakassery V. Exzisionale Chirurgie orbitaler Tumoren [Excisional surgery of orbital tumors]. Ophthalmologe. 2021 Oct;118(10):995-1003.

Ponto KA, Heindl LM, Kakkassery V. SOP Versorgung von orbitalen Tumoren [SOP best care of orbital tumors]. Ophthalmologe. 2021 Oct;118(10):1012.

Jurk K. Thrombozytopenie [Thrombocytopenia]. MMW Fortschr Med. 2021 Oct;163(17):60-62.

Huang J, Zhang P, Solari FA, Sickmann A, Garcia A, Jurk K, Heemskerk JWM. Molecular Proteomics and Signalling of Human Platelets in Health and Disease. Int J Mol Sci. 2021 Sep 13;22(18):9860.

Kulka HC, Zeller A, Fornaro J, Wuillemin WA, Konstantinides S, Christ M. Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint. Dtsch Arztebl Int. 2021 Sep 17;118(37):618-628.

Ruf W. Roles of factor Xa beyond coagulation. J Thromb Thrombolysis. 2021 Aug;52(2):391-396. doi: 10.1007/s11239-021-02458-8.

Rivera-Lebron B, Bauersachs R. Direct oral anticoagulants for the treatment of pulmonary embolism in patients with renal impairment. Thromb Res. 2021 Aug;204:101-107.

Zifkos K, Dubois C, Schäfer K. Extracellular Vesicles and Thrombosis: Update on the Clinical and Experimental Evidence. Int J Mol Sci. 2021 Aug 27;22(17):9317.

Herster F, Karbach S, Chatterjee M, Weber ANR. Platelets: Underestimated Regulators of Autoinflammation in Psoriasis. J Invest Dermatol. 2021 Jun;141(6):1395-1403.

Shiravand Y, Walter U, Jurk K. Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases-Just the Beginning. Hamostaseologie. 2021 Jun;41(3):206-216.

Baidildinova G, Nagy M, Jurk K, Wild PS, Ten Cate H, van der Meijden PEJ. Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease. Front Cardiovasc Med. 2021 Jun 21;8:684920.

Bayer F, Dremova O, Khuu MP, Mammadova K, Pontarollo G, Kiouptsi K, Soshnikova N, May-Simera HL, Endres K, Reinhardt C. The Interplay between Nutrition, Innate Immunity, and the Commensal Microbiota in Adaptive Intestinal Morphogenesis. Nutrients. 2021 Jun 26;13(7):2198.

Lagrange J, Lacolley P, Wahl D, Peyrin-Biroulet L, Regnault V. Shedding Light on Hemostasis in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2021 Jun;19(6):1088-1097.e6.

Sharma A, Kontodimas K, Bosmann M. Nanomedicine: A Diagnostic and Therapeutic Approach to COVID-19. Front Med (Lausanne). 2021 Jun 4;8:648005.

Ozsu S, Gunay E, Konstantinides SV. A review of venous thromboembolism in COVID-19: A clinical perspective. Clin Respir J. 2021 May;15(5):506-512.

Talasaz AH, Sadeghipour P, Kakavand H, Aghakouchakzadeh M, Kordzadeh-Kermani E, Van Tassell BW, Gheymati A, Ariannejad H, Hosseini SH, Jamalkhani S, Sholzberg M, Monreal M, Jimenez D, Piazza G, Parikh SA, Kirtane AJ, Eikelboom JW, Connors JM, Hunt BJ, Konstantinides SV, Cushman M, Weitz JI, Stone GW, Krumholz HM, Lip GYH, Goldhaber SZ, Bikdeli B. Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Apr 20;77(15):1903-1921.

Weissler EH, Aboyans V, Bauersachs R, Brodmann M, Nikol S, Debus S, Patel MR, Jones WS. The Role for Combined Antithrombotic Therapy With Platelet and Coagulation Inhibition After Lower Extremity Revascularization. JACC Cardiovasc Interv. 2021 Apr 12;14(7):796-802

Karnati S, Seimetz M, Kleefeldt F, Sonawane A, Madhusudhan T, Bachhuka A, Kosanovic D, Weissmann N, Krüger K, Ergün S. Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target. Front Cardiovasc Med. 2021 Apr 12;8:649512

Diana T, Ponto KA, Kahaly GJ. Thyrotropin receptor antibodies and Graves' orbitopathy. J Endocrinol Invest. 2021 Apr;44(4):703-712

Jurk K, Shiravand Y. Platelet Phenotyping and Function Testing in Thrombocytopenia. J Clin Med. 2021 Mar 7;10(5):1114.

Wild J, Wenzel P. Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension. J Mol Med (Berl). 2021 Mar;99(3):315-326.

Jung R, Wild J, Ringen J, Karbach S, Wenzel P. Innate Immune Mechanisms of Arterial Hypertension and Autoimmune Disease. Am J Hypertens. 2021 Mar 11;34(2):143-153.

Squiccimarro E, Jiritano F, Serraino GF, Ten Cate H, Paparella D, Lorusso R. Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support. J Clin Med. 2021 Feb 6;10(4):615.

Nourse J, Danckwardt S. A novel rationale for targeting FXI: Insights from the hemostatic microRNA targetome for emerging anticoagulant strategies. Pharmacol Ther. 2021 Feb;218:107676.

Di Pilla M, Barco S, Sacco C, Barosi G, Lodigiani C. Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis - case report and systematic review of dabigatran use. Vasa. 2021 Feb;50(2):151-156.

Sukumar S, Lämmle B, Cataland SR. Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management. J Clin Med. 2021 Feb 2;10(3):536.

Kakkos SK, Gohel M, Baekgaard N, Bauersachs R, Bellmunt-Montoya S, Black SA, Ten Cate-Hoek AJ, Elalamy I, Enzmann FK, Geroulakos G, Gottsäter A, Hunt BJ, Mansilha A, Nicolaides AN, Sandset PM, Stansby G, Esvs Guidelines Committee, de Borst GJ, Bastos Gonçalves F, Chakfé N, Hinchliffe R, Kolh P, Koncar I, Lindholt JS, Tulamo R, Twine CP, Vermassen F, Wanhainen A, Document Reviewers, De Maeseneer MG, Comerota AJ, Gloviczki P, Kruip MJHA, Monreal M, Prandoni P, Vega de Ceniga M. Editor's Choice - European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis. Eur J Vasc Endovasc Surg. 2021 Jan;61(1):9-82.

Editorials und Fachbeiträge 2021

Konstantinides S, Mavromanoli A, Hobohm L. Diagnostik und Therapie der Lungenembolie [Diagnosis and treatment of pulmonary embolism]. Herz. 2021 Dec;46(6):589-604.

Ruggeri ZM, Ruf W. Is VITT really a HIT. Nat Immunol. 2021 Nov;22(11):1352-1353.

Barco S, Valerio L. Management of acute pulmonary embolism: towards a (truly) global reach. Eur Respir J. 2021 Oct 28;58(4):2101055.

Valerio L, Pleming W, Barco S. Re: Internal Jugular Vein and Cerebral Venous Sinus Infective Thrombophlebitis Detected With 99mTc-HMPAO White Blood Cell Scintigraphy. Clin Nucl Med. 2021 Oct 1;46(10):858-859.

Eichinger S, Morange PE, Cattaneo M, Fretigny M, Rauch A, van Hylckama Vlieg A, Trégouët DA, Ruf W, Levi M, Páramo JA, van der Poll T, Kyrle PA, Garagiola I, Peyvandi F. The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders. Hemasphere. 2021 Sep 10;5(10):e643.

Lämmle B, Rossmann H. Invited commentary to: ADAMTS13 deficiency is associated with abnormal distribution of von Willebrand factor multimers in patients with COVID-19 by Tiffany Pascreau et al. Letter to the Editors-in-Chief, Thrombosis Research. Thromb Res. 2021 Aug;204:141-142.

Ten Cate H, Lämmle B. Special Issue: "The Latest Clinical Advances in Thrombocytopenia". J Clin Med. 2021 Aug 5;10(16):3463.

Ten Cate H. Surviving Covid-19 with Heparin? N Engl J Med. 2021 Aug 26;385(9):845-846. doi: 10.1056/NEJMe2111151.

Barco S, Klok FA. D-dimer testing after anticoagulant discontinuation to predict recurrent venous thromboembolism. Eur J Intern Med. 2021 Jul;89:25-26.

Kakkos SK, Gohel M, Bauersachs R. Re "Is Management of Major Bleeding in Patients Taking Anticoagulants Restricted to Reversal Strategies?". Eur J Vasc Endovasc Surg. 2021 Jul;62(1):142-143.

Konstantinides SV. Thrombotic complications of vaccination against SARS-CoV-2: what pharmacovigilance reports tell us - and what they don't. Eur Respir J. 2021 Jul 1;58(1):2101111.

Prochaska JH, Müller F, Wild PS. Impact of diesel exposure on human health: the saga continues …. Eur J Prev Cardiol. 2020 Apr 9:2047487320915335.

Lämmle B. Endothelial Dysfunction, Atherosclerosis, and Increase of Von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine. Thromb Haemost. 2021 May;121(5):552.

Ten Cate H. Thrombosis: Grand Challenges Ahead! Front Cardiovasc Med. 2021 May 4;8:637005.

Ten Cate H. Colorectal cancer and cardiovascular disease: A thrombo-inflammatory link? Eur J Intern Med. 2021 May;87:15-17.

Barco S, Adenaeuer A, Trinchero A, Falter T, Lackner KJ, Lämmle B, Rossmann H. Comment on "Worldwide Distribution of PK Deficiency: the Defect Seems Mainly Concentrated in West African Countries and the United States". Mediterr J Hematol Infect Dis. 2021 Mar 1;13(1):e2021027.

Barco S, Bates SM, Versteeg HH, Klok FA. COVID-19 in thrombosis research: An editorial perspective. Thromb Res. 2021 May;201:147-150.

Bosmann M. Complement control for COVID-19. https://pubmed.ncbi.nlm.nih.gov/34035117/Sci Immunol. 2021 May 25;6(59):eabj1014.

Pilarczyk K., El Mokhtari N. E., Fleischmann T., Haake N., Konstantinides S. V. Diagnostics and Treatment of acute Pulmonary Embolism. Summary of the current 2019 Guidelines of the European Society of Cardiology. NOTFALL & RETTUNGSMEDIZIN. Feb. 2021

Valerio L, Barco S. Reader comments: Chest surgery in Lemierre syndrome. Proc (Bayl Univ Med Cent). 2021 Jan 11;34(2):336.

Schäfer K, Wenzel P. When big eaters stop feasting: loss of metabolic control in macrophages exacerbates hypertension in obesity. https://pubmed.ncbi.nlm.nih.gov/32298411/Cardiovasc Res. 2021 Jan 21;117(2):351-353.

Gallo A, Valerio L, Barco S. The 2019 European guidelines on pulmonary embolism illustrated with the aid of an exemplary case report. Eur Heart J Case Rep. 2021 Jan 4;5(2):ytaa542.

Ascher S, Wilms E, Pontarollo G, Kiouptsi K, Malinarich F, Kittner JM, Bosmann M, Jurk K, Reinhardt C. Response by Ascher et al to Letter Regarding Article, "Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury". Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):e74-e75.

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Originalartikel 2020

Göbel S, Schwuchow-Thonke S, Jansen T, Karbach S, Emrich T, Gori T, Knies F, Schulz E, Münzel T, Keller K, Wenzel P. Safety of transradial and transfemoral left ventricular compared with transfemoral right ventricular endomyocardial biopsy. ESC Heart Fail. 2020 Dec;7(6):4015-4023

Roncon L, Zuin M, Barco S, Valerio L, Zuliani G, Zonzin P, Konstantinides SV. Incidence of acute pulmonary embolism in COVID-19 patients: Systematic review and meta-analysis.https://pubmed.ncbi.nlm.nih.gov/32958372/ Eur J Intern Med. 2020 Dec;82:29-37

Kyselova A, Elgheznawy A, Wittig I, Heidler J, Mann AW, Ruf W, Fleming I, Randriamboavonjy V. Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes. Basic Res Cardiol. 2020 Dec 1;115(6):75

Keller K, Hobohm L, Münzel T, Lankeit M, Ostad MA. Impact of pulmonary embolism on in-hospital mortality of patients with ischemic stroke.https://pubmed.ncbi.nlm.nih.gov/33059297/ J Neurol Sci. 2020 Dec 15;419:117174

Hobohm L, Becattini C, Ebner M, Lerchbaumer MH, Casazza F, Hasenfuß G, Konstantinides SV, Lankeit M. Definition of tachycardia for risk stratification of pulmonary embolism. Eur J Intern Med. 2020 Dec;82:76-82

Mahmoudpour SH, Valerio L, Douxfils J, Mahan CE, Jankowski M, Quitzau K, Konstantinides SV, Barco S. Potential Drug Interactions between Recombinant Interleukin-2 and Direct Oral Anticoagulants: Indirect Evidence from In Vivo Animal Studies. Hamostaseologie. 2020 Dec;40(5):679-686

Lenz M, Schulz A, Koeck T, Rapp S, Nagler M, Sauer M, Eggebrecht L, Ten Cate V, Panova-Noeva M, Prochaska JH, Lackner KJ, Münzel T, Leineweber K, Wild PS, Andrade-Navarro MA. Missing value imputation in proximity extension assay-based targeted proteomics data. PLoS One. 2020 Dec 14;15(12):e0243487

Zimmer N, Krebs FK, Zimmer S, Mitzel-Rink H, Kumm EJ, Jurk K, Grabbe S, Loquai C, Tuettenberg A. Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis. Cancers (Basel). 2020 Dec 5;12(12):3653

Blessing R, Ahoopai M, Geyer M, Brandt M, Zeiher AM, Münzel T, Wenzel P, Gori T, Dimitriadis Z. The Bioengineered Combo Dual-Therapy CD34 Antibody-Covered Sirolimus-Eluting Coronary Stent in Patients with Chronic Total Occlusion Evaluated by Clinical Outcome and Optical Coherence Tomography Imaging Analysis. J Clin Med. 2020 Dec 28;10(1):80

Ebner M, Guddat N, Keller K, Merten MC, Lerchbaumer MH, Hasenfuß G, Konstantinides SV, Lankeit M. High-sensitivity troponin I for risk stratification in normotensive pulmonary embolism. ERJ Open Res. 2020 Dec 21;6(4):00625-2020

Marini F, Linke J, Binder H. ideal: an R/Bioconductor package for interactive differential expression analysis. BMC Bioinformatics. 2020 Dec 9;21(1):565

Beutel ME, Tibubos AN, Michal M, Wiltink J, Otten D, Werner A, Wild PS, Münzel T, Lackner KJ, Pfeiffer N, König J, Brähler E. Psychosomatische Medizin in der Gutenberg- Gesundheitsstudie (GHS) – Fragestellungen, Messverfahren, ausgewählte Ergebnisse [Psychosomatic medicine in the Gutenberg Health Study (GHS) - research questions, measurement instruments, selected results]. Z Psychosom Med Psychother. 2020 Dec;66(4):355-375

Gaonkar KS, Marini F, Rathi KS, Jain P, Zhu Y, Chimicles NA, Brown MA, Naqvi AS, Zhang B, Storm PB, Maris JM, Raman P, Resnick AC, Strauch K, Taroni JN, Rokita JL. annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions. BMC Bioinformatics. 2020 Dec 14;21(1):577

Geyer M, Keller K, Sotiriou E, Tamm AR, Ruf TF, Kreidel F, Beiras-Fernandez A, Gori T, Schulz E, Münzel T, von Bardeleben RS. Association of transcatheter direct mitral annuloplasty with acute anatomic, haemodynamic, and clinical outcomes in severe mitral valve regurgitation. ESC Heart Fail. 2020 Dec;7(6):3336-3344

Adamopoulos S, Miliopoulos D, Karavidas A, Nikolaou M, Lazaros G, Gkouziouta A, Manginas A, Sevastos G, Karvounis H, Karamitsos TD, Hahalis G, Leopoulou M, Grigoriou K, Balta D, Avgeropoulou CC, Kasiakogias A, Mantas I, Daskalopoulos N, Varvarousis D, Parthenakis FI, Patrianakos AP, Patsilinakos S, Karanikas S, Konstantinides SV, Tziakas DN, Kouvelas N, Ntoliou P, Manolis AJ, Tsinivizov P, Iliodromitis EK, Vrettou AR, Kakouros SN, Douras A, Mpaka N, Makridis P, Karapatsoudi E, Papoulidis N, Sideris A, Parissis JT, Triposkiadis F, Trikas A, Filippatos G. HEllenic Registry on Myocarditis SyndromES on behalf of Hellenic Heart Failure Association: The HERMES-HF Registry. ESC Heart Fail. 2020 Dec;7(6):3676-3684

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 Dec 3;27(6):962-973.e7

Obradovic S, Dzudovic B, Subotic B, Matijasevic J, Mladenovic Z, Bokan A, Trobok J, Pekovic S, Salinger-Martinovic S, Jovanovic L, Kos L, Kovacevic-Preradovic T, Nikolic M, Miloradovic V, Kovacevic-Kuzmanovic A, Zec N, Markovic-Nikolic N, Srdanovic I, Gluvic Z, Kafedzic S, Pancevacki S, Neskovic A, Konstantinides S. Predictive value of heart failure with reduced versus preserved ejection fraction for outcome in pulmonary embolism. ESC Heart Fail. 2020 Dec;7(6):4061-4070

Kyselova A, Siragusa M, Anthes J, Solari FA, Loroch S, Zahedi RP, Walter U, Fleming I, Randriamboavonjy V. Cyclin Y is expressed in Platelets and Modulates Integrin Outside-in Signaling. Int J Mol Sci. 2020 Nov 3;21(21):8239

Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernández-Calvo G, Khoyratty TE, van Grinsven E, González-Hernández S, Nicolás-Ávila JÁ, Vicanolo T, Maccataio A, Benguría A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martín-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sánchez-Cabo F, Nistal-Villán E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A. Co-option of Neutrophil Fates by Tissue Environments. Cell. 2020 Nov 25;183(5):1282-1297.e18

Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 Nov 1;147(9):2564-2577

Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A. The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets. J Thromb Haemost. 2020 Nov;18(11):3002-3012

Saffarzadeh M, Grunz K, Nguyen TS, Lee YK, Kitano M, Danckwardt S, Rodrigues CDS, Weiler H, Reyda S, Ruf W. Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice. Blood Adv. 2020 Nov 24;4(22):5810-5824

Kriechbaum SD, Scherwitz L, Wiedenroth CB, Rudolph F, Wolter JS, Haas M, Fischer-Rasokat U, Rolf A, Hamm CW, Mayer E, Guth S, Keller T, Konstantinides SV, Lankeit M, Liebetrau C. Mid-regional pro-atrial natriuretic peptide and copeptin as indicators of disease severity and therapy response in CTEPH. ERJ Open Res. 2020 Nov 2;6(4):00356-2020

Tanabe S, Fujimura Y, Lämmle B, Kimura T, Isonishi A, Sakai K, Matsumoto M. Stealth thrombosis of brain and kidney in a girl with Upshaw-Schulman syndrome not receiving prophylactic plasma infusions. Int J Hematol. 2020 Nov;112(5):603-604

Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 Nov 1;147(9):2564-2577

Makhoul S, Kumm E, Zhang P, Walter U, Jurk K. The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets. Int J Mol Sci. 2020 Nov 25;21(23):8939

Pielsticker C, Brodde MF, Raum L, Jurk K, Kehrel BE. Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases. Int J Mol Sci. 2020 Nov 23;21(22):8851

Schrage B, Rübsamen N, Schulz A, Münzel T, Pfeiffer N, Wild PS, Beutel M, Schmidtmann I, Lott R, Blankenberg S, Zeller T, Lackner KJ, Karakas M. Iron deficiency is a common disorder in general population and independently predicts all-cause mortality: results from the Gutenberg Health Study. Clin Res Cardiol. 2020 Nov;109(11):1352-1357

Hobohm L, Anušić T, Konstantinides SV, Barco S; HoT-PE Investigators. Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT-PE) Trial. Eur Respir J. 2020 Oct 8;56(4):2000663

Panova-Noeva M, Wagner B, Nagler M, Koeck T, Ten Cate V, Prochaska JH, Heitmeier S, Meyer I, Gerdes C, Laux V, Konstantinides S, Spronk HM, Münzel T, Lackner KJ, Leineweber K, Ten Cate H, Wild PS. Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism - results from clinical observation studies. EBioMedicine. 2020 Oct;60:102978

Hobohm L, Keller K, Valerio L, Ni Ainle F, Klok FA, Münzel T, Kucher N, Lankeit M, Konstantinides SV, Barco S. Fatality rates and use of systemic thrombolysis in pregnant women with pulmonary embolism. ESC Heart Fail. 2020 Oct;7(5):2365-2372

Hendriks SV, Lankeit M, den Exter PL, Zondag W, Brouwer R, Eijsvogel M, Grootenboers MJ, Faber LM, Heller-Baan R, Hofstee HMA, Iglesias Del Sol A, Mairuhu ATA, Melissant CF, Peltenburg HG, van de Ree MA, Serné EH, Konstantinides S, Klok FA, Huisman MV; Vesta Investigators. Uncertain Value of High-sensitive Troponin T for Selecting Patients With Acute Pulmonary Embolism for Outpatient Treatment by Hestia Criteria. Acad Emerg Med. 2020 Oct;27(10):1043-1046

Escher F, Pietsch H, Aleshcheva G, Bock T, Baumeier C, Elsaesser A, Wenzel P, Hamm C, Westenfeld R, Schultheiss M, Gross U, Morawietz L, Schultheiss HP. Detection of viral SARS-CoV-2 genomes and histopathological changes in endomyocardial biopsies. ESC Heart Fail. 2020 Oct;7(5):2440-2447

Emrich T, Hahn F, Fleischmann D, Halfmann MC, Düber C, Varga-Szemes A, Escher F, Pefani E, Münzel T, Schultheiss HP, Kreitner KF, Wenzel P. T1 and T2 mapping to detect chronic inflammation in cardiac magnetic resonance imaging in heart failure with reduced ejection fraction. ESC Heart Fail. 2020 Oct;7(5):2544-2552

Sluka SHM, Stämpfli SF, Akhmedov A, Klein-Rodewald T, Sanz-Moreno A, Horsch M, Grest P, Rothmeier AS, Rathkolb B, Schrewe A, Beckers J, Neff F, Wolf E, Camici GG, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lüscher TF, Ruf W, Tanner FC. Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality. Haematologica. 2020 Oct 1;105(10):2484-2495

Keller K, Göbel S, Ten Cate V, Panova-Noeva M, Eggebrecht L, Nagler M, Coldewey M, Foebel M, Bickel C, Lauterbach M, Espinola-Klein C, Lackner KJ, Cate HT, Münzel T, Wild PS, H Prochaska J. Telemedicine-Based Specialized Care Improves the Outcome of Anticoagulated Individuals with Venous Thromboembolism-Results from the thrombEVAL Study. J Clin Med. 2020 Oct 13;9(10):3281

Sluka SHM, Stämpfli SF, Akhmedov A, Klein-Rodewald T, Sanz-Moreno A, Horsch M, Grest P, Rothmeier AS, Rathkolb B, Schrewe A, Beckers J, Neff F, Wolf E, Camici GG, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lüscher TF, Ruf W, Tanner FC. Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality. Haematologica. 2020 Oct 1;105(10):2484-2495

Corsi G, Nava S, Barco S. Un nuovo strumento per misurare lo stato funzionale globale a lungo termine dei pazienti con malattia da coronavirus 2019: la scala PCFS (Post-COVID-19 Functional Status) [A novel tool to monitor the individual functional status after COVID-19: the Post-COVID-19 Functional Status (PCFS) scale]. G Ital Cardiol (Rome). 2020 Oct;21(10):757

van Paridon PCS, Panova-Noeva M, van Oerle R, Schultz A, Hermanns IM, Prochaska JH, Arnold N, Binder H, Schmidtmann I, Beutel ME, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Thrombin generation in cardiovascular disease and mortality - results from the Gutenberg Health Study. Haematologica. 2020 Sep 1;105(9):2327-2334

Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity. Front Immunol. 2020 Sep 11;11:2189

Wild J, Hobohm L, Münzel T, Wenzel P, Steinbrink K, Karbach S, Keller K. Psoriasis and Its Impact on In-Hospital Outcome in Patients Hospitalized with Acute Kidney Injury.https://pubmed.ncbi.nlm.nih.gov/32957680/ J Clin Med. 2020 Sep 17;9(9):3004

Valerio L, Zuin M, Mahmoudpour SH, Zuliani G, Zonzin P, Barco S, Roncon L. Aggiornamento sui dati relativi alla mortalità da embolia polmonare in Italia (2003-2015) [An update on pulmonary embolism-related mortality in Italy (2003-2015)]. G Ital Cardiol (Rome). 2020 Aug;21(8):639-646

Bell K, Beutgen VM, Nickels S, Lorenz K, Scheller Y, Elbaz H, Peto T, Ponto KA, Schulz A, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N, Grus FH, Schuster AK. Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. J Ophthalmol. 2020 Jul 29;2020:8386160

Kakkar AK, Bauersachs R, Falanga A, Wong J, Kayani G, Kahney A, Hughes R, Levine M. Fundamental Research in Oncology and Thrombosis 2 (FRONTLINE 2): A Follow-Up Survey. Oncologist. 2020 Jul;25(7):e1091-e1097. doi: 10.1634/theoncologist.2019-0676

Bonaca MP, Bauersachs RM, Anand SS, Debus ES, Nehler MR, Patel MR, Fanelli F, Capell WH, Diao L, Jaeger N, Hess CN, Pap AF, Kittelson JM, Gudz I, Mátyás L, Krievins DK, Diaz R, Brodmann M, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR. Rivaroxaban in Peripheral Artery Disease after Revascularization. N Engl J Med. 2020 May 21;382(21):1994-2004

Agnelli G, Becattini C, Meyer G, Muñoz A, Huisman MV, Connors JM, Cohen A, Bauersachs R, Brenner B, Torbicki A, Sueiro MR, Lambert C, Gussoni G, Campanini M, Fontanella A, Vescovo G, Verso M; Caravaggio Investigators. Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer. N Engl J Med. 2020 Apr 23;382(17):1599-1607

Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. Elife. 2020 Apr 21;9:e52511

Schuster AK, Nickels S, Pfeiffer N, Schmidtmann I, Wild PS, Münzel T, Beutel ME, Lackner KJ, Vossmerbaeumer U. 2020. Frequency of cataract surgery and its impact on visual function-results from the German Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 258:2223-2231.

Elbaz H, Schuster AK, Nickels S, Nagler M, Ponto KI, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Peto T. 2020. Epidemiologic Analysis of Asteroid Hyalosis and Associations: The Gutenberg Health Study. Ophthalmology doi:10.1016/j.ophtha.2020.07.008.

Klein EM, Brähler E, Petrowski K, Tibubos AN, Ernst M, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. 2020. The association between recalled parental rearing behavior and depressiveness: a comparison between 1st immigrants and non-immigrants in the population-based Gutenberg Health Study. BMC Psychiatry 20:367.

Reiner IC, Tibubos AN, Werner AM, Ernst M, Brähler E, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, Arnold N, Mahmoudpour SH, Lackner KJ, Pfeiffer N, Beutel ME. 2020. The association of chronic anxiousness with cardiovascular disease and mortality in the community: results from the Gutenberg Health Study. Sci Rep 10:12436.

Bell K, Beutgen VM, Nickels S, Lorenz K, Scheller Y, Elbaz H, Peto T, Ponto KA, Schulz A, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N, Grus FH, Schuster AK. 2020. Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. J Ophthalmol 2020:8386160.

Ernst M, Reiner I, Fiess A, Tibubos AN, Schulz A, Burghardt J, Klein EM, Brähler E, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Michal M, Wiltink J, Beutel ME. 2020. Sex-dependent associations of low birth weight and suicidal ideation in adulthood: a community-based cohort study. Sci Rep 10:12969.

