Visual Universitätsmedizin Mainz

AG Adult Neurogenese und zelluläre Reprogrammierung

  • Arbeitsgruppenleiter/-in: Prof. Dr. Benedikt Berninger
  • Forschungsschwerpunkte:

    Adulte Neurogenese
    Reprogrammierung von Glia in Neurone


  • Fünf wichtigste Publikationen:

    Tiwari N, Pataskar A, Péron S, Thakurela S, Sahu SK, Figueres-Oñate M, Marichal N, López-Mascaraque L, Tiwari VK, Berninger B (2018). Stage-specific transcription factors drive astrogliogenesis by remodeling gene regulatory landscapes. Cell Stem Cell 23:557-571.

    Karow M, Camp JG, Falk S, Gerber T, Pataskar A, Gac-Santel M, Kageyama J, Brazovskaja A, Garding A, Fan W, Riedemann T, Casamassa A, Smiyakin A, Schichor C, Götz M, Tiwari VK, Treutlein B, Berninger B (2018). Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nature Neuroscience 21:932-940.

    Gascón S, Mureno E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Roberston SP, Schroeder T, Beckers J, Irmler M, Berndt C, Friedmann Angeli JP, Conrad M, Berninger B, Götz M (2016). Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming. Cell Stem Cell 18: 396-409.

    Bergami M, Masserdotti G, Temprana SG, Motori E, Eriksson T, Göbel J, Yang SM, Conzelmann K-K, Schinder AF, Götz M, Berninger B (2015) A critical period of experience-dependent remodelling of adult-born neuron connectivity. Neuron 85: 710-717.

    Ortega F, Gascón S, Masserdotti G, Deshpande A, Simon S, Fischer J, Dimou L, Lie DC, Schroeder T, Berninger B (2013) Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signaling. Nature Cell Biology 15: 602-613.

 

 

Ansprechpartnerin:

 

Sabine Tensing

Programmkoordination
MAInz-DOC-Promotionskolleg

Tel +49 6131 17-7632
 E-Mail