Publikationen

2020  -  2019  -  2018  -  2017  -  2016  -  2015   -  2014  -  2013  -  2012  -  2011

Originalartikel 2020

• Barco S, Sollfrank S, Trinchero A, Adenaeuer A, Abolghasemi H, Conti L, Hauser F, Kremer Hovinga JA, Lackner KJ, Loewecke F, Miloni E, Vazifeh Shiran N, Tomao L, Wuillemin WA, Zieger B, Lämmle B, Rossmann H. Severe plasma prekallikrein deficiency: Clinical characteristics, novel KLKB1 mutations, and estimated prevalence. J Thromb Haemost 2020;18(7):1598-1617.

• Kiouptsi K, Pontarollo G, Todorov H, Braun J, Jäckel S, Koeck T, Bayer F, Karwot C, Karpi A, Gerber S, Jansen Y, Wild P, Ruf W, Daiber A, Van Der Vorst E, Weber C, Döring Y, Reinhardt C. Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice. Gut Microbes 2020;11(6):1809-1823.

• Ten Cate V, Eggebrecht L, Schulz A, Panova-Noeva M, Lenz M, Koeck T, Rapp S, Arnold N, Lackner KJ, Konstantinides S, Espinola-Klein C, Münzel T, Prochaska JH, Wild PS. Isolated Pulmonary Embolism Is Associated With a High Risk of Arterial Thrombotic Disease: Results From the VTEval Study. Chest 2020;158(1):341-349.

• Schlax J, Wiltink J, Beutel ME, Münzel T, Pfeiffer N, Wild P, Blettner M, Ghaemi Kerahrodi J, Michal M. Symptoms of depersonalization/derealization are independent risk factors for the development or persistence of psychological distress in the general population: Results from the Gutenberg health study. J Affect Disord 2020;273:41-47.

• Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, Kucher N, Studt JD, Sacco C, Alexia B, Sandri MT, Barco S, Humanitas C-TF. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020;191:9-14.

• Lindhoff-Last E, Herrmann E, Lindau S, Konstantinides S, Grottke O, Nowak-Goettl U, Lucks J, Zydek B, Heymann CV, Birschmann I, Sumnig A, Beyer-Westendorf J, Schellong S, Meybohm P, Greinacher A. Severe Hemorrhage Associated With Oral Anticoagulants. Dtsch Arztebl Int 2020;117(18):312-319.

• Beutel ME, Brähler E, Ernst M, Klein E, Reiner I, Wiltink J, Michal M, Wild PS, Schulz A, Münzel T, Hahad O, Konig J, Lackner KJ, Pfeiffer N, Tibubos AN. Noise annoyance predicts symptoms of depression, anxiety and sleep disturbance 5 years later. Findings from the Gutenberg Health Study. Eur J Public Health 2020;30(3):516-521.

• Keller K, Hobohm L, Barco S, Schmidtmann I, Münzel T, Engelhardt M, Goldhofer M, Konstantinides SV, Drees P. Venous thromboembolism in patients hospitalized for hip joint replacement surgery. Thromb Res 2020;190:1-7. 

• Romero Starke K, Hegewald J, Schulz A, Garthus-Niegel S, Nubling M, Wild PS, Arnold N, Latza U, Jankowiak S, Liebers F, Rossnagel K, Riechmann-Wolf M, Letzel S, Beutel M, Pfeiffer N, Lackner K, Münzel T, Seidler A. Cardiovascular health outcomes of mobbing at work: results of the population-based, five-year follow-up of the Gutenberg health study. J Occup Med Toxicol 2020;15:15.

• Schaupp L, Muth S, Rogell L, Kofoed-Branzk M, Melchior F, Lienenklaus S, Ganal-Vonarburg SC, Klein M, Guendel F, Hain T, Schütze K, Grundmann U, Schmitt V, Dorsch M, Spanier J, Larsen PK, Schwanz T, Jäckel S, Reinhardt C, Bopp T, Danckwardt S, Mahnke K, Heinz GA, Mashreghi MF, Durek P, Kalinke U, Kretz O, Huber TB, Weiss S, Wilhelm C, Macpherson AJ, Schild H, Diefenbach A, Probst HC. Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells. Cell 2020;181(5):1080-1096 e1019

• Kroone C, Vos M, Rademakers T, Kuijpers M, Hoogenboezem M, van Buul J, Heemskerk JWM, Ruf W, van Hylckama Vlieg A, Versteeg HH, Goumans MJ, de Vries CJM, Kurakula K, Consortium I. LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis. Haematologica 2020;105(6):1677-1685.

• Boon G, Barco S, Bertoletti L, Ghanima W, Huisman MV, Kahn SR, Noble S, Prandoni P, Rosovsky RP, Sista AK, Siegerink B, Klok FA. Measuring functional limitations after venous thromboembolism: Optimization of the Post-VTE Functional Status (PVFS) Scale. Thromb Res 2020;190:45-51.

• Nayor M, Short MI, Rasheed H, Lin H, Jonasson C, Yang Q, Hveem K, Felix JF, Morrison AC, Wild PS, Morley MP, Cappola TP, Benson MD, Group CH-HFW, Consortium CH-E, Ngo D, Sinha S, Keyes MJ, Shen D, Wang TJ, Larson MG, Brumpton BM, Gerszten RE, Omland T, Vasan RS. Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits. Circ Heart Fail 2020;13(5):e006749.

• Kaemmerer H, Gorenflo M, Huscher D, Pittrow D, Apitz C, […] Konstantinides S, […] Wilkens H, Wirtz H, Diller GP, Grunig E, Rosenkranz S. Pulmonary Hypertension in Adults with Congenital Heart Disease: Real-World Data from the International COMPERA-CHD Registry. J Clin Med 2020;9(5).

• Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. ERK3/MAPK6 controls IL-8 production and chemotaxis. Elife 2020;9.

• Nickels S, Blom HJ, Schulz A, Joachimsen L, Münzel T, Wild PS, Beutel ME, Blettner M, Lackner KJ, Pfeiffer N, Lagreze WA. No evidence for an association of plasma homocysteine levels and refractive error - Results from the population-based Gutenberg Health Study (GHS). PLoS One 2020;15(4):e0231011.

• Ernst M, Brähler E, Klein EM, Jünger C, Wild PS, Faber J, Schneider A, Beutel ME. What's past is prologue: Recalled parenting styles are associated with childhood cancer survivors' mental health outcomes more than 25 years after diagnosis. Soc Sci Med 2020;252:112916.

• Rezapour J, Schuster AK, Nickels S, Korb CA, Elbaz H, Peto T, Michal M, Münzel T, Wild PS, König J, Lackner K, Schulz A, Pfeiffer N, Beutel ME. Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort. Sci Rep 2020;10(1):4816.

• Lauterbach M, Uhrich E, Eggebrecht L, Göbel S, Panova-Noeva M, Nagler M, Ten Cate V, Bickel C, Espinola-Klein C, Münzel T, Wild PS, Prochaska JH. Specialized Management of Oral Anticoagulation Therapy Improves Outcome in Patients with Chronic Renal Insufficiency. J Clin Med 2020;9(3).

• White RJ, Jerjes-Sanchez C, Bohns Meyer GM, Pulido T, Sepulveda P, Wang KY, Grunig E, Hiremath S, Yu Z, Gangcheng Z, Yip WLJ, Zhang S, Khan A, Deng CQ, Grover R, Tapson VF, Freedom-Ev Investigators. Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial. Am J Respir Crit Care Med 2020;201(6):707-717.

• Ernst M, Brähler E, Wild PS, Faber J, Merzenich H, Beutel ME. The desire for children among adult survivors of childhood cancer: Psychometric evaluation of a cancer-specific questionnaire and relations with sociodemographic and psychological characteristics. Psychooncology 2020;29(3):485-492.

• Schuster AK, Kluck AK, Korb CA, Stoffelns B, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N. Characteristics and pathologies of the vitreo-macular interface-results from the Gutenberg Health Study. Acta Ophthalmol 2020;98(3):e273-e281.

• Keller K, Hobohm L, Wenzel P, Münzel T, Espinola-Klein C, Ostad MA. Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients. Heart Rhythm 2020;17(3):383-390. 

• Barco S, Mahmoudpour SH, Valerio L, Klok FA, Münzel T, Middeldorp S, Ageno W, Cohen AT, Hunt BJ, Konstantinides SV. Trends in mortality related to pulmonary embolism in the European Region, 2000-15: analysis of vital registration data from the WHO Mortality Database. Lancet Respir Med 2020;8(3):277-287.

• Todorov H, Kollar B, Bayer F, Brandao I, Mann A, Mohr J, Pontarollo G, Formes H, Stauber R, Kittner JM, Endres K, Watzer B, Nockher WA, Sommer F, Gerber S, Reinhardt C. alpha-Linolenic Acid-Rich Diet Influences Microbiota Composition and Villus Morphology of the Mouse Small Intestine. Nutrients 2020;12(3).

• Amezquita RA, Lun ATL, Becht E, Carey VJ, Carpp LN, Geistlinger L, Marini F, Rue-Albrecht K, Risso D, Soneson C, Waldron L, Pages H, Smith ML, Huber W, Morgan M, Gottardo R, Hicks SC. Orchestrating single-cell analysis with Bioconductor. Nat Methods 2020;17(2):137-145.

• Schuster AK, Leuschner A, Feretos C, Blumenstein P, Troebs SO, Schwuchow S, Schulz A, Nickels S, Mirshahi A, Blettner M, Beutel ME, Lackner KJ, Münzel T, Pfeiffer N, Wild PS. Choroidal thickness is associated with cardiovascular risk factors and cardiac health: the Gutenberg Health Study. Clin Res Cardiol 2020;109(2):172-182.

• Hampel U, Schuster AK, Nickels S, Schulz A, Lackner KJ, Münzel T, Wild PS, Beutel M, Schmidtmann I, Pfeiffer N. Schirmer test results: are they associated with topical or systemic medication? Ocul Surf 2020;18(1):141-147.

• Helmstädter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Kröller-Schön S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Münzel T, Daiber A, Steven S. Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension. Arterioscler Thromb Vasc Biol 2020;40(1):145-158.

• Gresele P, Orsini S, Noris P, Falcinelli E, Alessi MC, Bury L, Borhany M, Santoro C, Glembotsky AC, Cid AR, Tosetto A, De Candia E, Fontana P, Guglielmini G, Pecci A, Bat-Val study investigators. Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC. J Thromb Haemost 2020;18(3):732-739. 

• Hollerbach A, Müller-Calleja N, Canisius A, Orning C, Lackner KJ. Induction of tissue factor expression by anti-beta2-glycoprotein I is mediated by tumor necrosis factor alpha. J Thromb Thrombolysis 2020;49(2):228-234.

• Mufazalov IA, Andruszewski D, Schelmbauer C, Heink S, Blanfeld M, Masri J, Tang Y, Schüler R, Eich C, Wunderlich FT, Karbach SH, Bluestone JA, Korn T, Waisman A. Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R alpha-Chain Expression. J Immunol 2020;204(4):747-751.

• Ernst M, Brähler E, Wild PS, Jünger C, Faber J, Schneider A, Beutel ME. Risk factors for suicidal ideation in a large, registry-based sample of adult long-term childhood cancer survivors. J Affect Disord 2020;265:351-356.

• Burghardt J, Tibubos AN, Otten D, Brähler E, Binder H, Grabe H, Kruse J, Ladwig KH, Schomerus G, Wild PS, Beutel ME. A multi-cohort consortium for GEnder-Sensitive Analyses of mental health trajectories and implications for prevention (GESA) in the general population in Germany. BMJ Open 2020;10(2):e034220.

• Münzel T, Steven S, Hahad O, Daiber A. The sixth sense is involved in noise-induced stress responses and vascular inflammation: evidence for heightened amygdalar activity in response to transport noise in man. Eur Heart J 2020;41(6):783-785.

• Kumm EJ, Pagel O, Gambaryan S, Walter U, Zahedi RP, Smolenski A, Jurk K. The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets. Cells 2020;9(2).

• Efentakis P, Varela A, Chavdoula E, Sigala F, Sanoudou D, Tenta R, Gioti K, Kostomitsopoulos N, Papapetropoulos A, Tasouli A, Farmakis D, Davos CH, Klinakis A, Suter T, Cokkinos DV, Iliodromitis EK, Wenzel P, Andreadou I. Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy. Cardiovasc Res 2020;116(3):576-591.

• Chen W, Werner F, Illerhaus A, Knopp T, Völker K, Potapenko T, Hofmann U, Frantz S, Baba HA, Rösch M, Zernecke A, Karbach S, Wenzel P, Kuhn M. Stabilization of Perivascular Mast Cells by Endothelial CNP (C-Type Natriuretic Peptide). Arterioscler Thromb Vasc Biol 2020;40(3):682-696.

• Meyer M, Wild J, Hirschmann M, Dimitriadis Z, Münzel T, Gori T, Wenzel P. Predictors for Target Vessel Failure after Recanalization of Chronic Total Occlusions in Patients Undergoing Surveillance Coronary Angiography. J Clin Med 2020;9(1).

• Witkowski M, Witkowski M, Saffarzadeh M, Friebel J, Tabaraie T, Ta Bao L, Chakraborty A, Dorner A, Stratmann B, Tschoepe D, Winter SJ, Krueger A, Ruf W, Landmesser U, Rauch U. Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes. Cardiovasc Diabetol 2020;19(1):20.

• Krieg VJ, Hobohm L, Liebetrau C, Guth S, Kölmel S, Troidl C, Mayer E, Konstantinides SV, Wiedenroth CB, Lankeit M. Risk factors for chronic thromboembolic pulmonary hypertension - Importance of thyroid disease and function. Thromb Res 2020;185:20-26.

• Keller K, Hobohm L, Ebner M, Kresoja KP, Münzel T, Konstantinides SV, Lankeit M. Trends in thrombolytic treatment and outcomes of acute pulmonary embolism in Germany. Eur Heart J 2020;41(4):522-529.

• Ebner M, Kresoja KP, Keller K, Hobohm L, Rogge NIJ, Hasenfuss G, Pieske B, Konstantinides SV, Lankeit M. Temporal trends in management and outcome of pulmonary embolism: a single-centre experience. Clin Res Cardiol 2020;109(1):67-77.

• Bochenek ML, Leidinger C, Rosinus NS, Gogiraju R, Guth S, Hobohm L, Jurk K, Mayer E, Münzel T, Lankeit M, Bosmann M, Konstantinides S, Schäfer K. Activated Endothelial TGFbeta1 Signaling Promotes Venous Thrombus Nonresolution in Mice Via Endothelin-1: Potential Role for Chronic Thromboembolic Pulmonary Hypertension. Circ Res 2020;126(2):162-181.

• Ebner M, Rogge NIJ, Parwani AS, Sentler C, Lerchbaumer MH, Pieske B, Konstantinides SV, Hasenfuss G, Wachter R, Lankeit M. Atrial fibrillation is frequent but does not affect risk stratification in pulmonary embolism. J Intern Med 2020;287(1):100-113.

• Barco S, Schmidtmann I, Ageno W, Bauersachs RM, Becattini C, Bernardi E, Beyer-Westendorf J, Bonacchini L, Brachmann J, Christ M, Czihal M, Duerschmied D, Empen K, Espinola-Klein C, Ficker JH, Fonseca C, Genth-Zotz S, Jimenez D, Harjola VP, Held M, Iogna Prat L, Lange TJ, Manolis A, Meyer A, Mustonen P, Rauch-Kroehnert U, Ruiz-Artacho P, Schellong S, Schwaiblmair M, Stahrenberg R, Westerweel PE, Wild PS, Konstantinides SV, Lankeit M, HoT-PE Investigators. Early discharge and home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban: an international multicentre single-arm clinical trial. Eur Heart J 2020;41(4):509-518.

• Barco S, Klok FA, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Simonneau G, Delcroix M, Lang IM. Sex-specific differences in chronic thromboembolic pulmonary hypertension. Results from the European CTEPH registry. J Thromb Haemost 2020;18(1):151-161.

Reviews 2020

• Wild J, Wegner J, Karbach S. Von der Haut zum Gefäßsystem – Psoriasis und das kardiovaskuläre Risiko. Der Kardiologe 14, 205–211.

• Escher R, Breakey N, Lämmle B. Severe COVID-19 infection associated with endothelial activation. Thromb Res 2020;190:62.

• Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Giri J, Cushman M, Quere I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Caprini JA, Tafur AJ, Burton JR, Francese DP, Wang EY, Falanga A, McLintock C, Hunt BJ, Spyropoulos AC, Barnes GD, Eikelboom JW, Weinberg I, Schulman S, Carrier M, Piazza G, Beckman JA, Steg PG, Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM, Konstantinides SV, Weitz JI, Lip GYH, Global Covid-19 Thrombosis Collaborative Group EbtINE, the Iua SbtESCWGoPC, Right Ventricular F. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review. J Am Coll Cardiol 2020;75(23):2950-2973.

• Ebner M, Lankeit M. [Update diagnosis and therapeutic management of pulmonary embolism]. Dtsch Med Wochenschr 2020;145(11):710-715.

• Nourse J, Spada S, Danckwardt S. Emerging Roles of RNA 3'-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules 2020;10(6). 

• Kiouptsi K, Reinhardt C. Physiological Roles of the von Willebrand Factor-Factor VIII Interaction. Subcell Biochem 2020;94:437-464.

• Lutz J, Jurk K. Platelets in Advanced Chronic Kidney Disease: Two Sides of the Coin. Semin Thromb Hemost 2020;46(3):342-356.

• Stakos D, Skendros P, Konstantinides S, Ritis K. Traps N' Clots: NET-Mediated Thrombosis and Related Diseases. Thromb Haemost 2020;120(3):373-383.

• Barco S, Sebastian T. Death from, with, and without pulmonary embolism. Eur J Intern Med 2020;73:25-26.

• Ward CM, Andrews RK, ISTH State of the Art Speakers. Illustrated State-of-the-Art Capsules of the ISTH 2019 Congress in Melbourne, Australia. Res Pract Thromb Haemost 2019;3(3):431-497.

• Pontarollo G, Mann A, Brandao I, Malinarich F, Schöpf M, Reinhardt C. Protease-activated receptor signaling in intestinal permeability regulation. FEBS J 2020;287(4):645-658.

• Pontarollo G, Kiouptsi K, Reinhardt C. A holobiont view on thrombosis: unravelling the microbiota's influence on arterial thrombus growth. Microb Cell 2020;7(1):28-31.

• Meyer G, Konstantinides S. Should oral anticoagulation be discontinued after 3 months in the setting of a first high-risk pulmonary embolism secondary to a major transient/reversible risk factor? Eur Respir J 2020;55(1).

• Pruszczyk P, Konstantinides S. Where to treat patients with acute pulmonary embolism? Kardiol Pol 2020;78(1):15-19.

Editorials und Fachbeiträge 2020

• Barco S, Münger M, Sebastian T, Kucher N. Reperfusion treatment for high-risk pulmonary embolism associated with COVID-19. Vasa 2020;49(4):257-258.

• Konstantinides S, Lankeit M, Erbel C, Tiefenbacher C. Comments on the guidelines (2019) of the European Society of Cardiology on the management of acute pulmonary embolism With the collaboration of the European Respiratory Society (ERS). European Society of Cardiology zum Management der akuten Lungenembolie. Kardiologe (2020). doi.org/10.1007/s12181-020-00389-x  

• Wild PS, Dimmeler S, Eschenhagen T. An epidemiological study exploring a possible impact of treatment with ACE inhibitors or angiotensin receptor blockers on ACE2 plasma concentrations. J Mol Cell Cardiol 2020;141:108-109.

• Konstantinides SV. The optimal imaging test for diagnosis of acute pulmonary embolism: a second chance for lung scintigraphy? Eur Respir J 2020;55(6).

• Escher R, Breakey N, Lämmle B. ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients. Thromb Res 2020;192:174-175.

• Tziakas DN, Pavlaki M, Chalikias G, Konstantinides SV, Schäfer K. Letter by Tziakas et al Regarding Article, "Aortic Valve Stenosis: From Basic Mechanisms to Novel Therapeutic Targets". Arterioscler Thromb Vasc Biol 2020;40(6):e180-e181.

• Konstantinides SV. Chronic thromboembolic disease following pulmonary embolism: more work ahead. Eur Respir J 2020;55(4).

• Ruf W. TRIF turns the switch for DIC in sepsis. Blood 2020;135(14):1073-1074.

• Barco S, Konstantinides SV. Predicting Venous Thromboembolism in Primary Care. Thromb Haemost 2020;120(4):531-533.

• d'Alessandro E, Becker C, Bergmeier W, Bode C, Bourne JH, Brown H, Buller HR, Ten Cate-Hoek AJ, Ten Cate V, van Cauteren YJM, Cheung YFH, Cleuren A, Coenen D, Crijns H, de Simone I, Dolleman SC, Klein CE, Fernandez DI, Granneman L, van THA, Henke P, Henskens YMC, Huang J, Jennings LK, Jooss N, Karel M, van den Kerkhof D, Klok FA, Kremers B, Lämmle B, Leader A, Lundstrom A, Mackman N, Mannucci PM, Maqsood Z, van der Meijden PEJ, van Moorsel M, Moran LA, Morser J, van Mourik M, Navarro S, Neagoe RAI, Olie RH, van Paridon P, Posma J, Provenzale I, Reitsma PH, Scaf B, Schurgers L, Seelig J, Siegbahn A, Siegerink B, Soehnlein O, Soriano EM, Sowa MA, Spronk HMH, Storey RF, Tantiwong C, Veninga A, Wang X, Watson SP, Weitz J, Zeerleder SS, Ten Cate H, Scientific Reviewer C. Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2020;120(4):538-564.

• Coppo P, Lämmle B. Animal models of thrombotic thrombocytopenic purpura: the tales from zebrafish. Haematologica 2020;105(4):861-863.

• Konstantinides S. 2019 ESC guidelines on pulmonary embolism: Novelties and unanswered questions. Eur J Intern Med 2020;74:1-4.

• Knopp T, Karbach S, Wenzel P. Myeloid Cells to the Rescue: Improving Thrombus Resolution. Thromb Haemost 2020;120(2):197-198.

• Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ni Ainle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, ESC Scientific Document Group. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J 2020;41(4):543-603.

Originalartikel 2019

• Beutel ME, Brähler E, Wiltink J, Kerahrodi JG, Burghardt J, Michal M, Schulz A, Wild PS, Münzel T, Schmidtmann I, Lackner KJ, Pfeiffer N, Borta A, Tibubos AN. New onset of depression in aging women and men: contributions of social, psychological, behavioral, and somatic predictors in the community. Psychol Med 2019;49(7):1148-1155.

• Kozhuharov N, Goudev A, Flores D, [...], Wenzel P, [...], Münzel T, Erne P, Mueller C, GALACTIC Investigators. Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure: The GALACTIC Randomized Clinical Trial. JAMA 2019;322(23):2292-2302.

• Fiess A, Elbaz H, Korb CA, Nickels S, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Peto T, Pfeiffer N, Schuster AK. Low Birth Weight Is Linked to Age-Related Macular Degeneration: Results From the Population-Based Gutenberg Health Study (GHS). Invest Ophthalmol Vis Sci 2019;60(14):4943-4950.

• Tibubos AN, Brähler E, Ernst M, Baumgarten C, Wiltink J, Burghardt J, Michal M, Ghaemi Kerahrodi J, Schulz A, Wild PS, Münzel T, Schmidtmann I, Lackner KJ, Pfeiffer N, Borta A, Beutel ME. Course of depressive symptoms in men and women: differential effects of social, psychological, behavioral and somatic predictors. Sci Rep 2019;9(1):18929.

• Ghaemi Kerahrodi J, Brähler E, Wiltink J, Michal M, Schulz A, Wild PS, Münzel T, Toenges G, Lackner KJ, Pfeiffer N, Beutel ME. Association between medicated obstructive pulmonary disease, depression and subjective health: results from the population-based Gutenberg Health Study. Sci Rep 2019;9(1):20252.

• Alflen A, Aranda Lopez P, Hartmann AK, Maxeiner J, Bosmann M, Sharma A, Platten J, Ries F, Beckert H, Ruf W, Radsak MP. Neutrophil extracellular traps impair fungal clearance in a mouse model of invasive pulmonary aspergillosis. Immunobiology 2019:151867.

• Brunner FJ, Waldeyer C, Ojeda F, Salomaa V, Kee F, Sans S, Thorand B, Giampaoli S, Brambilla P, Tunstall-Pedoe H, Moitry M, Iacoviello L, Veronesi G, Grassi G, Mathiesen EB, Soderberg S, Linneberg A, Brenner H, Amouyel P, Ferrieres J, Tamosiunas A, Nikitin YP, Drygas W, Melander O, Jockel KH, Leistner DM, Shaw JE, Panagiotakos DB, Simons LA, Kavousi M, Vasan RS, Dullaart RPF, Wannamethee SG, Riserus U, Shea S, de Lemos JA, Omland T, Kuulasmaa K, Landmesser U, Blankenberg S, Multinational Cardiovascular Risk Consortium. Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium. Lancet 2019;394(10215):2173-2183.

• Makhoul S, Dörschel S, Gambaryan S, Walter U, Jurk K. Feedback Regulation of Syk by Protein Kinase C in Human Platelets. Int J Mol Sci 2019;21(1).

• Schütz E, Gogiraju R, Pavlaki M, Drosos I, Georgiadis GS, Argyriou C, Rim Ben Hallou A, Konstantinou F, Mikroulis D, Schüler R, Bochenek ML, Gachkar S, Buschmann K, Lankeit M, Karbach SH, Münzel T, Tziakas D, Konstantinides S, Schäfer K. Age-Dependent and -Independent Effects of Perivascular Adipose Tissue and Its Paracrine Activities during Neointima Formation. Int J Mol Sci 2019;21(1).

• Lückel C, Picard F, Raifer H, Campos Carrascosa L, Guralnik A, Zhang Y, Klein M, Bittner S, Steffen F, Moos S, Marini F, Gloury R, Kurschus FC, Chao YY, Bertrams W, Sexl V, Schmeck B, Bonetti L, Grusdat M, Lohoff M, Zielinski CE, Zipp F, Kallies A, Brenner D, Berger M, Bopp T, Tackenberg B, Huber M. IL-17(+) CD8(+) T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis. Nat Commun 2019;10(1):5722. 

• Panova-Noeva M, Wagner B, Nagler M, Arnold N, Prochaska JH, Eckerle S, Spronk HM, Merzenich H, Wingerter A, Schneider A, Danckwardt S, Ten Cate H, Faber J, Wild PS. Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample. Sci Rep 2019;9(1):20090.

• Triantafyllias K, de Blasi M, Lutgendorf F, Cavagna L, Stortz M, Weinmann-Menke J, Konstantinides S, Galle PR, Schwarting A. High cardiovascular risk in mixed connective tissue disease: evaluation of macrovascular involvement and its predictors by aortic pulse wave velocity. Clin Exp Rheumatol 2019;37(6):994-1002.

• Münzel T, Hahad O, Gori T, Hollmann S, Arnold N, Prochaska JH, Schulz A, Beutel M, Pfeiffer N, Schmidtmann I, Lackner KJ, Keaney JF, Jr., Wild PS. Heart rate, mortality, and the relation with clinical and subclinical cardiovascular diseases: results from the Gutenberg Health Study. Clin Res Cardiol 2019;108(12):1313-1323.

• Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B, Nelson CP, Bastiaenen R, De Bortoli M, Rossini A, Deisenhofer I, Stark K, Assa S, Braund PS, Cabrera C, Dominiczak AF, Gogele M, Hall LM, Ikram MA, Kavousi M, Lackner KJ, Lifelines Cohort S, Müller C, Münzel T, Nauck M, Padmanabhan S, Pfeiffer N, Spector TD, Uitterlinden AG, Verweij N, Volker U, Warren HR, Zafar M, Felix SB, Kors JA, Snieder H, Munroe PB, Pattaro C, Fuchsberger C, Schmidt G, Nolte IM, Schunkert H, Pramstaller PP, Wild PS, van der Harst P, Stricker BH, Schnabel RB, Samani NJ, Hengstenberg C, Dorr M, Behr ER, Reinhard W. KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI Insight 2019;4(23).