Klein EM, Brähler E, Petrowski K, Tibubos AN, Burghardt J, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. 2020. Recalled parental rearing behavior in adult women and men with depressive and anxiety symptoms: Findings from a community study. Z Psychosom Med Psychother 66:243-258.

Wagner FM, Hoffmann EM, Nickels S, Fiess A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. 2020. Peripapillary Retinal Nerve Fiber Layer Profile in Relation to Refractive Error and Axial Length: Results From the Gutenberg Health Study. Transl Vis Sci Technol 9:35.

Grill A, Kiouptsi K, Karwot C, Jurk K, Reinhardt C. 2020. Evaluation of blood collection methods and anticoagulants for platelet function analyses on C57BL/6J laboratory mice. Platelets 31:981-988.

Hobohm L, Anusic T, Konstantinides SV, Barco S, HoT-PE Investigators. 2020. Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT-PE) Trial. Eur Respir J 56.

Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauss J, Bolisetty S, Luhder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. 2020. Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier. Acta Neuropathol 140:549-567.

Pruszczyk P, Kurnicka K, Ciurzynski M, Hobohm L, Thielmann A, Sobkowicz B, Sawicka E, Kostrubiec M, Ptaszynska-Kopczynska K, Dzikowska-Diduch O, Lichodziejewska B, Lankeit M. 2020. Defining right ventricular dysfunction by echocardiography in normotensive patients with pulmonary embolism. Pol Arch Intern Med 130:741-747.

Krueger I, Gremer L, Mangels L, Klier M, Jurk K, Willbold D, Bock HH, Elvers M. 2020. Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases. Arterioscler Thromb Vasc Biol 40:2391-2403.

Valentin ML, Barco S, Studer G, Clemens R, Kreuzpointner R, Sebastian T, Thalhammer C, Kucher N. 2020. Prevalence of carotid plaque stenosis after head and neck radiotherapy – an observational study of 156 survivors. Vasa doi:10.1024/0301-1526/a000896:1-7.

Kiouptsi K, Jäckel S, Wilms E, Pontarollo G, Winterstein J, Karwot C, Gross K, Jurk K, Reinhardt C. 2020. The Commensal Microbiota Enhances ADP-Triggered Integrin alphaIIbbeta3 Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen. Int J Mol Sci 21.

Valerio L, Zuin M, Mahmoudpour SH, Zuliani G, Zonzin P, Barco S, Roncon L. 2020. [An update on pulmonary embolism-related mortality in Italy (2003-2015)]. G Ital Cardiol (Rome) 21:639-646.

Karbach S, Hobohm L, Wild J, Münzel T, Gori T, Wegner J, Steinbrink K, Wenzel P, Keller K. 2020. Impact of Psoriasis on Mortality Rate and Outcome in Myocardial Infarction. J Am Heart Assoc 9:e016956.

Swieringa F, Solari FA, Pagel O, Beck F, Huang J, Feijge MAH, Jurk K, Korver-Keularts I, Mattheij NJA, Faber J, Pohlenz J, Russo A, Stumpel C, Schrander DE, Zieger B, van der Meijden PEJ, Zahedi RP, Sickmann A, Heemskerk JWM. 2020. Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS. Sci Rep 10:11389.

Lehwald N, Duhme C, Pinchuk I, Kirchner J, Wieferich K, Schmelzle M, Jurk K, Windmoller BA, Hübner W, Homey B, Bode J, Kubitz R, Benhidjeb T, Krüger M, Robson SC, Knoefel WT, Kehrel BE, Schulte Am Esch J. 2020. Platelets Boost Recruitment of CD133(+) Bone Marrow Stem Cells to Endothelium and the Rodent Liver-The Role of P-Selectin/PSGL-1 Interactions. Int J Mol Sci 21.

Efentakis P, Doerschmann H, Witzler C, Siemer S, Nikolaou PE, Kastritis E, Stauber R, Dimopoulos MA, Wenzel P, Andreadou I, Terpos E. 2020. Investigating the Vascular Toxicity Outcomes of the Irreversible Proteasome Inhibitor Carfilzomib. Int J Mol Sci 21.

Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, Karbach S, Wenzel P, Sitnow A, Fleig S, Sparwasser T, Kalinke U, Holzmann B, Haller H, Limbourg FP. 2020. Notch and TLR signaling coordinate monocyte cell fate and inflammation. Elife 9.

Escher F, Pietsch H, Aleshcheva G, Wenzel P, Fruhwald F, Stumpf C, Westermann D, Bauersachs J, Enseleit F, Ruschitzka F, Nägele H, Laugwitz KL, Haake H, Frey N, Brachmann J, Huber K, Braun-Dullaeus RC, Bergmann MW, Strotmann J, Grönefeld G, Krülls-Münch J, Westenfeld R, Skurk C, Landmesser U, Pieske B, Gross UM, Morawietz L, Schultheiss HP. 2020. Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation. J Clin Med 9.

Lagrange J, Finger S, Kossmann S, Garlapati V, Ruf W, Wenzel P. 2020. Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice. Int J Mol Sci 21.

Madhusudhan T, Ghosh S, Wang H, Dong W, Gupta D, Elwakiel A, Stoyanov S, Al-Dabet MM, Krishnan S, Biemann R, Nazir S, Zimmermann S, Mathew A, Gadi I, Rana R, Zeng-Brouwers J, Moeller MJ, Schaefer L, Esmon CT, Kohli S, Reiser J, Rezaie AR, Ruf W, Isermann B. 2020. Podocyte Integrin-beta 3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy. J Am Soc Nephrol 31:1762-1780.

Lagrange J, Wagner B, Nagler M, Ten Cate V, Pallares Robles A, Koeck T, Rapp S, Prochaska JH, Spronk HM, Wenzel P, Ruf W, Ten Cate H, Wild PS, Panova-Noeva M. 2020. Characterization of Thrombin Generation Curve Shape in Presence of Platelets from Acute Venous Thromboembolism Patients. J Clin Med 9.

Wiedenroth Md CB, Rieth Md AJ, Kriechbaum Md S, Ghofrani Md HA, Breithecker Md A, Haas Md M, Roller Md F, Richter Md MJ, Lankeit M, Mielzarek L, Rolf Md A, Hamm Md CW, Mayer Md E, Guth Md S, Liebetrau Md C. 2020. Exercise right heart catheterization before and after balloon pulmonary angioplasty in inoperable patients with chronic thromboembolic pulmonary hypertension. Pulm Circ 10:2045894020917884.

Schnorbus B, Daiber A, Jurk K, Warnke S, Koenig J, Lackner KJ, Münzel T, Gori T. 2020. Effects of clopidogrel vs. prasugrel vs. ticagrelor on endothelial function, inflammatory parameters, and platelet function in patients with acute coronary syndrome undergoing coronary artery stenting: a randomized, blinded, parallel study. Eur Heart J 41:3144-3152. 

Kuntic M, Oelze M, Steven S, Kröller-Schön S, Stamm P, Kalinovic S, Frenis K, Vujacic-Mirski K, Bayo Jimenez MT, Kvandova M, Filippou K, Al Zuabi A, Bruckl V, Hahad O, Daub S, Varveri F, Gori T, Huesmann R, Hoffmann T, Schmidt FP, Keaney JF, Daiber A, Münzel T. 2020. Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2). Eur Heart J 41:2472-2483.

Hopf S, Korb C, Nickels S, Schulz A, Münzel T, Wild PS, Michal M, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. 2020. Prevalence of myopic maculopathy in the German population: results from the Gutenberg health study. Br J Ophthalmol 104:1254-1259.

Roose E, Schelpe AS, Tellier E, Sinkovits G, Joly BS, Dekimpe C, Kaplanski G, Le Besnerais M, Mancini I, Falter T, Von Auer C, Feys HB, Reti M, Rossmann H, Vandenbulcke A, Pareyn I, Voorberg J, Greinacher A, Benhamou Y, Deckmyn H, Fijnheer R, Prohaszka Z, Peyvandi F, Lämmle B, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K. 2020. Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura. Blood 136:353-361.

Hobohm L, Becattini C, Konstantinides SV, Casazza F, Lankeit M. 2020. Validation of a fast prognostic score for risk stratification of normotensive patients with acute pulmonary embolism. Clin Res Cardiol 109:1008-1017.

Steven S, Frenis K, Kalinovic S, Kvandova M, Oelze M, Helmstädter J, Hahad O, Filippou K, Kus K, Trevisan C, Schlüter KD, Boengler K, Chlopicki S, Frauenknecht K, Schulz R, Sorensen M, Daiber A, Kröller-Schön S, Münzel T. 2020. Exacerbation of adverse cardiovascular effects of aircraft noise in an animal model of arterial hypertension. Redox Biol 34:101515. 

Fiess A, Elflein HM, Urschitz MS, Pesudovs K, Münzel T, Wild PS, Michal M, Lackner KJ, Pfeiffer N, Nickels S, Schuster AK. 2020. Prevalence of Strabismus and Its Impact on Vision-Related Quality of Life: Results from the German Population-Based Gutenberg Health Study. Ophthalmology 127:1113-1122.

Döhrmann M, Makhoul S, Gross K, Krause M, Pillitteri D, von Auer C, Walter U, Lutz J, Volf I, Kehrel BE, Jurk K. 2020. CD36-fibrin interaction propagates FXI-dependent thrombin generation of human platelets. FASEB J doi:10.1096/fj.201903189R.

Keller K, Hobohm L, Münzel T, Ostad MA. 2020. Impact of concomitant deep or superficial venous thrombosis of the legs on survival of patients with pulmonary embolism. Int J Cardiol 315:92-98.

Keller K, Hobohm L, Geyer M, Kreidel F, Ostad MA, Lavie CJ, Lankeit M, Konstantinides S, Münzel T, von Bardeleben RS. 2020. Impact of obesity on adverse in-hospital outcomes in patients undergoing percutaneous mitral valve edge-to-edge repair using MitraClip(R) procedure - Results from the German nationwide inpatient sample. Nutr Metab Cardiovasc Dis 30:1365-1374.

Wenzel P, Kopp S, Göbel S, Jansen T, Geyer M, Hahn F, Kreitner KF, Escher F, Schultheiss HP, Münzel T. 2020. Evidence of SARS-CoV-2 mRNA in endomyocardial biopsies of patients with clinically suspected myocarditis tested negative for COVID-19 in nasopharyngeal swab. Cardiovasc Res 116:1661-1663.

Sebastian T, Barco S, Engelberger RP, Spirk D, Schindewolf M, Baumann F, Baumgartner I, Kucher N. 2020. Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. Eur J Vasc Endovasc Surg 60:443-450.

Ascher S, Wilms E, Pontarollo G, Formes H, Bayer F, Müller M, Malinarich F, Grill A, Bosmann M, Saffarzadeh M, Brandao I, Gross K, Kiouptsi K, Kittner JM, Lackner KJ, Jurk K, Reinhardt C. 2020. Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury. Arterioscler Thromb Vasc Biol 40:2279-2292.

Keller K, Hobohm L, Münzel T, Konstantinides SV, Lankeit M. 2020. Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany. ERJ Open Res 6.

Keller K, Hobohm L, Ostad MA, Göbel S, Lankeit M, Konstantinides S, Münzel T, Wenzel P. 2020. Temporal trends and predictors of inhospital death in patients hospitalised for heart failure in Germany. Eur J Prev Cardiol doi:10.1177/2047487320936020:2047487320936020.

Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. 2020. Bacterial polyphosphates interfere with the innate host defense to infection. Nat Commun 11:4035.

Keller P, von Kanel R, Hincapie CA, da Costa BR, Juni P, Erlanger TE, Andina N, Niederhauser C, Lämmle B, Fontana S. 2020. The effects of intravenous iron supplementation on fatigue and general health in non-anemic blood donors with iron deficiency: a randomized placebo-controlled superiority trial. Sci Rep 10:14219.

Soneson C, Marini F, Geier F, Love MI, Stadler MB. 2020. ExploreModelMatrix: Interactive exploration for improved understanding of design matrices and linear models in R. F1000Res 9:512.

Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Hartner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. 2020. Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology. Cell Rep 30:1585-1597 e6. 

Barco S, Sollfrank S, Trinchero A, Adenaeuer A, Abolghasemi H, Conti L, Hauser F, Kremer Hovinga JA, Lackner KJ, Loewecke F, Miloni E, Vazifeh Shiran N, Tomao L, Wuillemin WA, Zieger B, Lämmle B, Rossmann H. Severe plasma prekallikrein deficiency: Clinical characteristics, novel KLKB1 mutations, and estimated prevalence. J Thromb Haemost 2020;18(7):1598-1617.

Kiouptsi K, Pontarollo G, Todorov H, Braun J, Jäckel S, Koeck T, Bayer F, Karwot C, Karpi A, Gerber S, Jansen Y, Wild P, Ruf W, Daiber A, Van Der Vorst E, Weber C, Döring Y, Reinhardt C. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. Gut Microbes 2020;11(6):1809-1823.

Ten Cate V, Eggebrecht L, Schulz A, Panova-Noeva M, Lenz M, Koeck T, Rapp S, Arnold N, Lackner KJ, Konstantinides S, Espinola-Klein C, Münzel T, Prochaska JH, Wild PS. Isolated Pulmonary Embolism Is Associated With a High Risk of Arterial Thrombotic Disease: Results From the VTEval Study. Chest 2020;158(1):341-349.

Schlax J, Wiltink J, Beutel ME, Münzel T, Pfeiffer N, Wild P, Blettner M, Ghaemi Kerahrodi J, Michal M. Symptoms of depersonalization/derealization are independent risk factors for the development or persistence of psychological distress in the general population: Results from the Gutenberg health study. J Affect Disord 2020;273:41-47.

Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, Kucher N, Studt JD, Sacco C, Alexia B, Sandri MT, Barco S, Humanitas C-TF. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020;191:9-14.

Lindhoff-Last E, Herrmann E, Lindau S, Konstantinides S, Grottke O, Nowak-Goettl U, Lucks J, Zydek B, Heymann CV, Birschmann I, Sumnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A. Severe Hemorrhage Associated With Oral Anticoagulants. Dtsch Arztebl Int 2020;117(18):312-319.

Beutel ME, Brähler E, Ernst M, Klein E, Reiner I, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, Hahad O, Konig J, Lackner KJ, Pfeiffer N, Tibubos AN. Noise annoyance predicts symptoms of depression, anxiety and sleep disturbance 5 years later. Findings from the Gutenberg Health Study. Eur J Public Health 2020;30(3):516-521.

Keller K, Hobohm L, Barco S, Schmidtmann I, Münzel T, Engelhardt M, Goldhofer M, Konstantinides SV, Drees P. Venous thromboembolism in patients hospitalized for hip joint replacement surgery. Thromb Res 2020;190:1-7. 

Romero Starke K, Hegewald J, Schulz A, Garthus-Niegel S, Nubling M, Wild PS, Arnold N, Latza U, Jankowiak S, Liebers F, Rossnagel K, Riechmann-Wolf M, Letzel S, Beutel M, Pfeiffer N, Lackner K, Münzel T, Seidler A. Cardiovascular health outcomes of mobbing at work: results of the population-based, five-year follow-up of the Gutenberg health study. J Occup Med Toxicol 2020;15:15.

Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Cell 2020;181(5):1080-1096 e1019

Kroone C, Vos M, Rademakers T, Kuijpers M, Hoogenboezem M, van Buul J, Heemskerk JWM, Ruf W, van Hylckama Vlieg A, Versteeg HH, Goumans MJ, de Vries CJM, Kurakula K, Consortium I. LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis. Haematologica 2020;105(6):1677-1685.

Boon G, Barco S, Bertoletti L, Ghanima W, Huisman MV, Kahn SR, Noble S, Prandoni P, Rosovsky RP, Sista AK, Siegerink B, Klok FA. Measuring functional limitations after venous thromboembolism: Optimization of the Post-VTE Functional Status (PVFS) Scale. Thromb Res 2020;190:45-51.

Nayor M, Short MI, Rasheed H, Lin H, Jonasson C, Yang Q, Hveem K, Felix JF, Morrison AC, Wild PS, Morley MP, Cappola TP, Benson MD, Group CH-HFW, Consortium CH-E, Ngo D, Sinha S, Keyes MJ, Shen D, Wang TJ, Larson MG, Brumpton BM, Gerszten RE, Omland T, Vasan RS. Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits. Circ Heart Fail 2020;13(5):e006749.

Kaemmerer H, Gorenflo M, Huscher D, Pittrow D, Apitz C, […] Konstantinides S, […] Wilkens H, Wirtz H, Diller GP, Grunig E, Rosenkranz S. Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry. J Clin Med 2020;9(5).

Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. Elife 2020;9.

Nickels S, Blom HJ, Schulz A, Joachimsen L, Münzel T, Wild PS, Beutel ME, Blettner M, Lackner KJ, Pfeiffer N, Lagreze WA. No evidence for an association of plasma homocysteine levels and refractive error - Results from the population-based Gutenberg Health Study (GHS). PLoS One 2020;15(4):e0231011.

Ernst M, Brähler E, Klein EM, Jünger C, Wild PS, Faber J, Schneider A, Beutel ME. What's past is prologue: Recalled parenting styles are associated with childhood cancer survivors' mental health outcomes more than 25 years after diagnosis. Soc Sci Med 2020;252:112916.

Rezapour J, Schuster AK, Nickels S, Korb CA, Elbaz H, Peto T, Michal M, Münzel T, Wild PS, König J, Lackner K, Schulz A, Pfeiffer N, Beutel ME. Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort. Sci Rep 2020;10(1):4816.

Lauterbach M, Uhrich E, Eggebrecht L, Göbel S, Panova-Noeva M, Nagler M, Ten Cate V, Bickel C, Espinola-Klein C, Münzel T, Wild PS, Prochaska JH. Specialized Management of Oral Anticoagulation Therapy Improves Outcome in Patients with Chronic Renal Insufficiency. J Clin Med 2020;9(3).

White RJ, Jerjes-Sanchez C, Bohns Meyer GM, Pulido T, Sepulveda P, Wang KY, Grunig E, Hiremath S, Yu Z, Gangcheng Z, Yip WLJ, Zhang S, Khan A, Deng CQ, Grover R, Tapson VF, Freedom-Ev Investigators. Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial. Am J Respir Crit Care Med 2020;201(6):707-717.

Ernst M, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. The desire for children among adult survivors of childhood cancer: Psychometric evaluation of a cancer-specific questionnaire and relations with sociodemographic and psychological characteristics. Psychooncology 2020;29(3):485-492.

Schuster AK, Kluck AK, Korb CA, Stoffelns B, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N. Characteristics and pathologies of the vitreo-macular interface-results from the Gutenberg Health Study. Acta Ophthalmol 2020;98(3):e273-e281.

Keller K, Hobohm L, Wenzel P, Münzel T, Espinola-Klein C, Ostad MA. Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients. Heart Rhythm 2020;17(3):383-390. 

Barco S, Mahmoudpour SH, Valerio L, Klok FA, Münzel T, Middeldorp S, Ageno W, Cohen AT, Hunt BJ, Konstantinides SV. Trends in mortality related to pulmonary embolism in the European Region, 2000-15: analysis of vital registration data from the WHO Mortality Database. Lancet Respir Med 2020;8(3):277-287.

Todorov H, Kollar B, Bayer F, Brandao I, Mann A, Mohr J, Pontarollo G, Formes H, Stauber R, Kittner JM, Endres K, Watzer B, Nockher WA, Sommer F, Gerber S, Reinhardt C. alpha-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine. Nutrients 2020;12(3).

Amezquita RA, Lun ATL, Becht E, Carey VJ, Carpp LN, Geistlinger L, Marini F, Rue-Albrecht K, Risso D, Soneson C, Waldron L, Pages H, Smith ML, Huber W, Morgan M, Gottardo R, Hicks SC. Orchestrating single-cell analysis with Bioconductor. Nat Methods 2020;17(2):137-145.

Schuster AK, Leuschner A, Feretos C, Blumenstein P, Troebs SO, Schwuchow S, Schulz A, Nickels S, Mirshahi A, Blettner M, Beutel ME, Lackner KJ, Münzel T, Pfeiffer N, Wild PS. Choroidal thickness is associated with cardiovascular risk factors and cardiac health: the Gutenberg Health Study. Clin Res Cardiol 2020;109(2):172-182.

Hampel U, Schuster AK, Nickels S, Schulz A, Lackner KJ, Münzel T, Wild PS, Beutel M, Schmidtmann I, Pfeiffer N. Schirmer test results: are they associated with topical or systemic medication? Ocul Surf 2020;18(1):141-147.

Helmstädter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Kröller-Schön S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Münzel T, Daiber A, Steven S. Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension. Arterioscler Thromb Vasc Biol 2020;40(1):145-158.

Gresele P, Orsini S, Noris P, Falcinelli E, Alessi MC, Bury L, Borhany M, Santoro C, Glembotsky AC, Cid AR, Tosetto A, De Candia E, Fontana P, Guglielmini G, Pecci A, Bat-Val study investigators. Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC. J Thromb Haemost 2020;18(3):732-739. 

Hollerbach A, Müller-Calleja N, Canisius A, Orning C, Lackner KJ. Induction of tissue factor expression by anti-beta2-glycoprotein I is mediated by tumor necrosis factor alpha. J Thromb Thrombolysis 2020;49(2):228-234.

Mufazalov IA, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, Tang Y, Schüler R, Eich C, Wunderlich FT, Karbach SH, Bluestone JA, Korn T, Waisman A. Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R alpha-Chain Expression. J Immunol 2020;204(4):747-751.

Ernst M, Brähler E, Wild PS, Jünger C, Faber J, Schneider A, Beutel ME. Risk factors for suicidal ideation in a large, registry-based sample of adult long-term childhood cancer survivors. J Affect Disord 2020;265:351-356.

Burghardt J, Tibubos AN, Otten D, Brähler E, Binder H, Grabe H, Kruse J, Ladwig KH, Schomerus G, Wild PS, Beutel ME. A multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany. BMJ Open 2020;10(2):e034220.

Münzel T, Steven S, Hahad O, Daiber A. The sixth sense is involved in noise-induced stress responses and vascular inflammation: evidence for heightened amygdalar activity in response to transport noise in man. Eur Heart J 2020;41(6):783-785.

Kumm EJ, Pagel O, Gambaryan S, Walter U, Zahedi RP, Smolenski A, Jurk K. The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets. Cells 2020;9(2).

Efentakis P, Varela A, Chavdoula E, Sigala F, Sanoudou D, Tenta R, Gioti K, Kostomitsopoulos N, Papapetropoulos A, Tasouli A, Farmakis D, Davos CH, Klinakis A, Suter T, Cokkinos DV, Iliodromitis EK, Wenzel P, Andreadou I. Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy. Cardiovasc Res 2020;116(3):576-591.

Chen W, Werner F, Illerhaus A, Knopp T, Völker K, Potapenko T, Hofmann U, Frantz S, Baba HA, Rösch M, Zernecke A, Karbach S, Wenzel P, Kuhn M. Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide). Arterioscler Thromb Vasc Biol 2020;40(3):682-696.

Meyer M, Wild J, Hirschmann M, Dimitriadis Z, Münzel T, Gori T, Wenzel P. Predictors for Target Vessel Failure after Recanalization of Chronic Total Occlusions in Patients Undergoing Surveillance Coronary Angiography. J Clin Med 2020;9(1).

Witkowski M, Witkowski M, Saffarzadeh M, Friebel J, Tabaraie T, Ta Bao L, Chakraborty A, Dorner A, Stratmann B, Tschoepe D, Winter SJ, Krueger A, Ruf W, Landmesser U, Rauch U. Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes. Cardiovasc Diabetol 2020;19(1):20.

Krieg VJ, Hobohm L, Liebetrau C, Guth S, Kölmel S, Troidl C, Mayer E, Konstantinides SV, Wiedenroth CB, Lankeit M. Risk factors for chronic thromboembolic pulmonary hypertension - Importance of thyroid disease and function. Thromb Res 2020;185:20-26.

Keller K, Hobohm L, Ebner M, Kresoja KP, Münzel T, Konstantinides SV, Lankeit M. Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany. Eur Heart J 2020;41(4):522-529.

Ebner M, Kresoja KP, Keller K, Hobohm L, Rogge NIJ, Hasenfuss G, Pieske B, Konstantinides SV, Lankeit M. Temporal trends in management and outcome of pulmonary embolism: a single-centre experience. Clin Res Cardiol 2020;109(1):67-77.

Bochenek ML, Leidinger C, Rosinus NS, Gogiraju R, Guth S, Hobohm L, Jurk K, Mayer E, Münzel T, Lankeit M, Bosmann M, Konstantinides S, Schäfer K. Activated Endothelial TGFbeta1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension. Circ Res 2020;126(2):162-181.

Ebner M, Rogge NIJ, Parwani AS, Sentler C, Lerchbaumer MH, Pieske B, Konstantinides SV, Hasenfuss G, Wachter R, Lankeit M. Atrial fibrillation is frequent but does not affect risk stratification in pulmonary embolism. J Intern Med 2020;287(1):100-113.

Barco S, Schmidtmann I, Ageno W, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jimenez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Manolis A, Meyer A, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Westerweel PE, Wild PS, Konstantinides SV, Lankeit M, HoT-PE Investigators. Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multicentre single-arm clinical trial. Eur Heart J 2020;41(4):509-518.

Barco S, Klok FA, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Simonneau G, Delcroix M, Lang IM. Sex-specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry. J Thromb Haemost 2020;18(1):151-161.

Visser M, van Oerle R, Ten Cate H, Laux V, Mackman N, Heitmeier S, Spronk HMH. Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX. Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):103-111

Weitz JI, Bauersachs R, Becker B, Berkowitz SD, Freitas MCS, Lassen MR, Metzig C, Raskob GE. Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: The FOXTROT Randomized Clinical Trial. JAMA. 2020 Jan 14;323(2):130-139

Reviews 2020

Ruf W, Graf C. 2020. Coagulation signaling and cancer immunotherapy. Thromb Res 191 Suppl 1:S106-S111.

Valerio L, Corsi G, Sebastian T, Barco S. Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry. Thromb Res. 2020 Dec;196:494-499

Schulman S, Hu Y, Konstantinides S. Venous Thromboembolism in COVID-19. Thromb Haemost. 2020 Dec;120(12):1642-1653

Hart C, Bauersachs R, Scholz U, Zotz R, Bergmann F, Rott H, Linnemann B. Prevention of Venous Thromboembolism during Pregnancy and the Puerperium with a Special Focus on Women with Hereditary Thrombophilia or Prior VTE-Position Paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH). Hamostaseologie. 2020 Dec;40(5):572-590

Ebner M, Lankeit M. 2020. [Antithrombotic Treatment of Pulmonary Embolism]. Dtsch Med Wochenschr 145:970-977.

Lämmle B. Clinical Problem Solving and Using New Paths in the Laboratory: Learning from Case Studies. Hamostaseologie. 2020 Nov;40(4):414-419

Geyer M, Wild J, Münzel T, Gori T, Wenzel P. State of the Art-High-Sensitivity Troponins in Acute Coronary Syndromes. Cardiol Clin. 2020 Nov;38(4):471-479

Bikdeli B, Madhavan MV, Gupta A, Jimenez D, Burton JR, Der Nigoghossian C, Chuich T, Nouri SN, Dreyfus I, Driggin E, [...], Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global, Covid-Thrombosis Collaborative Group. 2020. Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research. Thromb Haemost 120:1004-1024.

Konstantinides S, Meyer G. 2020. Management of acute pulmonary embolism 2019: what is new in the updated European guidelines? Intern Emerg Med 15:957-966. 

Wild J, Wegner J, Karbach S. Von der Haut zum Gefäßsystem – Psoriasis und das kardiovaskuläre Risiko. Der Kardiologe 14, 205–211

Hobohm L, Keller K, Münzel T, Gori T, Konstantinides SV. EkoSonic® endovascular system and other catheter-directed treatment reperfusion strategies for acute pulmonary embolism: overview of efficacy and safety outcomes. Expert Rev Med Devices. 2020 Aug;17(8):739-749

Escher R, Breakey N, Lämmle B. Severe COVID-19 infection associated with endothelial activation. Thromb Res 2020;190:62.

