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CTH verbundene Autoren sind in Kursivschrift

Originalartikel 2024

Zeid S, Buch G, Velmeden D, Söhne J, Schulz A, Schuch A, Tröbs SO, Heidorn MW, Müller F, Strauch K, Coboeken K, Lackner KJ, Gori T, Münzel T, Prochaska JH, Wild PS. Heart rate variability: reference values and role for clinical profile and mortality in individuals with heart failure. Clin Res Cardiol. 2024 Sep;113(9):1317-1330.

Hobohm L, Paschke LM, Farmakis IT, Barco S, Partovi S, Münzel T, Konstantinides S, Keller K, Below M. Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: data from a practice-based longitudinal cohort. J Thromb Haemost. 2024 Aug;22(8):2203-2210.

Keller K, Schmitt VH, Hahad O, Espinola-Klein C, Münzel T, Lurz P, Konstantinides S, Hobohm L. Categorization of Patients With Pulmonary Embolism by Charlson Comorbidity Index. Am J Med. 2024 Aug;137(8):727-735.

Strohm L, Daiber A, Ubbens H, Krishnankutty R, Oelze M, Kuntic M, Hahad O, Klein V, Hoefer IE, von Kriegsheim A, Kleinert H, Atzler D, Lurz P, Weber C, Wild PS, Münzel T, Knosalla C, Lutgens E, Daub S. Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies. Basic Res Cardiol. 2024 Aug;119(4):1-18.

Rondeau LE, Da Luz BB, Santiago A, Bermudez-Brito M, Hann A, De Palma G, Jury J, Wang X, Verdu EF, Galipeau HJ, Rolland C, Deraison C, Ruf W, Bercik P, Vergnolle N, Caminero A. Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2. Gut Microbes. 2024 Jan-Dec;16(1):2387857.

Reinwarth AC, Wicke FS, Rückert KK, Schattenberg JM, Tüscher O, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Beutel ME. Change of self-rated physical health predicts mortality in aging individuals: results of a population-based cohort study. Arch Public Health. 2024 Aug 23;82(1):130.

Graafen D, Bart W, Halfmann MC, Müller L, Hobohm L, Yang Y, Neufang A, Espinola-Klein C, Pitton MB, Kloeckner R, Varga-Szemes A, Emrich T. In vitro and in vivo optimized reconstruction for low-keV virtual monoenergetic photon-counting detector CT angiography of lower legs. Eur Radiol Exp. 2024 Aug 1;8(1):89

Schönmehl R, Mendelsohn DH, Winter L, Pabel S, Niedermair T, Evert K, Cheung WH, Wong RMY, Schmitt VH, Keller K, Barsch F, Dietl A, Gummert JF, Schramm R, Sossalla S, Brochhausen C. Comparative Analysis of Mitochondria Surrounding the Intercalated Discs in Heart Diseases-An Ultrastructural Pilot Study. Int J Mol Sci. 2024 Jul 12;25(14):7644.

Stortecky S, Barco S, Windecker S, Heg D, Kadner A, Englberger L, Kucher N. Ultrasound-assisted catheter-directed thrombolysis versus surgical pulmonary embolectomy for intermediate-high or high-risk pulmonary embolism: a randomized phase II non-inferiority trial. Eur J Cardiothorac Surg. 2024 Jul 1;66(1):ezae252.

Cimini LA, Luijten D, Barco S, Ghanima W, Jervan Ø, Kahn SR, Konstantinides S, Lachant D, Nakano Y, Ninaber M, van Es J, van Mens T, Vonk Noordegraaf A, Becattini C, Klok FA. Pulmonary perfusion defects or residual vascular obstruction and persistent symptoms after pulmonary embolism: a systematic review and meta-analysis. ERJ Open Res. 2024 Jul 29;10(4):01010-2023.

Massey RJ, Chen Y, Panova-Noeva M, Mattheus M, Siddiqui MK, Schloot NC, Ceriello A, Pearson ER, Dawed AY. BMI variability and cardiovascular outcomes within clinical trial and real-world environments in type 2 diabetes: an IMI2 SOPHIA study. Cardiovasc Diabetol. 2024 Jul 16;23(1):256.

Keller K, Schmitt VH, Brochhausen C, Hahad O, Engelhardt M, Espinola-Klein C, Münzel T, Lurz P, Konstantinides S, Hobohm L. Sarcopenia influences usage of reperfusion treatment in patients with pulmonary embolism aged 75 years and older. Int J Cardiol Heart Vasc. 2024 Jul 19;53:101470.

Blessing R, Keller K, Dimitriadis Z, Münzel T, Gori T, Hobohm L. Temporal trends of case-fatality in patients undergoing dual-injection coronary chronic total occlusion recanalization. Clin Res Cardiol. 2024 Jul;113(7):987-994.

Wolf S, Schievano E, Amidei CB, Kucher N, Valerio L, Barco S, Fedeli U. Mortality trend of ischemic heart disease (2008-2022): A retrospective analysis of epidemiological data. Int J Cardiol. 2024 Jul 1;406:132042.


Knopp T, Jung R, Wild J, Bochenek ML, Efentakis P, Lehmann A, Bieler T, Garlapati V, Richter C, Molitor M, Perius K, Finger S, Lagrange J, Ghasemi I, Zifkos K, Kommoss KS, Masri J, Reißig S, Randriamboavonjy V, Wunderlich T, Hövelmeyer N, Weber ANR, Mufazalov IA, Bosmann M, Bechmann I, Fleming I, Oelze M, Daiber A, Münzel T, Schäfer K, Wenzel P, Waisman A, Karbach S. Myeloid cell-derived interleukin-6 induces vascular dysfunction and vascular and systemic inflammation. Eur Heart J Open. 2024 Jun 12;4(4):oeae046.

Mohr K, Keeling B, Kaier K, Neusius T, Rosovsky RP, Moriarty JM, Rosenfield K, Abele C, Farmakis IT, Keller K, Barco S, Channick RN, Giri JS, Lookstein RA, Todoran TM, Christodoulou KC, Hobohm L, Lanno M, Reed J, Binder H, Konstantinides SV, Valerio L, Secemsky EA. Modelling costs of interventional pulmonary embolism treatment: implications of US trends for a European healthcare system. Eur Heart J Acute Cardiovasc Care. 2024 Jun 30;13(6):501-505.

Panova-Noeva M, Koeck T, Schoelch C, Schulz A, Prochaska JH, Michal M, Strauch K, Schuster AK, Lackner KJ, Münzel T, Hennige AM, Wild PS. Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study. Obesity (Silver Spring). 2024 Jun;32(6):1198-1209.

Subramaniam S, Kenney D, Jayaraman A, O'Connell AK, Walachowski S, Montanaro P, Reinhardt C, Colucci G, Crossland NA, Douam F, Bosmann M. Aging is associated with an insufficient early inflammatory response of lung endothelial cells in SARS-CoV-2 infection. Front Immunol. 2024 Jun 7;15:1397990.

Fieß A, Gißler S, Wild PS, Lackner KJ, Münzel T, Michal M, Urschitz MS, Pfeiffer N, Schuster AK. Hypertensive Retinopathy is Not Associated with Low or High Birth Weight - Results from the Population-Based German Gutenberg Health Study. Clin Ophthalmol. 2024 Jun 22;18:1797-1800.

Buch G, Schulz A, Schmidtmann I, Strauch K, Wild PS. Sparse Group Penalties for bi-level variable selection. Biom J. 2024 Jun;66(4):e2200334.

Hartmann A, Grabitz SD, Wagner FM, Wild PS, Müller-Nurasyid M, Lackner KJ, Beutel ME, Münzel T, Tüscher O, Schattenberg JM, Pfeiffer N, Schuster AK. Bi-Gaussian analysis reveals distinct education-related alterations in spherical equivalent and axial length-results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol. 2024 Jun;262(6):1819-1828.

Zifkos K, Bochenek ML, Gogiraju R, Robert S, Pedrosa D, Kiouptsi K, Moiko K, Wagner M, Mahfoud F, Poncelet P, Münzel T, Ruf W, Reinhardt C, Panicot-Dubois L, Dubois C, Schäfer K. Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation. Circ Res. 2024 May 10;134(10):e93-e111.

Doundoulakis I, Farmakis IT, Theodoridis X, Konstantelos A, Christoglou M, Kotzakioulafi E, Chrysoula L, Siargkas A, Karligkiotis A, Kyprianou G, Mastromanoli E, Soulaidopoulos S, Zafeiropoulos S, Antza C, Tsiachris D, Chourdakis M. Effects of dietary interventions on cardiovascular outcomes: a network meta-analysis. Nutr Rev. 2024 May 10;82(6):715-725.

Ward C, Curry N, El-Ekiaby M, Jurk K, Versteeg HH, Keragala C, Burstyn-Cohen T, Antoniak S, Suzuki Y, Baker RI, Christophe O, Revel-Vilk S, Hart A, Deppermann C, Tran H, Pozzi N, Kahr WHA, Grover SP, Wenzel P, Brown AC, Oury C, Shea SM, Fredenburgh J, Passam FH, Winearls J, Moore HB, Tole S, Merriman E, Barnes GD, Liu ZL, Sholzberg M. Illustrated State-of-the-Art Capsules of the ISTH 2024 Congress. Res Pract Thromb Haemost. 2024 May 3;8(4):102432.

Keller K, Schmitt VH, Hahad O, Hobohm L. Outcome of Pulmonary Embolism with and without Ischemic Stroke. J Clin Med. 2024 May 7;13(10):2730.

Göbel S, Braun AS, Hahad O, von Henning U, Brandt M, Keller K, Gaida MM, Gori T, Schultheiss HP, Escher F, Münzel T, Wenzel P. Etiologies and predictors of mortality in an all-comer population of patients with non-ischemic heart failure. Clin Res Cardiol. 2024 May;113(5):737-749.


O'Brien K, Hackenberg B, Döge J, Bohnert A, Rader T, Lackner KJ, Beutel ME, Münzel T, Wild PS, Chalabi J, Schuster AK, Schmidtmann I, Matthias C, Bahr-Hamm K. Age standardization and time-of-day performance for the Oldenburg Sentence Test (OLSA): results from the population-based Gutenberg Health Study. Eur Arch Otorhinolaryngol. 2024 May;281(5):2341-2351.

Zafeiropoulos S, Farmakis IT, Milioglou I, Doundoulakis I, Gorodeski EZ, Konstantinides SV, Cooper L, Zanos S, Stavrakis S, Giamouzis G, Butler J, Giannakoulas G. Pharmacological Treatments in Heart Failure With Mildly Reduced and Preserved Ejection Fraction: Systematic Review and Network Meta-Analysis. JACC Heart Fail. 2024 Apr;12(4):616-627.

Willems RAL, Konings J, Huskens D, Middelveld H, Pepels-Aarts N, Verbeet L, de Groot PG, Heemskerk JWM, Ten Cate H, de Vos-Geelen J, de Laat B, Roest M. Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer. J Thromb Haemost. 2024 Apr;22(4):1132-1144.


Sagoschen I, Scibior B, Farmakis IT, Keller K, Graafen D, Griemert EV, Vosseler M, Treede H, Münzel T, Knorr M, Gori T, Konstantinides S, Hobohm L. A multidisciplinary pulmonary embolism response team (PERT): first experience from a single center in Germany. Clin Res Cardiol. 2024 Apr;113(4):581-590.


Kespohl M, Goetzke CC, Althof N, Bredow C, Kelm N, Pinkert S, Bukur T, Bukur V, Grunz K, Kaur D, Heuser A, Mülleder M, Sauter M, Klingel K, Weiler H, Berndt N, Gaida MM, Ruf W, Beling A. TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice. Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):843-865.


Keppeler K, Pesi A, Lange S, Helmstädter J, Strohm L, Ubbens H, Kuntić M, Kuntić I, Mihaliková D, Vujačić-Mirski K, Rosenberger A, Küster L, Frank C, Oelze M, Finger S, Zakrzewska A, Verdu E, Wild J, Karbach S, Wenzel P, Wild P, Leistner D, Münzel T, Daiber A, Schuppan D, Steven S. Vascular dysfunction and arterial hypertension in experimental celiac disease are mediated by gut-derived inflammation and oxidative stress. Redox Biol. 2024 Apr;70:103071.


Kopp S, Windschmitt J, Schnauder L, Münzel T, Keller K, Karbach S, Hobohm L, Lurz P, Sagoschen I, Wild J. Injection Site Matters: A Comparative Analysis of Transpulmonary Thermodilution via Simultaneous Femoral and Jugular Indicator Injections under Veno-Venous Extracorporeal Membrane Oxygenation Therapy. J Clin Med. 2024 Apr 17;13(8):2334.

Barco S, Wolf S. Acute pulmonary embolism: the vulnerable scores. Pol Arch Intern Med. 2024 Apr 26;134(4):16742.

Pagkalidou E, Doundoulakis I, Apostolidou-Kiouti F, Bougioukas KI, Papadopoulos K, Tsapas A, Farmakis IT, Antonopoulos AS, Giannakoulas G, Haidich AB. An overview of systematic reviews on imaging tests for diagnosis of pulmonary embolism applying different network meta-analytic methods. Hellenic J Cardiol. 2024 Mar-Apr;76:88-98.


Zelaya H, Grunz K, Nguyen TS, Habibi A, Witzler C, Reyda S, Gonzalez-Menendez I, Quintanilla-Martinez L, Bosmann M, Weiler H, Ruf W. Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling. Blood. 2024 Mar 7;143(10):845-857.

Sterling KM, Goldhaber SZ, Sharp ASP, Kucher N, Jones N, Maholic R, Meneveau N, Zlotnick D, Sayfo S, Konstantinides SV, Piazza G. Prospective Multicenter International Registry of Ultrasound-Facilitated Catheter-Directed Thrombolysis in Intermediate-High and High-Risk Pulmonary Embolism (KNOCOUT PE). Circ Cardiovasc Interv. 2024 Mar;17(3):e013448.


Müller-Calleja N, Grunz K, Nguyen TS, Posma J, Pedrosa D, Meineck M, Hollerbach A, Braun J, Muth S, Schild H, Saar K, Hübner N, Krishnaswamy S, Royce J, Teyton L, Lemmermann N, Weinmann-Menke J, Lackner KJ, Ruf W. Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development. Blood. 2024 Mar 21;143(12):1167-1180. doi: 10.1182/blood.2023022276. PMID: 38142429; PMCID: PMC10972716.


Buch G, Schulz A, Schmidtmann I, Strauch K, Wild PS. Interpretability of bi-level variable selection methods. Biom J. 2024 Mar;66(2):e2300063.

Kosmidis D, Arvanitaki A, Farmakis IT, Liakos A, Giannopoulos A, Ziakas A, Giannakoulas G. Pulmonary vasodilators and exercise in Fontan circulation: a systematic review and meta-analysis. Heart. 2024 Mar 22;110(8):552-559.


Michal M, Wiltink J, Tibubos AN, Wild PS, Münzel T, Lackner K, Pfeiffer N, König J, Gieswinkel A, Beutel M, Kerahrodi JG. Impact of depersonalization on the course of depression: longitudinal observations from the gutenberg health study. BMC Psychiatry. 2024 Mar 8;24(1):196

Hahad O, Gilan D, Michal M, Tüscher O, Chalabi J, Schuster AK, Keller K, Hobohm L, Schmitt VH, König J, Lackner KJ, Wild P, Schattenberg JM, Daiber A, Münzel T. Noise annoyance and cardiovascular disease risk: results from a 10-year follow-up study. Sci Rep. 2024 Mar 7;14(1):5619

Hobohm L, Farmakis IT, Duerschmied D, Keller K. The Current Evidence of Pulmonary Embolism Response Teams and Their Role in Future. Hamostaseologie. 2024 Mar 12.

Provenzale I, Solari FA, Schönichen C, Brouns SLN, Fernández DI, Kuijpers MJE, van der Meijden PEJ, Gibbins JM, Sickmann A, Jones C, Heemskerk JWM. Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases. FASEB J. 2024 Feb 29;38(4):e23468.

Kommoss KS, Bieler T, Ringen J, Lehmann A, Mihalceanu S, Hobohm L, Keller K, Brand A, Fischer B, Kramer D, Wild J, Waisman A, Enk A, Schäkel K, Heikenwälder M, Karbach S. A simple tool for evaluation of inflammation in psoriasis: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as markers in psoriasis patients and related murine models of psoriasis-like skin disease. J Mol Med (Berl). 2024 Feb;102(2):247-255.

Grigorean A, Lindenblatt N, Luchsinger I, Hobohm L, Konstantinides SV, Münzel T, Barco S, Keller K. Prevalence and Prognostic Role of Lymphedema in Patients with Deep Venous Thrombosis and Thrombophlebitis. Lymphat Res Biol. 2024 Feb;22(1):20-26.


De Waele L, Sakai K, Mancini I, Sinkovits G, Falter T, Inoue T, Agosti P, Rossmann H, Von Auer C, Tersteeg C, De Meyer SF, Joly BS, Veyradier A, Coppo P, Fijnheer R, Peyvandi F, Prohászka Z, Lämmle B, Vanhoorelbeke K. Open ADAMTS-13 conformation index predicts earlier relapse in immune-mediated thrombotic thrombocytopenic purpura. J Thromb Haemost. 2024 Feb;22(2):493-502.

Keller K, Göbel S, Gori T, Münzel T, Wenzel P, Hobohm L. A nationwide trend analysis on the usage of endomyocardial biopsy. Clin Cardiol. 2024 Feb;47(2):e24198.


Wicke FS, Otten D, Schulz A, Wild PS, Lackner KJ, Münzel T, König J, Ernst M, Wiltink J, Reiner I, Ghaemi Kerahrodi J, Pfeiffer N, Beutel ME. Current and past depression as risk factors for incident type 2 diabetes mellitus and pre-diabetes in men and women: evidence from a longitudinal community cohort. Diabetol Metab Syndr. 2024 Feb 1;16(1):34.


Kenneweg F, Hobohm L, Bang C, Gupta SK, Xiao K, Thum S, Ten Cate V, Rapp S, Hasenfuß G, Wild P, Konstantinides S, Wachter R, Lankeit M, Thum T. Circulating miR-let7a levels predict future diagnosis of chronic thromboembolic pulmonary hypertension. Sci Rep. 2024 Feb 24;14(1):4514.

Farmakis IT, Baroutidou A, Patsiou V, Arvanitaki A, Doundoulakis I, Hobohm L, Zafeiropoulos S, Konstantinides SV, D'Alto M, Badagliacca R, Giannakoulas G. Contribution of pressure and flow changes to resistance reduction after pulmonary arterial hypertension treatment: a meta-analysis of 3898 patients. ERJ Open Res. 2024 Jan 22;10(1):00706-2023.

Korosoglou G, Mouselimis D, Koenig E, Konstantinides S. Ultrasound-assisted catheter-directed thrombolysis in a patient with COVID-19 infection and bilateral intermediate-to-high-risk pulmonary embolism: a case report. Eur Heart J Case Rep. 2024 Jan 8;8(1):ytad628.

Last J, Herrmann E, Birschmann I, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, Zydek B, von Heymann C, Sümnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A, Lindhoff-Last E; RADOA-Registry Investigators. Clinical Course and Management of Patients with Emergency Surgery Treated with Direct Oral Anticoagulants or Vitamin K Antagonists-Results of the German Prospective RADOA-Registry. J Clin Med. 2024 Jan 3;13(1):272.

Hartmann A, Scholz I, Hoffmann EM, Strzalkowska A, Lackner KJ, Münzel T, Wicke FS, Schmidtmann I, Tüscher O, Schattenberg JM, Konstantinides S, Wild PS, Pfeiffer N, Schuster AK. Change of Intraocular Pressure Over 5 Years and its Relationship to Cardiovascular Parameters: Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci. 2024 Jan 2;65(1):12.

Hahad O, Gilan DA, Chalabi J, Al-Kindi S, Schuster AK, Wicke F, Büttner M, Tüscher O, Lackner KJ, Galle PR, Konstantinides S, Daiber A, Wild PS, Münzel T. Cumulative social disadvantage and cardiovascular disease burden and mortality. Eur J Prev Cardiol. 2024 Jan 5;31(1):40-48.

Malerba SA, Fumagalli RM, Ay C, Cesarman-Maus G, De Paula EV, Dumantepe M, Guillermo Esposito MC, Hobohm L, Sadeghipour P, Samama CM, Sartori MT, Castellucci LA, Barco S; World Thrombosis Day Steering Committee. Availability of medical and endovascular therapies for venous thromboembolism: a global survey for World Thrombosis Day. J Thromb Haemost. 2024 Jan;22(1):255-262.

Farmakis IT, Valerio L, Barco S, Christodoulou KC, Ewert R, Giannakoulas G, Held M, Hobohm L, Keller K, Wilkens H, Rosenkranz S, Konstantinides SV. Functional capacity and dyspnea during follow-up after acute pulmonary embolism. J Thromb Haemost. 2024 Jan;22(1):163-171. doi: 10.1016/j.jtha.2023.08.024. Epub 2023 Aug 29. PMID: 37652350.

Reviews 2024

Khan ES, Däinghaus T. HSP47 in human diseases: Navigating pathophysiology, diagnosis and therapy. Clin Transl Med. 2024 Aug;14(8):e1755

Talasaz AH, Sadeghipour P, Ortega-Paz L, Kakavand H, Aghakouchakzadeh M, Beavers C, Fanikos J, Eikelboom JW, Siegal DM, Monreal M, Jimenez D, Vaduganathan M, Castellucci LA, Cuker A, Barnes GD, Connors JM, Secemsky EA, Van Tassell BW, De Caterina R, Kurlander JE, Aminian A, Piazza G, Goldhaber SZ, Moores L, Middeldorp S, Kirtane AJ, Elkind MSV, Angiolillo DJ, Konstantinides S, Lip GYH, Stone GW, Cushman M, Krumholz HM, Mehran R, Bhatt DL, Bikdeli B. Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease. Nat Rev Cardiol. 2024 Aug;21(8):574-592.

Schoeppe R, Waldmann M, Jessen HJ, Renné T. An Update on Polyphosphate In Vivo Activities. Biomolecules. 2024 Aug 2;14(8):937.

Rashedi S, Greason CM, Sadeghipour P, Talasaz AH, O'Donoghue ML, Jimenez D, Monreal M, Anderson CD, Elkind MSV, Kreuziger LMB, Lang IM, Goldhaber SZ, Konstantinides SV, Piazza G, Krumholz HM, Braunwald E, Bikdeli B. Fibrinolytic Agents in Thromboembolic Diseases: Historical Perspectives and Approved Indications. Semin Thromb Hemost. 2024 Jul;50(5):773-789.

Imhof S, Hochadel M, Konstantinides S, Voigtländer T, Schmitt C, Nowak B, Rassaf T, Senges J, Münzel T, Giannitsis E, Breuckmann F. Cardiac, possible cardiac, and likely non-cardiac origin of chest pain : A hitherto underestimated parameter in German chest pain units. Herz. 2024 Jun;49(3):175-180.

Halkidis K, Lämmle B, Zheng XL. The history of thrombotic thrombocytopenic purpura research: a narrative review. Ann Blood. 2024 Jun 30;9:16. doi: 10.21037/aob-23-46.

Lämmle B, Vanhoorelbeke K, Kremer Hovinga JA, Knöbl P. 100 Years of Thrombotic Thrombocytopenic Purpura: A Story of Death and Life. Hamostaseologie. 2024 Feb;44(1):59-73.


Sørensen M, Pershagen G, Thacher JD, Lanki T, Wicki B, Röösli M, Vienneau D, Cantuaria ML, Schmidt JH, Aasvang GM, Al-Kindi S, Osborne MT, Wenzel P, Sastre J, Fleming I, Schulz R, Hahad O, Kuntic M, Zielonka J, Sies H, Grune T, Frenis K, Münzel T, Daiber A. Health position paper and redox perspectives - Disease burden by transportation noise. Redox Biol. 2024 Feb;69:102995.


Müller-Calleja N, Ruf W, Lackner KJ. Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome. Crit Rev Clin Lab Sci. 2024 Jan 31:1-18.

An O, Deppermann C. Platelet lifespan and mechanisms for clearance. Curr Opin Hematol. 2024 Jan 1;31(1):6-15.

Olie RH, Winckers K, Rocca B, Ten Cate H. Oral Anticoagulants Beyond Warfarin. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:551-575.

Editorials und Fachbeiträge 2024

Keller K, Hobohm L. Safety of early rehabilitation after acute pulmonary embolism. Eur Respir J. 2024 Sep 5;64(3):2401016.

Farmakis IT, Konstantinides SV. COVID-19 changed the world - without changing CTEPH. Eur Respir J. 2024 Aug 29;64(2):2401467.

Lämmle B. ADAMTS13 recovery in caplacizumab-treated TTP. Blood. 2024 May 2;143(18):1785-1786.

Barco S, Fumagalli RM. Pulmonary Embolism: Don't Start Me to Talkin'. Hamostaseologie. 2024 Jun;44(3):166-168.

Nilsen DWT, Kontny F, Ten Cate H. Editorial: Novel and potential biomarkers for prediction of outcome in patients with chronic and acute coronary heart disease, volume II. Front Cardiovasc Med. 2024 May 28;11:1432580.

Rommel KP, Hobohm L, Rothman AMK, Lurz P. Radiation to Illuminate the Path of Neuromodulation for Pulmonary Hypertension. JACC Basic Transl Sci. 2024 Feb 26;9(2):257-259.

Ruf W. Immune damage in Long Covid. Science. 2024 Jan 19;383(6680):262-263.

Originalartikel 2023

Coleman JR, D'Alessandro A, LaCroix I, Dzieciatkowska M, Lutz P, Mitra S, Gamboni F, Ruf W, Silliman CC, Cohen MJ. A metabolomic and proteomic analysis of pathologic hypercoagulability in traumatic brain injury patients after dura violation. J Trauma Acute Care Surg. 2023 Dec 1;95(6):925-934.

Müller FS, Aherrahrou Z, Grasshoff H, Heidorn MW, Humrich JY, Johanson L, Aherrahrou R, Reinberger T, Schulz A, Ten Cate V, Robles AP, Koeck T, Rapp S, Lange T, Brachaczek L, Luebber F, Erdmann J, Heidecke H, Schulze-Forster K, Dechend R, Lackner KJ, Pfeiffer N, Ghaemi Kerahrodi J, Tüscher O, Schwarting A, Strauch K, Münzel T, Prochaska JH, Riemekasten G, Wild PS. Autoantibodies against the chemokine receptor 3 predict cardiovascular risk. Eur Heart J. 2023 Dec 14;44(47):4935-4949.


Fischer B, Kübelbeck T, Kolb A, Ringen J, Waisman A, Wittmann M, Karbach S, Kölsch SM, Kramer D. IL-17A-driven psoriasis is critically dependent on IL-36 signaling. Front Immunol. 2023 Dec 11;14:1256133.


Morland K, Gerges C, Elwing J, Visovatti SH, Weatherald J, Gillmeyer KR, Sahay S, Mathai SC, Boucly A, Williams PG, Harikrishnan S, Minty EP, Hobohm L, Jose A, Badagliacca R, Lau EMT, Jing ZC, Vanderpool RR, Fauvel C, Leonidas Alves J Jr, Strange G, Pulido T, Qian J, Li M, Mercurio V, Zelt JGE, Moles VM, Cirulis MM, Nikkho SM, Benza RL, Elliott CG. Real-world evidence to advance knowledge in pulmonary hypertension: Status, challenges, and opportunities. A consensus statement from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative's Real-world Evidence Working Group. Pulm Circ. 2023 Dec 21;13(4):e12317.


Morland K, Gerges C, Elwing J, Visovatti SH, Weatherald J, Gillmeyer KR, Sahay S, Mathai SC, Boucly A, Williams PG, Harikrishnan S, Minty EP, Hobohm L, Jose A, Badagliacca R, Lau EMT, Jing ZC, Vanderpool RR, Fauvel C, Leonidas Alves J Jr, Strange G, Pulido T, Qian J, Li M, Mercurio V, Zelt JGE, Moles VM, Cirulis MM, Nikkho SM, Benza RL, Elliott CG. Real-world evidence to advance knowledge in pulmonary hypertension: Status, challenges, and opportunities. A consensus statement from the Pulmonary Vascular Research Institute's Innovative Drug Development Initiative's Real-world Evidence Working Group. Pulm Circ. 2023 Dec 21;13(4):e12317.

Marx-Gross S, Fieß A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Much higher prevalence of keratoconus than announced results of the Gutenberg Health Study (GHS). Graefes Arch Clin Exp Ophthalmol. 2023 Nov;261(11):3241-3247.


Häuser F, Rossmann H, Adenaeuer A, Shrestha A, Marandiuc D, Paret C, Faber J, Lackner KJ, Lämmle B, Beck O. Hereditary Spherocytosis: Can Next-Generation Sequencing of the Five Most Frequently Affected Genes Replace Time-Consuming Functional Investigations? Int J Mol Sci. 2023 Nov 30;24(23):17021.


Reinwarth AC, Wicke FS, Hettich N, Ernst M, Otten D, Brähler E, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Beutel ME. Self-rated physical health predicts mortality in aging persons beyond objective health risks. Sci Rep. 2023 Nov 9;13(1):19531.

Popal Z, Nickel KF, Wöltje M, Aibibu D, Knipfer C, Smeets R, Renné T. Polyphosphate-loaded silk fibroin membrane as hemostatic agent in oral surgery: a pilot study. Int J Implant Dent. 2023 Nov 17;9(1):44.


Farmakis IT, Barco S, Giannakoulas G, Keller K, Valerio L, Tichelbäcker T, Partovi S, Ahrens I, Konstantinides SV, Hobohm L. A nationwide analysis of reperfusion therapies for pulmonary embolism in older patients with frailty. EuroIntervention. 2023 Nov 17;19(9):772-781.


Baroutidou A, Arvanitaki A, Farmakis IT, Patsiou V, Giannopoulos A, Efthimiadis G, Ziakas A, Giannakoulas G. Transcatheter closure of atrial septal defect in the elderly: a systematic review and meta-analysis. Heart. 2023 Nov 10;109(23):1741-1750.

Hahad O, Schmidt FP, Hübner J, Foos P, Al-Kindi S, Schmitt VH, Hobohm L, Keller K, Große-Dresselhaus C, Schmeißer J, Koppe-Schmeißer F, Vosseler M, Gilan D, Schulz A, Chalabi J, Wild PS, Daiber A, Herzog J, Münzel T. Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance-results from a pooled analysis of human field studies. Clin Res Cardiol. 2023 Nov;112(11):1690-1698.



Fumagalli RM, Schürch K, Grigorean A, Holy EW, Münger M, Pleming W, Kucher N, Barco S. Clinical outcomes of a balloon-expandable stent for symptomatic obstructions of the subclavian or innominate arteries. Vasa. 2023 Nov;52(6):409-415.

Hackenberg B, O'Brien K, Döge J, Lackner KJ, Beutel ME, Münzel T, Wild PS, Pfeiffer N, Chalabi J, Matthias C, Bahr-Hamm K. Vertigo and its burden of disease-Results from a population-based cohort study. Laryngoscope Investig Otolaryngol. 2023 Oct 23;8(6):1624-1630.

Chalikias G, Tsigalou C, Stakos D, Kakoudakis E, Thomaidis A, Kipouros G, Panopoulou M, Xanthopoulou AM, Lantzouraki A, Konstantinides S, Tziakas D. Coronary Artery Ectasia as an Autoimmune Disease Paradigm in a Cross-Sectional Case-Control Study. Am J Cardiol. 2023 Oct 15;205:63-68.


Riehl DR, Sharma A, Roewe J, Murke F, Ruppert C, Eming SA, Bopp T, Kleinert H, Radsak MP, Colucci G, Subramaniam S, Reinhardt C, Giebel B, Prinz I, Guenther A, Strand D, Gunzer M, Waisman A, Ward PA, Ruf W, Schäfer K, Bosmann M. Externalized histones fuel pulmonary fibrosis via a platelet-macrophage circuit of TGFβ1 and IL-27. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2215421120.

Velollari O, Reinhardt CM, Knorr M, Schnitzler K, Graafen D, Miederer M, von Bardeleben RS, Münzel T, Schmidt KH, Giebels C, Schäfers HJ, Hobohm L. Late-Onset Prosthetic Endocarditis with Paraaortic Abscess Caused by Cutibacterium acnes. Infect Dis Rep. 2023 Oct 18;15(5):635-641.


Barco S, Virdone S, Götschi A, Ageno W, Arcelus JI, Bingisser R, Colucci G, Cools F, Duerschmied D, Gibbs H, Fumagalli RM, Gerber B, Haas S, Himmelreich JCL, Hobbs R, Hobohm L, Jacobson B, Kayani G, Lopes RD, MacCallum P, Micieli E, Righini M, Robert-Ebadi H, Rocha AT, Rosemann T, Sawhney J, Schellong S, Sebastian T, Spirk D, Stortecky S, Turpie AGG, Voci D, Kucher N, Pieper K, Held U, Kakkar AK; OVID and ETHIC Investigators. Enoxaparin for symptomatic COVID-19 managed in the ambulatory setting: An individual patient level analysis of the OVID and ETHIC trials. Thromb Res. 2023 Oct;230:27-32.


Bochenek ML, Saar K, Nazari-Jahantigh M, Gogiraju R, Wiedenroth CB, Münzel T, Mayer E, Fink L, Schober A, Hübner N, Guth S, Konstantinides S, Schäfer K. Endothelial Overexpression of TGF-β-Induced Protein Impairs Venous Thrombus Resolution: Possible Role in CTEPH. JACC Basic Transl Sci. 2023 Oct 25;9(1):100-116.