• Sebastian T, Spirk D, Engelberger RP, Dopheide JF, Baumann FA, Barco S, Spescha R, Leeger C, Kucher N. Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome. Thromb Haemost 2019;119(12):2064-2073.

• Makhoul S, Panova-Noeva M, Regnault V, Ruf W, Wenzel P, Lagrange J. Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography. J Clin Med 2019;8(11).

• Elflein HM, Schuster AK, Pitz S, Hardt J, Nickels S, Münzel T, Wild PS, Beutel ME, Blettner M, Lackner KJ, Pfeiffer N, Unterrainer JM. Intact Visuospatial Cognition in Amblyopia: Results From the Gutenberg Health Study. J Pediatr Ophthalmol Strabismus 2019;56(6):397-401.

• Labenz C, Prochaska JH, Huber Y, Nagel M, Straub BK, Wild P, Galle PR, Schattenberg JM. Cardiovascular Risk Categories in Patients With Nonalcoholic Fatty Liver Disease and the Role of Low-Density Lipoprotein Cholesterol. Hepatol Commun 2019;3(11):1472-1481.

• Kieback AG, Espinola-Klein C, Lamina C, Moebus S, Tiller D, Lorbeer R, Schulz A, Meisinger C, Medenwald D, Erbel R, Kluttig A, Wild PS, Kronenberg F, Kröger K, Ittermann T, Dörr M. One simple claudication question as first step in Peripheral Arterial Disease (PAD) screening: A meta-analysis of the association with reduced Ankle Brachial Index (ABI) in 27,945 subjects. PLoS One 2019;14(11):e0224608.

• Hahad O, Wild PS, Prochaska JH, Schulz A, Hermanns I, Lackner KJ, Pfeiffer N, Schmidtmann I, Beutel M, Gori T, Deanfield JE, Münzel T. Endothelial Function Assessed by Digital Volume Plethysmography Predicts the Development and Progression of Type 2 Diabetes Mellitus. J Am Heart Assoc 2019;8(20):e012509.

• Lowres N, Olivier J, Chao TF, Chen SA, Chen Y, Diederichsen A, Fitzmaurice DA, Gomez-Doblas JJ, Harbison J, Healey JS, Hobbs FDR, Kaasenbrood F, Keen W, Lee VW, Lindholt JS, Lip GYH, Mairesse GH, Mant J, Martin JW, Martin-Rioboo E, McManus DD, Muniz J, Münzel T, Nakamya J, Neubeck L, Orchard JJ, Perula de Torres LA, Proietti M, Quinn FR, Roalfe AK, Sandhu RK, Schnabel RB, Smyth B, Soni A, Tieleman R, Wang J, Wild PS, Yan BP, Freedman B. Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals. PLoS Med 2019;16(9):e1002903.

• Ernst M, Wiltink J, Tibubos AN, Brähler E, Schulz A, Wild PS, Burghardt J, Münzel T, König J, Lackner K, Pfeiffer N, Michal M, Beutel ME. Linking cancer and mental health in men and women in a representative community sample. J Psychosom Res 2019;124:109760.

• Neumann JT, Twerenbold R, Ojeda F, Sorensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jorgensen T, Soderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renne T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S. Application of High-Sensitivity Troponin in Suspected Myocardial Infarction. N Engl J Med 2019;380(26):2529-2540.

• Schlax J, Jünger C, Beutel ME, Münzel T, Pfeiffer N, Wild P, Blettner M, Kerahrodi JG, Wiltink J, Michal M. Income and education predict elevated depressive symptoms in the general population: results from the Gutenberg health study. BMC Public Health 2019;19(1):430.

• Herzog J, Schmidt FP, Hahad O, Mahmoudpour SH, Mangold AK, Garcia Andreo P, Prochaska J, Koeck T, Wild PS, Sorensen M, Daiber A, Münzel T. Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects. Basic Res Cardiol 2019;114(6):46.

• Fujimura Y, Lämmle B, Tanabe S, Sakai K, Kimura T, Kokame K, Miyata T, Takahashi Y, Taniguchi S, Matsumoto M. Patent ductus arteriosus generates neonatal hemolytic jaundice with thrombocytopenia in Upshaw-Schulman syndrome. Blood Adv 2019;3(21):3191-3195.

• Makhoul S, Trabold K, Gambaryan S, Tenzer S, Pillitteri D, Walter U, Jurk K. cAMP- and cGMP-elevating agents inhibit GPIbalpha-mediated aggregation but not GPIbalpha-stimulated Syk activation in human platelets. Cell Commun Signal 2019;17(1):122.

• Elbaz H, Schulz A, Ponto KA, Nickels S, Pfeiffer N, Mirshahi A, Peto T. Posterior segment eye lesions: prevalence and associations with ocular and systemic parameters: results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 2019;257(10):2127-2135.

• Wild J, Schüler R, Knopp T, Molitor M, Kossmann S, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH. Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation. Int J Mol Sci 2019;20(17).

• Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Roth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M. Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology. Nat Commun 2019;10(1):4877.

• Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. MBio 2019;10(5).

• Müller-Calleja N, Hollerbach A, Ritter S, Pedrosa DG, Strand D, Graf C, Reinhardt C, Strand S, Poncelet P, Griffin JH, Lackner KJ, Ruf W. Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis. Blood 2019;134(14):1119-1131.

• Grothusen C., Lankeit M., Olsson K., Panholzer B., Haneya A., Cremer J. Acute pulmonary embolism. Diagnostics and treatment including surgical treatment options. ZEITSCHRIFT FUR HERZ THORAX UND GEFASSCHIRURGIE. 2019; 33(1): 25-39.

• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C, Lavie CJ, Konstantinides S, Lankeit M. Survival Benefit of Obese Patients With Pulmonary Embolism. Mayo Clin Proc 2019;94(10):1960-1973.

• Keller K, Tesche C, Gerhold-Ay A, Nickels S, Klok FA, Rappold L, Hasenfuss G, Dellas C, Konstantinides SV, Lankeit M. Quality of life and functional limitations after pulmonary embolism and its prognostic relevance. J Thromb Haemost 2019;17(11):1923-1934.

• Klingenberg R, Schlager O, Limacher A, Mean M, Vuilleumier N, Beer JH, Staub D, Frauchiger B, Aschwanden M, Lämmle B, Righini M, Egloff M, Osterwalder J, Angelillo-Scherrer A, Kucher N, Banyai M, Rodondi N, von Eckardstein A, Aujesky D, Husmann M, Matter CM. Risk stratification of elderly patients with acute pulmonary embolism. Eur J Clin Invest 2019;49(9):e13154.

• Haub J, Roehrig N, Uhrin P, Schabbauer G, Eulberg D, Melchior F, Shahneh F, Probst HC, Becker C, Steinbrink K, Raker VK. Intervention of Inflammatory Monocyte Activity Limits Dermal Fibrosis. J Invest Dermatol 2019;139(10):2144-2153.

• Finger S, Knorr M, Molitor M, Schüler R, Garlapati V, Waisman A, Brandt M, Münzel T, Bopp T, Kossmann S, Karbach S, Wenzel P. A sequential interferon gamma directed chemotactic cellular immune response determines survival and cardiac function post-myocardial infarction. Cardiovasc Res 2019;115(13):1907-1917.

• Ten Cate V, Nagler M, Panova-Noeva M, Eggebrecht L, Arnold N, Lamparter H, Hermanns MI, Ten Cate H, Prins MH, Espinola-Klein C, Münzel T, Lackner KJ, Wild PS, Prochaska JH. The diagnostic performance of renal function-adjusted D-dimer testing in individuals suspected of having venous thromboembolism. Haematologica 2019;104(9):e424-e427.

• Trenkwalder T, Rübsamen N, Schmitt VH, Arnold N, Kaess BM, Sinning CR, Zeller T, Beutel ME, Schmidtmann I, Nickels S, Pfeiffer N, Leuschner A, Münzel T, Lackner KJ, Hengstenberg C, Blankenberg S, Wild PS, Reinhard W, Schnabel R. Left ventricular geometry and function in early repolarization: results from the population-based Gutenberg Health Study. Clin Res Cardiol 2019;108(10):1107-1116.

• van Dorland HA, Taleghani MM, Sakai K, Friedman KD, George JN, Hrachovinova I, Knobl PN, von Krogh AS, Schneppenheim R, Aebi-Huber I, Butikofer L, Largiader CR, Cermakova Z, Kokame K, Miyata T, Yagi H, Terrell DR, Vesely SK, Matsumoto M, Lämmle B, Fujimura Y, Kremer Hovinga JA, Hereditary TTP Registry. The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017. Haematologica 2019;104(10):2107-2115.

• Schmidtmann I, Konstantinides S, Binder H. Power of the Wilcoxon-Mann-Whitney test for non-inferiority in the presence of death-censored observations. Biom J 2019;61(5):1187-1200.

• Keller K, Hobohm L, Geyer M, Münzel T, Lavie CJ, Ostad MA, Espinola-Klein C. Obesity paradox in peripheral artery disease. Clin Nutr 2019;38(5):2269-2276.

• Keller K, Hobohm L, Münzel T, Ostad MA. Sex-specific differences regarding seasonal variations of incidence and mortality in patients with myocardial infarction in Germany. Int J Cardiol 2019;287:132-138.

• Ernst M, Brähler E, Klein EM, Jünger C, Wild PS, Faber J, Schneider A, Beutel ME. Parenting in the face of serious illness: Childhood cancer survivors remember different rearing behavior than the general population. Psychooncology 2019;28(8):1663-1670.

• von Jeinsen B, Liebetrau C, Palapies L, Tzikas S, Zeller T, Bickel C, Schmidt A, Tubaro M, Lackner KJ, Sar F, Baldus S, Zeiher AM, Blankenberg S, Gori T, Münzel T, Hamm CW, Wild PS, Keller T. Identification of acute myocardial infarction in elderly patients using optimized highly sensitive troponin I thresholds. Biomarkers 2019;24(6):549-555.

• Althaus K, Zieger B, Bakchoul T, Jurk K. Standardization of Light Transmission Aggregometry for Diagnosis of Platelet Disorders: An Inter-Laboratory External Quality Assessment. Thromb Haemost 2019;119(7):1154-1161.

• Duhme C, Lehwald N, Kehrel BE, Bauchrowitz E, Ngepi A, Schmelzle M, Kolokotronis T, Benhidjeb T, Krüger M, Jurk K, Knoefel WT, Robson SC, Schulte Am Esch J. CD133(+) bone marrow stem cells (BMSC) control platelet activation - Role of ectoNTPDase-1 (CD39). Blood Cells Mol Dis 2019;77:142-148.

• Hollerbach A, Müller-Calleja N, Ritter S, Häuser F, Canisius A, Orning C, Jurk K, Lackner KJ. Platelet Activation by Antiphospholipid Antibodies Depends on Epitope Specificity and is Prevented by mTOR Inhibitors. Thromb Haemost 2019;119(7):1147-1153.

• Trabold K, Makhoul S, Gambaryan S, van Ryn J, Walter U, Jurk K. The Direct Thrombin Inhibitors Dabigatran and Lepirudin Inhibit GPIbalpha-Mediated Platelet Aggregation. Thromb Haemost 2019;119(6):916-929.

• Ponto KA, Scharrer I, Binder H, Korb C, Rosner AK, Ehlers TO, Rieser N, Grübel NC, Rossmann H, Wild PS, Feltgen N, Pfeiffer N, Mirshahi A. Hypertension and multiple cardiovascular risk factors increase the risk for retinal vein occlusions: results from the Gutenberg Retinal Vein Occlusion Study. J Hypertens 2019;37(7):1372-1383.

• Verma D, Kumar R, Pereira RS, Karantanou C, Zanetti C, Minciacchi VR, Fulzele K, Kunz K, Hoelper S, Zia-Chahabi S, Jabagi MJ, Emmerich J, Dray-Spira R, Kuhlee F, Hackmann K, Schroeck E, Wenzel P, Müller S, Filmann N, Fontenay M, Pajevic PD, Krause DS. Vitamin K antagonism impairs the bone marrow microenvironment and hematopoiesis. Blood 2019;134(3):227-238.

• Hobohm L, von Bardeleben RS, Ostad MA, Wenzel P, Münzel T, Gori T, Keller K. 5-Year Experience of In-Hospital Outcomes After Percutaneous Left Atrial Appendage Closure in Germany. JACC Cardiovasc Interv 2019;12(11):1044-1052.

• Schüler R, Efentakis P, Wild J, Lagrange J, Garlapati V, Molitor M, Kossmann S, Oelze M, Stamm P, Li H, Schäfer K, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH. T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of (.)NO/cGMP Signaling. Oxid Med Cell Longev 2019;2019:6721531.

• Koizume S, Takahashi T, Yoshihara M, Nakamura Y, Ruf W, Takenaka K, Miyagi E, Miyagi Y. Cholesterol Starvation and Hypoxia Activate the FVII Gene via the SREBP1-GILZ Pathway in Ovarian Cancer Cells to Produce Procoagulant Microvesicles. Thromb Haemost 2019;119(7):1058-1071. 

• Ten Cate V, Koeck T, Panova-Noeva M, Rapp S, Prochaska JH, Lenz M, Schulz A, Eggebrecht L, Hermanns MI, Heitmeier S, Krahn T, Laux V, Münzel T, Leineweber K, Konstantinides SV, Wild PS, Collaborators: Investigators FBS, Study VT. A prospective cohort study to identify and evaluate endotypes of venous thromboembolism: Rationale and design of the Genotyping and Molecular Phenotyping in Venous ThromboEmbolism project (GMP-VTE). Thromb Res 2019;181:84-91.

• Valerio L, Ambaglio C, Barone M, Ciola M, Konstantinides SV, Mahmoudpour SH, Picchi C, Pieresca C, Trinchero A, Barco S. Recurrence Risk after First Symptomatic Distal versus Proximal Deep Vein Thrombosis According to Baseline Risk Factors. TH Open 2019;3(1):e58-e63. 

• Kölmel S, Hobohm L, Käberich A, Krieg VJ, Bochenek ML, Wenzel P, Wiedenroth CB, Liebetrau C, Hasenfuss G, Mayer E, Konstantinides SV, Schäfer K, Guth S, Lankeit M. Potential Involvement of Osteopontin in Inflammatory and Fibrotic Processes in Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension. Thromb Haemost 2019;119(8):1332-1346.

• Prochaska JH, Hausner C, Nagler M, Göbel S, Eggebrecht L, Panova-Noeva M, Arnold N, Lauterbach M, Bickel C, Michal M, Hardt R, Espinola-Klein C, Lackner KJ, Münzel T, Wild PS. Subtherapeutic Anticoagulation Control under Treatment with Vitamin K-Antagonists-Data from a Specialized Coagulation Service. Thromb Haemost 2019;119(8):1347-1357.

• Fiess A, Schuster AK, Nickels S, Urschitz MS, Elflein HM, Schulz A, Münzel T, Wild PS, Beutel ME, Schmidtmann I, Lackner KJ, Pfeiffer N. Association of Low Birth Weight With Altered Corneal Geometry and Axial Length in Adulthood in the German Gutenberg Health Study. JAMA Ophthalmol 2019;137(5):507-514.

• Kresoja KP, Ebner M, Rogge NIJ, Sentler C, Keller K, Hobohm L, Hasenfuss G, Konstantinides SV, Pieske B, Lankeit M. Prediction and prognostic importance of in-hospital major bleeding in a real-world cohort of patients with pulmonary embolism. Int J Cardiol 2019;290:144-149.

• Barco S, Russo M, Vicaut E, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Danays T, Dellas C, Duerschmied D, Empen K, Ferrari E, Galie N, Jimenez D, Klok FA, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N, Palazzini M, Pruszczyk P, Rugolotto M, Salvi A, Sanchez O, Schellong S, Sobkowicz B, Meyer G, Konstantinides SV. Incomplete echocardiographic recovery at 6 months predicts long-term sequelae after intermediate-risk pulmonary embolism. A post-hoc analysis of the Pulmonary Embolism Thrombolysis (PEITHO) trial. Clin Res Cardiol 2019;108(7):772-778.

• Eggebrecht L, Prochaska JH, Tröbs SO, Schwuchow-Thonke S, Göbel S, Diestelmeier S, Schulz A, Arnold N, Panova-Noeva M, Koeck T, Rapp S, Gori T, Lackner KJ, Ten Cate H, Münzel T, Wild PS. Direct oral anticoagulants and vitamin K antagonists are linked to differential profiles of cardiac function and lipid metabolism. Clin Res Cardiol 2019;108(7):787-796.

• Drosos I, Pavlaki M, Ortega Carrillo MDP, Kourkouli A, Buschmann K, Konstantinou F, Gogiraju R, Bochenek ML, Chalikias G, Tortopidis C, Vahl CF, Mikroulis D, Tziakas D, Münzel T, Konstantinides S, Schäfer K. Increased Lymphangiogenesis and Lymphangiogenic Growth Factor Expression in Perivascular Adipose Tissue of Patients with Coronary Artery Disease. J Clin Med 2019;8(7).

• Akhtar J, More P, Albrecht S, Marini F, Kaiser W, Kulkarni A, Wojnowski L, Fontaine JF, Andrade-Navarro MA, Silies M, Berger C. TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay. Life Sci Alliance 2019;2(4).

• Marini F, Binder H. pcaExplorer: an R/Bioconductor package for interacting with RNA-seq principal components. BMC Bioinformatics 2019;20(1):331.

• Klok FA, Presles E, Tromeur C, Barco S, Konstantinides SV, Sanchez O, Pernod G, Raj L, Robin P, Le Roux PY, Hoffman C, Melac S, Bertoletti L, Girard P, Laporte S, Mismetti P, Meyer G, Leroyer C, Couturaud F, Investigators P-P. Evaluation of the predictive value of the bleeding prediction score VTE-BLEED for recurrent venous thromboembolism. Res Pract Thromb Haemost 2019;3(3):364-371.

• Keller K, Rappold L, Gerhold-Ay A, Hobohm L, Hasenfuss G, Konstantinides SV, Dellas C, Lankeit M. Sex-specific differences in pulmonary embolism. Thromb Res 2019;178:173-181.

• Koriath M, Müller C, Pfeiffer N, Nickels S, Beutel M, Schmidtmann I, Rapp S, Münzel T, Westermann D, Karakas M, Wild PS, Lackner KJ, Blankenberg S, Zeller T. Relative Telomere Length and Cardiovascular Risk Factors. Biomolecules 2019;9(5).

• Ernst M, Tibubos AN, Unterrainer J, Burghardt J, Brähler E, Wild PS, Jünger C, Faber J, Schneider A, Beutel ME. Status and predictors of planning ability in adult long-term survivors of CNS tumors and other types of childhood cancer. Sci Rep 2019;9(1):7290.

• Mahmoudpour SH, Jankowski M, Valerio L, Becker C, Espinola-Klein C, Konstantinides S, Quitzau K, Barco S. Safety of low-dose subcutaneous recombinant interleukin-2: systematic review and meta-analysis of randomized controlled trials. Sci Rep 2019;9(1):7145.

• Keller K, Hobohm L, Engelhardt M. Risk of venous thromboembolism after endoprosthetic surgeries: lower versus upper extremity endoprosthetic surgeries. Heart Vessels 2019;34(5):815-823.

• Unterrainer JM, Rahm B, Kaller CP, Wild PS, Münzel T, Blettner M, Lackner K, Pfeiffer N, Beutel ME. Assessing Planning Ability Across the Adult Life Span in a Large Population-Representative Sample: Reliability Estimates and Normative Data for the Tower of London (TOL-F) Task. J Int Neuropsychol Soc 2019;25(5):520-529.

• van Geffen JP, Brouns SLN, Batista J, McKinney H, Kempster C, Nagy M, Sivapalaratnam S, Baaten C, Bourry N, Frontini M, Jurk K, Krause M, Pillitteri D, Swieringa F, Verdoold R, Cavill R, Kuijpers MJE, Ouwehand WH, Downes K, Heemskerk JWM. High-throughput elucidation of thrombus formation reveals sources of platelet function variability. Haematologica 2019;104(6):1256-1267.

• Jäger M, Hubert A, Gogiraju R, Bochenek ML, Münzel T, Schäfer K. Inducible Knockdown of Endothelial Protein Tyrosine Phosphatase-1B Promotes Neointima Formation in Obese Mice by Enhancing Endothelial Senescence. Antioxid Redox Signal 2019;30(7):927-944.

• Keller K, Hobohm L, Münzel T, Ostad MA. Syncope in the German Nationwide inpatient sample - Syncope in atrial fibrillation/flutter is related to pulmonary embolism and is accompanied by higher in-hospital mortality. Eur J Intern Med 2019;62:29-36.

• Burghardt J, Klein E, Brähler E, Ernst M, Schneider A, Eckerle S, Neu MA, Wingerter A, Henninger N, Panova‐Noeva M, Prochaska J, Wild P, Beutel M, Faber J. Prevalence of mental distress among adult survivors of childhood cancer in Germany—Compared to the general population. Cancer Medicine 2019;8(4):1865-1874.

• Hansen M, Peltier J, Killy B, Amin B, Bodendorfer B, Hartlova A, Uebel S, Bosmann M, Hofmann J, Buttner C, Ekici AB, Kuttke M, Franzyk H, Foged C, Beer-Hammer S, Schabbauer G, Trost M, Lang R. Macrophage Phosphoproteome Analysis Reveals MINCLE-dependent and -independent Mycobacterial Cord Factor Signaling. Mol Cell Proteomics 2019;18(4):669-685.

• Rothmeier AS, Versteeg HH, Ruf W. Factor VIIa-induced interaction with integrin controls the release of tissue factor on extracellular vesicles from endothelial cells. J Thromb Haemost 2019;17(4):627-634.

• Tziakas DN, Chalikias G, Pavlaki M, Kareli D, Gogiraju R, Hubert A, Bohm E, Stamoulis P, Drosos I, Kikas P, Mikroulis D, Giatromanolaki A, Georgiadis GS, Konstantinou F, Argyriou C, Münzel T, Konstantinides SV, Schäfer K. Lysed Erythrocyte Membranes Promote Vascular Calcification. Circulation 2019;139(17):2032-2048.

• von Bardeleben RS, Hobohm L, Kreidel F, Ostad MA, Schulz E, Konstantinides S, Lankeit M, Feldman T, Münzel T, Keller K. Incidence and in-hospital safety outcomes of patients undergoing percutaneous mitral valve edge-to-edge repair using MitraClip: five-year German national patient sample including 13,575 implants. EuroIntervention 2019;14(17):1725-1732.

• Barco S, Granziera S, Coppens M, Douxfils J, Nijkeuter M, Riva N, Vanassche T, Zhang G, Lin M, Kamphuisen PW, Cohen AT, Beyer-Westendorf J. Determinants of the Quality of Warfarin Control after Venous Thromboembolism and Validation of the SAMe-TT2-R2 Score: An Analysis of Hokusai-VTE. Thromb Haemost 2019;119(4):675-684.

• Keller K, Geyer M, Münzel T, Ostad MA, Gori T. Impact of atrial fibrillation on in-hospital mortality of ischemic stroke patients and identification of promoting factors of atrial thrombi - Results from the German nationwide inpatient sample and a single-center retrospective cohort. Medicine (Baltimore) 2019;98(4):e14086.

• Keller K, Hobohm L, Münzel T, Ostad MA. Impact of symptomatic atherosclerosis in patients with pulmonary embolism. Int J Cardiol 2019;278:225-231.

• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C. Impact of chronic obstructive pulmonary disease on the outcomes of patients with peripheral artery disease. Respir Med 2019;147:1-6.

• Beutel ME, Wiltink J, Ghaemi Kerahrodi J, Tibubos AN, Brähler E, Schulz A, Wild P, Münzel T, Lackner K, König J, Pfeiffer N, Michal M, Henning M. Somatic symptom load in men and women from middle to high age in the Gutenberg Health Study - association with psychosocial and somatic factors. Sci Rep 2019;9(1):4610.

• Dörr M, Hamburg NM, Müller C, Smith NL, Gustafsson S, Lehtimäki T, Teumer A, Zeller T, Li X, Lind L, Raitakari OT, Völker U, Blankenberg S, McKnight B, Morris AP, Kähönen M, Lemaitre RN, Wild PS, Nauck M, Völzke H, Münzel T, Mitchell GF, Psaty BM, Lindgren CM, Larson MG, Felix SB, Ingelsson E, Lyytikäinen LP, Herrington D, Benjamin EJ, Schnabel RB. Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation. Circ Genom Precis Med 2019;12(2):e002409.

• Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonovic N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotic A, Jonjic S, Müller M, Strobl B. Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1. Cell Rep 2019;26(9):2394-2406 e2395.

• Sharma A, Steven S, Bosmann M. The pituitary gland prevents shock-associated death by controlling multiple inflammatory mediators. Biochem Biophys Res Commun 2019;509(1):188-193.

• Hewel C, Kaiser J, Wierczeiko A, Linke J, Reinhardt C, Endres K, Gerber S. Common miRNA Patterns of Alzheimer's Disease and Parkinson's Disease and Their Putative Impact on Commensal Gut Microbiota. Front Neurosci 2019;13:113.

• Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF. Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2. Nat Commun 2019;10(1):1198.

• Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG. Virus envelope tissue factor promotes infection in mice. J Thromb Haemost 2019;17(3):482-491.

• Chalikias G, Serif L, Kikas P, Thomaidis A, Stakos D, Makrygiannis D, Chatzikyriakou S, Papoulidis N, Voudris V, Lantzouraki A, Müller M, Arampatzis S, Konstantinides S, Tziakas D. Long-term impact of acute kidney injury on prognosis in patients with acute myocardial infarction. Int J Cardiol 2019;283:48-54.

• Gogiraju R, Hubert A, Fahrer J, Straub BK, Brandt M, Wenzel P, Münzel T, Konstantinides S, Hasenfuss G, Schäfer K. Endothelial Leptin Receptor Deletion Promotes Cardiac Autophagy and Angiogenesis Following Pressure Overload by Suppressing Akt/mTOR Signaling. Circ Heart Fail 2019;12(1):e005622.

• Kostrubiec M, Plywaczewska M, Jimenez D, Lankeit M, Ciurzynski M, Konstantinides S, Pruszczyk P. The Prognostic Value of Renal Function in Acute Pulmonary Embolism-A Multi-Centre Cohort Study. Thromb Haemost 2019;119(1):140-148.

• Kiouptsi K, Finger S, Garlapati VS, Knorr M, Brandt M, Walter U, Wenzel P, Reinhardt C. Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice. Biol Open 2019;8(1).

• Barco S, Mahmoudpour SH, Planquette B, Sanchez O, Konstantinides SV, Meyer G. Prognostic value of right ventricular dysfunction or elevated cardiac biomarkers in patients with low-risk pulmonary embolism: a systematic review and meta-analysis. Eur Heart J 2019;40(11):902-910.

• Kröller-Schön S, Jansen T, Tran TLP, Kvandova M, Kalinovic S, Oelze M, Keaney JF, Jr., Foretz M, Viollet B, Daiber A, Kossmann S, Lagrange J, Frenis K, Wenzel P, Münzel T, Schulz E. Endothelial alpha1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction. Basic Res Cardiol 2019;114(2):8.

• Schüler R, Brand A, Klebow S, Wild J, Veras FP, Ullmann E, Roohani S, Kolbinger F, Kossmann S, Wohn C, Daiber A, Münzel T, Wenzel P, Waisman A, Clausen BE, Karbach S. Antagonization of IL-17A Attenuates Skin Inflammation and Vascular Dysfunction in Mouse Models of Psoriasis. J Invest Dermatol 2019;139(3):638-647.

• Barco S, Klok FA, Mahe I, Marchena PJ, Ballaz A, Rubio CM, Adarraga MD, Mastroiacovo D, Konstantinides SV, Monreal M, Investigators R. Impact of sex, age, and risk factors for venous thromboembolism on the initial presentation of first isolated symptomatic acute deep vein thrombosis. Thromb Res 2019;173:166-171.

• Klok FA, Pruefer D, Rolf A, Konstantinides SV. Magnetic resonance direct thrombus imaging for pre-operative assessment of acute thrombosis in chronic thromboembolic pulmonary hypertension. Eur Heart J 2019;40(11):944.

