Logo der Universitätsmedizin Mainz

Mainz Research School of Translational Biomedicine
(TransMed)

Visual Universitätsmedizin Mainz

AG Molekulare Tumorbiologie

  • Arbeitsgruppenleiter:in: Prof. Dr. Jürgen Brieger

  • Forschungsschwerpunkte:

    Tumorangiogenese, Strahlenresistenz, Nanotoxikologie, Drug targeting, Implantat-Gewebe-Homöostase

  • Fünf wichtigste Publikationen:

    Watermann A, Gieringer R, Bauer AM, Kurch S, Kiesslich R, Tremel W, Gosepath J, Brieger J. Fluorescein- and EGFR-Antibody Conjugated Silica Nanoparticles for Enhancement of Real-time Tumor Border Definition Using Confocal Laser Endomicroscopy in Squamous Cell Carcinoma of the Head and Neck. Nanomaterials (Basel). 2019 Sep 26;9(10). pii: E1378. doi: 10.3390/nano9101378. PubMed PMID: 31561451; PubMed Central PMCID: PMC6835239.

    Wiesmann N, Gieringer R, Grus F, Brieger J. Phosphoproteome Profiling Reveals Multifunctional Protein NPM1 as part of the Irradiation Response of Tumor Cells. Transl Oncol. 2019 Feb;12(2):308-319. doi: 10.1016/j.tranon.2018.10.015. Epub 2018 Nov 16. PubMed PMID: 30453269; PubMed Central PMCID: PMC6240713.

    Wiesmann N, Kluenker M, Demuth P, Brenner W, Tremel W, Brieger J. Zinc overload mediated by zinc oxide nanoparticles as innovative anti-tumor agent. J Trace Elem Med Biol. 2019 Jan;51:226-234. doi: 10.1016/j.jtemb.2018.08.002. Epub 2018 Aug 7. PubMed PMID: 30115501.

    Wiesmann N, Strozynski J, Beck C, Zimmermann N, Mendler S, Gieringer R, Schmidtmann I, Brieger J. Knockdown of hnRNPK leads to increased DNA damage after irradiation and reduces survival of tumor cells. Carcinogenesis. 2017 Mar 1;38(3):321-328. doi: 10.1093/carcin/bgx006. PubMed PMID: 28426877.

    Heim J, Felder E, Tahir MN, Kaltbeitzel A, Heinrich UR, Brochhausen C, Mailänder V, Tremel W, Brieger J. Genotoxic effects of zinc oxide nanoparticles. Nanoscale. 2015 May 21;7(19):8931-8. doi: 10.1039/c5nr01167a. PubMed PMID: 25916659.


Logo.png
Ansprechpartnerin:

 

Sabine Tensing

Programmkoordination
MAInz-DOC-Promotionskolleg

Tel +49 6131 17-7632
 E-Mail