Mavromanoli AC, Barco S, Ageno W, Bouvaist H, Brodmann M, Cuccia C, Couturaud F, Dellas C, Dimopoulos K, Duerschmied D, Empen K, Faggiano P, Ferrari E, Galiè N, Galvani M, Ghuysen A, Giannakoulas G, Huisman MV, Jiménez D, Kozak M, Lang IM, Meneveau N, Münzel T, Palazzini M, Petris AO, Piovaccari G, Salvi A, Schellong S, Schmidt KH, Verschuren F, Schmidtmann I, Toenges G, Klok FA, Konstantinides SV; PEITHO-2 Investigators. Recovery of right ventricular function after intermediate-risk pulmonary embolism: results from the multicentre Pulmonary Embolism International Trial (PEITHO)-2. Clin Res Cardiol. 2023 Oct;112(10):1372-1381.


Blessing R, Drosos I, Molitor M, Münzel T, Wenzel P, Gori T, Dimitriadis Z. Evaluation of right-ventricular function by two-dimensional echocardiography and two-dimensional speckle-tracking echocardiography in patients with successful RCA CTO recanalization. Clin Res Cardiol. 2023 Oct;112(10):1454-1462.

Göbel S, Wingerter A, Prochaska JH, Schulz A, Neu MA, Henninger N, Spix C, Beutel M, Lackner K, Münzel T, Lam CS, Merzenich H, Faber J, Wild PS. Development and Phenotype of Heart Failure in Long-Term Survivors of Childhood Cancer: The CVSS Study. J Am Heart Assoc. 2023 Oct 3;12(19):e030020.


Korb CA, Lackner KJ, Wolters D, Schuster AK, Nickels S, Beutgen VM, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Pfeiffer N, Grus FH. Association of autoantibody levels with different stages of age-related macular degeneration (AMD): Results from the population-based Gutenberg Health Study (GHS). Graefes Arch Clin Exp Ophthalmol. 2023 Oct;261(10):2763-2773.


Fumagalli RM, Gloor E, Kaufmann PA, Frehner M, Voci D, Konstantinides SV, Kucher N, Nicoletti TF, Pecci A, Valerio L, Barco S. Common laboratory tests and their correlation with the clinical presentation and prognosis of Lemierre syndrome. Anaerobe. 2023 Oct;83:102773.

Baidildinova G, Pallares Robles A, Ten Cate V, Kremers BMM, Heitmeier S, Ten Cate H, Mees BME, Spronk HMH, Wild PS, Ten Cate-Hoek AJ, Jurk K. Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease. Thromb Res. 2023 Oct;230:105-118.


Ten Cate V, Rapp S, Schulz A, Pallares Robles A, Jurk K, Koeck T, Espinola-Klein C, Halank M, Seyfarth HJ, Beutel ME, Schuster AK, Marini F, Hobohm L, Lankeit M, Lackner KJ, Ruf W, Münzel T, Andrade-Navarro MA, Prochaska JH, Konstantinides SV, Wild PS. Circulating microRNAs predict recurrence and death following venous thromboembolism. J Thromb Haemost. 2023 Oct;21(10):2797-2810.

Zuin M, Piazza G, Barco S, Bikdeli B, Hobohm L, Giannakoulas G, Konstantinides S. Time-based reperfusion in haemodynamically unstable pulmonary embolism patients: does early reperfusion therapy improve survival? Eur Heart J Acute Cardiovasc Care. 2023 Oct 25;12(10):714-720.

Global Cardiovascular Risk Consortium; Magnussen C, Ojeda FM, Leong DP, Alegre-Diaz J, Amouyel P, Aviles-Santa L, De Bacquer D, Ballantyne CM, Bernabé-Ortiz A, Bobak M, Brenner H, Carrillo-Larco RM, de Lemos J, Dobson A, Dörr M, Donfrancesco C, Drygas W, Dullaart RP, Engström G, Ferrario MM, Ferrières J, de Gaetano G, Goldbourt U, Gonzalez C, Grassi G, Hodge AM, Hveem K, Iacoviello L, Ikram MK, Irazola V, Jobe M, Jousilahti P, Kaleebu P, Kavousi M, Kee F, Khalili D, Koenig W, Kontsevaya A, Kuulasmaa K, Lackner KJ, Leistner DM, Lind L, Linneberg A, Lorenz T, Lyngbakken MN, Malekzadeh R, Malyutina S, Mathiesen EB, Melander O, Metspalu A, Miranda JJ, Moitry M, Mugisha J, Nalini M, Nambi V, Ninomiya T, Oppermann K, d'Orsi E, Pająk A, Palmieri L, Panagiotakos D, Perianayagam A, Peters A, Poustchi H, Prentice AM, Prescott E, Risérus U, Salomaa V, Sans S, Sakata S, Schöttker B, Schutte AE, Sepanlou SG, Sharma SK, Shaw JE, Simons LA, Söderberg S, Tamosiunas A, Thorand B, Tunstall-Pedoe H, Twerenbold R, Vanuzzo D, Veronesi G, Waibel J, Wannamethee SG, Watanabe M, Wild PS, Yao Y, Zeng Y, Ziegler A, Blankenberg S. Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality. N Engl J Med. 2023 Oct 5;389(14):1273-1285.

Krug J, Bochenek ML, Gogiraju R, Laubert-Reh D, Lackner KJ, Münzel T, Wild PS, Espinola-Klein C, Schäfer K. Circulating Soluble EPCR Levels Are Reduced in Patients with Ischemic Peripheral Artery Disease and Associated with Markers of Endothelial and Vascular Function. Biomedicines. 2023 Sep 4;11(9):2459.


Falter T, Rossmann H, de Waele L, Dekimpe C, von Auer C, Müller-Calleja N, Häuser F, Degreif A, Marandiuc D, Messmer X, Sprinzl M, Lackner KJ, Jurk K, Vanhoorelbeke K, Lämmle B. A novel von Willebrand factor multimer ratio as marker of disease activity in thrombotic thrombocytopenic purpura. Blood Adv. 2023 Sep 12;7(17):5091-5102.


Nikorowitsch J, Bei der Kellen R, Haack A, Magnussen C, Prochaska J, Wild PS, Dörr M, Twerenbold R, Schnabel RB, Kirchhof P, Blankenberg S, Markus MRP, Wenzel JP. Correlation of systolic and diastolic blood pressure with echocardiographic phenotypes of cardiac structure and function from three German population-based studies. Sci Rep. 2023 Sep 4;13(1):14525.


Schönichen C, Montague SJ, Brouns SLN, Burston JJ, Cosemans JMEM, Jurk K, Kehrel BE, Koenen RR, Ní Áinle F, O'Donnell VB, Soehnlein O, Watson SP, Kuijpers MJE, Heemskerk JWM, Nagy M. Antagonistic Roles of Human Platelet Integrin αIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow. Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):1700-1712.

Chu G, Valerio L, Barco S, Huisman MV, Konstantinides SV, Klok FA. External validation of AF-BLEED for predicting major bleeding and for tailoring NOAC dose in AF patients: A post hoc analysis in the ENGAGE AF-TIMI 48. Thromb Res. 2023 Sep;229:225-231.


Karwen T, Kolczynska-Matysiak K, Gross C, Löffler MC, Friedrich M, Loza-Valdes A, Schmitz W, Wit M, Dziaczkowski F, Belykh A, Trujillo-Viera J, El-Merahbi R, Deppermann C, Nawaz S, Hastoy B, Demczuk A, Erk M, Wieckowski MR, Rorsman P, Heinze KG, Stegner D, Nieswandt B, Sumara G. Platelet-derived lipids promote insulin secretion of pancreatic β cells. EMBO Mol Med. 2023 Sep 11;15(9):e16858.

Kumar S, Yoon S, Milioglou I, Tashtish N, Farmakis I, Dallan LAP, Mogalapalli A, Arruda M, Filby SJ. Left Atrial Appendage Closure Outcomes in Patients With Cancer at a Single Tertiary Center. Am J Cardiol. 2023 Sep 1;202:176-181.


Jiménez D, Tapson V, Yusen RD, Becattini C, Moores L, Barnes GD, Monreal M, Konstantinides S, Bikdeli B. Revised Paradigm for Acute Pulmonary Embolism Prognostication and Treatment. Am J Respir Crit Care Med. 2023 Sep 1;208(5):524-527.


Iding AFJ, Kremers BMM, Pallares Robles A, Ten Cate H, Ten Cate-Hoek AJ. Residual Venous Obstruction as an Indicator of Clinical Outcomes following Deep Vein Thrombosis: A Management Study. Thromb Haemost. 2023 Aug;123(8):763-772.


Goedegebuur J, Abbel D, Accassat S, Achterberg WP, Akbari A, Arfuch VM, Baddeley E, Bax JJ, Becker D, Bergmeijer B, Bertoletti L, Blom JW, Calvetti A, Cannegieter SC, Castro L, Chavannes NH, Coma-Auli N, Couffignal C, Edwards A, Edwards M, Enggaard H, Font C, Gava A, Geersing GJ, Geijteman ECT, Greenley S, Gregory C, Gussekloo J, Hoffmann I, Højen AA, van den Hout WB, Huisman MV, Jacobsen S, Jagosh J, Johnson MJ, Jørgensen L, Juffermans CCM, Kempers EK, Konstantinides S, Kroder AF, Kruip MJHA, Lafaie L, Langendoen JW, Larsen TB, Lifford K, van der Linden YM, Mahé I, Maiorana L, Maraveyas A, Martens ESL, Mayeur D, van Mens TE, Mohr K, Mooijaart SP, Murtagh FEM, Nelson A, Nielsen PB, Ording AG, Ørskov M, Pearson M, Poenou G, Portielje JEA, Raczkiewicz D, Rasmussen K, Trinks-Roerdink E, Schippers I, Seddon K, Sexton K, Sivell S, Skjøth F, Søgaard M, Szmit S, Trompet S, Vassal P, Visser C, van Vliet LM, Wilson E, Klok FA, Noble SIR. Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. Thromb Res. 2023 Aug;228:54-60

Kowalewski C, Schnürer P, Kopp S, Windschmitt J, Oezkur M, Kriege M, Münzel T, Kaes J, Sagoschen I, Wild J. VV-ECMO as bridge and safety net for successful therapeutic polypragmasy in a case of influenza-triggered near-fatal asthma. Clin Case Rep. 2023 Aug 10;11(8):e7709.

Hess CN, Hsia J, Carroll IA, Nehler MR, Ruf W, Morrow DA, Nicolau JC, Berwanger O, Szarek M, Capell WH, Johri S, Pursley MS, Gupta R, Meehan PS, Franchi F, Effron MB, Marshall D, Graybill CA, Huebler SP, Keuer T, Bristow MR, Bonaca MP. Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1572-1582.

Beutel T, Koestner C, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Nübling M, Becker J, Letzel S. Burnout, self-rated general health and life satisfaction among teachers and other academic occupational groups. Front Public Health. 2023 Aug 11;11:1209995.


Schaller T, Ringen J, Fischer B, Bieler T, Perius K, Knopp T, Kommoss KS, Korn T, Heikenwälder M, Oelze M, Daiber A, Münzel T, Kramer D, Wenzel P, Wild J, Karbach S, Waisman A. Reactive oxygen species produced by myeloid cells in psoriasis as a potential biofactor contributing to the development of vascular inflammation. Biofactors. 2023 Jul-Aug;49(4):861-874.


Luijten D, Talerico R, Barco S, Cannegieter SC, Delcroix M, Ende-Verhaar YM, Huisman MV, Konstantinidis S, Mairuhu ATA, van Mens TE, Ninaber M, Pruszczyk P, Vonk Noordegraaf A, Klok FA. Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: an updated systematic review and meta-analysis. Eur Respir J. 2023 Jul 7;62(1):2300449.

Schmitt VH, Hobohm L, Sagoschen I, Sivanathan V, Hahad O, Espinola-Klein C, Münzel T, Keller K. Diabetes Mellitus and Its Association with Adverse In-Hospital Outcomes in Patients with COVID-19-A Nationwide Study. Viruses. 2023 Jul 26;15(8):1627.


Pontarollo G, Kollar B, Mann A, Khuu MP, Kiouptsi K, Bayer F, Brandão I, Zinina VV, Hahlbrock J, Malinarich F, Mimmler M, Bhushan S, Marini F, Ruf W, Belheouane M, Baines JF, Endres K, Reba SM, Raker VK, Deppermann C, Welsch C, Bosmann M, Soshnikova N, Chassaing B, Bergentall M, Sommer F, Bäckhed F, Reinhardt C. Commensal bacteria weaken the intestinal barrier by suppressing epithelial neuropilin-1 and Hedgehog signaling. Nat Metab. 2023 Jul;5(7):1174-1187.

Pallares Robles A, Ten Cate V, Lenz M, Schulz A, Prochaska JH, Rapp S, Koeck T, Leineweber K, Heitmeier S, Opitz CF, Held M, Espinola-Klein C, Lackner KJ, Münzel T, Konstantinides SV, Ten Cate-Hoek A, Ten Cate H, Wild PS. Unsupervised clustering of venous thromboembolism patients by clinical features at presentation identifies novel endotypes that improve prognostic stratification. Thromb Res. 2023 Jul;227:71-81

Ernst M, Hinz A, Brähler E, Merzenich H, Faber J, Wild PS, Beutel ME. Quality of life after pediatric cancer: comparison of long-term childhood cancer survivors' quality of life with a representative general population sample and associations with physical health and risk indicators. Health Qual Life Outcomes. 2023 Jul 4;21(1):65

Werner AM, Ernst M, Brähler E, Tibubos AN, Otten D, Reiner I, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Beutel ME. The association of depressive symptoms and body weight change in midlife - Results from the Gutenberg Health Study in Germany. J Affect Disord. 2023 Jul 1;332:115-124

Moos S, Regen T, Wanke F, Tian Y, Arendholz LT, Hauptmann J, Heinen AP, Bleul L, Bier K, El Malki K, Reinhardt C, Prinz I, Diefenbach A, Wolz C, Schittek B, Waisman A, Kurschus FC. IL-17 Signaling in Keratinocytes Orchestrates the Defense against Staphylococcus aureus Skin Infection. J Invest Dermatol. 2023 Jul;143(7):1257-1267.e10.


Prochaska JH, Jünger C, Schulz A, Arnold N, Müller F, Heidorn MW, Baumkötter R, Zahn D, Koeck T, Tröbs SO, Lackner KJ, Daiber A, Binder H, Shah SJ, Gori T, Münzel T, Wild PS. Effects of empagliflozin on left ventricular diastolic function in addition to usual care in individuals with type 2 diabetes mellitus-results from the randomized, double-blind, placebo-controlled EmDia trial. Clin Res Cardiol. 2023 Jul;112(7):911-922.

Hoffmann J, Hanß S, Kraus M, Schaller J, Schäfer C, Stahl D, Anker SD, Anton G, Bahls T, Blankenberg S, Blumentritt A, Boldt LH, Cordes S, Desch S, Doehner W, Dörr M, Edelmann F, Eitel I, Endres M, Engelhardt S, Erdmann J, Eulenburg K, Falk V, Felix SB, Frank D, Franke T, Frey N, Friede T, Geidel L, Germans L, Grabmaier U, Halle M, Hausleiter J, Jakobi V, Jebran AF, Jobs A, Kääb S, Karakas M, Katus HA, Klatt A, Knosalla C, Krebser J, Landmesser U, Lee M, Lehnert K, Lesser S, Leyh K, Lorbeer R, Mach-Kolb S, Meder B, Nagel E, Nolte CH, Parwani AS, Petersmann A, Puls M, Rau H, Reiser M, Rienhoff O, Scharfe T, Schattschneider M, Scheel H, Schnabel RB, Schuster A, Schmitt B, Seidler T, Seiffert M, Stähli BE, Stas A, J Stocker T, von Stülpnagel L, Thiele H, Wachter R, Wakili R, Weis T, Weitmann K, Wichmann HE, Wild P, Zeller T, Hoffmann W, Zeisberg EM, Zimmermann WH, Krefting D, Kühne T, Peters A, Hasenfuß G, Massberg S, Sommer T, Dimmeler S, Eschenhagen T, Nauck M. The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Clin Res Cardiol. 2023 Jul;112(7):923-941.


Nagy M*, Robles AP*, Visser M, Koeck T, Ten Cate V, Ten Cate-Hoek AJ, Schwers S, Heitmeier S, Ten Cate H, Wild PS, Spronk HMH. Predictive value for increased activated factor XI activity in acute venous thromboembolism. J Thromb Haemost. 2023 Jun;21(6):1610-1622.

Eckelt J, Hobohm L, Merten MC, Pagel CF, Eggers AS, Lerchbaumer MH, Stangl K, Hasenfuß G, Konstantinides S, Schmidtmann I, Lankeit M, Ebner M. Long-term mortality in patients with pulmonary embolism: results in a single-center registry. Res Pract Thromb Haemost. 2023 Jun 14;7(5):100280.


Molitor M, Bayo-Jimenez MT, Hahad O, Witzler C, Finger S, Garlapati VS, Rajlic S, Knopp T, Bieler TK, Aluia M, Wild J, Lagrange J, Blessing R, Rapp S, Schulz A, Kleinert H, Karbach S, Steven S, Ruf W, Wild P, Daiber A, Münzel T, Wenzel P. Aircraft noise exposure induces pro-inflammatory vascular conditioning and amplifies vascular dysfunction and impairment of cardiac function after myocardial infarction. Cardiovasc Res. 2023 Jun 13;119(6):1416-1426

Keller K, Kohring C, Farmakis IT, Valerio L, Barco S, Bätzing J, Akmatov MK, Konstantinides S, Münzel T, Hobohm L, Holstiege J. Impact of venous thromboembolism on incidence of arterial thromboembolism - An analysis of German outpatient claims data. Thromb Res. 2023 Jun;226:9-17

Nagy M, Robles AP, Visser M, Koeck T, Ten Cate V, Ten Cate-Hoek AJ, Schwers S, Heitmeier S, Ten Cate H, Wild PS, Spronk HMH. Predictive value for increased activated factor XI activity in acute venous thromboembolism. J Thromb Haemost. 2023 Jun;21(6):1610-1622

Hartmann A, Grabitz SD, Hoffmann EM, Wild PS, Schmidtmann I, Lackner KJ, Beutel ME, Münzel T, Tüscher O, Schattenberg JM, Pfeiffer N, Schuster AK. Intraocular Pressure and Its Relation to Climate Parameters-Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci. 2023 Jun 1;64(7):15

Wittig J, Drekolia MK, Kyselova A, Delgado Lagos F, Bochenek ML, Hu J, Schäfer K, Fleming I, Bibli SI. Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation. Redox Biol. 2023 Jun;62:102694.

Farmakis IT, Valerio L, Barco S, Alsheimer E, Ewert R, Giannakoulas G, Hobohm L, Keller K, Mavromanoli AC, Rosenkranz S, Morris TA, Konstantinides SV, Held M, Dumitrescu D. Cardiopulmonary exercise testing during follow-up after acute pulmonary embolism. Eur Respir J. 2023 Jun 8;61(6):2300059

Leidecker M, Bertling A, Hussain M, Bischoff M, Eble JA, Fender AC, Jurk K, Rumpf C, Herrmann M, Kehrel BE, Niemann S. Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells. Microbiol Spectr. 2023 Jun 15;11(3):e0388622

Mora D, Mateo J, Nieto JA, Bikdeli B, Yamashita Y, Barco S, Jimenez D, Demelo-Rodriguez P, Rosa V, Yoo HHB, Sadeghipour P, Monreal M; Registro Informatizado de Enfermedad TromboEmbólica (RIETE) Investigators. Machine learning to predict major bleeding during anticoagulation for venous thromboembolism: possibilities and limitations. Br J Haematol. 2023 Jun;201(5):971-981

Bikdeli B, Lo YC, Khairani CD, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky EA, Klok FA, Hunsaker AR, Aghayev A, Muriel A, Wang Y, Hussain MA, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber SZ, Zhou L, Monreal M, Krumholz HM, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study. Thromb Haemost. 2023 Jun;123(6):649-662

Kroone C, Tieken C, Kocatürk B, Paauwe M, Blok EJ, Ünlü B, van den Berg YW, Stanganello E, Kapteijn MY, Swier N, Zhang X, Duits DEM, Lin Y, Oostenbrink LVE, van den Akker RFP, Mosnier LO, Hawinkels LJ, van Vlijmen BJM, Ruf W, Kuppen PJ, Cannegieter SC, Buijs JT, Versteeg HH. Tumor-expressed factor VII is associated with survival and regulates tumor progression in breast cancer. Blood Adv. 2023 Jun 13;7(11):2388-2400

Krenzlin V, Schöche J, Walachowski S, Reinhardt C, Radsak MP, Bosmann M. Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates. Eur J Immunol. 2023 May;53(5):e2250339

Englert H, Göbel J, Khong D, Omidi M, Wolska N, Konrath S, Frye M, Mailer RK, Beerens M, Gerwers JC, Preston RJS, Odeberg J, Butler LM, Maas C, Stavrou EX, Fuchs TA, Renné T. Targeting NETs using dual-active DNase1 variants. Front Immunol. 2023 May 23;14:1181761

Keller K, Haghi SHR, Hahad O, Schmidtmann I, Chowdhury S, Lelieveld J, Münzel T, Hobohm L. Air pollution impacts on in-hospital case-fatality rate of ischemic stroke patients. Thromb Res. 2023 May;225:116-125

Hettich-Damm N, Petersen J, Zahn D, Baumkoetter R, Wild PS, Muenzel T, Schuster AK, Koenig J, Lackner K, Pfeiffer N, Beutel ME, Engwicht E. Gender Differences and the Impact of Partnership and Children on Quality of Life During the COVID-19 Pandemic. Int J Public Health. 2023 May 22;68:1605826

Zbinden S, Voci D, Grigorean A, Holy EW, Kaufmann PA, Münger M, Pleming W, Kucher N, Barco S. Clinical outcomes of ultrasound-assisted coagulation monitoring-adjusted catheter-directed thrombolysis for acute pulmonary embolism. Thromb Res. 2023 May;225:73-78

Gogiraju R, Witzler C, Shahneh F, Hubert A, Renner L, Bochenek ML, Zifkos K, Becker C, Thati M, Schäfer K. Deletion of endothelial leptin receptors in mice promotes diet-induced obesity. Sci Rep. 2023 May 22;13(1):8276

Klok FA, Pruszczyk P, Konstantinides SV. Thrombolytic treatment of life-threatening pulmonary embolism in times of alteplase shortage. Eur Heart J. 2023 May 21;44(20):1837-1839

Zhang P, Solari FA, Heemskerk JWM, Kuijpers MJE, Sickmann A, Walter U, Jurk K. Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. Int J Mol Sci. 2023 Apr 24;24(9):7776

Beck S, Öftering P, Li R, Hemmen K, Nagy M, Wang Y, Zarpellon A, Schuhmann MK, Stoll G, Ruggeri ZM, Heinze KG, Heemskerk JWM, Ruf W, Stegner D, Nieswandt B. Platelet glycoprotein V spatio-temporally controls fibrin formation. Nat Cardiovasc Res. 2023 Apr;2(4):368-382

Barco S, Mavromanoli AC, Kreitner KF, Bunck AC, Gertz RJ, Ley S, Valerio L, Klok FA, Gerhardt F, Rosenkranz S, Konstantinides SV. Preexisting Chronic Thromboembolic Pulmonary Hypertension in Acute Pulmonary Embolism. Chest. 2023 Apr;163(4):923-932

Farmakis IT, Valerio L, Giannakoulas G, Hobohm L, Cushman M, Piazza G, Konstantinides SV, Barco S. Social determinants of health in pulmonary embolism management and outcome in hospitals: Insights from the United States nationwide inpatient sample. Res Pract Thromb Haemost. 2023 Apr 6;7(3):100147

Zuin M, Barco S, Giannakoulas G, Engelen MM, Hobohm L, Valerio L, Vandenbriele C, Verhamme P, Vanassche T, Konstantinides SV. Risk of venous thromboembolic events after COVID-19 infection: a systematic review and meta-analysis. J Thromb Thrombolysis. 2023 Apr;55(3):490-498

Hackenberg B, O'Brien K, Döge J, Lackner KJ, Beutel ME, Münzel T, Pfeiffer N, Schulz A, Schmidtmann I, Wild PS, Matthias C, Bahr-Hamm K. Tinnitus Prevalence in the Adult Population-Results from the Gutenberg Health Study. Medicina (Kaunas). 2023 Mar 20;59(3):620

Chen DY, Chin CV, Kenney D, Tavares AH, Khan N, Conway HL, Liu G, Choudhary MC, Gertje HP, O'Connell AK, Adams S, Kotton DN, Herrmann A, Ensser A, Connor JH, Bosmann M, Li JZ, Gack MU, Baker SC, Kirchdoerfer RN, Kataria Y, Crossland NA, Douam F, Saeed M. Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA.1 attenuation. Nature. 2023 Mar;615(7950):143-150

Voci D, Fedeli U, Valerio L, Schievano E, Righini M, Kucher N, Spirk D, Barco S. Mortality rate related to peripheral arterial disease: A retrospective analysis of epidemiological data (years 2008-2019). Nutr Metab Cardiovasc Dis. 2023 Mar;33(3):516-522

Keller K, Sagoschen I, Konstantinides S, Gori T, Münzel T, Hobohm L. Incidence and risk factors of myocarditis in hospitalized patients with COVID-19. J Med Virol. 2023 Mar;95(3):e28646.


Garlapati V, Molitor M, Michna T, Harms GS, Finger S, Jung R, Lagrange J, Efentakis P, Wild J, Knorr M, Karbach S, Wild S, Vujacic-Mirski K, Münzel T, Daiber A, Brandt M, Gori T, Milting H, Tenzer S, Ruf W, Wenzel P. Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1-driven fibrotic remodeling in ischemic heart failure. J Clin Invest. 2023 Feb 15;133(4):e156436

Kopp S, Tilch MK, Sagoschen I, Kaes J, Kuniss M, Neumann T, Yang Y, Schnitzler K, Schmidt KH, Rostock T, Münzel T, Konstantinides S, Wild J, Hobohm L. A rare case of right heart failure with the necessity for veno-arterial extracorporeal membrane oxygenation following pulmonary vein stenosis after radiofrequency ablation for atrial fibrillation. Pulm Circ. 2023 Feb 21;13(1):e12189

Adenaeuer A, Barco S, Trinchero A, Krutmann S, Nazir HF, Ambaglio C, Rocco V, Pancione Y, Tomao L, Ruiz-Sáez A, Echenagucia M, Alesci S, Sollfrank S, Ezigbo ED, Häuser F, Lackner KJ, Lämmle B, Rossmann H. Severe high-molecular-weight kininogen deficiency: clinical characteristics, deficiency-causing KNG1 variants, and estimated prevalence. J Thromb Haemost. 2023 Feb;21(2):237-254

Keller K, Farmakis IT, Valerio L, Koelmel S, Wild J, Barco S, Schmidt FP, Espinola-Klein C, Konstantinides S, Münzel T, Sagoschen I, Hobohm L. Predisposing factors for admission to intensive care units of patients with COVID-19 infection-Results of the German nationwide inpatient sample. Front Public Health. 2023 Feb 15;11:1113793

Keller K, Schmitt VH, Sagoschen I, Münzel T, Espinola-Klein C, Hobohm L. CRB-65 for Risk Stratification and Prediction of Prognosis in Pulmonary Embolism. J Clin Med. 2023 Feb 5;12(4):1264

Blessing R, Drosos I, Münzel T, Wenzel P, Gori T, Dimitriadis Z. Evaluation of right atrial function by two-dimensional echocardiography and strain imaging in patients with RCA CTO recanalization. BMC Cardiovasc Disord. 2023 Feb 12;23(1):85

Hackenberg B, Döge J, O'Brien K, Bohnert A, Lackner KJ, Beutel ME, Michal M, Münzel T, Wild PS, Pfeiffer N, Schulz A, Schmidtmann I, Matthias C, Bahr K. Tinnitus and Its Relation to Depression, Anxiety, and Stress-A Population-Based Cohort Study. J Clin Med. 2023 Feb 1;12(3):1169

Hahad O, Schmitt VH, Arnold N, Keller K, Prochaska JH, Wild PS, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Schattenberg JM, Tüscher O, Daiber A, Münzel T. Chronic cigarette smoking is associated with increased arterial stiffness in men and women: evidence from a large population-based cohort. Clin Res Cardiol. 2023 Feb;112(2):270-284

Keller K, Schmitt VH, Ostad MA, Münzel T, Hobohm L, Espinola-Klein C. Mansoor's Self-Report Tool for Cardiovascular Risk Assessment predicts adverse in-hospital events in patients with pulmonary embolism. Clin Respir J. 2023 Feb;17(2):80-89

Santiago A, Hann A, Constante M, Rahmani S, Libertucci J, Jackson K, Rueda G, Rossi L, Rithwick R, Ruf W, Schertzer J, Caminero A, Bercik P, Galipeau HJ, Verdu EF. Crohn's disease proteolytic microbiota enhances inflammation through PAR2 pathway in gnotobiotic mice. Gut Microbes. 2023 Jan-Dec;15(1):2205425

Araldi E, Jutzeler CR, Ristow M. Lithium treatment extends human lifespan: findings from the UK Biobank. Aging (Albany NY). 2023 Jan 11;15(2):421-440

Hobohm L, Sagoschen I, Barco S, Farmakis IT, Fedeli U, Koelmel S, Gori T, Espinola-Klein C, Münzel T, Konstantinides S, Keller K. COVID-19 infection and its impact on case fatality in patients with pulmonary embolism. Eur Respir J. 2023 Jan 27;61(1):2200619

Iding AFJ, Kremers BMM, Nagy M, Pallares Robles A, Ten Cate H, Spronk HMH, Ten Cate-Hoek AJ. Translational insights into mechanisms underlying residual venous obstruction and the role of factor XI, P-selectin and GPVI in recurrent venous thromboembolism. Thromb Res. 2023 Jan;221:58-64

Ernst M, Werner AM, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. Posttraumatic growth after childhood cancer: Psychometric evaluation of a five-item short form and associations with mental health. J Psychosom Res. 2023 Jan;164:111099

Farmakis IT, Barco S, Hobohm L, Braekkan SK, Connors JM, Giannakoulas G, Hunt BJ, Keller K, Mavromanoli AC, Trinchero A, Konstantinides SV, Valerio L. Maternal mortality related to pulmonary embolism in the United States, 2003-2020. Am J Obstet Gynecol MFM. 2023 Jan;5(1):100754

Stingl JV, Ban SA, Nagler M, Schmidtmann I, Wild PS, Lackner KJ, Münzel T, Beutel ME, Pfeiffer N, Schuster AK. Five-year change in refractive error and its risk factors: results from the Gutenberg Health Study. Br J Ophthalmol. 2023 Jan;107(1):140-146

Rosenkranz S, Pausch C, Coghlan JG, Huscher D, Pittrow D, Grünig E, Staehler G, Vizza CD, Gall H, Distler O, Delcroix M, Ghofrani HA, Ewert R, Kabitz HJ, Skowasch D, Behr J, Milger K, Halank M, Wilkens H, Seyfarth HJ, Held M, Scelsi L, Neurohr C, Vonk-Noordegraaf A, Ulrich S, Klose H, Claussen M, Eisenmann S, Schmidt KH, Remppis BA, Skride A, Jureviciene E, Gumbiene L, Miliauskas S, Löffler-Ragg J, Lange TJ, Olsson KM, Hoeper MM, Opitz C. Risk stratification and response to therapy in patients with pulmonary arterial hypertension and comorbidities: A COMPERA analysis. J Heart Lung Transplant. 2023 Jan;42(1):102-114

Reviews 2023

Casari M, Siegl D, Deppermann C, Schuppan D. Macrophages and platelets in liver fibrosis and hepatocellular carcinoma. Front Immunol. 2023 Dec 5;14:1277808.

Anyaegbunam UA, More P, Fontaine JF, Cate VT, Bauer K, Distler U, Araldi E, Bindila L, Wild P, Andrade-Navarro MA. A Systematic Review of Lipid-Focused Cardiovascular Disease Research: Trends and Opportunities. Curr Issues Mol Biol. 2023 Dec 9;45(12):9904-9916.


Boey JJE, Dhundi U, Ling RR, Chiew JK, Fong NC, Chen Y, Hobohm L, Nair P, Lorusso R, MacLaren G, Ramanathan K. Extracorporeal Membrane Oxygenation for Pulmonary Embolism: A Systematic Review and Meta-Analysis. J Clin Med. 2023 Dec 22;13(1):64.

Dremova O, Mimmler M, Paeslack N, Khuu MP, Gao Z, Bosmann M, Garo LP, Schön N, Mechler A, Beneich Y, Rebling V, Mann A, Pontarollo G, Kiouptsi K, Reinhardt C. Sterility testing of germ-free mouse colonies. Front Immunol. 2023 Nov 7;14:1275109.


Valerio L, Baddour LM. Septic Pulmonary Embolism: A Contemporary Profile. Semin Thromb Hemost. 2023 Nov;49(8):840-847.

Guth S, Wilkens H, Halank M, Held M, Hobohm L, Konstantinides S, Omlor A, Seyfarth HJ, Schäfers HJ, Mayer E, Wiedenroth CB. Chronisch thromboembolische pulmonale Hypertonie (Gruppe 4) [Chronic thromboembolic pulmonary hypertension]. Pneumologie. 2023 Nov;77(11):937-946. German.


Kiouptsi K, Casari M, Mandel J, Gao Z, Deppermann C. Intravital Imaging of Thrombosis Models in Mice. Hamostaseologie. 2023 Oct;43(5):348-359.


Götzinger F, Lauder L, Sharp ASP, Lang IM, Rosenkranz S, Konstantinides S, Edelman ER, Böhm M, Jaber W, Mahfoud F. Interventional therapies for pulmonary embolism. Nat Rev Cardiol. 2023 Oct;20(10):670-684.


Huang WC, Mailer RK, Renné T. In-vivo functions and regulation of polyphosphate in the vascular system. Curr Opin Hematol. 2023 Sep 1;30(5):159-166.

Kiouptsi K, Pontarollo G, Reinhardt C. Gut Microbiota and the Microvasculature. Cold Spring Harb Perspect Med. 2023 Aug 1;13(8):a041179.