• Sacco C, Zane F, Granziera S, Holm K, Creemers-Schild D, Hotz MA, Turpini E, Valentini A, Righini C, Karkos PD, Verhamme P, Di Nisio M, Konstantinides S, Pecci A, Barco S, Lemierre Study G. Lemierre Syndrome: Clinical Update and Protocol for a Systematic Review and Individual Patient Data Meta-analysis. Hamostaseologie 2019;39(1):76-86.

• Prochaska JH, Luther N, Brähler M, Schulz A, Hermanns MI, Lackner KJ, Espinola-Klein C, Münzel T, Wild PS, Becker C. Acute deep vein thrombosis suppresses peripheral T cell effector function. Br J Haematol 2019;184(5):847-850.

• Hain T, Melchior F, Kamenjarin N, Muth S, Weslati H, Clausen BE, Mahnke K, Silva-Vilches C, Schutze K, Sohl J, Radsak MP, Bundgen G, Bopp T, Danckwardt S, Schild H, Probst HC. Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses. J Invest Dermatol 2019;139(2):422-429.

• Bibli SI, Papapetropoulos A, Iliodromitis EK, Daiber A, Randriamboavonjy V, Steven S, Brouckaert P, Chatzianastasiou A, Kypreos KE, Hausenloy DJ, Fleming I, Andreadou I. Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug. Cardiovasc Res 2019;115(3):625-636.

• Börschel CS, Rübsamen N, Ojeda FM, Wild PS, Hoffmann BA, Prochaska JH, Gori T, Lackner KJ, Blankenberg S, Zeller T, Münzel T, Schnabel RB. Noninvasive peripheral vascular function and atrial fibrillation in the general population. J Hypertens 2019;37(5):928-934.

• Panova-Noeva M, Neu MA, Eckerle S, Spix C, Schneider A, Schmidtmann I, Spronk HM, Pfeiffer N, Beutel M, Lackner KJ, Münzel T, Ten Cate H, Merzenich H, Faber J, Wild PS. Cardiovascular risk factors are important determinants of platelet-dependent thrombin generation in adult survivors of childhood cancer. Clin Res Cardiol 2019;108(4):438-447.

• Eggebrecht L, Nagler M, Göbel S, Lamparter H, Keller K, Wagner B, Panova-Noeva M, Ten Cate V, Bickel C, Lauterbach M, Espinola-Klein C, Hardt R, Münzel T, Prochaska JH, Wild PS. Relevance of Polypharmacy for Clinical Outcome in Patients Receiving Vitamin K Antagonists. J Am Geriatr Soc 2019;67(3):463-470.

• Keller K. Life Expectancy of Olympic Wrestling Champions in Comparison to the General Population. J Community Health 2019;44(1):61-67.

Reviews 2019

• Lässiger-Herfurth A, Pontarollo G, Grill A, Reinhardt C. The Gut Microbiota in Cardiovascular Disease and Arterial Thrombosis. Microorganisms 2019;7(12). 

• Panova-Noeva M, van der Meijden PEJ, Ten Cate H. Clinical Applications, Pitfalls, and Uncertainties of Thrombin Generation in the Presence of Platelets. J Clin Med 2019;9(1).

• Barco S. What's the Matter with Distal Deep Vein Thrombosis? Thromb Haemost 2019;19(10):1547-1549.

• Klok FA, Barco S. Optimal management of hormonal contraceptives after an episode of venous thromboembolism. Thromb Res 2019;181 Suppl 1:S1-S5.

• Lämmle B. Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy: Pathophysiology and Differentiation from Graft versus Host Disease. Thromb Haemost 2019;119(9):1382. 

• Bayer F, Ascher S, Pontarollo G, Reinhardt C. Antibiotic Treatment Protocols and Germ-Free Mouse Models in Vascular Research. Front Immunol 2019;10:2174.

• Keller K, Lankeit M. Current treatment of acute pulmonary embolism. PNEUMOLOGE. 2019; 16(5): 279-288. 

• Hobohm L, Lankeit M. [Pulmonary Embolism]. Dtsch Med Wochenschr 2019;144(18):1286-1300.

• Konstantinides SV, Meyer G. The 2019 ESC Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism. Eur Heart J 2019;40(42):3453-3455.

• Daiber A, Kröller-Schön S, Frenis K, Oelze M, Kalinovic S, Vujacic-Mirski K, Kuntic M, Bayo Jimenez MT, Helmstädter J, Steven S, Korac B, Münzel T. Environmental noise induces the release of stress hormones and inflammatory signaling molecules leading to oxidative stress and vascular dysfunction-Signatures of the internal exposome. Biofactors 2019;45(4):495-506

• Lackner KJ, Müller-Calleja N. Pathogenesis of antiphospholipid syndrome: recent insights and emerging concepts. Expert Rev Clin Immunol 2019;15(2):199-209.

• Daiber A, Xia N, Steven S, Oelze M, Hanf A, Kröller-Schön S, Münzel T, Li H. New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease. Int J Mol Sci 2019;20(1).

• Steven S, Frenis K, Oelze M, Kalinovic S, Kuntic M, Bayo Jimenez MT, Vujacic-Mirski K, Helmstadter J, Kröller-Schön S, Münzel T, Daiber A. Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease. Oxid Med Cell Longev 2019;2019:7092151.

• Lackner KJ, Müller-Calleja N. Cofactor-Independent Antiphospholipid Antibodies: Implications for Pathogenesis, Diagnosis, and Treatment of Antiphospholipid Syndrome. Hamostaseologie 2019;39(2):188-194.

• Karbach S, Lagrange J, Wenzel P. Thromboinflammation and Vascular Dysfunction. Hamostaseologie 2019;39(2):180-187.

• Reinhardt C. The Gut Microbiota as an Influencing Factor of Arterial Thrombosis. Hamostaseologie 2019;39(2):173-179.

• Madhusudhan T, Ruf W. Coagulation Signalling and Metabolic Disorders: Lessons Learned from Animal Models. Hamostaseologie 2019;39(2):164-172.

• Panova-Noeva M, Eggebrecht L, Prochaska JH, Wild PS. Potential of Multidimensional, Large-scale Biodatabases to Elucidate Coagulation and Platelet Pathways as an Approach towards Precision Medicine in Thrombotic Disease. Hamostaseologie 2019;39(2):152-163.

• Jurk K, Walter U. New Insights into Platelet Signalling Pathways by Functional and Proteomic Approaches. Hamostaseologie 2019;39(2):140-151. 

• Bochenek ML, Schäfer K. Role of Endothelial Cells in Acute and Chronic Thrombosis. Hamostaseologie 2019;39(2):128-139.

• Barco S, Konstantinides SV. Optimizing the Personalized, Risk-Adjusted Management of Pulmonary Embolism: An Integrated Clinical Trial Programme. Hamostaseologie 2019;39(2):117-127. 

• Johannes Wild, Philip Wenzel. „Myocardial injury“ und Myokardinfarkt – Konsequenzen für die Klinik im Kontext aktueller Leitlinien. Aktuel Kardiol 2019; 8(03): 193-198.

• Klok FA, Barco S, Siegerink B. Measuring functional limitations after venous thromboembolism: A call to action. Thromb Res 2019;178:59-62.

• Wenzel P. Monocytes as immune targets in arterial hypertension. Br J Pharmacol 2019;176(12):1966-1977.

• Keller K, Hobohm L, Münzel T, Ostad MA. Incidence of infective endocarditis before and after the guideline modification regarding a more restrictive use of prophylactic antibiotics therapy in the USA and Europe. Minerva Cardioangiol 2019;67(3):200-206.

• Formes H, Reinhardt C. The gut microbiota - a modulator of endothelial cell function and a contributing environmental factor to arterial thrombosis. Expert Rev Hematol 2019:1-9.

• Keller K. Sarcopenia. Wien Med Wochenschr 2019;169(7-8):157-172.

• Gogiraju R, Bochenek ML, Schäfer K. Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure. Front Cardiovasc Med 2019;6:20.

• Petris AO, Konstantinides S, Tint D, Cimpoesu D, Pop C. Therapeutic Advances in Emergency Cardiology: Acute Pulmonary Embolism. Am J Ther 2019;26(2):e248-e256.

• Aissaoui N, Konstantinides S, Meyer G. What's new in severe pulmonary embolism? Intensive Care Med 2019;45(1):75-77.

Editorials und Fachbeiträge 2019

• Valerio L, Trinchero A, Barco S. Telemedicine and decentralized models of care: from anticoagulant monitoring to an expanded concept of vascular medicine. Intern Emerg Med 2019;14(8):1213-1215.

• Bauersachs R, Langer F, Kalka C, Konstantinides S, Klamroth R, Oldenburg J, Schellong S, Scholz U, Stucker M, Lindhoff-Last E. Treatment of the antiphospholipid syndrome with direct oral anticoagulantsPosition statement of German societies. Vasa 2019;48(6):483-486.

• Barco S, Konstantinides SV, Lankeit M. Response to 'Detecting right ventricular dysfunction in patients diagnosed with low-risk pulmonary embolism: is routine computed tomographic pulmonary angiography sufficient?'. Eur Heart J 2019;40(40):3357-3358.

• Linde C, Members of the ESC Membership Committee the ESC Officers Sophie Squarta, Director Membership Community. The Membership Committee of the ESC. Cardiovasc Res 2019;115(12):e130-e132.

• Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ainle FN, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL, The Task Force for the diagnosis management of acute pulmonary embolism of the European Society of Cardiology. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J 2019;54(3).

• Rosenkranz S, Diller GP, Dumitrescu D, Ewert R, Ghofrani HA, Grünig E, Halank M, Held M, Kaemmerer H, Klose H, Kovacs G, Konstantinides S, Lang IM, Lange TJ, Leuchte H, Mayer E, Olschewski A, Olschewski H, Olsson KM, Opitz C, Schermuly RT, Seeger W, Wilkens H, Hoeper MM. [Hemodynamic Definition of Pulmonary Hypertension: Commentary on the Proposed Change by the 6th World Symposium on Pulmonary Hypertension]. Dtsch Med Wochenschr 2019;144(19):1367-1372.

• Reinhardt C. The Microbiota: A Microbial Ecosystem Built on Mutualism Prevails. J Innate Immun 2019;11(5):391-392.

• Ruf W. Translational Research in Thrombosis and Haemostasis. Hamostaseologie 2019;39(2):115-116.

• Konstantinides SV, Münzel T, Ruf W. Center for Thrombosis and Hemostasis Mainz. Eur Heart J 2019;40(23):1827-1829.

• Keller K, Hobohm L. Identification of normotensive patients with pulmonary embolism who may benefit from thrombolysis. Int J Cardiol 2019;281:125-126.

• Prochaska JH, Tröbs SO, Wild PS. PCSK9: A link between air pollution and cardiovascular disease? Eur J Prev Cardiol 2019;26(6):576-577.

• Pontarollo G, Melzow F, Reinhardt C. Comment on "Endothelial Protein C Receptor (EPCR), Protease Activated Receptor-1 (PAR-1) and Their Interplay in Cancer Growth and Metastatic Dissemination" Cancers 2019, 11, 51. Cancers (Basel) 2019;11(3).

• Becker C, Reinhardt C. Unexpected role of natural killer cell-derived interferon-gamma as a driver of NETosis and DVT. J Thromb Haemost 2019;17(2):400-402.

Originalartikel 2018

• Mahmoudpour SH, Asselbergs FW, Souverein PC, de Boer A, Maitland-van der Zee AH. Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study. Br J Clin Pharmacol 2018;84(10):2365-2372.

• Mahmoudpour SH, Bandapalli OR, da Silva Filho MI, Campo C, Hemminki K, Goldschmidt H, Merz M, Försti A. Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients. BMC Cancer 2018;18(1):820.

• Keller K, Beule J, Balzer JO, Dippold W. D-Dimer and thrombus burden in acute pulmonary embolism. Am J Emerg Med 2018;36(9):1613-1618.
• Steven S, Oelze M, Hausding M, Roohani S, Kashani F, Kröller-Schön S, Helmstädter J, Jansen T, Baum C, Iglarz M, Schulz E, Münzel T, Daiber A. The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation. Oxid Med Cell Longev 2018;2018:7845629.
• Barco S, Ende-Verhaar YM, Becattini C, Jimenez D, Lankeit M, Huisman MV, Konstantinides SV, Klok FA. Differential impact of syncope on the prognosis of patients with acute pulmonary embolism: a systematic review and meta-analysis. Eur Heart J 2018.
• Wilkens H, Konstantinides S, Lang IM, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohe C, Guth S, Held M, Hinrichs JB, Hoeper MM, Klepetko W, Kramm T, Kruger U, Lankeit M, Meyer BC, Olsson KM, Schafers HJ, Schmidt M, Seyfarth HJ, Ulrich S, Wiedenroth CB, Mayer E. Chronic thromboembolic pulmonary hypertension (CTEPH): Updated Recommendations from the Cologne Consensus Conference 2018. Int J Cardiol 2018;272S:69-78.
• Ogorodnikov A, Levin M, Tattikota S, Tokalov S, Hoque M, Scherzinger D, Marini F, Poetsch A, Binder H, Macher-Göppinger S, Probst HC, Tian B, Schaefer M, Lackner KJ, Westermann F, Danckwardt S. Transcriptome 3'end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma. Nat Commun 2018;9(1):5331.
• Dentali F, Barco S, Pegoraro S, Di Minno MND, Mastroiacovo D, Pomero F, Lodigiani C, Bagna F, Sartori M, Barillari G, Mumoli N, Napolitano M, Passamonti SM, Benedetti R, Ageno W, Di Nisio M. Residual vein obstruction in patients diagnosed with acute isolated distal deep vein thrombosis associated with active cancer. J Thromb Thrombolysis 2018;46(3):404-408.
• Scheres LJJ, Lijfering WM, Middeldorp S, Cheung YW, Barco S, Cannegieter SC, Coppens M. Measurement of coagulation factors during rivaroxaban and apixaban treatment: Results from two crossover trials. Res Pract Thromb Haemost 2018;2(4):689-695.
• Keller K, Beule J, Balzer JO, Dippold W. Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of Pulmonary Embolism) Study Programme. Acta Medica (Hradec Kralove) 2018;61(3):93-97.
• Keller K, Hobohm L, Engelhardt M. Impact of Atrial Fibrillation on Postoperative Adverse Outcomes of Surgical Patients With Knee Endoprosthetic Surgery. J Arthroplasty 2018;33(11):3567-3573.
• Keller K, Hobohm L, Münzel T, Ostad MA, Espinola-Klein C. Syncope in haemodynamically stable and unstable patients with acute pulmonary embolism - Results of the German nationwide inpatient sample. Sci Rep 2018;8(1):15789.
• Klok FA, Barco S, Turpie AGG, Haas S, Kreutz R, Mantovani LG, Gebel M, Herpers M, Bugge JP, Kostantinides SV, Ageno W. Predictive value of venous thromboembolism (VTE)-BLEED to predict major bleeding and other adverse events in a practice-based cohort of patients with VTE: results of the XALIA study. Br J Haematol 2018;183(3):457-465.
• Ligthart S, Vaez A, Vosa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM […] Wild PS […] Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. Am J Hum Genet 2018;103(5):691-706.
• Eggebrecht L, Prochaska JH, Schulz A, Arnold N, Jünger C, Gobel S, Laubert-Reh D, Binder H, Beutel ME, Pfeiffer N, Blankenberg S, Lackner KJ, Spronk HM, Ten Cate H, Münzel T, Wild PS. Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study. J Am Heart Assoc 2018;7(17):e008650.
• Göbel S*, Prochaska JH*, Eggebrecht L, Schmitz R, Jünger C, Lamparter H, Nagler M, Keller K, Coldewey M, Tröbs SO, Diestelmeier S, Schwuchow-Thonke S, Bickel C, Lauterbach M, Lackner KJ, Cate HT, Münzel T, Hardt R, Wild PS. Management of Oral Anti-Coagulation in Patients with Heart Failure-Insights from the ThrombEVAL Study. Thromb Haemost 2018;118(11):1930-1939. * equal contribution
• Haase T, Müller C, Krause J, Rothemeier C, Stenzig J, Kunze S, Waldenberger M, Münzel T, Pfeiffer N, Wild PS, Michal M, Marini F, Karakas M, Lackner KJ, Blankenberg S, Zeller T. Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking. Biomolecules 2018;8(3).
• Niekamp C, Atzler D, Ojeda FM, Sinning CR, Lackner KJ, Boger RH, Münzel T, Beutel ME, Schmidtmann I, Pfeiffer N, Leuschner A, Blankenberg S, Wild PS, Zeller T, Schwedhelm E, Schnabel RB. Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study. Biomolecules 2018;8(3).
• Tibubos AN, Beutel ME, Schulz A, Klein EM, Brahler E, Michal M, Münzel T, Wild PS, Lackner K, Konig J, Pfeiffer N, Wiltink J. Is assessment of depression equivalent for migrants of different cultural backgrounds? Results from the German population-based Gutenberg Health Study (GHS). Depress Anxiety 2018;35(12):1178-1189.
• van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS, Gibson Q, Gudbjartsson DF […] Wild PS […] Stefansson K, Stricker BH, van der Harst P, van Duijn CM, Wilson JF, Gharib SA, de Bakker PIW, Isaacs A, Arking DE, Sotoodehnia N. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nat Commun 2018;9(1):2904.
• Höhn R, Nickels S, Schuster AK, Wild PS, Münzel T, Lackner KJ, Schmidtmann I, Beutel M, Pfeiffer N. Prevalence of glaucoma in Germany: results from the Gutenberg Health Study. Graefes Arch Clin Exp Ophthalmol 2018;256(9):1695-1702.
• Magnussen C, Ojeda FM, Wild PS, Sorensen N, Rostock T, Hoffmann BA, Prochaska J, Lackner KJ, Beutel ME, Blettner M, Pfeiffer N, Rzayeva N, Sinning CR, Blankenberg S, Münzel T, Zeller T, Schnabel RB. Atrial Fibrillation Manifestations Risk Factors and Sex Differences in a Population-Based Cohort (From the Gutenberg Health Study). Am J Cardiol 2018;122(1):76-82.
• Prochaska JH, Göbel S, Nagler M, Knöpfler T, Eggebrecht L, Lamparter H, Panova-Noeva M, Keller K, Coldewey M, Bickel C, Lauterbach M, Hardt R, Espinola-Klein C, Ten Cate H, Rostock T, Münzel T, Wild PS. Sustained atrial fibrillation increases the risk of anticoagulation-related bleeding in heart failure. Clin Res Cardiol 2018.
• Nourse J, Braun J, Lackner K, Hüttelmaier S, Danckwardt S. Large-scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system. J Thromb Haemost 2018;16(11):2233-2245.
• Colucci G, Helsing K, Biasiutti FD, Raio L, Schmid P, Tsakiris DA, Eberle B, Surbek D, Lämmle B, Alberio L. Standardized Management Protocol in Severe Postpartum Hemorrhage: A Single-Center Study. Clin Appl Thromb Hemost 2018;24(6):884-893.
• Klatt C, Krüger I, Zey S, Krott KJ, Spelleken M, Gowert NS, Oberhuber A, Pfaff L, Luckstadt W, Jurk K, Schaller M, Al-Hasani H, Schrader J, Massberg S, Stark K, Schelzig H, Kelm M, Elvers M. Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis. J Clin Invest 2018;128(9):3906-3925.
• Urbahn MA, Kaup SC, Reusswig F, Kruger I, Spelleken M, Jurk K, Klier M, Lang PA, Elvers M. Phospholipase D1 regulation of TNF-alpha protects against responses to LPS. Sci Rep 2018;8(1):10006.
• Falter T, Herold S, Weyer-Elberich V, Scheiner C, Schmitt V, von Auer C, Messmer X, Wild P, Lackner KJ, Lämmle B, Scharrer I. Relapse Rate in Survivors of Acute Autoimmune Thrombotic Thrombocytopenic Purpura Treated with or without Rituximab. Thromb Haemost 2018;118(10):1743-1751.
• Brandt M, Giokoglu E, Garlapati V, Bochenek ML, Molitor M, Hobohm L, Schönfelder T, Münzel T, Kossmann S, Karbach SH, Schäfer K, Wenzel P. Pulmonary Arterial Hypertension and Endothelial Dysfunction Is Linked to NADPH Oxidase-Derived Superoxide Formation in Venous Thrombosis and Pulmonary Embolism in Mice. Oxid Med Cell Longev 2018;2018:1860513.
  Jansen T, Kröller-Schön S, Schönfelder T, Foretz M, Viollet B, Daiber A, Oelze M, Brandt M, Steven S, Kvandova M, Kalinovic S, Lagrange J, Keaney JF, Jr., Münzel T, Wenzel P, Schulz E. alpha1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction. Cardiovasc Res 2018;114(14):1883-1893.
• Kröller-Schön S, Daiber A, Steven S, Oelze M, Frenis K, Kalinovic S, Heimann A, Schmidt FP, Pinto A, Kvandova M, Vujacic-Mirski K, Filippou K, Dudek M, Bosmann M, Klein M, Bopp T, Hahad O, Wild PS, Frauenknecht K, Methner A, Schmidt ER, Rapp S, Mollnau H, Münzel T. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation. Eur Heart J 2018;39(38):3528-3539.
• Sotiriou E, Heiner S, Jansen T, Brandt M, Schmidt KH, Kreitner KF, Emrich T, Schultheiss HP, Schulz E, Münzel T, Wenzel P. Therapeutic implications of a combined diagnostic workup including endomyocardial biopsy in an all-comer population of patients with heart failure: a retrospective analysis. ESC Heart Fail 2018;5(4):630-641.
• Lindskog Jonsson A, Caesar R, Akrami R, Reinhardt C, Fak Hallenius F, Boren J, Bäckhed F. Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe(-/-) Mice. Arterioscler Thromb Vasc Biol 2018;38(10):2318-2326.
• Klok FA, Barco S, Konstantinides SV, Dartevelle P, Fadel E, Jenkins D, Kim NH, Madani M, Matsubara H, Mayer E, Pepke-Zaba J, Delcroix M, Lang IM. Determinants of diagnostic delay in chronic thromboembolic pulmonary hypertension: results from the European CTEPH Registry. Eur Respir J 2018;52(6).
• Kaymaz C, Akbal OY, Hakgor A, Tokgoz HC, Karagoz A, Tanboga IH, Tanyeri S, Keskin B, Turkday S, Demir D, Dogan C, Bayram Z, Acar RD, Guvendi B, Ozdemir N, Tapson VF, Konstantinides S. A five-year, single-centre experience on ultrasound-assisted, catheter-directed thrombolysis in patients with pulmonary embolism at high risk and intermediate to high risk. EuroIntervention 2018;14(10):1136-1143.
• Spyropoulos AC, Ageno W, Albers GW, Elliott CG, Halperin JL, Hiatt WR, Maynard GA, Steg PG, Weitz JI, Suh E, Spiro TE, Barnathan ES, Raskob GE, Investigators M. Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness. N Engl J Med 2018;379(12):1118-1127.
• Trinchero A, Scheres LJJ, Prochaska JH, Ambaglio C, Wild PS, Middeldorp S, Konstantinides SV, Barco S. Sex-specific differences in the distal versus proximal presenting location of acute deep vein thrombosis. Thromb Res 2018;172:74-79.
• Dellas C, Lobo JL, Rivas A, Ballaz A, Portillo AK, Nieto R, Del Rey JM, Zamorano JL, Lankeit M*, Jimenez D*. Risk stratification of acute pulmonary embolism based on clinical parameters, H-FABP and multidetector CT. Int J Cardiol 2018;265:223-228. *equal contribution.
• Khandagale A, Kittner JM, Mann A, Ascher S, Kollar B, Reinhardt C. Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis. Biol Open 2018;7(7).
• Westmeier D, Solouk-Saran D, Vallet C, Siemer S, Docter D, Götz H, Männ L, Hasenberg A, Hahlbrock A, Erler K, Reinhardt C, Schilling O, Becker S, Gunzer M, Hasenberg M, Knauer SK, Stauber RH. Nanoparticle decoration impacts airborne fungal pathobiology. Proc Natl Acad Sci U S A 2018;115(27):7087-7092.
• Dellas C, Lobo JL, Rivas A, Ballaz A, Portillo AK, Nieto R, Del Rey JM, Zamorano JL, Lankeit M, Jimenez D. Risk stratification of acute pulmonary embolism based on clinical parameters, H-FABP and multidetector CT. Int J Cardiol 2018;265:223-228.
• Unterrainer JM, Domschke K, Rahm B, Wiltink J, Schulz A, Pfeiffer N, Lackner KJ, Münzel T, Wild PS, Beutel M. Subclinical levels of anxiety but not depression are associated with planning performance in a large population-based sample. Psychol Med 2018;48(1):168-174.
• Rezapour J, Nickels S, Schuster AK, Michal M, Münzel T, Wild PS, Schmidtmann I, Lackner K, Schulz A, Pfeiffer N, Beutel ME. Prevalence of depression and anxiety among participants with glaucoma in a population-based cohort study: The Gutenberg Health Study. BMC Ophthalmol 2018;18(1):157.
• Müller-Calleja N, Ritter S, Hollerbach A, Falter T, Lackner KJ, Ruf W. Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies. Blood Adv 2018;2(9):979-986.
• Rue-Albrecht K, Marini F, Soneson C, Lun ATL. iSEE: Interactive SummarizedExperiment Explorer. F1000Res 2018;7:741.
• Lamparter J, Schmidtmann I, Schuster AK, Siouli A, Wasielica-Poslednik J, Mirshahi A, Höhn R, Unterrainer J, Wild PS, Binder H, Lackner K, Beutel ME, Münzel T, Pfeiffer N, Hoffmann EM. Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness. PLoS One 2018;13(5):e0197682.
• Wiltink J, Michal M, Jünger C, Münzel T, Wild PS, Lackner KJ, Blettner M, Pfeiffer N, Brähler E, Beutel ME. Associations between degree and sub-dimensions of depression and metabolic syndrome (MetS) in the community: results from the Gutenberg Health Study (GHS). BMC Psychiatry 2018;18(1):114.
• Parry BA, Chang AM, Schellong SM, House SL, Fermann GJ, Deadmon EK, Giordano NJ, Chang Y, Cohen J, Robak N, Singer AJ, Mulrow M, Reibling ET, Francis S, Griffin SM, Prochaska JH, Davis B, McNelis P, Delgado J, Kumpers P, Werner N, Gentile NT, Zeserson E, Wild PS, Limkakeng AT, Jr., Walters EL, LoVecchio F, Theodoro D, Hollander JE, Kabrhel C. International, multicenter evaluation of a new D-dimer assay for the exclusion of venous thromboembolism using standard and age-adjusted cut-offs. Thromb Res 2018;166:63-70.
• Panova-Noeva M, Schulz A, Spronk HM, Beicht A, Laubert-Reh D, van Oerle R, Arnold N, Prochaska JH, Blettner M, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study. Thromb Haemost 2018;118(5):873-882.
• Yu Y, Boing AN, Hau CM, Hajji N, Ruf W, Sturk A, Nieuwland R. Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment. Thromb Haemost 2018;118(6):990-1000.
• Bochenek ML, Bauer T, Gogiraju R, Nadir Y, Mann A, Schönfelder T, Hunig L, Brenner B, Münzel T, Wenzel P, Konstantinides S, Schäfer K. The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice. Blood Adv 2018;2(11):1300-1314.
• Hellenkamp K, Pruszczyk P, Jimenez D, Wyzgal A, Barrios D, Ciurzynski M, Morillo R, Hobohm L, Keller K, Kurnicka K, Kostrubiec M, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study. Eur Respir J 2018;51(4).
• Faber J, Wingerter A, Neu MA, Henninger N, Eckerle S, Münzel T, Lackner KJ, Beutel ME, Blettner M, Rathmann W, Peters A, Meisinger C, Linkohr B, Neuhauser H, Kaatsch P, Spix C, Schneider A, Merzenich H, Panova-Noeva M, Prochaska JH, Wild PS. Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors: data from the German CVSS-study. Eur Heart J 2018;39(17):1555-1562.
• Herrmann WJ, Weikert C, Bergmann M, Boeing H, Katzke VA, Kaaks R, Tiller D, Greiser KH, Heier M, Meisinger C, Schmidt CO, Neuhauser H, Heidemann C, Jünger C, Wild PS, Schramm SH, Jöckel KH, Dörr M, Pischon T. [Assessing incident cardiovascular and metabolic diseases in epidemiological cohort studies in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2018;61(4):420-431.
• Lauber S, Limacher A, Tritschler T, Stalder O, Mean M, Righini M, Aschwanden M, Beer JH, Frauchiger B, Osterwalder J, Kucher N, Lämmle B, Cornuz J, Angelillo-Scherrer A, Matter CM, Husmann M, Banyai M, Staub D, Mazzolai L, Hugli O, Rodondi N, Aujesky D. Predictors and Outcomes of Recurrent Venous Thromboembolism in Elderly Patients. Am J Med 2018;131(6):703 e707-703 e716.
• Makhoul S, Walter E, Pagel O, Walter U, Sickmann A, Gambaryan S, Smolenski A, Zahedi RP, Jurk K. Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets. Nitric Oxide 2018;76:71-80.
• Ebert J, Wilgenbus P, Teiber JF, Jurk K, Schwierczek K, Döhrmann M, Xia N, Li H, Spiecker L, Ruf W, Horke S. Paraoxonase-2 regulates coagulation activation through endothelial tissue factor. Blood 2018;131(19):2161-2172.
• Panova-Noeva M, Schulz A, Arnold N, Hermanns MI, Prochaska JH, Laubert-Reh D, Spronk HM, Blettner M, Beutel M, Pfeiffer N, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Coagulation and inflammation in long-term cancer survivors: results from the adult population. J Thromb Haemost 2018;16(4):699-708.
• Kurakula K, Koenis DS, Herzik MA, Jr., Liu Y, Craft JW, Jr., van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Sen M. Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica 2018;103(6):1073-1082.
• Eggebrecht L*, Prochaska JH*, Schleuter L, Nagler M, Hardt R, Schinzel H, Münzel T, Wild PS. [Physicians' Opinion on Health Care in Oral Anticoagulation]. Dtsch Med Wochenschr 2018;143(9):e76-e84.
• Siegismund CS, Escher F, Lassner D, Kühl U, Gross U, Fruhwald F, Wenzel P, Münzel T, Frey N, Linke RP, Schultheiss HP. Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis. Eur J Heart Fail 2018;20(4):751-757.
• Jimenez-Alcazar M, Limacher A, Panda R, Mean M, Bitterling J, Peine S, Renne T, Beer JH, Aujesky D, Lämmle B, Fuchs TA. Circulating extracellular DNA is an independent predictor of mortality in elderly patients with venous thromboembolism. PLoS One 2018;13(2):e0191150.
• Rothmeier AS, Liu E, Chakrabarty S, Disse J, Mueller BM, Ostergaard H, Ruf W. Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling. Blood 2018;131(6):674-685.
• Rodger M, Langlois N, Middeldorp S, Kahn S, Sandset PM, Brighton T, Huisman MV, Meyer G, Konstantinides S, Ageno W, Morange P, Garcia D, Kreuziger LB, Young L, Key N, Monreal M, Jimenez D. Initial strides for invent-VTE: Towards global collaboration to accelerate clinical research in venous thromboembolism. Thromb Res 2018;163:128-131.
• Schönfelder T, Brandt M, Kossmann S, Knopp T, Münzel T, Walter U, Karbach SH, Wenzel P. Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis. Sci Rep 2018;8(1):3013.
• Lagrange J, Kossmann S, Kiouptsi K, Wenzel P. Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls. J Vis Exp 2018(131).
• Barco S, Vicaut E, Klok FA, Lankeit M, Meyer G, Konstantinides SV, Investigators P. Improved identification of thrombolysis candidates amongst intermediate-risk pulmonary embolism patients: implications for future trials. Eur Respir J 2018;51(1).
• Oelze M, Welschof P, Knorr M, Tran LP, Ullmann E, Stamm P, Kröller-Schön S, Jansen T, Kopp M, Schulz E, Gori T, Burgin K, Scherhag A, Sartor D, Münzel T, Daiber A. Basic in vitro Characterization of the Vasodilatory Potential of 2-Aminoethyl Nitrate Fixed-Dose Combinations with Cilostazol, Metoprolol and Valsartan. Pharmacology 2018;101(1-2):54-63.
• Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kröller-Schön S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Münzel T, Daiber A. CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice. Cardiovasc Res 2018;114(2):312-323.
• Keller K, Münzel T, Ostad MA. Sex-specific differences in mortality and the obesity paradox of patients with myocardial infarction ages >70 y. Nutrition 2018;46:124-130.
• Wang X, Hausding M, Weng SY, Kim YO, Steven S, Klein T, Daiber A, Schuppan D. Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis. Antioxid Redox Signal 2018;28(2):87-109.