Göbel S, Hobohm L, Ostad MA, Lavie CJ, Gori T, Münzel T, Wenzel P, Keller K. Sex-specific differences drive temporal trends and outcomes of patients hospitalized for heart failure in Germany. Prog Cardiovasc Dis. 2020 Sep-Oct;63(5):591-598

Valerio L, Riva N. Head, Neck, and Abdominopelvic Septic Thrombophlebitis: Current Evidence and Challenges in Diagnosis and Treatment. Hamostaseologie. 2020 Aug;40(3):301-310

Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Giri J, Cushman M, Quere I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Caprini JA, Tafur AJ, Burton JR, Francese DP, Wang EY, Falanga A, McLintock C, Hunt BJ, Spyropoulos AC, Barnes GD, Eikelboom JW, Weinberg I, Schulman S, Carrier M, Piazza G, Beckman JA, Steg PG, Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global Covid-19 Thrombosis Collaborative Group EbtINE, the Iua SbtESCWGoPC, Right Ventricular F. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol 2020;75(23):2950-2973.

Ebner M, Lankeit M. [Update diagnosis and therapeutic management of pulmonary embolism]. Dtsch Med Wochenschr 2020;145(11):710-715.

Nourse J, Spada S, Danckwardt S. Emerging Roles of RNA 3'-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules 2020;10(6). 

Kiouptsi K, Reinhardt C. Physiological Roles of the von Willebrand Factor-Factor VIII Interaction. Subcell Biochem 2020;94:437-464.

Lutz J, Jurk K. Platelets in Advanced Chronic Kidney Disease: Two Sides of the Coin. Semin Thromb Hemost 2020;46(3):342-356.

Bauersachs R, Khorana AA, Lee AYY, Soff G. Cancer-associated venous thromboembolism: Treatment and prevention with rivaroxaban. Res Pract Thromb Haemost. 2020 Apr 4;4(4):532-549

Stakos D, Skendros P, Konstantinides S, Ritis K. Traps N' Clots: NET-Mediated Thrombosis and Related Diseases. Thromb Haemost 2020;120(3):373-383.

Barco S, Sebastian T. Death from, with, and without pulmonary embolism. Eur J Intern Med 2020;73:25-26.

Ward CM, Andrews RK, ISTH State of the Art Speakers. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia. Res Pract Thromb Haemost 2019;3(3):431-497.

Pontarollo G, Mann A, Brandao I, Malinarich F, Schöpf M, Reinhardt C. Protease-activated receptor signaling in intestinal permeability regulation. FEBS J 2020;287(4):645-658.

Pontarollo G, Kiouptsi K, Reinhardt C. A holobiont view on thrombosis: unravelling the microbiota's influence on arterial thrombus growth. Microb Cell 2020;7(1):28-31.

Bauersachs RM, Herold J. Oral Anticoagulation in the Elderly and Frail. Hamostaseologie. 2020 Feb;40(1):74-83

Meyer G, Konstantinides S. Should oral anticoagulation be discontinued after 3 months in the setting of a first high-risk pulmonary embolism secondary to a major transient/reversible risk factor? Eur Respir J 2020;55(1).

Pruszczyk P, Konstantinides S. Where to treat patients with acute pulmonary embolism? Kardiol Pol 2020;78(1):15-19.

Editorials und Fachbeiträge 2020

Konstantinides SV. Home treatment of pulmonary embolism: are all the questions answered now after the HOME-PE trial? Cardiovasc Res. 2020 Nov 1;116(13):e179-e181

Jara-Palomares L, Solier-López A, Russo M, Suñer M, González-Roncero F, Peters-Sengers H, Middeldorp S, Bemelman FJ, Barco S. Thromboprophylaxis after renal transplantation and patient risk stratification: The case of mTOR inhibitors. Thromb Res. 2020 Nov;195:100-102

Zuin M, Barco S, Zuliani G, Roncon L. Management of high-risk pulmonary embolism in an "unstable medical environment": Not only a matter of hemodynamic. Thromb Res. 2020 Nov;195:193-194

Valerio L, Barco S. 2020. Risk stratification of normotensive pulmonary embolism: One more ride on the merry-go-round. Eur Heart J Acute Cardiovasc Care 9:256-258.

Barco S. 2020. The Millennial Generation of Thrombosis and Hemostasis. Hamostaseologie 40:259-261

Klok FA, Barco S. Anticoagulation in splanchnic and cerebral vein thrombosis: Still groping in the dark. Res Pract Thromb Haemost. 2020 Sep 14;4(7):1080-1082

Bosmann M. 2020. Complement Activation during Critical Illness: Current Findings and an Outlook in the Era of COVID-19. Am J Respir Crit Care Med 202:163-165.

Klok FA, Boon G, Barco S, Endres M, Geelhoed JJM, Knauss S, Rezek SA, Spruit MA, Vehreschild J, Siegerink B. 2020. The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19. Eur Respir J 56.

Schulman S, Konstantinides S, Hu Y, Tang LV. 2020. Venous Thromboembolic Diseases: Diagnosis, Management and Thrombophilia Testing: Observations on NICE Guideline [NG158]. Thromb Haemost 120:1143-1146.

Barco S, Konstantinides SV, Investigators C-T. 2020. Thrombosis and thromboembolism related to COVID-19: A clarion call for obtaining solid estimates from large-scale multicenter data. Res Pract Thromb Haemost 4:741-743. 

Konstantinides SV. 2020. Thrombosis and Thromboembolism Related to COVID-19: Increase the Level of Awareness, Lower the Threshold of Suspicion, and Keep Following the Guidelines. JACC Case Rep 2:1388-1390.

Barco S, Münger M, Sebastian T, Kucher N. Reperfusion treatment for high-risk pulmonary embolism associated with COVID-19. Vasa 2020;49(4):257-258.

Konstantinides S, Lankeit M, Erbel C, Tiefenbacher C. Comments on the guidelines (2019) of the European Society of Cardiology on the management of acute pulmonary embolism With the collaboration of the European Respiratory Society (ERS). European Society of Cardiology zum Management der akuten Lungenembolie. Kardiologe (2020). doi.org/10.1007/s12181-020-00389-x  

Wild PS, Dimmeler S, Eschenhagen T. An epidemiological study exploring a possible impact of treatment with ACE inhibitors or angiotensin receptor blockers on ACE2 plasma concentrations. J Mol Cell Cardiol 2020;141:108-109.

Konstantinides SV. The optimal imaging test for diagnosis of acute pulmonary embolism: a second chance for lung scintigraphy? Eur Respir J 2020;55(6).

Escher R, Breakey N, Lämmle B. ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients. Thromb Res 2020;192:174-175.

Tziakas DN, Pavlaki M, Chalikias G, Konstantinides SV, Schäfer K. Letter by Tziakas et al Regarding Article, "Aortic Valve Stenosis: From Basic Mechanisms to Novel Therapeutic Targets". Arterioscler Thromb Vasc Biol 2020;40(6):e180-e181.

Konstantinides SV. Chronic thromboembolic disease following pulmonary embolism: more work ahead. Eur Respir J 2020;55(4).

Ruf W. TRIF turns the switch for DIC in sepsis. Blood 2020;135(14):1073-1074.

Barco S, Konstantinides SV. Predicting Venous Thromboembolism in Primary Care. Thromb Haemost 2020;120(4):531-533.

d'Alessandro E, Becker C, Bergmeier W, Bode C, Bourne JH, Brown H, Buller HR, Ten Cate-Hoek AJ, Ten Cate V, van Cauteren YJM, Cheung YFH, Cleuren A, Coenen D, Crijns H, de Simone I, Dolleman SC, Klein CE, Fernandez DI, Granneman L, van THA, Henke P, Henskens YMC, Huang J, Jennings LK, Jooss N, Karel M, van den Kerkhof D, Klok FA, Kremers B, Lämmle B, Leader A, Lundstrom A, Mackman N, Mannucci PM, Maqsood Z, van der Meijden PEJ, van Moorsel M, Moran LA, Morser J, van Mourik M, Navarro S, Neagoe RAI, Olie RH, van Paridon P, Posma J, Provenzale I, Reitsma PH, Scaf B, Schurgers L, Seelig J, Siegbahn A, Siegerink B, Soehnlein O, Soriano EM, Sowa MA, Spronk HMH, Storey RF, Tantiwong C, Veninga A, Wang X, Watson SP, Weitz J, Zeerleder SS, Ten Cate H, Scientific Reviewer C. Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2020;120(4):538-564.

Coppo P, Lämmle B. Animal models of thrombotic thrombocytopenic purpura: the tales from zebrafish. Haematologica 2020;105(4):861-863.

Konstantinides S. 2019 ESC guidelines on pulmonary embolism: Novelties and unanswered questions. Eur J Intern Med 2020;74:1-4.

Knopp T, Karbach S, Wenzel P. Myeloid Cells to the Rescue: Improving Thrombus Resolution. Thromb Haemost 2020;120(2):197-198.

Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ni Ainle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, ESC Scientific Document Group. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41(4):543-603.

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Originalartikel 2019

• Beutel ME, Brähler E, Wiltink J, Kerahrodi JG, Burghardt J, Michal M, Schulz A, Wild PS, Münzel T, Schmidtmann I, Lackner KJ, Pfeiffer N, Borta A, Tibubos AN. New onset of depression in aging women and men: contributions of social, psychological, behavioral, and somatic predictors in the community. Psychol Med 2019;49(7):1148-1155.
• Kozhuharov N, Goudev A, Flores D, [...], Wenzel P, [...], Münzel T, Erne P, Mueller C, GALACTIC Investigators. Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure: The GALACTIC Randomized Clinical Trial. JAMA 2019;322(23):2292-2302.
• Fiess A, Elbaz H, Korb CA, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N, Schuster AK. Low Birth Weight Is Linked to Age-Related Macular Degeneration: Results From the Population-Based Gutenberg Health Study (GHS). Invest Ophthalmol Vis Sci 2019;60(14):4943-4950.
• Tibubos AN, Brähler E, Ernst M, Baumgarten C, Wiltink J, Burghardt J, Michal M, Ghaemi Kerahrodi J, Schulz A, Wild PS, Münzel T, Schmidtmann I, Lackner KJ, Pfeiffer N, Borta A, Beutel ME. Course of depressive symptoms in men and women: differential effects of social, psychological, behavioral and somatic predictors. Sci Rep 2019;9(1):18929.
• Ghaemi Kerahrodi J, Brähler E, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, Toenges G, Lackner KJ, Pfeiffer N, Beutel ME. Association between medicated obstructive pulmonary disease, depression and subjective health: results from the population-based Gutenberg Health Study. Sci Rep 2019;9(1):20252.
• Alflen A, Aranda Lopez P, Hartmann AK, Maxeiner J, Bosmann M, Sharma A, Platten J, Ries F, Beckert H, Ruf W, Radsak MP. Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis. Immunobiology 2019:151867.
• Brunner FJ, Waldeyer C, Ojeda F, Salomaa V, Kee F, Sans S, Thorand B, Giampaoli S, Brambilla P, Tunstall-Pedoe H, Moitry M, Iacoviello L, Veronesi G, Grassi G, Mathiesen EB, Soderberg S, Linneberg A, Brenner H, Amouyel P, Ferrieres J, Tamosiunas A, Nikitin YP, Drygas W, Melander O, Jockel KH, Leistner DM, Shaw JE, Panagiotakos DB, Simons LA, Kavousi M, Vasan RS, Dullaart RPF, Wannamethee SG, Riserus U, Shea S, de Lemos JA, Omland T, Kuulasmaa K, Landmesser U, Blankenberg S, Multinational Cardiovascular Risk Consortium. Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. Lancet 2019;394(10215):2173-2183.
• Makhoul S, Dörschel S, Gambaryan S, Walter U, Jurk K. Feedback Regulation of Syk by Protein Kinase C in Human Platelets. Int J Mol Sci 2019;21(1).
• Schütz E, Gogiraju R, Pavlaki M, Drosos I, Georgiadis GS, Argyriou C, Rim Ben Hallou A, Konstantinou F, Mikroulis D, Schüler R, Bochenek ML, Gachkar S, Buschmann K, Lankeit M, Karbach SH, Münzel T, Tziakas D, Konstantinides S, Schäfer K. Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation. Int J Mol Sci 2019;21(1).
• Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S, Marini F, Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D, Berger M, Bopp T, Tackenberg B, Huber M. IL-17(+) CD8(+) T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nat Commun 2019;10(1):5722. 
• Panova-Noeva M, Wagner B, Nagler M, Arnold N, Prochaska JH, Eckerle S, Spronk HM, Merzenich H, Wingerter A, Schneider A, Danckwardt S, Ten Cate H, Faber J, Wild PS. Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample. Sci Rep 2019;9(1):20090.
• Triantafyllias K, de Blasi M, Lutgendorf F, Cavagna L, Stortz M, Weinmann-Menke J, Konstantinides S, Galle PR, Schwarting A. High cardiovascular risk in mixed connective tissue disease: evaluation of macrovascular involvement and its predictors by aortic pulse wave velocity. Clin Exp Rheumatol 2019;37(6):994-1002.
• Münzel T, Hahad O, Gori T, Hollmann S, Arnold N, Prochaska JH, Schulz A, Beutel M, Pfeiffer N, Schmidtmann I, Lackner KJ, Keaney JF, Jr., Wild PS. Heart rate, mortality, and the relation with clinical and subclinical cardiovascular diseases: results from the Gutenberg Health Study. Clin Res Cardiol 2019;108(12):1313-1323.
• Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B, Nelson CP, Bastiaenen R, De Bortoli M, Rossini A, Deisenhofer I, Stark K, Assa S, Braund PS, Cabrera C, Dominiczak AF, Gogele M, Hall LM, Ikram MA, Kavousi M, Lackner KJ, Lifelines Cohort S, Müller C, Münzel T, Nauck M, Padmanabhan S, Pfeiffer N, Spector TD, Uitterlinden AG, Verweij N, Volker U, Warren HR, Zafar M, Felix SB, Kors JA, Snieder H, Munroe PB, Pattaro C, Fuchsberger C, Schmidt G, Nolte IM, Schunkert H, Pramstaller PP, Wild PS, van der Harst P, Stricker BH, Schnabel RB, Samani NJ, Hengstenberg C, Dorr M, Behr ER, Reinhard W. KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI Insight 2019;4(23).
• Sebastian T, Spirk D, Engelberger RP, Dopheide JF, Baumann FA, Barco S, Spescha R, Leeger C, Kucher N. Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thromb Haemost 2019;119(12):2064-2073.
• Makhoul S, Panova-Noeva M, Regnault V, Ruf W, Wenzel P, Lagrange J. Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography. J Clin Med 2019;8(11).
• Elflein HM, Schuster AK, Pitz S, Hardt J, Nickels S, Münzel T, Wild PS, Beutel ME, Blettner M, Lackner KJ, Pfeiffer N, Unterrainer JM. Intact Visuospatial Cognition in Amblyopia: Results From the Gutenberg Health Study. J Pediatr Ophthalmol Strabismus 2019;56(6):397-401.
• Labenz C, Prochaska JH, Huber Y, Nagel M, Straub BK, Wild P, Galle PR, Schattenberg JM. Cardiovascular Risk Categories in Patients With Nonalcoholic Fatty Liver Disease and the Role of Low-Density Lipoprotein Cholesterol. Hepatol Commun 2019;3(11):1472-1481.
• Kieback AG, Espinola-Klein C, Lamina C, Moebus S, Tiller D, Lorbeer R, Schulz A, Meisinger C, Medenwald D, Erbel R, Kluttig A, Wild PS, Kronenberg F, Kröger K, Ittermann T, Dörr M. One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects. PLoS One 2019;14(11):e0224608.
• Hahad O, Wild PS, Prochaska JH, Schulz A, Hermanns I, Lackner KJ, Pfeiffer N, Schmidtmann I, Beutel M, Gori T, Deanfield JE, Münzel T. Endothelial Function Assessed by Digital Volume Plethysmography Predicts the Development and Progression of Type 2 Diabetes Mellitus. J Am Heart Assoc 2019;8(20):e012509.
• Lowres N, Olivier J, Chao TF, Chen SA, Chen Y, Diederichsen A, Fitzmaurice DA, Gomez-Doblas JJ, Harbison J, Healey JS, Hobbs FDR, Kaasenbrood F, Keen W, Lee VW, Lindholt JS, Lip GYH, Mairesse GH, Mant J, Martin JW, Martin-Rioboo E, McManus DD, Muniz J, Münzel T, Nakamya J, Neubeck L, Orchard JJ, Perula de Torres LA, Proietti M, Quinn FR, Roalfe AK, Sandhu RK, Schnabel RB, Smyth B, Soni A, Tieleman R, Wang J, Wild PS, Yan BP, Freedman B. Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals. PLoS Med 2019;16(9):e1002903.
• Ernst M, Wiltink J, Tibubos AN, Brähler E, Schulz A, Wild PS, Burghardt J, Münzel T, König J, Lackner K, Pfeiffer N, Michal M, Beutel ME. Linking cancer and mental health in men and women in a representative community sample. J Psychosom Res 2019;124:109760.
• Neumann JT, Twerenbold R, Ojeda F, Sorensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jorgensen T, Soderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renne T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S. Application of High-Sensitivity Troponin in Suspected Myocardial Infarction. N Engl J Med 2019;380(26):2529-2540.
• Schlax J, Jünger C, Beutel ME, Münzel T, Pfeiffer N, Wild P, Blettner M, Kerahrodi JG, Wiltink J, Michal M. Income and education predict elevated depressive symptoms in the general population: results from the Gutenberg health study. BMC Public Health 2019;19(1):430.
• Herzog J, Schmidt FP, Hahad O, Mahmoudpour SH, Mangold AK, Garcia Andreo P, Prochaska J, Koeck T, Wild PS, Sorensen M, Daiber A, Münzel T. Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects. Basic Res Cardiol 2019;114(6):46.
• Fujimura Y, Lämmle B, Tanabe S, Sakai K, Kimura T, Kokame K, Miyata T, Takahashi Y, Taniguchi S, Matsumoto M. Patent ductus arteriosus generates neonatal hemolytic jaundice with thrombocytopenia in Upshaw-Schulman syndrome. Blood Adv 2019;3(21):3191-3195.
• Makhoul S, Trabold K, Gambaryan S, Tenzer S, Pillitteri D, Walter U, Jurk K. cAMP- and cGMP-elevating agents inhibit GPIbalpha-mediated aggregation but not GPIbalpha-stimulated Syk activation in human platelets. Cell Commun Signal 2019;17(1):122.
• Elbaz H, Schulz A, Ponto KA, Nickels S, Pfeiffer N, Mirshahi A, Peto T. Posterior segment eye lesions: prevalence and associations with ocular and systemic parameters: results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 2019;257(10):2127-2135.
• Wild J, Schüler R, Knopp T, Molitor M, Kossmann S, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH. Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation. Int J Mol Sci 2019;20(17).
• Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Roth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology. Nat Commun 2019;10(1):4877.
• Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. MBio 2019;10(5).

• Müller-Calleja N, Hollerbach A, Ritter S, Pedrosa DG, Strand D, Graf C, Reinhardt C, Strand S, Poncelet P, Griffin JH, Lackner KJ, Ruf W. Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis. Blood 2019;134(14):1119-1131.