Kommoss KS, Enk A, Heikenwälder M, Waisman A, Karbach S, Wild J. Cardiovascular comorbidity in psoriasis - psoriatic inflammation is more than just skin deep. J Dtsch Dermatol Ges. 2023 Jul;21(7):718-725.


Danckwardt S, Trégouët DA, Castoldi E. Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders. Cardiovasc Res. 2023 Jul 6;119(8):1624-1640. doi: 10.1093/cvr/cvad046. Erratum in: Cardiovasc Res. 2023 Jun 16.


Ten Cate V, Prochaska JH, Schulz A, Nagler M, Robles AP, Jurk K, Koeck T, Rapp S, Düber C, Münzel T, Konstantinides SV, Wild PS. Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis. EClinicalMedicine. 2023 Apr 27;59:101973

Hobohm L, Keller K, Konstantinides S. Lungenembolie [Pulmonary embolism]. Z Herz Thorax Gefasschir. 2023;37(3-4):133-142. German.




Krolevets M, Cate VT, Prochaska JH, Schulz A, Rapp S, Tenzer S, Andrade-Navarro MA, Horvath S, Niehrs C, Wild PS. DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Clin Epigenetics. 2023 Mar 30;15(1):56

Buch G, Schulz A, Schmidtmann I, Strauch K, Wild PS. A systematic review and evaluation of statistical methods for group variable selection. Stat Med. 2023 Feb 10;42(3):331-352

Farmakis IT, Keller K, Barco S, Konstantinides SV, Hobohm L. From acute pulmonary embolism to post-pulmonary embolism sequelae. Vasa. 2023 Jan;52(1):29-37

Farmakis IT, Giannakoulas G. Management of COVID-19 in Patients with Pulmonary Arterial Hypertension. Heart Fail Clin. 2023 Jan;19(1):107-114

Mamilos A, Winter L, Schmitt VH, Barsch F, Grevenstein D, Wagner W, Babel M, Keller K, Schmitt C, Gürtler F, Schreml S, Niedermair T, Rupp M, Alt V, Brochhausen C. Macrophages: From Simple Phagocyte to an Integrative Regulatory Cell for Inflammation and Tissue Regeneration-A Review of the Literature. Cells. 2023 Jan 11;12(2):276

Hobohm L, Keller K, Konstantinides S. Lungenembolie [Pulmonary embolism]. Inn Med (Heidelb). 2023 Jan;64(1):40-49. German. doi: 10.1007/s00108-022-01460-3.

Editorials und Fachbeiträge 2023

Konstantinides SV. Kidney Disease and Cancer Risk in Patients with Venous Thromboembolism: What Does It Mean for Clinical Practice? Thromb Haemost. 2023 Dec;123(12):1177-1179.

Mavromanoli AC, Jiménez D, Sanchez O, Sobkowicz B, Vanni S, Kurzyna M, Becattini C, Pruszczyk P, Wilkens H, Bova C, Tschöpe C, Sawicka-Śmiarowska E, Grifoni C, Kostrubiec M, Torbicki A, Meneveau N, Kresoja KP, Konstantinides SV. Major in-hospital bleeding in patients with pulmonary embolism treated with systemic thrombolysis. Thromb Res. 2023 Nov;231:29-31.

Gül D, Krämer OH, Reinhardt C. Starving out brain tumors: a reprogrammed lysine catabolism serves as a novel target for glioblastoma treatment. Signal Transduct Target Ther. 2023 Oct 9;8(1):401.


Reinhardt C, Rühl H. Animal and Cellular Models in Thrombosis and Hemostasis. Hamostaseologie. 2023 Oct;43(5):319-320.


Nourse J, Danckwardt S. MicroRNAs as prognostic biomarkers for (cancer-associated) venous thromboembolism?". J Thromb Haemost. 2023 Sep;21(9):2634-2637.

Akbulut AC, Arisz RA, Baaten CCFMJ, Baidildinova G, Barakzie A, Bauersachs R, Ten Berg J, van den Broek WWA, de Boer HC, Bonifay A, Bröker V, Buka RJ, Ten Cate H, Ten Cate-Hoek AJ, Cointe S, De Luca C, De Simone I, Diaz RV, Dignat-George F, Freson K, Gazzaniga G, van Gorp ECM, Habibi A, Henskens YMC, Iding AFJ, Khan A, Koenderink GH, Konkoth A, Lacroix R, Lahiri T, Lam W, Lamerton RE, Lorusso R, Luo Q, Maas C, McCarty OJT, van der Meijden PEJ, Meijers JCM, Mohapatra AK, Nevo N, Robles AP, Poncelet P, Reinhardt C, Ruf W, Saraswat R, Schönichen C, Schutgens R, Simioni P, Spada S, Spronk HMH, Tazhibayeva K, Thachil J, Diaz RV, Vallier L, Veninga A, Verhamme P, Visser C, Watson SP, Wenzel P, Willems RAL, Willers A, Zhang P, Zifkos K, van Zonneveld AJ. Blood Coagulation and Beyond: Position Paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thromb Haemost. 2023 Aug;123(8):808-839.



Pontarollo G, Reinhardt C. The hemorrhage risk of dasatinib therapy. Blood. 2023 Jun 15;141(24):2917-2918.

Lämmle B. Mechanisms of ADAMTS13 inhibition in iTTP. Blood. 2023 Jun 15;141(24):2919-2920.


Subramaniam S, Reinhardt C, Kulkarni PP, Spiezia L. Editorial: COVID-19 and thrombo-inflammatory responses. Front Cardiovasc Med. 2023 Jun 15;10:1231909

Ghanem A, Andrassy M, Duerschmied D, Fuernau G, Geisler T, Hennersdorf M, Knorr M, Lange TJ, Masri-Zada A, Michels G, Rosenkranz S, Schulze PC, Tichelbaecker T, Tiefenbacher C, Wilkens H, Konstantinides S. Interventional treatment and multidisciplinary management strategies for acute pulmonary embolism. KARDIOLOGIE. 2023; 17(3): 141-159

Whyte CS, Panova-Noeva M. Editorial: Women in thrombosis. Front Cardiovasc Med. 2023 Feb 21;10:1159938

Originalartikel 2022

Méan M, Breakey N, Stalder O, Alberio L, Limacher A, Angelillo-Scherrer A, Fontana P, Beer HJ, Rodondi N, Aujesky D, Lämmle B, Escher R. Thrombophilia and outcomes of venous thromboembolism in older patients. Res Pract Thromb Haemost. 2022 Dec 16;7(1):100015

Haase T, Müller C, Stoffers B, Kirn P, Waldenberger M, Kaiser FJ, Karakas M, Kim SV, Voss S, Wild PS, Lackner KJ, Andersson J, Söderberg S, Lindner D, Zeller T. G Protein-Coupled Receptor 15 Expression Is Associated with Myocardial Infarction. Int J Mol Sci. 2022 Dec 22;24(1):180

Veras FP, Publio GA, Melo BM, Prado DS, Norbiato T, Cecilio NT, Hiroki C, Damasceno LEA, Jung R, Toller-Kawahisa JE, Martins TV, Assunção SF, Lima D, Alves MG, Vieira GV, Tavares LA, Alves-Rezende ALR, Karbach SH, Nakaya HI, Cunha TM, Souza CS, Cunha FQ, Sales KU, Waisman A, Alves-Filho JC. Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation. Cell Rep. 2022 Dec 27;41(13):111897

Langer F, Gerlach HE, Schimke A, Heinken A, Hoffmann U, Noppeney T, Pittrow D, Klotsche J, Rabe E, Bauersachs R; INSIGHTS-SVT study group. Clinical outcomes of cancer-associated isolated superficial vein thrombosis in daily practice. Thromb Res. 2022 Dec;220:145-152

Hahad O, Beutel ME, Gilan DA, Chalabi J, Schuster AK, Gianicolo E, Lackner KJ, Lieb K, Galle PR, Wild PS, Daiber A, Münzel T. Noise annoyance and risk of prevalent and incident atrial fibrillation-A sex-specific analysis. Front Public Health. 2022 Dec 2;10:1061328

Bonaca MP, Szarek M, Debus ES, Nehler MR, Patel MR, Anand SS, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM. Efficacy and safety of rivaroxaban versus placebo after lower extremity bypass surgery: A post hoc analysis of a "CASPAR like" outcome from VOYAGER PAD. Clin Cardiol. 2022 Dec;45(12):1143-1146

Potere N, Barco S, Mahé I, Cesarman-Maus G, Angchaisuksiri P, Leader A, Okoye HC, Olayemi E, Ay C, Carrier M, Connors JM, Farmakis IT, Fumagalli RM, Jing ZC, Lee LH, McLintock C, Ní Ainle F, Giannakoulas G, Goto S, Guillermo Esposito MC, Jara-Palomares L, Szlaszynska M, Tan CW, Van Es N, Wang TF, Hunt BJ, Di Nisio M. Awareness of venous thromboembolism among patients with cancer: Preliminary findings from a global initiative for World Thrombosis Day. J Thromb Haemost. 2022 Dec;20(12):2964-2971

Sanchez O, Konstantinides SV. Response: Does Fibrinolytic Strategy of Pulmonary Embolism International ThrOmbolysis (PEITHO)-3 Trial Need More Strong Evidence? Thromb Haemost. 2022 Dec;122(12):2052-2053

Lerchbaumer MH, Aviram G, Ebner M, Ritter CO, Steimke L, Rozenbaum Z, Adam SZ, Granot Y, Hasenfuß G, Lotz J, Hamm B, Konstantinides SV, Lankeit M. Optimized definition of right ventricular dysfunction on computed tomography for risk stratification of pulmonary embolism. Eur J Radiol. 2022 Dec;157:110554

Gogiraju R, Renner L, Bochenek ML, Zifkos K, Molitor M, Danckwardt S, Wenzel P, Münzel T, Konstantinides S, Schäfer K. Arginase-1 Deletion in Erythrocytes Promotes Vascular Calcification via Enhanced GSNOR (S-Nitrosoglutathione Reductase) Expression and NO Signaling in Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2022 Dec;42(12):e291-e310.

Wenger N, Sebastian T, Beer JH, Mazzolai L, Aujesky D, Hayoz D, Engelberger RP, Korte W, Voci D, Kucher N, Barco S, Spirk D. Differences in duration of anticoagulation after pulmonary embolism and deep vein thrombosis: Findings from the SWIss Venous ThromboEmbolism Registry (SWIVTER). Thromb Res. 2022 Dec;220:65-71.

Chakrabarty S, Bui Q, Badeanlou L, Hester K, Chun J, Ruf W, Ciaraldi TP, Samad F. S1P/S1PR3 signalling axis protects against obesity-induced metabolic dysfunction. Adipocyte. 2022 Dec;11(1):69-83.

Baidildinova G, Ten Cate V, Nagler M, Panova-Noeva M, Rapp S, Köck T, Prochaska JH, Heitmeier S, Gerdes C, Schwers S, Konstantinides SV, Münzel T, Espinola-Klein C, Lackner KJ, Spronk HMN, Ten Cate H, van der Meijden PEJ, Leineweber K, Wild PS, Jurk K. Subtype-specific plasma signatures of platelet-related protein releasate in acute pulmonary embolism. Thromb Res. 2022 Dec;220:75-87.

Beckmann L, Mäder J, Voigtlaender M, Klingler F, Schulenkorf A, Lehr C, Regenhardt J, Bokemeyer C, Ruf W, Rolling C, Langer F. Inhibition of protein disulfide isomerase with PACMA-31 regulates monocyte tissue factor through transcriptional and posttranscriptional mechanisms. Thromb Res. 2022 Dec;220:48-59

Fleischer MI, Röhrig N, Raker VK, Springer J, Becker D, Ritz S, Bros M, Stege H, Haist M, Grabbe S, Haub J, Becker C, Reyda S, Disse J, Schmidt T, Mahnke K, Weiler H, Ruf W, Steinbrink K. Protease- and cell type-specific activation of protease-activated receptor 2 in cutaneous inflammation. J Thromb Haemost. 2022 Dec;20(12):2823-2836

Lindhoff-Last E, Birschmann I, Bidenharn AJ, Kuhn J, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, Lucks J, Zydek B, von Heymann C, Sümnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators. Pharmacokinetics of Phenprocoumon in Emergency Situations-Results of the Prospective Observational RADOA-Registry (Reversal Agent Use in Patients Treated with Direct Oral Anticoagulants or Vitamin K Antagonists Registry). Pharmaceuticals (Basel). 2022 Nov 19;15(11):1437

Keller K, Sivanathan V, Schmitt VH, Ostad MA, Münzel T, Espinola-Klein C, Hobohm L. Incidence and impact of venous thromboembolism in hospitalized patients with Crohn's disease. Thromb Res. 2022 Nov;219:77-85

Sagoschen I, Keller K, Wild J, Münzel T, Hobohm L. Case Fatality of Hospitalized Patients with COVID-19 Infection Suffering from Acute Respiratory Distress Syndrome in Germany. Viruses. 2022 Nov 14;14(11):2515

Albertsen IE, Konstantinides SV, Piazza G, Goldhaber SZ, Larsen TB, Søgaard M, Nielsen PB. Risk of Recurrent Venous Thromboembolism in Selected Subgroups of Men: A Danish Nationwide Cohort Study. TH Open. 2022 Nov 18;6(4):e378-e386

Keller K, Sagoschen I, Schmitt VH, Münzel T, Gori T, Hobohm L. Hypothermia and its role in patients with ST-segment-elevation myocardial infarction and cardiac arrest. Front Cardiovasc Med. 2022 Nov 29;9:1051978

Voci D, Götschi A, Held U, Bingisser R, Colucci G, Duerschmied D, Fumagalli RM, Gerber B, Hasse B, Keller DI, Konstantinides SV, Mach F, Rampini SK, Righini M, Robert-Ebadi H, Rosemann T, Roth-Zetzsche S, Sebastian T, Simon NR, Spirk D, Stortecky S, Vaisnora L, Kucher N, Barco S; OVID investigators. Enoxaparin for outpatients with COVID-19: 90-day results from the randomised, open-label, parallel-group, multinational, phase III OVID trial. Thromb Res. 2022 Nov 12:S0049-3848(22)00440-6

Konrath S, Mailer RK, Beerens M, Englert H, Frye M, Kuta P, Preston RJS, Maas C, Butler LM, Roest M, de Laat B, Renné T. Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood. Front Cardiovasc Med. 2022 Nov 28;9:1008410

Britto-Borges T, Ludt A, Boileau E, Gjerga E, Marini F, Dieterich C. Magnetique: an interactive web application to explore transcriptome signatures of heart failure. J Transl Med. 2022 Nov 7;20(1):513

Morodomi Y, Kanaji S, Sullivan BM, Zarpellon A, Orje JN, Won E, Shapiro R, Yang XL, Ruf W, Schimmel P, Ruggeri ZM, Kanaji T. Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2212659119

Hasselwander S, Xia N, Mimmler M, Ascher S, Knopp T, Reifenberg G, Karbach S, Ruf W, Reinhardt C, Li H. B lymphocyte-deficiency in mice promotes venous thrombosis. Heliyon. 2022 Nov 17;8(11):e11740

Roewe J, Walachowski S, Sharma A, Berthiaume KA, Reinhardt C, Bosmann M. Bacterial polyphosphates induce CXCL4 and synergize with complement anaphylatoxin C5a in lung injury. Front Immunol. 2022 Nov 3;13:980733. doi: 10.3389/fimmu.2022.980733

Kohls N, Konstantinides SV, Lang IM, Funk GC, Huber K. Risk stratification and risk-adapted management of acute pulmonary embolism. Wien Klin Wochenschr. 2022 Nov 7. doi: 10.1007/s00508-022-02104-0

Farmakis IT, Barco S, Mavromanoli AC, Konstantinides SV, Valerio L. Performance Status and Long-Term Outcomes in Cancer-Associated Pulmonary Embolism: Insights From the Hokusai-VTE Cancer Study. JACC CardioOncol. 2022 Nov 15;4(4):507-518.

Wicke FS, Schmidt P, Petersen J, Ernst M, Krakau L, Brähler E, Tibubos AN, Otten D, Reiner I, Michal M, Schulz A, Münzel T, Wild PS, König J, Lackner KJ, Pfeiffer N, Beutel ME. Depression predicts equivalized income five years later, but not vice versa: Results from the prospective Gutenberg Health Study. Soc Sci Med. 2022 Nov;313:115395.

Kremers BMM, Posma JN, Heitmeier S, Glunz J, Ten Cate H, Pallares Robles A, Daemen JHC, Ten Cate-Hoek AJ, Mees BME, Spronk HMH. Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease. Sci Rep. 2022 Nov 1;12(1):18388.

Ünlü B, Kocatürk B, Rondon AMR, Lewis CS, Swier N, van den Akker RFP, Krijgsman D, Noordhoek I, Blok EJ, Bogdanov VY, Ruf W, Kuppen PJK, Versteeg HH. Integrin regulation by tissue factor promotes cancer stemness and metastatic dissemination in breast cancer. Oncogene. 2022 Nov;41(48):5176-5185.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Lower levels of vWF are associated with lower risk of cardiovascular disease. Res Pract Thromb Haemost. 2022 Nov 6;6(7):e12797.

Gabelmann V, Grabs F, Diestelmeier S, Heindl F, Vosseler M, Münzel T, Sagoschen I, Wild J. Quadrivalvular nonbacterial thrombotic endocarditis in a patient with clear cell cervical cancer. Clin Case Rep. 2022 Oct 17;10(10):e6434

Willems LH, Thijssen DHJ, Groh LA, Kooijman NI, Ten Cate H, Spronk HMH, Donders ART, van der Vijver-Coppen RJ, van Hoek F, Nagy M, Reijnen MMPJ, Warlé MC. Dual pathway inhibition as compared to acetylsalicylic acid monotherapy in relation to endothelial function in peripheral artery disease, a phase IV clinical trial. Front Cardiovasc Med. 2022 Oct 6;9:979819

Baumkötter R, Yilmaz S, Zahn D, Fenzl K, Prochaska JH, Rossmann H, Schmidtmann I, Schuster AK, Beutel ME, Lackner KJ, Münzel T, Wild PS. Protective behavior and SARS-CoV-2 infection risk in the population - Results from the Gutenberg COVID-19 study. BMC Public Health. 2022 Oct 31;22(1):1993.

Pokora RM, Büttner M, Schulz A, Schuster AK, Merzenich H, Teifke A, Michal M, Lackner K, Münzel T, Zeissig SR, Wild PS, Singer S, Wollschläger D. Determinants of mammography screening participation-a cross-sectional analysis of the German population-based Gutenberg Health Study (GHS). PLoS One. 2022 Oct 5;17(10):e0275525.

Schmitt VH, Hobohm L, Vosseler M, Brochhausen C, Münzel T, Espinola-Klein C, Keller K. Temporal trends in patients with peripheral artery disease influenced by diabetes mellitus in Germany. J Diabetes. 2022 Oct;14(10):670-684

Keller K, Schmitt VH, Hobohm LMA, Brochhausen C, Münzel T, Espinola-Klein C. Temporal Trends in Patients with Peripheral Artery Disease Influenced by COVID-19 Pandemic. J Clin Med. 2022 Oct 30;11(21):6433

Pruszczyk P, Klok FA, Kucher N, Roik M, Meneveau N, Sharp ASP, Nielsen-Kudsk JE, Obradović S, Barco S, Giannini F, Stefanini G, Tarantini G, Konstantinides S, Dudek D. Percutaneous treatment options for acute pulmonary embolism: a clinical consensus statement by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function and the European Association of Percutaneous Cardiovascular Interventions. EuroIntervention. 2022 Oct 7;18(8):e623-e638

Gogiraju R, Gachkar S, Velmeden D, Bochenek ML, Zifkos K, Hubert A, Münzel T, Offermanns S, Schäfer K. Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. Thromb Haemost. 2022 Oct;122(10):1814-1826

Tarasco E, von Krogh AS, Hrdlickova R, Braschler TR, Iwaniec T, Knöbl PN, Hamada E, Pikovsky O, Farese S, Gutwein O, Kessler P, Schultz NH, von Auer C, Windyga J, Friedman K, Hrachovinova I, George JN, Matsumoto M, Schneppenheim R, Lämmle B, Kremer Hovinga JA. Hereditary thrombotic thrombocytopenic purpura and COVID-19: Impacts of vaccination and infection in this rare disease. Res Pract Thromb Haemost. 2022 Oct 21;6(7):e12814.

Khamis A, Gül D, Wandrey M, Lu Q, Knauer SK, Reinhardt C, Strieth S, Hagemann J, Stauber RH. The Vitamin D Receptor-BIM Axis Overcomes Cisplatin Resistance in Head and Neck Cancer. Cancers (Basel). 2022 Oct 19;14(20):5131

Kalmanti L, Lindhoff-Last E. Bleeding Issues in Women Under Oral Anticoagulation. Hamostaseologie. 2022 Oct;42(5):337-347

Farmakis IT, Barco S, Mavromanoli AC, Agnelli G, Cohen AT, Giannakoulas G, Mahan CE, Konstantinides SV, Valerio L. Cost-of-Illness Analysis of Long-Term Health Care Resource Use and Disease Burden in Patients With Pulmonary Embolism: Insights From the PREFER in VTE Registry. J Am Heart Assoc. 2022 Oct 18;11(20):e027514

Fedeli U, Barbiellini Amidei C, Marcon A, Casotto V, Grippo F, Grande E, Gaisl T, Barco S. Mortality Related to Chronic Obstructive Pulmonary Disease during the COVID-19 Pandemic: An Analysis of Multiple Causes of Death through Different Epidemic Waves in Veneto, Italy. Int J Environ Res Public Health. 2022 Oct 7;19(19):12844.

Kaymaz C, Akbal OY, Keskin B, Tokgoz HC, Hakgor A, Karagoz A, Tanyeri S, Kultursay B, Kulahcioglu S, Dogan C, Bayram Z, Efe SÇ, Erkılınç A, Tanboga IH, Akbulut M, Ozdemir N, Tapson V, Konstantinides S. An Eight-year, Single-center Experience on Ultrasound Assisted Thrombolysis with Moderate-dose, Slow-infusion Regimen in Pulmonary Embolism. Curr Vasc Pharmacol. 2022;20(4):370-378.

Jurk K, Adenaeuer A, Sollfrank S, Groß K, Häuser F, Czwalinna A, Erkel J, Fritsch N, Marandiuc D, Schaller M, Lackner KJ, Rossmann H, Bergmann F. Novel GATA1 Variant Causing a Bleeding Phenotype Associated with Combined Platelet α-/δ-Storage Pool Deficiency and Mild Dyserythropoiesis Modified by a SLC4A1 Variant. Cells. 2022 Sep 29;11(19):3071

Hahad O, Beutel M, Gilan DA, Michal M, Schulz A, Pfeiffer N, König J, Lackner K, Wild P, Daiber A, Münzel T. The association of smoking and smoking cessation with prevalent and incident symptoms of depression, anxiety, and sleep disturbance in the general population.https://pubmed.ncbi.nlm.nih.gov/35777492/ J Affect Disord. 2022 Sep 15;313:100-109

Bell E, Desuki A, Karbach S, Göbel S. Successful treatment of doxorubicin-induced cardiomyopathy with low-dose sacubitril/valsartan: a case report. Eur Heart J Case Rep. 2022 Sep 23;6(10):ytac396

Willems LH, Maas DPMSM, Kramers K, Reijnen MMPJ, Riksen NP, Ten Cate H, van der Vijver-Coppen RJ, de Borst GJ, Mees BME, Zeebregts CJ, Hannink G, Warlé MC. Correction to: Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs. 2022 Sep;82(13):1435.

Kiel M, Grabitz SD, Hopf S, Koeck T, Wild PS, Schmidtmann I, Lackner KJ, Münzel T, Beutel ME, Pfeiffer N, Schuster AK. Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study. J Ophthalmol. 2022 Sep 9;2022:9520512.

Keller K, Geyer M, Hobohm L, Tamm AR, Kreidel F, Ruf TF, Hell M, Schmitt VH, Bachmann K, Born S, Schulz E, Münzel T, von Bardeleben RS. Survival benefit of overweight patients undergoing MitraClip® procedure in comparison to normal-weight patients. Clin Cardiol. 2022 Sep 7

Wolf S, Spirk D, Forgo G, Sebastian T, Voci D, Kucher N, Barco S. Prevalent use of high-intensity statin therapy and LDL-C target attainment among PAD patients undergoing angioplasty. Vasa. 2022 Sep 2. doi: 10.1024/0301-1526/a001025.

Fumagalli RM, Aimasso U, Valeriani E, Mumoli N, Szlaszynska M, Antonucci E, Palareti G, Mastroiacovo D, Di Nisio M, Barco S. Quality of warfarin anticoagulation in adults with short bowel syndrome on home parenteral nutrition. Vasa. 2022 Sep;51(5):320-322.

Klok FA, Piazza G, Sharp ASP, Ní Ainle F, Jaff MR, Chauhan N, Patel B, Barco S, Goldhaber SZ, Kucher N, Lang IM, Schmidtmann I, Sterling KM, Becker D, Martin N, Rosenfield K, Konstantinides SV. Ultrasound-facilitated, catheter-directed thrombolysis vs anticoagulation alone for acute intermediate-high-risk pulmonary embolism: Rationale and design of the HI-PEITHO study. Am Heart J. 2022 Sep;251:43-53.

Fieß A, Stingl J, Urschitz MS, Hoffmann EM, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Birth weight and its association with optic nerve head morphology - results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2022 Sep;100(6):e1349-e1350

Fieß A, Marx-Groß S, Wasielica-Poslednik J, Nagler M, Schmidtmann I, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Peripheral corneal thickness and associated factors - results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2022 Sep;100(6):e1298-e1305.

Pavlaki M, Moiko K, Thomaidis A, Chalikias G, Schäfer K, Konstantinides S, Tziakas D. Modulators of Nitric Oxide-Dependent Osteoinductive Activity of Human Red Blood Cells. TH Open. 2022 Sep 12;6(3):e248-e250.

Farmakis IT, Valerio L, Bikdeli B, Connors JM, Giannakoulas G, Goldhaber SZ, Hobohm L, Hunt BJ, Keller K, Spyropoulos AC, Barco S. Annual mortality related to pulmonary embolism in the US before and during the COVID-19 pandemic. J Am Coll Cardiol. 2022 Aug 12:S0735-1097(22)06535-4.

Keller K, Hartung K, Del Castillo Carillo L, Treiber J, Stock F, Schröder C, Hugenschmidt F, Friedmann-Bette B. Exercise Hypertension in Athletes. J Clin Med. 2022 Aug 19;11(16):4870

Liu X, Wang Y, Bauer AT, Kirschfink M, Ding P, Gebhardt C, Borsig L, Tüting T, Renné T, Häffner K, Hu W, Schneider SW, Gorzelanny C. Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2122716119.

Voigtlaender M, Edler C, Gerling M, Schädler J, Ondruschka B, Schröder AS, Sperhake J, Ehrhardt S, Wang L, Haddad M, Kiencke V, Renné T, Roedl K, Kluge S, Wichmann D, Langer F. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors. Thromb Res. 2022 Aug 28;218:171-176.

Hobohm L, Sagoschen I, Barco S, Farmakis IT, Fedeli U, Koelmel S, Gori T, Espinola-Klein C, Münzel T, Konstantinides S, Keller K. COVID-19 infection and its impact on case-fatality in patients with pulmonary embolism. Eur Respir J. 2022 Aug 18:2200619.

Hu Y, Scharrer A, Hau C, Ay C, Berckmans RJ, Ruf W, Nieuwland R, Thaler J. Coagulation signaling from amniotic fluid to fetal skin. Blood Adv. 2022 Aug 16:bloodadvances.2022007971.

Kreuzpointner R, Johner F, Roth-Zetzsche S, Kucher N, Barco S. Clinical presentation and long-term follow-up of 45 patients with Mondor disease: A single-center longitudinal study. Vasc Med. 2021 Aug;26(4):409-414.

Blessing R, Buono A, Ahoopai M, Geyer M, Knorr M, Brandt M, Steven S, Drosos I, Muenzel T, Wenzel P, Gori T, Dimitriadis Z. Use of intravascular ultrasound for optimal vessel sizing in chronic total occlusion percutaneous coronary intervention. Front Cardiovasc Med. 2022 Aug 3;9:922366.

Shpakova V, Rukoyatkina N, Walter U, Gambaryan S. Potential and limitations of PKA/ PKG inhibitors for platelet studies. Platelets. 2022 Aug 18;33(6):859-868

Rashidi F, Barco S, Rezaeifar P, Sadeghipour P, Ghodrati S, Bakhshandeh H, Mousavi-Aghdas SA, Sadeghi A, Sharifi A, Valizadeh H, Mikaeili H, Rafiee F, Navarbaf Z, Farajian G, Mahmoodpoor A, Bikdeli B, Ansarin K. Tissue plasminogen activator for the treatment of adults with critical COVID-19: A pilot randomized clinical trial. Thromb Res. 2022 Aug;216:125-128.

Göbel S, Hobohm L, Desuki A, Gori T, Münzel T, Claudio R, Wenzel P, Keller K. Impact of cardiac amyloidosis on outcomes of patients hospitalized with heart failure. Eur J Intern Med. 2022 Aug;102:88-96.

Barco S, Voci D, Held U, Sebastian T, Bingisser R, Colucci G, Duerschmied D, Frenk A, Gerber B, Götschi A, Konstantinides SV, Mach F, Robert-Ebadi H, Rosemann T, Simon NR, Spechbach H, Spirk D, Stortecky S, Vaisnora L, Righini M, Kucher N; OVID investigators. Enoxaparin for primary thromboprophylaxis in symptomatic outpatients with COVID-19 (OVID): a randomised, open-label, parallel-group, multicentre, phase 3 trial. Lancet Haematol. 2022 Aug;9(8):e585-e593.

Pleming W, Barco S, Voci D, Sacco C, Zane F, Granziera S, Corsi G, Konstantinides SV, Kucher N, Pecci A, Valerio L. Cardiac and Cerebral Arterial Complications of Lemierre Syndrome: Results from a Systematic Review and Individual Patient Data Meta-analysis. Hamostaseologie. 2022 Aug;42(4):261-267.

Hogan SE, Nehler MR, Anand S, Patel MR, Debus S, Jackson MT, Buchanan C, King RW, Hess C, Muehlhofer E, Haskell LP, Bauersachs RM, Berkowitz SD, Hsia J, Bonaca MP. Improvement in walking impairment following surgical and endovascular revascularization: Insights from VOYAGER PAD. Vasc Med. 2022 Aug;27(4):343-349.

Adenaeuer A, Barco S, Trinchero A, Lackner KJ, Lämmle B, Rossmann H. Definite diagnosis of plasma prekallikrein deficiency should not be based exclusively on shortening of the aPTT upon prolonged pre-incubation. Int J Lab Hematol. 2022 Aug;44(4):e179-e180.

Brandt M, Dörschmann H, Khraisat S, Knopp T, Ringen J, Kalinovic S, Garlapati V, Siemer S, Molitor M, Göbel S, Stauber R, Helena Karbach S, Münzel T, Daiber A, Wenzel P. Telomere Shortening in Hypertensive Heart Disease Depends on Oxidative DNA Damage and Predicts Impaired Recovery of Cardiac Function in Heart Failure. Hypertension. 2022 Jul 18:101161HYPERTENSIONAHA12118935.

Voci D, Zbinden S, Micieli E, Kucher N, Barco S. Fixed-Dose Ultrasound-Assisted Catheter-Directed Thrombolysis for Acute Pulmonary Embolism Associated with COVID-19. Viruses. 2022 Jul 22;14(8):1606.

Krenzlin V, Roewe J, Strueve M, Martínez-Negro M, Sharma A, Reinhardt C, Morsbach S, Bosmann M. Bacterial-Type Long-Chain Polyphosphates Bind Human Proteins in the Phosphatidylinositol Signaling Pathway. Thromb Haemost. 2022 Jul 30. 

Zuin M, Valerio L, Quadretti L, Zuliani G, Manfredini R, Rigatelli G, Barco S, Roncon L. Weekend effect and short-term mortality in patients with acute pulmonary embolism: systematic review and meta-analysis. J Cardiovasc Med (Hagerstown). 2022 Jul 21.

Falanga A, Leader A, Ambaglio C, Bagoly Z, Castaman G, Elalamy I, Lecumberri R, Niessner A, Pabinger I, Szmit S, Trinchero A, Ten Cate H, Rocca B. EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer. Hemasphere. 2022 Jul 13;6(8):e750.

Wild J, Keller K, Karbach S, Weinmann-Menke J, Münzel T, Hobohm L. Case-Fatality and Temporal Trends in Patients with Psoriasis and End-Stage Renal Disease. J Clin Med. 2022 Jul 26;11(15):4328.

Bochenek ML, Gogiraju R, Großmann S, Krug J, Orth J, Reyda S, Georgiadis GS, Spronk HM, Konstantinides S, Münzel T, Griffin JH, Wild P, Espinola-Klein C, Ruf W, Schäfer K. EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia. JCI Insight. 2022 Jul 22;7(14):e157701.

da Costa Marques R, Simon J, d'Arros C, Landfester K, Jurk K, Mailänder V. Proteomics reveals differential adsorption of angiogenic platelet lysate proteins on calcium phosphate bone substitute materials. Regen Biomater. 2022 Jul 5;9:rbac044.

Nagy M, Ten Cate H. What to expect from drug targeting factor XI? Cardiovasc Res. 2022 Jul 27;118(10):e72-e74.

Arnoldussen CWKP, Notten P, Brans R, Vroegindeweij D, Tick LW, van de Poel MHW, Wikkeling ORM, Vleming LJ, Koster A, Jie KG, Jacobs EMG, Planken N, Wittens CHA, Ten Cate H, Wildberger JE, Ten Cate-Hoek AJ. Clinical impact of assessing thrombus age using magnetic resonance venography prior to catheter-directed thrombolysis. Eur Radiol. 2022 Jul;32(7):4555-4564.