Reviews 2018

• Graf C, Ruf W. Tissue factor as a mediator of coagulation and signaling in cancer and chronic inflammation. Thromb Res 2018;164 Suppl 1:S143-S147
• Saffarzadeh M. Neutrophil Extracellular Traps as a Drug Target to Counteract Chronic and Acute Inflammation. Curr Pharm Biotechnol 2018;19(15):1196-1202.
• Reinhardt C. The Involvement of Toll-like Receptor-2 in Arterial Thrombus Formation. Hamostaseologie 2018;38(4):223-228.
• Carnevale D, Wenzel P. Mechanical stretch on endothelial cells interconnects innate and adaptive immune response in hypertension. Cardiovasc Res 2018;114(11):1432-1434.
• Kiouptsi K, Reinhardt C. Contribution of the commensal microbiota to atherosclerosis and arterial thrombosis. Br J Pharmacol 2018;175(24):4439-4449.
• Subramaniam S, Kanse SM, Kothari H, Reinhardt C, Fletcher C. Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood Coagul Fibrinolysis 2018;29(8):668-682.
• Westmeier D, Hahlbrock A, Reinhardt C, Fröhlich-Nowoisky J, Wessler S, Vallet C, Pöschl U, Knauer SK, Stauber RH. Nanomaterial-microbe cross-talk: physicochemical principles and (patho)biological consequences. Chem Soc Rev 2018;47(14):5312-5337.
• Barco S, Konstantinides SV. Pulmonary Embolism: Contemporary Medical Management and Future Perspectives. Ann Vasc Dis 2018;11(3):265-276.
• Nguyen TS, Lapidot T, Ruf W. Extravascular coagulation in hematopoietic stem and progenitor cell regulation. Blood 2018;132(2):123-131.
• Ruf W. ISTH 2017 Berlin revisited. Res Pract Thromb Haemost 2018;2(1):17-18.
• Zelaya H, Rothmeier AS, Ruf W. Tissue factor at the crossroad of coagulation and cell signaling. J Thromb Haemost 2018;16(10):1941-1952.
• Kiouptsi K, Ruf W, Reinhardt C. Microbiota-Derived Trimethylamine. Circ Res 2018;123(10):1112-1114.
• Prochaska JH, Wild PS. Traffic-associated air pollution as a risk factor for cancer in individuals with coronary artery disease. Eur J Prev Cardiol 2018:2047487318768942.
• Ruf W. Proteases, Protease-Activated Receptors, and Atherosclerosis. Arterioscler Thromb Vasc Biol 2018;38(6):1252-1254.
• Konstantinides SV. Diagnosis of Cerebral Venous Thrombosis: The Complementary Value of Imaging Methods. Thromb Haemost 2018;118(6):956.
• Huisman MV, Barco S, Cannegieter SC, Le Gal G, Konstantinides SV, Reitsma PH, Rodger M, Vonk Noordegraaf A, Klok FA. Pulmonary embolism. Nat Rev Dis Primers 2018;4:18028.
• Konstantinides SV. Detection and treatment of chronic thromboembolic pulmonary hypertension: Still a lot of homework to do. Hellenic J Cardiol 2018;59(1):24-25.
• Klok FA, Barco S, Konstantinides SV. Evaluation of VTE-BLEED for predicting intracranial or fatal bleeding in stable anticoagulated patients with venous thromboembolism. Eur Respir J 2018;51(4).
• Prochaska JH, Arnold N, Jünger C, Münzel T, Wild PS. [Prevention of cardiovascular diseases]. Herz 2018;43(1):87-100.
• Ascher S, Reinhardt C. The gut microbiota: An emerging risk factor for cardiovascular and cerebrovascular disease. Eur J Immunol 2018;48(4):564-575.
• Konstantinides SV, Barco S. Prevention of early complications and late consequences after acute pulmonary embolism: Focus on reperfusion techniques. Thromb Res 2018;164:163-169.
• Klok FA, Barco S. Follow-up after acute Pulmonary Embolism. Hamostaseologie 2018;38(1):22-32.
• Münzel T, Daiber A. Inorganic nitrite and nitrate in cardiovascular therapy: A better alternative to organic nitrates as nitric oxide donors? Vascul Pharmacol 2018;102:1-10.
• Münzel T, Daiber A. The potential of aldehyde dehydrogenase 2 as a therapeutic target in cardiovascular disease. Expert Opin Ther Targets 2018;22(3):217-231.
• Spronk HMH, Padro T, Siland JE, Prochaska JH, Winters J, van der Wal AC, Posthuma JJ, Lowe G, d'Alessandro E, Wenzel P, Coenen DM, Reitsma PH, Ruf W, van Gorp RH, Koenen RR, Vajen T, Alshaikh NA, Wolberg AS, Macrae FL, Asquith N, Heemskerk J, Heinzmann A, Moorlag M, Mackman N, van der Meijden P, Meijers JCM, Heestermans M, Renne T, Dolleman S, Chayoua W, Ariens RAS, Baaten CC, Nagy M, Kuliopulos A, Posma JJ, Harrison P, Vries MJ, Crijns H, Dudink E, Buller HR, Henskens YMC, Sjalander A, Zwaveling S, Erkuner O, Eikelboom JW, Gulpen A, Peeters F, Douxfils J, Olie RH, Baglin T, Leader A, Schotten U, Scaf B, van Beusekom HMM, Mosnier LO, van der Vorm L, Declerck P, Visser M, Dippel DWJ, Strijbis VJ, Pertiwi K, Ten Cate-Hoek AJ, Ten Cate H. Atherothrombosis and Thromboembolism: Position Paper from the Second Maastricht Consensus Conference on Thrombosis. Thromb Haemost 2018;118(2):229-250.
• Barco S, Konstantinides S, Huisman MV, Klok FA. Diagnosis of recurrent venous thromboembolism. Thromb Res 2018;163:229-235.
• Subramaniam S, Scharrer I. Procoagulant activity during viral infections. Front Biosci (Landmark Ed) 2018;23:1060-1081.
• Khandagale A, Reinhardt C. Gut microbiota - architects of small intestinal capillaries. Front Biosci (Landmark Ed) 2018;23:752-766.

Editorials und Fachbeiträge 2018

• Konstantinides SV. Introduction to the Special Issue: 'Update on Pulmonary Embolism'. Hamostaseologie 2018;38(2):71-72.
• Kossmann S, Wenzel P. Under Pressure: A New Role for CD11c(+) Myeloid Cells in Hypertension. Hypertension 2018;71(4):557-558.
• Brandt M, Wenzel P. Alcohol puts the heart under pressure: Acetaldehyde activates a localized renin angiotensin aldosterone system within the myocardium in alcoholic cardiomyopathy. Int J Cardiol 2018;257:220-221.

Originalartikel 2017

• Wilton P, Steidel M, Krczal G, Hermanns I, Pfützner A, Konnerth A, Boonrod K. Identification of Highly Specific scFvs against Total Adiponectin for Diagnostic Purposes. Biology (Basel) 2017;6(2).
• Wild J, Gori T, Münzel T, Wenzel P. Successful percutaneous coronary intervention for an in-stent chronic total occlusion in a patient with dextrocardia: a case report. BMC Cardiovasc Disord 2017;17(1):281.
• Lagrange J, Didelot M, Mohamadi A, Walton LA, Bloemen S, de Laat B, Louis H, Thornton SN, Derby B, Sherratt MJ, Feve B, Challande P, Akhtar R, Cruickshank JK, Lacolley P, Regnault V. Implication of Free Fatty Acids in Thrombin Generation and Fibrinolysis in Vascular Inflammation in Zucker Rats and Evolution with Aging. Front Physiol 2017;8:949.
• Klok FA, Ageno W, Barco S, Binder H, Brenner B, Duerschmied D, Empen K, Faggiano P, Ficker JH, Galiè N, Ghuysen A, Held M, Heydenreich N, Huisman MV, Jiménez D, Kozak M, Lang IM, Lankeit M, Münzel T, Petris A, Pruszczyk P, Quitzau K, Schellong S, Schmidt KH, Stefanovic BS, Verschuren F, Wolf-Puetz A, Meyer G, Konstantinides SV, Investigators P-. Dabigatran after Short Heparin Anticoagulation for Acute Intermediate-Risk Pulmonary Embolism: Rationale and Design of the Single-Arm PEITHO-2 Study. Thromb Haemost 2017;117(12):2425-2434.
• Stetzenbach M, Schnorbus B, Sagoschen I, Bleser W, Legner D, Stürer A. [Acute Monkshood Intoxication Requiring Acute Resuscitation in Suicidal Intent]. Anasthesiol Intensivmed Notfallmed Schmerzther 2017;52(9):641-644.
• Seiler E, Limacher A, Mean M, Beer HJ, Osterwalder J, Frauchiger B, Righini M, Aschwanden M, Matter CM, Banyai M, Kucher N, Staub D, Lämmle B, Rodondi N, Squizzato A, Aujesky D. Derivation and validation of a novel bleeding risk score for elderly patients with venous thromboembolism on extended anticoagulation. Thromb Haemost 2017;117(10).
• Lankeit M, Krieg V, Hobohm L, Kölmel S, Liebetrau C, Konstantinides S, Hamm CW, Mayer E, Wiedenroth CB, Guth S. Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant 2017.
• Cheung YW, Barco S, Mathot RAA, van den Dool EJ, Stroobants AK, Serlie MJ, Middeldorp S, Coppens M. Pharmacokinetics of dabigatran etexilate and rivaroxaban in patients with short bowel syndrome requiring parenteral nutrition: The PDER PAN study. Thromb Res 2017;160:76-82.
• Barco S, Pomero F, Di Minno MND, Tamborini Permunian E, Malato A, Pasca S, Barillari G, Fenoglio L, Siragusa S, Di Minno G, Ageno W, Dentali F. Clinical course of patients with symptomatic isolated superficial vein thrombosis: the ICARO follow-up study. J Thromb Haemost 2017;15(11):2176-2183.
• Keller K, Beule J, Balzer JO, Dippold W. Renal function as a cofactor for risk stratification and short-term outcome in acute pulmonary embolism. Exp Gerontol 2017;100:11-16.
• Marquardt A, Al-Dabet MM, Ghosh S, Kohli S, Manoharan J, ElWakiel A, Gadi I, Bock F, Nazir S, Wang H, Lindquist JA, Nawroth PP, Madhusudhan T, Mertens PR, Shahzad K, Isermann B. Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy. J Am Soc Nephrol 2017;28(11):3182-3189.
• Schnorbus B, Wiebe J, Capodanno D, Brugaletta S, Geraci S, Mehilli J, Latib A, Lesiak M, Jensen C, Mattesini A, Münzel T, Capranzano P, Di Mario C, Naber C, Araszkiewicz A, Colombo A, Caramanno G, Sabate M, Tamburino C, Nef H, Gori T. Twelve-month outcomes after bioresorbable vascular scaffold implantation in patients with acute coronary syndromes. Data from the European Multicenter GHOST-EU Extended Registry. EuroIntervention 2017;13(9):e1104-e1111.
• Müller-Calleja N, Hollerbach A, Hauser F, Canisius A, Orning C, Lackner KJ. Antiphospholipid antibody-induced cellular responses depend on epitope specificity : implications for treatment of antiphospholipid syndrome. J Thromb Haemost 2017;15(12):2367-2376.
• Beutel ME, Brähler E, Wiltink J, Michal M, Klein EM, Jünger C, Wild PS, Münzel T, Blettner M, Lackner K, Nickels S, Tibubos AN. Emotional and tangible social support in a German population-based sample: Development and validation of the Brief Social Support Scale (BS6). PLoS One 2017;12(10):e0186516.
• Schuster AK, Pfeiffer N, Nickels S, Schulz A, Wild PS, Blettner M, Lackner K, Beutel ME, Münzel T, Vossmerbaeumer U. Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study. J Ophthalmol 2017;2017:2190347.
• Steven S, Dib M, Roohani S, Kashani F, Münzel T, Daiber A. Time Response of Oxidative/Nitrosative Stress and Inflammation in LPS-Induced Endotoxaemia-A Comparative Study of Mice and Rats. Int J Mol Sci 2017;18(10).
• Nielsen AL, Sorensen AB, Holmberg HL, Gandhi PS, Karlsson J, Buchardt J, Lamberth K, Kjelgaard-Hansen M, Ley CD, Sorensen BB, Ruf W, Olsen OH, Ostergaard H. Engineering of a membrane-triggered activity switch in coagulation factor VIIa. Proc Natl Acad Sci U S A 2017;114(47):12454-12459.
• Jagodzinski A, Neumann JT, Ojeda F, Sorensen NA, Wild P, Münzel T, Zeller T, Westermann D, Blankenberg S. Cardiovascular Biomarkers in Hypertensive Patients with Medical Treatment-Results from the Randomized TEAMSTA Protect I Trial. Clin Chem 2017;63(12):1877-1885.
• Gowert NS, Krüger I, Klier M, Donner L, Kipkeew F, Gliem M, Bradshaw NJ, Lutz D, Köber S, Langer H, Jander S, Jurk K, Frotscher M, Korth C, Bock HH, Elvers M. Loss of Reelin protects mice against arterial thrombosis by impairing integrin activation and thrombus formation under high shear conditions. Cell Signal 2017;40:210-221.
• Schuster AK, Pfeiffer N, Schulz A, Hoehn R, Ponto KA, Wild PS, Blettner M, Beutel ME, Lackner KJ, Münzel T, Mirshahi A. Refractive, corneal and ocular residual astigmatism: distribution in a German population and age-dependency - the Gutenberg health study. Graefes Arch Clin Exp Ophthalmol 2017;255(12):2493-2501.
• Jäckel S, Kiouptsi K, Lillich M, Hendrikx T, Khandagale A, Kollar B, Hörmann N, Reiss C, Subramaniam S, Wilms E, Ebner K, Brühl MV, Rausch P, Baines JF, Haberichter S, Lämmle B, Binder CJ, Jurk K, Ruggeri ZM, Massberg S, Walter U, Ruf W, Reinhardt C. Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2. Blood 2017;130(4):542-553.
• Höhn R, Mirshahi A, Nickels S, Schulz A, Wild PS, Blettner M, Pfeiffer N. Cardiovascular medication and intraocular pressure: results from the Gutenberg Health Study. Br J Ophthalmol 2017;101(12):1633-1637.
• Braenne I, Willenborg C, Tragante V, Kessler T, Zeng L, Reiz B, Kleinecke M, von Ameln S, Willer CJ, Laakso M, Wild PS, Zeller T, Wallentin L, Franks PW, Salomaa V, Dehghan A, Meitinger T, Samani NJ, Asselbergs FW, Erdmann J et al. (2017) A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors. Scientific reports 7: 10252
• Nickels S, Schuster AK, Singer S, Wild PS, Laubert-Reh D, Schulz A, Finger RP, Michal M, Beutel ME, Münzel T, Lackner KJ, Pfeiffer N (2017) The National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) - reference data from the German population-based Gutenberg Health Study (GHS). Health Qual Life Outcomes 15: 156
• Zeller T, Schurmann C, Schramm K, Müller C, Kwon S, Wild PS, Teumer A, Herrington D, Schillert A, Iacoviello L, Kratzer A, Jagodzinski A, Karakas M, Ding J, Neumann JT, Kuulasmaa K, Gieger C, Kacprowski T, Schnabel RB, Roden M et al. (2017) Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. Hypertension 70: 743-750
• Trinchero A, Schotten S, Lämmle B, Pitton MB (2017) May-Thurner syndrome: missed diagnosis and missed early treatment? Hamostaseologie 37: 184-185
• Hubert A, Bochenek ML, Schutz E, Gogiraju R, Münzel T, Schäfer K (2017) Selective Deletion of Leptin Signaling in Endothelial Cells Enhances Neointima Formation and Phenocopies the Vascular Effects of Diet-Induced Obesity in Mice. Arteriosclerosis, thrombosis, and vascular biology 37: 1683-1697
• Schütz E, Bochenek ML, Riehl DR, Bosmann M, Münzel T, Konstantinides S, Schäfer K (2017) Absence of transforming growth factor beta 1 in murine platelets reduces neointima formation without affecting arterial thrombosis. Thrombosis and haemostasis 117: 1782-1797
• Roewe J, Higer M, Riehl DR, Gericke A, Radsak MP, Bosmann M (2017) Neuroendocrine Modulation of IL-27 in Macrophages. Journal of immunology 199(7):2503-2514
• Kamikubo Y, Mendolicchio GL, Zampolli A, Marchese P, Rothmeier AS, Orje JN, Gale AJ, Krishnaswamy S, Gruber A, Ostergaard H, Petersen LC, Ruf W, Ruggeri ZM (2017) Selective factor VIII activation by the tissue factor-factor VIIa-factor Xa complex. Blood 130: 1661-1670
• Alflen A, Prüfer S, Ebner K, Reuter S, Aranda Lopez P, Scharrer I, Banno F, Stassen M, Schild H, Jurk K, Bosmann M, Beckert H, Radsak MP (2017) ADAMTS-13 regulates neutrophil recruitment in a mouse model of invasive pulmonary aspergillosis. Scientific reports 7: 7184
• Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C (2017) Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels. PloS one 12: e0183590
• Kiouptsi K, Gambaryan S, Walter E, Walter U, Jurk K, Reinhardt C (2017) Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation. Sci Rep. 7(1):7621
• Klier M, Gowert NS, Jäckel S, Reinhardt C, Elvers M (2017) Phospholipase D1 is a regulator of platelet-mediated inflammation. Cell Signal 38: 171-181
• Schulz A, Zöller D, Nickels S, Beutel ME, Blettner M, Wild PS, Binder H(2017) Simulation of complex data structures for planning of studies with focus on biomarker comparison. BMC Med Res Methodol 17: 90
• Grechowa I, Horke S, Wallrath A, Vahl CF, Dorweiler B (2017) Human neutrophil elastase induces endothelial cell apoptosis by activating the PERK-CHOP branch of the unfolded protein response. FASEB journal 31: 3868-3881
• Mean M, Limacher A, Stalder O, Angelillo-Scherrer A, Alberio L, Fontana P, Beer HJ, Rodondi N, Lämmle B, Aujesky D (2017) Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients? Am J Med 130: 1220 e17-1220 e22
• Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al-Dabet MM, Manoharan J, Nazir S, Elwakiel A, Bock F, Kohli S, Marquardt A, Sögüt I, Shahzad K, Müller AJ, Esmon CT, Nawroth PP, Reiser J, Chavakis T, Ruf W, Isermann B (2017) Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function. Blood 130: 1445-1455
• Chrysanthopoulou A, Kambas K, Stakos D, Mitroulis I, Mitsios A, Vidali V, Angelidou I, Bochenek M, Arelaki S, Arampatzioglou A, Galani IE, Skendros P, Couladouros EA, Konstantinides S, Andreakos E, Schäfer K, Ritis K (2017) Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation. J Pathol 243: 111-122
• Dentali F, Pegoraro S, Barco S, di Minno MND, Mastroiacovo D, Pomero F, Lodigiani C, Bagna F, Sartori M, Barillari G, Mumoli N, Napolitano M, Passamonti SM, Benedetti R, Ageno W, Di Nisio M (2017) Clinical course of isolated distal deep vein thrombosis in patients with active cancer: a multicenter cohort study. Journal of thrombosis and haemostasis 15: 1757-1763
• Fattahi F, Kalbitz M, Malan EA, Abe E, Jajou L, Huber-Lang MS, Bosmann M, Russell MW, Zetoune FS, Ward PA (2017) Complement-induced activation of MAPKs and Akt during sepsis: role in cardiac dysfunction. FASEB journal 31(9):4129-4139
• Hoeper MM, Lam CS, Vachiery JL, Bauersachs J, Gerges C, Lang IM, Bonderman D, Olsson KM, Gibbs JS, Dorfmuller P, Guazzi M, Galie N, Manes A, Handoko ML, Vonk-Noordegraaf A, Lankeit M, Konstantinides S, Wachter R, Opitz C, Rosenkranz S (2017) Pulmonary hypertension in heart failure with preserved ejection fraction: a plea for proper phenotyping and further research. European heart journal 7;38(38):2869-2873
• Arnold N, Gori T, Schnabel RB, Schulz A, Prochaska JH, Zeller T, Binder H, Pfeiffer N, Beutel M, Espinola-Klein C, Lackner KJ, Blankenberg S, Münzel T, Wild PS (2017) Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis - Data from the Population-based Gutenberg Health Study. Scientific reports 7: 6346
• Keller K, Stelzer K, Ostad MA, Post F (2017) Impact of exaggerated blood pressure response in normotensive individuals on future hypertension and prognosis: Systematic review according to PRISMA guideline. Advances in medical sciences 62: 317-329 
• Rukoyatkina N, Butt E, Subramanian H, Nikolaev VO, Mindukshev I, Walter U, Gambaryan S, Benz PM (2017) Protein kinase A activation by the anti-cancer drugs ABT-737 and thymoquinone is caspase-3-dependent and correlates with platelet inhibition and apoptosis. Cell Death Dis 8: e2898
• Ponto KA, Werner DJ, Wiedemer L, Laubert-Reh D, Schuster AK, Nickels S, Höhn R, Schulz A, Binder H, Beutel M, Lackner KJ, Wild PS, Pfeiffer N, Mirshahi A (2017) Retinal vessel metrics: normative data and their use in systemic hypertension: results from the Gutenberg Health Study. J Hypertens 35: 1635-1645
• Steven S, Oelze M, Hanf A, Kröller-Schön S, Kashani F, Roohani S, Welschof P, Kopp M, Godtel-Armbrust U, Xia N, Li H, Schulz E, Lackner KJ, Wojnowski L, Bottari SP, Wenzel P, Mayoux E, Münzel T, Daiber A (2017) The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats. Redox Biol 13: 370-385
• Rothmeier AS, Marchese P, Langer F, Kamikubo Y, Schaffner F, Cantor J, Ginsberg MH, Ruggeri ZM, Ruf W (2017) Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking. Arteriosclerosis, thrombosis, and vascular biology 37: 1323-1331
• Prochaska JH, Frank B, Nagler M, Lamparter H, Weisser G, Schulz A, Eggebrecht L, Göbel S, Arnold N, Panova-Noeva M, Hermanns I, Pinto A, Konstantinides S, Ten Cate H, Lackner KJ, Münzel T, Espinola-Klein C, Wild PS (2017) Age-related diagnostic value of D-dimer testing and the role of inflammation in patients with suspected deep vein thrombosis. Scientific reports 7: 4591
• Prochaska JH, Göbel S, Keller K, Coldewey M, Ullmann A, Lamparter H, Schulz A, Schinzel H, Bickel C, Lauterbach M, Michal M, Hardt R, Binder H, Espinola-Klein C, Lackner KJ, Ten Cate H, Münzel T, Wild PS (2017) e-Health-based management of patients receiving oral anticoagulation therapy: results from the observational thrombEVAL study. Journal of thrombosis and haemostasis 15: 1375-1385
• Sag CM, Schnelle M, Zhang J, Murdoch CE, Kossmann S, Protti A, Santos CXC, Sawyer G, Zhang X, Mongue-Din H, Richards DA, Brewer AC, Prysyazhna O, Maier LS, Wenzel P, Eaton PJ, Shah AM (2017) Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure. Circulation 135: 2163-2177
• Barco S, Corti M, Trinchero A, Picchi C, Ambaglio C, Konstantinides SV, Dentali F, Barone M (2017) Survival and recurrent venous thromboembolism in patients with first proximal or isolated distal deep vein thrombosis and no pulmonary embolism. Journal of thrombosis and haemostasis 15: 1436-1442
• Kargapolova Y, Levin M, Lackner K, Danckwardt S (2017) sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs. Nucleic Acids Res 45: 6074-6086
• Klok FA, Barco S, Konstantinides SV (2017) External validation of the VTE-BLEED score for predicting major bleeding in stable anticoagulated patients with venous thromboembolism. Thrombosis and haemostasis 117: 1164-1170
• Mumoli N, Barco S, Cei M, Giorgi-Pierfranceschi M, Campanini M, Fontanella A, Ageno W, Dentali F (2017) Prevention and treatment of venous thromboembolism in patients with solid brain neoplasms: results of a survey among Italian physicians. Internal and emergency medicine 12: 437-443
• Sinning C, Ojeda F, Wild PS, Schnabel RB, Schwarzl M, Ohdah S, Lackner KJ, Pfeiffer N, Michal M, Blettner M, Münzel T, Kempf T, Wollert KC, Kuulasmaa K, Blankenberg S, Salomaa V, Westermann D, Zeller T (2017) Midregional proadrenomedullin and growth differentiation factor-15 are not influenced by obesity in heart failure patients. Clinical research in cardiology 106: 401-410
• Barco S, Atema JJ, Coppens M, Serlie MJ, Middeldorp S (2017) Anticoagulants for the prevention and treatment of catheter-related thrombosis in adults and children on parenteral nutrition: a systematic review and critical appraisal. Blood Transfus 15: 369-377
• Steven S, Jurk K, Kopp M, Kröller-Schön S, Mikhed Y, Schwierczek K, Roohani S, Kashani F, Oelze M, Klein T, Tokalov S, Danckwardt S, Strand S, Wenzel P, Münzel T, Daiber A (2017) Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice. British journal of pharmacology 174: 1620-1632
• Beutel ME, Klein EM, Brähler E, Reiner I, Jünger C, Michal M, Wiltink J, Wild PS, Münzel T, Lackner KJ, Tibubos AN (2017) Loneliness in the general population: prevalence, determinants and relations to mental health. BMC psychiatry 17: 97
• Brant LC, Wang N, Ojeda FM, LaValley M, Barreto SM, Benjamin EJ, Mitchell GF, Vasan RS, Palmisano JN, Münzel T, Blankenberg S, Wild PS, Zeller T, Ribeiro AL, Schnabel RB, Hamburg NM (2017) Relations of Metabolically Healthy and Unhealthy Obesity to Digital Vascular Function in Three Community-Based Cohorts: A Meta-Analysis. Journal of the American Heart Association 6
• Marx-Gross S, Laubert-Reh D, Schneider A, Höhn R, Mirshahi A, Münzel T, Wild PS, Beutel ME, Blettner M, Pfeiffer N (2017) The Prevalence of Glaucoma in Young People. Deutsches Arzteblatt international 114: 204-210
• Rose DM, Seidler A, Nübling M, Latza U, Brähler E, Klein EM, Wiltink J, Michal M, Nickels S, Wild PS, König J, Claus M, Letzel S, Beutel ME (2017) Associations of fatigue to work-related stress, mental and physical health in an employed community sample. BMC psychiatry 17: 167
• Schuster AK, Pfeiffer N, Schulz A, Nickels S, Höhn R, Wild PS, Blettner M, Münzel T, Beutel ME, Lackner KJ, Vossmerbaeumer U (2017) The impact of pseudophakia on vision-related quality of life in the general population - The Gutenberg Health Study. Aging  9: 1030-1040
• Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJG, Volker U, Grossmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, Malzahn D, Smith AV, Sundstrom J, Minelli C, Ruggiero D et al. (2017) Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. The Journal of clinical investigation 127: 1798-1812
• Stein J, Steven S, Bros M, Sudowe S, Hausding M, Oelze M, Münzel T, Grabbe S, Reske-Kunz A, Daiber A (2017) Role of Protein Kinase C and Nox2-Derived Reactive Oxygen Species Formation in the Activation and Maturation of Dendritic Cells by Phorbol Ester and Lipopolysaccharide. Oxid Med Cell Longev 2017: 4157213
• Falter T, Schmitt V, Herold S, Weyer V, von Auer C, Wagner S, Hefner G, Beutel M, Lackner K, Lämmle B, Scharrer I (2017) Depression and cognitive deficits as long-term consequences of thrombotic thrombocytopenic purpura. Transfusion 57: 1152-1162
• Lorenz K, Scheller Y, Bell K, Grus F, Ponto KA, Bock F, Cursiefen C, Flach J, Gehring M, Peto T, Silva R, Tal Y, Pfeiffer N (2017) A prospective, randomised, placebo-controlled, double-masked, three-armed, multicentre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma - the STRONG study: study protocol for a randomised controlled trial. Trials 18: 128
• Steven S, Oelze M, Brandt M, Ullmann E, Kröller-Schön S, Heeren T, Tran LP, Daub S, Dib M, Stalleicken D, Wenzel P, Münzel T, Daiber A (2017) Pentaerythritol Tetranitrate In Vivo Treatment Improves Oxidative Stress and Vascular Dysfunction by Suppression of Endothelin-1 Signaling in Monocrotaline-Induced Pulmonary Hypertension. Oxid Med Cell Longev 2017: 4353462
• Luque Ramos A, Ohlmeier C, Enders D, Linder R, Horenkamp-Sonntag D, Prochaska JH, Mikolajczyk R, Garbe E (2017) Initiation and duration of dual antiplatelet therapy after inpatient percutaneous coronary intervention with stent implantation in Germany: An electronic healthcare database cohort study. Z Evid Fortbild Qual Gesundhwes 120: 31-38
• Panova-Noeva M, Arnold N, Hermanns MI, Prochaska JH, Schulz A, Spronk HM, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner KJ, Ten Cate H, Wild PS (2017) Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability. Scientific reports 7: 40229
• Magnussen C, Ojeda FM, Rzayeva N, Zeller T, Sinning CR, Pfeiffer N, Beutel M, Blettner M, Lackner KJ, Blankenberg S, Münzel T, Rabe KF, Wild PS, Schnabel RB, Gutenberg Health Study i (2017) FEV1 and FVC predict all-cause mortality independent of cardiac function - Results from the population-based Gutenberg Health Study. International journal of cardiology 234: 64-68
• de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, [...], Wild PS et al. (2017) Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PloS one 12: e0167742
• Springelkamp H, Iglesias AI, Mishra A, Hohn R, Wojciechowski R, Khawaja AP, Nag A, Wang YX, Wang JJ, Cuellar-Partida G, Gibson J, Bailey JN, Vithana EN, Gharahkhani P, Boutin T, Ramdas WD, Zeller T, Luben RN, Yonova-Doing E, Viswanathan A, […], Wild PS et al. (2017) New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Human molecular genetics 26: 438-453
• Sennblad B, Basu S, Mazur J, Suchon P, Martinez-Perez A, van Hylckama Vlieg A, Truong V, Li Y, Gadin JR, Tang W, Grossman V, de Haan HG, Handin N, Silveira A, Souto JC, Franco-Cereceda A, Morange PE, Gagnon F, Soria JM, Eriksson P, Hamsten A, Maegdefessel L, Rosendaal FR, Wild P, Folsom AR, Tregouet DA, Sabater-Lleal M (2017) Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels. Human molecular genetics 26: 637-649
• Loroch S, Trabold K, Gambaryan S, Reiss C, Schwierczek K, Fleming I, Sickmann A, Behnisch W, Zieger B, Zahedi RP, Walter U, Jurk K (2017) Alterations of the platelet proteome in type I Glanzmann thrombasthenia caused by different homozygous delG frameshift mutations in ITGA2B. Thrombosis and haemostasis 117: 556-569
• Beck F, Geiger J, Gambaryan S, Solari FA, Dell'Aica M, Loroch S, Mattheij NJ, Mindukshev I, Potz O, Jurk K, Burkhart JM, Fufezan C, Heemskerk JW, Walter U, Zahedi RP, Sickmann A (2017) Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition. Blood 129: e1-e12
• Subramaniam S, Jurk K, Hobohm L, Jäckel S, Saffarzadeh M, Schwierczek K, Wenzel P, Langer F, Reinhardt C, Ruf W (2017) Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development. Blood 129: 2291-2302
• Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P (2017) Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension. Sci Transl Med 9
• Reiner MF, Akhmedov A, Stivala S, Keller S, Gaul DS, Bonetti NR, Savarese G, Glanzmann M, Zhu C, Ruf W, Yang Z, Matter CM, Luscher TF, Camici GG, Beer JH (2017) Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression. Cardiovascular research 113: 61-69
• Bochenek ML, Rosinus NS, Lankeit M, Hobohm L, Bremmer F, Schutz E, Klok FA, Horke S, Wiedenroth CB, Münzel T, Lang IM, Mayer E, Konstantinides S, Schäfer K (2017) From thrombosis to fibrosis in chronic thromboembolic pulmonary hypertension. Thrombosis and haemostasis 117: 769-783
• van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, [...] Wild PS, [...] et al. (2017) Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet 100: 51-63
• Panova-Noeva M, Arnold N, Hermanns MI, Prochaska JH, Schulz A, Spronk HM, Binder H, Pfeiffer N, Beutel M, Blankenberg S, Zeller T, Lotz J, Münzel T, Lackner KJ, Ten Cate H, Wild PS (2017) Mean Platelet Volume and Arterial Stiffness - Clinical Relationship and Common Genetic Variability. Scientific reports 7: 40229
• Busch CJ, Hendrikx T, Weismann D, Jäckel S, Walenbergh SM, Rendeiro AF, Weisser J, Puhm F, Hladik A, Göderle L, Papac-Milicevic N, Haas G, Millischer V, Subramaniam S, Knapp S, Bennett KL, Bock C, Reinhardt C, Shiri-Sverdlov R, Binder CJ (2017) Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. Hepatology 65: 1181-1195
• Konstantinides SV, Vicaut E, Danays T, Becattini C, Bertoletti L, Beyer-Westendorf J, Bouvaist H, Couturaud F, Dellas C, Duerschmied D, Empen K, Ferrari E, Galie N, Jimenez D, Kostrubiec M, Kozak M, Kupatt C, Lang IM, Lankeit M, Meneveau N et al. (2017) Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. Journal of the American College of Cardiology 69: 1536-1544
• Müller-Calleja N, Manukyan D, Canisius A, Strand D, Lackner KJ (2017) Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase. Ann Rheum Dis 76: 891-897
• Sinning C, Kempf T, Schwarzl M, Lanfermann S, Ojeda F, Schnabel RB, Zengin E, Wild PS, Lackner KJ, Münzel T, Blankenberg S, Wollert KC, Zeller T, Westermann D (2017) Biomarkers for characterization of heart failure - Distinction of heart failure with preserved and reduced ejection fraction. International journal of cardiology 227: 272-277
• Faller N, Limacher A, Mean M, Righini M, Aschwanden M, Beer JH, Frauchiger B, Osterwalder J, Kucher N, Lämmle B, Cornuz J, Angelillo-Scherrer A, Matter CM, Husmann M, Banyai M, Staub D, Mazzolai L, Hugli O, Rodondi N, Aujesky D (2017) Predictors and Causes of Long-Term Mortality in Elderly Patients with Acute Venous Thromboembolism: A Prospective Cohort Study. Am J Med 130: 198-206
• Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H, International Working Group for Thrombotic Thrombocytopenic P (2017) Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies. Journal of thrombosis and haemostasis 15: 312-322
• Barco S, Picchi C, Trinchero A, Middeldorp S, Coppens M (2017) Safety of prothrombin complex concentrate in healthy subjects. Br J Haematol 176: 664-666
• Keller K, von Bardeleben RS, Ostad MA, Hobohm L, Münzel T, Konstantinides S, Lankeit M (2017) Temporal Trends in the Prevalence of Infective Endocarditis in Germany Between 2005 and 2014. Am J Cardiol 119: 317-322