• Grothusen C., Lankeit M., Olsson K., Panholzer B., Haneya A., Cremer J. Acute pulmonary embolism. Diagnostics and treatment including surgical treatment options. ZEITSCHRIFT FUR HERZ THORAX UND GEFASSCHIRURGIE. 2019; 33(1): 25-39.
• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C, Lavie CJ, Konstantinides S, Lankeit M. Survival Benefit of Obese Patients With Pulmonary Embolism. Mayo Clin Proc 2019;94(10):1960-1973.
• Keller K, Tesche C, Gerhold-Ay A, Nickels S, Klok FA, Rappold L, Hasenfuss G, Dellas C, Konstantinides SV, Lankeit M. Quality of life and functional limitations after pulmonary embolism and its prognostic relevance. J Thromb Haemost 2019;17(11):1923-1934.
• Klingenberg R, Schlager O, Limacher A, Mean M, Vuilleumier N, Beer JH, Staub D, Frauchiger B, Aschwanden M, Lämmle B, Righini M, Egloff M, Osterwalder J, Angelillo-Scherrer A, Kucher N, Banyai M, Rodondi N, von Eckardstein A, Aujesky D, Husmann M, Matter CM. Risk stratification of elderly patients with acute pulmonary embolism. Eur J Clin Invest 2019;49(9):e13154.
• Haub J, Roehrig N, Uhrin P, Schabbauer G, Eulberg D, Melchior F, Shahneh F, Probst HC, Becker C, Steinbrink K, Raker VK. Intervention of Inflammatory Monocyte Activity Limits Dermal Fibrosis. J Invest Dermatol 2019;139(10):2144-2153.
• Finger S, Knorr M, Molitor M, Schüler R, Garlapati V, Waisman A, Brandt M, Münzel T, Bopp T, Kossmann S, Karbach S, Wenzel P. A sequential interferon gamma directed chemotactic cellular immune response determines survival and cardiac function post-myocardial infarction. Cardiovasc Res 2019;115(13):1907-1917.
• Ten Cate V, Nagler M, Panova-Noeva M, Eggebrecht L, Arnold N, Lamparter H, Hermanns MI, Ten Cate H, Prins MH, Espinola-Klein C, Münzel T, Lackner KJ, Wild PS, Prochaska JH. The diagnostic performance of renal function-adjusted D-dimer testing in individuals suspected of having venous thromboembolism. Haematologica 2019;104(9):e424-e427.
• Trenkwalder T, Rübsamen N, Schmitt VH, Arnold N, Kaess BM, Sinning CR, Zeller T, Beutel ME, Schmidtmann I, Nickels S, Pfeiffer N, Leuschner A, Münzel T, Lackner KJ, Hengstenberg C, Blankenberg S, Wild PS, Reinhard W, Schnabel R. Left ventricular geometry and function in early repolarization: results from the population-based Gutenberg Health Study. Clin Res Cardiol 2019;108(10):1107-1116.
• van Dorland HA, Taleghani MM, Sakai K, Friedman KD, George JN, Hrachovinova I, Knobl PN, von Krogh AS, Schneppenheim R, Aebi-Huber I, Butikofer L, Largiader CR, Cermakova Z, Kokame K, Miyata T, Yagi H, Terrell DR, Vesely SK, Matsumoto M, Lämmle B, Fujimura Y, Kremer Hovinga JA, Hereditary TTP Registry. The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017. Haematologica 2019;104(10):2107-2115.
• Schmidtmann I, Konstantinides S, Binder H. Power of the Wilcoxon-Mann-Whitney test for non-inferiority in the presence of death-censored observations. Biom J 2019;61(5):1187-1200.
• Keller K, Hobohm L, Geyer M, Münzel T, Lavie CJ, Ostad MA, Espinola-Klein C. Obesity paradox in peripheral artery disease. Clin Nutr 2019;38(5):2269-2276.
• Keller K, Hobohm L, Münzel T, Ostad MA. Sex-specific differences regarding seasonal variations of incidence and mortality in patients with myocardial infarction in Germany. Int J Cardiol 2019;287:132-138.
• Ernst M, Brähler E, Klein EM, Jünger C, Wild PS, Faber J, Schneider A, Beutel ME. Parenting in the face of serious illness: Childhood cancer survivors remember different rearing behavior than the general population. Psychooncology 2019;28(8):1663-1670.
• von Jeinsen B, Liebetrau C, Palapies L, Tzikas S, Zeller T, Bickel C, Schmidt A, Tubaro M, Lackner KJ, Sar F, Baldus S, Zeiher AM, Blankenberg S, Gori T, Münzel T, Hamm CW, Wild PS, Keller T. Identification of acute myocardial infarction in elderly patients using optimized highly sensitive troponin I thresholds. Biomarkers 2019;24(6):549-555.
• Althaus K, Zieger B, Bakchoul T, Jurk K. Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment. Thromb Haemost 2019;119(7):1154-1161.
• Duhme C, Lehwald N, Kehrel BE, Bauchrowitz E, Ngepi A, Schmelzle M, Kolokotronis T, Benhidjeb T, Krüger M, Jurk K, Knoefel WT, Robson SC, Schulte Am Esch J. CD133(+) bone marrow stem cells (BMSC) control platelet activation - Role of ectoNTPDase-1 (CD39). Blood Cells Mol Dis 2019;77:142-148.
• Hollerbach A, Müller-Calleja N, Ritter S, Häuser F, Canisius A, Orning C, Jurk K, Lackner KJ. Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors. Thromb Haemost 2019;119(7):1147-1153.
• Trabold K, Makhoul S, Gambaryan S, van Ryn J, Walter U, Jurk K. The Direct Thrombin Inhibitors Dabigatran and Lepirudin Inhibit GPIbalpha-Mediated Platelet Aggregation. Thromb Haemost 2019;119(6):916-929.
• Ponto KA, Scharrer I, Binder H, Korb C, Rosner AK, Ehlers TO, Rieser N, Grübel NC, Rossmann H, Wild PS, Feltgen N, Pfeiffer N, Mirshahi A. Hypertension and multiple cardiovascular risk factors increase the risk for retinal vein occlusions: results from the Gutenberg Retinal Vein Occlusion Study. J Hypertens 2019;37(7):1372-1383.
• Verma D, Kumar R, Pereira RS, Karantanou C, Zanetti C, Minciacchi VR, Fulzele K, Kunz K, Hoelper S, Zia-Chahabi S, Jabagi MJ, Emmerich J, Dray-Spira R, Kuhlee F, Hackmann K, Schroeck E, Wenzel P, Müller S, Filmann N, Fontenay M, Pajevic PD, Krause DS. Vitamin K antagonism impairs the bone marrow microenvironment and hematopoiesis. Blood 2019;134(3):227-238.
• Hobohm L, von Bardeleben RS, Ostad MA, Wenzel P, Münzel T, Gori T, Keller K. 5-Year Experience of In-Hospital Outcomes After Percutaneous Left Atrial Appendage Closure in Germany. JACC Cardiovasc Interv 2019;12(11):1044-1052.
• Schüler R, Efentakis P, Wild J, Lagrange J, Garlapati V, Molitor M, Kossmann S, Oelze M, Stamm P, Li H, Schäfer K, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH. T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of (.)NO/cGMP Signaling. Oxid Med Cell Longev 2019;2019:6721531.
• Koizume S, Takahashi T, Yoshihara M, Nakamura Y, Ruf W, Takenaka K, Miyagi E, Miyagi Y. Cholesterol Starvation and Hypoxia Activate the FVII Gene via the SREBP1-GILZ Pathway in Ovarian Cancer Cells to Produce Procoagulant Microvesicles. Thromb Haemost 2019;119(7):1058-1071. 
• Ten Cate V, Koeck T, Panova-Noeva M, Rapp S, Prochaska JH, Lenz M, Schulz A, Eggebrecht L, Hermanns MI, Heitmeier S, Krahn T, Laux V, Münzel T, Leineweber K, Konstantinides SV, Wild PS, Collaborators: Investigators FBS, Study VT. A prospective cohort study to identify and evaluate endotypes of venous thromboembolism: Rationale and design of the Genotyping and Molecular Phenotyping in Venous ThromboEmbolism project (GMP-VTE). Thromb Res 2019;181:84-91.
• Valerio L, Ambaglio C, Barone M, Ciola M, Konstantinides SV, Mahmoudpour SH, Picchi C, Pieresca C, Trinchero A, Barco S. Recurrence Risk after First Symptomatic Distal versus Proximal Deep Vein Thrombosis According to Baseline Risk Factors. TH Open 2019;3(1):e58-e63. 
• Kölmel S, Hobohm L, Käberich A, Krieg VJ, Bochenek ML, Wenzel P, Wiedenroth CB, Liebetrau C, Hasenfuss G, Mayer E, Konstantinides SV, Schäfer K, Guth S, Lankeit M. Potential Involvement of Osteopontin in Inflammatory and Fibrotic Processes in Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension. Thromb Haemost 2019;119(8):1332-1346.
• Prochaska JH, Hausner C, Nagler M, Göbel S, Eggebrecht L, Panova-Noeva M, Arnold N, Lauterbach M, Bickel C, Michal M, Hardt R, Espinola-Klein C, Lackner KJ, Münzel T, Wild PS. Subtherapeutic Anticoagulation Control under Treatment with Vitamin K-Antagonists-Data from a Specialized Coagulation Service. Thromb Haemost 2019;119(8):1347-1357.
• Fiess A, Schuster AK, Nickels S, Urschitz MS, Elflein HM, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N. Association of Low Birth Weight With Altered Corneal Geometry and Axial Length in Adulthood in the German Gutenberg Health Study. JAMA Ophthalmol 2019;137(5):507-514.
• Kresoja KP, Ebner M, Rogge NIJ, Sentler C, Keller K, Hobohm L, Hasenfuss G, Konstantinides SV, Pieske B, Lankeit M. Prediction and prognostic importance of in-hospital major bleeding in a real-world cohort of patients with pulmonary embolism. Int J Cardiol 2019;290:144-149.
• Barco S, Russo M, Vicaut E, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Danays T, Dellas C, Duerschmied D, Empen K, Ferrari E, Galie N, Jimenez D, Klok FA, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N, Palazzini M, Pruszczyk P, Rugolotto M, Salvi A, Sanchez O, Schellong S, Sobkowicz B, Meyer G, Konstantinides SV. Incomplete echocardiographic recovery at 6 months predicts long-term sequelae after intermediate-risk pulmonary embolism. A post-hoc analysis of the Pulmonary Embolism Thrombolysis (PEITHO) trial. Clin Res Cardiol 2019;108(7):772-778.
• Eggebrecht L, Prochaska JH, Tröbs SO, Schwuchow-Thonke S, Göbel S, Diestelmeier S, Schulz A, Arnold N, Panova-Noeva M, Koeck T, Rapp S, Gori T, Lackner KJ, Ten Cate H, Münzel T, Wild PS. Direct oral anticoagulants and vitamin K antagonists are linked to differential profiles of cardiac function and lipid metabolism. Clin Res Cardiol 2019;108(7):787-796.
• Drosos I, Pavlaki M, Ortega Carrillo MDP, Kourkouli A, Buschmann K, Konstantinou F, Gogiraju R, Bochenek ML, Chalikias G, Tortopidis C, Vahl CF, Mikroulis D, Tziakas D, Münzel T, Konstantinides S, Schäfer K. Increased Lymphangiogenesis and Lymphangiogenic Growth Factor Expression in Perivascular Adipose Tissue of Patients with Coronary Artery Disease. J Clin Med 2019;8(7).
• Akhtar J, More P, Albrecht S, Marini F, Kaiser W, Kulkarni A, Wojnowski L, Fontaine JF, Andrade-Navarro MA, Silies M, Berger C. TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay. Life Sci Alliance 2019;2(4).
• Marini F, Binder H. pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components. BMC Bioinformatics 2019;20(1):331.
• Klok FA, Presles E, Tromeur C, Barco S, Konstantinides SV, Sanchez O, Pernod G, Raj L, Robin P, Le Roux PY, Hoffman C, Melac S, Bertoletti L, Girard P, Laporte S, Mismetti P, Meyer G, Leroyer C, Couturaud F, Investigators P-P. Evaluation of the predictive value of the bleeding prediction score VTE-BLEED for recurrent venous thromboembolism. Res Pract Thromb Haemost 2019;3(3):364-371.
• Keller K, Rappold L, Gerhold-Ay A, Hobohm L, Hasenfuss G, Konstantinides SV, Dellas C, Lankeit M. Sex-specific differences in pulmonary embolism. Thromb Res 2019;178:173-181.
• Koriath M, Müller C, Pfeiffer N, Nickels S, Beutel M, Schmidtmann I, Rapp S, Münzel T, Westermann D, Karakas M, Wild PS, Lackner KJ, Blankenberg S, Zeller T. Relative Telomere Length and Cardiovascular Risk Factors. Biomolecules 2019;9(5).
• Ernst M, Tibubos AN, Unterrainer J, Burghardt J, Brähler E, Wild PS, Jünger C, Faber J, Schneider A, Beutel ME. Status and predictors of planning ability in adult long-term survivors of CNS tumors and other types of childhood cancer. Sci Rep 2019;9(1):7290.
• Mahmoudpour SH, Jankowski M, Valerio L, Becker C, Espinola-Klein C, Konstantinides S, Quitzau K, Barco S. Safety of low-dose subcutaneous recombinant interleukin-2: systematic review and meta-analysis of randomized controlled trials. Sci Rep 2019;9(1):7145.
• Keller K, Hobohm L, Engelhardt M. Risk of venous thromboembolism after endoprosthetic surgeries: lower versus upper extremity endoprosthetic surgeries. Heart Vessels 2019;34(5):815-823.
• Unterrainer JM, Rahm B, Kaller CP, Wild PS, Münzel T, Blettner M, Lackner K, Pfeiffer N, Beutel ME. Assessing Planning Ability Across the Adult Life Span in a Large Population-Representative Sample: Reliability Estimates and Normative Data for the Tower of London (TOL-F) Task. J Int Neuropsychol Soc 2019;25(5):520-529.
• van Geffen JP, Brouns SLN, Batista J, McKinney H, Kempster C, Nagy M, Sivapalaratnam S, Baaten C, Bourry N, Frontini M, Jurk K, Krause M, Pillitteri D, Swieringa F, Verdoold R, Cavill R, Kuijpers MJE, Ouwehand WH, Downes K, Heemskerk JWM. High-throughput elucidation of thrombus formation reveals sources of platelet function variability. Haematologica 2019;104(6):1256-1267.
• Jäger M, Hubert A, Gogiraju R, Bochenek ML, Münzel T, Schäfer K. Inducible Knockdown of Endothelial Protein Tyrosine Phosphatase-1B Promotes Neointima Formation in Obese Mice by Enhancing Endothelial Senescence. Antioxid Redox Signal 2019;30(7):927-944.
• Keller K, Hobohm L, Münzel T, Ostad MA. Syncope in the German Nationwide inpatient sample - Syncope in atrial fibrillation/flutter is related to pulmonary embolism and is accompanied by higher in-hospital mortality. Eur J Intern Med 2019;62:29-36.
• Burghardt J, Klein E, Brähler E, Ernst M, Schneider A, Eckerle S, Neu MA, Wingerter A, Henninger N, Panova‐Noeva M, Prochaska J, Wild P, Beutel M, Faber J. Prevalence of mental distress among adult survivors of childhood cancer in Germany—Compared to the general population. Cancer Medicine 2019;8(4):1865-1874.
• Hansen M, Peltier J, Killy B, Amin B, Bodendorfer B, Hartlova A, Uebel S, Bosmann M, Hofmann J, Buttner C, Ekici AB, Kuttke M, Franzyk H, Foged C, Beer-Hammer S, Schabbauer G, Trost M, Lang R. Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling. Mol Cell Proteomics 2019;18(4):669-685.
• Rothmeier AS, Versteeg HH, Ruf W. Factor VIIa-induced interaction with integrin controls the release of tissue factor on extracellular vesicles from endothelial cells. J Thromb Haemost 2019;17(4):627-634.
• Tziakas DN, Chalikias G, Pavlaki M, Kareli D, Gogiraju R, Hubert A, Bohm E, Stamoulis P, Drosos I, Kikas P, Mikroulis D, Giatromanolaki A, Georgiadis GS, Konstantinou F, Argyriou C, Münzel T, Konstantinides SV, Schäfer K. Lysed Erythrocyte Membranes Promote Vascular Calcification. Circulation 2019;139(17):2032-2048.
• von Bardeleben RS, Hobohm L, Kreidel F, Ostad MA, Schulz E, Konstantinides S, Lankeit M, Feldman T, Münzel T, Keller K. Incidence and in-hospital safety outcomes of patients undergoing percutaneous mitral valve edge-to-edge repair using MitraClip: five-year German national patient sample including 13,575 implants. EuroIntervention 2019;14(17):1725-1732.
• Barco S, Granziera S, Coppens M, Douxfils J, Nijkeuter M, Riva N, Vanassche T, Zhang G, Lin M, Kamphuisen PW, Cohen AT, Beyer-Westendorf J. Determinants of the Quality of Warfarin Control after Venous Thromboembolism and Validation of the SAMe-TT2-R2 Score: An Analysis of Hokusai-VTE. Thromb Haemost 2019;119(4):675-684.
• Keller K, Geyer M, Münzel T, Ostad MA, Gori T. Impact of atrial fibrillation on in-hospital mortality of ischemic stroke patients and identification of promoting factors of atrial thrombi - Results from the German nationwide inpatient sample and a single-center retrospective cohort. Medicine (Baltimore) 2019;98(4):e14086.
• Keller K, Hobohm L, Münzel T, Ostad MA. Impact of symptomatic atherosclerosis in patients with pulmonary embolism. Int J Cardiol 2019;278:225-231.
• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C. Impact of chronic obstructive pulmonary disease on the outcomes of patients with peripheral artery disease. Respir Med 2019;147:1-6.
• Beutel ME, Wiltink J, Ghaemi Kerahrodi J, Tibubos AN, Brähler E, Schulz A, Wild P, Münzel T, Lackner K, König J, Pfeiffer N, Michal M, Henning M. Somatic symptom load in men and women from middle to high age in the Gutenberg Health Study - association with psychosocial and somatic factors. Sci Rep 2019;9(1):4610.
• Dörr M, Hamburg NM, Müller C, Smith NL, Gustafsson S, Lehtimäki T, Teumer A, Zeller T, Li X, Lind L, Raitakari OT, Völker U, Blankenberg S, McKnight B, Morris AP, Kähönen M, Lemaitre RN, Wild PS, Nauck M, Völzke H, Münzel T, Mitchell GF, Psaty BM, Lindgren CM, Larson MG, Felix SB, Ingelsson E, Lyytikäinen LP, Herrington D, Benjamin EJ, Schnabel RB. Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. Circ Genom Precis Med 2019;12(2):e002409.
• Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonovic N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotic A, Jonjic S, Müller M, Strobl B. Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1. Cell Rep 2019;26(9):2394-2406 e2395.
• Sharma A, Steven S, Bosmann M. The pituitary gland prevents shock-associated death by controlling multiple inflammatory mediators. Biochem Biophys Res Commun 2019;509(1):188-193.
• Hewel C, Kaiser J, Wierczeiko A, Linke J, Reinhardt C, Endres K, Gerber S. Common miRNA Patterns of Alzheimer's Disease and Parkinson's Disease and Their Putative Impact on Commensal Gut Microbiota. Front Neurosci 2019;13:113.
• Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF. Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Nat Commun 2019;10(1):1198.
• Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG. Virus envelope tissue factor promotes infection in mice. J Thromb Haemost 2019;17(3):482-491.
• Chalikias G, Serif L, Kikas P, Thomaidis A, Stakos D, Makrygiannis D, Chatzikyriakou S, Papoulidis N, Voudris V, Lantzouraki A, Müller M, Arampatzis S, Konstantinides S, Tziakas D. Long-term impact of acute kidney injury on prognosis in patients with acute myocardial infarction. Int J Cardiol 2019;283:48-54.
• Gogiraju R, Hubert A, Fahrer J, Straub BK, Brandt M, Wenzel P, Münzel T, Konstantinides S, Hasenfuss G, Schäfer K. Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling. Circ Heart Fail 2019;12(1):e005622.
• Kostrubiec M, Plywaczewska M, Jimenez D, Lankeit M, Ciurzynski M, Konstantinides S, Pruszczyk P. The Prognostic Value of Renal Function in Acute Pulmonary Embolism-A Multi-Centre Cohort Study. Thromb Haemost 2019;119(1):140-148.
• Kiouptsi K, Finger S, Garlapati VS, Knorr M, Brandt M, Walter U, Wenzel P, Reinhardt C. Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice. Biol Open 2019;8(1).
• Barco S, Mahmoudpour SH, Planquette B, Sanchez O, Konstantinides SV, Meyer G. Prognostic value of right ventricular dysfunction or elevated cardiac biomarkers in patients with low-risk pulmonary embolism: a systematic review and meta-analysis. Eur Heart J 2019;40(11):902-910.
• Kröller-Schön S, Jansen T, Tran TLP, Kvandova M, Kalinovic S, Oelze M, Keaney JF, Jr., Foretz M, Viollet B, Daiber A, Kossmann S, Lagrange J, Frenis K, Wenzel P, Münzel T, Schulz E. Endothelial alpha1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction. Basic Res Cardiol 2019;114(2):8.
• Schüler R, Brand A, Klebow S, Wild J, Veras FP, Ullmann E, Roohani S, Kolbinger F, Kossmann S, Wohn C, Daiber A, Münzel T, Wenzel P, Waisman A, Clausen BE, Karbach S. Antagonization of IL-17A Attenuates Skin Inflammation and Vascular Dysfunction in Mouse Models of Psoriasis. J Invest Dermatol 2019;139(3):638-647.
• Barco S, Klok FA, Mahe I, Marchena PJ, Ballaz A, Rubio CM, Adarraga MD, Mastroiacovo D, Konstantinides SV, Monreal M, Investigators R. Impact of sex, age, and risk factors for venous thromboembolism on the initial presentation of first isolated symptomatic acute deep vein thrombosis. Thromb Res 2019;173:166-171.
• Klok FA, Pruefer D, Rolf A, Konstantinides SV. Magnetic resonance direct thrombus imaging for pre-operative assessment of acute thrombosis in chronic thromboembolic pulmonary hypertension. Eur Heart J 2019;40(11):944.
• Sacco C, Zane F, Granziera S, Holm K, Creemers-Schild D, Hotz MA, Turpini E, Valentini A, Righini C, Karkos PD, Verhamme P, Di Nisio M, Konstantinides S, Pecci A, Barco S, Lemierre Study G. Lemierre Syndrome: Clinical Update and Protocol for a Systematic Review and Individual Patient Data Meta-analysis. Hamostaseologie 2019;39(1):76-86.
• Prochaska JH, Luther N, Brähler M, Schulz A, Hermanns MI, Lackner KJ, Espinola-Klein C, Münzel T, Wild PS, Becker C. Acute deep vein thrombosis suppresses peripheral T cell effector function. Br J Haematol 2019;184(5):847-850.
• Hain T, Melchior F, Kamenjarin N, Muth S, Weslati H, Clausen BE, Mahnke K, Silva-Vilches C, Schutze K, Sohl J, Radsak MP, Bundgen G, Bopp T, Danckwardt S, Schild H, Probst HC. Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses. J Invest Dermatol 2019;139(2):422-429.
• Bibli SI, Papapetropoulos A, Iliodromitis EK, Daiber A, Randriamboavonjy V, Steven S, Brouckaert P, Chatzianastasiou A, Kypreos KE, Hausenloy DJ, Fleming I, Andreadou I. Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug. Cardiovasc Res 2019;115(3):625-636.
• Börschel CS, Rübsamen N, Ojeda FM, Wild PS, Hoffmann BA, Prochaska JH, Gori T, Lackner KJ, Blankenberg S, Zeller T, Münzel T, Schnabel RB. Noninvasive peripheral vascular function and atrial fibrillation in the general population. J Hypertens 2019;37(5):928-934.
• Panova-Noeva M, Neu MA, Eckerle S, Spix C, Schneider A, Schmidtmann I, Spronk HM, Pfeiffer N, Beutel M, Lackner KJ, Münzel T, Ten Cate H, Merzenich H, Faber J, Wild PS. Cardiovascular risk factors are important determinants of platelet-dependent thrombin generation in adult survivors of childhood cancer. Clin Res Cardiol 2019;108(4):438-447.
• Eggebrecht L, Nagler M, Göbel S, Lamparter H, Keller K, Wagner B, Panova-Noeva M, Ten Cate V, Bickel C, Lauterbach M, Espinola-Klein C, Hardt R, Münzel T, Prochaska JH, Wild PS. Relevance of Polypharmacy for Clinical Outcome in Patients Receiving Vitamin K Antagonists. J Am Geriatr Soc 2019;67(3):463-470.
• Keller K. Life Expectancy of Olympic Wrestling Champions in Comparison to the General Population. J Community Health 2019;44(1):61-67.

Reviews 2019

• Lässiger-Herfurth A, Pontarollo G, Grill A, Reinhardt C. The Gut Microbiota in Cardiovascular Disease and Arterial Thrombosis. Microorganisms 2019;7(12). 
• Panova-Noeva M, van der Meijden PEJ, Ten Cate H. Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of Platelets. J Clin Med 2019;9(1).
• Barco S. What's the Matter with Distal Deep Vein Thrombosis? Thromb Haemost 2019;19(10):1547-1549.
• Klok FA, Barco S. Optimal management of hormonal contraceptives after an episode of venous thromboembolism. Thromb Res 2019;181 Suppl 1:S1-S5.
• Lämmle B. Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy: Pathophysiology and Differentiation from Graft versus Host Disease. Thromb Haemost 2019;119(9):1382. 
• Bayer F, Ascher S, Pontarollo G, Reinhardt C. Antibiotic Treatment Protocols and Germ-Free Mouse Models in Vascular Research. Front Immunol 2019;10:2174.
• Keller K, Lankeit M. Current treatment of acute pulmonary embolism. PNEUMOLOGE. 2019; 16(5): 279-288. 
• Hobohm L, Lankeit M. [Pulmonary Embolism]. Dtsch Med Wochenschr 2019;144(18):1286-1300.
• Konstantinides SV, Meyer G. The 2019 ESC Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism. Eur Heart J 2019;40(42):3453-3455.
• Daiber A, Kröller-Schön S, Frenis K, Oelze M, Kalinovic S, Vujacic-Mirski K, Kuntic M, Bayo Jimenez MT, Helmstädter J, Steven S, Korac B, Münzel T. Environmental noise induces the release of stress hormones and inflammatory signaling molecules leading to oxidative stress and vascular dysfunction-Signatures of the internal exposome. Biofactors 2019;45(4):495-506.
• Lackner KJ, Müller-Calleja N. Pathogenesis of antiphospholipid syndrome: recent insights and emerging concepts. Expert Rev Clin Immunol 2019;15(2):199-209.
• Daiber A, Xia N, Steven S, Oelze M, Hanf A, Kröller-Schön S, Münzel T, Li H. New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease. Int J Mol Sci 2019;20(1).
• Steven S, Frenis K, Oelze M, Kalinovic S, Kuntic M, Bayo Jimenez MT, Vujacic-Mirski K, Helmstadter J, Kröller-Schön S, Münzel T, Daiber A. Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease. Oxid Med Cell Longev 2019;2019:7092151.
• Lackner KJ, Müller-Calleja N. Cofactor-Independent Antiphospholipid Antibodies: Implications for Pathogenesis, Diagnosis, and Treatment of Antiphospholipid Syndrome. Hamostaseologie 2019;39(2):188-194.
• Karbach S, Lagrange J, Wenzel P. Thromboinflammation and Vascular Dysfunction. Hamostaseologie 2019;39(2):180-187.
• Reinhardt C. The Gut Microbiota as an Influencing Factor of Arterial Thrombosis. Hamostaseologie 2019;39(2):173-179.
• Madhusudhan T, Ruf W. Coagulation Signalling and Metabolic Disorders: Lessons Learned from Animal Models. Hamostaseologie 2019;39(2):164-172.
• Panova-Noeva M, Eggebrecht L, Prochaska JH, Wild PS. Potential of Multidimensional, Large-scale Biodatabases to Elucidate Coagulation and Platelet Pathways as an Approach towards Precision Medicine in Thrombotic Disease. Hamostaseologie 2019;39(2):152-163.
• Jurk K, Walter U. New Insights into Platelet Signalling Pathways by Functional and Proteomic Approaches. Hamostaseologie 2019;39(2):140-151. 
• Bochenek ML, Schäfer K. Role of Endothelial Cells in Acute and Chronic Thrombosis. Hamostaseologie 2019;39(2):128-139.
• Barco S, Konstantinides SV. Optimizing the Personalized, Risk-Adjusted Management of Pulmonary Embolism: An Integrated Clinical Trial Programme. Hamostaseologie 2019;39(2):117-127. 
• Johannes Wild, Philip Wenzel. „Myocardial injury“ und Myokardinfarkt – Konsequenzen für die Klinik im Kontext aktueller Leitlinien. Aktuel Kardiol 2019; 8(03): 193-198.
• Klok FA, Barco S, Siegerink B. Measuring functional limitations after venous thromboembolism: A call to action. Thromb Res 2019;178:59-62.
• Wenzel P. Monocytes as immune targets in arterial hypertension. Br J Pharmacol 2019;176(12):1966-1977.
• Keller K, Hobohm L, Münzel T, Ostad MA. Incidence of infective endocarditis before and after the guideline modification regarding a more restrictive use of prophylactic antibiotics therapy in the USA and Europe. Minerva Cardioangiol 2019;67(3):200-206.
• Formes H, Reinhardt C. The gut microbiota - a modulator of endothelial cell function and a contributing environmental factor to arterial thrombosis. Expert Rev Hematol 2019:1-9.
• Keller K. Sarcopenia. Wien Med Wochenschr 2019;169(7-8):157-172.
• Gogiraju R, Bochenek ML, Schäfer K. Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure. Front Cardiovasc Med 2019;6:20.
• Petris AO, Konstantinides S, Tint D, Cimpoesu D, Pop C. Therapeutic Advances in Emergency Cardiology: Acute Pulmonary Embolism. Am J Ther 2019;26(2):e248-e256.
• Aissaoui N, Konstantinides S, Meyer G. What's new in severe pulmonary embolism? Intensive Care Med 2019;45(1):75-77.

Editorials und Fachbeiträge 2019

• Valerio L, Trinchero A, Barco S. Telemedicine and decentralized models of care: from anticoagulant monitoring to an expanded concept of vascular medicine. Intern Emerg Med 2019;14(8):1213-1215.
• Bauersachs R, Langer F, Kalka C, Konstantinides S, Klamroth R, Oldenburg J, Schellong S, Scholz U, Stucker M, Lindhoff-Last E. Treatment of the antiphospholipid syndrome with direct oral anticoagulantsPosition statement of German societies. Vasa 2019;48(6):483-486.
• Barco S, Konstantinides SV, Lankeit M. Response to 'Detecting right ventricular dysfunction in patients diagnosed with low-risk pulmonary embolism: is routine computed tomographic pulmonary angiography sufficient?'. Eur Heart J 2019;40(40):3357-3358.
• Linde C, Members of the ESC Membership Committee the ESC Officers Sophie Squarta, Director Membership Community. The Membership Committee of the ESC. Cardiovasc Res 2019;115(12):e130-e132.
• Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ainle FN, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, The Task Force for the diagnosis management of acute pulmonary embolism of the European Society of Cardiology. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J 2019;54(3).
• Rosenkranz S, Diller GP, Dumitrescu D, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Kaemmerer H, Klose H, Kovacs G, Konstantinides S, Lang IM, Lange TJ, Leuchte H, Mayer E, Olschewski A, Olschewski H, Olsson KM, Opitz C, Schermuly RT, Seeger W, Wilkens H, Hoeper MM. [Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension]. Dtsch Med Wochenschr 2019;144(19):1367-1372.
• Reinhardt C. The Microbiota: A Microbial Ecosystem Built on Mutualism Prevails. J Innate Immun 2019;11(5):391-392.
• Ruf W. Translational Research in Thrombosis and Haemostasis. Hamostaseologie 2019;39(2):115-116.
• Konstantinides SV, Münzel T, Ruf W. Center for Thrombosis and Hemostasis Mainz. Eur Heart J 2019;40(23):1827-1829.
• Keller K, Hobohm L. Identification of normotensive patients with pulmonary embolism who may benefit from thrombolysis. Int J Cardiol 2019;281:125-126.
• Prochaska JH, Tröbs SO, Wild PS. PCSK9: A link between air pollution and cardiovascular disease? Eur J Prev Cardiol 2019;26(6):576-577.
• Pontarollo G, Melzow F, Reinhardt C. Comment on "Endothelial Protein C Receptor (EPCR), Protease Activated Receptor-1 (PAR-1) and Their Interplay in Cancer Growth and Metastatic Dissemination" Cancers 2019, 11, 51. Cancers (Basel) 2019;11(3).
• Becker C, Reinhardt C. Unexpected role of natural killer cell-derived interferon-gamma as a driver of NETosis and DVT. J Thromb Haemost 2019;17(2):400-402.
• Ozkan J. 2019. Stavros V. Konstantinides MD. Eur Heart J 40:1826-1827.