Pallares Robles A, Ten Cate V, Schulz A, Prochaska JH, Rapp S, Koeck T, Panova-Noeva M, Heitmeier S, Schwers S, Leineweber K, Seyfarth HJ, Opitz CF, Spronk H, Espinola-Klein C, Lackner KJ, Münzel T, Andrade-Navarro MA, Konstantinides SV, Ten Cate H, Wild PS. Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis. Sci Rep. 2022 Jun 13;12(1):9761.

Zhang L, Dietsche F, Seitaj B, Rojas-Charry L, Latchman N, Tomar D, Wüst RC, Nickel A, Frauenknecht KB, Schoser B, Schumann S, Schmeisser MJ, Vom Berg J, Buch T, Finger S, Wenzel P, Maack C, Elrod JW, Parys JB, Bultynck G, Methner A. TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy.https://pubmed.ncbi.nlm.nih.gov/35715207/ Life Sci Alliance. 2022 Jun 17;5(10):e202201478.

Fieß A, Urschitz MS, Nagler M, Nickels S, Marx-Groß S, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of birth weight with corneal aberrations in adulthood - Results from a population-based study. J Optom. 2022 Jun 25:S1888-4296(21)00054-6.

Yamashita Y, Morimoto T, Klok FA, Barco S, Nishimoto Y, Kato T, Ono K, Kimura T; COMMAND VTE Registry Investigators. Anticoagulation strategies and clinical outcomes after bleeding events during anticoagulation therapy for venous thromboembolism in the practice-based Japanese registry. J Thromb Thrombolysis. 2022 Jun 17.

Willers A, Swol J, van Kuijk SMJ, Buscher H, McQuilten Z, Ten Cate H, Rycus PT, McKellar S, Lorusso R, Tonna JE. HEROES V-A-HEmoRrhagic cOmplications in veno-arterial Extracorporeal life Support-Development and internal validation of a multivariable prediction model in adult patients. Artif Organs. 2022 Jun 16.

Eckelt A, Wichmann F, Bayer F, Eckelt J, Groß J, Opatz T, Jurk K, Reinhardt C, Kiouptsi K. Ethyl Hydroxyethyl Cellulose-A Biocompatible Polymer Carrier in Blood. Int J Mol Sci. 2022 Jun 9;23(12):6432.

Hess CN, Szarek M, Anand SS, Bauersachs RM, Patel MR, Debus ES, Nehler MR, Capell WH, Beckman JA, Piazza G, Henkin S, Bura-Rivière A, Lawall H, Roztocil K, Hsia J, Muehlhofer E, Berkowitz SD, Haskell LP, Bonaca MP. Rivaroxaban and Risk of Venous Thromboembolism in Patients With Symptomatic Peripheral Artery Disease After Lower Extremity Revascularization. JAMA Netw Open. 2022 Jun 1;5(6):e2215580

Hess CN, Baumgartner I, Anand SS, Nehler MR, Patel MR, Debus ES, Szarek M, Capell W, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM, Bonaca MP, Hsia J. Sex-Based Differences in Outcomes Following Peripheral Artery Revascularization: Insights From VOYAGER PAD. J Am Heart Assoc. 2022 Jun 21;11(12):e024655.

Otten D, Ernst M, Tibubos AN, Brähler E, Fleischer T, Schomerus G, Wild PS, Zöller D, Binder H, Kruse J, Johar H, Atasoy S, Grabe HJ, Ladwig KH, Münzel T, Völzke H, König J, Beutel ME. Does social support prevent suicidal ideation in women and men? Gender-sensitive analyses of an important protective factor within prospective community cohorts. J Affect Disord. 2022 Jun 1;306:157-166.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Relationships between coagulation factors and thrombin generation in a general population with arterial and venous disease background. Thromb J. 2022 Jun 8;20(1):32.

Zhong X, Wang T, Zhang W, Wang M, Xie Y, Dai L, He X, Madhusudhan T, Zeng H, Wang H. ERK/RSK-mediated phosphorylation of Y-box binding protein-1 aggravates diabetic cardiomyopathy by suppressing its interaction with deubiquitinase OTUB1. J Biol Chem. 2022 Jun;298(6):101989.

Huber Y, Schulz A, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Galle PR, Wild PS, Lackner KJ, Schattenberg JM. Prevalence and Risk Factors of Advanced Liver Fibrosis in a Population-Based Study in Germany. Hepatol Commun. 2022 Jun;6(6):1457-1466.

Hopf S, Heidt F, Korb CA, Schulz A, Münzel T, Wild PS, Beutel M, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Five-Year Cumulative Incidence and Progression of Myopic Maculopathy in a German Population. Ophthalmology. 2022 May;129(5):562-570.

Mazzolai L, Ageno W, Alatri A, Bauersachs R, Becattini C, Brodmann M, Emmerich J, Konstantinides S, Meyer G, Middeldorp S, Monreal M, Righini M, Aboyans V. Second consensus document on diagnosis and management of acute deep vein thrombosis: updated document elaborated by the ESC Working Group on aorta and peripheral vascular diseases and the ESC Working Group on pulmonary circulation and right ventricular function. Eur J Prev Cardiol. 2022 May 27;29(8):1248-1263.

Berkowitz SD, Bauersachs RM, Szarek M, Nehler MR, Debus ES, Patel MR, Anand SS, Capell WH, Hess CN, Hsia J, Leeper NJ, Brasil D, Mátyás L, Diaz R, Brodmann M, Muehlhofer E, Haskell LP, Bonaca MP. Prevention of arterial and venous thrombotic events in symptomatic peripheral arterial disease patients after lower extremity revascularization in the VOYAGER PAD trial: Dual anticoagulant/antiplatelet regimen vs antiplatelet therapy alone. J Thromb Haemost. 2022 May;20(5):1193-1205

Jurk K. Functional Diversity of Primed Platelets-Powered by Machine Learning. Thromb Haemost. 2022 May;122(5):661.

Valerio L, Fedeli U, Schievano E, Avossa F, Barco S. Decline in Overall Pulmonary Embolism-Related Mortality and Increasing Prevalence of Cancer-Associated Events in the Veneto Region (Italy), 2008-2019. Thromb Haemost. 2022 May;122(5):789-795.

Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2022 May;179(10):2086-2099.

Sanchez O, Charles-Nelson A, Ageno W, Barco S, Binder H, Chatellier G, Duerschmied D, Empen K, Ferreira M, Girard P, Huisman MV, Jiménez D, Katsahian S, Kozak M, Lankeit M, Meneveau N, Pruszczyk P, Petris A, Righini M, Rosenkranz S, Schellong S, Stefanovic B, Verhamme P, de Wit K, Vicaut E, Zirlik A, Konstantinides SV, Meyer G; PEITHO-3 Investigators. Reduced-Dose Intravenous Thrombolysis for Acute Intermediate-High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial. Thromb Haemost. 2022 May;122(5):857-866.

Chaudhary N, Jayaraman A, Reinhardt C, Campbell JD, Bosmann M. A single-cell lung atlas of complement genes identifies the mesothelium and epithelium as prominent sources of extrahepatic complement proteins. Mucosal Immunol. 2022 May;15(5):927-939.

Willers A, Swol J, van Kuijk SMJ, Buscher H, McQuilten Z, Ten Cate H, Rycus PT, McKellar S, Lorusso R, Tonna JE. HEROES V-V-HEmorRhagic cOmplications in Veno-Venous Extracorporeal life Support-Development and internal validation of multivariable prediction model in adult patients. Artif Organs. 2022 May;46(5):932-952.

Gehrke N, Wörns MA, Mann A, Hövelmeyer N, Waisman A, Straub BK, Galle PR, Schattenberg JM. Hepatocyte Bcl-3 protects from death-receptor mediated apoptosis and subsequent acute liver failure. Cell Death Dis. 2022 May 31;13(5):510.

Keller K, Sagoschen I, Schmitt VH, Sivanathan V, Espinola-Klein C, Lavie CJ, Münzel T, Hobohm L. Obesity and Its Impact on Adverse In-Hospital Outcomes in Hospitalized Patients With COVID-19. Front Endocrinol (Lausanne). 2022 May 2;13:876028

Keller K, Prochaska JH, Coldewey M, Göbel S, Schmitt VH, Hahad O, Ullmann A, Nagler M, Lamparter H, Espinola-Klein C, Münzel T, Wild PS. Atherosclerosis and Its Impact on the Outcomes of Patients with Deep Venous Thrombosis. Life (Basel). 2022 May 14;12(5):734.

Neuenschwander J, Sebastian T, Barco S, Spirk D, Kucher N. A novel management strategy for treatment of pelvic venous disorders utilizing a clinical screening score and non-invasive imaging. Vasa. 2022 May;51(3):182-189.

Pfeilschifter W, Lindhoff-Last E, Alhashim A, Zydek B, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, von Heymann C, Birschmann I, Beyer-Westendorf J, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators (Reversal Agent use in patients treated with Direct Oral Anticoagulants or vitamin K antagonists Registry). Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry. Neurol Res Pract. 2022 May 2;4(1):16.

Wild J, Ringen J, Bieler T, Knopp T, Lagrange J, Molitor M, Sies K, Kropp A, Keller K, Daiber A, Münzel T, Rauh M, Waisman A, Wenzel P, Titze J, Karbach S. Epicutaneous Application of Imiquimod to Model Psoriasis-Like Skin Disease Induces Water-Saving Aestivation Motifs and Vascular Inflammation. J Invest Dermatol. 2022 May 14:S0022-202X(22)00392-X

Greinacher A, Langer F, Schonborn L, Thiele T, Haddad M, Renne T, Rollin J, Gruel Y, Warkentin TE. Platelet-activating anti-PF4 antibodies mimic VITT antibodies in an unvaccinated patient with monoclonal gammopathy. Haematologica. 2022 May 1;107(5):1219-1221.

Jurk K, Rothenaicher KF, Groß K, Rossmann H, Weißer G, Schmidtmann I, Münzel T, Espinola-Klein C. Differential Inhibition of Platelet Reactivity by Dual Therapy With Aspirin and Low-Dose Rivaroxaban in Peripheral Arterial Disease: A Pilot Study. Front Cardiovasc Med. 2022 May 6;9:865166.

Sharma A, Noon JB, Kontodimas K, Garo LP, Platten J, Quinton LJ, Urban JF Jr, Reinhardt C, Bosmann M. IL-27 Enhances γδ T Cell-Mediated Innate Resistance to Primary Hookworm Infection in the Lungs. J Immunol. 2022 Apr 15;208(8):2008-2018

Mora D, Nieto JA, Mateo J, Bikdeli B, Barco S, Trujillo-Santos J, Soler S, Font L, Bosevski M, Monreal M; RIETE Investigators. Machine Learning to Predict Outcomes in Patients with Acute Pulmonary Embolism Who Prematurely Discontinued Anticoagulant Therapy. Thromb Haemost. 2022 Apr;122(4):570-577.

Wicke FS, Ernst M, Otten D, Werner A, Dreier M, Brähler E, Tibubos AN, Reiner I, Michal M, Wiltink J, Münzel T, Lackner KJ, Pfeiffer N, König J, Wild PS, Beutel ME. The association of depression and all-cause mortality: Explanatory factors and the influence of gender. J Affect Disord. 2022 Apr 15;303:315-322.

Otten D, Ernst M, Werner AM, Tibubos AN, Reiner I, Brähler E, Wiltink J, Michal M, Nagler M, Wild PS, Münzel T, König J, Lackner KJ, Peiffer N, Beutel ME. Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample. Psychol Med. 2022 Apr 21:1-9.

Spirk D, Sebastian T, Beer JH, Mazzolai L, Aujesky D, Hayoz D, Engelberger RP, Korte W, Kucher N, Barco S. Role of age, sex, and specific provoking factors on the distal versus proximal presentation of first symptomatic deep vein thrombosis: analysis of the SWIss Venous ThromboEmbolism Registry (SWIVTER). Intern Emerg Med. 2022 Apr;17(3):799-803.

Leberzammer J, Agten SM, Blanchet X, Duan R, Ippel H, Megens RTA, Schulz C, Aslani M, Duchene J, Döring Y, Jooss NJ, Zhang P, Brandl R, Stark K, Siess W, Jurk K, Heemskerk JWM, Hackeng TM, Mayo KH, Weber C, von Hundelshausen P. Targeting platelet-derived CXCL12 impedes arterial thrombosis. Blood. 2022 Apr 28;139(17):2691-2705.

Lammle B. A third form of thrombotic thrombocytopenic purpura? Haematologica. 2022 Apr 28

Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19;39(3):110714.

Schmitt VH, Hobohm L, Sivanathan V, Brochhausen C, Gori T, Münzel T, Konstantinides SV, Keller K. Diabetes mellitus and its impact on mortality rate and outcome in pulmonary embolism.https://pubmed.ncbi.nlm.nih.gov/34779148/ J Diabetes Investig. 2022 Apr;13(4):725-737

Hess CN, Capell WH, Bristow MR, Ruf W, Szarek M, Morrow DA, Nicolau JC, Graybill CA, Marshall D, Hsia J, Bonaca MP. Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial. Am Heart J. 2022 Apr;246:136-143

Schmitt VH, Hobohm L, Sivanathan V, Brochhausen C, Gori T, Münzel T, Konstantinides SV, Keller K. Diabetes mellitus and its impact on mortality rate and outcome in pulmonary embolism. J Diabetes Investig. 2022 Apr;13(4):725-737.

Douglas RS, Kahaly GJ, Ugradar S, Elflein H, Ponto KA, Fowler BT, Dailey R, Harris GJ, Schiffman J, Tang R, Wester S, Jain AP, Marcocci C, Marinò M, Antonelli A, Eckstein A, Führer-Sakel D, Salvi M, Sile S, Francis-Sedlak M, Holt RJ, Smith TJ. Teprotumumab Efficacy, Safety, and Durability in Longer-Duration Thyroid Eye Disease and Re-treatment: OPTIC-X Study. Ophthalmology. 2022 Apr;129(4):438-449.

Mauschitz MM, Schmitz MT, Verzijden T, Schmid M, Thee EF, Colijn JM, Delcourt C, Cougnard-Grégoire A, Merle BMJ, Korobelnik JF, Gopinath B, Mitchell P, Elbaz H, Schuster AK, Wild PS, Brandl C, Stark KJ, Heid IM, Günther F, Peters A, Klaver CCW, Finger RP; European Eye Epidemiology (E3) Consortium. Physical Activity, Incidence, and Progression of Age-Related Macular Degeneration: A Multicohort Study. Am J Ophthalmol. 2022 Apr;236:99-106.

Voci D, Fedeli U, Farmakis IT, Hobohm L, Keller K, Valerio L, Schievano E, Barbiellini Amidei C, Konstantinides SV, Kucher N, Barco S. Deaths related to pulmonary embolism and cardiovascular events before and during the 2020 COVID-19 pandemic: An epidemiological analysis of data from an Italian high-risk area. Thromb Res. 2022 Apr;212:44-50.

Masoodi M, Peschka M, Schmiedel S, Haddad M, Frye M, Maas C, Lohse A, Huber S, Kirchhof P, Nofer JR, Renné T. Disturbed lipid and amino acid metabolisms in COVID-19 patients. J Mol Med (Berl). 2022 Apr;100(4):555-568.

Valerio L, Mavromanoli AC, Barco S, Abele C, Becker D, Bruch L, Ewert R, Faehling M, Fistera D, Gerhardt F, Ghofrani HA, Grgic A, Grünig E, Halank M, Held M, Hobohm L, Hoeper MM, Klok FA, Lankeit M, Leuchte HH, Martin N, Mayer E, Meyer FJ, Neurohr C, Opitz C, Schmidt KH, Seyfarth HJ, Wachter R, Wilkens H, Wild PS, Konstantinides SV, Rosenkranz S; FOCUS Investigators. Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study. Eur Heart J. 2022 Apr 28:ehac206.

Halfmann MC, Benz S, Schoepf UJ, Düber C, Kloeckner R, Eichstaedt J, Wenzel P, Kreitner KF, Varga-Szemes A, Emrich T. Myocardial Mass Corrected CMR Feature Tracking-Based Strain Ratios are Different in Pathologies With Increased Myocardial Mass. Acad Radiol. 2022 Apr;29 Suppl 4:S40-S48.

Lindhoff-Last E, Birschmann I, Kuhn J, Lindau S, Konstantinides S, Grottke O, Nowak-Göttl U, Lucks J, Zydek B, von Heymann C, Sümnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A, Herrmann E; RADOA-Registry Investigators (Reversal Agent use in patients treated with Direct Oral Anticoagulants or vitamin K antagonists Registry). Pharmacokinetics of Direct Oral Anticoagulants in Emergency Situations: Results of the Prospective Observational RADOA-Registry. Thromb Haemost. 2022 Apr;122(4):552-559.

Ludt A, Ustjanzew A, Binder H, Strauch K, Marini F. Interactive and Reproducible Workflows for Exploring and Modeling RNA-seq Data with pcaExplorer, Ideal, and GeneTonic. Curr Protoc. 2022 Apr;2(4):e411.

Petersen EL, Goßling A, Adam G, Aepfelbacher M, Behrendt CA, Cavus E, Cheng B, Fischer N, Gallinat J, Kühn S, Gerloff C, Koch-Gromus U, Härter M, Hanning U, Huber TB, Kluge S, Knobloch JK, Kuta P, Schmidt-Lauber C, Lütgehetmann M, Magnussen C, Mayer C, Muellerleile K, Münch J, Nägele FL, Petersen M, Renné T, Riedl KA, Rimmele DL, Schäfer I, Schulz H, Tahir E, Waschki B, Wenzel JP, Zeller T, Ziegler A, Thomalla G, Twerenbold R, Blankenberg S. Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. Eur Heart J. 2022 Mar 14;43(11):1124-1137.

Ernst M, Brähler E, Faber J, Wild PS, Merzenich H, Beutel ME. A Mixed-Methods Investigation of Medical Follow-Up in Long-Term Childhood Cancer Survivors: What Are the Reasons for Non-Attendance? Front Psychol. 2022 Mar 14;13:846671.

Micieli E, Voci D, Mumoli N, Mastroiacovo D, Grigorean A, Obadia M, de Champfleur NM, Naggara O, Carsin B, Amor-Sahli M, Cottier JP, Bensoussan J, Auffray-Calvier E, Varoquaux A, Bonneville F, Sadik JC, Kucher N, Lecler A, Barco S. Transient perivascular inflammation of the carotid artery (TIPIC) syndrome. Vasa. 2022 Mar;51(2):71-77.

Sanders NL, Martin IMC, Sharma A, Jones MR, Quinton LJ, Bosmann M, Mizgerd JP. Neutrophil Extracellular Traps as an Exacerbating Factor in Bacterial Pneumonia. Infect Immun. 2022 Mar 17;90(3):e0049121

Pohl KR, Hobohm L, Krieg VJ, Sentler C, Rogge NIJ, Steimke L, Ebner M, Lerchbaumer M, Hasenfuß G, Konstantinides S, Lankeit M, Keller K. Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism. Thromb Res. 2022 Mar;211:70-78.

Mooz J, Riegel K, Ps H, Sadanandam A, Marini F, Klein M, Werner U, Roth W, Wilken-Schmitz A, Tegeder I, Rajalingam K. ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers. Sci Adv. 2022 Mar 18;8(11):eabk1538

Keller K, Hobohm L, Münzel T, Lankeit M, Konstantinides S, Ostad MA. Impact of Systemic Atherosclerosis on Clinical Characteristics and Short-Term Outcomes in Patients with Deep Venous Thrombosis or Thrombophlebitis. Am J Med Sci. 2022 Mar;363(3):232-241.

Lüscher TF, Davies A, Beer JH, Valgimigli M, Nienaber CA, Camm JA, Baumgartner I, Diener HC, Konstantinides SV. Towards personalized antithrombotic management with drugs and devices across the cardiovascular spectrum. Eur Heart J. 2022 Mar 7;43(10):940-958

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535

Schmitt VH, Leuschner A, Jünger C, Pinto A, Hahad O, Schulz A, Arnold N, Tröbs SO, Panova-Noeva M, Keller K, Zeller T, Beutel M, Pfeiffer N, Strauch K, Blankenberg S, Lackner KJ, Prochaska JH, Wild PS, Münzel T. Cardiovascular profiling in the diabetic continuum: results from the population-based Gutenberg Health Study. Clin Res Cardiol. 2022 Mar;111(3):272-283.

Jünger C, Prochaska JH, Gori T, Schulz A, Binder H, Daiber A, Koeck T, Rapp S, Lackner KJ, Münzel T, Wild PS. Rationale and design of the effects of EMpagliflozin on left ventricular DIAstolic function in diabetes (EmDia) study. J Cardiovasc Med (Hagerstown). 2022 Mar 1;23(3):191-197.

Panova-Noeva M, Wagner B, Nagler M, Koeck T, Ten Cate V, Eggebrecht L, Prochaska JH, Meyer I, Gerdes C, Spronk HM, Lackner KJ, Ten Cate H, Leineweber K, Heitmeier S, Konstantinides S, Wild PS. Variation of platelet function in clinical phenotypes of acute venous thromboembolism - Results from the GMP-VTE project. J Thromb Haemost. 2022 Mar;20(3):705-715.

Eichstaedt CA, Saßmannshausen Z, Shaukat M, Cao D, Xanthouli P, Gall H, Sommer N, Ghofrani HA, Seyfarth HJ, Lerche M, Halank M, Kleymann J, Benjamin N, Harutyunova S, Egenlauf B, Milger K, Rosenkranz S, Ewert R, Klose H, Hoeper MM, Olsson KM, Lankeit M, Lange TJ, Hinderhofer K, Grünig E. Gene panel diagnostics reveals new pathogenic variants in pulmonary arterial hypertension. Respir Res. 2022 Mar 27;23(1):74.

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535.

Wild J, Siegrist B, Hobohm L, Münzel T, Schwanz T, Sagoschen I. Short and Concise Peer-to-Peer Teaching-Example of a Successful Antibiotic Stewardship Intervention to Increase Iv to Po Conversion. Antibiotics (Basel). 2022 Mar 17;11(3):402.

Stamm P, Kalinovic S, Oelze M, Steven S, Czarnowski A, Kvandova M, Bayer F, Reinhardt C, Münzel T, Daiber A. Mechanistic Insights into Inorganic Nitrite-Mediated Vasodilation of Isolated Aortic Rings under Oxidative/Hypertensive Conditions and S-Nitros(yl)ation of Proteins in Germ-Free Mice. Biomedicines. 2022 Mar 21;10(3):730.

Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 Mar 5;14(3):535.

Wallis S, Wolska N, Englert H, Posner M, Upadhyay A, Renné T, Eggleston I, Bagby S, Pula G. A peptide from the staphylococcal protein Efb binds P-selectin and inhibits the interaction of platelets with leukocytes. J Thromb Haemost. 2022 Mar;20(3):729-741.

Wendelboe AM, Langenfeld H, Ageno W, Castellucci L, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Forgo G, Guillermo Esposito MC, McLintock C, Ní Áinle F, Spyropoulos AC, Urano T, Barco S, Hunt BJ. Current practices of standardized risk assessment for venous thromboembolism: Results from a global survey from the World Thrombosis Day steering committee. J Thromb Haemost. 2022 Feb;20(2):532-535.

Arnold N, Hermanns IM, Schulz A, Hahad O, Schmitt VH, Panova-Noeva M, Prochaska JH, Binder H, Pfeiffer N, Beutel M, Lackner KJ, Münzel T, Wild PS. Renin, aldosterone, the aldosterone-to-renin ratio, and incident hypertension among normotensive subjects from the general population. Cardiovasc Res. 2022 Feb 23:cvac019.

Sanrattana W, Smits S, Barendrecht AD, van Kleef ND, El Otmani H, Zivkovic M, Roest M, Renné T, Clark CC, de Maat S, Maas C. Targeted SERPIN (TaSER): A dual-action antithrombotic agent that targets platelets for SERPIN delivery. J Thromb Haemost. 2022 Feb;20(2):353-365.

Kreuzpointner R, Valerio L, Corsi G, Zane F, Sacco C, Holm K, Righini C, Pecci A, Zweifel S, Barco S. Ophthalmic complications of Lemierre syndrome. Acta Ophthalmol. 2022 Feb;100(1):e314-e320.

Shahneh F, Christian Probst H, Wiesmann SC, A-Gonzalez N, Ruf W, Steinbrink K, Raker VK, Becker C. Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and Resolution. Arterioscler Thromb Vasc Biol. 2022 Feb;42(2):145-155.

Schnabel RB, Magnussen C, Schulz A, Ojeda FM, Schmitt VH, Arnold N, Sinning CR, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Lackner KJ, Gori T, Benjamin EJ, Binder H, Wild PS, Blankenberg S, Münzel T; Gutenberg Health Study investigators. Non-invasive peripheral vascular function, incident cardiovascular disease, and mortality in the general population. Cardiovasc Res. 2022 Feb 21;118(3):904-912.

Blessing RRL, Ahoopai M, Geyer M, Brandt M, Zeiher AM, Vasa-Nicotera M, Münzel T, Wenzel P, Gori T, Dimitriadis Z. Percutaneous coronary intervention for chronic total occlusion in octogenarians: a propensity score study. Sci Rep. 2022 Feb 23;12(1):3073.

Hrdinova J, Fernández DI, Ercig B, Tullemans BME, Suylen DPL, Agten SM, Jurk K, Hackeng TM, Vanhoorelbeke K, Voorberg J, Reutelingsperger CPM, Wichapong K, Heemskerk JWM, Nicolaes GAF. Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear. Int J Mol Sci. 2022 Feb 12;23(4):2046.

Forgo G, Micieli E, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Guillermo Esposito MC, Konstantinides SV, Kucher N, McLintock C, Ní Áinle F, Spyropoulos AC, Urano T, Hunt BJ, Barco S. An update on the global use of risk assessment models and thromboprophylaxis in hospitalized patients with medical illnesses from the World Thrombosis Day steering committee: Systematic review and meta-analysis. J Thromb Haemost. 2022 Feb;20(2):409-421.

Kouz K, Bergholz A, Diener O, Leistenschneider M, Thompson C, Pichotka F, Trepte C, Schwedhelm E, Renné T, Krause L, Nicklas JY, Saugel B. Effect of intraoperative personalized goal-directed hemodynamic management on acute myocardial injury in high-risk patients having major abdominal surgery: a post-hoc secondary analysis of a randomized clinical trial. J Clin Monit Comput. 2022 Feb 24.

Wegner J, Karbach S, Drosos I, Schnorbus B, Muxel S, Schmidt F, Wenzel P, Waisman A, Münzel T, Gori T, von Stebut E. TNF-α blockade may lead to improvement of vascular function in psoriasis patients. Exp Dermatol. 2022 Feb;31(2):237-241.

Efentakis P, Molitor M, Kossmann S, Bochenek ML, Wild J, Lagrange J, Finger S, Jung R, Karbach S, Schäfer K, Schulz A, Wild P, Münzel T, Wenzel P. Tubulin-folding cofactor E deficiency promotes vascular dysfunction by increased endoplasmic reticulum stress. Eur Heart J. 2022 Feb 10;43(6):488-500.

Willems LH, Nagy M, Ten Cate H, Spronk HMH, Groh LA, Leentjens J, Janssen NAF, Netea MG, Thijssen DHJ, Hannink G, van Petersen AS, Warlé MC. Sustained inflammation, coagulation activation and elevated endothelin-1 levels without macrovascular dysfunction at 3 months after COVID-19. Thromb Res. 2022 Jan;209:106-114.

Nuebling M, Hegewald J, Starke KR, Lincke HJ, Jankowiak S, Liebers F, Latza U, Letzel S, Riechmann-Wolf M, Gianicolo E, Beutel M, Pfeiffer N, Lackner K, Münzel T, Wild PS, Seidler A. The Gutenberg health study: a five-year prospective analysis of psychosocial working conditions using COPSOQ (Copenhagen psychosocial Questoinnaire) and ERI (effort-reward imbalance). BMC Public Health. 2022 Jan 6;22(1):24.

Zhang W, Wang M, Gao K, Zhong X, Xie Y, Dai L, Liu W, Liu Y, He X, Li S, Madhusudhan T, Wang H, Zeng H. Pharmacologic IRE1α kinase inhibition alleviates aortic dissection by decreasing vascular smooth muscle cells apoptosis. Int J Biol Sci. 2022 Jan 1;18(3):1053-1064.

Hobohm L, Sagoschen I, Barco S, Schmidtmann I, Espinola-Klein C, Konstantinides S, Münzel T, Keller K. Trends and Risk Factors of In-Hospital Mortality of Patients with COVID-19 in Germany: Results of a Large Nationwide Inpatient Sample. Viruses. 2022 Jan 28;14(2):275

Wiedenroth CB, Bandorski D, Ariobi K, Ghofrani HA, Lankeit M, Liebetrau C, Pruefer D, Mayer E, Kriechbaum SD, Guth S. Does Age Matter? Pulmonary Endarterectomy in the Elderly Patient with CTEPH. Thorac Cardiovasc Surg. 2022 Jan 17.

Hoffmann EM, Aghayeva F, Wagner FM, Fiess A, Nagler M, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Intraocular Pressure and Its Relation to Ocular Geometry: Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):40.

Frenis K, Kalinovic S, Ernst BP, Kvandova M, Al Zuabi A, Kuntic M, Oelze M, Stamm P, Bayo Jimenez MT, Kij A, Keppeler K, Klein V, Strohm L, Ubbens H, Daub S, Hahad O, Kröller-Schön S, Schmeisser MJ, Chlopicki S, Eckrich J, Strieth S, Daiber A, Steven S, Münzel T. Long-Term Effects of Aircraft Noise Exposure on Vascular Oxidative Stress, Endothelial Function and Blood Pressure: No Evidence for Adaptation or Tolerance Development. Front Mol Biosci. 2022 Jan 31;8:814921.

Heidorn MW, Steck S, Müller F, Tröbs SO, Buch G, Schulz A, Schwuchow-Thonke S, Schuch A, Strauch K, Schmidtmann I, Lackner KJ, Gori T, Münzel T, Wild PS, Prochaska JH. FEV1 Predicts Cardiac Status and Outcome in Chronic Heart Failure. Chest. 2022 Jan;161(1):179-189.

Zuin M, Engelen MM, Barco S, Spyropoulos AC, Vanassche T, Hunt BJ, Vandenbriele C, Verhamme P, Kucher N, Rashidi F, Zuliani G, Konstantinides SV, Roncon L. Incidence of venous thromboembolic events in COVID-19 patients after hospital discharge: A systematic review and meta-analysis. Thromb Res. 2022 Jan;209:94-98.

Turatti G, Fedeli U, Valerio L, Klok FA, Cohen AT, Hunt BJ, Simioni P, Middeldorp S, Ageno W, Kucher N, Konstantinides SV, Schievano E, Barco S. Splanchnic vein thrombosis-related mortality in the Veneto region (Italy), 2008-2019: Retrospective analysis of epidemiological data. Thromb Res. 2022 Jan;209:41-46.

Maifeld A, Wild J, Karlsen TV, Rakova N, Wistorf E, Linz P, Jung R, Birukov A, Gimenez-Rivera VA, Wilck N, Bartolomaeus T, Dechend R, Kleinewietfeld M, Forslund SK, Krause A, Kokolakis G, Philipp S, Clausen BE, Brand A, Waisman A, Kurschus FC, Wegner J, Schultheis M, Luft FC, Boschmann M, Kelm M, Wiig H, Kuehne T, Müller DN, Karbach S, Markó L. Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. J Invest Dermatol. 2022 Jan;142(1):166-178.e8.

Hobohm L, Sagoschen I, Habertheuer A, Barco S, Valerio L, Wild J, Schmidt FP, Gori T, Münzel T, Konstantinides S, Keller K. Clinical use and outcome of extracorporeal membrane oxygenation in patients with pulmonary embolism. Resuscitation. 2022 Jan;170:285-292.

Merzenich H, Baaken D, Schneider A, Neu MA, Wingerter A, Faber J, Wild PS, Spix C. Mortality risk among 5-year survivors of childhood cancer in Germany-Results from the CVSS study (Cardiac and Vascular late Sequelae in long-term Survivors of childhood cancer study). Int J Cancer. 2022 Jan 1;150(1):67-72.

Klok FA, Ageno W, Ay C, Bäck M, Barco S, Bertoletti L, Becattini C, Carlsen J, Delcroix M, van Es N, Huisman MV, Jara-Palomares L, Konstantinides S, Lang I, Meyer G, Ní Áinle F, Rosenkranz S, Pruszczyk P. Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society. Eur Heart J. 2022 Jan 25;43(3):183-189.

Korb CA, Elbaz H, Schuster AK, Nickels S, Ponto KA, Schulz A, Wild PS, Münzel T, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N. Five-year cumulative incidence and progression of age-related macular degeneration: results from the German population-based Gutenberg Health Study (GHS). Graefes Arch Clin Exp Ophthalmol. 2022 Jan;260(1):55-64.



Reviews 2022

Subramaniam S, Kothari H, Bosmann M. Tissue factor in COVID-19-associated coagulopathy. Thromb Res. 2022 Dec;220:35-47.

Khan ES, Danckwardt S. Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond. Genes (Basel). 2022 Nov 22;13(12):2181

Wauthier L, Favresse J, Hardy M, Douxfils J, Le Gal G, Roy PM, van Es N, Ay C, Ten Cate H, Vander Borght T, Dupont MV, Lecompte T, Lippi G, Mullier F. D-dimer Testing in Pulmonary Embolism with a Focus on Potential Pitfalls: A Narrative Review. Diagnostics (Basel). 2022 Nov 12;12(11):2770

Nagy M, van der Meijden PEJ, Glunz J, Schurgers L, Lutgens E, Ten Cate H, Heitmeier S, Spronk HMH. Integrating Mechanisms in Thrombotic Peripheral Arterial Disease. https://pubmed.ncbi.nlm.nih.gov/36422558/Pharmaceuticals (Basel). 2022 Nov 18;15(11):1428

Gorog DA, Gue YX, Chao TF, Fauchier L, Ferreiro JL, Huber K, Konstantinidis SV, Lane DA, Marin F, Oldgren J, Potpara T, Roldan V, Rubboli A, Sibbing D, Tse HF, Vilahur G, Lip GYH. Assessment and Mitigation of Bleeding Risk in Atrial Fibrillation and Venous Thromboembolism: Executive Summary of a European and Asia-Pacific Expert Consensus Paper. Thromb Haemost. 2022 Oct;122(10):1625-1652.