Reviews 2017

• Lankeit M. Always think of the right ventricle, even in "low-risk" pulmonary embolism. Eur Respir J 2017;50(6).
• Lankeit M, Keller K, Tschöpe C, Pieske B. [Medicinal treatment of tricuspid valve regurgitation]. Herz 2017;42(7):634-643.
• Schönfelder T, Jäckel S, Wenzel P (2017) Mouse models of deep vein thrombosis. Gefasschirurgie 22: 28-33
• Schulman S, Ageno W, Konstantinides SV (2017) Venous thromboembolism: Past, present and future. Thrombosis and haemostasis 117: 1219-1229
• Schäfer K, Drosos I, Konstantinides S (2017) Perivascular adipose tissue: epiphenomenon or local risk factor? Int J Obes 41: 1311-1323
• Lackner KJ, Manukyan D, Müller-Calleja N (2017) Pathophysiological insights into the antiphospholipid syndrome. Hamostaseologie 37: 202-207
• Jurk K (2017) Platelet granules - secretory and secretive. Hamostaseologie 37(3):208-210
• Lutz J, Jurk K, Schinzel H (2017) Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations. Int J Nephrol Renovasc Dis 10: 135-143
• Konstantinides SV (2017) Diagnosis of pulmonary embolism: progress after many YEARS. Lancet 390: 210-211
• Lutz J, Jurk K (2017) Antiplatelet Agents and Anticoagulants in Patients with Chronic Kidney Disease - from Pathophysiology to Clinical Practice. Current pharmaceutical design 23: 1366-1376
• Scholz-Kreisel P, Spix C, Blettner M, Eckerle S, Faber J, Wild P, Merzenich H, Hennewig U (2017) Prevalence of cardiovascular late sequelae in long-term survivors of childhood cancer: A systematic review and meta-analysis. Pediatr Blood Cancer 64
• Lackner KJ, Manukyan D, Müller-Calleja N (2017) Endosomal Redox Signaling in the Antiphospholipid Syndrome. Curr Rheumatol Rep 19: 20
• Kremer Hovinga JA, Coppo P, Lämmle B, Moake JL, Miyata T, Vanhoorelbeke K (2017) Thrombotic thrombocytopenic purpura. Nat Rev Dis Primers 3: 17020
• Barco S, Konstantinides SV (2017) Catheter-directed thrombolysis for acute pulmonary embolism: Where do we stand? Lung India 34: 221-222
• Barco S, Konstantinides SV (2017) Risk-adapted management of pulmonary embolism. Thrombosis research 151 Suppl 1: S92-S96
• Wenzel P, Kossmann S, Münzel T, Daiber A (2017) Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species. Free Radic Biol Med 
• Lagrange J, Kossmann S, Wenzel P (2017) Assessment of Vascular Dysfunction and Inflammation Induced by Angiotensin II in Mice. Methods Mol Biol 1559: 439-453
• Konstantinides SV, Barco S (2017) Systemic Thrombolytic Therapy for Acute Pulmonary Embolism: Who Is a Candidate? Semin Respir Crit Care Med 38: 56-65
• Pagel O, Walter E, Jurk K, Zahedi RP (2017) Taking the stock of granule cargo: Platelet releasate proteomics. Platelets 28: 119-128
• Gori T, Grünewald J (2017) Clinical career and research: are they mutually exclusive? European heart journal 38: 72-74

Editorials und Fachbeiträge 2017

• Konstantinides SV. The Elusive Evidence for Inferior Vena Cava Filters to Prevent Pulmonary Embolism. J Am Coll Cardiol 2017;70(13):1598-1600.
• Reinhardt C (2017) GAS6: Pouring GASoline Into the Inflammatory Inferno of Venous Thrombosis. Arteriosclerosis, thrombosis, and vascular biology 37: 1263-1265
• Ruf W, Preissner KT (2017) State of the Art 2017. Journal of thrombosis and haemostasis 15: 1239
• Lämmle B (2017) Opana ER-induced thrombotic microangiopathy. Blood 129: 808-809

Originalartikel 2016

• Yost CC, Schwertz H, Cody MJ, Wallace JA, Campbell RA, Vieira-de-Abreu A, Araujo CV, Schubert S, Harris ES, Rowley JW, Rondina MT, Fulcher JM, Koening CL, Weyrich AS, Zimmerman GA (2016) Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation. The Journal of clinical investigation 126: 3783-3798
• Klok FA, Hösel V, Clemens A, Yollo WD, Tilke C, Schulman S, Lankeit M, Konstantinides SV (2016) Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. The European respiratory journal 48: 1369-1376
• Barco S, Heuschen CB, Salman B, Brekelmans MP, Serlie MJ, Middeldorp S, Coppens M (2016) Home parenteral nutrition-associated thromboembolic and bleeding events: results of a cohort study of 236 individuals. Journal of thrombosis and haemostasis 14: 1364-73
• Barco S, Woersching AL, Spyropoulos AC, Piovella F, Mahan CE (2016) European Union-28: An annualised cost-of-illness model for venous thromboembolism. Thrombosis and haemostasis 115: 800-8
• Jankowiak S, Backé E, Liebers F, Schulz A, Hegewald J, Garthus-Niegel S, Nübling M, Blankenberg S, Pfeiffer N, Lackner KJ, Beutel M, Blettner M, Münzel T, Wild PS, Seidler A, Letzel S, Latza U (2016) Current and cumulative night shift work and subclinical atherosclerosis: results of the Gutenberg Health Study. International archives of occupational and environmental health 89: 1169-1182
• Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, Moretta A, Capaul R, Zbinden A, Ferlazzo G, Malmberg KJ, Chijioke O, Munz C (2016) Cognate HLA absence in trans diminishes human NK cell education. The Journal of clinical investigation 126: 3772-3782
• Schwarzl M, Ojeda F, Zeller T, Seiffert M, Becher PM, Münzel T, Wild PS, Blettner M, Lackner KJ, Pfeiffer N, Beutel ME, Blankenberg S, Westermann D (2016) Risk factors for heart failure are associated with alterations of the LV end-diastolic pressure-volume relationship in non-heart failure individuals: data from a large-scale, population-based cohort. European heart journal 37: 1807-14
• Kohli S, Ranjan S, Hoffmann J, Kashif M, Daniel EA, Al-Dabet MM, Bock F, Nazir S, Huebner H, Mertens PR, Fischer KD, Zenclussen AC, Offermanns S, Aharon A, Brenner B, Shahzad K, Ruebner M, Isermann B (2016) Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts. Blood 128: 2153-2164
• Mirshahi A, Ponto KA, Laubert-Reh D, Rahm B, Lackner KJ, Binder H, Pfeiffer N, Unterrainer JM (2016) Myopia and Cognitive Performance: Results From the Gutenberg Health Study. Invest Ophthalmol Vis Sci 57: 5230-5236
• Elflein HM, Rudy M, Lorenz K, Ponto KA, Scheurich A, Pitz S (2016) Charles Bonnet's syndrome: not only a condition of the elderly. Graefes Arch Clin Exp Ophthalmol 254: 1637-42
• Beutel ME, Jünger C, Klein EM, Wild P, Lackner KJ, Blettner M, Banerjee M, Michal M, Wiltink J, Brahler E (2016) Depression, anxiety and suicidal ideation among 1(st) and 2(nd) generation migrants - results from the Gutenberg health study. BMC psychiatry 16: 288
• Nagler M, Kremer Hovinga JA, Alberio L, Peter-Salonen K, von Tengg-Kobligk H, Lottaz D, Neerman-Arbez M, Lämmle B (2016) Thromboembolism in patients with congenital afibrinogenaemia. Long-term observational data and systematic review. Thrombosis and haemostasis 116: 722-32
• Luther N, Shahneh F, Brähler M, Krebs F, Jäckel S, Subramaniam S, Stanger C, Schönfelder T, Kleis-Fischer B, Reinhardt C, Probst HC, Wenzel P, Schäfer K, Becker C (2016) Innate Effector-Memory T Cell Activation Regulates Post-Thrombotic Vein Wall Inflammation and Thrombus Resolution. Circ Res 
• Elbaz H, Peto T, Butsch C, Orouji E, Laubert-Reh D, Ponto KA, Binder H, Pfeiffer N, Mirshahi A (2016) PREVALENCE AND ASSOCIATIONS OF MYELINATED RETINAL NERVE FIBERS: Results From the Population-Based Gutenberg Health Study. Retina
• Gogiraju R, Schroeter MR, Bochenek ML, Hubert A, Münzel T, Hasenfuss G, Schäfer K (2016) Endothelial deletion of protein tyrosine phosphatase-1B protects against pressure overload-induced heart failure in mice. Cardiovascular research 111: 204-16
• Krüger M, Amort J, Wilgenbus P, Helmstädter JP, Grechowa I, Ebert J, Tenzer S, Moergel M, Witte I, Horke S (2016) The anti-apoptotic PON2 protein is Wnt/beta-catenin-regulated and correlates with radiotherapy resistance in OSCC patients. Oncotarget 
• Benz PM, Laban H, Zink J, Günther L, Walter U, Gambaryan S, Dib K (2016) Vasodilator-Stimulated Phosphoprotein (VASP)-dependent and -independent pathways regulate thrombin-induced activation of Rap1b in platelets. Cell Commun Signal 14: 21
• Gambaryan S, Subramanian H, Kehrer L, Mindukshev I, Sudnitsyna J, Reiss C, Rukoyatkina N, Friebe A, Sharina I, Martin E, Walter U (2016) Erythrocytes do not activate purified and platelet soluble guanylate cyclases even in conditions favourable for NO synthesis. Cell Commun Signal 14: 16
• Keller K, Beule J, Balzer JO, Dippold W (2016) Right bundle branch block and SQ-type patterns for risk stratification in acute pulmonary embolism. Journal of electrocardiology 
• Keller K, Beule J, Balzer JO, Dippold W (2016) Syncope and collapse in acute pulmonary embolism. The American journal of emergency medicine 
• Keller K, Stelzer K, Münzel T, Ostad MA (2016) Hypertension is strongly associated with false-positive bicycle exercise stress echocardiography testing results. Blood pressure: 1-9
• Stark K, Philippi V, Stockhausen S, Busse J, Antonelli A, Miller M, Schubert I, Hoseinpour P, Chandraratne S, von Brühl ML, Gärtner F, Lorenz M, Agresti A, Coletti R, Antoine DJ, Heermann R, Jung K, Reese S, Laitinen I, Schwaiger M, Walch A, Sperandio M, Nawroth PP, Reinhardt C, Jäckel S, Bianchi ME, Massberg S. (2016) Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice. Blood 
• Baum C, Ojeda FM, Wild PS, Rzayeva N, Zeller T, Sinning CR, Pfeiffer N, Beutel M, Blettner M, Lackner KJ, Blankenberg S, Münzel T, Rabe KF, Schnabel RB, Gutenberg Health Study i (2016) Subclinical impairment of lung function is related to mild cardiac dysfunction and manifest heart failure in the general population. International journal of cardiology 218: 298-304
• Beutel ME, Jünger C, Klein EM, Wild P, Lackner K, Blettner M, Binder H, Michal M, Wiltink J, Brähler E, Münzel T (2016) Noise Annoyance Is Associated with Depression and Anxiety in the General Population- The Contribution of Aircraft Noise. PloS one 11: e0155357
• Blankenberg S, Salomaa V, Makarova N, Ojeda F, Wild P, Lackner KJ, Jorgensen T, Thorand B, Peters A, Nauck M, Petersmann A, Vartiainen E, Veronesi G, Brambilla P, Costanzo S, Iacoviello L, Linden G, Yarnell J, Patterson CC, Everett BM et al. (2016) Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium. European heart journal 
• Garthus-Niegel S, Hegewald J, Seidler A, Nubling M, Espinola-Klein C, Liebers F, Wild PS, Latza U, Letzel S (2016) The Gutenberg health study: associations between occupational and private stress factors and work-privacy conflict. Bmc Public Health 16: 192
• Garthus-Niegel S, Nubling M, Letzel S, Hegewald J, Wagner M, Wild PS, Blettner M, Zwiener I, Latza U, Jankowiak S, Liebers F, Seidler A (2016) Development of a mobbing short scale in the Gutenberg Health Study. International archives of occupational and environmental health 89: 137-46
• Ghiassian SD, Menche J, Chasman DI, Giulianini F, Wang R, Ricchiuto P, Aikawa M, Iwata H, Müller C, Zeller T, Sharma A, Wild P, Lackner K, Singh S, Ridker PM, Blankenberg S, Barabasi AL, Loscalzo J (2016) Endophenotype Network Models: Common Core of Complex Diseases. Scientific reports 6: 27414
• Kaller CP, Debelak R, Kostering L, Egle J, Rahm B, Wild PS, Blettner M, Beutel ME, Unterrainer JM (2016) Assessing Planning Ability Across the Adult Life Span: Population-Representative and Age-Adjusted Reliability Estimates for the Tower of London (TOL-F). Archives of clinical neuropsychology 31: 148-64 
• Manukyan D, Rossmann H, Schulz A, Zeller T, Pfeiffer N, Binder H, Münzel T, Beutel ME, Müller-Calleja N, Wild PS, Lackner KJ (2016) Distribution of antiphospholipid antibodies in a large population-based German cohort. Clinical chemistry and laboratory medicine 54: 1663-70
• Müller-Calleja N, Rossmann H, Müller C, Wild P, Blankenberg S, Pfeiffer N, Binder H, Beutel ME, Manukyan D, Zeller T, Lackner KJ (2016) Antiphospholipid antibodies in a large population-based cohort: genome-wide associations and effects on monocyte gene expression. Thrombosis and haemostasis 116: 115-23
• Müller C, Schillert A, Rothemeier C, Tregouet DA, Proust C, Binder H, Pfeiffer N, Beutel M, Lackner KJ, Schnabel RB, Tiret L, Wild PS, Blankenberg S, Zeller T, Ziegler A (2016) Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data. PloS one 11: e0156594
• Ponto KA, Koenig J, Peto T, Lamparter J, Raum P, Wild PS, Lackner KJ, Pfeiffer N, Mirshahi A (2016) Prevalence of diabetic retinopathy in screening-detected diabetes mellitus: results from the Gutenberg Health Study (GHS). Diabetologia 59: 1913-9
• Schuster AK, Pfeiffer N, Nickels S, Schulz A, Höhn R, Wild PS, Binder H, Münzel T, Beutel ME, Vossmerbaeumer U (2016) Distribution of Anterior Chamber Angle Width and Correlation With Age, Refraction, and Anterior Chamber Depth-The Gutenberg Health Study. Invest Ophthalmol Vis Sci 57: 3740-6
• Unterrainer J, Michal M, Rahm B, Hadzibegovic J, Wild PS, Schulz A, Münzel T, Blettner M, Lackner K, Pfeiffer N, Blankenberg S, Denollet J, Beutel ME (2016) Association of Type D personality with cognitive functioning in individuals with and without cardiovascular disease - The Gutenberg Health Study. International journal of cardiology 214: 256-61
• Becattini C, Agnelli G, Lankeit M, Masotti L, Pruszczyk P, Casazza F, Vanni S, Nitti C, Kamphuisen P, Vedovati MC, De Natale MG, Konstantinides S (2016) Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model. The European respiratory journal 
• Bleker SM, Buchmuller A, Chauleur C, Ainle FN, Donnelly J, Verhamme P, Jacobsen AF, Ganzevoort W, Prins M, Beyer-Westendorf J, DeSancho M, Konstantinides S, Pabinger I, Rodger M, Decousus H, Middeldorp S (2016) Low-molecular-weight heparin to prevent recurrent venous thromboembolism in pregnancy: Rationale and design of the Highlow study, a randomised trial of two doses. Thrombosis research 144: 62-68
• Drosos I, Chalikias G, Pavlaki M, Kareli D, Epitropou G, Bougioukas G, Mikroulis D, Konstantinou F, Giatromanolaki A, Ritis K, Münzel T, Tziakas D, Konstantinides S, Schäfer K (2016) Differences between perivascular adipose tissue surrounding the heart and the internal mammary artery: possible role for the leptin-inflammation-fibrosis-hypoxia axis. Clinical research in cardiology : official journal of the German Cardiac Society 
• Kaymaz C, Öztürk S, Akbal Ö, Tanboga IH, Yilmaz F, Poci N, Türkday S, Hakgör A, Yildiz C, Aktemur T, Özdemir N, Konstantinides S (2016) Ultrasound-Assisted Catheter-Directed Thrombolysis in High-Risk and Intermediate-High-Risk Pulmonary Embolism: Results From a Single-Center Cohort. Angiology 
• Klok FA, Hösel V, Clemens A, Yollo WD, Tilke C, Schulman S, Lankeit M, Konstantinides SV (2016) Prediction of bleeding events in patients with venous thromboembolism on stable anticoagulation treatment. The European respiratory journal 
• Konstantinides SV, Barco S, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Heydenreich N, Hoeper MM, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C et al. (2016) Late outcomes after acute pulmonary embolism: rationale and design of FOCUS, a prospective observational multicenter cohort study. Journal of thrombosis and thrombolysis 
• Brandt M, Garlapati V, Oelze M, Sotiriou E, Knorr M, Kröller-Schön S, Kossmann S, Schönfelder T, Morawietz H, Schulz E, Schultheiss HP, Daiber A, Münzel T, Wenzel P (2016) NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy. Scientific reports 6: 32554
• Karbach SH, Schönfelder T, Brandao I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P (2016) Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction. Journal of the American Heart Association 5
• Steven S, Jurk K, Kopp M, Kröller-Schön S, Mikhed Y, Schwierczek K, Roohani S, Kashani F, Oelze M, Klein T, Tokalov S, Danckwardt S, Strand S, Wenzel P, Münzel T, Daiber A (2016) Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice. British journal of pharmacology
• Barco S, Lankeit M, Binder H, Schellong S, Christ M, Beyer-Westendorf J, Duerschmied D, Bauersachs R, Empen K, Held M, Schwaiblmair M, Fonseca C, Jimenez D, Becattini C, Quitzau K, Konstantinides S. Home treatment of patients with low-risk pulmonary embolism with the oral factor Xa inhibitor rivaroxaban. Rationale and design of the HoT-PE Trial. Thrombosis and haemostasis 116. 2016.
• Ramuschkat M, Appelbaum S, Atzler D, Zeller T, Bauer C, Ojeda FM, Sinning CR, Hoffmann B, Lackner KJ, Boger RH, Wild PS, Münzel T, Blankenberg S, Schwedhelm E, Schnabel RB, Gutenberg Health Study I. ADMA, subclinical changes and atrial fibrillation in the general population. International journal of cardiology 203:640-646. 2016.
• Teumer A, Tin A, Sorice R, […], Wild PS, […], Fox CS, Pattaro C, Kottgen A. Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes. Diabetes 65:803-817. 2016.
• Baum C, Johannsen SS, Zeller T, Atzler D, Ojeda FM, Wild PS, Sinning CR, Lackner KJ, Gori T, Schwedhelm E, Boger RH, Blankenberg S, Münzel T, Schnabel RB, Gutenberg Health Study i. ADMA and arginine derivatives in relation to non-invasive vascular function in the general population. Atherosclerosis 244:149-156. 2016.
• Pattaro C, Teumer A, Gorski M, […], Wild PS, […], Kottgen A, Kao WH, Fox CS. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature communications 7:10023. 2016.
• de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, […], Smith NL, Strachan DP, Dehghan A. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Human molecular genetics 25:358-370. 2016.
• Xia N, Horke S, Habermeier A, Closs EI, Reifenberg G, Gericke A, Mikhed Y, Münzel T, Daiber A, Förstermann U, Li H. Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice. Arteriosclerosis, thrombosis, and vascular biology 36:78-85. 2016.
• Koc M, Kostrubiec M, Elikowski W, Meneveau N, Lankeit M, Grifoni S, Kuch-Wocial A, Petris A, Zaborska B, Stefanovic BS, Hugues T, Torbicki A, Konstantinides S, Pruszczyk P, Ri HI. Outcome of patients with right heart thrombi: the Right Heart Thrombi European Registry. The European respiratory journal 47:869-875. 2016.
• Hobohm L, Hellenkamp K, Hasenfuss G, Münzel T, Konstantinides S, Lankeit M. Comparison of risk assessment strategies for not-high-risk pulmonary embolism. The European respiratory journal 47:1170-1178. 2016.
• Jimenez D, Lobo JL, Fernandez-Golfin C, Portillo AK, Nieto R, Lankeit M, Konstantinides S, Prandoni P, Muriel A, Yusen RD, investigators P. Effectiveness of prognosticating pulmonary embolism using the ESC algorithm and the Bova score. Thrombosis and haemostasis 115:827-834. 2016.
• Manukyan D, Müller-Calleja N, Jäckel S, Luchmann K, Monnikes R, Kiouptsi K, Reinhardt C, Jurk K, Walter U, Lackner KJ. Cofactor-independent human antiphospholipid antibodies induce venous thrombosis in mice. Journal of thrombosis and haemostasis 14:1011-1020. 2016.
• von Krogh AS, Quist-Paulsen P, Waage A, Langseth OO, Thorstensen K, Brudevold R, Tjonnfjord GE, Largiader CR, Lämmle B, Kremer Hovinga JA. High prevalence of hereditary thrombotic thrombocytopenic purpura in central Norway: from clinical observation to evidence. Journal of thrombosis and haemostasis 14:73-82. 2016.
• Segna D, Mean M, Limacher A, Baumgartner C, Blum MR, Beer JH, Kucher N, Righini M, Matter CM, Frauchiger B, Cornuz J, Aschwanden M, Banyai M, Osterwalder J, Husmann M, Egloff M, Staub D, Lämmle B, Angelillo-Scherrer A, Aujesky D, Rodondi N. Association between thyroid dysfunction and venous thromboembolism in the elderly: a prospective cohort study. Journal of thrombosis and haemostasis. 14: 685-94. 2016.
• Insam C, Mean M, Limacher A, Angelillo-Scherrer A, Aschwanden M, Banyai M, Beer JH, Bounameaux H, Egloff M, Frauchiger B, Husmann M, Kucher N, Lämmle B, Matter C, Osterwalder J, Righini M, Staub D, Rodondi N, Aujesky D. Anticoagulation Management Practices and Outcomes in Elderly Patients with Acute Venous Thromboembolism: A Clinical Research Study. PloS one 11:e0148348. 2016.
• Fan X, Kremer Hovinga JA, Shirotani-Ikejima H, Eura Y, Hirai H, Honda S, Kokame K, Taleghani MM, von Krogh AS, Yoshida Y, Fujimura Y, Lämmle B, Miyata T. Genetic variations in complement factors in patients with congenital thrombotic thrombocytopenic purpura with renal insufficiency. International journal of hematology 103:283-291. 2016.