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Originalartikel 2018

• Mahmoudpour SH, Asselbergs FW, Souverein PC, de Boer A, Maitland-van der Zee AH. Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study. Br J Clin Pharmacol 2018;84(10):2365-2372.
• Mahmoudpour SH, Bandapalli OR, da Silva Filho MI, Campo C, Hemminki K, Goldschmidt H, Merz M, Försti A. Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients. BMC Cancer 2018;18(1):820.
• Keller K, Beule J, Balzer JO, Dippold W. D-Dimer and thrombus burden in acute pulmonary embolism. Am J Emerg Med 2018;36(9):1613-1618.
• Steven S, Oelze M, Hausding M, Roohani S, Kashani F, Kröller-Schön S, Helmstädter J, Jansen T, Baum C, Iglarz M, Schulz E, Münzel T, Daiber A. The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation. Oxid Med Cell Longev 2018;2018:7845629.
• Barco S, Ende-Verhaar YM, Becattini C, Jimenez D, Lankeit M, Huisman MV, Konstantinides SV, Klok FA. Differential impact of syncope on the prognosis of patients with acute pulmonary embolism: a systematic review and meta-analysis. Eur Heart J 2018.
• Wilkens H, Konstantinides S, Lang IM, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohe C, Guth S, Held M, Hinrichs JB, Hoeper MM, Klepetko W, Kramm T, Kruger U, Lankeit M, Meyer BC, Olsson KM, Schafers HJ, Schmidt M, Seyfarth HJ, Ulrich S, Wiedenroth CB, Mayer E. Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations from the Cologne Consensus Conference 2018. Int J Cardiol 2018;272S:69-78.
• Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger D, Marini F, Poetsch A, Binder H, Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ, Westermann F, Danckwardt S. Transcriptome 3'end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma. Nat Commun 2018;9(1):5331.
• Dentali F, Barco S, Pegoraro S, Di Minno MND, Mastroiacovo D, Pomero F, Lodigiani C, Bagna F, Sartori M, Barillari G, Mumoli N, Napolitano M, Passamonti SM, Benedetti R, Ageno W, Di Nisio M. Residual vein obstruction in patients diagnosed with acute isolated distal deep vein thrombosis associated with active cancer. J Thromb Thrombolysis 2018;46(3):404-408.
• Scheres LJJ, Lijfering WM, Middeldorp S, Cheung YW, Barco S, Cannegieter SC, Coppens M. Measurement of coagulation factors during rivaroxaban and apixaban treatment: Results from two crossover trials. Res Pract Thromb Haemost 2018;2(4):689-695.
• Keller K, Beule J, Balzer JO, Dippold W. Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of Pulmonary Embolism) Study Programme. Acta Medica (Hradec Kralove) 2018;61(3):93-97.
• Keller K, Hobohm L, Engelhardt M. Impact of Atrial Fibrillation on Postoperative Adverse Outcomes of Surgical Patients With Knee Endoprosthetic Surgery. J Arthroplasty 2018;33(11):3567-3573.
• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C. Syncope in haemodynamically stable and unstable patients with acute pulmonary embolism - Results of the German nationwide inpatient sample. Sci Rep 2018;8(1):15789.
• Klok FA, Barco S, Turpie AGG, Haas S, Kreutz R, Mantovani LG, Gebel M, Herpers M, Bugge JP, Kostantinides SV, Ageno W. Predictive value of venous thromboembolism (VTE)-BLEED to predict major bleeding and other adverse events in a practice-based cohort of patients with VTE: results of the XALIA study. Br J Haematol 2018;183(3):457-465.
• Ligthart S, Vaez A, Vosa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM […] Wild PS […] Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. Am J Hum Genet 2018;103(5):691-706.
• Eggebrecht L, Prochaska JH, Schulz A, Arnold N, Jünger C, Gobel S, Laubert-Reh D, Binder H, Beutel ME, Pfeiffer N, Blankenberg S, Lackner KJ, Spronk HM, Ten Cate H, Münzel T, Wild PS. Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study. J Am Heart Assoc 2018;7(17):e008650.
• Göbel S*, Prochaska JH*, Eggebrecht L, Schmitz R, Jünger C, Lamparter H, Nagler M, Keller K, Coldewey M, Tröbs SO, Diestelmeier S, Schwuchow-Thonke S, Bickel C, Lauterbach M, Lackner KJ, Cate HT, Münzel T, Hardt R, Wild PS. Management of Oral Anti-Coagulation in Patients with Heart Failure-Insights from the ThrombEVAL Study. Thromb Haemost 2018;118(11):1930-1939. * equal contribution
• Haase T, Müller C, Krause J, Rothemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild PS, Michal M, Marini F, Karakas M, Lackner KJ, Blankenberg S, Zeller T. Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking. Biomolecules 2018;8(3).
• Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Boger RH, Münzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB. Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study. Biomolecules 2018;8(3).
• Tibubos AN, Beutel ME, Schulz A, Klein EM, Brahler E, Michal M, Münzel T, Wild PS, Lackner K, Konig J, Pfeiffer N, Wiltink J. Is assessment of depression equivalent for migrants of different cultural backgrounds? Results from the German population-based Gutenberg Health Study (GHS). Depress Anxiety 2018;35(12):1178-1189.
• van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS, Gibson Q, Gudbjartsson DF […] Wild PS […] Stefansson K, Stricker BH, van der Harst P, van Duijn CM, Wilson JF, Gharib SA, de Bakker PIW, Isaacs A, Arking DE, Sotoodehnia N. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nat Commun 2018;9(1):2904.
• Höhn R, Nickels S, Schuster AK, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N. Prevalence of glaucoma in Germany: results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 2018;256(9):1695-1702.
• Magnussen C, Ojeda FM, Wild PS, Sorensen N, Rostock T, Hoffmann BA, Prochaska J, Lackner KJ, Beutel ME, Blettner M, Pfeiffer N, Rzayeva N, Sinning CR, Blankenberg S, Münzel T, Zeller T, Schnabel RB. Atrial Fibrillation Manifestations Risk Factors and Sex Differences in a Population-Based Cohort (From the Gutenberg Health Study). Am J Cardiol 2018;122(1):76-82.
• Prochaska JH, Göbel S, Nagler M, Knöpfler T, Eggebrecht L, Lamparter H, Panova-Noeva M, Keller K, Coldewey M, Bickel C, Lauterbach M, Hardt R, Espinola-Klein C, Ten Cate H, Rostock T, Münzel T, Wild PS. Sustained atrial fibrillation increases the risk of anticoagulation-related bleeding in heart failure. Clin Res Cardiol 2018.
• Nourse J, Braun J, Lackner K, Hüttelmaier S, Danckwardt S. Large-scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system. J Thromb Haemost 2018;16(11):2233-2245.
• Colucci G, Helsing K, Biasiutti FD, Raio L, Schmid P, Tsakiris DA, Eberle B, Surbek D, Lämmle B, Alberio L. Standardized Management Protocol in Severe Postpartum Hemorrhage: A Single-Center Study. Clin Appl Thromb Hemost 2018;24(6):884-893.
• Klatt C, Krüger I, Zey S, Krott KJ, Spelleken M, Gowert NS, Oberhuber A, Pfaff L, Luckstadt W, Jurk K, Schaller M, Al-Hasani H, Schrader J, Massberg S, Stark K, Schelzig H, Kelm M, Elvers M. Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis. J Clin Invest 2018;128(9):3906-3925.
• Urbahn MA, Kaup SC, Reusswig F, Kruger I, Spelleken M, Jurk K, Klier M, Lang PA, Elvers M. Phospholipase D1 regulation of TNF-alpha protects against responses to LPS. Sci Rep 2018;8(1):10006.
• Falter T, Herold S, Weyer-Elberich V, Scheiner C, Schmitt V, von Auer C, Messmer X, Wild P, Lackner KJ, Lämmle B, Scharrer I. Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab. Thromb Haemost 2018;118(10):1743-1751.
• Brandt M, Giokoglu E, Garlapati V, Bochenek ML, Molitor M, Hobohm L, Schönfelder T, Münzel T, Kossmann S, Karbach SH, Schäfer K, Wenzel P. Pulmonary Arterial Hypertension and Endothelial Dysfunction Is Linked to NADPH Oxidase-Derived Superoxide Formation in Venous Thrombosis and Pulmonary Embolism in Mice. Oxid Med Cell Longev 2018;2018:1860513.
  Jansen T, Kröller-Schön S, Schönfelder T, Foretz M, Viollet B, Daiber A, Oelze M, Brandt M, Steven S, Kvandova M, Kalinovic S, Lagrange J, Keaney JF, Jr., Münzel T, Wenzel P, Schulz E. alpha1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction. Cardiovasc Res 2018;114(14):1883-1893.
• Kröller-Schön S, Daiber A, Steven S, Oelze M, Frenis K, Kalinovic S, Heimann A, Schmidt FP, Pinto A, Kvandova M, Vujacic-Mirski K, Filippou K, Dudek M, Bosmann M, Klein M, Bopp T, Hahad O, Wild PS, Frauenknecht K, Methner A, Schmidt ER, Rapp S, Mollnau H, Münzel T. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation. Eur Heart J 2018;39(38):3528-3539.
• Sotiriou E, Heiner S, Jansen T, Brandt M, Schmidt KH, Kreitner KF, Emrich T, Schultheiss HP, Schulz E, Münzel T, Wenzel P. Therapeutic implications of a combined diagnostic workup including endomyocardial biopsy in an all-comer population of patients with heart failure: a retrospective analysis. ESC Heart Fail 2018;5(4):630-641.
• Lindskog Jonsson A, Caesar R, Akrami R, Reinhardt C, Fak Hallenius F, Boren J, Bäckhed F. Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe(-/-) Mice. Arterioscler Thromb Vasc Biol 2018;38(10):2318-2326.
• Klok FA, Barco S, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Delcroix M, Lang IM. Determinants of diagnostic delay in chronic thromboembolic pulmonary hypertension: results from the European CTEPH Registry. Eur Respir J 2018;52(6).
• Kaymaz C, Akbal OY, Hakgor A, Tokgoz HC, Karagoz A, Tanboga IH, Tanyeri S, Keskin B, Turkday S, Demir D, Dogan C, Bayram Z, Acar RD, Guvendi B, Ozdemir N, Tapson VF, Konstantinides S. A five-year, single-centre experience on ultrasound-assisted, catheter-directed thrombolysis in patients with pulmonary embolism at high risk and intermediate to high risk. EuroIntervention 2018;14(10):1136-1143.
• Spyropoulos AC, Ageno W, Albers GW, Elliott CG, Halperin JL, Hiatt WR, Maynard GA, Steg PG, Weitz JI, Suh E, Spiro TE, Barnathan ES, Raskob GE, Investigators M. Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness. N Engl J Med 2018;379(12):1118-1127.
• Trinchero A, Scheres LJJ, Prochaska JH, Ambaglio C, Wild PS, Middeldorp S, Konstantinides SV, Barco S. Sex-specific differences in the distal versus proximal presenting location of acute deep vein thrombosis. Thromb Res 2018;172:74-79.
• Dellas C, Lobo JL, Rivas A, Ballaz A, Portillo AK, Nieto R, Del Rey JM, Zamorano JL, Lankeit M*, Jimenez D*. Risk stratification of acute pulmonary embolism based on clinical parameters, H-FABP and multidetector CT. Int J Cardiol 2018;265:223-228. *equal contribution.
• Khandagale A, Kittner JM, Mann A, Ascher S, Kollar B, Reinhardt C. Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis. Biol Open 2018;7(7).
• Westmeier D, Solouk-Saran D, Vallet C, Siemer S, Docter D, Götz H, Männ L, Hasenberg A, Hahlbrock A, Erler K, Reinhardt C, Schilling O, Becker S, Gunzer M, Hasenberg M, Knauer SK, Stauber RH. Nanoparticle decoration impacts airborne fungal pathobiology. Proc Natl Acad Sci U S A 2018;115(27):7087-7092.
• Dellas C, Lobo JL, Rivas A, Ballaz A, Portillo AK, Nieto R, Del Rey JM, Zamorano JL, Lankeit M, Jimenez D. Risk stratification of acute pulmonary embolism based on clinical parameters, H-FABP and multidetector CT. Int J Cardiol 2018;265:223-228.
• Unterrainer JM, Domschke K, Rahm B, Wiltink J, Schulz A, Pfeiffer N, Lackner KJ, Münzel T, Wild PS, Beutel M. Subclinical levels of anxiety but not depression are associated with planning performance in a large population-based sample. Psychol Med 2018;48(1):168-174.
• Rezapour J, Nickels S, Schuster AK, Michal M, Münzel T, Wild PS, Schmidtmann I, Lackner K, Schulz A, Pfeiffer N, Beutel ME. Prevalence of depression and anxiety among participants with glaucoma in a population-based cohort study: The Gutenberg Health Study. BMC Ophthalmol 2018;18(1):157.
• Müller-Calleja N, Ritter S, Hollerbach A, Falter T, Lackner KJ, Ruf W. Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies. Blood Adv 2018;2(9):979-986.
• Rue-Albrecht K, Marini F, Soneson C, Lun ATL. iSEE: Interactive SummarizedExperiment Explorer. F1000Res 2018;7:741.
• Lamparter J, Schmidtmann I, Schuster AK, Siouli A, Wasielica-Poslednik J, Mirshahi A, Höhn R, Unterrainer J, Wild PS, Binder H, Lackner K, Beutel ME, Münzel T, Pfeiffer N, Hoffmann EM. Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness. PLoS One 2018;13(5):e0197682.
• Wiltink J, Michal M, Jünger C, Münzel T, Wild PS, Lackner KJ, Blettner M, Pfeiffer N, Brähler E, Beutel ME. Associations between degree and sub-dimensions of depression and metabolic syndrome (MetS) in the community: results from the Gutenberg Health Study (GHS). BMC Psychiatry 2018;18(1):114.
• Parry BA, Chang AM, Schellong SM, House SL, Fermann GJ, Deadmon EK, Giordano NJ, Chang Y, Cohen J, Robak N, Singer AJ, Mulrow M, Reibling ET, Francis S, Griffin SM, Prochaska JH, Davis B, McNelis P, Delgado J, Kumpers P, Werner N, Gentile NT, Zeserson E, Wild PS, Limkakeng AT, Jr., Walters EL, LoVecchio F, Theodoro D, Hollander JE, Kabrhel C. International, multicenter evaluation of a new D-dimer assay for the exclusion of venous thromboembolism using standard and age-adjusted cut-offs. Thromb Res 2018;166:63-70.
• Panova-Noeva M, Schulz A, Spronk HM, Beicht A, Laubert-Reh D, van Oerle R, Arnold N, Prochaska JH, Blettner M, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study. Thromb Haemost 2018;118(5):873-882.
• Yu Y, Boing AN, Hau CM, Hajji N, Ruf W, Sturk A, Nieuwland R. Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment. Thromb Haemost 2018;118(6):990-1000.
• Bochenek ML, Bauer T, Gogiraju R, Nadir Y, Mann A, Schönfelder T, Hunig L, Brenner B, Münzel T, Wenzel P, Konstantinides S, Schäfer K. The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice. Blood Adv 2018;2(11):1300-1314.
• Hellenkamp K, Pruszczyk P, Jimenez D, Wyzgal A, Barrios D, Ciurzynski M, Morillo R, Hobohm L, Keller K, Kurnicka K, Kostrubiec M, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study. Eur Respir J 2018;51(4).
• Faber J, Wingerter A, Neu MA, Henninger N, Eckerle S, Münzel T, Lackner KJ, Beutel ME, Blettner M, Rathmann W, Peters A, Meisinger C, Linkohr B, Neuhauser H, Kaatsch P, Spix C, Schneider A, Merzenich H, Panova-Noeva M, Prochaska JH, Wild PS. Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors: data from the German CVSS-study. Eur Heart J 2018;39(17):1555-1562.
• Herrmann WJ, Weikert C, Bergmann M, Boeing H, Katzke VA, Kaaks R, Tiller D, Greiser KH, Heier M, Meisinger C, Schmidt CO, Neuhauser H, Heidemann C, Jünger C, Wild PS, Schramm SH, Jöckel KH, Dörr M, Pischon T. [Assessing incident cardiovascular and metabolic diseases in epidemiological cohort studies in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2018;61(4):420-431.
• Lauber S, Limacher A, Tritschler T, Stalder O, Mean M, Righini M, Aschwanden M, Beer JH, Frauchiger B, Osterwalder J, Kucher N, Lämmle B, Cornuz J, Angelillo-Scherrer A, Matter CM, Husmann M, Banyai M, Staub D, Mazzolai L, Hugli O, Rodondi N, Aujesky D. Predictors and Outcomes of Recurrent Venous Thromboembolism in Elderly Patients. Am J Med 2018;131(6):703 e707-703 e716.
• Makhoul S, Walter E, Pagel O, Walter U, Sickmann A, Gambaryan S, Smolenski A, Zahedi RP, Jurk K. Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets. Nitric Oxide 2018;76:71-80.
• Ebert J, Wilgenbus P, Teiber JF, Jurk K, Schwierczek K, Döhrmann M, Xia N, Li H, Spiecker L, Ruf W, Horke S. Paraoxonase-2 regulates coagulation activation through endothelial tissue factor. Blood 2018;131(19):2161-2172.
• Panova-Noeva M, Schulz A, Arnold N, Hermanns MI, Prochaska JH, Laubert-Reh D, Spronk HM, Blettner M, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Coagulation and inflammation in long-term cancer survivors: results from the adult population. J Thromb Haemost 2018;16(4):699-708.
• Kurakula K, Koenis DS, Herzik MA, Jr., Liu Y, Craft JW, Jr., van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Sen M. Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica 2018;103(6):1073-1082.
• Eggebrecht L*, Prochaska JH*, Schleuter L, Nagler M, Hardt R, Schinzel H, Münzel T, Wild PS. [Physicians' Opinion on Health Care in Oral Anticoagulation]. Dtsch Med Wochenschr 2018;143(9):e76-e84.
• Siegismund CS, Escher F, Lassner D, Kühl U, Gross U, Fruhwald F, Wenzel P, Münzel T, Frey N, Linke RP, Schultheiss HP. Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis. Eur J Heart Fail 2018;20(4):751-757.
• Jimenez-Alcazar M, Limacher A, Panda R, Mean M, Bitterling J, Peine S, Renne T, Beer JH, Aujesky D, Lämmle B, Fuchs TA. Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism. PLoS One 2018;13(2):e0191150.
• Rothmeier AS, Liu E, Chakrabarty S, Disse J, Mueller BM, Ostergaard H, Ruf W. Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling. Blood 2018;131(6):674-685.
• Rodger M, Langlois N, Middeldorp S, Kahn S, Sandset PM, Brighton T, Huisman MV, Meyer G, Konstantinides S, Ageno W, Morange P, Garcia D, Kreuziger LB, Young L, Key N, Monreal M, Jimenez D. Initial strides for invent-VTE: Towards global collaboration to accelerate clinical research in venous thromboembolism. Thromb Res 2018;163:128-131.
• Schönfelder T, Brandt M, Kossmann S, Knopp T, Münzel T, Walter U, Karbach SH, Wenzel P. Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis. Sci Rep 2018;8(1):3013.
• Lagrange J, Kossmann S, Kiouptsi K, Wenzel P. Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls. J Vis Exp 2018(131).
• Barco S, Vicaut E, Klok FA, Lankeit M, Meyer G, Konstantinides SV, Investigators P. Improved identification of thrombolysis candidates amongst intermediate-risk pulmonary embolism patients: implications for future trials. Eur Respir J 2018;51(1).
• Oelze M, Welschof P, Knorr M, Tran LP, Ullmann E, Stamm P, Kröller-Schön S, Jansen T, Kopp M, Schulz E, Gori T, Burgin K, Scherhag A, Sartor D, Münzel T, Daiber A. Basic in vitro Characterization of the Vasodilatory Potential of 2-Aminoethyl Nitrate Fixed-Dose Combinations with Cilostazol, Metoprolol and Valsartan. Pharmacology 2018;101(1-2):54-63.
• Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kröller-Schön S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Münzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res 2018;114(2):312-323.
• Keller K, Münzel T, Ostad MA. Sex-specific differences in mortality and the obesity paradox of patients with myocardial infarction ages >70 y. Nutrition 2018;46:124-130.
• Wang X, Hausding M, Weng SY, Kim YO, Steven S, Klein T, Daiber A, Schuppan D. Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis. Antioxid Redox Signal 2018;28(2):87-109.

Reviews 2018

• Graf C, Ruf W. Tissue factor as a mediator of coagulation and signaling in cancer and chronic inflammation. Thromb Res 2018;164 Suppl 1:S143-S147
• Saffarzadeh M. Neutrophil Extracellular Traps as a Drug Target to Counteract Chronic and Acute Inflammation. Curr Pharm Biotechnol 2018;19(15):1196-1202.
• Reinhardt C. The Involvement of Toll-like Receptor-2 in Arterial Thrombus Formation. Hamostaseologie 2018;38(4):223-228.
• Carnevale D, Wenzel P. Mechanical stretch on endothelial cells interconnects innate and adaptive immune response in hypertension. Cardiovasc Res 2018;114(11):1432-1434.
• Kiouptsi K, Reinhardt C. Contribution of the commensal microbiota to atherosclerosis and arterial thrombosis. Br J Pharmacol 2018;175(24):4439-4449.
• Subramaniam S, Kanse SM, Kothari H, Reinhardt C, Fletcher C. Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood Coagul Fibrinolysis 2018;29(8):668-682.
• Westmeier D, Hahlbrock A, Reinhardt C, Fröhlich-Nowoisky J, Wessler S, Vallet C, Pöschl U, Knauer SK, Stauber RH. Nanomaterial-microbe cross-talk: physicochemical principles and (patho)biological consequences. Chem Soc Rev 2018;47(14):5312-5337.
• Barco S, Konstantinides SV. Pulmonary Embolism: Contemporary Medical Management and Future Perspectives. Ann Vasc Dis 2018;11(3):265-276.
• Nguyen TS, Lapidot T, Ruf W. Extravascular coagulation in hematopoietic stem and progenitor cell regulation. Blood 2018;132(2):123-131.
• Ruf W. ISTH 2017 Berlin revisited. Res Pract Thromb Haemost 2018;2(1):17-18.
• Zelaya H, Rothmeier AS, Ruf W. Tissue factor at the crossroad of coagulation and cell signaling. J Thromb Haemost 2018;16(10):1941-1952.
• Kiouptsi K, Ruf W, Reinhardt C. Microbiota-Derived Trimethylamine. Circ Res 2018;123(10):1112-1114.
• Prochaska JH, Wild PS. Traffic-associated air pollution as a risk factor for cancer in individuals with coronary artery disease. Eur J Prev Cardiol 2018:2047487318768942.
• Ruf W. Proteases, Protease-Activated Receptors, and Atherosclerosis. Arterioscler Thromb Vasc Biol 2018;38(6):1252-1254.
• Konstantinides SV. Diagnosis of Cerebral Venous Thrombosis: The Complementary Value of Imaging Methods. Thromb Haemost 2018;118(6):956.
• Huisman MV, Barco S, Cannegieter SC, Le Gal G, Konstantinides SV, Reitsma PH, Rodger M, Vonk Noordegraaf A, Klok FA. Pulmonary embolism. Nat Rev Dis Primers 2018;4:18028.
• Konstantinides SV. Detection and treatment of chronic thromboembolic pulmonary hypertension: Still a lot of homework to do. Hellenic J Cardiol 2018;59(1):24-25.
• Klok FA, Barco S, Konstantinides SV. Evaluation of VTE-BLEED for predicting intracranial or fatal bleeding in stable anticoagulated patients with venous thromboembolism. Eur Respir J 2018;51(4).
• Prochaska JH, Arnold N, Jünger C, Münzel T, Wild PS. [Prevention of cardiovascular diseases]. Herz 2018;43(1):87-100.
• Ascher S, Reinhardt C. The gut microbiota: An emerging risk factor for cardiovascular and cerebrovascular disease. Eur J Immunol 2018;48(4):564-575.
• Konstantinides SV, Barco S. Prevention of early complications and late consequences after acute pulmonary embolism: Focus on reperfusion techniques. Thromb Res 2018;164:163-169.
• Klok FA, Barco S. Follow-up after acute Pulmonary Embolism. Hamostaseologie 2018;38(1):22-32.
• Münzel T, Daiber A. Inorganic nitrite and nitrate in cardiovascular therapy: A better alternative to organic nitrates as nitric oxide donors? Vascul Pharmacol 2018;102:1-10.
• Münzel T, Daiber A. The potential of aldehyde dehydrogenase 2 as a therapeutic target in cardiovascular disease. Expert Opin Ther Targets 2018;22(3):217-231.
• Spronk HMH, Padro T, Siland JE, Prochaska JH, Winters J, van der Wal AC, Posthuma JJ, Lowe G, d'Alessandro E, Wenzel P, Coenen DM, Reitsma PH, Ruf W, van Gorp RH, Koenen RR, Vajen T, Alshaikh NA, Wolberg AS, Macrae FL, Asquith N, Heemskerk J, Heinzmann A, Moorlag M, Mackman N, van der Meijden P, Meijers JCM, Heestermans M, Renne T, Dolleman S, Chayoua W, Ariens RAS, Baaten CC, Nagy M, Kuliopulos A, Posma JJ, Harrison P, Vries MJ, Crijns H, Dudink E, Buller HR, Henskens YMC, Sjalander A, Zwaveling S, Erkuner O, Eikelboom JW, Gulpen A, Peeters F, Douxfils J, Olie RH, Baglin T, Leader A, Schotten U, Scaf B, van Beusekom HMM, Mosnier LO, van der Vorm L, Declerck P, Visser M, Dippel DWJ, Strijbis VJ, Pertiwi K, Ten Cate-Hoek AJ, Ten Cate H. Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2018;118(2):229-250.
• Barco S, Konstantinides S, Huisman MV, Klok FA. Diagnosis of recurrent venous thromboembolism. Thromb Res 2018;163:229-235.
• Subramaniam S, Scharrer I. Procoagulant activity during viral infections. Front Biosci (Landmark Ed) 2018;23:1060-1081.
• Khandagale A, Reinhardt C. Gut microbiota - architects of small intestinal capillaries. Front Biosci (Landmark Ed) 2018;23:752-766.

Editorials und Fachbeiträge 2018

• Konstantinides SV. Introduction to the Special Issue: 'Update on Pulmonary Embolism'. Hamostaseologie 2018;38(2):71-72.
• Kossmann S, Wenzel P. Under Pressure: A New Role for CD11c(+) Myeloid Cells in Hypertension. Hypertension 2018;71(4):557-558.
• Brandt M, Wenzel P. Alcohol puts the heart under pressure: Acetaldehyde activates a localized renin angiotensin aldosterone system within the myocardium in alcoholic cardiomyopathy. Int J Cardiol 2018;257:220-221.