Gwozdz AM, de Jong CMM, Fialho LS, Likitabhorn T, Sossi F, Jaber PB, Højen AA, Arcelus JI, Auger WR, Ay C, Barco S, Gazzana MB, Bayley J, Bertoletti L, Cate-Hoek AT, Cohen AT, Connors JM, Galanaud JP, Labropoulos N, Langlois N, Meissner MH, Noble S, Nossent EJ, de León Lovatón PP, Robert-Ebadi H, Rosovsky RP, Smolenaars N, Toshner M, Tromeur C, Wang KL, Westerlund E, de Wit K, Black SA, Klok FA. Development of an international standard set of outcome measures for patients with venous thromboembolism: an International Consortium for Health Outcomes Measurement consensus recommendation. Lancet Haematol. 2022 Sep;9(9):e698-e706.

Hobohm L, Farmakis IT, Keller K, Scibior B, Mavromanoli AC, Sagoschen I, Münzel T, Ahrens I, Konstantinides S. Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis. Clin Res Cardiol. 2022 Aug 17:1–11.

Willems LH, Maas DPMSM, Kramers K, Reijnen MMPJ, Riksen NP, Ten Cate H, van der Vijver-Coppen RJ, de Borst GJ, Mees BME, Zeebregts CJ, Hannink G, Warlé MC. Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis. Drugs. 2022 Aug 23.

Gorog DA, Storey RF, Gurbel PA, Tantry US, Berger JS, Chan MY, Duerschmied D, Smyth SS, Parker WAE, Ajjan RA, Vilahur G, Badimon L, Berg JMT, Cate HT, Peyvandi F, Wang TT, Becker RC. Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium. Nat Rev Cardiol. 2022 Jul;19(7):475-495

Mast AE, Ruf W. Regulation of coagulation by tissue factor pathway inhibitor: Implications for hemophilia therapy. J Thromb Haemost. 2022 Jun;20(6):1290-1300

Task Force for the management of COVID-19 of the European Society of Cardiology. ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2-care pathways, treatment, and follow-up. Cardiovasc Res. 2022 Jun 22;118(7):1618-1666.

Zwirner J, Kulakofsky R, Fitzek A, Schröder AS, Bohnert S, Franke H, Renné T, Tse R, Ondruschka B. Forensic biomarkers of lethal traumatic brain injury. Int J Legal Med. 2022 May;136(3):871-886.

Paeslack N, Mimmler M, Becker S, Gao Z, Khuu MP, Mann A, Malinarich F, Regen T, Reinhardt C. Microbiota-derived tryptophan metabolites in vascular inflammation and cardiovascular disease. Amino Acids. 2022 Apr 22.

Spada S, Luke B, Danckwardt S. The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen. Front Genet. 2022 Apr 28;13:854907

Mendelsohn DH, Schnabel K, Mamilos A, Sossalla S, Pabel S, Duerr GD, Keller K, Schmitt VH, Barsch F, Walter N, Wong RMY, El Khassawna T, Niedermair T, Alt V, Rupp M, Brochhausen C. Structural Analysis of Mitochondrial Dynamics-From Cardiomyocytes to Osteoblasts: A Critical Review. Int J Mol Sci. 2022 Apr 20;23(9):4571

Wang H, Karnati S, Madhusudhan T. Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy. Pharmaceuticals (Basel). 2022 Mar 25;15(4):401.

Mandel J, Casari M, Stepanyan M, Martyanov A, Deppermann C. Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation. https://pubmed.ncbi.nlm.nih.gov/35409226/Int J Mol Sci. 2022 Mar 31;23(7):3868.

Hobohm L, Farmakis IT, Münzel T, Konstantinides S, Keller K. Pulmonary Embolism and Pregnancy-Challenges in Diagnostic and Therapeutic Decisions in High-Risk Patients. Front Cardiovasc Med. 2022 Mar 8;9:856594.

Dauwerse S, Ten Cate H, Spronk HMH, Nagy M. The Composition and Physical Properties of Clots in COVID-19 Pathology. Diagnostics (Basel). 2022 Feb 24;12(3):580

Helmstädter J, Keppeler K, Küster L, Münzel T, Daiber A, Steven S. Glucagon-like peptide-1 (GLP-1) receptor agonists and their cardiovascular benefits-The role of the GLP-1 receptor. Br J Pharmacol. 2022 Feb;179(4):659-676.

Mailer RK, Kuta P, Renné T. An Update on Safe Anticoagulation. Hamostaseologie. 2022 Feb;42(1):65-72

Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. An update on factor XII-driven vascular inflammation. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.

Klok FA, Pai M, Huisman MV, Makris M. Vaccine-induced immune thrombotic thrombocytopenia. Lancet Haematol. 2022 Jan;9(1):e73-e80

Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. An update on factor XII-driven vascular inflammation. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166.



Editorials und Fachbeiträge 2022

Barco S, Schreiber K. COVID-19: ACT trials for colchicine and antithrombotic therapies. Lancet Respir Med. 2022 Dec;10(12):1106-1108

Luo Q, Wenzel P. Properdin (factor P) as a new target cleaved by factor XIa: Intrinsic coagulation at the crossroads with inflammation. Res Pract Thromb Haemost. 2022 Nov 4;6(7):e12835

Wenzel P. Thromboinflammation in cardiovascular disease: lessons learned for the management of hypertension, heart failure, and aortic valve stenosis. Eur Heart J. 2022 Nov 21;43(44):4611-4613

Gorog DA, Gue YX, Chao TF, Fauchier L, Ferreiro JL, Huber K, Konstantinidis SV, Lane DA, Marin F, Oldgren J, Potpara T, Roldan V, Rubboli A, Sibbing D, Tse HF, Vilahur G, Lip GYH. Assessment and mitigation of bleeding risk in atrial fibrillation and venous thromboembolism: A Position Paper from the ESC Working Group on Thrombosis, in collaboration with the European Heart Rhythm Association, the Association for Acute CardioVascular Care and the Asia-Pacific Heart Rhythm Society. Europace. 2022 Nov 22;24(11):1844-1871

Adenaeuer A, Barco S, Trinchero A, Lackner KJ, Lämmle B, Rossmann H. Definite diagnosis of plasma prekallikrein deficiency should not be based exclusively on shortening of the aPTT upon prolonged pre-incubation. Int J Lab Hematol. 2022 Aug;44(4):e179-e180

Haghikia A, van Mens TE, Pontarollo G, Reinhardt C. Editorial: Impact of the gut microbiota on cardiovascular medicine. Front Med (Lausanne). 2022 Jul 13;9:939890.

Mailer RK, Renné T. Commentary on "Pharmacological profile of asundexian, a novel, orally bioavailable inhibitor of factor XIa": Small molecule factor XIa inhibitor asundexian allows for safer anticoagulation. J Thromb Haemost. 2022 Jun;20(6):1309-1311

Koizume S, Kobayashi S, Ruf W, Miyagi Y. Authors' reply to the Letter to the Editor: Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer. Cancer Sci. 2022 May;113(5):1888-1890.

Anand SS, Hiatt W, Dyal L, Bauersachs R, Berkowitz SD, Branch KRH, Debus S, Fox KAA, Liang Y, Muehlhofer E, Nehler M, Haskell LP, Patel M, Szarek M, Yusuf S, Eikelboom J, Bonaca MP. Low-dose rivaroxaban and aspirin among patients with peripheral artery disease: a meta-analysis of the COMPASS and VOYAGER trials. Eur J Prev Cardiol. 2022 May 5;29(5):e181-e189.

Kuijpers MJE, Heemskerk JWM, Jurk K. Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation. Int J Mol Sci. 2022 May 23;23(10):5825.

Panova-Noeva M, Falanga A. Editorial: Role of the Platelet Phenomenon in Cardiovascular Diseases and Cancer. Front Cardiovasc Med. 2022 Mar 23;9:859770.

ICM-VTE General Delegates. Recommendations from the ICM-VTE: General. J Bone Joint Surg Am. 2022 Mar 16;104(Suppl 1):4-162.

Pontarollo G, Kiouptsi K, Bayer F, Reinhardt C, 2022. In: Glibetic, M. (Ed.), Comprehensive Gut Microbiota, vol. 2. Elsevier, pp. 319–338.

Spaetgens B, Nagy M, Ten Cate H. Antiplatelet Therapy in Patients With COVID-19-More Is Less? JAMA. 2022 Jan 18;327(3):223-224.

Originalartikel 2021

Marini F, Ludt A, Linke J, Strauch K. GeneTonic: an R/Bioconductor package for streamlining the interpretation of RNA-seq data. BMC Bioinformatics. 2021 Dec 23;22(1):610.

Hobohm L, Kölmel S, Niemann C, Kümpers P, Krieg VJ, Bochenek ML, Lukasz AH, Reiss Y, Plate KH, Liebetrau C, Wiedenroth CB, Guth S, Münzel T, Hasenfuß G, Wenzel P, Mayer E, Konstantinides SV, Schäfer K, Lankeit M. Role of angiopoietin-2 in venous thrombus resolution and chronic thromboembolic disease. Eur Respir J. 2021 Dec 2;58(6):2004196.

Sebastian T, Barco S, Kreuzpointner R, Konstantinides S, Kucher N. Reversal of cardiopulmonary exercise intolerance in patients with post-thrombotic obstruction of the inferior vena cava. Thromb Res. 2021 Dec;208:219-225.

Hess CN, Debus ES, Nehler MR, Anand SS, Patel MR, Szarek M, Capell WH, Hsia J, Beckman JA, Brodmann M, Diaz R, Habertheuer P, Leeper NJ, Powell RJ, Sillesen H, Muehlhofer E, Berkowitz SD, Haskell LP, Bauersachs RM, Bonaca MP. Reduction in Acute Limb Ischemia With Rivaroxaban Versus Placebo in Peripheral Artery Disease After Lower Extremity Revascularization: Insights From VOYAGER PAD. Circulation. 2021 Dec 7;144(23):1831-1841.

Iglesias MJ, Kruse LD, Sanchez-Rivera L, Enge L, Dusart P, Hong MG, Uhlén M, Renné T, Schwenk JM, Bergstrom G, Odeberg J, Butler LM. Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors. Arterioscler Thromb Vasc Biol. 2021 Dec;41(12):2990-3004.

Geyer M, Keller K, Tamm AR, Born S, Bachmann K, Ruf TF, Kreidel F, Hahad O, Petrescu A, Schnitzler K, Schmitt VH, da Rocha E Silva JG, Hell MM, Schulz E, Münzel T, von Bardeleben RS. Early symptomatic benefit indicates long-term prognosis after transcatheter mitral valve edge-to-edge repair in functional and degenerative etiology. Int J Cardiol. 2021 Dec 1;344:141-146.

Schnorbus B, Jurk K, Lackner KJ, Welk C, Münzel T, Gori T. Effects of Clopidogrel, Prasugrel and Ticagrelor on Microvascular Function and Platelet Reactivity in Patients With Acute Coronary Syndrome Undergoing Coronary Artery Stenting. A Randomized, Blinded, Parallel Group Trial. Front Cardiovasc Med. 2021 Dec 13;8:780605.

Pływaczewska M, Jiménez D, Lankeit M, Pruszczyk P, Kostrubiec M. A Comparison of GFR Calculated by Cockcroft-Gault vs. MDRD Formula in the Prognostic Assessment of Patients with Acute Pulmonary Embolism. Dis Markers. 2021 Dec 8;2021:6655958.

Willems LH, Nagy M, Ten Cate H, Spronk HMH, Jacobs LMC, Kranendonk J, van Leeuwen M, Meijer D, Middeldorp S, Groh LA, Warlé MC. ChAdOx1 vaccination, blood coagulation, and inflammation: No effect on coagulation but increased interleukin-6. Res Pract Thromb Haemost. 2021 Dec 7;5(8):e12630.

Kaemmerer AS, Gorenflo M, Huscher D, Pittrow D, Ewert P, Pausch C, Delcroix M, Ghofrani HA, Hoeper MM, Kozlik-Feldmann R, Skride A, Stähler G, Vizza CD, Jureviciene E, Jancauskaite D, Gumbiene L, Ewert R, Dähnert I, Held M, Halank M, Skowasch D, Klose H, Wilkens H, Milger K, Jux C, Koestenberger M, Scelsi L, Brunnemer E, Hofbeck M, Ulrich S, Vonk Noordegraaf A, Lange TJ, Bruch L, Konstantinides S, Claussen M, Löffler-Ragg J, Wirtz H, Apitz C, Neidenbach R, Freilinger S, Nemes A, Opitz C, Grünig E, Rosenkranz S. Medical treatment of pulmonary hypertension in adults with congenital heart disease: updated and extended results from the International COMPERA-CHD Registry. Cardiovasc Diagn Ther. 2021 Dec;11(6):1255-1268.

Greinacher A, Selleng K, Palankar R, Wesche J, Handtke S, Wolff M, Aurich K, Lalk M, Methling K, Völker U, Hentschker C, Michalik S, Steil L, Reder A, Schönborn L, Beer M, Franzke K, Büttner A, Fehse B, Stavrou EX, Rangaswamy C, Mailer RK, Englert H, Frye M, Thiele T, Kochanek S, Krutzke L, Siegerist F, Endlich N, Warkentin TE, Renné T. Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia. Blood. 2021 Dec 2;138(22):2256-2268.

Fieß A, Urschitz MS, Marx-Groß S, Nagler M, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of Birth Weight with Central and Peripheral Corneal Thickness in Adulthood-Results from the Population-Based German Gutenberg Health Study. Children (Basel). 2021 Nov 4;8(11):1006.

Hess CN, Patel MR, Bauersachs RM, Anand SS, Debus ES, Nehler MR, Fanelli F, Yeh RW, Secemsky EA, Beckman JA, Mauri L, Govsyeyev N, Capell WH, Brackin T, Berkowitz SD, Muehlhofer E, Haskell LP, Hiatt WR, Bonaca MP. Safety and Effectiveness of Paclitaxel Drug-Coated Devices in Peripheral Artery Revascularization: Insights From VOYAGER PAD. J Am Coll Cardiol. 2021 Nov 2;78(18):1768-1778.

Keller K, Hobohm L, Ostad MA, Karbach S, Espinola-Klein C, Münzel T, Gelfand JM, Konstantinides SV, Steinbrink K, Gori T. Psoriasis and its impact on the clinical outcome of patients with pulmonary embolism. Int J Cardiol. 2021 Nov 15;343:114-121.

Fieß A, Wagner FM, Urschitz MS, Nagler M, Stoffelns B, Wild PS, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Association of Birth Weight With Foveolar Thickness in Adulthood: Results From a Population-Based Study. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):9.

Siemer S, Bauer TA, Scholz P, Breder C, Fenaroli F, Harms G, Dietrich D, Dietrich J, Rosenauer C, Barz M, Becker S, Strieth S, Reinhardt C, Fauth T, Hagemann J, Stauber RH. Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin. ACS Nano. 2021 Nov 5.

Stamm P, Kirmes I, Palmer A, Molitor M, Kvandova M, Kalinovic S, Mihalikova D, Reid G, Wenzel P, Münzel T, Daiber A, Jansen T. Doxorubicin induces wide-spread transcriptional changes in the myocardium of hearts distinguishing between mice with preserved and impaired cardiac function. Life Sci. 2021 Nov 1;284:119879.

Keller K, Sinning C, Schulz A, Jünger C, Schmitt VH, Hahad O, Zeller T, Beutel M, Pfeiffer N, Strauch K, Blankenberg S, Lackner KJ, Prochaska JH, Schulz E, Münzel T, Wild PS. Right atrium size in the general population. Sci Rep. 2021 Nov 18;11(1):22523.

Xia N, Hasselwander S, Reifenberg G, Habermeier A, Closs EI, Mimmler M, Jung R, Karbach S, Lagrange J, Wenzel P, Daiber A, Münzel T, Hövelmeyer N, Waisman A, Li H. B Lymphocyte-Deficiency in Mice Causes Vascular Dysfunction by Inducing Neutrophilia. Biomedicines. 2021 Nov 14;9(11):1686.

Keller K, Wöllner J, Schmitt VH, Ostad MA, Sagoschen I, Münzel T, Espinola-Klein C, Hobohm L. Risk Factors for Pulmonary Embolism in Patients with Paralysis and Deep Venous Thrombosis. J Clin Med. 2021 Nov 19;10(22):5412.

D'Alessandro E, Scaf B, van Oerle R, van Nieuwenhoven FA, van Hunnik A, Verheule S, Schotten U, Ten Cate H, Spronk HMH. Thrombin generation by calibrated automated thrombography in goat plasma: Optimization of an assay. Res Pract Thromb Haemost. 2021 Nov 21;5(8):e12620.

Nevo N, Ordonez-Moreno LA, Gur-Cohen S, Avemaria F, Bhattacharya S, Khatib-Massalha E, Bertagna M, Haddad M, Chakrabarti P, Ruf W, Lapidot T, Kollet O. Enhanced thrombin/PAR1 activity promotes G-CSF- and AMD3100-induced mobilization of hematopoietic stem and progenitor cells via NO upregulation. Leukemia. 2021 Nov;35(11):3334-3338.

Kobayashi S, Koizume S, Takahashi T, Ueno M, Oishi R, Nagashima S, Sano Y, Fukushima T, Tezuka S, Morimoto M, Nakamura S, Narimatsu H, Ruf W, Miyagi Y. Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer. Cancer Sci. 2021 Nov;112(11):4679-4691.

D'Alessandro E, Scaf B, Munts C, van Hunnik A, Trevelyan CJ, Verheule S, Spronk HMH, Turner NA, Ten Cate H, Schotten U, van Nieuwenhoven FA. Coagulation Factor Xa Induces Proinflammatory Responses in Cardiac Fibroblasts via Activation of Protease-Activated Receptor-1. Cells. 2021 Oct 30;10(11):2958.

Boon GJAM, Janssen SMJ, Barco S, Bogaard HJ, Ghanima W, Kroft LJM, Meijboom LJ, Ninaber MK, Nossent EJ, Spruit MA, Symersky P, Vliegen HW, Noordegraaf AV, Huisman MV, Siegerink B, Abbink JJ, Klok FA. Efficacy and safety of a 12-week outpatient pulmonary rehabilitation program in Post-PE Syndrome. Thromb Res. 2021 Oct;206:66-75.

Aboyans V, Bauersachs R, Mazzolai L, Brodmann M, Palomares JFR, Debus S, Collet JP, Drexel H, Espinola-Klein C, Lewis BS, Roffi M, Sibbing D, Sillesen H, Stabile E, Schlager O, De Carlo M. Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy. Eur Heart J. 2021 Oct 14;42(39):4013-4024.

Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB. Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J. 2021 Oct 14;42(39):4077-4088.

Zhong X, Wang T, Xie Y, Wang M, Zhang W, Dai L, Lai J, Nie X, He X, Madhusudhan T, Zeng H, Wang H. Activated Protein C Ameliorates Diabetic Cardiomyopathy via Modulating OTUB1/YB-1/MEF2B Axis. Front Cardiovasc Med. 2021 Oct 29;8:758158.

Ebner M, Sentler C, Harjola VP, Bueno H, Lerchbaumer MH, Hasenfuß G, Eckardt KU, Konstantinides SV, Lankeit M. Outcome of patients with different clinical presentations of high-risk pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 Oct 1;10(7):787-796.

Keller K, Schmitt VH, Vosseler M, Brochhausen C, Münzel T, Hobohm L, Espinola-Klein C. Diabetes Mellitus and Its Impact on Patient-Profile and In-Hospital Outcomes in Peripheral Artery Disease. J Clin Med. 2021 Oct 28;10(21):5033.

Fogarty H, Townsend L, Morrin H, Ahmad A, Comerford C, Karampini E, Englert H, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, McGonagle D, Ni Cheallaigh C, Baker RI, Renné T, Ward SE, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Persistent endotheliopathy in the pathogenesis of long COVID syndrome. J Thromb Haemost. 2021 Oct;19(10):2546-2553.

Sebastian T, Barco S, Lichtenberg M, Stahlhoff S, Schlager O, Jalaie H, de Graaf R, Erbel C, Massmann A, Schindewolf M, Kucher N. Twelve-month clinical outcomes of a hybrid oblique self-expanding nitinol stent used for the treatment of post-thrombotic syndrome with common iliac vein compression: The TOPOS study. Vasc Med. 2021 Oct;26(5):569-571.

Haist M, Stege H, Pemler S, Heinz J, Fleischer MI, Graf C, Ruf W, Loquai C, Grabbe S. Anticoagulation with Factor Xa Inhibitors Is Associated with Improved Overall Response and Progression-Free Survival in Patients with Metastatic Malignant Melanoma Receiving Immune Checkpoint Inhibitors-A Retrospective, Real-World Cohort Study. Cancers (Basel). 2021 Oct 12;13(20):5103.

Debus ES, Nehler MR, Govsyeyev N, Bauersachs RM, Anand SS, Patel MR, Fanelli F, Capell WH, Brackin T, Hinterreiter F, Krievins D, Nault P, Piffaretti G, Svetlikov A, Jaeger N, Hess CN, Sillesen HH, Conte M, Mills J, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR, Bonaca MP. Effect of Rivaroxaban and Aspirin in Patients With Peripheral Artery Disease Undergoing Surgical Revascularization: Insights From the VOYAGER PAD Trial. Circulation. 2021 Oct 5;144(14):1104-1116.

Prochaska JH, Arnold N, Falcke A, Kopp S, Schulz A, Buch G, Moll S, Panova-Noeva M, Jünger C, Eggebrecht L, Pfeiffer N, Beutel M, Binder H, Grabbe S, Lackner KJ, Ten Cate-Hoek A, Espinola-Klein C, Münzel T, Wild PS. Chronic venous insufficiency, cardiovascular disease, and mortality: a population study. Eur Heart J. 2021 Oct 21;42(40):4157-4165.

Krantz MJ, Debus SE, Hsia J, Patel MR, Anand SS, Nehler MR, Hess CN, Capell WH, Bracken T, Szarek M, Mátyás L, Krievins DK, Nault P, Stefanov S, Haskell LP, Berkowitz SD, Muehlhofer E, Hiatt WR, Bauersachs RM, Bonaca MP. Low-dose rivaroxaban plus aspirin in older patients with peripheral artery disease undergoing acute limb revascularization: insights from the VOYAGER PAD trial. Eur Heart J. 2021 Oct 14;42(39):4040-4048.

Klok FA, Toenges G, Mavromanoli AC, Barco S, Ageno W, Bouvaist H, Brodmann M, Cuccia C, Couturaud F, Dellas C, Dimopoulos K, Duerschmied D, Empen K, Faggiano P, Ferrari E, Galiè N, Galvani M, Ghuysen A, Giannakoulas G, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Meneveau N, Münzel T, Palazzini M, Petris AO, Piovaccari G, Salvi A, Schellong S, Schmidt KH, Verschuren F, Schmidtmann I, Meyer G, Konstantinides SV; PEITHO-2 investigators. Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial. Lancet Haematol. 2021 Sep;8(9):e627-e636.

Heestermans M, Naudin C, Mailer RK, Konrath S, Klaetschke K, Jämsä A, Frye M, Deppermann C, Pula G, Kuta P, Friese MA, Gelderblom M, Sickmann A, Preston RJS, Nofer JR, Rose-John S, Butler LM, Salomon O, Stavrou EX, Renné T. Identification of the factor XII contact activation site enables sensitive coagulation diagnostics. Nat Commun. 2021 Sep 22;12(1):5596.

Hollerbach A, Müller-Calleja N, Pedrosa D, Canisius A, Sprinzl MF, Falter T, Rossmann H, Bodenstein M, Werner C, Sagoschen I, Münzel T, Schreiner O, Sivanathan V, Reuter M, Niermann J, Galle PR, Teyton L, Ruf W, Lackner KJ. Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19. J Thromb Haemost. 2021 Sep;19(9):2335-2347.

Chu G, Valerio L, van der Wall SJ, Barco S, Konstantinides S, Huisman MV, Klok FA. Tailoring anticoagulant treatment of patients with atrial fibrillation using a novel bleeding risk score. Heart. 2020 Sep 9:heartjnl-2019-316305.

Wasielica-Poslednik J, Hampel U, Ries L, Faysal R, Schulz A, Prochaska JH, Wild PS, Schmidtmann I, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Prevalence of corneal arcus and associated factors in a German population-Results from the Gutenberg Health Study. PLoS One. 2021 Sep 21;16(9):e0255893.

Schmitt VH, Prochaska JH, Föll AS, Schulz A, Keller K, Hahad O, Koeck T, Tröbs SO, Rapp S, Beutel M, Pfeiffer N, Strauch K, Lackner KJ, Münzel T, Wild PS. Galectin-3 for prediction of cardiac function compared to NT-proBNP in individuals with prediabetes and type 2 diabetes mellitus. Sci Rep. 2021 Sep 24;11(1):19012.

Kangro K, Roose E, Joly BS, Sinkovits G, Falter T, von Auer C, Rossmann H, Reti M, Voorberg J, Prohászka Z, Lämmle B, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura. Blood Adv. 2021 Sep 14;5(17):3427-3435.

Kulka HC, Zeller A, Fornaro J, Wuillemin WA, Konstantinides S, Christ M. Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint. Dtsch Arztebl Int. 2021 Sep 17;118(37):618-628.

Boon GJAM, van den Hout WB, Barco S, Bogaard HJ, Delcroix M, Huisman MV, Konstantinides SV, Meijboom LJ, Nossent EJ, Symersky P, Vonk Noordegraaf A, Klok FA. A model for estimating the health economic impact of earlier diagnosis of chronic thromboembolic pulmonary hypertension. ERJ Open Res. 2021 Sep 6;7(3):00719-2020.

Formes H, Bernardes JP, Mann A, Bayer F, Pontarollo G, Kiouptsi K, Schäfer K, Attig S, Nikolova T, Hofmann TG, Schattenberg JM, Todorov H, Gerber S, Rosenstiel P, Bopp T, Sommer F, Reinhardt C. The gut microbiota instructs the hepatic endothelial cell transcriptome. iScience. 2021 Sep 10;24(10):103092.

Reagh JJ, Zheng H, Stolz U, Parry BA, Chang AM, House SL, Giordano NJ, Cohen J, Singer AJ, Francis S, Prochaska JH, Zeserson E, Wild PS, Limkakeng AT Jr, Walters EL, LoVecchio F, Theodoro D, Hollander JE, Kabrhel C, Fermann GJ. Sex-related differences in D-dimer levels for venous thromboembolism screening. Acad Emerg Med. 2021 Aug;28(8):873-881.

Göbel S, Prochaska JH, Tröbs SO, Panova-Noeva M, Espinola-Klein C, Michal M, Lackner KJ, Gori T, Münzel T, Wild PS. Rationale, design and baseline characteristics of the MyoVasc study: A prospective cohort study investigating development and progression of heart failure. Eur J Prev Cardiol. 2021 Aug 9;28(9):1009-1018.

Dahlen B, Schulz A, Göbel S, Tröbs SO, Schwuchow-Thonke S, Spronk HM, Prochaska JH, Arnold N, Lackner KJ, Gori T, Ten Cate H, Münzel T, Wild PS, Panova-Noeva M. The impact of platelet indices on clinical outcome in heart failure: results from the MyoVasc study. ESC Heart Fail. 2021 Aug;8(4):2991-3001.

Kapopara PR, Safikhan NS, Huang JL, Meixner SC, Gonzalez K, Loghmani H, Ruf W, Mast AE, Lei V, Pryzdial ELG, Conway EM. CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models. J Thromb Haemost. 2021 Aug;19(8):1932-1947.

Milstone LM, Jackson C, Becker RC, Camire R, Knabb R, Mann K, Ruf W, Wexler RR, Wood J. Discussion of talks from the symposium: Factor X: From thrombokinase to oral anti-coagulants and beyond. J Thromb Thrombolysis. 2021 Aug;52(2):408-413.

Keller K, Hobohm L, Schmidtmann I, Münzel T, Baldus S, von Bardeleben RS. Centre procedural volume and adverse in-hospital outcomes in patients undergoing percutaneous transvenous edge-to-edge mitral valve repair using MitraClip® in Germany. Eur J Heart Fail. 2021 Aug;23(8):1380-1389.

Keller K, Hobohm L, Schmidtmann I, Münzel T, Baldus S, von Bardeleben RS. Centre procedural volume and adverse in-hospital outcomes in patients undergoing percutaneous transvenous edge-to-edge mitral valve repair using MitraClip® in Germany. Eur J Heart Fail. 2021 Aug;23(8):1380-1389.

Schmitt VH, Billaudelle AM, Schulz A, Keller K, Hahad O, Tröbs SO, Koeck T, Michal M, Schuster AK, Toenges G, Lackner KJ, Prochaska JH, Münzel T, Wild PS. Disturbed Glucose Metabolism and Left Ventricular Geometry in the General Population. J Clin Med. 2021 Aug 27;10(17):3851.

Arnold N, Deiseroth A, Hahad O, Diestelmeier S, Schulz A, Daubenbüchel A, Gori T, Binder H, Pfeiffer N, Prochaska J, Beutel M, Lackner KJ, Münzel T, Wild PS. Domains of Physical Activity in Relation to Stiffness Index in the General Population. J Am Heart Assoc. 2021 Aug 17;10(16):e020930.

Bauersachs R, Gerlach HE, Heinken A, Hoffmann U, Langer F, Noppeney T, Pittrow D, Klotsche J, Rabe E. Management and Outcomes of Patients with Isolated Superficial Vein Thrombosis under Real Life Conditions (INSIGHTS-SVT). Eur J Vasc Endovasc Surg. 2021 Aug;62(2):241-249.

Beckmann L, Rolling CC, Voigtländer M, Mäder J, Klingler F, Schulenkorf A, Lehr C, Bokemeyer C, Ruf W, Langer F. Bacitracin and Rutin Regulate Tissue Factor Production in Inflammatory Monocytes and Acute Myeloid Leukemia Blasts. Cancers (Basel). 2021 Aug 4;13(16):3941.

More P, Bindila L, Wild P, Andrade-Navarro M, Fontaine JF. LipiDisease: associate lipids to diseases using literature mining. Bioinformatics. 2021 Aug 6;37(21):3981–2.

Keller K, Hobohm L, Ostad MA, Göbel S, Lankeit M, Konstantinides S, Münzel T, Wenzel P. Temporal trends and predictors of inhospital death in patients hospitalised for heart failure in Germany. Eur J Prev Cardiol. 2021 Aug 9;28(9):990-997.

Hobohm L, Sebastian T, Valerio L, Mahmoudpour SH, Vatsakis G, Johner F, Keller K, Münzel T, Kucher N, Konstantinides SV, Barco S. Sterblichkeit der Lungenembolie in der DACH-Region [Trends in mortality related to pulmonary embolism in the DACH countries]. Med Klin Intensivmed Notfmed. 2021 Aug 24. German.

Matli B, Schulz A, Koeck T, Falter T, Lotz J, Rossmann H, Pfeiffer N, Beutel M, Münzel T, Strauch K, Wild PS, Lackner KJ. Distribution of HOMA-IR in a population-based cohort and proposal for reference intervals. Clin Chem Lab Med. 2021 Aug 11;59(11):1844-1851.

Fieß A, Ponto KA, Urschitz MS, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Birthweight and its association with retinal vessel equivalents - Results from the population-based German Gutenberg Health Study. Acta Ophthalmol. 2021 Aug;99(5):e773-e774.

Wild J, Distelmeier S, Keil P, Weinmann A, Münzel T, Weinmann-Menke J, Kraus D. Non-bacterial thrombotic endocarditis in a patient with pancreatic carcinoma. Echocardiography. 2021 Aug;38(8):1455-1458.

Mumoli N, Evangelista I, Colombo A, Conte G, Mazzone A, Barco S. Transient perivascular inflammation of the carotid artery (TIPIC) syndrome in a patient with COVID-19.https://pubmed.ncbi.nlm.nih.gov/34000422/ Int J Infect Dis. 2021 Jul;108:126-128.

Wang T, Wu J, Dong W, Wang M, Zhong X, Zhang W, Dai L, Xie Y, Liu Y, He X, Liu W, Madhusudhan T, Zeng H, Wang H. The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation. Int J Biol Sci. 2021 Jul 13;17(12):2984-2999

Schmitt VH, Hobohm L, Münzel T, Wenzel P, Gori T, Keller K. Impact of diabetes mellitus on mortality rates and outcomes in myocardial infarction. Diabetes Metab. 2021 Jul;47(4):101211

Rosner AK, Closs EI, Habermeier A, Gericke A, Binder H, Scharrer I, Pfeiffer N, Ponto KA. Asymmetrisches Dimethylarginin (ADMA) bei retinalen Venenverschlüssen – Ergebnisse aus der Gutenberg-RVO-Studie [Asymmetric dimethylarginine (ADMA) in retinal vein occlusion-Results from the Gutenberg RVO study]. Ophthalmologe. 2021 Jul;118(7):684-69

Schwaegermann MK, Hobohm L, Rausch J, Reuter M, Griemert TF, Sivanathan V, Falter T, Sprinzl MF, Lackner KJ, Galle PR, Konstantinides S, Theobald M, von Auer C. COVID-19 as a Potential Trigger for Immune Thrombotic Thrombocytopenic Purpura and Reason for an Unusual Treatment: A Case Report. Hamostaseologie. 2021 Jul 29.

Mumoli N, Conte G, Cei M, Vitale J, Capra R, Rotiroti G, Porta C, Monolo D, Colombo A, Mazzone A, Kucher N, Konstantinides SV, Dentali F, Barco S. In-hospital fatality and venous thromboembolism during the first and second COVID-19 waves at a center opting for standard-dose thromboprophylaxis. Thromb Res. 2021 Jul;203:82-84.