Reviews 2016

• Kiouptsi K, Reinhardt C (2016) Protein disulfide-isomerase - a trigger of tissue factor-dependent thrombosis. Clin Hemorheol Microcirc 64: 279-286
• Barco S (2016) Edoxaban for pulmonary embolism with right ventricular dysfunction. Lancet Haematol 3: e405-6
• Barco S, Serlie MJ, Coppens M (2016) Primary thromboprophylaxis for adult patients on home parenteral nutrition: A comment on the 2016 ESPEN guideline. Clin Nutr 35: 1579-1580
• Mahan CE, Barco S, Spyropoulos AC (2016) Cost-of-illness model for venous thromboembolism. Thrombosis research 145: 130-2
• Bochenek ML, Schutz E, Schäfer K (2016) Endothelial cell senescence and thrombosis: Ageing clots. Thrombosis research 147: 36-45
• Daiber A, Steven S, Weber A, Shuvaev VV, Muzykantov VR, Laher I, Li H, Lamas S, Münzel T (2016) Targeting vascular (endothelial) dysfunction. British journal of pharmacology
• Garn H, Bahn S, Baune BT, Binder EB, Bisgaard H, Chatila TA, Chavakis T, Culmsee C, Dannlowski U, Gay S, Gern J, Haahtela T, Kircher T, Müller-Ladner U, Neurath MF, Preissner KT, Reinhardt C, Rook G, Russell S, Schmeck B et al. (2016) Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. J Allergy Clin Immunol 138: 47-56
• Harjola VP, Mebazaa A, Celutkiene J, Bettex D, Bueno H, Chioncel O, Crespo-Leiro MG, Falk V, Filippatos G, Gibbs S, Leite-Moreira A, Lassus J, Masip J, Mueller C, Mullens W, Naeije R, Nordegraaf AV, Parissis J, Riley JP, Ristic A et al. (2016) Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology. European journal of heart failure 18: 226-41
• Konstantinides SV (2016) Trends in pregnancy outcomes in patients with pulmonary hypertension: still a long way to go. European journal of heart failure 18: 1129-31
• Sista AK, Goldhaber SZ, Vedantham S, Kline JA, Kuo WT, Kahn SR, Kabrhel C, McLaughlin VV, White SB, Kim NH, Gray M, Simon MA, Benenati JF, Misra S, Sterling KM, Kee ST, Konstantinides SV, Jaff MR, Kearon C (2016) Research Priorities in Submassive Pulmonary Embolism: Proceedings from a Multidisciplinary Research Consensus Panel. Journal of vascular and interventional radiology : JVIR 27: 787-94
• Ogorodnikov, A., Y. Kargapolova and S. Danckwardt (2016). Processing and transcriptome expansion at the mRNA 3' end in health and disease: finding the right end. Pflugers Arch 468(6): 993-1012.
• Ruf, W. (2016). Hemostasis keeps the stem cell niche in order. Blood 128(8): 1027-1029.
• Ruf W, Rothmeier AS, Graf C. Targeting clotting proteins in cancer therapy - progress and challenges. Thrombosis research 140 Suppl 1:S1-7. 2016.
• Ward PA, Fattahi F, Bosmann M. New Insights into Molecular Mechanisms of Immune Complex-Induced Injury in Lung. Frontiers in immunology 7:86. 2016.
• Krenzlin H, Lorenz V, Danckwardt S, Kempski O, Alessandri B. The Importance of Thrombin in Cerebral Injury and Disease. International journal of molecular sciences 17. 2016.
• Gur-Cohen S, Kollet O, Graf C, Esmon CT, Ruf W, Lapidot T. Regulation of long-term repopulating hematopoietic stem cells by EPCR/PAR1 signaling. Annals of the New York Academy of Sciences. 2016.
• Konstantinides SV, Barco S, Lankeit M, Meyer G. Management of Pulmonary Embolism: An Update. Journal of the American College of Cardiology 67:976-990. 2016.
• Lankeit M, Held M. Incidence of venous thromboembolism in COPD: linking inflammation and thrombosis? The European respiratory journal 47:369-373. 2016.
• Lämmle B. Thrombotic microangiopathy: Caplacizumab accelerates resolution of acute acquired TTP. Nature reviews. Nephrology 12:259-260. 2016.

Editorials und Fachbeiträge 2016

• Konstantinides SV. Trends in incidence versus case fatality rates of pulmonary embolism: Good news or bad news? Thrombosis and haemostasis 115:233-235. 2016.
• Konstantinides SV. Trends in Pulmonary Embolism Outcomes: Are We Really Making Progress? Journal of the American College of Cardiology 67:171-173. 2016.

• Isth Steering Committee for World Thrombosis Day (2016) Venous thromboembolism: A Call for risk assessment in all hospitalised patients. Thrombosis and haemostasis 116: 777-779
• Wilkens H, Konstantinides S, Lang I, Bunck AC, Gerges M, Gerhardt F, Grgic A, Grohe C, Guth S, Held M, Hinrichs J, Hoeper MM, Klepetko W, Kramm T, Kruger U, Lankeit M, Meyer BC, Olsson KM, Schafers HJ, Schmidt M et al. (2016) [Chronic thromboembolic pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016]. Deutsche medizinische Wochenschrift 141: S62-S69
• Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, Gonzalez-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH et al. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. European heart journal

Originalartikel 2015

• Atzler D, Appelbaum S, Cordts K, Ojeda FM, Wild PS, Münzel T, Blankenberg S, Boger RH, Blettner M, Beutel ME, Pfeiffer N, Zeller T, Lackner KJ, Schwedhelm E. Reference intervals of plasma homoarginine from the German Gutenberg Health Study. Clinical chemistry and laboratory medicine. 2015.
• Pfützner A, Hermanns I, Ramljak S, Demircik F, Pfützner AH, Kann PH, Weber MM. Elevated Intact Proinsulin Levels During an Oral Glucose Challenge Indicate Progressive ss-Cell Dysfunction and May Be Predictive for Development of Type 2 Diabetes. Journal of diabetes science and technology 9:1307-1312. 2015.
• Hauser F, Rossmann H, Laubert-Reh D, Wild PS, Zeller T, Müller C, Neuwirth S, Blankenberg S, Lackner KJ. Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene? Genes and immunity 16:571-575. 2015.
• Zeller T, Haase T, Müller C, Riess H, Lau D, Zeller S, Krause J, Baumert J, Pless O, Dupuis J, Wild PS, Eleftheriadis M, Waldenberger M, Zeilinger S, Ziegler A, Peters A, Tiret L, Proust C, Marzi C, Münzel T, Strauch K, Prokisch H, Lackner KJ, Herder C, Thorand B, Benjamin EJ, Blankenberg S, Koenig W, Schnabel RB. Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels. Circulation. Cardiovascular genetics 8:717-726. 2015.
• Homuth G, Wahl S, Muller C, [...], Wild PS, Ziegler A, Volker U, Prokisch H, Zeller T. Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts. BMC medical genomics 8:65. 2015. 
• Hasibeder A, Stein P, Brandwijk R, Schild H, Radsak MP. Evaluation and Validation of the Detection of soluble Triggering Receptor Expressed on Myeloid Cells 1 by Enzyme-linked immunosorbent Assay. Scientific reports 5:15381. 2015.
• Liang HP, Kerschen EJ, Basu S, Hernandez I, Zogg M, Jia S, Hessner MJ, Toso R, Rezaie AR, Fernandez JA, Camire RM, Ruf W, Griffin JH, Weiler H. Coagulation factor V mediates inhibition of tissue factor signaling by activated protein C in mice. Blood 126:2415-2423. 2015.
• Schnabel RB, Wild PS, Prochaska JH, Ojeda FM, Zeller T, Rzayeva N, Ebrahim A, Lackner KJ, Beutel ME, Pfeiffer N, Sinning CR, Oertelt-Prigione S, Regitz-Zagrosek V, Binder H, Münzel T, Blankenberg S, Gutenberg Health Study I. Sex Differences in Correlates of Intermediate Phenotypes and Prevalent Cardiovascular Disease in the General Population. Frontiers in cardiovascular medicine 2:15. 2015.
• Cohen SG, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, Golan K, Kalinkovich A, Ledergor G, Wong E, Niemeyer E, Porat Z, Erez A, Sagi I, Esmon CT, Ruf W, Lapidot T. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nature medicine. 21:1307-1317. 2015.
• Hellenkamp K, Schwung J, Rossmann H, Kaeberich A, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Risk stratification of normotensive pulmonary embolism: prognostic impact of copeptin. The European respiratory journal. 2015.
• Klok FA, Dzikowska-Diduch O, Kostrubiec M, Vliegen HW, Pruszczyk P, Hasenfuss G, Huisman MV, Konstantinides S, Lankeit M. Derivation of a clinical prediction score for chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. Journal of thrombosis and haemostasis : JTH. 2015.
• Ponto KA, Binder H, Diana T, Matheis N, Otto AF, Pitz S, Pfeiffer N, Kahaly GJ. Prevalence, Phenotype, and Psychosocial Well-Being in Euthyroid/Hypothyroid Thyroid-Associated Orbitopathy. Thyroid. 25:942-948. 2015.
• Keller K, Prochaska JH, Coldewey M, Gobel S, Ullmann A, Jünger C, Lamparter H, Ariza L, Bickel C, Lauterbach M, Konstantinides S, Rostock T, Münzel T, Wild PS. History of deep vein thrombosis is a discriminator for concomitant atrial fibrillation in pulmonary embolism. Thrombosis research 136:899-906. 2015.
• Panova-Noeva M, Schulz A, Hermanns I, Grossmann V, Pefani E, Spronk H, Laubert-Reh D, Binder H, Beutel M, Pfeiffer N, Blankenberg S, Zeller T, Münzel T, Lackner KJ, Ten Cate H, Wild PS. Sex specific differences in genetic and non-genetic determinants of mean platelet volume: results from the Gutenberg Health Study. Blood. 2015.
• Larmann J, Jurk K, Janssen H, Müller M, Herzog C, Lorenz A, Schmitz M, Nofer JR, Theilmeier G. Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice. PloS one 10:e0131854. 2015.
• Wenzel P, Rossmann H, Müller C, Kossmann S, Oelze M, Schulz A, Arnold N, Simsek C, Lagrange J, Klemz R, Schönfelder T, Brandt M, Karbach SH, Knorr M, Finger S, Neukirch C, Häuser F, Beutel ME, Kröller-Schön S, Schulz E, Schnabel RB, Lackner K, Wild PS, Zeller T, Daiber A, Blankenberg S, Münzel T. Heme oxygenase-1 suppresses a pro-inflammatory phenotype in monocytes and determines endothelial function and arterial hypertension in mice and humans. European heart journal. 2015.
• Reiss C, Mindukshev I, Bischoff V, Subramanian H, Kehrer L, Friebe A, Stasch JP, Gambaryan S, Walter U. The sGC stimulator Riociguat inhibits platelet function in washed platelets but not in whole blood. British journal of pharmacology, 2015.
• Larmann J, Jurk K, Janssen H, Müller M, Herzog C, Lorenz A, Schmitz M, Nofer JR, Theilmeier G. Hepatic Overexpression of Soluble Urokinase Receptor (uPAR) Suppresses Diet-Induced Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR-/-) Mice. PloS one. 10:e0131854, 2015.
• Jacobsen C, Oechsle K, Hauschild J, Steinemann G, Spath B, Bokemeyer C, Ruf W, Honecker F, Langer F. Regulation of tissue factor in NT2 germ cell tumor cells by cisplatin chemotherapy. Thrombosis research, 2015.
• Reiss C, Mindukshev I, Bischoff V, Subramanian H, Kehrer L, Friebe A, Stasch JP, Gambaryan S, Walter U. The sGC stimulator Riociguat inhibits platelet function in washed platelets but not in whole blood. British journal of pharmacology, 2015.
• Höhn R, Kottler U, Peto T, Blettner M, Münzel T, Blankenberg S, Lackner KJ, Beutel M, Wild PS, Pfeiffer N. The ophthalmic branch of the Gutenberg Health Study: study design, cohort profile and self-reported diseases. PloS one. 10:e0120476, 2015.
• Elflein HM, Fresenius S, Lamparter J, Pitz S, Pfeiffer N, Binder H, Wild P, Mirshahi A. The prevalence of amblyopia in Germany: data from the prospective, population-based Gutenberg Health Study. Deutsches Ärzteblatt international 112:338-344, 2015.
• Ding J, Reynolds LM, Zeller T, Müller C, Mstat KL, Nicklas BJ, Kritchevsky SB, Huang Z, Fuente A, Soranzo N, Settlage RE, Chuang CC, Howard T, Xu N, Goodarzi MO, Ida Chen YD, Rotter JI, Siscovick DS, Parks JS, Murphy S, Jacobs DR, Jr., Post W, Tracy RP, Wild PS, Blankenberg S, Hoeschele I, Herrington D, McCall CE, Liu Y.  Alterations of a cellular cholesterol metabolism network is a molecular feature of obesity-related type 2 diabetes and cardiovascular disease. Diabetes, 2015.
• Wendelboe AM, McCumber M, Hylek EM, Buller H, Weitz JI, Raskob G, Day ISCfWT. 2015. Global public awareness of venous thromboembolism. Journal of thrombosis and haemostasis : JTH 13:1365-1371, 2015.
• Gori T, Wild PS, Schnabel R, Schulz A, Pfeiffer N, Blettner M, Beutel ME, Forconi S, Jung F, Lackner KJ, Blankenberg S, Münzel T. The distribution of whole blood viscosity, its determinants and relationship with arterial blood pressure in the community: cross-sectional analysis from the Gutenberg Health Study. Therapeutic advances in cardiovascular disease, 2015.
• Demircik F, Ramljak S, Hermanns I, Pfützner A, Pfützner A. Evaluation of hematocrit interference with MyStar extra and seven competitive devices. Journal of diabetes science and technology. 9:262-267, 2015.
• Jabs A, Oelze M, Mikhed Y, Stamm P, Kröller-Schön S, Welschof P, Jansen T, Hausding M, Kopp M, Steven S, Schulz E, Stasch JP, Münzel T, Daiber A. Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats. Vascular pharmacology, 2015.
• Steven S, Hausding M, Kröller-Schön S, Mader M, Mikhed Y, Stamm P, Zinssius E, Pfeffer A, Welschof P, Agdauletova S, Sudowe S, Li H, Oelze M, Schulz E, Klein T, Münzel T, Daiber A. Gliptin and GLP-1 analog treatment improves survival and vascular inflammation/dysfunction in animals with lipopolysaccharide-induced endotoxemia. Basic research in cardiology. 110:6, 2015.
• Horke S, Xiao J, Schutz EM, Kramer GL, Wilgenbus P, Witte I, Selbach M, Teiber JF. A novel paraoxonase 2-dependent mechanism mediating the biological effects of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone. Infection and immunity, 2015.
• Hermanns MI, Grossmann V, Spronk HM, Schulz A, Junger C, Laubert-Reh D, Mazur J, Gori T, Zeller T, Pfeiffer N, Beutel M, Blankenberg S, Münzel T, Lackner KJ, Ten Cate-Hoek AJ, Ten Cate H, Wild PS. Distribution, genetic and cardiovascular determinants of FVIII:c - Data from the population-based Gutenberg Health Study. International journal of cardiology. 187:166-174, 2015.
• Krüger M, Pabst AM, Al-Nawas B, Horke S, Moergel M. Paraoxonase-2 (PON2) protects oral squamous cell cancer cells against irradiation-induced apoptosis. Journal of cancer research and clinical oncology, 2015.
• Hinkel R, Lange P, Petersen B, Gottlieb E, Ng JK, Finger S, Horstkotte J, Lee S, Thormann M, Knorr M, El-Aouni C, Boekstegers P, Reichart B, Wenzel P, Niemann H, Kupatt C. Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation: An Experimental Study in a Pre-Clinical Pig Model. Journal of the American College of Cardiology. 66:154-165, 2015.
• von Krogh AS, Kremer Hovinga JA, Romundstad PR, Roten LT, Lämmle B, Waage A, Quist-Paulsen P. ADAMTS13 gene variants and function in women with preeclampsia: A population- based nested case- control study from the HUNT Study. Thrombosis research, 14: 73-82. 2015.
• Raum P, Lamparter J, Ponto KA, Peto T, Hoehn R, Schulz A, Schneider A, Wild PS, Pfeiffer N, Mirshahi A. Prevalence and Cardiovascular Associations of Diabetic Retinopathy and Maculopathy: Results from the Gutenberg Health Study. PloS one. 10:e0127188, 2015.
  • Correction

• Gogiraju R, Xu X, Bochenek ML, Steinbrecher JH, Lehnart SE, Wenzel P, Kessel M, Zeisberg EM, Dobbelstein M, Schäfer K. Endothelial p53 deletion improves angiogenesis and prevents cardiac fibrosis and heart failure induced by pressure overload in mice. Journal of the American Heart Association 4, 2015.
• Frank B, Ariza L, Lamparter H, Grossmann V, Prochaska JH, Ullmann A, Kindler F, Weisser G, Walter U, Lackner KJ, Espinola-Klein C, Munzel T, Konstantinides SV, Wild PS, group VTs. Rationale and design of three observational, prospective cohort studies including biobanking to evaluate and improve diagnostics, management strategies and risk stratification in venous thromboembolism: the VTEval Project. BMJ open 5:e008157, 2015.
• Klok FA, Niemann C, Dellas C, Hasenfuss G, Konstantinides S, Lankeit M. Performance of five different bleeding-prediction scores in patients with acute pulmonary embolism. Journal of thrombosis and thrombolysis, 2015.
• Stakos DA, Kambas K, Konstantinidis T, Mitroulis I, Apostolidou E, Arelaki S, Tsironidou V, Giatromanolaki A, Skendros P, Konstantinides S, Ritis K. Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction. European heart journal 36:1405-1414, 2015.
• Ponto KA, Elbaz H, Peto T, Laubert-Reh D, Binder H, Wild PS, Lackner K, Pfeiffer N, Mirshahi A. Prevalence and risk factors of retinal vein occlusion: the Gutenberg Health Study.  J Thromb Haemost. 13:1254-1263, 2015.
• Grossmann V, Schmitt VH, Zeller T, Panova-Noeva M, Schulz A, Laubert-Reh D, Juenger C, Schnabel RB, Abt TG, Laskowski R, Wiltink J, Schulz E, Blankenberg S, Lackner KJ, Münzel T, Wild PS. Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes. Diabetis care. pii: dc143008, 2015.
• Russkamp NF, Ruemmler R, Roewe J, Moore BB, Ward PA, Bosmann M. Experimental design of complement component 5a-induced acute lung injury (C5a-ALI): a role of CC-chemokine receptor type 5 during immune activation by anaphylatoxin. FASEB journal pii: fj.15-271635, 2015.
• Bollmann F*, Jäckel S*, Schmidtke L, Schrick K, Reinhardt C, Jurk K, Wu Z, Xia N, Li H, Erkel G, Walter U, Kleinert H**, Pautz A**. Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice. PloS one. 10:e0130401, 2015.
• Müller-Calleja N, Kohler A, Siebald B, Canisius A, Orning C, Radsak M, Stein P, Monnikes R, Lackner KJ. Cofactor-independent antiphospholipid antibodies activate the NLRP3-inflammasome via endosomal NADPH-oxidase: implications for the antiphospholipid syndrome. Thrombosis and haemostasis 113, 2015.
• Michal M, Prochaska JH, Keller K, Göbel S, Coldewey M, Ullmann A, Schulz A, Lamparter H, Münzel T, Reiner I, Beutel ME, Wild PS. Symptoms of depression and anxiety predict mortality in patients undergoing oral anticoagulation: Results from the thrombEVAL study program. International journal of cardiology 187:614-619, 2015.
• Zolfaghari S, Harenberg J, Frölich L, Weiss C, Wehling M, Wild P, Prochaska J, Beyer-Westendorf J, Koscielny J, Lip GY. Development of recommendations to continue anticoagulation with one of the two types of oral anticoagulants based on the identification of patients' preference. Seminars in thrombosis and hemostasis 41:166-177, 2015.
• Wu Z, Siuda D, Xia N, Reifenberg G, Daiber A, Münzel T, Förstermann U, Li H. Maternal treatment of spontaneously hypertensive rats with pentaerythritol tetranitrate reduces blood pressure in female offspring. Hypertension. 65:232-237, 2015.
  • DZHK-Paper of the month: Januar 2015
  • DZHK Pressemitteilung

• Taddonio MA, Dolgachev V, Bosmann M, Ward PA, Su G, Wang SC, Hemmila MR. Influence of Lipopolysaccharide Binding Protein on Pulmonary Inflammation in Gram-negative Pneumonia. Shock. 2015.
• Kalbitz M, Grailer JJ, Fattahi F, Jajou L, Herron TJ, Campbell KF, Zetoune FS, Bosmann M, Sarma JV, Huber-Lang M, Gebhard F, Loaiza R, Valdivia HH, Jalife J, Russell MW, Ward PA. Role of extracellular histones in the cardiomyopathy of sepsis. FASEB journal. pii: fj.14-268730, 2015.
• Henninger C, Huelsenbeck S, Wenzel P, Brand M, Huelsenbeck J, Schad A, Fritz G. Chronic heart damage following doxorubicin treatment is alleviated by lovastatin. Pharmacological research. 91:47-56, 2015.
• Prochaska JH, Gobel S, Keller K, Coldewey M, Ullmann A, Lamparter H, Junger C, Al-Bayati Z, Baer C, Walter U, Bickel C, Ten Cate H, Munzel T, Wild PS. Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service inverted question mark results from the prospective, multi-center, observational cohort study thrombEVAL. BMC medicine. 13:14, 2015.
• Kaeberich A, Seeber V, Jimenez D, Kostrubiec M, Dellas C, Hasenfuss G, Giannitsis E, Pruszczyk P, Konstantinides S, Lankeit M. Age-adjusted hsTnT cut-off value for risk stratification of pulmonary embolism. The European respiratory journal. 2015.
• Kurmann R, Weisstanner C, Kardas P, Hirsch HH, Wiest R, Lämmle B, Furrer H, Du Pasquier R, Bassetti CL, Sturzenegger M, Krestel H. Progressive multifocal leukoencephalopathy in common variable immunodeficiency: mitigated course under mirtazapine and mefloquine. Journal of neurovirology, 21: 694-701. 2015.
• von Känel R, Margani A, Stauber S, Meyer FA, Demarmels Biasiutti F, Vökt F, Wissmann T, Lämmle B, Lukas PS. Depressive symptoms as a novel risk factor for recurrent venous thromboembolism: a longitudinal observational study in patients referred for thrombophilia investigation. PloS one 10:e0125858, 2015.
• Brandao I, Hörmann N, Jäckel S, Reinhardt C. TLR5 expression in the small intestine depends on the adaptors MyD88 and TRIF, but is independent of the enteric microbiota. Gut microbes:1-5, 2015.
• Schnabel RB, Johannsen SS, Wild PS, Blankenberg S. [Prevalence and risk factors of atrial fibrillation in Germany : data from the Gutenberg Health Study]. Herz 40:8-15, 2015.
• Rothmeier AS, Marchese P, Petrich BG, Furlan-Freguia C, Ginsberg MH, Ruggeri ZM, Ruf W. Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. The Journal of clinical investigation. 125:1471-1484, 2015.
• Klok FA, Tesche C, Rappold L, Dellas C, Hasenfuss G, Huisman MV, Konstantinides S, Lankeit M. External validation of a simple non-invasive algorithm to rule out chronic thromboembolic pulmonary hypertension after acute pulmonary embolism. Thrombosis research 135:796-801, 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Modified Bova score for risk stratification and short-term outcome in acute pulmonary embolism. The Netherlands journal of medicine 73:410-416. 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Blood pressure for outcome prediction and risk stratification in acute pulmonary embolism. The American journal of emergency medicine 33:1617-1621. 2015.
• Keller K, Beule J, Coldewey M, Geyer M, Balzer JO, Dippold W. The risk factor age in normotensive patients with pulmonary embolism: Effectiveness of age in predicting submassive pulmonary embolism, cardiac injury, right ventricular dysfunction and elevated systolic pulmonary artery pressure in normotensive pulmonary embolism patients. Experimental gerontology 69:116-121. 2015.
• Keller K, Beule J, Balzer JO, Dippold W. Typical symptoms for prediction of outcome and risk stratification in acute pulmonary embolism. International angiology. 2015.
• Keller K, Beule J, Schulz A, Coldewey M, Dippold W, Balzer JO. D-dimer for risk stratification in haemodynamically stable patients with acute pulmonary embolism. Advances in medical sciences 60:204-210. 2015.
• Keller K, Beule J, Coldewey M, Dippold W, Balzer JO. Heart rate in pulmonary embolism. Internal and emergency medicine 10:663-669. 2015.
• Keller K, Geyer M, Beule J, Coldewey M, Balzer JO, Dippold W. Impact of cancer on the effectiveness of cardiac Troponin I to predict right ventricular dysfunction in acute pulmonary embolism. Thoracic cancer 6:584-588. 2015.
• Keller K, Beule J, Coldewey M, Dippold W, Balzer JO. Impact of advanced age on the severity of normotensive pulmonary embolism. Heart and vessels 30:647-656. 2015.
• Keller K, Beule J, Schulz A, Coldewey M, Dippold W, Balzer JO. Cardiac troponin I for predicting right ventricular dysfunction and intermediate risk in patients with normotensive pulmonary embolism. Netherlands heart journal 23:55-61. 2015.