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Originalartikel 2017

• Wilton P, Steidel M, Krczal G, Hermanns I, Pfützner A, Konnerth A, Boonrod K. Identification of Highly Specific scFvs against Total Adiponectin for Diagnostic Purposes. Biology (Basel) 2017;6(2).
• Wild J, Gori T, Münzel T, Wenzel P. Successful percutaneous coronary intervention for an in-stent chronic total occlusion in a patient with dextrocardia: a case report. BMC Cardiovasc Disord 2017;17(1):281.
• Lagrange J, Didelot M, Mohamadi A, Walton LA, Bloemen S, de Laat B, Louis H, Thornton SN, Derby B, Sherratt MJ, Feve B, Challande P, Akhtar R, Cruickshank JK, Lacolley P, Regnault V. Implication of Free Fatty Acids in Thrombin Generation and Fibrinolysis in Vascular Inflammation in Zucker Rats and Evolution with Aging. Front Physiol 2017;8:949.
• Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galiè N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Münzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV, Investigators P-. Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thromb Haemost 2017;117(12):2425-2434.
• Stetzenbach M, Schnorbus B, Sagoschen I, Bleser W, Legner D, Stürer A. [Acute Monkshood Intoxication Requiring Acute Resuscitation in Suicidal Intent]. Anasthesiol Intensivmed Notfallmed Schmerzther 2017;52(9):641-644.
• Seiler E, Limacher A, Mean M, Beer HJ, Osterwalder J, Frauchiger B, Righini M, Aschwanden M, Matter CM, Banyai M, Kucher N, Staub D, Lämmle B, Rodondi N, Squizzato A, Aujesky D. Derivation and validation of a novel bleeding risk score for elderly patients with venous thromboembolism on extended anticoagulation. Thromb Haemost 2017;117(10).
• Lankeit M, Krieg V, Hobohm L, Kölmel S, Liebetrau C, Konstantinides S, Hamm CW, Mayer E, Wiedenroth CB, Guth S. Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant 2017.
• Cheung YW, Barco S, Mathot RAA, van den Dool EJ, Stroobants AK, Serlie MJ, Middeldorp S, Coppens M. Pharmacokinetics of dabigatran etexilate and rivaroxaban in patients with short bowel syndrome requiring parenteral nutrition: The PDER PAN study. Thromb Res 2017;160:76-82.
• Barco S, Pomero F, Di Minno MND, Tamborini Permunian E, Malato A, Pasca S, Barillari G, Fenoglio L, Siragusa S, Di Minno G, Ageno W, Dentali F. Clinical course of patients with symptomatic isolated superficial vein thrombosis: the ICARO follow-up study. J Thromb Haemost 2017;15(11):2176-2183.
• Keller K, Beule J, Balzer JO, Dippold W. Renal function as a cofactor for risk stratification and short-term outcome in acute pulmonary embolism. Exp Gerontol 2017;100:11-16.
• Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. J Am Soc Nephrol 2017;28(11):3182-3189.
• Schnorbus B, Wiebe J, Capodanno D, Brugaletta S, Geraci S, Mehilli J, Latib A, Lesiak M, Jensen C, Mattesini A, Münzel T, Capranzano P, Di Mario C, Naber C, Araszkiewicz A, Colombo A, Caramanno G, Sabate M, Tamburino C, Nef H, Gori T. Twelve-month outcomes after bioresorbable vascular scaffold implantation in patients with acute coronary syndromes. Data from the European Multicenter GHOST-EU Extended Registry. EuroIntervention 2017;13(9):e1104-e1111.
• Müller-Calleja N, Hollerbach A, Hauser F, Canisius A, Orning C, Lackner KJ. Antiphospholipid antibody-induced cellular responses depend on epitope specificity : implications for treatment of antiphospholipid syndrome. J Thromb Haemost 2017;15(12):2367-2376.
• Beutel ME, Brähler E, Wiltink J, Michal M, Klein EM, Jünger C, Wild PS, Münzel T, Blettner M, Lackner K, Nickels S, Tibubos AN. Emotional and tangible social support in a German population-based sample: Development and validation of the Brief Social Support Scale (BS6). PLoS One 2017;12(10):e0186516.
• Schuster AK, Pfeiffer N, Nickels S, Schulz A, Wild PS, Blettner M, Lackner K, Beutel ME, Münzel T, Vossmerbaeumer U. Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study. J Ophthalmol 2017;2017:2190347.
• Steven S, Dib M, Roohani S, Kashani F, Münzel T, Daiber A. Time Response of Oxidative/Nitrosative Stress and Inflammation in LPS-Induced Endotoxaemia-A Comparative Study of Mice and Rats. Int J Mol Sci 2017;18(10).
• Nielsen AL, Sorensen AB, Holmberg HL, Gandhi PS, Karlsson J, Buchardt J, Lamberth K, Kjelgaard-Hansen M, Ley CD, Sorensen BB, Ruf W, Olsen OH, Ostergaard H. Engineering of a membrane-triggered activity switch in coagulation factor VIIa. Proc Natl Acad Sci U S A 2017;114(47):12454-12459.
• Jagodzinski A, Neumann JT, Ojeda F, Sorensen NA, Wild P, Münzel T, Zeller T, Westermann D, Blankenberg S. Cardiovascular Biomarkers in Hypertensive Patients with Medical Treatment-Results from the Randomized TEAMSTA Protect I Trial. Clin Chem 2017;63(12):1877-1885.
• Gowert NS, Krüger I, Klier M, Donner L, Kipkeew F, Gliem M, Bradshaw NJ, Lutz D, Köber S, Langer H, Jander S, Jurk K, Frotscher M, Korth C, Bock HH, Elvers M. Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions. Cell Signal 2017;40:210-221.
• Schuster AK, Pfeiffer N, Schulz A, Hoehn R, Ponto KA, Wild PS, Blettner M, Beutel ME, Lackner KJ, Münzel T, Mirshahi A. Refractive, corneal and ocular residual astigmatism: distribution in a German population and age-dependency - the Gutenberg health study. Graefes Arch Clin Exp Ophthalmol 2017;255(12):2493-2501.
• Jäckel S, Kiouptsi K, Lillich M, Hendrikx T, Khandagale A, Kollar B, Hörmann N, Reiss C, Subramaniam S, Wilms E, Ebner K, Brühl MV, Rausch P, Baines JF, Haberichter S, Lämmle B, Binder CJ, Jurk K, Ruggeri ZM, Massberg S, Walter U, Ruf W, Reinhardt C. Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2. Blood 2017;130(4):542-553.
• Höhn R, Mirshahi A, Nickels S, Schulz A, Wild PS, Blettner M, Pfeiffer N. Cardiovascular medication and intraocular pressure: results from the Gutenberg Health Study. Br J Ophthalmol 2017;101(12):1633-1637.
• Braenne I, Willenborg C, Tragante V, Kessler T, Zeng L, Reiz B, Kleinecke M, von Ameln S, Willer CJ, Laakso M, Wild PS, Zeller T, Wallentin L, Franks PW, Salomaa V, Dehghan A, Meitinger T, Samani NJ, Asselbergs FW, Erdmann J et al. (2017) A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors. Scientific reports 7: 10252
• Nickels S, Schuster AK, Singer S, Wild PS, Laubert-Reh D, Schulz A, Finger RP, Michal M, Beutel ME, Münzel T, Lackner KJ, Pfeiffer N (2017) The National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) - reference data from the German population-based Gutenberg Health Study (GHS). Health Qual Life Outcomes 15: 156
• Zeller T, Schurmann C, Schramm K, Müller C, Kwon S, Wild PS, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann JT, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel RB, Roden M et al. (2017) Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. Hypertension 70: 743-750
• Trinchero A, Schotten S, Lämmle B, Pitton MB (2017) May-Thurner syndrome: missed diagnosis and missed early treatment? Hamostaseologie 37: 184-185
• Hubert A, Bochenek ML, Schutz E, Gogiraju R, Münzel T, Schäfer K (2017) Selective Deletion of Leptin Signaling in Endothelial Cells Enhances Neointima Formation and Phenocopies the Vascular Effects of Diet-Induced Obesity in Mice. Arteriosclerosis, thrombosis, and vascular biology 37: 1683-1697
• Schütz E, Bochenek ML, Riehl DR, Bosmann M, Münzel T, Konstantinides S, Schäfer K (2017) Absence of transforming growth factor beta 1 in murine platelets reduces neointima formation without affecting arterial thrombosis. Thrombosis and haemostasis 117: 1782-1797
• Roewe J, Higer M, Riehl DR, Gericke A, Radsak MP, Bosmann M (2017) Neuroendocrine Modulation of IL-27 in Macrophages. Journal of immunology 199(7):2503-2514
• Kamikubo Y, Mendolicchio GL, Zampolli A, Marchese P, Rothmeier AS, Orje JN, Gale AJ, Krishnaswamy S, Gruber A, Ostergaard H, Petersen LC, Ruf W, Ruggeri ZM (2017) Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex. Blood 130: 1661-1670
• Alflen A, Prüfer S, Ebner K, Reuter S, Aranda Lopez P, Scharrer I, Banno F, Stassen M, Schild H, Jurk K, Bosmann M, Beckert H, Radsak MP (2017) ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis. Scientific reports 7: 7184
• Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C (2017) Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels. PloS one 12: e0183590
• Kiouptsi K, Gambaryan S, Walter E, Walter U, Jurk K, Reinhardt C (2017) Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation. Sci Rep. 7(1):7621
• Klier M, Gowert NS, Jäckel S, Reinhardt C, Elvers M (2017) Phospholipase D1 is a regulator of platelet-mediated inflammation. Cell Signal 38: 171-181
• Schulz A, Zöller D, Nickels S, Beutel ME, Blettner M, Wild PS, Binder H(2017) Simulation of complex data structures for planning of studies with focus on biomarker comparison. BMC Med Res Methodol 17: 90
• Grechowa I, Horke S, Wallrath A, Vahl CF, Dorweiler B (2017) Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK-CHOP branch of the unfolded protein response. FASEB journal 31: 3868-3881
• Mean M, Limacher A, Stalder O, Angelillo-Scherrer A, Alberio L, Fontana P, Beer HJ, Rodondi N, Lämmle B, Aujesky D (2017) Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients? Am J Med 130: 1220 e17-1220 e22
• Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al-Dabet MM, Manoharan J, Nazir S, Elwakiel A, Bock F, Kohli S, Marquardt A, Sögüt I, Shahzad K, Müller AJ, Esmon CT, Nawroth PP, Reiser J, Chavakis T, Ruf W, Isermann B (2017) Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. Blood 130: 1445-1455
• Chrysanthopoulou A, Kambas K, Stakos D, Mitroulis I, Mitsios A, Vidali V, Angelidou I, Bochenek M, Arelaki S, Arampatzioglou A, Galani IE, Skendros P, Couladouros EA, Konstantinides S, Andreakos E, Schäfer K, Ritis K (2017) Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation. J Pathol 243: 111-122
• Dentali F, Pegoraro S, Barco S, di Minno MND, Mastroiacovo D, Pomero F, Lodigiani C, Bagna F, Sartori M, Barillari G, Mumoli N, Napolitano M, Passamonti SM, Benedetti R, Ageno W, Di Nisio M (2017) Clinical course of isolated distal deep vein thrombosis in patients with active cancer: a multicenter cohort study. Journal of thrombosis and haemostasis 15: 1757-1763
• Fattahi F, Kalbitz M, Malan EA, Abe E, Jajou L, Huber-Lang MS, Bosmann M, Russell MW, Zetoune FS, Ward PA (2017) Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. FASEB journal 31(9):4129-4139
• Hoeper MM, Lam CS, Vachiery JL, Bauersachs J, Gerges C, Lang IM, Bonderman D, Olsson KM, Gibbs JS, Dorfmuller P, Guazzi M, Galie N, Manes A, Handoko ML, Vonk-Noordegraaf A, Lankeit M, Konstantinides S, Wachter R, Opitz C, Rosenkranz S (2017) Pulmonary hypertension in heart failure with preserved ejection fraction: a plea for proper phenotyping and further research. European heart journal 7;38(38):2869-2873
• Arnold N, Gori T, Schnabel RB, Schulz A, Prochaska JH, Zeller T, Binder H, Pfeiffer N, Beutel M, Espinola-Klein C, Lackner KJ, Blankenberg S, Münzel T, Wild PS (2017) Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study. Scientific reports 7: 6346
• Keller K, Stelzer K, Ostad MA, Post F (2017) Impact of exaggerated blood pressure response in normotensive individuals on future hypertension and prognosis: Systematic review according to PRISMA guideline. Advances in medical sciences 62: 317-329 
• Rukoyatkina N, Butt E, Subramanian H, Nikolaev VO, Mindukshev I, Walter U, Gambaryan S, Benz PM (2017) Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis. Cell Death Dis 8: e2898
• Ponto KA, Werner DJ, Wiedemer L, Laubert-Reh D, Schuster AK, Nickels S, Höhn R, Schulz A, Binder H, Beutel M, Lackner KJ, Wild PS, Pfeiffer N, Mirshahi A (2017) Retinal vessel metrics: normative data and their use in systemic hypertension: results from the Gutenberg Health Study. J Hypertens 35: 1635-1645
• Steven S, Oelze M, Hanf A, Kröller-Schön S, Kashani F, Roohani S, Welschof P, Kopp M, Godtel-Armbrust U, Xia N, Li H, Schulz E, Lackner KJ, Wojnowski L, Bottari SP, Wenzel P, Mayoux E, Münzel T, Daiber A (2017) The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats. Redox Biol 13: 370-385
• Rothmeier AS, Marchese P, Langer F, Kamikubo Y, Schaffner F, Cantor J, Ginsberg MH, Ruggeri ZM, Ruf W (2017) Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking. Arteriosclerosis, thrombosis, and vascular biology 37: 1323-1331
• Prochaska JH, Frank B, Nagler M, Lamparter H, Weisser G, Schulz A, Eggebrecht L, Göbel S, Arnold N, Panova-Noeva M, Hermanns I, Pinto A, Konstantinides S, Ten Cate H, Lackner KJ, Münzel T, Espinola-Klein C, Wild PS (2017) Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis. Scientific reports 7: 4591
• Prochaska JH, Göbel S, Keller K, Coldewey M, Ullmann A, Lamparter H, Schulz A, Schinzel H, Bickel C, Lauterbach M, Michal M, Hardt R, Binder H, Espinola-Klein C, Lackner KJ, Ten Cate H, Münzel T, Wild PS (2017) e-Health-based management of patients receiving oral anticoagulation therapy: results from the observational thrombEVAL study. Journal of thrombosis and haemostasis 15: 1375-1385
• Sag CM, Schnelle M, Zhang J, Murdoch CE, Kossmann S, Protti A, Santos CXC, Sawyer G, Zhang X, Mongue-Din H, Richards DA, Brewer AC, Prysyazhna O, Maier LS, Wenzel P, Eaton PJ, Shah AM (2017) Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure. Circulation 135: 2163-2177
• Barco S, Corti M, Trinchero A, Picchi C, Ambaglio C, Konstantinides SV, Dentali F, Barone M (2017) Survival and recurrent venous thromboembolism in patients with first proximal or isolated distal deep vein thrombosis and no pulmonary embolism. Journal of thrombosis and haemostasis 15: 1436-1442
• Kargapolova Y, Levin M, Lackner K, Danckwardt S (2017) sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs. Nucleic Acids Res 45: 6074-6086
• Klok FA, Barco S, Konstantinides SV (2017) External validation of the VTE-BLEED score for predicting major bleeding in stable anticoagulated patients with venous thromboembolism. Thrombosis and haemostasis 117: 1164-1170
• Mumoli N, Barco S, Cei M, Giorgi-Pierfranceschi M, Campanini M, Fontanella A, Ageno W, Dentali F (2017) Prevention and treatment of venous thromboembolism in patients with solid brain neoplasms: results of a survey among Italian physicians. Internal and emergency medicine 12: 437-443
• Sinning C, Ojeda F, Wild PS, Schnabel RB, Schwarzl M, Ohdah S, Lackner KJ, Pfeiffer N, Michal M, Blettner M, Münzel T, Kempf T, Wollert KC, Kuulasmaa K, Blankenberg S, Salomaa V, Westermann D, Zeller T (2017) Midregional proadrenomedullin and growth differentiation factor-15 are not influenced by obesity in heart failure patients. Clinical research in cardiology 106: 401-410
• Barco S, Atema JJ, Coppens M, Serlie MJ, Middeldorp S (2017) Anticoagulants for the prevention and treatment of catheter-related thrombosis in adults and children on parenteral nutrition: a systematic review and critical appraisal. Blood Transfus 15: 369-377
• Steven S, Jurk K, Kopp M, Kröller-Schön S, Mikhed Y, Schwierczek K, Roohani S, Kashani F, Oelze M, Klein T, Tokalov S, Danckwardt S, Strand S, Wenzel P, Münzel T, Daiber A (2017) Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice. British journal of pharmacology 174: 1620-1632
• Beutel ME, Klein EM, Brähler E, Reiner I, Jünger C, Michal M, Wiltink J, Wild PS, Münzel T, Lackner KJ, Tibubos AN (2017) Loneliness in the general population: prevalence, determinants and relations to mental health. BMC psychiatry 17: 97
• Brant LC, Wang N, Ojeda FM, LaValley M, Barreto SM, Benjamin EJ, Mitchell GF, Vasan RS, Palmisano JN, Münzel T, Blankenberg S, Wild PS, Zeller T, Ribeiro AL, Schnabel RB, Hamburg NM (2017) Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis. Journal of the American Heart Association 6
• Marx-Gross S, Laubert-Reh D, Schneider A, Höhn R, Mirshahi A, Münzel T, Wild PS, Beutel ME, Blettner M, Pfeiffer N (2017) The Prevalence of Glaucoma in Young People. Deutsches Arzteblatt international 114: 204-210
• Rose DM, Seidler A, Nübling M, Latza U, Brähler E, Klein EM, Wiltink J, Michal M, Nickels S, Wild PS, König J, Claus M, Letzel S, Beutel ME (2017) Associations of fatigue to work-related stress, mental and physical health in an employed community sample. BMC psychiatry 17: 167
• Schuster AK, Pfeiffer N, Schulz A, Nickels S, Höhn R, Wild PS, Blettner M, Münzel T, Beutel ME, Lackner KJ, Vossmerbaeumer U (2017) The impact of pseudophakia on vision-related quality of life in the general population - The Gutenberg Health Study. Aging  9: 1030-1040
• Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Volker U, Grossmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundstrom J, Minelli C, Ruggiero D et al. (2017) Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. The Journal of clinical investigation 127: 1798-1812
• Stein J, Steven S, Bros M, Sudowe S, Hausding M, Oelze M, Münzel T, Grabbe S, Reske-Kunz A, Daiber A (2017) Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide. Oxid Med Cell Longev 2017: 4157213
• Falter T, Schmitt V, Herold S, Weyer V, von Auer C, Wagner S, Hefner G, Beutel M, Lackner K, Lämmle B, Scharrer I (2017) Depression and cognitive deficits as long-term consequences of thrombotic thrombocytopenic purpura. Transfusion 57: 1152-1162
• Lorenz K, Scheller Y, Bell K, Grus F, Ponto KA, Bock F, Cursiefen C, Flach J, Gehring M, Peto T, Silva R, Tal Y, Pfeiffer N (2017) A prospective, randomised, placebo-controlled, double-masked, three-armed, multicentre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma - the STRONG study: study protocol for a randomised controlled trial. Trials 18: 128
• Steven S, Oelze M, Brandt M, Ullmann E, Kröller-Schön S, Heeren T, Tran LP, Daub S, Dib M, Stalleicken D, Wenzel P, Münzel T, Daiber A (2017) Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension. Oxid Med Cell Longev 2017: 4353462
• Luque Ramos A, Ohlmeier C, Enders D, Linder R, Horenkamp-Sonntag D, Prochaska JH, Mikolajczyk R, Garbe E (2017) Initiation and duration of dual antiplatelet therapy after inpatient percutaneous coronary intervention with stent implantation in Germany: An electronic healthcare database cohort study. Z Evid Fortbild Qual Gesundhwes 120: 31-38
• Panova-Noeva M, Arnold N, Hermanns MI, Prochaska JH, Schulz A, Spronk HM, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner KJ, Ten Cate H, Wild PS (2017) Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability. Scientific reports 7: 40229
• Magnussen C, Ojeda FM, Rzayeva N, Zeller T, Sinning CR, Pfeiffer N, Beutel M, Blettner M, Lackner KJ, Blankenberg S, Münzel T, Rabe KF, Wild PS, Schnabel RB, Gutenberg Health Study i (2017) FEV1 and FVC predict all-cause mortality independent of cardiac function - Results from the population-based Gutenberg Health Study. International journal of cardiology 234: 64-68
• de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, [...], Wild PS et al. (2017) Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PloS one 12: e0167742
• Springelkamp H, Iglesias AI, Mishra A, Hohn R, Wojciechowski R, Khawaja AP, Nag A, Wang YX, Wang JJ, Cuellar-Partida G, Gibson J, Bailey JN, Vithana EN, Gharahkhani P, Boutin T, Ramdas WD, Zeller T, Luben RN, Yonova-Doing E, Viswanathan A, […], Wild PS et al. (2017) New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Human molecular genetics 26: 438-453
• Sennblad B, Basu S, Mazur J, Suchon P, Martinez-Perez A, van Hylckama Vlieg A, Truong V, Li Y, Gadin JR, Tang W, Grossman V, de Haan HG, Handin N, Silveira A, Souto JC, Franco-Cereceda A, Morange PE, Gagnon F, Soria JM, Eriksson P, Hamsten A, Maegdefessel L, Rosendaal FR, Wild P, Folsom AR, Tregouet DA, Sabater-Lleal M (2017) Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels. Human molecular genetics 26: 637-649
• Loroch S, Trabold K, Gambaryan S, Reiss C, Schwierczek K, Fleming I, Sickmann A, Behnisch W, Zieger B, Zahedi RP, Walter U, Jurk K (2017) Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B. Thrombosis and haemostasis 117: 556-569
• Beck F, Geiger J, Gambaryan S, Solari FA, Dell'Aica M, Loroch S, Mattheij NJ, Mindukshev I, Potz O, Jurk K, Burkhart JM, Fufezan C, Heemskerk JW, Walter U, Zahedi RP, Sickmann A (2017) Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition. Blood 129: e1-e12
• Subramaniam S, Jurk K, Hobohm L, Jäckel S, Saffarzadeh M, Schwierczek K, Wenzel P, Langer F, Reinhardt C, Ruf W (2017) Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development. Blood 129: 2291-2302
• Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P (2017) Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension. Sci Transl Med 9
• Reiner MF, Akhmedov A, Stivala S, Keller S, Gaul DS, Bonetti NR, Savarese G, Glanzmann M, Zhu C, Ruf W, Yang Z, Matter CM, Luscher TF, Camici GG, Beer JH (2017) Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression. Cardiovascular research 113: 61-69
• Bochenek ML, Rosinus NS, Lankeit M, Hobohm L, Bremmer F, Schutz E, Klok FA, Horke S, Wiedenroth CB, Münzel T, Lang IM, Mayer E, Konstantinides S, Schäfer K (2017) From thrombosis to fibrosis in chronic thromboembolic pulmonary hypertension. Thrombosis and haemostasis 117: 769-783
• van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, [...] Wild PS, [...] et al. (2017) Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet 100: 51-63
• Panova-Noeva M, Arnold N, Hermanns MI, Prochaska JH, Schulz A, Spronk HM, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner KJ, Ten Cate H, Wild PS (2017) Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability. Scientific reports 7: 40229
• Busch CJ, Hendrikx T, Weismann D, Jäckel S, Walenbergh SM, Rendeiro AF, Weisser J, Puhm F, Hladik A, Göderle L, Papac-Milicevic N, Haas G, Millischer V, Subramaniam S, Knapp S, Bennett KL, Bock C, Reinhardt C, Shiri-Sverdlov R, Binder CJ (2017) Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. Hepatology 65: 1181-1195
• Konstantinides SV, Vicaut E, Danays T, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Dellas C, Duerschmied D, Empen K, Ferrari E, Galie N, Jimenez D, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N et al. (2017) Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. Journal of the American College of Cardiology 69: 1536-1544
• Müller-Calleja N, Manukyan D, Canisius A, Strand D, Lackner KJ (2017) Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase. Ann Rheum Dis 76: 891-897
• Sinning C, Kempf T, Schwarzl M, Lanfermann S, Ojeda F, Schnabel RB, Zengin E, Wild PS, Lackner KJ, Münzel T, Blankenberg S, Wollert KC, Zeller T, Westermann D (2017) Biomarkers for characterization of heart failure - Distinction of heart failure with preserved and reduced ejection fraction. International journal of cardiology 227: 272-277
• Faller N, Limacher A, Mean M, Righini M, Aschwanden M, Beer JH, Frauchiger B, Osterwalder J, Kucher N, Lämmle B, Cornuz J, Angelillo-Scherrer A, Matter CM, Husmann M, Banyai M, Staub D, Mazzolai L, Hugli O, Rodondi N, Aujesky D (2017) Predictors and Causes of Long-Term Mortality in Elderly Patients with Acute Venous Thromboembolism: A Prospective Cohort Study. Am J Med 130: 198-206
• Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H, International Working Group for Thrombotic Thrombocytopenic P (2017) Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies. Journal of thrombosis and haemostasis 15: 312-322
• Barco S, Picchi C, Trinchero A, Middeldorp S, Coppens M (2017) Safety of prothrombin complex concentrate in healthy subjects. Br J Haematol 176: 664-666
• Keller K, von Bardeleben RS, Ostad MA, Hobohm L, Münzel T, Konstantinides S, Lankeit M (2017) Temporal Trends in the Prevalence of Infective Endocarditis in Germany Between 2005 and 2014. Am J Cardiol 119: 317-322

Reviews 2017

• Lankeit M. Always think of the right ventricle, even in "low-risk" pulmonary embolism. Eur Respir J 2017;50(6).
• Lankeit M, Keller K, Tschöpe C, Pieske B. [Medicinal treatment of tricuspid valve regurgitation]. Herz 2017;42(7):634-643.
• Schönfelder T, Jäckel S, Wenzel P (2017) Mouse models of deep vein thrombosis. Gefasschirurgie 22: 28-33
• Schulman S, Ageno W, Konstantinides SV (2017) Venous thromboembolism: Past, present and future. Thrombosis and haemostasis 117: 1219-1229
• Schäfer K, Drosos I, Konstantinides S (2017) Perivascular adipose tissue: epiphenomenon or local risk factor? Int J Obes 41: 1311-1323
• Lackner KJ, Manukyan D, Müller-Calleja N (2017) Pathophysiological insights into the antiphospholipid syndrome. Hamostaseologie 37: 202-207
• Jurk K (2017) Platelet granules - secretory and secretive. Hamostaseologie 37(3):208-210
• Lutz J, Jurk K, Schinzel H (2017) Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations. Int J Nephrol Renovasc Dis 10: 135-143
• Konstantinides SV (2017) Diagnosis of pulmonary embolism: progress after many YEARS. Lancet 390: 210-211
• Lutz J, Jurk K (2017) Antiplatelet Agents and Anticoagulants in Patients with Chronic Kidney Disease - from Pathophysiology to Clinical Practice. Current pharmaceutical design 23: 1366-1376
• Scholz-Kreisel P, Spix C, Blettner M, Eckerle S, Faber J, Wild P, Merzenich H, Hennewig U (2017) Prevalence of cardiovascular late sequelae in long-term survivors of childhood cancer: A systematic review and meta-analysis. Pediatr Blood Cancer 64
• Lackner KJ, Manukyan D, Müller-Calleja N (2017) Endosomal Redox Signaling in the Antiphospholipid Syndrome. Curr Rheumatol Rep 19: 20
• Kremer Hovinga JA, Coppo P, Lämmle B, Moake JL, Miyata T, Vanhoorelbeke K (2017) Thrombotic thrombocytopenic purpura. Nat Rev Dis Primers 3: 17020
• Barco S, Konstantinides SV (2017) Catheter-directed thrombolysis for acute pulmonary embolism: Where do we stand? Lung India 34: 221-222
• Barco S, Konstantinides SV (2017) Risk-adapted management of pulmonary embolism. Thrombosis research 151 Suppl 1: S92-S96
• Wenzel P, Kossmann S, Münzel T, Daiber A (2017) Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species. Free Radic Biol Med 
• Lagrange J, Kossmann S, Wenzel P (2017) Assessment of Vascular Dysfunction and Inflammation Induced by Angiotensin II in Mice. Methods Mol Biol 1559: 439-453
• Konstantinides SV, Barco S (2017) Systemic Thrombolytic Therapy for Acute Pulmonary Embolism: Who Is a Candidate? Semin Respir Crit Care Med 38: 56-65
• Pagel O, Walter E, Jurk K, Zahedi RP (2017) Taking the stock of granule cargo: Platelet releasate proteomics. Platelets 28: 119-128
• Gori T, Grünewald J (2017) Clinical career and research: are they mutually exclusive? European heart journal 38: 72-74

Editorials und Fachbeiträge 2017

• Konstantinides SV. The Elusive Evidence for Inferior Vena Cava Filters to Prevent Pulmonary Embolism. J Am Coll Cardiol 2017;70(13):1598-1600.
• Reinhardt C (2017) GAS6: Pouring GASoline Into the Inflammatory Inferno of Venous Thrombosis. Arteriosclerosis, thrombosis, and vascular biology 37: 1263-1265
• Ruf W, Preissner KT (2017) State of the Art 2017. Journal of thrombosis and haemostasis 15: 1239
• Lämmle B (2017) Opana ER-induced thrombotic microangiopathy. Blood 129: 808-809