Michal M, Eggebrecht L, Göbel S, Panova-Noeva M, Nagler M, Arnold N, Lauterbach M, Bickel C, Wiltink J, Beutel ME, Münzel T, Wild PS, Prochaska JH. The relevance of depressive symptoms for the outcome of patients receiving vitamin K antagonists: results from the thrombEVAL cohort study. Eur Heart J Cardiovasc Pharmacother. 2021 Jul 23;7(4):271-279.

Roncon L, Zuin M, Barco S, Zuliani G, Konstantinides SV. Increased interest in acute pulmonary embolism in Italy during the COVID-19 pandemic: a google trends-based analysis. J Thromb Thrombolysis. 2021 Jul;52(1):92-94.

Helmstädter J, Keppeler K, Aust F, Küster L, Frenis K, Filippou K, Vujacic-Mirski K, Tsohataridis S, Kalinovic S, Kröller-Schön S, Oelze M, Bosmann M, Münzel T, Daiber A, Steven S. GLP-1 Analog Liraglutide Improves Vascular Function in Polymicrobial Sepsis by Reduction of Oxidative Stress and Inflammation. Antioxidants (Basel). 2021 Jul 23;10(8):1175.

Bayer F, Ascher S, Kiouptsi K, Kittner JM, Stauber RH, Reinhardt C. Colonization with Altered Schaedler Flora Impacts Leukocyte Adhesion in Mesenteric Ischemia-Reperfusion Injury. Microorganisms. 2021 Jul 27;9(8):1601.

Ten Cate V, Koeck T, Prochaska J, Schulz A, Panova-Noeva M, Rapp S, Eggebrecht L, Lenz M, Glunz J, Sauer M, Ewert R, Halank M, Münzel T, Heitmeier S, Andrade-Navarro MA, Lackner KJ, Konstantinides SV, Leineweber K, Wild PS. A targeted proteomics investigation of the obesity paradox in venous thromboembolism. Blood Adv. 2021 Jul 27;5(14):2909-2918.

Bauersachs RM, Szarek M, Brodmann M, Gudz I, Debus ES, Nehler MR, Anand SS, Patel MR, Hess CN, Capell WH, Rogers K, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR, Bonaca MP; VOYAGER PAD Committees and Investigators. Total Ischemic Event Reduction With Rivaroxaban After Peripheral Arterial Revascularization in the VOYAGER PAD Trial. J Am Coll Cardiol. 2021 Jul 27;78(4):317-326.

Valerio L, Barco S, Jankowski M, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Hoeper MM, Klok FA, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C, Schmidt KH, Seyfarth HJ, Trudzinski F, Wachter R, Wilkens H, Wild PS, Konstantinides SV. Quality of Life 3 and 12 Months Following Acute Pulmonary Embolism: Analysis From a Prospective Multicenter Cohort Study. Chest. 2021 Jun;159(6):2428-2438.

Valerio L, Turatti G, Klok FA, Konstantinides SV, Kucher N, Roncon L, Zuin M, Barco S. Prevalence of pulmonary embolism in 127 945 autopsies performed in cancer patients in the United States between 2003 and 2019. J Thromb Haemost. 2021 Jun;19(6):1591-1593.

Keller K, Hobohm L, Schmitt VH, Engelhardt M, Wenzel P, Post F, Münzel T, Gori T, Friedmann-Bette B. Total numbers and in-hospital mortality of patients with myocardial infarction in Germany during the FIFA soccer world cup 2014. Sci Rep. 2021 Jun 17;11(1):11330.

Lanza E, Mancuso ME, Messana G, Ferrazzi P, Lisi C, Di Micco P, Barco S, Balzarini L, Lodigiani C. Compromised Lung Volume and Hemostatic Abnormalities in COVID-19 Pneumonia: Results from an Observational Study on 510 Consecutive Patients. J Clin Med. 2021 Jun 29;10(13):2894.

Dahlen B, Müller F, Tröbs SO, Heidorn MW, Schulz A, Arnold N, Hermanns MI, Schwuchow-Thonke S, Prochaska JH, Gori T, Ten Cate H, Lackner KJ, Münzel T, Wild PS, Panova-Noeva M. Sex-Specific Relationship Between Parathyroid Hormone and Platelet Indices in Phenotypes of Heart Failure-Results From the MyoVasc Study. Front Cardiovasc Med. 2021 Jun 16;8:682521.

Valerio L, Corsi G, Granziera S, Holm K, Hotz MA, Jankowski M, Konstantinides SV, Kucher N, Nicoletti T, Reinhardt C, Righini C, Sacco C, Trinchero A, Zane F, Pecci A, Barco S. Sex differences in Lemierre syndrome: Individual patient-level analysis. Thromb Res. 2021 Jun;202:36-39.

Barco S, Valerio L, Gallo A, Turatti G, Mahmoudpour SH, Ageno W, Castellucci LA, Cesarman-Maus G, Ddungu H, De Paula EV, Dumantepe M, Goldhaber SZ, Guillermo Esposito MC, Klok FA, Kucher N, McLintock C, Ní Áinle F, Simioni P, Spirk D, Spyropoulos AC, Urano T, Zhai ZG, Hunt BJ, Konstantinides SV. Global reporting of pulmonary embolism-related deaths in the World Health Organization mortality database: Vital registration data from 123 countries. Res Pract Thromb Haemost. 2021 Jun 15;5(5):e12520.

Tarasco E, Bütikofer L, Friedman KD, George JN, Hrachovinova I, Knöbl PN, Matsumoto M, von Krogh AS, Aebi-Huber I, Cermakova Z, Górska-Kosicka M, Jalowiec KA, Largiadèr CR, Prohászka Z, Sinkovits G, Windyga J, Lämmle B, Kremer Hovinga JA. Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura. Blood. 2021 Jun 24;137(25):3563-3575.

Leister H, Luu M, Staudenraus D, Lopez Krol A, Mollenkopf HJ, Sharma A, Schmerer N, Schulte LN, Bertrams W, Schmeck B, Bosmann M, Steinhoff U, Visekruna A. Pro- and Antitumorigenic Capacity of Immunoproteasomes in Shaping the Tumor Microenvironment. Cancer Immunol Res. 2021 Jun;9(6):682-692.

Giustozzi M, Valerio L, Agnelli G, Becattini C, Fronk EM, Klok FA, Konstantinides SV, Vedovati MC, Cohen AT, Barco S. Sex-specific differences in the presentation, clinical course, and quality of life of patients with acute venous thromboembolism according to baseline risk factors. Insights from the PREFER in VTE. Eur J Intern Med. 2021 Jun;88:43-51.

Neulen A, Molitor M, Kosterhon M, Pantel T, Karbach SH, Wenzel P, Gaul T, Ringel F, Thal SC. Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound. https://pubmed.ncbi.nlm.nih.gov/34152320/J Vis Exp. 2021 Jun 3;(172).

Geiß C, Witzler C, Poschet G, Ruf W, Régnier-Vigouroux A. Metabolic and inflammatory reprogramming of macrophages by ONC201 translates in a pro-inflammatory environment even in presence of glioblastoma cells. Eur J Immunol. 2021 May;51(5):1246-1261.

Gerstenberger E, Stoffelns B, Nickels S, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. Incidence of Retinal Detachment in Germany: Results from the Gutenberg Health Study. Ophthalmologica. 2021;244(2):133-140.

Bogucka K, Marini F, Rosigkeit S, Schloeder J, Jonuleit H, David K, Schlackow M, Rajalingam K. ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis. Cancer Gene Ther. 2021 May;28(5):359-374.

Rukoyatkina N, Shpakova V, Sudnitsyna J, Panteleev M, Makhoul S, Gambaryan S, Jurk K. https://pubmed.ncbi.nlm.nih.gov/34065600/Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis. Int J Mol Sci. 2021 May 20;22(10):5405.

Tibubos AN, Otten D, Zöller D, Binder H, Wild PS, Fleischer T, Johar H, Atasoy S, Schulze L, Ladwig KH, Schomerus G, Linkohr B, Grabe HJ, Kruse J, Schmidt CO, Münzel T, König J, Brähler E, Beutel ME. Bidimensional structure and measurement equivalence of the Patient Health Questionnaire-9: sex-sensitive assessment of depressive symptoms in three representative German cohort studies. BMC Psychiatry. 2021 May 5;21(1):238.

Mirshahi A, Schneider A, Latz C, Ponto KA. Perioperative pupil size in low-energy femtosecond laser-assisted cataract surgery. PLoS One. 2021 May 17;16(5):e0251549.

Knopp T, Bieler T, Jung R, Ringen J, Molitor M, Jurda A, Münzel T, Waisman A, Wenzel P, Karbach SH, Wild J. Effects of Dietary Protein Intake on Cutaneous and Systemic Inflammation in Mice with Acute Experimental Psoriasis. https://pubmed.ncbi.nlm.nih.gov/34072973/Nutrients. 2021 May 31;13(6):1897.

Mavromanoli AC, Barco S, Konstantinides SV. Antithrombotics and new interventions for venous thromboembolism: Exploring possibilities beyond factor IIa and factor Xa inhibition. Res Pract Thromb Haemost. 2021 May 18;5(4):10.1002/rth2.12509

Spirk D, Sebastian T, Barco S, Banyai M, Beer JH, Mazzolai L, Baldi T, Aujesky D, Hayoz D, Engelberger RP, Kaeslin T, Korte W, Escher R, Husmann M, Blondon M, Kucher N. Clinical Outcomes of Incidental Venous Thromboembolism in Cancer and Noncancer Patients: The SWIss Venous ThromboEmbolism Registry (SWIVTER). Thromb Haemost. 2021 May;121(5):641-649

Wild J, Jung R, Knopp T, Efentakis P, Benaki D, Grill A, Wegner J, Molitor M, Garlapati V, Rakova N, Markó L, Marton A, Mikros E, Münzel T, Kossmann S, Rauh M, Nakano D, Kitada K, Luft F, Waisman A, Wenzel P, Titze J, Karbach S. Aestivation motifs explain hypertension and muscle mass loss in mice with psoriatic skin barrier defect. Acta Physiol (Oxf). 2021 May;232(1):e13628.

Herken K, Glauner M, Robert SC, Maas M, Zippel S, Nowak-Göttl U, Zieger B, Lahav J, Fender AC, Jurk K, Kehrel BE. Age-Dependent Control of Collagen-Dependent Platelet Responses by Thrombospondin-1-Comparative Analysis of Platelets from Neonates, Children, Adolescents, and Adults. Int J Mol Sci. 2021 May 5;22(9):4883.

Hegewald J, Romero Starke K, Garthus-Niegel S, Schulz A, Nübling M, Latza U, Jankowiak S, Liebers F, Rossnagel K, Riechmann-Wolf M, Letzel S, Arnold N, Beutel M, Gianicolo E, Pfeiffer N, Lackner K, Münzel T, Wild P, Seidler A. Work-life conflict and cardiovascular health: 5-year follow-up of the Gutenberg Health Study. PLoS One. 2021 May 7;16(5):e0251260.

Lerchbaumer MH, Ebner M, Ritter CO, Steimke L, Rogge NIJ, Sentler C, Thielmann A, Hobohm L, Keller K, Lotz J, Hasenfuß G, Wachter R, Hamm B, Konstantinides SV, Aviram G, Lankeit M. Prognostic value of right atrial dilation in patients with pulmonary embolism. ERJ Open Res. 2021 May 24;7(2):00414-2020.

Waas T, Schulz A, Lotz J, Rossmann H, Pfeiffer N, Beutel ME, Schmidtmann I, Münzel T, Wild PS, Lackner KJ. Distribution of estimated glomerular filtration rate and determinants of its age dependent loss in a German population-based study. Sci Rep. 2021 May 13;11(1):10165.

Rodionov RN, Beyer-Westendorf J, Bode-Böger SM, Eggebrecht L, Konstantinides S, Martens-Lobenhoffer J, Nagler M, Prochaska J, Wild P. Homoarginine and methylarginines independently predict long-term outcome in patients presenting with suspicion of venous thromboembolism. Sci Rep. 2021 May 5;11(1):9569.

Hahad O, Arnold N, Prochaska JH, Panova-Noeva M, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Beutel M, Wild PS, Keaney JF Jr, Daiber A, Münzel T. Cigarette Smoking Is Related to Endothelial Dysfunction of Resistance, but Not Conduit Arteries in the General Population-Results From the Gutenberg Health Study. Front Cardiovasc Med. 2021 May 19;8:674622.

Gresele P, Falcinelli E, Bury L, Pecci A, Alessi MC, Borhany M, Heller PG, Santoro C, Cid AR, Orsini S, Fontana P, De Candia E, Podda G, Kannan M, Jurk K, Castaman G, Falaise C, Guglielmini G, Noris P; BAT-VAL Study Investigators. The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology. J Thromb Haemost. 2021 May;19(5):1364-1371.

Ten Cate V, Prochaska JH, Schulz A, Koeck T, Pallares Robles A, Lenz M, Eggebrecht L, Rapp S, Panova-Noeva M, Ghofrani HA, Meyer FJ, Espinola-Klein C, Lackner KJ, Michal M, Schuster AK, Strauch K, Zink AM, Laux V, Heitmeier S, Konstantinides SV, Münzel T, Andrade-Navarro MA, Leineweber K, Wild PS. Protein expression profiling suggests relevance of noncanonical pathways in isolated pulmonary embolism. Blood. 2021 May 13;137(19):2681-2693.

Hobohm L, Schmidt FP, Gori T, Schmidtmann I, Barco S, Münzel T, Lankeit M, Konstantinides SV, Keller K. In-hospital outcomes of catheter-directed thrombolysis in patients with pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 May 11;10(3):258-264.

Hobohm L, Schmidt FP, Gori T, Schmidtmann I, Barco S, Münzel T, Lankeit M, Konstantinides SV, Keller K. In-hospital outcomes of catheter-directed thrombolysis in patients with pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2021 May 11;10(3):258-264.

Geyer M, Keller K, Bachmann K, Born S, Tamm AR, Ruf TF, Kreidel F, Hahad O, Petrescu A, Hell M, Beiras-Fernandez A, Kornberger A, Schulz E, Münzel T, von Bardeleben RS. Concomitant tricuspid regurgitation severity and its secondary reduction determine long-term prognosis after transcatheter mitral valve edge-to-edge repair. Clin Res Cardiol. 2021 May;110(5):676-688.

Ogorodnikov A, Danckwardt S. TRENDseq-A highly multiplexed high throughput RNA 3' end sequencing for mapping alternative polyadenylation. Methods Enzymol. 2021;655:37-72.

Tröbs SO, Prochaska JH, Schwuchow-Thonke S, Schulz A, Müller F, Heidorn MW, Göbel S, Diestelmeier S, Lerma Monteverde J, Lackner KJ, Gori T, Münzel T, Wild PS. Association of Global Longitudinal Strain With Clinical Status and Mortality in Patients With Chronic Heart Failure. JAMA Cardiol. 2021 Apr 1;6(4):448-456.

Ebner M, Pagel CF, Sentler C, Harjola VP, Bueno H, Lerchbaumer MH, Stangl K, Pieske B, Hasenfuß G, Konstantinides SV, Lankeit M. Venous lactate improves the prediction of in-hospital adverse outcomes in normotensive pulmonary embolism. Eur J Intern Med. 2021 Apr;86:25-31

Morla S, Deguchi H, Fernández JA, Ruf W, Brekken RA, Griffin JH. Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids. Blood. 2021 Apr 1;137(13):1839-1842

Guilherme MDS, Nguyen VTT, Reinhardt C, Endres K. Impact of Gut Microbiome Manipulation in 5xFAD Mice on Alzheimer's Disease-Like Pathology. Microorganisms. 2021 Apr 13;9(4):815.

Cuker A, Cataland SR, Coppo P, de la Rubia J, Friedman KD, George JN, Knoebl PN, Kremer Hovinga JA, Lämmle B, Matsumoto M, Pavenski K, Peyvandi F, Sakai K, Sarode R, Thomas MR, Tomiyama Y, Veyradier A, Westwood JP, Scully M. Redefining outcomes in immune TTP: an international working group consensus report. Blood. 2021 Apr 8;137(14):1855-1861.

Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller-Schön S, Bayo Jimenez MT, Hahad O, Oelze M, Jiang S, Wenzel P, Sommer CJ, Frauenknecht KBM, Waisman A, Gericke A, Daiber A, Münzel T, Steven S. Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects. Basic Res Cardiol. 2021 Apr 30;116(1):31

Neubauer K, Jurk K, Petermann V, Kumm E, Zieger B. Impaired Platelet Function in Sept8-Deficient Mice In Vitro. Thromb Haemost. 2021 Apr;121(4):484-494

Keller K, Münzel T, Hobohm L, Ostad MA. Predictive value of the Kuijer score for bleeding and other adverse in-hospital events in patients with venous thromboembolism. Int J Cardiol. 2021 Apr 15;329:179-184.

Fieß A, Lamparter J, Raum P, Peto T, Ponto KA, Nickels S, Münzel T, Wild PS, Beutel ME, Urschitz MS, Lackner KJ, Pfeiffer N, Schuster AK. Birth Weight and Diabetic Retinopathy: Results From the Population-Based Gutenberg Health Study (GHS). Ophthalmic Epidemiol. 2021 Apr;28(2):122-130.

Müller-Calleja N, Hollerbach A, Royce J, Ritter S, Pedrosa D, Madhusudhan T, Teifel S, Meineck M, Häuser F, Canisius A, Nguyen TS, Braun J, Bruns K, Etzold A, Zechner U, Strand S, Radsak M, Strand D, Gu JM, Weinmann-Menke J, Esmon CT, Teyton L, Lackner KJ, Ruf W. Lipid presentation by the protein C receptor links coagulation with autoimmunity. Science. 2021 Mar 12;371(6534):eabc0956.

Triantafyllias K, Cavagna L, Klonowski A, Drott U, Fiehn C, Wendel S, Bergner R, de Blasi M, Voll RE, Baulmann J, Konstantinides S, Galle PR, Schwarting A. Possible misclassification of cardiovascular risk by SCORE in antisynthetase syndrome: results of the pilot multicenter study RI.CAR.D.A. Rheumatology (Oxford). 2021 Mar 2;60(3):1300-1312.

Valerio L, Zane F, Sacco C, Granziera S, Nicoletti T, Russo M, Corsi G, Holm K, Hotz MA, Righini C, Karkos PD, Mahmoudpour SH, Kucher N, Verhamme P, Di Nisio M, Centor RM, Konstantinides SV, Pecci A, Barco S. Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases. J Intern Med. 2021 Mar;289(3):325-339.

Wejbera M, Wölfling K, Dreier M, Michal M, Brähler E, Wiltink J, Schulz A, Wild PS, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. Risk factors, physical and mental health burden of male and female pathological gamblers in the German general population aged 40-80. BMC Psychiatry. 2021 Mar 4;21(1):123.

Rudi WS, Molitor M, Garlapati V, Finger S, Wild J, Münzel T, Karbach SH, Wenzel P. https://pubmed.ncbi.nlm.nih.gov/33807982/ACE Inhibition Modulates Myeloid Hematopoiesis after Acute Myocardial Infarction and Reduces Cardiac and Vascular Inflammation in Ischemic Heart Failure. Antioxidants (Basel). 2021 Mar 5;10(3):396.

Zierold S, Buschmann K, Gachkar S, Bochenek ML, Velmeden D, Hobohm L, Vahl CF, Schäfer K. Brain-Derived Neurotrophic Factor Expression and Signaling in Different Perivascular Adipose Tissue Depots of Patients With Coronary Artery Disease. J Am Heart Assoc. 2021 Mar 16;10(6):e018322.

Shahneh F, Grill A, Klein M, Frauhammer F, Bopp T, Schäfer K, Raker VK, Becker C. Specialized regulatory T cells control venous blood clot resolution through SPARC. Blood. 2021 Mar 18;137(11):1517-1526.

Settelmeier S, Hochadel M, Giannitsis E, Konstantinides S, Voigtländer T, Schmitt C, Haude M, Kerber S, Mudra H, Gonska BD, Senges J, Breuckmann F, Münzel T. Management of Pulmonary Embolism: Results from the German Chest Pain Unit Registry. Cardiology. 2021;146(3):304-310.

Regen T, Isaac S, Amorim A, Núñez NG, Hauptmann J, Shanmugavadivu A, Klein M, Sankowski R, Mufazalov IA, Yogev N, Huppert J, Wanke F, Witting M, Grill A, Gálvez EJC, Nikolaev A, Blanfeld M, Prinz I, Schmitt-Kopplin P, Strowig T, Reinhardt C, Prinz M, Bopp T, Becher B, Ubeda C, Waisman A. IL-17 controls central nervous system autoimmunity through the intestinal microbiome. Sci Immunol. 2021 Feb 5;6(56):eaaz6563.

van Paridon PCS, Panova-Noeva M, van Oerle R, Schulz A, Prochaska JH, Arnold N, Schmidtmann I, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Hackeng TM, Ten Cate H, Wild PS, Spronk HMH. Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample. Thromb Haemost. 2021 Feb;121(2):174-181.

Falter T, Rossmann H, Menge P, Goetje J, Groenwoldt S, Weinmann A, Sivanathan V, Schulz A, Lemmermann NAW, Danckwardt S, Lackner KJ, Galle PR, Scharrer I, Lämmle B, Sprinzl MF. No Evidence for Classic Thrombotic Microangiopathy in COVID-19. J Clin Med. 2021 Feb 9;10(4):671.

Arnold N, Merzenich H, Wingerter A, Schulz A, Schneider A, Prochaska JH, Göbel S, Neu MA, Henninger N, Panova-Noeva M, Eckerle S, Spix C, Schmidtmann I, Lackner KJ, Beutel ME, Pfeiffer N, Münzel T, Faber J, Wild PS. Promotion of Arterial Stiffness by Childhood Cancer and Its Characteristics in Adult Long-Term Survivors. J Am Heart Assoc. 2021 Feb;10(5):e015609

Velásquez Pereira LC, Roose E, Graça NAG, Sinkovits G, Kangro K, Joly BS, Tellier E, Kaplanski G, Falter T, Von Auer C, Rossmann H, Feys HB, Reti M, Prohászka Z, Lämmle B, Voorberg J, Coppo P, Veyradier A, De Meyer SF, Männik A, Vanhoorelbeke K. Immunogenic hotspots in the spacer domain of ADAMTS13 in immune-mediated thrombotic thrombocytopenic purpura. J Thromb Haemost. 2021 Feb;19(2):478-488

Rashidi F, Barco S, Kamangar F, Heresi GA, Emadi A, Kaymaz C, Jansa P, Reis A, Rashidi A, Taghizadieh A, Rezaeifar P, Moghimi M, Ghodrati S, Mozafari A, Foumani AA, Tahamtan O, Rafiee E, Abbaspour Z, Khodadadi K, Alamdari G, Boodaghi Y, Rezaei M, Muhammadi MJ, Abbasi M, Movaseghi F, Koohi A, Shakourzad L, Ebrahimi F, Radvar S, Amoozadeh M, Fereidooni F, Naseari H, Movalled K, Ghorbani O, Ansarin K. Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: Prospective results from a multi-center study. Thromb Res. 2021 Feb;198:135-138

Hampel U, Wasielica-Poslednik J, Ries L, Faysal R, Schulz A, Nickels S, Wild PS, Schmidtmann I, Münzel T, Beutel ME, Lackner KJ, Pfeiffer N, Schuster AK. Prevalence of pterygium and identification of associated factors in a German population - results from the Gutenberg Health Study. Acta Ophthalmol. 2021 Feb;99(1):e130-e131.

Di Pilla M, Barco S, Sacco C, Barosi G, Lodigiani C. Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis - case report and systematic review of dabigatran use. Vasa. 2021 Feb;50(2):151-156

Barco S, Schmidtmann I, Ageno W, Anušić T, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jiménez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Lankeit M, Manolis A, Meyer A, Münzel T, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Valerio L, Westerweel PE, Wild PS, Konstantinides SV; HoT-PE Investigators; HoT-PE Trial Investigators are:. Survival and quality of life after early discharge in low-risk pulmonary embolism. Eur Respir J. 2021 Feb 4;57(2):2002368

Neulen A, Molitor M, Kosterhon M, Pantel T, Holzbach E, Rudi WS, Karbach SH, Wenzel P, Ringel F, Thal SC. Correlation of cardiac function and cerebral perfusion in a murine model of subarachnoid hemorrhage. Sci Rep. 2021 Feb 8;11(1):3317.

Alwan F, Vendramin C, Budde U, Liesner R, Taylor A, Thomas M, Lämmle B, Scully M. Assessing thrombogenesis and treatment response in congenital thrombotic thrombocytopenic purpura. EJHaem. 2021 Feb 28;2(2):188-195.

Wendt R, Kalbitz S, Otto F, Falter T, Beige J, Rossmann H, Lämmle B. Diagnosis of Hereditary TTP Caused by Homozygosity for a Rare Complex ADAMTS13 Allele After Salmonella Infection in a 43-Year-Old Asylum Seeker. Front Med (Lausanne). 2021 Feb 26;8:639441.

Schwuchow-Thonke S, Göbel S, Emrich T, Schmitt VH, Fueting F, Klank C, Escher F, Schultheiss HP, Münzel T, Keller K, Wenzel P. Increased C reactive protein, cardiac troponin I and GLS are associated with myocardial inflammation in patients with non-ischemic heart failure. Sci Rep. 2021 Feb 4;11(1):3008.

Machado FVC, Meys R, Delbressine JM, Vaes AW, Goërtz YMJ, van Herck M, Houben-Wilke S, Boon GJAM, Barco S, Burtin C, van 't Hul A, Posthuma R, Franssen FME, Spies Y, Vijlbrief H, Pitta F, Rezek SA, Janssen DJA, Siegerink B, Klok FA, Spruit MA. Construct validity of the Post-COVID-19 Functional Status Scale in adult subjects with COVID-19. Health Qual Life Outcomes. 2021 Feb 3;19(1):40.

Otten D, Tibubos AN, Schomerus G, Brähler E, Binder H, Kruse J, Ladwig KH, Wild PS, Grabe HJ, Beutel ME. Similarities and Differences of Mental Health in Women and Men: A Systematic Review of Findings in Three Large German Cohorts. Front Public Health. 2021 Feb 5;9:553071.

Marini F, Scherzinger D, Danckwardt S. TREND-DB-a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation. Nucleic Acids Res. 2021 Jan 8;49(D1):D243-D253.

Falter T, Böschen S, Schepers M, Beutel M, Lackner K, Scharrer I, Lämmle B. Influence of Personality, Resilience and Life Conditions on Depression and Anxiety in 104 Patients Having Survived Acute Autoimmune Thrombotic Thrombocytopenic Purpura. J Clin Med. 2021 Jan 19;10(2):365.

Molitor M, Rudi WS, Garlapati V, Finger S, Schüler R, Kossmann S, Lagrange J, Nguyen TS, Wild J, Knopp T, Karbach SH, Knorr M, Ruf W, Münzel T, Wenzel P. Nox2+ myeloid cells drive vascular inflammation and endothelial dysfunction in heart failure after myocardial infarction via angiotensin II receptor type 1. Cardiovasc Res. 2021 Jan 1;117(1):162-177.

Eggebrecht L, Ludolph P, Göbel S, Panova-Noeva M, Arnold N, Nagler M, Bickel C, Lauterbach M, Hardt R, Cate HT, Lackner KJ, Espinola-Klein C, Münzel T, Prochaska JH, Wild PS. Cost saving analysis of specialized, eHealth-based management of patients receiving oral anticoagulation therapy: Results from the thrombEVAL study. Sci Rep. 2021 Jan 28;11(1):2577.

Mehling R, Schwenck J, Lemberg C, Trautwein C, Zizmare L, Kramer D, Müller A, Fehrenbacher B, Gonzalez-Menendez I, Quintanilla-Martinez L, Schröder K, Brandes RP, Schaller M, Ruf W, Eichner M, Ghoreschi K, Röcken M, Pichler BJ, Kneilling M. Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions. Theranostics. 2021 Jan 1;11(2):470-490.

Hahad O, Wild PS, Prochaska JH, Schulz A, Lackner KJ, Pfeiffer N, Schmidtmann I, Michal M, Beutel M, Daiber A, Münzel T. Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality? Clin Res Cardiol. 2021 Jan;110(1):29-39.

Ernst M, Brähler E, Otten D, Werner AM, Tibubos AN, Reiner I, Wicke F, Wiltink J, Michal M, Nagler M, Münzel T, Wild PS, König J, Pfeiffer N, Borta A, Lackner KJ, Beutel ME. Inflammation predicts new onset of depression in men, but not in women within a prospective, representative community cohort. Sci Rep. 2021 Jan 26;11(1):2271.

Ernst M, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. Loneliness predicts suicidal ideation and anxiety symptoms in long-term childhood cancer survivors. Int J Clin Health Psychol. 2021 Jan-Apr;21(1):100201.

Fieß A, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Urschitz MS, Lackner KJ, Pfeiffer N, Schuster AK. The relationship of ocular geometry with refractive error in normal and low birth weight adults. J Optom. 2021 Jan-Mar;14(1):50-57.

Adenaeuer A, Ezigbo ED, Fawzy Nazir H, Barco S, Trinchero A, Laubert-Reh D, Strauch K, Wild PS, Lackner KJ, Lämmle B, Rossmann H. c.451dupT in KLKB1 is common in Nigerians, confirming a higher prevalence of severe prekallikrein deficiency in Africans compared to Europeans. J Thromb Haemost. 2021 Jan;19(1):147-152.

Valerio L, Ferrazzi P, Sacco C, Ruf W, Kucher N, Konstantinides SV, Barco S, Lodigiani C; Humanitas COVID-19 Task Force. Course of D-Dimer and C-Reactive Protein Levels in Survivors and Nonsurvivors with COVID-19 Pneumonia: A Retrospective Analysis of 577 Patients. Thromb Haemost. 2021 Jan;121(1):98-101.

Lommatzsch M, Rabe KF, Taube C, Joest M, Kreuter M, Wirtz H, Blum TG, Kolditz M, Geerdes-Fenge H, Otto-Knapp R, Häcker B, Schaberg T, Ringshausen FC, Vogelmeier CF, Reinmuth N, Reck M, Gottlieb J, Konstantinides S, Meyer FJ, Worth H, Windisch W, Welte T, Bauer T. Risikoabschätzung bei Patienten mit chronischen Atemwegs- und Lungenerkrankungen im Rahmen der SARS-CoV-2-Pandemie [Risk Assessment for Patients with Chronic Respiratory and Pulmonary Conditions in the Context of the SARS-CoV-2 Pandemic - Statement of the German Respiratory Society (DGP) with the Support of the German Association of Respiratory Physicians (BdP)]. Pneumologie. 2021 Jan;75(1):19-30.

Barco S, Valerio L, Ageno W, Cohen AT, Goldhaber SZ, Hunt BJ, Iorio A, Jimenez D, Klok FA, Kucher N, Mahmoudpour SH, Middeldorp S, Münzel T, Tagalakis V, Wendelboe AM, Konstantinides SV. Age-sex specific pulmonary embolism-related mortality in the USA and Canada, 2000-18: an analysis of the WHO Mortality Database and of the CDC Multiple Cause of Death database. Lancet Respir Med. 2021 Jan;9(1):33-42.

Reviews 2021

Valerio L, Pleming W, Pecci A, Barco S. Management of Lemierre Syndrome. Minerva Med. 2021 Dec;112(6):726-739.

Sharma A, Kontodimas K, Bosmann M. The MAVS Immune Recognition Pathway in Viral Infection and Sepsis. Antioxid Redox Signal. 2021 Dec;35(16):1376-1392.

Pruszczyk P, Skowrońska M, Ciurzyński M, Kurnicka K, Lankeit M, Konstantinides S. Assessment of pulmonary embolism severity and the risk of early death. Pol Arch Intern Med. 2021 Dec 22;131(12):16134.

Hobohm L, Lankeit M. Lungenembolie [Pulmonary Embolism]. Pneumologie. 2021 Oct;75(10):800-818

Jonas RA, Rokohl AC, Kakkassery V, Ponto KA, Lohneis P, Heindl LM. Diagnostik von benignen und malignen Tumoren der Orbita [Diagnostics of benign and malignant tumors of the orbit]. Ophthalmologe. 2021 Oct;118(10):987-994.

Ponto KA, Brockmann MA, Koutsimpelas D, Heider J, Ringel FA, Heindl LM, Kakassery V. Exzisionale Chirurgie orbitaler Tumoren [Excisional surgery of orbital tumors]. Ophthalmologe. 2021 Oct;118(10):995-1003.

Ponto KA, Heindl LM, Kakkassery V. SOP Versorgung von orbitalen Tumoren [SOP best care of orbital tumors]. Ophthalmologe. 2021 Oct;118(10):1012.

Jurk K. Thrombozytopenie [Thrombocytopenia]. MMW Fortschr Med. 2021 Oct;163(17):60-62.

Huang J, Zhang P, Solari FA, Sickmann A, Garcia A, Jurk K, Heemskerk JWM. Molecular Proteomics and Signalling of Human Platelets in Health and Disease. Int J Mol Sci. 2021 Sep 13;22(18):9860.

Kulka HC, Zeller A, Fornaro J, Wuillemin WA, Konstantinides S, Christ M. Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint. Dtsch Arztebl Int. 2021 Sep 17;118(37):618-628.

Ruf W. Roles of factor Xa beyond coagulation. J Thromb Thrombolysis. 2021 Aug;52(2):391-396. doi: 10.1007/s11239-021-02458-8.

Rivera-Lebron B, Bauersachs R. Direct oral anticoagulants for the treatment of pulmonary embolism in patients with renal impairment. Thromb Res. 2021 Aug;204:101-107.

Zifkos K, Dubois C, Schäfer K. Extracellular Vesicles and Thrombosis: Update on the Clinical and Experimental Evidence. Int J Mol Sci. 2021 Aug 27;22(17):9317.