Reviews 2015

• Hahn SA, Bellinghausen I, Trinschek B, Becker C. Translating Treg Therapy in Humanized Mice. Frontiers in immunology 6:623. 2015.
• Daiber A, Di Lisa F, Oelze M, Kröller-Schön S, Steven S, Schulz E, Münzel T. Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function. British journal of pharmacology. 2015.
• van der Meijden PE, Ozaki Y, Ruf W, de Laat B, Mutch N, Diamond S, Nieuwland R, Peters TC, Heestermans M, Kremers RM, Moorlag M, Boender J, Unlu B, Reitsma PH. Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome). Thrombosis research. 136 Suppl 1:S3-7. 2015.
• Comerota AJ, Sandset PM, Konstantinides S, de Graaf R, Wakefield TW, Arnoldussen CW, Lam YL, van Gent WB, de Wolf MA, Catarinella FS, Kurstjens RL, Alshabatat A, Wittens CH. Theme 4: Invasive management of (recurrent) VTE and PTS. Thrombosis research 136 Suppl 1:S19-25. 2015.
• Konstantinides S. [Coronary heart disease: Genetic score identifies risk patients]. Deutsche medizinische Wochenschrift 140:1418.
• Hellenkamp K, Schwung J, Rossmann H, Kaeberich A, Wachter R, Hasenfuss G, Konstantinides S, Lankeit M. Risk stratification of normotensive pulmonary embolism: prognostic impact of copeptin. The European respiratory journal. 2015.
• Grove EL, Lankeit M, Hess K, Freynhofer M, Stojkovic S, Varenhorst C, Thomas M. CardioPulse: the 'Young Thrombosis Researchers Group' of the ESC Working Group on Thrombosis. European heart journal. 36:703-704, 2015.
• Steven S, Münzel T, Daiber A. Exploiting the Pleiotropic Antioxidant Effects of Established Drugs in Cardiovascular Disease. International journal of molecular sciences. 16:18185-18223, 2015.
• Ruf W. Diverse packaging of TF into platelets. Thrombosis and haemostasis. 114, 2015.
• Mikhed Y, Daiber A, Steven S. Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction. International journal of molecular sciences. 16:15918-15953, 2015.
• Wärntges S, Konstantinides SV. Progress in the management of acute pulmonary embolism. Current opinion in pulmonary medicine, 2015.
• Klok FA, Meyer G, Konstantinides S. Management of intermediate-risk pulmonary embolism: uncertainties and challenges. http://www.ncbi.nlm.nih.gov/pubmed/26109174European journal of haematology, 2015.
• Konstantinides SV, Wärntges S. Acute phase treatment of venous thromboembolism: advanced therapy. Systemic fibrinolysis and pharmacomechanical therapy. Thrombosis and haemostasis 113, 2015.
• Ruf W, Samad F. Tissue factor pathways linking obesity and inflammation. Hamostaseologie 35, 2015.
• Klok FA, Kooiman J, Huisman MV, Konstantinides S, Lankeit M. Predicting anticoagulant-related bleeding in patients with venous thromboembolism: a clinically oriented review. The European respiratory journal. 45:201-210, 2015.
• Lämmle B. VWF and complement. Blood. 125:896-898, 2015.
• von Auer C, von Krogh AS, Kremer Hovinga JA, Lämmle B. Current insights into thrombotic microangiopathies: Thrombotic thrombocytopenic purpura and pregnancy. Thrombosis research 135 Suppl 1:S30-33, 2015.
• Kruger P, Saffarzadeh M, Weber AN, Rieber N, Radsak M, von Bernuth H, Benarafa C, Roos D, Skokowa J, Hartl D. Neutrophils: Between host defence, immune modulation, and tissue injury. PLoS pathogens 11:e1004651, 2015.
• Keller K, Engelhardt M. [Historical Changes in Meniscus Surgery--The Changing Appreciation of Disease, Surgical Techniques and Complications]. Zeitschrift fur Orthopadie und Unfallchirurgie 153:259-266. 2015.

Editorials und Fachbeiträge 2015

• Konstantinides SV, Lankeit M, Wild P, Quitzau K, Binder H, im Auftrag der F-I. [Follow-up after acute pulmonary embolism. A prospective non-interventional multi-center cohort study (FOCUS)]. Deutsche medizinische Wochenschrift. 140 Suppl 1:S20-21, 2015.

Originalartikel 2014

• Bosmann M, Russkamp NF, Strobl B, Roewe J, Balouzian L, Pache F, Radsak MP, van Rooijen N, Zetoune FS, Sarma JV, Nunez G, Muller M, Murray PJ, Ward PA. Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3. Journal of immunology. 193:5668-5677, 2014.
• Oelze M, Kroller-Schon S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Munzel T, Daiber A. Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging. Hypertension. 63:390-396, 2014.
• Zeller T, Ojeda F, Brunner FJ, Peitsmeyer P, Munzel T, Binder H, Pfeiffer N, Michal M, Wild PS, Blankenberg S, Lackner KJ. High-sensitivity cardiac troponin I in the general population - defining reference populations for the determination of the 99th percentile in the Gutenberg Health Study. Clinical chemistry and laboratory medicine. 2014.
• Wiltink J, Michal M, Wild PS, Schneider A, Konig J, Blettner M, Munzel T, Schulz A, Weber M, Fottner C, Pfeiffer N, Lackner K, Beutel ME. Associations between depression and diabetes in the community: do symptom dimensions matter? Results from the Gutenberg Health Study. PloS one 9:e105499, 2014.
• Schnabel RB, Wild PS, Wilde S, Ojeda FM, Schulz A, Zeller T, Sinning CR, Kunde J, Lackner KJ, Munzel T, Blankenberg S. Multiple biomarkers and atrial fibrillation in the general population. PloS one. 9:e11248, 2014.
• Michal M, Wiltink J, Kirschner Y, Schneider A, Wild PS, Munzel T, Blettner M, Schulz A, Lackner K, Pfeiffer N, Blankenberg S, Tschan R, Tuin I, Beutel ME. Complaints of sleep disturbances are associated with cardiovascular disease: results from the Gutenberg Health Study. PloS one. 9:e104324, 2014.
• Michal M, Prochaska JH, Ullmann A, Keller K, Gobel S, Coldewey M, Munzel T, Wiltink J, Beutel ME, Wild PS. Relevance of depression for anticoagulation management in a routine medical care setting: Results from the ThrombEVAL study program. Journal of thrombosis and haemostasis. 2014.
• Luneburg N, Lieb W, […], Wild PS, […], Vasan RS, Boger RH. Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine. Circulation. Cardiovascular genetics. 2014.
• Karbach S, Croxford AL, Oelze M, Schuler R, Minwegen D, Wegner J, Koukes L, Yogev N, Nikolaev A, Reissig S, Ullmann A, Knorr M, Waldner M, Neurath MF, Li H, Wu Z, Brochhausen C, Scheller J, Rose-John S, Piotrowski C, Bechmann I, Radsak M, Wild P, Daiber A, von Stebut E, Wenzel P, Waisman A, Munzel T. Interleukin 17 drives vascular inflammation, endothelial dysfunction, and arterial hypertension in psoriasis-like skin disease. Arteriosclerosis, thrombosis, and vascular biology. 34:2658-2668, 2014.
• Engelhardt B, Konig J, Blettner M, Wild P, Munzel T, Lackner K, Blankenberg S, Pfeiffer N, Beutel M, Zwiener I. 2014. Combining cross-sectional data on prevalence with risk estimates from a prediction model. A novel method for estimating the attributable risk. Methods of information in medicine. 53:371-379, 2014.
• Beygui F, Wild PS, Zeller T, Germain M, Castagne R, Lackner KJ, Munzel T, Montalescot G, Mitchell GF, Verwoert GC, Tarasov KV, Tregouet DA, Cambien F, Blankenberg S, Tiret L. Adrenomedullin and arterial stiffness: integrative approach combining monocyte ADM expression, plasma MR-Pro-ADM, and genome-wide association study. Circulation. Cardiovascular genetics. 7:634-641, 2014.
• Hörmann N, Brandao I, Jäckel S, Ens N, Lillich M, Walter U, Reinhardt C. Gut microbial colonization orchestrates TLR2 expression, signaling and epithelial proliferation in the small intestinal mucosa. PloS one. 9:e113080, 2014.
• Kossmann S, Hu H, Steven S, Schönfelder T, Fraccarollo D, Mikhed Y, Brähler M, Knorr M, Brandt M, Karbach SH, Becker C, Oelze M, Bauersachs J, Widder J, Münzel T, Daiber A, Wenzel P. Inflammatory Monocytes Determine Endothelial Nitric Oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II. Journal of Biological Chemistry. pii: jbc.M114.604231, 2014.
• Zeller T, Keller T, Ojeda F, Reichlin T, Twerenbold R, Tzikas S, Wild PS, Reiter M, Czyz E, Lackner KJ, Munzel T, Mueller C, Blankenberg S. Assessment of microRNAs in patients with unstable angina pectoris. European Heart Journal. 35(31):2106-14, 2014.
• Weber M, Rudolph B, Stein P, Yogev N, Bosmann M, Schild H, Radsak MP. Host-derived CD8+ dendritic cells protect against acute Graft-versus-Host Disease after experimental allogeneic bone marrow transplantation. Biology of Blood and Marrow Transplantation. pii: S1083-8791(14)00504-7, 2014.
• Dorweiler B, Grechowa I, Wallrath A, Vahl CF, Horke S. Activation of the pro-apoptotic unfolded protein response in plaques of the human carotid artery. European Journal of Vascular and Endovascular Surgery. pii: S1078-5884(14)00357-8, 2014. 
• Ponto KA, Zwiener I, Al-Nawas B, Kahaly GJ, Otto AF, Karbach J. Piezosurgery for Orbital Decompression Surgery in Thyroid Associated Orbitopathy. Journal of Cranio-Maxillofacial Surgery. pii: S1010-5182(14)00204-2, 2014. 
• Hubertus K, Mischnik M, Timmer J, Herterich S, Mark R, Moulard M, Walter U, Geiger J. Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors. European Journal of Pharmacology. 740C:15-27, 2014. 
• de Witt SM, Swieringa F, Cavill R, ... Jurk K ... Heemskerk JW, Cosemans JM. Identification of platelet function defects by multi-parameter assessment of thrombus formation. Nature Communications. 5:4257, 2014.
• Herder C, Nuotio ML, Shah S, Blankenberg S, ..., Wild PS, ... Kumari M, Perola M, Salomaa V. Genetic determinants of circulating interleukin-1 receptor antagonist levels and their association with glycemic traits. Diabetes.  pii: DB_140731, 2014.
• Knorr M, Hausding M, Pfeffer A, Jurk K, Jansen T, Schwierczek K, Oelze M, Kröller-Schön S, Schulz E, Wenzel P, Gori T, Burgin K, Sartor D, Scherhag A, Münzel T, Daiber A. In vitro and in vivo Characterization of a New Organic Nitrate Hybrid Drug Covalently Bound to Pioglitazone. Pharmacology. 93(5-6):203-215, 2014. 
• Oelze M, Kröller-Schön S, Steven S, Lubos E, Doppler C, Hausding M, Tobias S, Brochhausen C, Li H, Torzewski M, Wenzel P, Bachschmid M, Lackner KJ, Schulz E, Münzel T, Daiber A. Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging. Hypertension. 63(2):390-6, 2014.
• Prüfer S, Weber M, Stein P, Bosmann M, Stassen M, Kreft A, Schild H, Radsak MP. Oxidative burst and neutrophil elastase contribute to clearance of Aspergillus fumigatus pneumonia in mice. Immunobiology. 219:87-96, 2014.
• Ostad MA, Wild PS, Schnorbus B, Schulz A, Munzel T, Warnholtz A. Predictive value of brachial reactive hyperemia and flow-mediated dilation in stable coronary artery disease. Clinical Hemorheology and Microcirculation. 56(3):247-57, 2014.
• Bollmann F, Wu Z, Oelze M, Siuda D, Xia N, Henke J, Daiber A, Li H, Stumpo DJ, Blackshear PJ, Kleinert H, Pautz A. Endothelial Dysfunction in Tristetraprolin-deficient Mice Is Not Caused by Enhanced Tumor Necrosis Factor-α Expression. The Journal of Biological Chemistry. Vol. 289, No. 22, pp. 15653–15665, 2014.
• Schnorbus B, Daiber A, Jurk K, Warnke S, König J, Krahn U, Lackner K, Munzel T, Gori T. Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patients undergoing coronary artery stenting for an acute coronary syndrome. A randomised, prospective, controlled study. BMJ open. 4(5):e005268, 2014. 
• von Krogh AS, Kremer Hovinga JA, Tjønnfjord GE, Ringen IM, Lämmle B, Waage A, Quist-Paulsen P. The impact of congenital thrombotic thrombocytopenic purpura on pregnancy complications. Thrombosis and Haemostasis. 111(6):1180-3, 2014.
• Ponto K, Schuppan D, Zwiener I, Binder H, Mirshahi A, Diana T, Pitz S, Pfeiffer N, Kahaly G. Thyroid-associated orbitopathy is linked to gastrointestinal autoimmunity. Clinical and experimental immunology. 2014.
• Beutel ME, Wiltink J, Kirschner Y, Sinning C, Espinola-Klein C, Wild PS, Munzel T, Blettner M, Zwiener I, Lackner K, Michal M. History of depression but not current depression is associated with signs of atherosclerosis: data from the Gutenberg Health Study. Psychological Medicine. 44(5):919-25, 2014. 
• Prochaska JH, Coldewey M, Göbel S, Keller K, Hendelmeier M, Konstantinides S, Münzel T, Wild PS; for the thrombEVAL Study Group. Evaluation of oral anticoagulation therapy: rationale and design of the thrombEVAL study programme. European journal of preventive cardiology. 2014.
• Bova C, Sanchez O, Prandoni P, Lankeit M, Konstantinides S, Vanni S, Jiménez D. Identification of intermediate-risk patients with acute symptomatic pulmonary embolism. European Respiratory Journal. 2014.
• Meyer G, Vicaut E, ... Lankeit M, ... Torbicki A, Verschuren F, and Konstantinides SV for the PEITHO Investigators. Fibrinolysis for Patients with Acute Intermediate-Risk Pulmonary Embolism. New England Journal of Medicine. 370:1402-11, 2014. 
• Dellas C, Tschepe M, Seeber V, Zwiener I, Kuhnert K, Schäfer K, Hasenfuß G, Konstantinides S, Lankeit M. A novel H-FABP assay and a fast prognostic score for risk assessment of normotensive pulmonary embolism. Thrombosis Haemostasis. 111(5):996-1003, 2014. 
• Navdaev A, Subramanian H, Petunin A, Clemetson KJ, Gambaryan S, Walter U. Echicetin Coated Polystyrene Beads: A Novel Tool to Investigate GPIb-Specific Platelet Activation and Aggregation. PLOS One. 9(4):e93569, 2014.
• Jiang Y, McIntosh JJ, Reese JA, Deford CC, Kremer Hovinga JA, Lämmle B, Terrell DR, Vesely SK, Knudtson EJ, George JN. Pregnancy outcomes following recovery from acquired thrombotic thrombocytopenic purpura. Blood 123(11):1674-80, 2014. 
• Lankeit M, Jiménez D, Kostrubiec M, Dellas C, Kuhnert K, Hasenfuß G, Pruszczyk P, Konstantinides S. Validation of N-terminal pro-brain natriuretic peptide cut-off values for risk stratification of pulmonary embolism. European Respiratory Journal. 43(6):1669-77, 2014.
• Jiménez D, Kopecna D, Tapson V, Briese B, Schreiber D, Lobo JL, Monreal M, Aujesky D, Sanchez O, Meyer G, Konstantinides S, Yusen RD. Derivation and validation of multimarker prognostication for normotensive patients with acute symptomatic pulmonary embolism. American Journal of Respiratory and Critical Care Medicine. 189(6):718-26, 2014. 
• Bosmann M, Strobl B, Kichler N, Rigler D, Grailer JJ, Pache F, Murray PJ, Müller M, Ward PA. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27. Journal of Leukocyte Biology. 96(1):123-31, 2014.
• Sinning C, Keller T, Zeller T, Ojeda F, Schlüter M, Schnabel R, Lubos E, Bickel C, Lackner KJ, Diemert P, Munzel T, Blankenberg S, Wild PS. Association of high-sensitivity assayed troponin I with cardiovascular phenotypes in the general population: the population-based Gutenberg health study. Clinical Research in Cardiology. 103(3):211-22, 2014.
• Anaraki P, Patecki M, Larmann J, Tkachuk S, Jurk K, Haller H, Theilmeier G, Dumler I. Urokinase Receptor Mediates Osteogenic Differentiation of Mesenchymal Stem Cells and Vascular Calcification via the Complement C5a Receptor. Stem Cells and Development. 15;23(4):352-62, 2014. 
• Brandt M, Schönfelder T, Schwenk M, Becker C, Jäckel S, Reinhardt C, Stark K, Massberg S, Münzel T, von Brühl ML, Wenzel P. Deep vein thrombus formation induced by flow reduction in mice is determined by venous side branches. Clinical Hemorheology and Microcirculation. 56(2):145-52, 2014. 
• Beck F, Geiger J, Gambaryan S, Veit J, Vaudel M, Nollau P, Kohlbacher O, Martens L, Walter U, Sickmann A, Zahedi RP. Time-resolved characterization of camp/pka-dependant signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways. Blood. 123(5):e1-e10, 2014. 
• Kröller-Schön S, Steven S, Kossmann S, Scholz A, Daub S, Oelze M, Xia N, Hausding M, Mikhed Y, Zinßius E, Mader M, Stamm P, Treiber N, Scharffetter-Kochanek K, Li H, Schulz E, Wenzel P, Münzel T, Daiber A. Molecular Mechanisms of the Crosstalk Between Mitochondria and NADPH Oxidase Through Reactive Oxygen Species-Studies in White Blood Cells and in Animal Models. Antioxidants & Redox Signaling. 20(2):247-66, 2014. 
• Zwiener I, Frisch B, Binder H. Transforming RNA-Seq Data to Improve the Performance. PLOS ONE.  9(1): e85150, 2014. 
• Rocanin-Arjo A, Cohen W, ... Wild PS, ... Trégouët DA, Morange PE. A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential. Blood. 123(5):777-85, 2014.
• Prüfer S, Weber M, Sasca D, Teschner D, Wölfel C, Stein P, Stassen M, Schild H, Radsak MP. Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells. Journal Innate Immunology. 6(3): 339-352, 2014. 
• Jimenez-Alcazar M, Napirei M, Panda R, Kohler EC, Kremer-Hovinga JA, Mannherz HG, Peine S, Renne T, Lämmle B, Fuchs TA. Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies. Journal of thrombosis and haemostasis, 13: 732-42. 2014.
• Stroka D, Keogh A, Vu D, Fort A, Stoffel MH, Kuhni-Boghenbor K, Furer C, Banz V, Demarmels Biasiutti F, Lämmle B, Candinas D, Neerman-Arbez M. In vitro rescue of FGA deletion by lentiviral transduction of an afibrinogenemic patient's hepatocytes. Journal of thrombosis and haemostasis, 12: 1874-9. 2014.

Reviews 2014

• Schönfelder T, Jäckel S, Wenzel P. Mouse models of deep vein thrombosis. Gefässchirurgie. 19:257–262, 2014.
• Knorr M, Münzel T, Wenzel P. Interplay of NK cells and monocytes in vascular inflammation and myocardial infarction. Frontiers in physiology. 5:295, 2014.
• Konstantinides SV, Torbicki A. Management of pulmonary embolism: recent evidence and the new European guidelines. The European respiratory journal. 44:1385-1390, 2014.
• Konstantinides S, Torbicki A. Management of venous thrombo-embolism: an update. European heart journal, 2014.
• Klok FA, van der Hulle T, den Exter PL, Lankeit M, Huisman MV, Konstantinides S. The post-PE syndrome: a new concept for chronic complications of pulmonary embolism. Blood reviews. 2014.
• Kaberich A, Warntges S, Konstantinides S. Risk-adapted management of acute pulmonary embolism: recent evidence, new guidelines. Rambam Maimonides medical journal. 5:e0040, 2014.
• Raskob GE, Angchaisuksiri P, Blanco AN, Büller H, Gallus A, Hunt BJ, Hylek EM, Kakkar TL, Konstantinides SV, McCumber M, Ozaki Y, Wendelboe A, Weitz JI. Thrombosis: a major contributor to global disease burden. Thrombosis and haemostasis. 112:843-852, 2014.
• Clemens A, Strack A, Noack H, Konstantinides S, Brueckmann M, Lip GY. Anticoagulant-related gastrointestinal bleeding--could this facilitate early detection of benign or malignant gastrointestinal lesions? Annals of medicine. 46:672-678, 2014.
• Lammle B, Walter U. Pearls, guidelines & more. Hamostaseologie. 34:199, 2014.
• Ruf W, Schaffner F. Role of the protein C receptor in cancer progression. Thromb Res. 133 Suppl 2:S85-9, 2014.
• Wilkens H, Lang I, Blankenburg T, Grohé C, Guth S, Held M, Klepetko W, Konstantinides S, Kramm T, Krüger U, Lankeit M, Schäfers HJ, Seyfarth HJ, Mayer E. Chronic thromboembolic pulmonary hypertension - A position paper. Deutsche Medizinische Wochenschrift. 2014 Aug 1. [Epub ahead of print] (P1C)
• Marti C, John G, Konstantinides S, Combescure C, Sanchez O, Lankeit M, Meyer G, Perrier A. Systemic thrombolytic therapy for acute pulmonary embolism: a systematic review and meta-analysis. European Heart Journal. 2014 Jun 10. pii: ehu218.
• Lankeit M, Konstantinides S; Aktuelle Therapie und Sekundärprävention der Lungenembolie; Gefässchirurgie - Zeitschrift für vaskuläre und endovaskuläre Medizin; 2014; 19: 77–90. CME-zertifizierte Fortbildung 
• Lankeit M, Konstantinides S. Thrombolyse bei akuter Lungenembolie – Risikostratifizierung, risikoadaptierte Diagnostik und Therapie. Klinikarzt. 2014. 433 (S1): 6-11. CME-zertifizierte Fortbildung 
• Klok FA, Kooiman J, Huisman MV, Konstantinides S, Lankeit M. Predicting anticoagulant-related bleeding in patients with venous thromboembolism: a clinically oriented review. European Respiratory Journal. 2014 
• Karbach S, Wenzel P, Waisman A, Munzel T, Daiber A. eNOS Uncoupling in Cardiovascular Diseases - the Role of Oxidative Stress and Inflammation. Current Pharmaceutical Design. 2014. 20(22):3579-94 
• Burkhart JM, Gambaryan S, Watson SP, Jurk K, Walter U, Sickmann A, Heemskerk JWM, Zahedi RP. What Can Proteomics Tell Us About Platelets?. Circulation Research 2014; 114:1204-1219
• Bosmann M, Ward PA. Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps. Expert Opinion on Therapeutic Targets 2014; 2014 Jun;18(6):703-14
• Keller K, Beule J, Oliver Balzer J, Coldewey M, Munzel T, Dippold W, Wild P. A 56-year-old man with co-prevalence of Leriche syndrome and dilated cardiomyopathy: case report and review. Wiener Klinische Wochenschrift. 2014 Mar;126(5-6):163-8
• Schulz E, Wenzel P, Munzel T, Daiber A. Mitochondrial Redox Signaling: Interaction of Mitochondrial Reactive Oxygen Species with Other Sources of Oxidative Stress. Antioxid Redox Signal 2014 Jan 10; 20(2):308-24
• Langer F, Ruf W. Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation. Thrombosis Haemostasis 2014 Jan 23;111(3)
• Lutz J, Menke J, Sollinger D, Schinzel H, Thürmel K. Haemostasis in chronic kidney disease. Nephrology Dialysis Transplantation. 2014 Jan;29(1):29-40
• Schinzel H, Weilemann LS. Monitoring of anticoagulation-management in practice. Deutsche Medizinische Wochenschrift. 2014 Jan;139 Suppl 1:S27-30
• Jurk K. Analysis of platelet function and dysfunction. Hamostaseologie. 35, 2014.