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Originalartikel 2016

• Yost CC, Schwertz H, Cody MJ, Wallace JA, Campbell RA, Vieira-de-Abreu A, Araujo CV, Schubert S, Harris ES, Rowley JW, Rondina MT, Fulcher JM, Koening CL, Weyrich AS, Zimmerman GA (2016) Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation. The Journal of clinical investigation 126: 3783-3798
• Klok FA, Hösel V, Clemens A, Yollo WD, Tilke C, Schulman S, Lankeit M, Konstantinides SV (2016) Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. The European respiratory journal 48: 1369-1376
• Barco S, Heuschen CB, Salman B, Brekelmans MP, Serlie MJ, Middeldorp S, Coppens M (2016) Home parenteral nutrition-associated thromboembolic and bleeding events: results of a cohort study of 236 individuals. Journal of thrombosis and haemostasis 14: 1364-73
• Barco S, Woersching AL, Spyropoulos AC, Piovella F, Mahan CE (2016) European Union-28: An annualised cost-of-illness model for venous thromboembolism. Thrombosis and haemostasis 115: 800-8
• Jankowiak S, Backé E, Liebers F, Schulz A, Hegewald J, Garthus-Niegel S, Nübling M, Blankenberg S, Pfeiffer N, Lackner KJ, Beutel M, Blettner M, Münzel T, Wild PS, Seidler A, Letzel S, Latza U (2016) Current and cumulative night shift work and subclinical atherosclerosis: results of the Gutenberg Health Study. International archives of occupational and environmental health 89: 1169-1182
• Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, Moretta A, Capaul R, Zbinden A, Ferlazzo G, Malmberg KJ, Chijioke O, Munz C (2016) Cognate HLA absence in trans diminishes human NK cell education. The Journal of clinical investigation 126: 3772-3782
• Schwarzl M, Ojeda F, Zeller T, Seiffert M, Becher PM, Münzel T, Wild PS, Blettner M, Lackner KJ, Pfeiffer N, Beutel ME, Blankenberg S, Westermann D (2016) Risk factors for heart failure are associated with alterations of the LV end-diastolic pressure-volume relationship in non-heart failure individuals: data from a large-scale, population-based cohort. European heart journal 37: 1807-14
• Kohli S, Ranjan S, Hoffmann J, Kashif M, Daniel EA, Al-Dabet MM, Bock F, Nazir S, Huebner H, Mertens PR, Fischer KD, Zenclussen AC, Offermanns S, Aharon A, Brenner B, Shahzad K, Ruebner M, Isermann B (2016) Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts. Blood 128: 2153-2164
• Mirshahi A, Ponto KA, Laubert-Reh D, Rahm B, Lackner KJ, Binder H, Pfeiffer N, Unterrainer JM (2016) Myopia and Cognitive Performance: Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci 57: 5230-5236
• Elflein HM, Rudy M, Lorenz K, Ponto KA, Scheurich A, Pitz S (2016) Charles Bonnet's syndrome: not only a condition of the elderly. Graefes Arch Clin Exp Ophthalmol 254: 1637-42
• Beutel ME, Jünger C, Klein EM, Wild P, Lackner KJ, Blettner M, Banerjee M, Michal M, Wiltink J, Brahler E (2016) Depression, anxiety and suicidal ideation among 1(st) and 2(nd) generation migrants - results from the Gutenberg health study. BMC psychiatry 16: 288
• Nagler M, Kremer Hovinga JA, Alberio L, Peter-Salonen K, von Tengg-Kobligk H, Lottaz D, Neerman-Arbez M, Lämmle B (2016) Thromboembolism in patients with congenital afibrinogenaemia. Long-term observational data and systematic review. Thrombosis and haemostasis 116: 722-32
• Luther N, Shahneh F, Brähler M, Krebs F, Jäckel S, Subramaniam S, Stanger C, Schönfelder T, Kleis-Fischer B, Reinhardt C, Probst HC, Wenzel P, Schäfer K, Becker C (2016) Innate Effector-Memory T Cell Activation Regulates Post-Thrombotic Vein Wall Inflammation and Thrombus Resolution. Circ Res 
• Elbaz H, Peto T, Butsch C, Orouji E, Laubert-Reh D, Ponto KA, Binder H, Pfeiffer N, Mirshahi A (2016) PREVALENCE AND ASSOCIATIONS OF MYELINATED RETINAL NERVE FIBERS: Results From the Population-Based Gutenberg Health Study. Retina
• Gogiraju R, Schroeter MR, Bochenek ML, Hubert A, Münzel T, Hasenfuss G, Schäfer K (2016) Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice. Cardiovascular research 111: 204-16
• Krüger M, Amort J, Wilgenbus P, Helmstädter JP, Grechowa I, Ebert J, Tenzer S, Moergel M, Witte I, Horke S (2016) The anti-apoptotic PON2 protein is Wnt/beta-catenin-regulated and correlates with radiotherapy resistance in OSCC patients. Oncotarget 
• Benz PM, Laban H, Zink J, Günther L, Walter U, Gambaryan S, Dib K (2016) Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets. Cell Commun Signal 14: 21
• Gambaryan S, Subramanian H, Kehrer L, Mindukshev I, Sudnitsyna J, Reiss C, Rukoyatkina N, Friebe A, Sharina I, Martin E, Walter U (2016) Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis. Cell Commun Signal 14: 16
• Keller K, Beule J, Balzer JO, Dippold W (2016) Right bundle branch block and SQ-type patterns for risk stratification in acute pulmonary embolism. Journal of electrocardiology 
• Keller K, Beule J, Balzer JO, Dippold W (2016) Syncope and collapse in acute pulmonary embolism. The American journal of emergency medicine 
• Keller K, Stelzer K, Münzel T, Ostad MA (2016) Hypertension is strongly associated with false-positive bicycle exercise stress echocardiography testing results. Blood pressure: 1-9
• Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gärtner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S. (2016) Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood 
• Baum C, Ojeda FM, Wild PS, Rzayeva N, Zeller T, Sinning CR, Pfeiffer N, Beutel M, Blettner M, Lackner KJ, Blankenberg S, Münzel T, Rabe KF, Schnabel RB, Gutenberg Health Study i (2016) Subclinical impairment of lung function is related to mild cardiac dysfunction and manifest heart failure in the general population. International journal of cardiology 218: 298-304
• Beutel ME, Jünger C, Klein EM, Wild P, Lackner K, Blettner M, Binder H, Michal M, Wiltink J, Brähler E, Münzel T (2016) Noise Annoyance Is Associated with Depression and Anxiety in the General Population- The Contribution of Aircraft Noise. PloS one 11: e0155357
• Blankenberg S, Salomaa V, Makarova N, Ojeda F, Wild P, Lackner KJ, Jorgensen T, Thorand B, Peters A, Nauck M, Petersmann A, Vartiainen E, Veronesi G, Brambilla P, Costanzo S, Iacoviello L, Linden G, Yarnell J, Patterson CC, Everett BM et al. (2016) Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium. European heart journal 
• Garthus-Niegel S, Hegewald J, Seidler A, Nubling M, Espinola-Klein C, Liebers F, Wild PS, Latza U, Letzel S (2016) The Gutenberg health study: associations between occupational and private stress factors and work-privacy conflict. Bmc Public Health 16: 192
• Garthus-Niegel S, Nubling M, Letzel S, Hegewald J, Wagner M, Wild PS, Blettner M, Zwiener I, Latza U, Jankowiak S, Liebers F, Seidler A (2016) Development of a mobbing short scale in the Gutenberg Health Study. International archives of occupational and environmental health 89: 137-46
• Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabasi AL, Loscalzo J (2016) Endophenotype Network Models: Common Core of Complex Diseases. Scientific reports 6: 27414
• Kaller CP, Debelak R, Kostering L, Egle J, Rahm B, Wild PS, Blettner M, Beutel ME, Unterrainer JM (2016) Assessing Planning Ability Across the Adult Life Span: Population-Representative and Age-Adjusted Reliability Estimates for the Tower of London (TOL-F). Archives of clinical neuropsychology 31: 148-64 
• Manukyan D, Rossmann H, Schulz A, Zeller T, Pfeiffer N, Binder H, Münzel T, Beutel ME, Müller-Calleja N, Wild PS, Lackner KJ (2016) Distribution of antiphospholipid antibodies in a large population-based German cohort. Clinical chemistry and laboratory medicine 54: 1663-70
• Müller-Calleja N, Rossmann H, Müller C, Wild P, Blankenberg S, Pfeiffer N, Binder H, Beutel ME, Manukyan D, Zeller T, Lackner KJ (2016) Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression. Thrombosis and haemostasis 116: 115-23
• Müller C, Schillert A, Rothemeier C, Tregouet DA, Proust C, Binder H, Pfeiffer N, Beutel M, Lackner KJ, Schnabel RB, Tiret L, Wild PS, Blankenberg S, Zeller T, Ziegler A (2016) Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data. PloS one 11: e0156594
• Ponto KA, Koenig J, Peto T, Lamparter J, Raum P, Wild PS, Lackner KJ, Pfeiffer N, Mirshahi A (2016) Prevalence of diabetic retinopathy in screening-detected diabetes mellitus: results from the Gutenberg Health Study (GHS). Diabetologia 59: 1913-9
• Schuster AK, Pfeiffer N, Nickels S, Schulz A, Höhn R, Wild PS, Binder H, Münzel T, Beutel ME, Vossmerbaeumer U (2016) Distribution of Anterior Chamber Angle Width and Correlation With Age, Refraction, and Anterior Chamber Depth-The Gutenberg Health Study. Invest Ophthalmol Vis Sci 57: 3740-6
• Unterrainer J, Michal M, Rahm B, Hadzibegovic J, Wild PS, Schulz A, Münzel T, Blettner M, Lackner K, Pfeiffer N, Blankenberg S, Denollet J, Beutel ME (2016) Association of Type D personality with cognitive functioning in individuals with and without cardiovascular disease - The Gutenberg Health Study. International journal of cardiology 214: 256-61
• Becattini C, Agnelli G, Lankeit M, Masotti L, Pruszczyk P, Casazza F, Vanni S, Nitti C, Kamphuisen P, Vedovati MC, De Natale MG, Konstantinides S (2016) Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model. The European respiratory journal 
• Bleker SM, Buchmuller A, Chauleur C, Ainle FN, Donnelly J, Verhamme P, Jacobsen AF, Ganzevoort W, Prins M, Beyer-Westendorf J, DeSancho M, Konstantinides S, Pabinger I, Rodger M, Decousus H, Middeldorp S (2016) Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the Highlow study, a randomised trial of two doses. Thrombosis research 144: 62-68
• Drosos I, Chalikias G, Pavlaki M, Kareli D, Epitropou G, Bougioukas G, Mikroulis D, Konstantinou F, Giatromanolaki A, Ritis K, Münzel T, Tziakas D, Konstantinides S, Schäfer K (2016) Differences between perivascular adipose tissue surrounding the heart and the internal mammary artery: possible role for the leptin-inflammation-fibrosis-hypoxia axis. Clinical research in cardiology : official journal of the German Cardiac Society 
• Kaymaz C, Öztürk S, Akbal Ö, Tanboga IH, Yilmaz F, Poci N, Türkday S, Hakgör A, Yildiz C, Aktemur T, Özdemir N, Konstantinides S (2016) Ultrasound-Assisted Catheter-Directed Thrombolysis in High-Risk and Intermediate-High-Risk Pulmonary Embolism: Results From a Single-Center Cohort. Angiology 
• Klok FA, Hösel V, Clemens A, Yollo WD, Tilke C, Schulman S, Lankeit M, Konstantinides SV (2016) Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. The European respiratory journal 
• Konstantinides SV, Barco S, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Heydenreich N, Hoeper MM, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C et al. (2016) Late outcomes after acute pulmonary embolism: rationale and design of FOCUS, a prospective observational multicenter cohort study. Journal of thrombosis and thrombolysis 
• Brandt M, Garlapati V, Oelze M, Sotiriou E, Knorr M, Kröller-Schön S, Kossmann S, Schönfelder T, Morawietz H, Schulz E, Schultheiss HP, Daiber A, Münzel T, Wenzel P (2016) NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy. Scientific reports 6: 32554
• Karbach SH, Schönfelder T, Brandao I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P (2016) Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction. Journal of the American Heart Association 5
• Steven S, Jurk K, Kopp M, Kröller-Schön S, Mikhed Y, Schwierczek K, Roohani S, Kashani F, Oelze M, Klein T, Tokalov S, Danckwardt S, Strand S, Wenzel P, Münzel T, Daiber A (2016) Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice. British journal of pharmacology
• Barco S, Lankeit M, Binder H, Schellong S, Christ M, Beyer-Westendorf J, Duerschmied D, Bauersachs R, Empen K, Held M, Schwaiblmair M, Fonseca C, Jimenez D, Becattini C, Quitzau K, Konstantinides S. Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial. Thrombosis and haemostasis 116. 2016.
• Ramuschkat M, Appelbaum S, Atzler D, Zeller T, Bauer C, Ojeda FM, Sinning CR, Hoffmann B, Lackner KJ, Boger RH, Wild PS, Münzel T, Blankenberg S, Schwedhelm E, Schnabel RB, Gutenberg Health Study I. ADMA, subclinical changes and atrial fibrillation in the general population. International journal of cardiology 203:640-646. 2016.
• Teumer A, Tin A, Sorice R, […], Wild PS, […], Fox CS, Pattaro C, Kottgen A. Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Diabetes 65:803-817. 2016.
• Baum C, Johannsen SS, Zeller T, Atzler D, Ojeda FM, Wild PS, Sinning CR, Lackner KJ, Gori T, Schwedhelm E, Boger RH, Blankenberg S, Münzel T, Schnabel RB, Gutenberg Health Study i. ADMA and arginine derivatives in relation to non-invasive vascular function in the general population. Atherosclerosis 244:149-156. 2016.
• Pattaro C, Teumer A, Gorski M, […], Wild PS, […], Kottgen A, Kao WH, Fox CS. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications 7:10023. 2016.
• de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, […], Smith NL, Strachan DP, Dehghan A. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Human molecular genetics 25:358-370. 2016.
• Xia N, Horke S, Habermeier A, Closs EI, Reifenberg G, Gericke A, Mikhed Y, Münzel T, Daiber A, Förstermann U, Li H. Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice. Arteriosclerosis, thrombosis, and vascular biology 36:78-85. 2016.
• Koc M, Kostrubiec M, Elikowski W, Meneveau N, Lankeit M, Grifoni S, Kuch-Wocial A, Petris A, Zaborska B, Stefanovic BS, Hugues T, Torbicki A, Konstantinides S, Pruszczyk P, Ri HI. Outcome of patients with right heart thrombi: the Right Heart Thrombi European Registry. The European respiratory journal 47:869-875. 2016.
• Hobohm L, Hellenkamp K, Hasenfuss G, Münzel T, Konstantinides S, Lankeit M. Comparison of risk assessment strategies for not-high-risk pulmonary embolism. The European respiratory journal 47:1170-1178. 2016.
• Jimenez D, Lobo JL, Fernandez-Golfin C, Portillo AK, Nieto R, Lankeit M, Konstantinides S, Prandoni P, Muriel A, Yusen RD, investigators P. Effectiveness of prognosticating pulmonary embolism using the ESC algorithm and the Bova score. Thrombosis and haemostasis 115:827-834. 2016.
• Manukyan D, Müller-Calleja N, Jäckel S, Luchmann K, Monnikes R, Kiouptsi K, Reinhardt C, Jurk K, Walter U, Lackner KJ. Cofactor-independent human antiphospholipid antibodies induce venous thrombosis in mice. Journal of thrombosis and haemostasis 14:1011-1020. 2016.
• von Krogh AS, Quist-Paulsen P, Waage A, Langseth OO, Thorstensen K, Brudevold R, Tjonnfjord GE, Largiader CR, Lämmle B, Kremer Hovinga JA. High prevalence of hereditary thrombotic thrombocytopenic purpura in central Norway: from clinical observation to evidence. Journal of thrombosis and haemostasis 14:73-82. 2016.
• Segna D, Mean M, Limacher A, Baumgartner C, Blum MR, Beer JH, Kucher N, Righini M, Matter CM, Frauchiger B, Cornuz J, Aschwanden M, Banyai M, Osterwalder J, Husmann M, Egloff M, Staub D, Lämmle B, Angelillo-Scherrer A, Aujesky D, Rodondi N. Association between thyroid dysfunction and venous thromboembolism in the elderly: a prospective cohort study. Journal of thrombosis and haemostasis. 14: 685-94. 2016.
• Insam C, Mean M, Limacher A, Angelillo-Scherrer A, Aschwanden M, Banyai M, Beer JH, Bounameaux H, Egloff M, Frauchiger B, Husmann M, Kucher N, Lämmle B, Matter C, Osterwalder J, Righini M, Staub D, Rodondi N, Aujesky D. Anticoagulation Management Practices and Outcomes in Elderly Patients with Acute Venous Thromboembolism: A Clinical Research Study. PloS one 11:e0148348. 2016.
• Fan X, Kremer Hovinga JA, Shirotani-Ikejima H, Eura Y, Hirai H, Honda S, Kokame K, Taleghani MM, von Krogh AS, Yoshida Y, Fujimura Y, Lämmle B, Miyata T. Genetic variations in complement factors in patients with congenital thrombotic thrombocytopenic purpura with renal insufficiency. International journal of hematology 103:283-291. 2016.

Reviews 2016

• Kiouptsi K, Reinhardt C (2016) Protein disulfide-isomerase - a trigger of tissue factor-dependent thrombosis. Clin Hemorheol Microcirc 64: 279-286
• Barco S (2016) Edoxaban for pulmonary embolism with right ventricular dysfunction. Lancet Haematol 3: e405-6
• Barco S, Serlie MJ, Coppens M (2016) Primary thromboprophylaxis for adult patients on home parenteral nutrition: A comment on the 2016 ESPEN guideline. Clin Nutr 35: 1579-1580
• Mahan CE, Barco S, Spyropoulos AC (2016) Cost-of-illness model for venous thromboembolism. Thrombosis research 145: 130-2
• Bochenek ML, Schutz E, Schäfer K (2016) Endothelial cell senescence and thrombosis: Ageing clots. Thrombosis research 147: 36-45
• Daiber A, Steven S, Weber A, Shuvaev VV, Muzykantov VR, Laher I, Li H, Lamas S, Münzel T (2016) Targeting vascular (endothelial) dysfunction. British journal of pharmacology
• Garn H, Bahn S, Baune BT, Binder EB, Bisgaard H, Chatila TA, Chavakis T, Culmsee C, Dannlowski U, Gay S, Gern J, Haahtela T, Kircher T, Müller-Ladner U, Neurath MF, Preissner KT, Reinhardt C, Rook G, Russell S, Schmeck B et al. (2016) Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. J Allergy Clin Immunol 138: 47-56
• Harjola VP, Mebazaa A, Celutkiene J, Bettex D, Bueno H, Chioncel O, Crespo-Leiro MG, Falk V, Filippatos G, Gibbs S, Leite-Moreira A, Lassus J, Masip J, Mueller C, Mullens W, Naeije R, Nordegraaf AV, Parissis J, Riley JP, Ristic A et al. (2016) Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology. European journal of heart failure 18: 226-41
• Konstantinides SV (2016) Trends in pregnancy outcomes in patients with pulmonary hypertension: still a long way to go. European journal of heart failure 18: 1129-31
• Sista AK, Goldhaber SZ, Vedantham S, Kline JA, Kuo WT, Kahn SR, Kabrhel C, McLaughlin VV, White SB, Kim NH, Gray M, Simon MA, Benenati JF, Misra S, Sterling KM, Kee ST, Konstantinides SV, Jaff MR, Kearon C (2016) Research Priorities in Submassive Pulmonary Embolism: Proceedings from a Multidisciplinary Research Consensus Panel. Journal of vascular and interventional radiology : JVIR 27: 787-94
• Ogorodnikov, A., Y. Kargapolova and S. Danckwardt (2016). Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end. Pflugers Arch 468(6): 993-1012.
• Ruf, W. (2016). Hemostasis keeps the stem cell niche in order. Blood 128(8): 1027-1029.
• Ruf W, Rothmeier AS, Graf C. Targeting clotting proteins in cancer therapy - progress and challenges. Thrombosis research 140 Suppl 1:S1-7. 2016.
• Ward PA, Fattahi F, Bosmann M. New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung. Frontiers in immunology 7:86. 2016.
• Krenzlin H, Lorenz V, Danckwardt S, Kempski O, Alessandri B. The Importance of Thrombin in Cerebral Injury and Disease. International journal of molecular sciences 17. 2016.
• Gur-Cohen S, Kollet O, Graf C, Esmon CT, Ruf W, Lapidot T. Regulation of long-term repopulating hematopoietic stem cells by EPCR/PAR1 signaling. Annals of the New York Academy of Sciences. 2016.
• Konstantinides SV, Barco S, Lankeit M, Meyer G. Management of Pulmonary Embolism: An Update. Journal of the American College of Cardiology 67:976-990. 2016.
• Lankeit M, Held M. Incidence of venous thromboembolism in COPD: linking inflammation and thrombosis? The European respiratory journal 47:369-373. 2016.
• Lämmle B. Thrombotic microangiopathy: Caplacizumab accelerates resolution of acute acquired TTP. Nature reviews. Nephrology 12:259-260. 2016.

Editorials und Fachbeiträge 2016

• Konstantinides SV. Trends in incidence versus case fatality rates of pulmonary embolism: Good news or bad news? Thrombosis and haemostasis 115:233-235. 2016.
• Konstantinides SV. Trends in Pulmonary Embolism Outcomes: Are We Really Making Progress? Journal of the American College of Cardiology 67:171-173. 2016.

• Isth Steering Committee for World Thrombosis Day (2016) Venous thromboembolism: A Call for risk assessment in all hospitalised patients. Thrombosis and haemostasis 116: 777-779
• Wilkens H, Konstantinides S, Lang I, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohe C, Guth S, Held M, Hinrichs J, Hoeper MM, Klepetko W, Kramm T, Kruger U, Lankeit M, Meyer BC, Olsson KM, Schafers HJ, Schmidt M et al. (2016) [Chronic thromboembolic pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016]. Deutsche medizinische Wochenschrift 141: S62-S69
• Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH et al. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. European heart journal