Herster F, Karbach S, Chatterjee M, Weber ANR. Platelets: Underestimated Regulators of Autoinflammation in Psoriasis. J Invest Dermatol. 2021 Jun;141(6):1395-1403.

Shiravand Y, Walter U, Jurk K. Fine-Tuning of Platelet Responses by Serine/Threonine Protein Kinases and Phosphatases-Just the Beginning. Hamostaseologie. 2021 Jun;41(3):206-216.

Baidildinova G, Nagy M, Jurk K, Wild PS, Ten Cate H, van der Meijden PEJ. Soluble Platelet Release Factors as Biomarkers for Cardiovascular Disease. Front Cardiovasc Med. 2021 Jun 21;8:684920.

Bayer F, Dremova O, Khuu MP, Mammadova K, Pontarollo G, Kiouptsi K, Soshnikova N, May-Simera HL, Endres K, Reinhardt C. The Interplay between Nutrition, Innate Immunity, and the Commensal Microbiota in Adaptive Intestinal Morphogenesis. Nutrients. 2021 Jun 26;13(7):2198.

Lagrange J, Lacolley P, Wahl D, Peyrin-Biroulet L, Regnault V. Shedding Light on Hemostasis in Patients With Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2021 Jun;19(6):1088-1097.e6.

Sharma A, Kontodimas K, Bosmann M. Nanomedicine: A Diagnostic and Therapeutic Approach to COVID-19. Front Med (Lausanne). 2021 Jun 4;8:648005.

Ozsu S, Gunay E, Konstantinides SV. A review of venous thromboembolism in COVID-19: A clinical perspective. Clin Respir J. 2021 May;15(5):506-512.

Talasaz AH, Sadeghipour P, Kakavand H, Aghakouchakzadeh M, Kordzadeh-Kermani E, Van Tassell BW, Gheymati A, Ariannejad H, Hosseini SH, Jamalkhani S, Sholzberg M, Monreal M, Jimenez D, Piazza G, Parikh SA, Kirtane AJ, Eikelboom JW, Connors JM, Hunt BJ, Konstantinides SV, Cushman M, Weitz JI, Stone GW, Krumholz HM, Lip GYH, Goldhaber SZ, Bikdeli B. Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 Apr 20;77(15):1903-1921.

Weissler EH, Aboyans V, Bauersachs R, Brodmann M, Nikol S, Debus S, Patel MR, Jones WS. The Role for Combined Antithrombotic Therapy With Platelet and Coagulation Inhibition After Lower Extremity Revascularization. JACC Cardiovasc Interv. 2021 Apr 12;14(7):796-802

Karnati S, Seimetz M, Kleefeldt F, Sonawane A, Madhusudhan T, Bachhuka A, Kosanovic D, Weissmann N, Krüger K, Ergün S. Chronic Obstructive Pulmonary Disease and the Cardiovascular System: Vascular Repair and Regeneration as a Therapeutic Target. Front Cardiovasc Med. 2021 Apr 12;8:649512

Diana T, Ponto KA, Kahaly GJ. Thyrotropin receptor antibodies and Graves' orbitopathy. J Endocrinol Invest. 2021 Apr;44(4):703-712

Jurk K, Shiravand Y. Platelet Phenotyping and Function Testing in Thrombocytopenia. J Clin Med. 2021 Mar 7;10(5):1114.

Wild J, Wenzel P. Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension. J Mol Med (Berl). 2021 Mar;99(3):315-326.

Jung R, Wild J, Ringen J, Karbach S, Wenzel P. Innate Immune Mechanisms of Arterial Hypertension and Autoimmune Disease. Am J Hypertens. 2021 Mar 11;34(2):143-153.

Squiccimarro E, Jiritano F, Serraino GF, Ten Cate H, Paparella D, Lorusso R. Quantitative and Qualitative Platelet Derangements in Cardiac Surgery and Extracorporeal Life Support. J Clin Med. 2021 Feb 6;10(4):615.

Nourse J, Danckwardt S. A novel rationale for targeting FXI: Insights from the hemostatic microRNA targetome for emerging anticoagulant strategies. Pharmacol Ther. 2021 Feb;218:107676.

Di Pilla M, Barco S, Sacco C, Barosi G, Lodigiani C. Acute limb ischemia in a patient with pre-fibrotic myelofibrosis complicated by heparin-induced thrombocytopenia and thrombosis - case report and systematic review of dabigatran use. Vasa. 2021 Feb;50(2):151-156.

Sukumar S, Lämmle B, Cataland SR. Thrombotic Thrombocytopenic Purpura: Pathophysiology, Diagnosis, and Management. J Clin Med. 2021 Feb 2;10(3):536.

Kakkos SK, Gohel M, Baekgaard N, Bauersachs R, Bellmunt-Montoya S, Black SA, Ten Cate-Hoek AJ, Elalamy I, Enzmann FK, Geroulakos G, Gottsäter A, Hunt BJ, Mansilha A, Nicolaides AN, Sandset PM, Stansby G, Esvs Guidelines Committee, de Borst GJ, Bastos Gonçalves F, Chakfé N, Hinchliffe R, Kolh P, Koncar I, Lindholt JS, Tulamo R, Twine CP, Vermassen F, Wanhainen A, Document Reviewers, De Maeseneer MG, Comerota AJ, Gloviczki P, Kruip MJHA, Monreal M, Prandoni P, Vega de Ceniga M. Editor's Choice - European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis. Eur J Vasc Endovasc Surg. 2021 Jan;61(1):9-82.

Editorials und Fachbeiträge 2021

Konstantinides S, Mavromanoli A, Hobohm L. Diagnostik und Therapie der Lungenembolie [Diagnosis and treatment of pulmonary embolism]. Herz. 2021 Dec;46(6):589-604.

Ruggeri ZM, Ruf W. Is VITT really a HIT. Nat Immunol. 2021 Nov;22(11):1352-1353.

Barco S, Valerio L. Management of acute pulmonary embolism: towards a (truly) global reach. Eur Respir J. 2021 Oct 28;58(4):2101055.

Valerio L, Pleming W, Barco S. Re: Internal Jugular Vein and Cerebral Venous Sinus Infective Thrombophlebitis Detected With 99mTc-HMPAO White Blood Cell Scintigraphy. Clin Nucl Med. 2021 Oct 1;46(10):858-859.

Eichinger S, Morange PE, Cattaneo M, Fretigny M, Rauch A, van Hylckama Vlieg A, Trégouët DA, Ruf W, Levi M, Páramo JA, van der Poll T, Kyrle PA, Garagiola I, Peyvandi F. The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders. Hemasphere. 2021 Sep 10;5(10):e643.

Lämmle B, Rossmann H. Invited commentary to: ADAMTS13 deficiency is associated with abnormal distribution of von Willebrand factor multimers in patients with COVID-19 by Tiffany Pascreau et al. Letter to the Editors-in-Chief, Thrombosis Research. Thromb Res. 2021 Aug;204:141-142.

Ten Cate H, Lämmle B. Special Issue: "The Latest Clinical Advances in Thrombocytopenia". J Clin Med. 2021 Aug 5;10(16):3463.

Ten Cate H. Surviving Covid-19 with Heparin? N Engl J Med. 2021 Aug 26;385(9):845-846. doi: 10.1056/NEJMe2111151.

Barco S, Klok FA. D-dimer testing after anticoagulant discontinuation to predict recurrent venous thromboembolism. Eur J Intern Med. 2021 Jul;89:25-26.

Kakkos SK, Gohel M, Bauersachs R. Re "Is Management of Major Bleeding in Patients Taking Anticoagulants Restricted to Reversal Strategies?". Eur J Vasc Endovasc Surg. 2021 Jul;62(1):142-143.

Konstantinides SV. Thrombotic complications of vaccination against SARS-CoV-2: what pharmacovigilance reports tell us - and what they don't. Eur Respir J. 2021 Jul 1;58(1):2101111.

Prochaska JH, Müller F, Wild PS. Impact of diesel exposure on human health: the saga continues …. Eur J Prev Cardiol. 2020 Apr 9:2047487320915335.

Lämmle B. Endothelial Dysfunction, Atherosclerosis, and Increase of Von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine. Thromb Haemost. 2021 May;121(5):552.

Ten Cate H. Thrombosis: Grand Challenges Ahead! Front Cardiovasc Med. 2021 May 4;8:637005.

Ten Cate H. Colorectal cancer and cardiovascular disease: A thrombo-inflammatory link? Eur J Intern Med. 2021 May;87:15-17.

Barco S, Adenaeuer A, Trinchero A, Falter T, Lackner KJ, Lämmle B, Rossmann H. Comment on "Worldwide Distribution of PK Deficiency: the Defect Seems Mainly Concentrated in West African Countries and the United States". Mediterr J Hematol Infect Dis. 2021 Mar 1;13(1):e2021027.

Barco S, Bates SM, Versteeg HH, Klok FA. COVID-19 in thrombosis research: An editorial perspective. Thromb Res. 2021 May;201:147-150.

Bosmann M. Complement control for COVID-19. https://pubmed.ncbi.nlm.nih.gov/34035117/Sci Immunol. 2021 May 25;6(59):eabj1014.

Pilarczyk K., El Mokhtari N. E., Fleischmann T., Haake N., Konstantinides S. V. Diagnostics and Treatment of acute Pulmonary Embolism. Summary of the current 2019 Guidelines of the European Society of Cardiology. NOTFALL & RETTUNGSMEDIZIN. Feb. 2021

Valerio L, Barco S. Reader comments: Chest surgery in Lemierre syndrome. Proc (Bayl Univ Med Cent). 2021 Jan 11;34(2):336.

Schäfer K, Wenzel P. When big eaters stop feasting: loss of metabolic control in macrophages exacerbates hypertension in obesity. https://pubmed.ncbi.nlm.nih.gov/32298411/Cardiovasc Res. 2021 Jan 21;117(2):351-353.

Gallo A, Valerio L, Barco S. The 2019 European guidelines on pulmonary embolism illustrated with the aid of an exemplary case report. Eur Heart J Case Rep. 2021 Jan 4;5(2):ytaa542.

Ascher S, Wilms E, Pontarollo G, Kiouptsi K, Malinarich F, Kittner JM, Bosmann M, Jurk K, Reinhardt C. Response by Ascher et al to Letter Regarding Article, "Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury". Arterioscler Thromb Vasc Biol. 2021 Jan;41(1):e74-e75.

Originalartikel 2020

Göbel S, Schwuchow-Thonke S, Jansen T, Karbach S, Emrich T, Gori T, Knies F, Schulz E, Münzel T, Keller K, Wenzel P. Safety of transradial and transfemoral left ventricular compared with transfemoral right ventricular endomyocardial biopsy. ESC Heart Fail. 2020 Dec;7(6):4015-4023

Roncon L, Zuin M, Barco S, Valerio L, Zuliani G, Zonzin P, Konstantinides SV. Incidence of acute pulmonary embolism in COVID-19 patients: Systematic review and meta-analysis.https://pubmed.ncbi.nlm.nih.gov/32958372/ Eur J Intern Med. 2020 Dec;82:29-37

Kyselova A, Elgheznawy A, Wittig I, Heidler J, Mann AW, Ruf W, Fleming I, Randriamboavonjy V. Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes. Basic Res Cardiol. 2020 Dec 1;115(6):75

Keller K, Hobohm L, Münzel T, Lankeit M, Ostad MA. Impact of pulmonary embolism on in-hospital mortality of patients with ischemic stroke.https://pubmed.ncbi.nlm.nih.gov/33059297/ J Neurol Sci. 2020 Dec 15;419:117174

Hobohm L, Becattini C, Ebner M, Lerchbaumer MH, Casazza F, Hasenfuß G, Konstantinides SV, Lankeit M. Definition of tachycardia for risk stratification of pulmonary embolism. Eur J Intern Med. 2020 Dec;82:76-82

Mahmoudpour SH, Valerio L, Douxfils J, Mahan CE, Jankowski M, Quitzau K, Konstantinides SV, Barco S. Potential Drug Interactions between Recombinant Interleukin-2 and Direct Oral Anticoagulants: Indirect Evidence from In Vivo Animal Studies. Hamostaseologie. 2020 Dec;40(5):679-686

Lenz M, Schulz A, Koeck T, Rapp S, Nagler M, Sauer M, Eggebrecht L, Ten Cate V, Panova-Noeva M, Prochaska JH, Lackner KJ, Münzel T, Leineweber K, Wild PS, Andrade-Navarro MA. Missing value imputation in proximity extension assay-based targeted proteomics data. PLoS One. 2020 Dec 14;15(12):e0243487

Zimmer N, Krebs FK, Zimmer S, Mitzel-Rink H, Kumm EJ, Jurk K, Grabbe S, Loquai C, Tuettenberg A. Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis. Cancers (Basel). 2020 Dec 5;12(12):3653

Blessing R, Ahoopai M, Geyer M, Brandt M, Zeiher AM, Münzel T, Wenzel P, Gori T, Dimitriadis Z. The Bioengineered Combo Dual-Therapy CD34 Antibody-Covered Sirolimus-Eluting Coronary Stent in Patients with Chronic Total Occlusion Evaluated by Clinical Outcome and Optical Coherence Tomography Imaging Analysis. J Clin Med. 2020 Dec 28;10(1):80

Ebner M, Guddat N, Keller K, Merten MC, Lerchbaumer MH, Hasenfuß G, Konstantinides SV, Lankeit M. High-sensitivity troponin I for risk stratification in normotensive pulmonary embolism. ERJ Open Res. 2020 Dec 21;6(4):00625-2020

Marini F, Linke J, Binder H. ideal: an R/Bioconductor package for interactive differential expression analysis. BMC Bioinformatics. 2020 Dec 9;21(1):565

Beutel ME, Tibubos AN, Michal M, Wiltink J, Otten D, Werner A, Wild PS, Münzel T, Lackner KJ, Pfeiffer N, König J, Brähler E. Psychosomatische Medizin in der Gutenberg- Gesundheitsstudie (GHS) – Fragestellungen, Messverfahren, ausgewählte Ergebnisse [Psychosomatic medicine in the Gutenberg Health Study (GHS) - research questions, measurement instruments, selected results]. Z Psychosom Med Psychother. 2020 Dec;66(4):355-375

Gaonkar KS, Marini F, Rathi KS, Jain P, Zhu Y, Chimicles NA, Brown MA, Naqvi AS, Zhang B, Storm PB, Maris JM, Raman P, Resnick AC, Strauch K, Taroni JN, Rokita JL. annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions. BMC Bioinformatics. 2020 Dec 14;21(1):577

Geyer M, Keller K, Sotiriou E, Tamm AR, Ruf TF, Kreidel F, Beiras-Fernandez A, Gori T, Schulz E, Münzel T, von Bardeleben RS. Association of transcatheter direct mitral annuloplasty with acute anatomic, haemodynamic, and clinical outcomes in severe mitral valve regurgitation. ESC Heart Fail. 2020 Dec;7(6):3336-3344

Adamopoulos S, Miliopoulos D, Karavidas A, Nikolaou M, Lazaros G, Gkouziouta A, Manginas A, Sevastos G, Karvounis H, Karamitsos TD, Hahalis G, Leopoulou M, Grigoriou K, Balta D, Avgeropoulou CC, Kasiakogias A, Mantas I, Daskalopoulos N, Varvarousis D, Parthenakis FI, Patrianakos AP, Patsilinakos S, Karanikas S, Konstantinides SV, Tziakas DN, Kouvelas N, Ntoliou P, Manolis AJ, Tsinivizov P, Iliodromitis EK, Vrettou AR, Kakouros SN, Douras A, Mpaka N, Makridis P, Karapatsoudi E, Papoulidis N, Sideris A, Parissis JT, Triposkiadis F, Trikas A, Filippatos G. HEllenic Registry on Myocarditis SyndromES on behalf of Hellenic Heart Failure Association: The HERMES-HF Registry. ESC Heart Fail. 2020 Dec;7(6):3676-3684

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 Dec 3;27(6):962-973.e7

Obradovic S, Dzudovic B, Subotic B, Matijasevic J, Mladenovic Z, Bokan A, Trobok J, Pekovic S, Salinger-Martinovic S, Jovanovic L, Kos L, Kovacevic-Preradovic T, Nikolic M, Miloradovic V, Kovacevic-Kuzmanovic A, Zec N, Markovic-Nikolic N, Srdanovic I, Gluvic Z, Kafedzic S, Pancevacki S, Neskovic A, Konstantinides S. Predictive value of heart failure with reduced versus preserved ejection fraction for outcome in pulmonary embolism. ESC Heart Fail. 2020 Dec;7(6):4061-4070

Kyselova A, Siragusa M, Anthes J, Solari FA, Loroch S, Zahedi RP, Walter U, Fleming I, Randriamboavonjy V. Cyclin Y is expressed in Platelets and Modulates Integrin Outside-in Signaling. Int J Mol Sci. 2020 Nov 3;21(21):8239

Ballesteros I, Rubio-Ponce A, Genua M, Lusito E, Kwok I, Fernández-Calvo G, Khoyratty TE, van Grinsven E, González-Hernández S, Nicolás-Ávila JÁ, Vicanolo T, Maccataio A, Benguría A, Li JL, Adrover JM, Aroca-Crevillen A, Quintana JA, Martín-Salamanca S, Mayo F, Ascher S, Barbiera G, Soehnlein O, Gunzer M, Ginhoux F, Sánchez-Cabo F, Nistal-Villán E, Schulz C, Dopazo A, Reinhardt C, Udalova IA, Ng LG, Ostuni R, Hidalgo A. Co-option of Neutrophil Fates by Tissue Environments. Cell. 2020 Nov 25;183(5):1282-1297.e18

Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 Nov 1;147(9):2564-2577

Comer S, Nagy Z, Bolado A, von Kriegsheim A, Gambaryan S, Walter U, Pagel O, Zahedi RP, Jurk K, Smolenski A. The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets. J Thromb Haemost. 2020 Nov;18(11):3002-3012

Saffarzadeh M, Grunz K, Nguyen TS, Lee YK, Kitano M, Danckwardt S, Rodrigues CDS, Weiler H, Reyda S, Ruf W. Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice. Blood Adv. 2020 Nov 24;4(22):5810-5824

Kriechbaum SD, Scherwitz L, Wiedenroth CB, Rudolph F, Wolter JS, Haas M, Fischer-Rasokat U, Rolf A, Hamm CW, Mayer E, Guth S, Keller T, Konstantinides SV, Lankeit M, Liebetrau C. Mid-regional pro-atrial natriuretic peptide and copeptin as indicators of disease severity and therapy response in CTEPH. ERJ Open Res. 2020 Nov 2;6(4):00356-2020

Tanabe S, Fujimura Y, Lämmle B, Kimura T, Isonishi A, Sakai K, Matsumoto M. Stealth thrombosis of brain and kidney in a girl with Upshaw-Schulman syndrome not receiving prophylactic plasma infusions. Int J Hematol. 2020 Nov;112(5):603-604

Ma J, Klemm J, Gerardo-Ramírez M, Frappart L, Castven D, Becker D, Zoch A, Parent R, Bartosch B, Minnich K, Giovannini M, Danckwardt S, Hartmann N, Morrison H, Herrlich P, Marquardt JU, Hartmann M. Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin. Int J Cancer. 2020 Nov 1;147(9):2564-2577

Makhoul S, Kumm E, Zhang P, Walter U, Jurk K. The Serine/Threonine Protein Phosphatase 2A (PP2A) Regulates Syk Activity in Human Platelets. Int J Mol Sci. 2020 Nov 25;21(23):8939

Pielsticker C, Brodde MF, Raum L, Jurk K, Kehrel BE. Plasmin-Induced Activation of Human Platelets Is Modulated by Thrombospondin-1, Bona Fide Misfolded Proteins and Thiol Isomerases. Int J Mol Sci. 2020 Nov 23;21(22):8851

Schrage B, Rübsamen N, Schulz A, Münzel T, Pfeiffer N, Wild PS, Beutel M, Schmidtmann I, Lott R, Blankenberg S, Zeller T, Lackner KJ, Karakas M. Iron deficiency is a common disorder in general population and independently predicts all-cause mortality: results from the Gutenberg Health Study. Clin Res Cardiol. 2020 Nov;109(11):1352-1357

Hobohm L, Anušić T, Konstantinides SV, Barco S; HoT-PE Investigators. Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT-PE) Trial. Eur Respir J. 2020 Oct 8;56(4):2000663

Panova-Noeva M, Wagner B, Nagler M, Koeck T, Ten Cate V, Prochaska JH, Heitmeier S, Meyer I, Gerdes C, Laux V, Konstantinides S, Spronk HM, Münzel T, Lackner KJ, Leineweber K, Ten Cate H, Wild PS. Comprehensive platelet phenotyping supports the role of platelets in the pathogenesis of acute venous thromboembolism - results from clinical observation studies. EBioMedicine. 2020 Oct;60:102978

Hobohm L, Keller K, Valerio L, Ni Ainle F, Klok FA, Münzel T, Kucher N, Lankeit M, Konstantinides SV, Barco S. Fatality rates and use of systemic thrombolysis in pregnant women with pulmonary embolism. ESC Heart Fail. 2020 Oct;7(5):2365-2372

Hendriks SV, Lankeit M, den Exter PL, Zondag W, Brouwer R, Eijsvogel M, Grootenboers MJ, Faber LM, Heller-Baan R, Hofstee HMA, Iglesias Del Sol A, Mairuhu ATA, Melissant CF, Peltenburg HG, van de Ree MA, Serné EH, Konstantinides S, Klok FA, Huisman MV; Vesta Investigators. Uncertain Value of High-sensitive Troponin T for Selecting Patients With Acute Pulmonary Embolism for Outpatient Treatment by Hestia Criteria. Acad Emerg Med. 2020 Oct;27(10):1043-1046

Escher F, Pietsch H, Aleshcheva G, Bock T, Baumeier C, Elsaesser A, Wenzel P, Hamm C, Westenfeld R, Schultheiss M, Gross U, Morawietz L, Schultheiss HP. Detection of viral SARS-CoV-2 genomes and histopathological changes in endomyocardial biopsies. ESC Heart Fail. 2020 Oct;7(5):2440-2447

Emrich T, Hahn F, Fleischmann D, Halfmann MC, Düber C, Varga-Szemes A, Escher F, Pefani E, Münzel T, Schultheiss HP, Kreitner KF, Wenzel P. T1 and T2 mapping to detect chronic inflammation in cardiac magnetic resonance imaging in heart failure with reduced ejection fraction. ESC Heart Fail. 2020 Oct;7(5):2544-2552

Sluka SHM, Stämpfli SF, Akhmedov A, Klein-Rodewald T, Sanz-Moreno A, Horsch M, Grest P, Rothmeier AS, Rathkolb B, Schrewe A, Beckers J, Neff F, Wolf E, Camici GG, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lüscher TF, Ruf W, Tanner FC. Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality. Haematologica. 2020 Oct 1;105(10):2484-2495

Keller K, Göbel S, Ten Cate V, Panova-Noeva M, Eggebrecht L, Nagler M, Coldewey M, Foebel M, Bickel C, Lauterbach M, Espinola-Klein C, Lackner KJ, Cate HT, Münzel T, Wild PS, H Prochaska J. Telemedicine-Based Specialized Care Improves the Outcome of Anticoagulated Individuals with Venous Thromboembolism-Results from the thrombEVAL Study. J Clin Med. 2020 Oct 13;9(10):3281

Sluka SHM, Stämpfli SF, Akhmedov A, Klein-Rodewald T, Sanz-Moreno A, Horsch M, Grest P, Rothmeier AS, Rathkolb B, Schrewe A, Beckers J, Neff F, Wolf E, Camici GG, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Lüscher TF, Ruf W, Tanner FC. Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality. Haematologica. 2020 Oct 1;105(10):2484-2495

Corsi G, Nava S, Barco S. Un nuovo strumento per misurare lo stato funzionale globale a lungo termine dei pazienti con malattia da coronavirus 2019: la scala PCFS (Post-COVID-19 Functional Status) [A novel tool to monitor the individual functional status after COVID-19: the Post-COVID-19 Functional Status (PCFS) scale]. G Ital Cardiol (Rome). 2020 Oct;21(10):757

van Paridon PCS, Panova-Noeva M, van Oerle R, Schultz A, Hermanns IM, Prochaska JH, Arnold N, Binder H, Schmidtmann I, Beutel ME, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS, Spronk HMH. Thrombin generation in cardiovascular disease and mortality - results from the Gutenberg Health Study. Haematologica. 2020 Sep 1;105(9):2327-2334

Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity. Front Immunol. 2020 Sep 11;11:2189

Wild J, Hobohm L, Münzel T, Wenzel P, Steinbrink K, Karbach S, Keller K. Psoriasis and Its Impact on In-Hospital Outcome in Patients Hospitalized with Acute Kidney Injury.https://pubmed.ncbi.nlm.nih.gov/32957680/ J Clin Med. 2020 Sep 17;9(9):3004

Valerio L, Zuin M, Mahmoudpour SH, Zuliani G, Zonzin P, Barco S, Roncon L. Aggiornamento sui dati relativi alla mortalità da embolia polmonare in Italia (2003-2015) [An update on pulmonary embolism-related mortality in Italy (2003-2015)]. G Ital Cardiol (Rome). 2020 Aug;21(8):639-646

Bell K, Beutgen VM, Nickels S, Lorenz K, Scheller Y, Elbaz H, Peto T, Ponto KA, Schulz A, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N, Grus FH, Schuster AK. Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. J Ophthalmol. 2020 Jul 29;2020:8386160

Kakkar AK, Bauersachs R, Falanga A, Wong J, Kayani G, Kahney A, Hughes R, Levine M. Fundamental Research in Oncology and Thrombosis 2 (FRONTLINE 2): A Follow-Up Survey. Oncologist. 2020 Jul;25(7):e1091-e1097. doi: 10.1634/theoncologist.2019-0676

Bonaca MP, Bauersachs RM, Anand SS, Debus ES, Nehler MR, Patel MR, Fanelli F, Capell WH, Diao L, Jaeger N, Hess CN, Pap AF, Kittelson JM, Gudz I, Mátyás L, Krievins DK, Diaz R, Brodmann M, Muehlhofer E, Haskell LP, Berkowitz SD, Hiatt WR. Rivaroxaban in Peripheral Artery Disease after Revascularization. N Engl J Med. 2020 May 21;382(21):1994-2004

Agnelli G, Becattini C, Meyer G, Muñoz A, Huisman MV, Connors JM, Cohen A, Bauersachs R, Brenner B, Torbicki A, Sueiro MR, Lambert C, Gussoni G, Campanini M, Fontanella A, Vescovo G, Verso M; Caravaggio Investigators. Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer. N Engl J Med. 2020 Apr 23;382(17):1599-1607

Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. Elife. 2020 Apr 21;9:e52511

Schuster AK, Nickels S, Pfeiffer N, Schmidtmann I, Wild PS, Münzel T, Beutel ME, Lackner KJ, Vossmerbaeumer U. 2020. Frequency of cataract surgery and its impact on visual function-results from the German Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 258:2223-2231.

Elbaz H, Schuster AK, Nickels S, Nagler M, Ponto KI, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Peto T. 2020. Epidemiologic Analysis of Asteroid Hyalosis and Associations: The Gutenberg Health Study. Ophthalmology doi:10.1016/j.ophtha.2020.07.008.

Klein EM, Brähler E, Petrowski K, Tibubos AN, Ernst M, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. 2020. The association between recalled parental rearing behavior and depressiveness: a comparison between 1st immigrants and non-immigrants in the population-based Gutenberg Health Study. BMC Psychiatry 20:367.

Reiner IC, Tibubos AN, Werner AM, Ernst M, Brähler E, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, Arnold N, Mahmoudpour SH, Lackner KJ, Pfeiffer N, Beutel ME. 2020. The association of chronic anxiousness with cardiovascular disease and mortality in the community: results from the Gutenberg Health Study. Sci Rep 10:12436.

Bell K, Beutgen VM, Nickels S, Lorenz K, Scheller Y, Elbaz H, Peto T, Ponto KA, Schulz A, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N, Grus FH, Schuster AK. 2020. Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients. J Ophthalmol 2020:8386160.

Ernst M, Reiner I, Fiess A, Tibubos AN, Schulz A, Burghardt J, Klein EM, Brähler E, Wild PS, Münzel T, König J, Lackner KJ, Pfeiffer N, Michal M, Wiltink J, Beutel ME. 2020. Sex-dependent associations of low birth weight and suicidal ideation in adulthood: a community-based cohort study. Sci Rep 10:12969.

Klein EM, Brähler E, Petrowski K, Tibubos AN, Burghardt J, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, König J, Lackner K, Pfeiffer N, Beutel ME. 2020. Recalled parental rearing behavior in adult women and men with depressive and anxiety symptoms: Findings from a community study. Z Psychosom Med Psychother 66:243-258.

Wagner FM, Hoffmann EM, Nickels S, Fiess A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. 2020. Peripapillary Retinal Nerve Fiber Layer Profile in Relation to Refractive Error and Axial Length: Results From the Gutenberg Health Study. Transl Vis Sci Technol 9:35.

Grill A, Kiouptsi K, Karwot C, Jurk K, Reinhardt C. 2020. Evaluation of blood collection methods and anticoagulants for platelet function analyses on C57BL/6J laboratory mice. Platelets 31:981-988.

Hobohm L, Anusic T, Konstantinides SV, Barco S, HoT-PE Investigators. 2020. Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT-PE) Trial. Eur Respir J 56.

Hauptmann J, Johann L, Marini F, Kitic M, Colombo E, Mufazalov IA, Krueger M, Karram K, Moos S, Wanke F, Kurschus FC, Klein M, Cardoso S, Strauss J, Bolisetty S, Luhder F, Schwaninger M, Binder H, Bechman I, Bopp T, Agarwal A, Soares MP, Regen T, Waisman A. 2020. Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood-brain barrier. Acta Neuropathol 140:549-567.

Pruszczyk P, Kurnicka K, Ciurzynski M, Hobohm L, Thielmann A, Sobkowicz B, Sawicka E, Kostrubiec M, Ptaszynska-Kopczynska K, Dzikowska-Diduch O, Lichodziejewska B, Lankeit M. 2020. Defining right ventricular dysfunction by echocardiography in normotensive patients with pulmonary embolism. Pol Arch Intern Med 130:741-747.

Krueger I, Gremer L, Mangels L, Klier M, Jurk K, Willbold D, Bock HH, Elvers M. 2020. Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases. Arterioscler Thromb Vasc Biol 40:2391-2403.

Valentin ML, Barco S, Studer G, Clemens R, Kreuzpointner R, Sebastian T, Thalhammer C, Kucher N. 2020. Prevalence of carotid plaque stenosis after head and neck radiotherapy – an observational study of 156 survivors. Vasa doi:10.1024/0301-1526/a000896:1-7.

Kiouptsi K, Jäckel S, Wilms E, Pontarollo G, Winterstein J, Karwot C, Gross K, Jurk K, Reinhardt C. 2020. The Commensal Microbiota Enhances ADP-Triggered Integrin alphaIIbbeta3 Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen. Int J Mol Sci 21.

Valerio L, Zuin M, Mahmoudpour SH, Zuliani G, Zonzin P, Barco S, Roncon L. 2020. [An update on pulmonary embolism-related mortality in Italy (2003-2015)]. G Ital Cardiol (Rome) 21:639-646.

Karbach S, Hobohm L, Wild J, Münzel T, Gori T, Wegner J, Steinbrink K, Wenzel P, Keller K. 2020. Impact of Psoriasis on Mortality Rate and Outcome in Myocardial Infarction. J Am Heart Assoc 9:e016956.

Swieringa F, Solari FA, Pagel O, Beck F, Huang J, Feijge MAH, Jurk K, Korver-Keularts I, Mattheij NJA, Faber J, Pohlenz J, Russo A, Stumpel C, Schrander DE, Zieger B, van der Meijden PEJ, Zahedi RP, Sickmann A, Heemskerk JWM. 2020. Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS. Sci Rep 10:11389.

Lehwald N, Duhme C, Pinchuk I, Kirchner J, Wieferich K, Schmelzle M, Jurk K, Windmoller BA, Hübner W, Homey B, Bode J, Kubitz R, Benhidjeb T, Krüger M, Robson SC, Knoefel WT, Kehrel BE, Schulte Am Esch J. 2020. Platelets Boost Recruitment of CD133(+) Bone Marrow Stem Cells to Endothelium and the Rodent Liver-The Role of P-Selectin/PSGL-1 Interactions. Int J Mol Sci 21.

Efentakis P, Doerschmann H, Witzler C, Siemer S, Nikolaou PE, Kastritis E, Stauber R, Dimopoulos MA, Wenzel P, Andreadou I, Terpos E. 2020. Investigating the Vascular Toxicity Outcomes of the Irreversible Proteasome Inhibitor Carfilzomib. Int J Mol Sci 21.

Gamrekelashvili J, Kapanadze T, Sablotny S, Ratiu C, Dastagir K, Lochner M, Karbach S, Wenzel P, Sitnow A, Fleig S, Sparwasser T, Kalinke U, Holzmann B, Haller H, Limbourg FP. 2020. Notch and TLR signaling coordinate monocyte cell fate and inflammation. Elife 9.

Escher F, Pietsch H, Aleshcheva G, Wenzel P, Fruhwald F, Stumpf C, Westermann D, Bauersachs J, Enseleit F, Ruschitzka F, Nägele H, Laugwitz KL, Haake H, Frey N, Brachmann J, Huber K, Braun-Dullaeus RC, Bergmann MW, Strotmann J, Grönefeld G, Krülls-Münch J, Westenfeld R, Skurk C, Landmesser U, Pieske B, Gross UM, Morawietz L, Schultheiss HP. 2020. Evaluation of Myocardial Gene Expression Profiling for Superior Diagnosis of Idiopathic Giant-Cell Myocarditis and Clinical Feasibility in a Large Cohort of Patients with Acute Cardiac Decompensation. J Clin Med 9.

Lagrange J, Finger S, Kossmann S, Garlapati V, Ruf W, Wenzel P. 2020. Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice. Int J Mol Sci 21.