Editorials und Fachbeiträge 2014

• Konstantinides SV, Torbicki A, Agnelli G, Danchin N, Fitzmaurice D, Galie N, Gibbs JS, Huisman MV, Humbert M, Kucher N, Lang I, Lankeit M, Lekakis J, Maack C, Mayer E, Meneveau N, Perrier A, Pruszczyk P, Rasmussen LH, Schindler TH, Svitil P, Vonk Noordegraaf A, Zamorano JL, Zompatori M, Task Force for the D, Management of Acute Pulmonary Embolism of the European Society of C. 2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. European heart journal. 35:3033-3069, 3069a-3069k, 2014.
  • Corrigiendum

• Beyer-Westendorf J, Konstantinides S, Kucher N. Akute Lungenembolie. In Mayet W-J, Mertens PR, Meyer J, Müller OA, Pfeifer M, Pletz MW, Schellinger P, Weiss N, Wendtner CM (Editors). Rationelle Diagnostik und Therapie in der Inneren Medizin. Elsevier, Urban & Fischer, 2014, ISBN 978-3-437-22838-4
• Colucci G, Alberio L, Demarmels Biasiutti F, Lämmle B. Bilateral periorbital ecchymoses. An often missed sign of amyloid purpura. Hamostaseologie. 2014 Aug 5;34(3):249-52. 
• Hecking C, Hendelmeier M, von Bardeleben R, Gröschel K, Schinzel H. Recurrent cerebral ischaemia in a pregnant woman with patent foramen ovale II° and thrombophilia. Hamostaseologie 2014 Jun 30;34(3)
• Beck O, Martin C, Alt F, Wingerter A, Staatz G, Schinzel H, Faber J. Massive pulmonary embolism in a young boy with T-cell leukaemia. Successful thrombolytic therapy by recombinant tissue plasminogen activator (rtPA). Hamostaseologie 2014 Jun 30;34(3)
• Falter T, Kremer Hovinga JA, Lackner K, Füllemann HG, Lämmle B, Scharrer I. Late onset and pregnancy-induced congenital thrombotic thrombocytopenic purpura. Hamostaseologie 2014 Jul 4;34(3) 
• Konstantinides SV. Asthma and pulmonary embolism: bringing airways and vessels closer together. European Respiratory Journal 2014 Mar;43(3):694-6
• Lankeit M, Konstantinides S. Aktuelle Therapie und Sekundärprävention der Lungenembolie. Gefässchirurgie - Zeitschrift für vaskuläre und endovaskuläre Medizin 2014; 19: 77–90

Originalartikel 2013

• Bosmann M, Grailer JJ, Ruemmler R, Russkamp NF, Zetoune FS, Sarma JV, Standiford TJ, Ward PA. Extracellular histones are essential effectors of C5aR- and C5L2-mediated tissue damage and inflammation in acute lung injury. The FASEB Journal 2013 Dec; 27(12):5010-21 
• Erdmann J, Stark K, Esslinger UB, Rumpf PM, ... , Walter U; CARDIoGRAM, Ott J, Samani NJ, Strom TM, Meitinger T, Hengstenberg C, Schunkert H. Dysfunctional nitric oxide signalling increases risk of myocardial infarction. Nature 2013 Dec 19;504(7480):432-6. 
• Schnabel RB, Michal M, Wilde S, Wiltink J, Wild PS, Sinning CR, Lubos E, Ojeda FM, Zeller T, Munzel T, Blankenberg S, Beutel ME. Depression in atrial fibrillation in the general population. PLoS One 2013 Dec 4;8(12):e79109. 
• Rukoyatkina N, Mindukshev I, Walter U, Gambaryan S. Dual role of the p38 MAPK/cPLA2 pathway in the regulation of platelet apoptosis induced by ABT-737 and strong platelet agonists. Cell Death and Disease 2013 Nov 21;4:e931 
• Oelze M, Knorr M, Kroller-Schon S, Kossmann S, Gottschlich A, Rummler R, Schuff A, Daub S, Doppler C, Kleinert H, Gori T, Daiber A, Munzel T. Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression. European Heart Journal 2013 Nov;34(41):3206-16
• Hausding M, Jurk K, Daub S, Kröller-Schön S, Stein J, Schwenk M, Oelze M, Mikhed Y, Kerahrodi JG, Kossmann S, Jansen T, Schulz E, Wenzel P, Reske-Kunz AB, Becker C, Münzel T, Grabbe S, Daiber A. CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction. Basic Research in Cardiology 2013 Nov; 108(6):386. 
• Lankeit M, Dellas C, Benz V, Hasenfuß G, Konstantinides S. The predictive value of heart-type fatty acid-binding protein is independent from symptom duration in normotensive patients with pulmonary embolism. Thrombosis Research 2013 Nov;132(5):543-7 
• Tenzer S, Docter D, Kuharev J, Musyanovych A, Fetz V, Hecht R, Schlenk F, Fischer D, Kiouptsi K, Reinhardt C, Landfester K, Schild H, Maskos M, Knauer SK, Stauber RH. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nature Nanotechnology 2013 Oct; 8(10):772-81 
• Wiltink J, Michal M, Wild PS, Zwiener I, Blettner M, Münzel T, Schulz A, Kirschner Y, Beutel ME. Associations between depression and different measures of obesity (BMI, WC, WHtR, WHR). BMC Psychiatry 2013 Sep 12;13:223
• Casper I, Nowag S, Koch K, Hubrich T, Bollmann F, Henke J, Schmitz K, Kleinert H, Pautz A. Post-transcriptional regulation of the human inducible nitric oxide synthase (iNOS) expression by the cytosolic poly(A)-binding protein (PABP). Nitric Oxide 2013 Sep 1; 33:6-17
• Schroeter MR, Leifheit-Nestler M, Hubert A, Schumann B, Glückermann R, Eschholz N, Krüger N, Lutz S, Hasenfuss G, Konstantinides S, Schäfer K. Leptin promotes neointima formation and smooth muscle cell proliferation via NADPH oxidase activation and signalling in caveolin-rich microdomains. Cardiovascular Research 2013 Aug 1;99(3):555-65
• Subramanian H, Zahedi RP, Sickmann A, Walter U, Gambaryan S; Phosphorylation of CalDAG-GEFI by Protein Kinase A prevents Rap1b activation. Journal of Thrombosis and Haemostasis 2013 Aug; 11(8):1574-82 
• Bottolo L, Chadeau-Hyam M, Hastie DI, Zeller T, Liquet B, Newcombe P, Yengo L, Wild PS, Schillert A, Ziegler A, Nielsen SF, Butterworth AS, Ho WK, Castagné R, Munzel T, Tregouet D, Falchi M, Cambien F, Nordestgaard BG, Fumeron F, Tybjærg-Hansen A, Froguel P, Danesh J, Petretto E, Blankenberg S, Tiret L, Richardson S. GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm. PLoS Genetics 2013 Aug;9(8):e1003657 
• Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, Ojeda F, Muller-Nurasyid M, Munzel TF, Psaty BM, Rice K, Rotter JI, Schnabel RB, Tang WH, Thorand B, Erdmann J, Consortium C, Jacobs DR, Jr., Wilson JG, Koenig W, Tracy RP, Blankenberg S, Marz W, Gross MD, Benjamin EJ, Hazen SL, Allayee H. Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Human Molecular Genetics 2013 Aug 15; 22(16):3381-93
• Kröller-Schön S, Jansen T, Schüler A, Oelze M, Wenzel P, Hausding M, Kerahrodi JG, Beisele M, Lackner KJ, Daiber A, Münzel T, Schulz E. Peroxisome proliferator-activated receptor γ, coactivator 1α deletion induces angiotensin II-associated vascular dysfunction by increasing mitochondrial oxidative stress and vascular inflammation. Arteriosclerosis, Thrombosis and Vascular Biololgy 2013 Aug; 33(8):1928-35
• Leifheit-Nestler M, Wagner NM, Gogiraju R, Didié M, Konstantinides S, Hasenfuss G, Schäfer K. Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity. Journal of Translational Medicine 2013 Jul 11;11:170 
• Bosmann M, Haggadone MD, Zetoune FS, Sarma JV, Ward PA. The interaction between C5a and both C5aR and C5L2 receptors is required for production of G-CSF during acute inflammation. European Journal of Immunology 2013 Jul; 43(7):1907-13
• Schnabel RB, Biener MP, Wilde S, Sinning CR, Ojeda FM, Zeller T, Lubos E, Lackner KJ, Warnholtz A, Gori T, Espinola-Klein C, Blankenberg S, Munzel T, Wild PS. Sex differences in noninvasive vascular function in the community. Journal of Hypertension 2013 Jul;31(7):1437-46
• Fehrmanna C, Jurk K, Bertling A, Seidel G, Fegeler W, Kehrel BE, Peters G, Becker K, Heilmanna C. Role for the fibrinogen-binding proteins Coagulase and Efb in the Staphylococcus aureus–Candida interaction. International Journal of Medical Microbiology 2013 Jul; 303(5):230-8 
• Nuebling M, Seidler A, Garthus-Niegel S, Latza U, Wagner M, Hegewald J, Liebers F, Jankowiak S, Zwiener I, Wild PS, Letzel S. The Gutenberg Health Study: measuring psychosocial factors at work and predicting work-related outcomes with the ERI and the COPSOQ questionnaire. BMC Public Health 2013 Jun 4; 13:538 
• Kossmann S, Schwenk M, Hausding M, Karbach SH, Schmidgen MI, Brandt M, Knorr M, Hu H, Kröller-Schön S, Schönfelder T, Grabbe S, Oelze M, Daiber A, Münzel T, Becker C, Wenzel P. Angiotensin II-Induced Vascular Dysfunction Depends on Interferon-γ-Driven Immune Cell Recruitment and Mutual Activation of Monocytes and NK-Cells. Arteriosclerosis, Thrombosis, and Vascular Biology 2013 Jun; 33(6):1313-1319 
• Neumann JT, Tzikas S, Funke-Kaiser A, Wilde S, Appelbaum S, Keller T, Ojeda-Echevarria F, Zeller T, Zwiener I, Sinning CR, Jagodzinski A, Schnabel RB, Lackner KJ, Munzel T, Blankenberg S, Wild PS, Sydow K. Association of MR-proadrenomedullin with cardiovascular risk factors and subclinical cardiovascular disease. Atherosclerosis 2013 Jun; 228(2):451-9
• Falter T, Alber KJ, Scharrer I. Long term outcome and sequelae in patients after acute thrombotic thrombocytopenic purpura episodes. Hämostaseologie 2013 May 29; 33(2):113-20 
• Schroeter MR, Eschholz N, Herzberg S, Jerchel I, Leifheit-Nestler M, Czepluch FS, Chalikias G, Konstantinides S, Schäfer K. Leptin-dependent and leptin-independent paracrine effects of perivascular adipose tissue on neointima formation. Arteriosclerosis, Thrombosis and Vascular Biololgy 2013 May; 33(5):980-7
• Tzikas S, Keller T, Wild PS, Schulz A, Zwiener I, Zeller T, Schnabel RB, Sinning C, Lubos E, Kunde J, Munzel T, Lackner KJ, Blankenberg S. Midregional pro-atrial natriuretic peptide in the general population/Insights from the Gutenberg Health Study. Clinical Chemistry and Laboratory Medicine 2013 May; 51(5):1125-33 
• Mollnau H, Oelze M, Zinßius E, Hausding M, Wu Z, Knorr M, Ghaemi Kerahrodi J, Kröller-Schön S, Jansen T, Teutsch C, Foster C, Li H, Wenzel P, Schulz E, Münzel T, Daiber A. Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats. Naunyn-Schmiedebergs Arch Pharmacology 2013 May; 386(5):405-19 
• Gambaryan, Subramanian H, Rukoyatkina N, Herterich S, Walter U. Soluble guanylyl cyclase is the only enzyme responsible for cyclic guanosine monophosphate synthesis in human platelets. Journal of Thrombosis and Haemostasis 2013 May 2; 109(5):973-5 
• Bosmann M, Grailer JJ, Russkamp NF, Ruemmler R, Zetoune FS, Sarma JV, Ward PA. CD11c+ Alveolar Macrophages are a Source of IL-23 during LPS-induced Acute Lung Injury. Shock 2013 May; 39(5):447-52
• Michal M, Wiltink J, Lackner K, Wild PS, Zwiener I, Blettner M, Muenzel T, Schulz A, Kirschner Y, Beutel ME. Association of hypertension with depression in the community: results from the Gutenberg Health Study. Journal of Hypertension 2013; 31(5): 893-899 
• Michal M, Wiltink J, Reiner I, Kirschner Y, Wild PS, Schulz A, Zwiener I, Blettner M, Beutel ME. Association of mental distress with smoking status in the community: Results from the Gutenberg Health Study. JOURNAL OF AFFECTIVE DISORDERS 2013 Apr 25; 146(3):355-60 
• Bollmann F, Fechir K, Nowag S, Koch K, Art J, Kleinert H, Pautz A. Human inducible nitric oxide synthase (iNOS) expression depends on chromosome region maintenance 1 (CRM1)- and eukaryotic translation initiation factor 4E (elF4E)-mediated nucleocytoplasmic mRNA transport. Nitric Oxide 2013 Apr 1; 30:49-59 
• van der Loos MJ, Rietveld CA, ... Wild PS... Hofman A, Thurik AR. The molecular genetic architecture of self-employment. PLoS One 2013 Apr 4; 8(4):e60542
• Bosmann M, Meta F, Ruemmler R, Haggadone MD, Sarma JV, Zetoune FS, Ward PA. Regulation of IL-17 Family Members by Adrenal Hormones During Experimental Sepsis in Mice. American Journal of Pathology 2013 Apr; 182(4):1124-30
• Tzikas S, Keller T, Ojeda FM., Zeller T, Wild PS, Lubos E, Kunde J, Baldus S, Bickel C, Lackner KJ, Muenzel TF, Blankenberg S. MR-proANP and MR-proADM for risk stratification of patients with acute chest pain. Heart 2013 Mar; 99(6):388-95 
• Schweigel H, Geiger J, Beck F, Buhs S, Gerull H, Walter U, Sickmann A, Nollau P. Deciphering of ADP-induced, phosphotyrosinedependent signaling networks in human platelets by Src-homology 2 region (SH2)-profiling. Proteomics 2013 Mar;13(6):1016-27 
• Koettgen A, Albrecht E ... Wild PS ... , Bochud M, Gieger C. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. NATURE GENETICS 2013 Feb; 45(2):145-54 
• Bugl S, Wirths S, Radsak M, Schild H, Stein P, André M, Müller M, Malenke E, Wiesner T, Märklin M, Frick J, Handgretinger R, Rammensee H, Kanz L and Kopp H. Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling. Blood 2013 Jan 31; 121(5):723-33 
• Deloukas P, Kanoni S ... Wild PS ... Schunkert H, Samani NJ. Large-scale association analysis identifies new risk loci for coronary artery disease. NATURE GENETICS 2013 Jan; 45(1):25-33 
• Verdugo RA, Zeller T, Rotival M, Wild PS, Munzel T, Lackner KJ, Weidmann H; Ninio E, Tregouet DA, Cambien F, Blankenberg S, Tiret L. Graphical modeling of gene expression in monocytes suggests molecular mechanisms explaining increased atherosclerosis in smokers. Plos One 2013; 8(1):e50888 
• Begonja AJ, Gambaryana S, Schulzed H, Patel-Hett S, Italiano JE, Hartwigb JH, Walter U. Differential roles of cAMP and cGMP in megakaryocyte maturation and platelet biogenesis. Experimental Hematology 2013;41:91–101
• Hausding M, Jurk K, Daub S, Kröller-Schön S, Stein J, Schwenk M, Oelze M, Mikhed Y, Ghaemi Kerahrodi J,  Kossmann S,  Jansen T,  Schulz E,  Wenzel P, Reske-Kunz AB, Becker C, Münzel T, Grabbe S, Daiber A. CD40L contributes to angiotensin II-induced pro-thrombotic state, vascular inflammation, oxidative stress and endothelial dysfunction. Basic Research in Cardiology 2013; 108:386
• Garnier S, Truong V, Brocheton J, Zeller T, Rovital M, Wild PS, Ziegler A; Cardiogenics Consortium, Munzel T, Tiret L, Blankenberg S, Deloukas P, Erdmann J, Hengstenberg C, Samani NJ, Schunkert H, Ouwehand WH, Goodall AH, Cambien F, Trégouët DA. Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes. PLoS Genet. 2013;9(1):e1003240. 

Reviews 2013

• Bosmann M, Ward PA. 2013. Modulation of inflammation by interleukin-27. J Leukoc Biol. 94:1159-1165, 2013.
• Lankeit M, Konstantinides S. Aktuelle Therapie und Sekundärprävention der Lungenembolie. Pneumologe 2013 2013 Nov; 443-456. CME-zertifizierte Fortbildung 
• Lankeit M, Konstantinides S. Aktuelle Therapie und Sekundärprävention der Lungenembolie. Der Kardiologe 2013; 7:217-230. doi:10.1007/s12181-013-0481-8. CME-zertifizierte Fortbildung
• Danckwardt S, Hentze MW, Kulozik AE. Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond. Journal of Molecular Medicine 2013 Nov; 91(11):1257-71. 
• Versteeg H. H., Ruf W. New helpers in TF-dependent migration. Journal of Thrombosis and Haemostasis 2013 Oct; 11(10): 1877-9 
• Münzel T, Daiber A, Gori T. More answers to the still unresolved question of nitrate tolerance. European Heart Journal. 2013 Sep; 34(34):2666-73 
• den Exter P.L, van der Hulle T, Lankeit M, Huisman M.V., Klok F.A. Long-term clinical course of acute pulmonary embolism. Blood Reviews 2013 Jul; 27(4):185-92. 
• Li H, Horke S, Förstermann U. Oxidative stress in vascular disease and its pharmacological prevention Trends in Pharmacological Sciences. Trends Pharmacol Science 2013 Jun; 34(6):313-9 
• Konstantinides S, Lankeit M. Pulmonary embolism hotline 2012. Recent and expected trials. Hamostaseologie 2013 Feb; 33(1):43-50. 

Editorials und Fachbeiträge 2013

• Mirshahi A, Ponto KA, Hohn R, Wild PS, Pfeiffer N. Ophthalmological aspects of the Gutenberg Health Study (GHS): an interdisciplinary prospective population-based cohort study. Ophthalmologe 2013 Mar; 110(3):210-7 (P1B)
• Lankeit M, Konstantinides S. Lungenembolie - Update 2013. Deutsche Medizinische Wochenschrift 138. Jahrgang, 31/32 2013 (P1C)
• Konstantinides S, Lankeit M. Diagnostik im Dialog. News der Roche Diagnostics Deutschland GmbH 2013, Ausgabe 39, 2/2013 (P1C)
• Schinzel H, Hendelmeier M. Therapie der frischen tiefen Beinvenenthrombose. Deutsche Medizinische Wochenschrift 2013, 138: 786-791
• Konstantinides S, Lankeit M. Risikostratifizierung bei Lungenembolie: Stellwert kardialer Troponine. Diagnostik im Dialog 2013; Ausgabe 29, 2/2013 (JG1C)

Originalartikel 2012

• Bosmann M, Russkamp NF, Ward PA. Fingerprinting of the TLR4-induced acute inflammatory response. Experimental and Molecular Pathology 2012 Dec; 93(3):319-23 
• Schurmann C, Heim K, Schillert A, Blankenberg S, Carstensen M, Dörr M, Endlich K, Felix SB, Gieger C, Grallert H, Herder C, Hoffmann W, Homuth G, Illig T, Kruppa J, Meitinger T, Müller C, Nauck M, Peters A, Rettig R, Roden M, Strauch K, Völker U, Völzke H, Wahl S, Wallaschofski H, Wild PS, Zeller T, Teumer A, Prokisch H, Ziegler A. Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLOS one 2012 Dec; 7(12):e50938 
• Kröller-Schön S, Knorr M, Hausding M, Oelze M, Schuff A, Schell R, Sudowe S, Scholz A, Daub S, Karbach S, Kossmann S, Gori T, Wenzel P, Schulz E, Grabbe S, Klein T, Münzel T, Daiber A. Glucose Independent Improvement of Vascular Dysfunction in Experimental Sepsis by Dipeptidyl-Peptidase 4 Inhibition. Cardiovascular Research 2012 Oct 1; 96(1):140-9 
• Burkhart J, Vaudel M, Gambaryan S, Radau S, Walter U, Martens L, Geiger J, Sickmann A, Zahedi R. The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood 2012 Oct 11;120(15):e73-82 
• Siuda D, Zechner U, El Hajj N, Prawitt D, Langer D, Xia N, Horke S, Pautz A, Kleinert H, Förstermann U, Li H. Transcriptional regulation of Nox4 by histone deacetylases in human endothelial cells. Basic Research in Cardiology 2012 Sep; 107:283 
• Schnabel R, Wild P, Schulz A, Zeller T, Sinning C, Wilde S, Kunde J, Lubos E, Lackner K, Warnholtz A, Gori T, Blankenberg S, Munzel T. Multiple Endothelial Biomarkers and Noninvasive Vascular Function in the General Population The Gutenberg Health Study. Hypertension 2012 Aug; 60(2):288-95 
• Kroller-Schon S, Jansen T, Hauptmann F, Schuler A, Heeren T, Hausding M, Oelze M, Viollet B, Keaney JF, Jr., Wenzel P, Daiber A, Munzel T, Schulz E. alpha1AMP-Activated Protein Kinase Mediates Vascular Protective Effects of Exercise. Arteriosclerosis Thrombosis and Vascular Biology 2012 Jul; 32(7):1632-41
• Closs E, Ostad M, Simo A, Warnholtz A, Jabs A, Habermeier A, Daiber A, Förstermann U, Münzel T. Impairment of the extrusion transporter for asymmetric dimethyl-L-arginine: a novel mechanism underlying vasospastic angina. Biochem. Biophys. Res. Commun 2012 Jun 29; 423(2):218-23 
• Wild P, Zeller T, Beutel M, Blettner M, Dugi  K, Lackner K, Pfeiffer N, Munzel T, Blankenberg S. Die Gutenberg Gesundheitsstudie. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz 2012 Jun, Volume 55; Issue: 6-7; Pages: 824-829
• Gambaryan S, Friebe A, Walter U. Does the NO/sGC/cGMP/PKG pathway play a stimulatory role in platelets? Blood 2012 May; 119:5335-5336 
• Schnabel RB, Wilde S, Wild PS, Munzel T, Blankenberg S. Atrial Fibrillation: Its Prevalence and Risk Factor Profile in the German General Population. Deutsches Ärzteblatt International 2012 Apr; 109(16):293-9 
• Reinhardt C, Bergentall M, Greiner TU, Schaffner F, Ostergren-Lundén G, Petersen LC, Ruf W, Bäckhed F. Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodeling. Nature 2012 Mar 11; 483(7391):627-31 
• Wild P, Schnabel R, Lubos E, et al. Midregional Proadrenomedullin for Prediction of Cardiovascular Events in Coronary Artery Disease: Results from the AtheroGene Study. Clinical Chemistry 2012 Jan; 58(1):226-36 
• Torzewski M, Wenzel P, Kleinert H, Becker C, El-Masri J, Wiese E, Brandt M, Pautz A, Twardowski L, Schmitt E, Münzel T, Reifenberg K. Chronic Inflammatory Cardiomyopathy of Interferon gamma-Overexpressing Transgenic Mice Is Mediated by Tumor Necrosis Factor-alpha. American Journal of Pathology 2012 Jan; 180(1):73-81
• Knorr M, Hausding M, Schulz E, Oelze M, Rümmler R, Schuff A, Daub S, Schreiner J, Kröller-Schön S, Wenzel P, Gori T, Burgin K, Sartor D, Scherhag A, Münzel T, Daiber A. Characterization of new organic nitrate hybrid drugs covalently bound to valsartan and cilostazol. Pharmacology 2012; 90(3-4):193-204
• Gladigau G, Haselmayre P, Scharrer I, Munder M, Prinz N, Lackner K, Schild H, Stein P, Radsak M. A Role for Toll-Like Receptor Mediated Signals in Neutrophils in the Pathogenesis of the Anti-Phospholipid Syndrome. PLOS one 2012; 7(7): e42176 

Reviews 2012

• Konstantinides S, Goldhaber SZ. Pulmonary embolism: risk assessment and management. European Heart Journal 2012 Dec; 33(24):3014-22
• Nickel K, Renné T. Crosstalk of the plasma contact system with bacteria.Thrombosis Research 2012 Oct; 130 Suppl 1:S78-83 
• Renné T, Schmaier AH, Nickel KF, Blombäck M, Maas C. In vivo roles of factor XII. Blood 2012 Sep, 120: 4296-4303 
• Renné T. The procoagulant and proinflammatory plasma contact system. Seminars in Immunopathology 2012 Aug; 34:31-41 
• Mass C, Renné T. Regulatory mechanisms of the plasma contact system. Thrombosis Research 2012 May; 129 Suppl 2:S73-6 
• Konstantinides S, Münzel T. Apixaban. Hamostaseologie 2012; 32(3):203-11 
• Daiber A, Oelze M, Wenzel P, Bollmann F, Pautz A, Kleinert H. Heme Oxygenase-1 Induction and Organic Nitrate Therapy: Beneficial Effects on Endothelial Dysfunction, Nitrate Tolerance, and Vascular Oxidative Stress. International Journal of Hypertension 2012; 2012:842632, doi:10.1155/2012/842632 (TRP A1, A2)

Editorials und Fachbeiträge 2012

• Bollmann F, Casper I, Henke J, Pautz A. qRT-PCR: a method and its difficulties. Naunyn Schmiedebergs Arch Pharmacology 2012 Oct; 385(10):949-51

Originalartikel 2011

• Kroller-Schon S, Schulz E, Wenzel P, Kleschyov A, Hortmann M, Torzewski M, Oelze M, Renne T, Daiber A, Munzel T. Differential effects of heart rate reduction with ivabradine in two models of endothelial dysfunction and oxidative stress. Basic Research in Cardiology 2011 Nov; 106:1147-1158 

• Schuhmacher S, Oelze M, Bollmann F, Kleinert H, Otto C, Heeren T, Steven S, Hausding M, Knorr M, Pautz A, Reifenberg K, Schulz E, Gori T, Wenzel P, Munzel T, Daiber A. Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy. Diabetes 2011 Oct; 60:2608-2616 

• Knorr M, Hausding M, Kroller-Schuhmacher S, Steven S, Oelze M, Heeren T, Scholz A, Gori T, Wenzel P, Schulz E, Daiber A, Munzel T. Nitroglycerin-induced endothelial dysfunction and tolerance involve adverse phosphorylation and S-Glutathionylation of endothelial nitric oxide synthase: beneficial effects of therapy with the AT1 receptor blocker telmisartan. Arteriosclerosis Thrombosis and Vascular Biology 2011 Oct; 31(10):2223-31

• Wenzel P, Knorr M, Kossmann S, Stratmann J, Hausding M, Schuhmacher S, Karbach S, Schwenk M, Yogev N, Schulz E, Oelze M, Grabbe S, Jonuleit H, Becker C, Daiber A, Waisman A, Münzel T. Lysozyme M–Positive Monocytes Mediate Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction. Circulation 2011 Sept; 124:1370-1381 

• Schuhmacher S, Foretz M, Knorr M, Jansen T, Hortmann M, Wenzel P, Oelze M, Kleschyov A, Daiber A, Keaney J, Wegener G, Lackner K, Münzel T, Viollet B, Schulz E. α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation. Arteriosclerosis Thrombosis and Vascular Biology 2011 Mar; 31(3):560-6 

Reviews 2011

• Müller F, Gailani D, Renné T. Factor XI and XII as antithrombotic targets. Current Opinion in Hematology 2011 Sep; 18(5):349-55
• Münzel T, Daiber A, Gori T. Nitrate Therapy: New Aspects Concerning Molecular Action and Tolerance. Circulation 2011 May; 123(5); 2132-2144 
• Damaske A, Muxel S, Fasola F, Radmacher MC, Schaefer S, Jabs A, Orphal D, Wild P, Parker JD, Fineschi M, Munzel T, Forconi S, Gori T. Peripheral hemorheological and vascular correlates of coronary blood flow. Clinical Hemorheology and Microcirculation 2011; 49(1-4):261-9

CTH verbundene Autoren sind in Kursivschrift.