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Originalartikel 2015

• Atzler D, Appelbaum S, Cordts K, Ojeda FM, Wild PS, Münzel T, Blankenberg S, Boger RH, Blettner M, Beutel ME, Pfeiffer N, Zeller T, Lackner KJ, Schwedhelm E. Reference intervals of plasma homoarginine from the German Gutenberg Health Study. Clinical chemistry and laboratory medicine. 2015.
• Pfützner A, Hermanns I, Ramljak S, Demircik F, Pfützner AH, Kann PH, Weber MM. Elevated Intact Proinsulin Levels During an Oral Glucose Challenge Indicate Progressive ss-Cell Dysfunction and May Be Predictive for Development of Type 2 Diabetes. Journal of diabetes science and technology 9:1307-1312. 2015.
• Hauser F, Rossmann H, Laubert-Reh D, Wild PS, Zeller T, Müller C, Neuwirth S, Blankenberg S, Lackner KJ. Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene? Genes and immunity 16:571-575. 2015.
• Zeller T, Haase T, Müller C, Riess H, Lau D, Zeller S, Krause J, Baumert J, Pless O, Dupuis J, Wild PS, Eleftheriadis M, Waldenberger M, Zeilinger S, Ziegler A, Peters A, Tiret L, Proust C, Marzi C, Münzel T, Strauch K, Prokisch H, Lackner KJ, Herder C, Thorand B, Benjamin EJ, Blankenberg S, Koenig W, Schnabel RB. Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels. Circulation. Cardiovascular genetics 8:717-726. 2015.
• Homuth G, Wahl S, Muller C, [...], Wild PS, Ziegler A, Volker U, Prokisch H, Zeller T. Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts. BMC medical genomics 8:65. 2015. 
• Hasibeder A, Stein P, Brandwijk R, Schild H, Radsak MP. Evaluation and Validation of the Detection of soluble Triggering Receptor Expressed on Myeloid Cells 1 by Enzyme-linked immunosorbent Assay. Scientific reports 5:15381. 2015.
• Liang HP, Kerschen EJ, Basu S, Hernandez I, Zogg M, Jia S, Hessner MJ, Toso R, Rezaie AR, Fernandez JA, Camire RM, Ruf W, Griffin JH, Weiler H. Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice. Blood 126:2415-2423. 2015.
• Schnabel RB, Wild PS, Prochaska JH, Ojeda FM, Zeller T, Rzayeva N, Ebrahim A, Lackner KJ, Beutel ME, Pfeiffer N, Sinning CR, Oertelt-Prigione S, Regitz-Zagrosek V, Binder H, Münzel T, Blankenberg S, Gutenberg Health Study I. Sex Differences in Correlates of Intermediate Phenotypes and Prevalent Cardiovascular Disease in the General Population. Frontiers in cardiovascular medicine 2:15. 2015.
• Cohen SG, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, Ruf W, Lapidot T. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nature medicine. 21:1307-1317. 2015.
• Hellenkamp K, Schwung J, Rossmann H, Kaeberich A, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Risk stratification of normotensive pulmonary embolism: prognostic impact of copeptin. The European respiratory journal. 2015.
• Klok FA, Dzikowska-Diduch O, Kostrubiec M, Vliegen HW, Pruszczyk P, Hasenfuss G, Huisman MV, Konstantinides S, Lankeit M. Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. Journal of thrombosis and haemostasis : JTH. 2015.
• Ponto KA, Binder H, Diana T, Matheis N, Otto AF, Pitz S, Pfeiffer N, Kahaly GJ. Prevalence, Phenotype, and Psychosocial Well-Being in Euthyroid/Hypothyroid Thyroid-Associated Orbitopathy. Thyroid. 25:942-948. 2015.
• Keller K, Prochaska JH, Coldewey M, Gobel S, Ullmann A, Jünger C, Lamparter H, Ariza L, Bickel C, Lauterbach M, Konstantinides S, Rostock T, Münzel T, Wild PS. History of deep vein thrombosis is a discriminator for concomitant atrial fibrillation in pulmonary embolism. Thrombosis research 136:899-906. 2015.
• Panova-Noeva M, Schulz A, Hermanns I, Grossmann V, Pefani E, Spronk H, Laubert-Reh D, Binder H, Beutel M, Pfeiffer N, Blankenberg S, Zeller T, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Sex specific differences in genetic and non-genetic determinants of mean platelet volume: results from the Gutenberg Health Study. Blood. 2015.
• Larmann J, Jurk K, Janssen H, Müller M, Herzog C, Lorenz A, Schmitz M, Nofer JR, Theilmeier G. Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice. PloS one 10:e0131854. 2015.
• Wenzel P, Rossmann H, Müller C, Kossmann S, Oelze M, Schulz A, Arnold N, Simsek C, Lagrange J, Klemz R, Schönfelder T, Brandt M, Karbach SH, Knorr M, Finger S, Neukirch C, Häuser F, Beutel ME, Kröller-Schön S, Schulz E, Schnabel RB, Lackner K, Wild PS, Zeller T, Daiber A, Blankenberg S, Münzel T. Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans. European heart journal. 2015.
• Reiss C, Mindukshev I, Bischoff V, Subramanian H, Kehrer L, Friebe A, Stasch JP, Gambaryan S, Walter U. The sGC stimulator Riociguat inhibits platelet function in washed platelets but not in whole blood. British journal of pharmacology, 2015.
• Larmann J, Jurk K, Janssen H, Müller M, Herzog C, Lorenz A, Schmitz M, Nofer JR, Theilmeier G. Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice. PloS one. 10:e0131854, 2015.
• Jacobsen C, Oechsle K, Hauschild J, Steinemann G, Spath B, Bokemeyer C, Ruf W, Honecker F, Langer F. Regulation of tissue factor in NT2 germ cell tumor cells by cisplatin chemotherapy. Thrombosis research, 2015.
• Reiss C, Mindukshev I, Bischoff V, Subramanian H, Kehrer L, Friebe A, Stasch JP, Gambaryan S, Walter U. The sGC stimulator Riociguat inhibits platelet function in washed platelets but not in whole blood. British journal of pharmacology, 2015.
• Höhn R, Kottler U, Peto T, Blettner M, Münzel T, Blankenberg S, Lackner KJ, Beutel M, Wild PS, Pfeiffer N. The ophthalmic branch of the Gutenberg Health Study: study design, cohort profile and self-reported diseases. PloS one. 10:e0120476, 2015.
• Elflein HM, Fresenius S, Lamparter J, Pitz S, Pfeiffer N, Binder H, Wild P, Mirshahi A. The prevalence of amblyopia in Germany: data from the prospective, population-based Gutenberg Health Study. Deutsches Ärzteblatt international 112:338-344, 2015.
• Ding J, Reynolds LM, Zeller T, Müller C, Mstat KL, Nicklas BJ, Kritchevsky SB, Huang Z, Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Ida Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR, Jr., Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y.  Alterations of a cellular cholesterol metabolism network is a molecular feature of obesity-related type 2 diabetes and cardiovascular disease. Diabetes, 2015.
• Wendelboe AM, McCumber M, Hylek EM, Buller H, Weitz JI, Raskob G, Day ISCfWT. 2015. Global public awareness of venous thromboembolism. Journal of thrombosis and haemostasis : JTH 13:1365-1371, 2015.
• Gori T, Wild PS, Schnabel R, Schulz A, Pfeiffer N, Blettner M, Beutel ME, Forconi S, Jung F, Lackner KJ, Blankenberg S, Münzel T. The distribution of whole blood viscosity, its determinants and relationship with arterial blood pressure in the community: cross-sectional analysis from the Gutenberg Health Study. Therapeutic advances in cardiovascular disease, 2015.
• Demircik F, Ramljak S, Hermanns I, Pfützner A, Pfützner A. Evaluation of hematocrit interference with MyStar extra and seven competitive devices. Journal of diabetes science and technology. 9:262-267, 2015.
• Jabs A, Oelze M, Mikhed Y, Stamm P, Kröller-Schön S, Welschof P, Jansen T, Hausding M, Kopp M, Steven S, Schulz E, Stasch JP, Münzel T, Daiber A. Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats. Vascular pharmacology, 2015.
• Steven S, Hausding M, Kröller-Schön S, Mader M, Mikhed Y, Stamm P, Zinssius E, Pfeffer A, Welschof P, Agdauletova S, Sudowe S, Li H, Oelze M, Schulz E, Klein T, Münzel T, Daiber A. Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia. Basic research in cardiology. 110:6, 2015.
• Horke S, Xiao J, Schutz EM, Kramer GL, Wilgenbus P, Witte I, Selbach M, Teiber JF. A novel paraoxonase 2-dependent mechanism mediating the biological effects of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone. Infection and immunity, 2015.
• Hermanns MI, Grossmann V, Spronk HM, Schulz A, Junger C, Laubert-Reh D, Mazur J, Gori T, Zeller T, Pfeiffer N, Beutel M, Blankenberg S, Münzel T, Lackner KJ, Ten Cate-Hoek AJ, Ten Cate H, Wild PS. Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study. International journal of cardiology. 187:166-174, 2015.
• Krüger M, Pabst AM, Al-Nawas B, Horke S, Moergel M. Paraoxonase-2 (PON2) protects oral squamous cell cancer cells against irradiation-induced apoptosis. Journal of cancer research and clinical oncology, 2015.
• Hinkel R, Lange P, Petersen B, Gottlieb E, Ng JK, Finger S, Horstkotte J, Lee S, Thormann M, Knorr M, El-Aouni C, Boekstegers P, Reichart B, Wenzel P, Niemann H, Kupatt C. Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation: An Experimental Study in a Pre-Clinical Pig Model. Journal of the American College of Cardiology. 66:154-165, 2015.
• von Krogh AS, Kremer Hovinga JA, Romundstad PR, Roten LT, Lämmle B, Waage A, Quist-Paulsen P. ADAMTS13 gene variants and function in women with preeclampsia: A population- based nested case- control study from the HUNT Study. Thrombosis research, 14: 73-82. 2015.
• Raum P, Lamparter J, Ponto KA, Peto T, Hoehn R, Schulz A, Schneider A, Wild PS, Pfeiffer N, Mirshahi A. Prevalence and Cardiovascular Associations of Diabetic Retinopathy and Maculopathy: Results from the Gutenberg Health Study. PloS one. 10:e0127188, 2015.
  • Correction
• Gogiraju R, Xu X, Bochenek ML, Steinbrecher JH, Lehnart SE, Wenzel P, Kessel M, Zeisberg EM, Dobbelstein M, Schäfer K. Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice. Journal of the American Heart Association 4, 2015.
• Frank B, Ariza L, Lamparter H, Grossmann V, Prochaska JH, Ullmann A, Kindler F, Weisser G, Walter U, Lackner KJ, Espinola-Klein C, Munzel T, Konstantinides SV, Wild PS, group VTs. Rationale and design of three observational, prospective cohort studies including biobanking to evaluate and improve diagnostics, management strategies and risk stratification in venous thromboembolism: the VTEval Project. BMJ open 5:e008157, 2015.
• Klok FA, Niemann C, Dellas C, Hasenfuss G, Konstantinides S, Lankeit M. Performance of five different bleeding-prediction scores in patients with acute pulmonary embolism. Journal of thrombosis and thrombolysis, 2015.
• Stakos DA, Kambas K, Konstantinidis T, Mitroulis I, Apostolidou E, Arelaki S, Tsironidou V, Giatromanolaki A, Skendros P, Konstantinides S, Ritis K. Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction. European heart journal 36:1405-1414, 2015.
• Ponto KA, Elbaz H, Peto T, Laubert-Reh D, Binder H, Wild PS, Lackner K, Pfeiffer N, Mirshahi A. Prevalence and risk factors of retinal vein occlusion: the Gutenberg Health Study.  J Thromb Haemost. 13:1254-1263, 2015.
• Grossmann V, Schmitt VH, Zeller T, Panova-Noeva M, Schulz A, Laubert-Reh D, Juenger C, Schnabel RB, Abt TG, Laskowski R, Wiltink J, Schulz E, Blankenberg S, Lackner KJ, Münzel T, Wild PS. Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes. Diabetis care. pii: dc143008, 2015.
• Russkamp NF, Ruemmler R, Roewe J, Moore BB, Ward PA, Bosmann M. Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin. FASEB journal pii: fj.15-271635, 2015.
• Bollmann F*, Jäckel S*, Schmidtke L, Schrick K, Reinhardt C, Jurk K, Wu Z, Xia N, Li H, Erkel G, Walter U, Kleinert H**, Pautz A**. Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice. PloS one. 10:e0130401, 2015.
• Müller-Calleja N, Kohler A, Siebald B, Canisius A, Orning C, Radsak M, Stein P, Monnikes R, Lackner KJ. Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: implications for the antiphospholipid syndrome. Thrombosis and haemostasis 113, 2015.
• Michal M, Prochaska JH, Keller K, Göbel S, Coldewey M, Ullmann A, Schulz A, Lamparter H, Münzel T, Reiner I, Beutel ME, Wild PS. Symptoms of depression and anxiety predict mortality in patients undergoing oral anticoagulation: Results from the thrombEVAL study program. International journal of cardiology 187:614-619, 2015.
• Zolfaghari S, Harenberg J, Frölich L, Weiss C, Wehling M, Wild P, Prochaska J, Beyer-Westendorf J, Koscielny J, Lip GY. Development of recommendations to continue anticoagulation with one of the two types of oral anticoagulants based on the identification of patients' preference. Seminars in thrombosis and hemostasis 41:166-177, 2015.
• Wu Z, Siuda D, Xia N, Reifenberg G, Daiber A, Münzel T, Förstermann U, Li H. Maternal treatment of spontaneously hypertensive rats with pentaerythritol tetranitrate reduces blood pressure in female offspring. Hypertension. 65:232-237, 2015.
  • DZHK-Paper of the month: Januar 2015
  • DZHK Pressemitteilung
• Taddonio MA, Dolgachev V, Bosmann M, Ward PA, Su G, Wang SC, Hemmila MR. Influence of Lipopolysaccharide Binding Protein on Pulmonary Inflammation in Gram-negative Pneumonia. Shock. 2015.
• Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB journal. pii: fj.14-268730, 2015.
• Henninger C, Huelsenbeck S, Wenzel P, Brand M, Huelsenbeck J, Schad A, Fritz G. Chronic heart damage following doxorubicin treatment is alleviated by lovastatin. Pharmacological research. 91:47-56, 2015.
• Prochaska JH, Gobel S, Keller K, Coldewey M, Ullmann A, Lamparter H, Junger C, Al-Bayati Z, Baer C, Walter U, Bickel C, Ten Cate H, Munzel T, Wild PS. Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service inverted question mark results from the prospective, multi-center, observational cohort study thrombEVAL. BMC medicine. 13:14, 2015.
• Kaeberich A, Seeber V, Jimenez D, Kostrubiec M, Dellas C, Hasenfuss G, Giannitsis E, Pruszczyk P, Konstantinides S, Lankeit M. Age-adjusted hsTnT cut-off value for risk stratification of pulmonary embolism. The European respiratory journal. 2015.
• Kurmann R, Weisstanner C, Kardas P, Hirsch HH, Wiest R, Lämmle B, Furrer H, Du Pasquier R, Bassetti CL, Sturzenegger M, Krestel H. Progressive multifocal leukoencephalopathy in common variable immunodeficiency: mitigated course under mirtazapine and mefloquine. Journal of neurovirology, 21: 694-701. 2015.
• von Känel R, Margani A, Stauber S, Meyer FA, Demarmels Biasiutti F, Vökt F, Wissmann T, Lämmle B, Lukas PS. Depressive symptoms as a novel risk factor for recurrent venous thromboembolism: a longitudinal observational study in patients referred for thrombophilia investigation. PloS one 10:e0125858, 2015.
• Brandao I, Hörmann N, Jäckel S, Reinhardt C. TLR5 expression in the small intestine depends on the adaptors MyD88 and TRIF, but is independent of the enteric microbiota. Gut microbes:1-5, 2015.
• Schnabel RB, Johannsen SS, Wild PS, Blankenberg S. [Prevalence and risk factors of atrial fibrillation in Germany : data from the Gutenberg Health Study]. Herz 40:8-15, 2015.
• Rothmeier AS, Marchese P, Petrich BG, Furlan-Freguia C, Ginsberg MH, Ruggeri ZM, Ruf W. Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. The Journal of clinical investigation. 125:1471-1484, 2015.
• Klok FA, Tesche C, Rappold L, Dellas C, Hasenfuss G, Huisman MV, Konstantinides S, Lankeit M. External validation of a simple non-invasive algorithm to rule out chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. Thrombosis research 135:796-801, 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Modified Bova score for risk stratification and short-term outcome in acute pulmonary embolism. The Netherlands journal of medicine 73:410-416. 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Blood pressure for outcome prediction and risk stratification in acute pulmonary embolism. The American journal of emergency medicine 33:1617-1621. 2015.
• Keller K, Beule J, Coldewey M, Geyer M, Balzer JO, Dippold W. The risk factor age in normotensive patients with pulmonary embolism: Effectiveness of age in predicting submassive pulmonary embolism, cardiac injury, right ventricular dysfunction and elevated systolic pulmonary artery pressure in normotensive pulmonary embolism patients. Experimental gerontology 69:116-121. 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Typical symptoms for prediction of outcome and risk stratification in acute pulmonary embolism. International angiology. 2015.
• Keller K, Beule J, Schulz A, Coldewey M, Dippold W, Balzer JO. D-dimer for risk stratification in haemodynamically stable patients with acute pulmonary embolism. Advances in medical sciences 60:204-210. 2015.
• Keller K, Beule J, Coldewey M, Dippold W, Balzer JO. Heart rate in pulmonary embolism. Internal and emergency medicine 10:663-669. 2015.
• Keller K, Geyer M, Beule J, Coldewey M, Balzer JO, Dippold W. Impact of cancer on the effectiveness of cardiac Troponin I to predict right ventricular dysfunction in acute pulmonary embolism. Thoracic cancer 6:584-588. 2015.
• Keller K, Beule J, Coldewey M, Dippold W, Balzer JO. Impact of advanced age on the severity of normotensive pulmonary embolism. Heart and vessels 30:647-656. 2015.
• Keller K, Beule J, Schulz A, Coldewey M, Dippold W, Balzer JO. Cardiac troponin I for predicting right ventricular dysfunction and intermediate risk in patients with normotensive pulmonary embolism. Netherlands heart journal 23:55-61. 2015.

Reviews 2015

• Hahn SA, Bellinghausen I, Trinschek B, Becker C. Translating Treg Therapy in Humanized Mice. Frontiers in immunology 6:623. 2015.
• Daiber A, Di Lisa F, Oelze M, Kröller-Schön S, Steven S, Schulz E, Münzel T. Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function. British journal of pharmacology. 2015.
• van der Meijden PE, Ozaki Y, Ruf W, de Laat B, Mutch N, Diamond S, Nieuwland R, Peters TC, Heestermans M, Kremers RM, Moorlag M, Boender J, Unlu B, Reitsma PH. Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome). Thrombosis research. 136 Suppl 1:S3-7. 2015.
• Comerota AJ, Sandset PM, Konstantinides S, de Graaf R, Wakefield TW, Arnoldussen CW, Lam YL, van Gent WB, de Wolf MA, Catarinella FS, Kurstjens RL, Alshabatat A, Wittens CH. Theme 4: Invasive management of (recurrent) VTE and PTS. Thrombosis research 136 Suppl 1:S19-25. 2015.
• Konstantinides S. [Coronary heart disease: Genetic score identifies risk patients]. Deutsche medizinische Wochenschrift 140:1418.
• Hellenkamp K, Schwung J, Rossmann H, Kaeberich A, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Risk stratification of normotensive pulmonary embolism: prognostic impact of copeptin. The European respiratory journal. 2015.
• Grove EL, Lankeit M, Hess K, Freynhofer M, Stojkovic S, Varenhorst C, Thomas M. CardioPulse: the 'Young Thrombosis Researchers Group' of the ESC Working Group on Thrombosis. European heart journal. 36:703-704, 2015.
• Steven S, Münzel T, Daiber A. Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular Disease. International journal of molecular sciences. 16:18185-18223, 2015.
• Ruf W. Diverse packaging of TF into platelets. Thrombosis and haemostasis. 114, 2015.
• Mikhed Y, Daiber A, Steven S. Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction. International journal of molecular sciences. 16:15918-15953, 2015.
• Wärntges S, Konstantinides SV. Progress in the management of acute pulmonary embolism. Current opinion in pulmonary medicine, 2015.
• Klok FA, Meyer G, Konstantinides S. Management of intermediate-risk pulmonary embolism: uncertainties and challenges. http://www.ncbi.nlm.nih.gov/pubmed/26109174European journal of haematology, 2015.
• Konstantinides SV, Wärntges S. Acute phase treatment of venous thromboembolism: advanced therapy. Systemic fibrinolysis and pharmacomechanical therapy. Thrombosis and haemostasis 113, 2015.
• Ruf W, Samad F. Tissue factor pathways linking obesity and inflammation. Hamostaseologie 35, 2015.
• Klok FA, Kooiman J, Huisman MV, Konstantinides S, Lankeit M. Predicting anticoagulant-related bleeding in patients with venous thromboembolism: a clinically oriented review. The European respiratory journal. 45:201-210, 2015.
• Lämmle B. VWF and complement. Blood. 125:896-898, 2015.
• von Auer C, von Krogh AS, Kremer Hovinga JA, Lämmle B. Current insights into thrombotic microangiopathies: Thrombotic thrombocytopenic purpura and pregnancy. Thrombosis research 135 Suppl 1:S30-33, 2015.
• Kruger P, Saffarzadeh M, Weber AN, Rieber N, Radsak M, von Bernuth H, Benarafa C, Roos D, Skokowa J, Hartl D. Neutrophils: Between host defence, immune modulation, and tissue injury. PLoS pathogens 11:e1004651, 2015.
• Keller K, Engelhardt M. [Historical Changes in Meniscus Surgery--The Changing Appreciation of Disease, Surgical Techniques and Complications]. Zeitschrift fur Orthopadie und Unfallchirurgie 153:259-266. 2015.

Editorials und Fachbeiträge 2015

• Konstantinides SV, Lankeit M, Wild P, Quitzau K, Binder H, im Auftrag der F-I. [Follow-up after acute pulmonary embolism. A prospective non-interventional multi-center cohort study (FOCUS)]. Deutsche medizinische Wochenschrift. 140 Suppl 1:S20-21, 2015.

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Originalartikel 2014

• Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Nunez G, Muller M, Murray PJ, Ward PA. Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3. Journal of immunology. 193:5668-5677, 2014.
• Oelze M, Kroller-Schon S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Munzel T, Daiber A. Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging. Hypertension. 63:390-396, 2014.
• Zeller T, Ojeda F, Brunner FJ, Peitsmeyer P, Munzel T, Binder H, Pfeiffer N, Michal M, Wild PS, Blankenberg S, Lackner KJ. High-sensitivity cardiac troponin I in the general population - defining reference populations for the determination of the 99th percentile in the Gutenberg Health Study. Clinical chemistry and laboratory medicine. 2014.
• Wiltink J, Michal M, Wild PS, Schneider A, Konig J, Blettner M, Munzel T, Schulz A, Weber M, Fottner C, Pfeiffer N, Lackner K, Beutel ME. Associations between depression and diabetes in the community: do symptom dimensions matter? Results from the Gutenberg Health Study. PloS one 9:e105499, 2014.
• Schnabel RB, Wild PS, Wilde S, Ojeda FM, Schulz A, Zeller T, Sinning CR, Kunde J, Lackner KJ, Munzel T, Blankenberg S. Multiple biomarkers and atrial fibrillation in the general population. PloS one. 9:e11248, 2014.
• Michal M, Wiltink J, Kirschner Y, Schneider A, Wild PS, Munzel T, Blettner M, Schulz A, Lackner K, Pfeiffer N, Blankenberg S, Tschan R, Tuin I, Beutel ME. Complaints of sleep disturbances are associated with cardiovascular disease: results from the Gutenberg Health Study. PloS one. 9:e104324, 2014.
• Michal M, Prochaska JH, Ullmann A, Keller K, Gobel S, Coldewey M, Munzel T, Wiltink J, Beutel ME, Wild PS. Relevance of depression for anticoagulation management in a routine medical care setting: Results from the ThrombEVAL study program. Journal of thrombosis and haemostasis. 2014.
• Luneburg N, Lieb W, […], Wild PS, […], Vasan RS, Boger RH. Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine. Circulation. Cardiovascular genetics. 2014.
• Karbach S, Croxford AL, Oelze M, Schuler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reissig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E, Wenzel P, Waisman A, Munzel T. Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. Arteriosclerosis, thrombosis, and vascular biology. 34:2658-2668, 2014.
• Engelhardt B, Konig J, Blettner M, Wild P, Munzel T, Lackner K, Blankenberg S, Pfeiffer N, Beutel M, Zwiener I. 2014. Combining cross-sectional data on prevalence with risk estimates from a prediction model. A novel method for estimating the attributable risk. Methods of information in medicine. 53:371-379, 2014.
• Beygui F, Wild PS, Zeller T, Germain M, Castagne R, Lackner KJ, Munzel T, Montalescot G, Mitchell GF, Verwoert GC, Tarasov KV, Tregouet DA, Cambien F, Blankenberg S, Tiret L. Adrenomedullin and arterial stiffness: integrative approach combining monocyte ADM expression, plasma MR-Pro-ADM, and genome-wide association study. Circulation. Cardiovascular genetics. 7:634-641, 2014.
• Hörmann N, Brandao I, Jäckel S, Ens N, Lillich M, Walter U, Reinhardt C. Gut microbial colonization orchestrates TLR2 expression, signaling and epithelial proliferation in the small intestinal mucosa. PloS one. 9:e113080, 2014.
• Kossmann S, Hu H, Steven S, Schönfelder T, Fraccarollo D, Mikhed Y, Brähler M, Knorr M, Brandt M, Karbach SH, Becker C, Oelze M, Bauersachs J, Widder J, Münzel T, Daiber A, Wenzel P. Inflammatory Monocytes Determine Endothelial Nitric Oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II. Journal of Biological Chemistry. pii: jbc.M114.604231, 2014.
• Zeller T, Keller T, Ojeda F, Reichlin T, Twerenbold R, Tzikas S, Wild PS, Reiter M, Czyz E, Lackner KJ, Munzel T, Mueller C, Blankenberg S. Assessment of microRNAs in patients with unstable angina pectoris. European Heart Journal. 35(31):2106-14, 2014.
• Weber M, Rudolph B, Stein P, Yogev N, Bosmann M, Schild H, Radsak MP. Host-derived CD8+ dendritic cells protect against acute Graft-versus-Host Disease after experimental allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation. pii: S1083-8791(14)00504-7, 2014.
• Dorweiler B, Grechowa I, Wallrath A, Vahl CF, Horke S. Activation of the pro-apoptotic unfolded protein response in plaques of the human carotid artery. European Journal of Vascular and Endovascular Surgery. pii: S1078-5884(14)00357-8, 2014. 
• Ponto KA, Zwiener I, Al-Nawas B, Kahaly GJ, Otto AF, Karbach J. Piezosurgery for Orbital Decompression Surgery in Thyroid Associated Orbitopathy. Journal of Cranio-Maxillofacial Surgery. pii: S1010-5182(14)00204-2, 2014. 
• Hubertus K, Mischnik M, Timmer J, Herterich S, Mark R, Moulard M, Walter U, Geiger J. Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors. European Journal of Pharmacology. 740C:15-27, 2014. 
• de Witt SM, Swieringa F, Cavill R, ... Jurk K ... Heemskerk JW, Cosemans JM. Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature Communications. 5:4257, 2014.
• Herder C, Nuotio ML, Shah S, Blankenberg S, ..., Wild PS, ... Kumari M, Perola M, Salomaa V. Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes.  pii: DB_140731, 2014.
• Knorr M, Hausding M, Pfeffer A, Jurk K, Jansen T, Schwierczek K, Oelze M, Kröller-Schön S, Schulz E, Wenzel P, Gori T, Burgin K, Sartor D, Scherhag A, Münzel T, Daiber A. In vitro and in vivo Characterization of a New Organic Nitrate Hybrid Drug Covalently Bound to Pioglitazone. Pharmacology. 93(5-6):203-215, 2014. 
• Oelze M, Kröller-Schön S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Münzel T, Daiber A. Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging. Hypertension. 63(2):390-6, 2014.
• Prüfer S, Weber M, Stein P, Bosmann M, Stassen M, Kreft A, Schild H, Radsak MP. Oxidative burst and neutrophil elastase contribute to clearance of Aspergillus fumigatus pneumonia in mice. Immunobiology. 219:87-96, 2014.
• Ostad MA, Wild PS, Schnorbus B, Schulz A, Munzel T, Warnholtz A. Predictive value of brachial reactive hyperemia and flow-mediated dilation in stable coronary artery disease. Clinical Hemorheology and Microcirculation. 56(3):247-57, 2014.
• Bollmann F, Wu Z, Oelze M, Siuda D, Xia N, Henke J, Daiber A, Li H, Stumpo DJ, Blackshear PJ, Kleinert H, Pautz A. Endothelial Dysfunction in Tristetraprolin-deficient Mice Is Not Caused by Enhanced Tumor Necrosis Factor-α Expression. The Journal of Biological Chemistry. Vol. 289, No. 22, pp. 15653–15665, 2014.
• Schnorbus B, Daiber A, Jurk K, Warnke S, König J, Krahn U, Lackner K, Munzel T, Gori T. Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patients undergoing coronary artery stenting for an acute coronary syndrome. A randomised, prospective, controlled study. BMJ open. 4(5):e005268, 2014. 
• von Krogh AS, Kremer Hovinga JA, Tjønnfjord GE, Ringen IM, Lämmle B, Waage A, Quist-Paulsen P. The impact of congenital thrombotic thrombocytopenic purpura on pregnancy complications. Thrombosis and Haemostasis. 111(6):1180-3, 2014.
• Ponto K, Schuppan D, Zwiener I, Binder H, Mirshahi A, Diana T, Pitz S, Pfeiffer N, Kahaly G. Thyroid-associated orbitopathy is linked to gastrointestinal autoimmunity. Clinical and experimental immunology. 2014.
• Beutel ME, Wiltink J, Kirschner Y, Sinning C, Espinola-Klein C, Wild PS, Munzel T, Blettner M, Zwiener I, Lackner K, Michal M. History of depression but not current depression is associated with signs of atherosclerosis: data from the Gutenberg Health Study. Psychological Medicine. 44(5):919-25, 2014. 
• Prochaska JH, Coldewey M, Göbel S, Keller K, Hendelmeier M, Konstantinides S, Münzel T, Wild PS; for the thrombEVAL Study Group. Evaluation of oral anticoagulation therapy: rationale and design of the thrombEVAL study programme. European journal of preventive cardiology. 2014.
• Bova C, Sanchez O, Prandoni P, Lankeit M, Konstantinides S, Vanni S, Jiménez D. Identification of intermediate-risk patients with acute symptomatic pulmonary embolism. European Respiratory Journal. 2014.
• Meyer G, Vicaut E, ... Lankeit M, ... Torbicki A, Verschuren F, and Konstantinides SV for the PEITHO Investigators. Fibrinolysis for Patients with Acute Intermediate-Risk Pulmonary Embolism. New England Journal of Medicine. 370:1402-11, 2014. 
• Dellas C, Tschepe M, Seeber V, Zwiener I, Kuhnert K, Schäfer K, Hasenfuß G, Konstantinides S, Lankeit M. A novel H-FABP assay and a fast prognostic score for risk assessment of normotensive pulmonary embolism. Thrombosis Haemostasis. 111(5):996-1003, 2014. 
• Navdaev A, Subramanian H, Petunin A, Clemetson KJ, Gambaryan S, Walter U. Echicetin Coated Polystyrene Beads: A Novel Tool to Investigate GPIb-Specific Platelet Activation and Aggregation. PLOS One. 9(4):e93569, 2014.
• Jiang Y, McIntosh JJ, Reese JA, Deford CC, Kremer Hovinga JA, Lämmle B, Terrell DR, Vesely SK, Knudtson EJ, George JN. Pregnancy outcomes following recovery from acquired thrombotic thrombocytopenic purpura. Blood 123(11):1674-80, 2014. 
• Lankeit M, Jiménez D, Kostrubiec M, Dellas C, Kuhnert K, Hasenfuß G, Pruszczyk P, Konstantinides S. Validation of N-terminal pro-brain natriuretic peptide cut-off values for risk stratification of pulmonary embolism. European Respiratory Journal. 43(6):1669-77, 2014.
• Jiménez D, Kopecna D, Tapson V, Briese B, Schreiber D, Lobo JL, Monreal M, Aujesky D, Sanchez O, Meyer G, Konstantinides S, Yusen RD. Derivation and validation of multimarker prognostication for normotensive patients with acute symptomatic pulmonary embolism. American Journal of Respiratory and Critical Care Medicine. 189(6):718-26, 2014. 
• Bosmann M, Strobl B, Kichler N, Rigler D, Grailer JJ, Pache F, Murray PJ, Müller M, Ward PA. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27. Journal of Leukocyte Biology. 96(1):123-31, 2014.
• Sinning C, Keller T, Zeller T, Ojeda F, Schlüter M, Schnabel R, Lubos E, Bickel C, Lackner KJ, Diemert P, Munzel T, Blankenberg S, Wild PS. Association of high-sensitivity assayed troponin I with cardiovascular phenotypes in the general population: the population-based Gutenberg health study. Clinical Research in Cardiology. 103(3):211-22, 2014.
• Anaraki P, Patecki M, Larmann J, Tkachuk S, Jurk K, Haller H, Theilmeier G, Dumler I. Urokinase Receptor Mediates Osteogenic Differentiation of Mesenchymal Stem Cells and Vascular Calcification via the Complement C5a Receptor. Stem Cells and Development. 15;23(4):352-62, 2014. 
• Brandt M, Schönfelder T, Schwenk M, Becker C, Jäckel S, Reinhardt C, Stark K, Massberg S, Münzel T, von Brühl ML, Wenzel P. Deep vein thrombus formation induced by flow reduction in mice is determined by venous side branches. Clinical Hemorheology and Microcirculation. 56(2):145-52, 2014. 
• Beck F, Geiger J, Gambaryan S, Veit J, Vaudel M, Nollau P, Kohlbacher O, Martens L, Walter U, Sickmann A, Zahedi RP. Time-resolved characterization of camp/pka-dependant signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways. Blood. 123(5):e1-e10, 2014. 
• Kröller-Schön S, Steven S, Kossmann S, Scholz A, Daub S, Oelze M, Xia N, Hausding M, Mikhed Y, Zinßius E, Mader M, Stamm P, Treiber N, Scharffetter-Kochanek K, Li H, Schulz E, Wenzel P, Münzel T, Daiber A. Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species-Studies in White Blood Cells and in Animal Models. Antioxidants & Redox Signaling. 20(2):247-66, 2014. 
• Zwiener I, Frisch B, Binder H. Transforming RNA-Seq Data to Improve the Performance. PLOS ONE.  9(1): e85150, 2014. 
• Rocanin-Arjo A, Cohen W, ... Wild PS, ... Trégouët DA, Morange PE. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 123(5):777-85, 2014.
• Prüfer S, Weber M, Sasca D, Teschner D, Wölfel C, Stein P, Stassen M, Schild H, Radsak MP. Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells. Journal Innate Immunology. 6(3): 339-352, 2014. 
• Jimenez-Alcazar M, Napirei M, Panda R, Kohler EC, Kremer-Hovinga JA, Mannherz HG, Peine S, Renne T, Lämmle B, Fuchs TA. Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies. Journal of thrombosis and haemostasis, 13: 732-42. 2014.
• Stroka D, Keogh A, Vu D, Fort A, Stoffel MH, Kuhni-Boghenbor K, Furer C, Banz V, Demarmels Biasiutti F, Lämmle B, Candinas D, Neerman-Arbez M. In vitro rescue of FGA deletion by lentiviral transduction of an afibrinogenemic patient's hepatocytes. Journal of thrombosis and haemostasis, 12: 1874-9. 2014.