Madhusudhan T, Ghosh S, Wang H, Dong W, Gupta D, Elwakiel A, Stoyanov S, Al-Dabet MM, Krishnan S, Biemann R, Nazir S, Zimmermann S, Mathew A, Gadi I, Rana R, Zeng-Brouwers J, Moeller MJ, Schaefer L, Esmon CT, Kohli S, Reiser J, Rezaie AR, Ruf W, Isermann B. 2020. Podocyte Integrin-beta 3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy. J Am Soc Nephrol 31:1762-1780.

Lagrange J, Wagner B, Nagler M, Ten Cate V, Pallares Robles A, Koeck T, Rapp S, Prochaska JH, Spronk HM, Wenzel P, Ruf W, Ten Cate H, Wild PS, Panova-Noeva M. 2020. Characterization of Thrombin Generation Curve Shape in Presence of Platelets from Acute Venous Thromboembolism Patients. J Clin Med 9.

Wiedenroth Md CB, Rieth Md AJ, Kriechbaum Md S, Ghofrani Md HA, Breithecker Md A, Haas Md M, Roller Md F, Richter Md MJ, Lankeit M, Mielzarek L, Rolf Md A, Hamm Md CW, Mayer Md E, Guth Md S, Liebetrau Md C. 2020. Exercise right heart catheterization before and after balloon pulmonary angioplasty in inoperable patients with chronic thromboembolic pulmonary hypertension. Pulm Circ 10:2045894020917884.

Schnorbus B, Daiber A, Jurk K, Warnke S, Koenig J, Lackner KJ, Münzel T, Gori T. 2020. Effects of clopidogrel vs. prasugrel vs. ticagrelor on endothelial function, inflammatory parameters, and platelet function in patients with acute coronary syndrome undergoing coronary artery stenting: a randomized, blinded, parallel study. Eur Heart J 41:3144-3152. 

Kuntic M, Oelze M, Steven S, Kröller-Schön S, Stamm P, Kalinovic S, Frenis K, Vujacic-Mirski K, Bayo Jimenez MT, Kvandova M, Filippou K, Al Zuabi A, Bruckl V, Hahad O, Daub S, Varveri F, Gori T, Huesmann R, Hoffmann T, Schmidt FP, Keaney JF, Daiber A, Münzel T. 2020. Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2). Eur Heart J 41:2472-2483.

Hopf S, Korb C, Nickels S, Schulz A, Münzel T, Wild PS, Michal M, Schmidtmann I, Lackner KJ, Pfeiffer N, Schuster AK. 2020. Prevalence of myopic maculopathy in the German population: results from the Gutenberg health study. Br J Ophthalmol 104:1254-1259.

Roose E, Schelpe AS, Tellier E, Sinkovits G, Joly BS, Dekimpe C, Kaplanski G, Le Besnerais M, Mancini I, Falter T, Von Auer C, Feys HB, Reti M, Rossmann H, Vandenbulcke A, Pareyn I, Voorberg J, Greinacher A, Benhamou Y, Deckmyn H, Fijnheer R, Prohaszka Z, Peyvandi F, Lämmle B, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K. 2020. Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura. Blood 136:353-361.

Hobohm L, Becattini C, Konstantinides SV, Casazza F, Lankeit M. 2020. Validation of a fast prognostic score for risk stratification of normotensive patients with acute pulmonary embolism. Clin Res Cardiol 109:1008-1017.

Steven S, Frenis K, Kalinovic S, Kvandova M, Oelze M, Helmstädter J, Hahad O, Filippou K, Kus K, Trevisan C, Schlüter KD, Boengler K, Chlopicki S, Frauenknecht K, Schulz R, Sorensen M, Daiber A, Kröller-Schön S, Münzel T. 2020. Exacerbation of adverse cardiovascular effects of aircraft noise in an animal model of arterial hypertension. Redox Biol 34:101515. 

Fiess A, Elflein HM, Urschitz MS, Pesudovs K, Münzel T, Wild PS, Michal M, Lackner KJ, Pfeiffer N, Nickels S, Schuster AK. 2020. Prevalence of Strabismus and Its Impact on Vision-Related Quality of Life: Results from the German Population-Based Gutenberg Health Study. Ophthalmology 127:1113-1122.

Döhrmann M, Makhoul S, Gross K, Krause M, Pillitteri D, von Auer C, Walter U, Lutz J, Volf I, Kehrel BE, Jurk K. 2020. CD36-fibrin interaction propagates FXI-dependent thrombin generation of human platelets. FASEB J doi:10.1096/fj.201903189R.

Keller K, Hobohm L, Münzel T, Ostad MA. 2020. Impact of concomitant deep or superficial venous thrombosis of the legs on survival of patients with pulmonary embolism. Int J Cardiol 315:92-98.

Keller K, Hobohm L, Geyer M, Kreidel F, Ostad MA, Lavie CJ, Lankeit M, Konstantinides S, Münzel T, von Bardeleben RS. 2020. Impact of obesity on adverse in-hospital outcomes in patients undergoing percutaneous mitral valve edge-to-edge repair using MitraClip(R) procedure - Results from the German nationwide inpatient sample. Nutr Metab Cardiovasc Dis 30:1365-1374.

Wenzel P, Kopp S, Göbel S, Jansen T, Geyer M, Hahn F, Kreitner KF, Escher F, Schultheiss HP, Münzel T. 2020. Evidence of SARS-CoV-2 mRNA in endomyocardial biopsies of patients with clinically suspected myocarditis tested negative for COVID-19 in nasopharyngeal swab. Cardiovasc Res 116:1661-1663.

Sebastian T, Barco S, Engelberger RP, Spirk D, Schindewolf M, Baumann F, Baumgartner I, Kucher N. 2020. Duplex Ultrasound Investigation for the Detection of Obstructed Iliocaval Venous Stents. Eur J Vasc Endovasc Surg 60:443-450.

Ascher S, Wilms E, Pontarollo G, Formes H, Bayer F, Müller M, Malinarich F, Grill A, Bosmann M, Saffarzadeh M, Brandao I, Gross K, Kiouptsi K, Kittner JM, Lackner KJ, Jurk K, Reinhardt C. 2020. Gut Microbiota Restricts NETosis in Acute Mesenteric Ischemia-Reperfusion Injury. Arterioscler Thromb Vasc Biol 40:2279-2292.

Keller K, Hobohm L, Münzel T, Konstantinides SV, Lankeit M. 2020. Sex-specific and age-related seasonal variations regarding incidence and in-hospital mortality of pulmonary embolism in Germany. ERJ Open Res 6.

Keller K, Hobohm L, Ostad MA, Göbel S, Lankeit M, Konstantinides S, Münzel T, Wenzel P. 2020. Temporal trends and predictors of inhospital death in patients hospitalised for heart failure in Germany. Eur J Prev Cardiol doi:10.1177/2047487320936020:2047487320936020.

Roewe J, Stavrides G, Strueve M, Sharma A, Marini F, Mann A, Smith SA, Kaya Z, Strobl B, Mueller M, Reinhardt C, Morrissey JH, Bosmann M. 2020. Bacterial polyphosphates interfere with the innate host defense to infection. Nat Commun 11:4035.

Keller P, von Kanel R, Hincapie CA, da Costa BR, Juni P, Erlanger TE, Andina N, Niederhauser C, Lämmle B, Fontana S. 2020. The effects of intravenous iron supplementation on fatigue and general health in non-anemic blood donors with iron deficiency: a randomized placebo-controlled superiority trial. Sci Rep 10:14219.

Soneson C, Marini F, Geier F, Love MI, Stadler MB. 2020. ExploreModelMatrix: Interactive exploration for improved understanding of design matrices and linear models in R. F1000Res 9:512.

Mohebiany AN, Ramphal NS, Karram K, Di Liberto G, Novkovic T, Klein M, Marini F, Kreutzfeldt M, Hartner F, Lacher SM, Bopp T, Mittmann T, Merkler D, Waisman A. 2020. Microglial A20 Protects the Brain from CD8 T-Cell-Mediated Immunopathology. Cell Rep 30:1585-1597 e6. 

Barco S, Sollfrank S, Trinchero A, Adenaeuer A, Abolghasemi H, Conti L, Hauser F, Kremer Hovinga JA, Lackner KJ, Loewecke F, Miloni E, Vazifeh Shiran N, Tomao L, Wuillemin WA, Zieger B, Lämmle B, Rossmann H. Severe plasma prekallikrein deficiency: Clinical characteristics, novel KLKB1 mutations, and estimated prevalence. J Thromb Haemost 2020;18(7):1598-1617.

Kiouptsi K, Pontarollo G, Todorov H, Braun J, Jäckel S, Koeck T, Bayer F, Karwot C, Karpi A, Gerber S, Jansen Y, Wild P, Ruf W, Daiber A, Van Der Vorst E, Weber C, Döring Y, Reinhardt C. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. Gut Microbes 2020;11(6):1809-1823.

Ten Cate V, Eggebrecht L, Schulz A, Panova-Noeva M, Lenz M, Koeck T, Rapp S, Arnold N, Lackner KJ, Konstantinides S, Espinola-Klein C, Münzel T, Prochaska JH, Wild PS. Isolated Pulmonary Embolism Is Associated With a High Risk of Arterial Thrombotic Disease: Results From the VTEval Study. Chest 2020;158(1):341-349.

Schlax J, Wiltink J, Beutel ME, Münzel T, Pfeiffer N, Wild P, Blettner M, Ghaemi Kerahrodi J, Michal M. Symptoms of depersonalization/derealization are independent risk factors for the development or persistence of psychological distress in the general population: Results from the Gutenberg health study. J Affect Disord 2020;273:41-47.

Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, Kucher N, Studt JD, Sacco C, Alexia B, Sandri MT, Barco S, Humanitas C-TF. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020;191:9-14.

Lindhoff-Last E, Herrmann E, Lindau S, Konstantinides S, Grottke O, Nowak-Goettl U, Lucks J, Zydek B, Heymann CV, Birschmann I, Sumnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A. Severe Hemorrhage Associated With Oral Anticoagulants. Dtsch Arztebl Int 2020;117(18):312-319.

Beutel ME, Brähler E, Ernst M, Klein E, Reiner I, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, Hahad O, Konig J, Lackner KJ, Pfeiffer N, Tibubos AN. Noise annoyance predicts symptoms of depression, anxiety and sleep disturbance 5 years later. Findings from the Gutenberg Health Study. Eur J Public Health 2020;30(3):516-521.

Keller K, Hobohm L, Barco S, Schmidtmann I, Münzel T, Engelhardt M, Goldhofer M, Konstantinides SV, Drees P. Venous thromboembolism in patients hospitalized for hip joint replacement surgery. Thromb Res 2020;190:1-7. 

Romero Starke K, Hegewald J, Schulz A, Garthus-Niegel S, Nubling M, Wild PS, Arnold N, Latza U, Jankowiak S, Liebers F, Rossnagel K, Riechmann-Wolf M, Letzel S, Beutel M, Pfeiffer N, Lackner K, Münzel T, Seidler A. Cardiovascular health outcomes of mobbing at work: results of the population-based, five-year follow-up of the Gutenberg health study. J Occup Med Toxicol 2020;15:15.

Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Cell 2020;181(5):1080-1096 e1019

Kroone C, Vos M, Rademakers T, Kuijpers M, Hoogenboezem M, van Buul J, Heemskerk JWM, Ruf W, van Hylckama Vlieg A, Versteeg HH, Goumans MJ, de Vries CJM, Kurakula K, Consortium I. LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis. Haematologica 2020;105(6):1677-1685.

Boon G, Barco S, Bertoletti L, Ghanima W, Huisman MV, Kahn SR, Noble S, Prandoni P, Rosovsky RP, Sista AK, Siegerink B, Klok FA. Measuring functional limitations after venous thromboembolism: Optimization of the Post-VTE Functional Status (PVFS) Scale. Thromb Res 2020;190:45-51.

Nayor M, Short MI, Rasheed H, Lin H, Jonasson C, Yang Q, Hveem K, Felix JF, Morrison AC, Wild PS, Morley MP, Cappola TP, Benson MD, Group CH-HFW, Consortium CH-E, Ngo D, Sinha S, Keyes MJ, Shen D, Wang TJ, Larson MG, Brumpton BM, Gerszten RE, Omland T, Vasan RS. Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits. Circ Heart Fail 2020;13(5):e006749.

Kaemmerer H, Gorenflo M, Huscher D, Pittrow D, Apitz C, […] Konstantinides S, […] Wilkens H, Wirtz H, Diller GP, Grunig E, Rosenkranz S. Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry. J Clin Med 2020;9(5).

Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. Elife 2020;9.

Nickels S, Blom HJ, Schulz A, Joachimsen L, Münzel T, Wild PS, Beutel ME, Blettner M, Lackner KJ, Pfeiffer N, Lagreze WA. No evidence for an association of plasma homocysteine levels and refractive error - Results from the population-based Gutenberg Health Study (GHS). PLoS One 2020;15(4):e0231011.

Ernst M, Brähler E, Klein EM, Jünger C, Wild PS, Faber J, Schneider A, Beutel ME. What's past is prologue: Recalled parenting styles are associated with childhood cancer survivors' mental health outcomes more than 25 years after diagnosis. Soc Sci Med 2020;252:112916.

Rezapour J, Schuster AK, Nickels S, Korb CA, Elbaz H, Peto T, Michal M, Münzel T, Wild PS, König J, Lackner K, Schulz A, Pfeiffer N, Beutel ME. Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort. Sci Rep 2020;10(1):4816.

Lauterbach M, Uhrich E, Eggebrecht L, Göbel S, Panova-Noeva M, Nagler M, Ten Cate V, Bickel C, Espinola-Klein C, Münzel T, Wild PS, Prochaska JH. Specialized Management of Oral Anticoagulation Therapy Improves Outcome in Patients with Chronic Renal Insufficiency. J Clin Med 2020;9(3).

White RJ, Jerjes-Sanchez C, Bohns Meyer GM, Pulido T, Sepulveda P, Wang KY, Grunig E, Hiremath S, Yu Z, Gangcheng Z, Yip WLJ, Zhang S, Khan A, Deng CQ, Grover R, Tapson VF, Freedom-Ev Investigators. Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial. Am J Respir Crit Care Med 2020;201(6):707-717.

Ernst M, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. The desire for children among adult survivors of childhood cancer: Psychometric evaluation of a cancer-specific questionnaire and relations with sociodemographic and psychological characteristics. Psychooncology 2020;29(3):485-492.

Schuster AK, Kluck AK, Korb CA, Stoffelns B, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N. Characteristics and pathologies of the vitreo-macular interface-results from the Gutenberg Health Study. Acta Ophthalmol 2020;98(3):e273-e281.

Keller K, Hobohm L, Wenzel P, Münzel T, Espinola-Klein C, Ostad MA. Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients. Heart Rhythm 2020;17(3):383-390. 

Barco S, Mahmoudpour SH, Valerio L, Klok FA, Münzel T, Middeldorp S, Ageno W, Cohen AT, Hunt BJ, Konstantinides SV. Trends in mortality related to pulmonary embolism in the European Region, 2000-15: analysis of vital registration data from the WHO Mortality Database. Lancet Respir Med 2020;8(3):277-287.

Todorov H, Kollar B, Bayer F, Brandao I, Mann A, Mohr J, Pontarollo G, Formes H, Stauber R, Kittner JM, Endres K, Watzer B, Nockher WA, Sommer F, Gerber S, Reinhardt C. alpha-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine. Nutrients 2020;12(3).

Amezquita RA, Lun ATL, Becht E, Carey VJ, Carpp LN, Geistlinger L, Marini F, Rue-Albrecht K, Risso D, Soneson C, Waldron L, Pages H, Smith ML, Huber W, Morgan M, Gottardo R, Hicks SC. Orchestrating single-cell analysis with Bioconductor. Nat Methods 2020;17(2):137-145.

Schuster AK, Leuschner A, Feretos C, Blumenstein P, Troebs SO, Schwuchow S, Schulz A, Nickels S, Mirshahi A, Blettner M, Beutel ME, Lackner KJ, Münzel T, Pfeiffer N, Wild PS. Choroidal thickness is associated with cardiovascular risk factors and cardiac health: the Gutenberg Health Study. Clin Res Cardiol 2020;109(2):172-182.

Hampel U, Schuster AK, Nickels S, Schulz A, Lackner KJ, Münzel T, Wild PS, Beutel M, Schmidtmann I, Pfeiffer N. Schirmer test results: are they associated with topical or systemic medication? Ocul Surf 2020;18(1):141-147.

Helmstädter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Kröller-Schön S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Münzel T, Daiber A, Steven S. Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension. Arterioscler Thromb Vasc Biol 2020;40(1):145-158.

Gresele P, Orsini S, Noris P, Falcinelli E, Alessi MC, Bury L, Borhany M, Santoro C, Glembotsky AC, Cid AR, Tosetto A, De Candia E, Fontana P, Guglielmini G, Pecci A, Bat-Val study investigators. Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC. J Thromb Haemost 2020;18(3):732-739. 

Hollerbach A, Müller-Calleja N, Canisius A, Orning C, Lackner KJ. Induction of tissue factor expression by anti-beta2-glycoprotein I is mediated by tumor necrosis factor alpha. J Thromb Thrombolysis 2020;49(2):228-234.

Mufazalov IA, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, Tang Y, Schüler R, Eich C, Wunderlich FT, Karbach SH, Bluestone JA, Korn T, Waisman A. Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R alpha-Chain Expression. J Immunol 2020;204(4):747-751.

Ernst M, Brähler E, Wild PS, Jünger C, Faber J, Schneider A, Beutel ME. Risk factors for suicidal ideation in a large, registry-based sample of adult long-term childhood cancer survivors. J Affect Disord 2020;265:351-356.

Burghardt J, Tibubos AN, Otten D, Brähler E, Binder H, Grabe H, Kruse J, Ladwig KH, Schomerus G, Wild PS, Beutel ME. A multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany. BMJ Open 2020;10(2):e034220.

Münzel T, Steven S, Hahad O, Daiber A. The sixth sense is involved in noise-induced stress responses and vascular inflammation: evidence for heightened amygdalar activity in response to transport noise in man. Eur Heart J 2020;41(6):783-785.

Kumm EJ, Pagel O, Gambaryan S, Walter U, Zahedi RP, Smolenski A, Jurk K. The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets. Cells 2020;9(2).

Efentakis P, Varela A, Chavdoula E, Sigala F, Sanoudou D, Tenta R, Gioti K, Kostomitsopoulos N, Papapetropoulos A, Tasouli A, Farmakis D, Davos CH, Klinakis A, Suter T, Cokkinos DV, Iliodromitis EK, Wenzel P, Andreadou I. Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy. Cardiovasc Res 2020;116(3):576-591.

Chen W, Werner F, Illerhaus A, Knopp T, Völker K, Potapenko T, Hofmann U, Frantz S, Baba HA, Rösch M, Zernecke A, Karbach S, Wenzel P, Kuhn M. Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide). Arterioscler Thromb Vasc Biol 2020;40(3):682-696.

Meyer M, Wild J, Hirschmann M, Dimitriadis Z, Münzel T, Gori T, Wenzel P. Predictors for Target Vessel Failure after Recanalization of Chronic Total Occlusions in Patients Undergoing Surveillance Coronary Angiography. J Clin Med 2020;9(1).

Witkowski M, Witkowski M, Saffarzadeh M, Friebel J, Tabaraie T, Ta Bao L, Chakraborty A, Dorner A, Stratmann B, Tschoepe D, Winter SJ, Krueger A, Ruf W, Landmesser U, Rauch U. Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes. Cardiovasc Diabetol 2020;19(1):20.

Krieg VJ, Hobohm L, Liebetrau C, Guth S, Kölmel S, Troidl C, Mayer E, Konstantinides SV, Wiedenroth CB, Lankeit M. Risk factors for chronic thromboembolic pulmonary hypertension - Importance of thyroid disease and function. Thromb Res 2020;185:20-26.

Keller K, Hobohm L, Ebner M, Kresoja KP, Münzel T, Konstantinides SV, Lankeit M. Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany. Eur Heart J 2020;41(4):522-529.

Ebner M, Kresoja KP, Keller K, Hobohm L, Rogge NIJ, Hasenfuss G, Pieske B, Konstantinides SV, Lankeit M. Temporal trends in management and outcome of pulmonary embolism: a single-centre experience. Clin Res Cardiol 2020;109(1):67-77.

Bochenek ML, Leidinger C, Rosinus NS, Gogiraju R, Guth S, Hobohm L, Jurk K, Mayer E, Münzel T, Lankeit M, Bosmann M, Konstantinides S, Schäfer K. Activated Endothelial TGFbeta1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension. Circ Res 2020;126(2):162-181.

Ebner M, Rogge NIJ, Parwani AS, Sentler C, Lerchbaumer MH, Pieske B, Konstantinides SV, Hasenfuss G, Wachter R, Lankeit M. Atrial fibrillation is frequent but does not affect risk stratification in pulmonary embolism. J Intern Med 2020;287(1):100-113.

Barco S, Schmidtmann I, Ageno W, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jimenez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Manolis A, Meyer A, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Westerweel PE, Wild PS, Konstantinides SV, Lankeit M, HoT-PE Investigators. Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multicentre single-arm clinical trial. Eur Heart J 2020;41(4):509-518.

Barco S, Klok FA, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Simonneau G, Delcroix M, Lang IM. Sex-specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry. J Thromb Haemost 2020;18(1):151-161.

Visser M, van Oerle R, Ten Cate H, Laux V, Mackman N, Heitmeier S, Spronk HMH. Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX. Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):103-111

Weitz JI, Bauersachs R, Becker B, Berkowitz SD, Freitas MCS, Lassen MR, Metzig C, Raskob GE. Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: The FOXTROT Randomized Clinical Trial. JAMA. 2020 Jan 14;323(2):130-139

Reviews 2020

Ruf W, Graf C. 2020. Coagulation signaling and cancer immunotherapy. Thromb Res 191 Suppl 1:S106-S111.

Valerio L, Corsi G, Sebastian T, Barco S. Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry. Thromb Res. 2020 Dec;196:494-499

Schulman S, Hu Y, Konstantinides S. Venous Thromboembolism in COVID-19. Thromb Haemost. 2020 Dec;120(12):1642-1653

Hart C, Bauersachs R, Scholz U, Zotz R, Bergmann F, Rott H, Linnemann B. Prevention of Venous Thromboembolism during Pregnancy and the Puerperium with a Special Focus on Women with Hereditary Thrombophilia or Prior VTE-Position Paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH). Hamostaseologie. 2020 Dec;40(5):572-590

Ebner M, Lankeit M. 2020. [Antithrombotic Treatment of Pulmonary Embolism]. Dtsch Med Wochenschr 145:970-977.

Lämmle B. Clinical Problem Solving and Using New Paths in the Laboratory: Learning from Case Studies. Hamostaseologie. 2020 Nov;40(4):414-419

Geyer M, Wild J, Münzel T, Gori T, Wenzel P. State of the Art-High-Sensitivity Troponins in Acute Coronary Syndromes. Cardiol Clin. 2020 Nov;38(4):471-479

Bikdeli B, Madhavan MV, Gupta A, Jimenez D, Burton JR, Der Nigoghossian C, Chuich T, Nouri SN, Dreyfus I, Driggin E, [...], Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global, Covid-Thrombosis Collaborative Group. 2020. Pharmacological Agents Targeting Thromboinflammation in COVID-19: Review and Implications for Future Research. Thromb Haemost 120:1004-1024.

Konstantinides S, Meyer G. 2020. Management of acute pulmonary embolism 2019: what is new in the updated European guidelines? Intern Emerg Med 15:957-966. 

Wild J, Wegner J, Karbach S. Von der Haut zum Gefäßsystem – Psoriasis und das kardiovaskuläre Risiko. Der Kardiologe 14, 205–211

Hobohm L, Keller K, Münzel T, Gori T, Konstantinides SV. EkoSonic® endovascular system and other catheter-directed treatment reperfusion strategies for acute pulmonary embolism: overview of efficacy and safety outcomes. Expert Rev Med Devices. 2020 Aug;17(8):739-749

Escher R, Breakey N, Lämmle B. Severe COVID-19 infection associated with endothelial activation. Thromb Res 2020;190:62.

Göbel S, Hobohm L, Ostad MA, Lavie CJ, Gori T, Münzel T, Wenzel P, Keller K. Sex-specific differences drive temporal trends and outcomes of patients hospitalized for heart failure in Germany. Prog Cardiovasc Dis. 2020 Sep-Oct;63(5):591-598

Valerio L, Riva N. Head, Neck, and Abdominopelvic Septic Thrombophlebitis: Current Evidence and Challenges in Diagnosis and Treatment. Hamostaseologie. 2020 Aug;40(3):301-310

Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Giri J, Cushman M, Quere I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Caprini JA, Tafur AJ, Burton JR, Francese DP, Wang EY, Falanga A, McLintock C, Hunt BJ, Spyropoulos AC, Barnes GD, Eikelboom JW, Weinberg I, Schulman S, Carrier M, Piazza G, Beckman JA, Steg PG, Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global Covid-19 Thrombosis Collaborative Group EbtINE, the Iua SbtESCWGoPC, Right Ventricular F. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol 2020;75(23):2950-2973.

Ebner M, Lankeit M. [Update diagnosis and therapeutic management of pulmonary embolism]. Dtsch Med Wochenschr 2020;145(11):710-715.

Nourse J, Spada S, Danckwardt S. Emerging Roles of RNA 3'-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules 2020;10(6). 

Kiouptsi K, Reinhardt C. Physiological Roles of the von Willebrand Factor-Factor VIII Interaction. Subcell Biochem 2020;94:437-464.

Lutz J, Jurk K. Platelets in Advanced Chronic Kidney Disease: Two Sides of the Coin. Semin Thromb Hemost 2020;46(3):342-356.

Bauersachs R, Khorana AA, Lee AYY, Soff G. Cancer-associated venous thromboembolism: Treatment and prevention with rivaroxaban. Res Pract Thromb Haemost. 2020 Apr 4;4(4):532-549

Stakos D, Skendros P, Konstantinides S, Ritis K. Traps N' Clots: NET-Mediated Thrombosis and Related Diseases. Thromb Haemost 2020;120(3):373-383.

Barco S, Sebastian T. Death from, with, and without pulmonary embolism. Eur J Intern Med 2020;73:25-26.

Ward CM, Andrews RK, ISTH State of the Art Speakers. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia. Res Pract Thromb Haemost 2019;3(3):431-497.

Pontarollo G, Mann A, Brandao I, Malinarich F, Schöpf M, Reinhardt C. Protease-activated receptor signaling in intestinal permeability regulation. FEBS J 2020;287(4):645-658.

Pontarollo G, Kiouptsi K, Reinhardt C. A holobiont view on thrombosis: unravelling the microbiota's influence on arterial thrombus growth. Microb Cell 2020;7(1):28-31.

Bauersachs RM, Herold J. Oral Anticoagulation in the Elderly and Frail. Hamostaseologie. 2020 Feb;40(1):74-83

Meyer G, Konstantinides S. Should oral anticoagulation be discontinued after 3 months in the setting of a first high-risk pulmonary embolism secondary to a major transient/reversible risk factor? Eur Respir J 2020;55(1).

Pruszczyk P, Konstantinides S. Where to treat patients with acute pulmonary embolism? Kardiol Pol 2020;78(1):15-19.

Editorials und Fachbeiträge 2020

Konstantinides SV. Home treatment of pulmonary embolism: are all the questions answered now after the HOME-PE trial? Cardiovasc Res. 2020 Nov 1;116(13):e179-e181

Jara-Palomares L, Solier-López A, Russo M, Suñer M, González-Roncero F, Peters-Sengers H, Middeldorp S, Bemelman FJ, Barco S. Thromboprophylaxis after renal transplantation and patient risk stratification: The case of mTOR inhibitors. Thromb Res. 2020 Nov;195:100-102

Zuin M, Barco S, Zuliani G, Roncon L. Management of high-risk pulmonary embolism in an "unstable medical environment": Not only a matter of hemodynamic. Thromb Res. 2020 Nov;195:193-194

Valerio L, Barco S. 2020. Risk stratification of normotensive pulmonary embolism: One more ride on the merry-go-round. Eur Heart J Acute Cardiovasc Care 9:256-258.

Barco S. 2020. The Millennial Generation of Thrombosis and Hemostasis. Hamostaseologie 40:259-261

Klok FA, Barco S. Anticoagulation in splanchnic and cerebral vein thrombosis: Still groping in the dark. Res Pract Thromb Haemost. 2020 Sep 14;4(7):1080-1082

Bosmann M. 2020. Complement Activation during Critical Illness: Current Findings and an Outlook in the Era of COVID-19. Am J Respir Crit Care Med 202:163-165.

Klok FA, Boon G, Barco S, Endres M, Geelhoed JJM, Knauss S, Rezek SA, Spruit MA, Vehreschild J, Siegerink B. 2020. The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19. Eur Respir J 56.

Schulman S, Konstantinides S, Hu Y, Tang LV. 2020. Venous Thromboembolic Diseases: Diagnosis, Management and Thrombophilia Testing: Observations on NICE Guideline [NG158]. Thromb Haemost 120:1143-1146.

Barco S, Konstantinides SV, Investigators C-T. 2020. Thrombosis and thromboembolism related to COVID-19: A clarion call for obtaining solid estimates from large-scale multicenter data. Res Pract Thromb Haemost 4:741-743. 

Konstantinides SV. 2020. Thrombosis and Thromboembolism Related to COVID-19: Increase the Level of Awareness, Lower the Threshold of Suspicion, and Keep Following the Guidelines. JACC Case Rep 2:1388-1390.

Barco S, Münger M, Sebastian T, Kucher N. Reperfusion treatment for high-risk pulmonary embolism associated with COVID-19. Vasa 2020;49(4):257-258.

Konstantinides S, Lankeit M, Erbel C, Tiefenbacher C. Comments on the guidelines (2019) of the European Society of Cardiology on the management of acute pulmonary embolism With the collaboration of the European Respiratory Society (ERS). European Society of Cardiology zum Management der akuten Lungenembolie. Kardiologe (2020). doi.org/10.1007/s12181-020-00389-x  

Wild PS, Dimmeler S, Eschenhagen T. An epidemiological study exploring a possible impact of treatment with ACE inhibitors or angiotensin receptor blockers on ACE2 plasma concentrations. J Mol Cell Cardiol 2020;141:108-109.

Konstantinides SV. The optimal imaging test for diagnosis of acute pulmonary embolism: a second chance for lung scintigraphy? Eur Respir J 2020;55(6).

Escher R, Breakey N, Lämmle B. ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients. Thromb Res 2020;192:174-175.

Tziakas DN, Pavlaki M, Chalikias G, Konstantinides SV, Schäfer K. Letter by Tziakas et al Regarding Article, "Aortic Valve Stenosis: From Basic Mechanisms to Novel Therapeutic Targets". Arterioscler Thromb Vasc Biol 2020;40(6):e180-e181.

Konstantinides SV. Chronic thromboembolic disease following pulmonary embolism: more work ahead. Eur Respir J 2020;55(4).

Ruf W. TRIF turns the switch for DIC in sepsis. Blood 2020;135(14):1073-1074.

Barco S, Konstantinides SV. Predicting Venous Thromboembolism in Primary Care. Thromb Haemost 2020;120(4):531-533.

d'Alessandro E, Becker C, Bergmeier W, Bode C, Bourne JH, Brown H, Buller HR, Ten Cate-Hoek AJ, Ten Cate V, van Cauteren YJM, Cheung YFH, Cleuren A, Coenen D, Crijns H, de Simone I, Dolleman SC, Klein CE, Fernandez DI, Granneman L, van THA, Henke P, Henskens YMC, Huang J, Jennings LK, Jooss N, Karel M, van den Kerkhof D, Klok FA, Kremers B, Lämmle B, Leader A, Lundstrom A, Mackman N, Mannucci PM, Maqsood Z, van der Meijden PEJ, van Moorsel M, Moran LA, Morser J, van Mourik M, Navarro S, Neagoe RAI, Olie RH, van Paridon P, Posma J, Provenzale I, Reitsma PH, Scaf B, Schurgers L, Seelig J, Siegbahn A, Siegerink B, Soehnlein O, Soriano EM, Sowa MA, Spronk HMH, Storey RF, Tantiwong C, Veninga A, Wang X, Watson SP, Weitz J, Zeerleder SS, Ten Cate H, Scientific Reviewer C. Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2020;120(4):538-564.

Coppo P, Lämmle B. Animal models of thrombotic thrombocytopenic purpura: the tales from zebrafish. Haematologica 2020;105(4):861-863.

Konstantinides S. 2019 ESC guidelines on pulmonary embolism: Novelties and unanswered questions. Eur J Intern Med 2020;74:1-4.

Knopp T, Karbach S, Wenzel P. Myeloid Cells to the Rescue: Improving Thrombus Resolution. Thromb Haemost 2020;120(2):197-198.

Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ni Ainle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, ESC Scientific Document Group. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41(4):543-603.

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Editorials und Fachbeiträge 2013

  • Mirshahi A, Ponto KA, Hohn R, Wild PS, Pfeiffer N. Ophthalmological aspects of the Gutenberg Health Study (GHS): an interdisciplinary prospective population-based cohort study. Ophthalmologe 2013 Mar; 110(3):210-7 (P1B)
  • Lankeit M, Konstantinides S. Lungenembolie - Update 2013. Deutsche Medizinische Wochenschrift 138. Jahrgang, 31/32 2013 (P1C)
  • Konstantinides S, Lankeit M. Diagnostik im Dialog. News der Roche Diagnostics Deutschland GmbH 2013, Ausgabe 39, 2/2013 (P1C)
  • Schinzel H, Hendelmeier M. Therapie der frischen tiefen Beinvenenthrombose. Deutsche Medizinische Wochenschrift 2013, 138: 786-791
  • Konstantinides S, Lankeit M. Risikostratifizierung bei Lungenembolie: Stellwert kardialer Troponine. Diagnostik im Dialog 2013; Ausgabe 29, 2/2013 (JG1C)

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